Hub : Genes

ENSRNOG00000064438

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000064438 0.1 0.09 4.1e-08 0.06 0.06 0.06 0.06 3.6e-07 4.1e-07 4.5e-07 4.4e-07
2 BLA isoform ratio ENSRNOT00000101301 0.06 0.06 3.1e-03 0.02 0 0.02 0.01 3.7e-02 3.4e-01 2.5e-02 1.5e-01
3 BLA isoform ratio ENSRNOT00000101388 0.06 0.06 3.0e-03 0.01 -0 0.02 0 5.6e-02 3.4e-01 2.5e-02 2.0e-01
4 Brain gene expression ENSRNOG00000064438 0.08 0.07 3.3e-06 0.04 0.06 0.05 0.05 1.4e-04 6.3e-06 2.0e-05 3.5e-05
5 IL gene expression ENSRNOG00000064438 0.2 0.18 2.0e-03 0.1 0.09 0.1 0.1 2.8e-03 3.2e-03 2.8e-03 2.8e-03
6 LHb gene expression ENSRNOG00000064438 0.3 0.28 3.1e-04 0.12 0.13 0.13 0.16 7.3e-04 5.9e-04 5.1e-04 1.4e-04
7 LHb isoform ratio ENSRNOT00000101301 0.15 0.14 6.6e-03 0.1 0.08 0.05 0.13 2.0e-03 5.1e-03 2.4e-02 6.1e-04
8 LHb isoform ratio ENSRNOT00000101388 0.14 0.14 8.3e-03 0.11 0.07 0.04 0.12 1.7e-03 8.8e-03 3.6e-02 1.1e-03
9 NAcc gene expression ENSRNOG00000064438 0.78 0.09 5.4e-06 0.03 0.04 0.05 0.03 2.9e-03 3.2e-04 1.6e-04 1.9e-03
10 OFC gene expression ENSRNOG00000064438 0.31 0.25 8.4e-04 0.06 0.05 0.08 0.06 1.5e-02 2.4e-02 6.2e-03 1.9e-02
11 PL gene expression ENSRNOG00000064438 0.06 0.06 8.9e-05 0.04 0.05 0.01 0.04 8.4e-04 6.6e-05 3.9e-02 3.2e-04
12 PL isoform ratio ENSRNOT00000101301 0.47 0.25 3.1e-03 0.01 0.01 -0 0 6.9e-02 2.6e-02 7.3e-01 1.2e-01
13 PL isoform ratio ENSRNOT00000101388 0.57 0.24 7.0e-04 0.01 0.02 0 0.01 4.2e-02 1.5e-02 1.8e-01 9.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.00.20.60.40.4-0.4-0.40.00.00.00.0-0.80.5-0.4-0.4-0.0
BMI without tail16.735.0359.60.80.3-0.4-0.80.00.00.00.0-2.50.4-1.0-9.319.0
Body weight1.56.547.31.51.3-1.3-1.50.00.00.00.0-2.91.3-1.6-4.26.9
Epididymis fat weight14.634.0317.92.11.5-1.6-2.00.00.00.00.0-3.71.5-2.2-9.517.8
Glucose1.32.110.1-1.3-1.31.31.20.00.00.00.01.5-1.11.32.3-3.2
Heart weight1.21.716.3-0.4-0.30.30.40.00.00.00.00.2-0.50.52.2-4.0
Left kidney weight5.816.7179.9-0.4-0.90.90.50.00.00.00.0-0.2-0.70.3-5.913.4
Right kidney weight6.618.9192.00.80.3-0.4-0.70.00.00.00.0-2.20.3-0.8-6.813.9
Tail length9.428.4275.41.61.1-1.2-1.50.00.00.00.0-2.51.1-1.8-8.716.6
Length with tail1.14.114.61.91.8-1.8-1.90.00.00.00.0-2.91.6-1.9-3.03.8
Length without tail11.224.4262.30.81.3-1.2-0.80.00.00.00.0-0.71.0-0.66.9-16.2
Liver weight, left2.43.938.1-1.0-1.31.21.10.00.00.00.01.0-1.11.0-2.16.2
Liver weight, right1.01.615.90.30.3-0.3-0.30.00.00.00.01.40.4-0.31.5-4.0
Parametrial fat weight2.75.351.61.11.4-1.3-1.10.00.00.00.0-1.41.1-1.02.6-7.2
Retroperitoneal fat weight0.62.113.91.10.9-1.0-1.10.00.00.00.0-1.00.9-1.1-2.53.7
Intraocular pressure3.85.341.5-0.9-0.80.80.80.00.00.00.03.3-0.60.93.5-6.4
Extensor digitorum longus weight4.517.9157.2-2.0-1.81.81.90.00.00.00.02.2-1.62.17.1-12.5
Soleus weight2.26.563.90.60.3-0.4-0.50.00.00.00.0-1.90.3-0.6-4.08.0
Tibialis anterior weight9.432.3330.9-1.1-0.50.61.00.00.00.00.01.1-0.71.29.1-18.2
Tibia length1.43.920.91.51.4-1.4-1.40.00.00.00.0-2.91.2-1.5-3.04.6
Number of licking bursts24.929.4287.01.81.2-1.3-1.70.00.00.00.0-1.31.3-1.9-8.916.9
Food consumed during 24 hour testing period1.92.221.0-0.1-0.00.00.10.00.00.00.02.00.30.12.0-4.6
Times rat made contact with spout11.713.3139.0-0.5-0.00.10.40.00.00.00.00.8-0.20.65.7-11.8
Mean time between licks in bursts8.511.8126.1-0.10.2-0.20.10.00.00.00.00.70.10.25.2-11.2
Mean num. licks in bursts26.131.4311.2-1.6-1.01.11.50.00.00.00.01.0-1.21.79.2-17.6
Std. dev. time between licks in bursts27.432.7347.40.3-0.40.3-0.20.00.00.00.00.6-0.1-0.4-8.818.6
Water consumed over 24 hours0.80.96.8-0.2-0.40.30.20.00.00.00.01.7-0.00.1-1.22.6
Indifference point 0 sec6.310.234.33.43.2-3.2-3.40.00.00.00.0-2.53.3-3.4-5.15.9
Indifference point AUC6.77.978.30.70.5-0.5-0.70.00.00.00.0-1.10.5-0.8-4.58.8
Indifference point function ln k0.60.86.20.80.9-0.9-0.80.00.00.00.00.40.9-0.80.5-2.5
Indifference point function log k0.60.86.20.80.9-0.9-0.80.00.00.00.00.40.9-0.80.5-2.5
Delay discounting total patch changes 0 sec6.09.832.63.33.1-3.2-3.30.00.00.00.0-2.53.3-3.4-5.05.7
Delay discounting total patch changes 12 sec17.022.7208.52.01.5-1.5-1.90.00.00.00.0-1.51.7-2.1-8.014.4
Delay discounting total patch changes 18 sec27.836.7366.81.50.9-1.0-1.40.00.00.00.0-2.01.0-1.7-9.819.2
Delay discounting total patch changes 24 sec4.65.854.90.90.7-0.7-0.80.00.00.00.0-0.90.7-0.9-4.07.4
Delay discounting total patch changes 6 sec17.626.8221.02.92.4-2.4-2.80.00.00.00.0-2.22.7-3.0-8.914.9
Delay discounting time to switch 0 sec0.00.00.5-0.1-0.10.10.10.00.00.00.0-0.7-0.10.10.2-0.2
Delay discounting water rate 0 sec1.52.418.71.00.9-0.9-0.90.00.00.00.0-0.40.9-1.0-2.74.3
Delay discounting water rate 12 sec4.26.466.20.50.9-0.8-0.60.00.00.00.0-1.50.5-0.43.5-8.1
Delay discounting water rate 18 sec1.01.413.9-0.5-0.60.60.50.00.00.00.00.1-0.60.4-1.43.7
Delay discounting water rate 24 sec9.713.4139.20.60.2-0.2-0.50.00.00.00.0-0.60.4-0.7-5.811.8
Delay discounting water rate 6 sec7.010.2102.20.80.5-0.5-0.70.00.00.00.0-1.20.5-0.8-5.110.1
Locomotor activity2.43.87.22.52.5-2.5-2.50.00.00.00.0-2.72.2-2.5-2.21.2
Locomotor testing distance3.76.223.22.52.4-2.4-2.50.00.00.00.0-2.72.1-2.5-3.94.8
Locomotor testing rearing3.45.437.51.71.5-1.6-1.70.00.00.00.0-1.51.3-1.7-3.96.1
Light reinforcement 19.417.1154.01.81.4-1.5-1.70.00.00.00.0-2.61.4-1.9-6.812.4
Light reinforcement 20.50.74.90.70.8-0.8-0.70.00.00.00.0-0.70.7-0.70.6-2.2
Reaction time number correct1.01.513.50.50.7-0.7-0.60.00.00.00.0-1.30.5-0.51.4-3.7
Reaction time mean minus median1.51.93.8-1.6-1.61.61.60.00.00.00.02.0-1.61.61.8-1.5
Reaction time mean minus median AUC1.11.42.6-1.5-1.41.51.50.00.00.00.01.1-1.61.51.6-1.2
Reaction time num false alarms8.912.2124.10.80.4-0.5-0.70.00.00.00.0-0.90.5-0.9-5.611.1
Reaction time num false alarms AUC12.417.4179.50.70.3-0.4-0.60.00.00.00.0-1.40.3-0.8-6.613.4
Reaction time trials correct on left1.01.513.50.50.7-0.7-0.60.00.00.00.0-1.30.5-0.51.4-3.7
Reaction time trials on left1.11.614.70.50.7-0.7-0.50.00.00.00.0-1.30.4-0.51.5-3.8
Reaction time mean7.19.785.8-1.5-1.11.21.40.00.00.00.01.6-1.31.55.3-9.3
Reaction time mean AUC9.612.8118.7-1.4-1.01.11.40.00.00.00.01.6-1.21.56.0-10.9
Median of all reaction times8.211.1108.6-1.0-0.60.70.90.00.00.00.01.2-0.71.15.5-10.4
Reaction time omissions0.60.75.2-0.8-0.90.90.80.00.00.00.02.3-0.70.80.7-0.4
Reaction time false alarm rate9.813.8147.60.2-0.20.2-0.10.00.00.00.0-0.3-0.1-0.3-5.712.1
Reaction time premature initiation rate6.48.663.61.71.5-1.5-1.70.00.00.00.0-3.01.6-1.8-4.88.0
Reaction time premature initiations7.210.370.92.11.9-1.9-2.00.00.00.00.0-3.61.8-2.1-5.28.4
Std. dev. reaction times2.83.837.0-0.7-0.40.40.60.00.00.00.00.1-0.60.73.3-6.1
Reaction time trials completed1.11.614.70.50.7-0.7-0.50.00.00.00.0-1.30.4-0.51.5-3.8
Reaction time trials AUC1.52.222.30.40.7-0.6-0.50.00.00.00.0-1.10.4-0.41.9-4.7
Social response proportion0.50.54.30.40.3-0.3-0.40.00.00.00.00.50.4-0.5-1.32.1
Social responses14.618.9140.52.72.4-2.4-2.60.00.00.00.0-4.02.1-2.7-7.211.9
Social time0.91.110.10.60.8-0.8-0.70.00.00.00.0-0.80.6-0.61.0-3.2
Conditioned locomotion0.50.61.41.01.0-1.0-1.00.00.00.00.0-1.21.0-1.0-0.7-0.0
Cocaine response after cond. corrected12.914.4152.1-1.2-1.61.61.30.00.00.00.01.0-1.61.1-4.812.3
Cocaine response after cond. not corrected16.618.5196.1-1.1-1.71.61.20.00.00.00.01.1-1.51.0-5.614.0
Cocaine response before conditioning2.73.334.80.0-0.20.2-0.00.00.00.00.00.00.1-0.1-2.75.9
Saline control response4.76.367.4-0.1-0.40.40.20.00.00.00.00.6-0.30.0-3.78.2
Condit. Reinf. active minus inactive responses4.75.857.50.70.4-0.4-0.60.00.00.00.0-0.50.4-0.7-3.97.6
Condit. Reinf. active-inactive response ratio6.46.771.9-0.3-0.60.60.40.00.00.00.00.4-0.60.3-3.68.5
Condit. Reinf. active responses1.41.915.40.80.7-0.7-0.80.00.00.00.0-0.90.6-0.8-2.33.9
Condit. Reinf. inactive responses2.12.625.60.81.0-1.0-0.80.00.00.00.0-0.70.9-0.81.8-5.1
Condit. Reinf. lever presses0.40.52.60.80.9-0.9-0.80.00.00.00.0-0.20.7-0.80.2-1.6
Condit. Reinf. lever reinforcers received0.10.10.20.40.5-0.5-0.40.00.00.00.0-0.40.4-0.4-0.40.2
Pavlov. Cond. lever latency5.87.983.0-0.1-0.40.40.20.00.00.00.0-1.7-0.30.1-4.19.1
Pavlov. Cond. magazine entry latency16.719.1199.0-0.10.3-0.20.10.00.00.00.02.70.20.26.5-14.1
Pavlov. Cond. change in total contacts20.428.4302.20.10.6-0.6-0.20.00.00.00.02.30.60.07.8-17.4
Pavlov. Cond. index score10.213.3133.5-0.30.0-0.00.20.00.00.00.03.10.00.35.4-11.6
Pavlov. Cond. latency score11.114.0139.6-0.30.0-0.00.20.00.00.00.03.40.10.35.5-11.8
Pavlov. Cond. lever contacts2.83.941.00.50.7-0.7-0.50.00.00.00.01.20.5-0.42.6-6.4
Pavlov. Cond. magazine entry number23.929.4301.40.60.1-0.2-0.50.00.00.00.0-3.40.1-0.7-8.217.4
Pavlov. Cond. intertrial magazine entries10.113.0136.90.0-0.20.20.00.00.00.00.0-2.1-0.4-0.1-5.311.7
Pavlov. Cond. lever-magazine prob. diff.9.011.6117.3-0.20.0-0.00.20.00.00.00.02.90.10.35.0-10.8
Pavlov. Cond. response bias5.17.070.70.00.2-0.2-0.10.00.00.00.02.30.20.03.8-8.4
Conditioned reinforcement - actives2.52.518.2-1.2-0.90.81.10.00.00.00.00.6-0.91.12.7-4.3
Conditioned reinforcement - inactives0.30.40.80.70.9-0.9-0.80.00.00.00.0-0.40.9-0.8-0.2-0.7
Conditioned locomotion1.01.111.8-0.10.5-0.5-0.10.00.00.00.0-0.10.4-0.11.5-3.4
Intermittent access intake day 1-15 change9.89.8103.20.21.2-1.2-0.50.00.00.00.00.61.1-0.44.3-10.2
Intermittent access intake escalation13.413.2139.00.51.6-1.6-0.80.00.00.00.00.51.6-0.74.9-11.8
Intermittent access intake escalation 24.14.042.20.40.9-0.9-0.50.00.00.00.00.50.9-0.42.6-6.5
Intermitt. access day 1 inactive lever presses3.13.433.1-0.6-0.10.10.50.00.00.00.01.1-0.10.63.0-5.8
Intermitt. access day 15 inactive lever presses0.40.52.50.50.8-0.9-0.70.00.00.00.0-0.20.8-0.70.3-1.6
Intermitt. access escalation Index1.11.08.2-0.6-0.30.30.40.00.00.00.00.7-0.40.41.6-2.9
Intermittent access day 1 total infusions5.25.959.80.40.1-0.1-0.30.00.00.00.0-1.40.1-0.4-3.87.7
Intermittent access day 15 total infusions0.50.61.40.71.2-1.2-0.90.00.00.00.0-1.01.1-0.9-0.2-0.9
Intermittent access terminal intake (last 3 days)0.10.10.4-0.7-0.30.30.50.00.00.00.00.4-0.30.50.30.1
Intermittent access total infusions0.30.42.50.20.4-0.5-0.30.00.00.00.0-0.70.4-0.3-0.91.6
Intermittent access day 1 locomotion3.53.627.70.90.9-0.9-1.10.00.00.00.0-1.60.9-1.1-3.15.3
Intermittent access day 15 total locomotion1.51.63.31.51.8-1.8-1.50.00.00.00.0-1.81.7-1.5-0.8-0.6
Intermittent access total locomotion0.91.02.11.11.4-1.4-1.30.00.00.00.0-1.21.4-1.3-1.10.5
Intermittent access standard deviation0.00.00.1-0.2-0.10.10.20.00.00.00.0-0.1-0.10.20.3-0.2
Cocaine induced anxiety0.40.43.1-0.4-0.40.50.40.00.00.00.00.3-0.50.41.1-1.7
Post-drug Anxiety2.32.522.7-0.8-0.50.50.80.00.00.00.00.4-0.50.82.7-4.8
Baseline Anxiety0.60.64.40.50.8-0.8-0.50.00.00.00.0-0.70.8-0.50.6-2.1
Lifetime Intake0.10.10.2-0.5-0.20.20.40.00.00.00.00.0-0.30.40.10.4
Incentive Sensitization - Responses0.60.62.80.60.7-0.7-0.70.00.00.00.0-1.70.7-0.7-0.91.0
Incentive Sensitization - Breakpoint0.40.42.20.40.4-0.4-0.40.00.00.00.0-1.50.4-0.5-0.91.2
Progressive ratio test 1 active lever presses1.21.212.20.20.2-0.2-0.30.00.00.00.00.10.2-0.3-1.83.5
Progressive ratio test 1 breakpoint1.01.010.7-0.3-0.30.20.20.00.00.00.00.6-0.20.2-1.33.3
Progressive ratio test 1 inactive lever presses1.21.311.6-0.5-0.20.20.50.00.00.00.00.6-0.20.51.9-3.4
Progressive ratio test 2 active lever presses1.41.513.00.50.5-0.5-0.50.00.00.00.0-1.10.5-0.6-2.03.6
Progressive ratio test 2 breakpoint6.26.968.40.50.2-0.3-0.60.00.00.00.0-1.60.2-0.7-4.28.3
Progressive ratio test 2 inactive lever presses0.20.21.7-0.4-0.10.10.30.00.00.00.00.5-0.10.40.8-1.3
Total sessions with >9 infusions0.91.01.9-1.3-1.31.31.40.00.00.00.01.3-1.31.41.1-0.2
Short access day 1 total inactive lever presses0.30.32.5-0.5-0.0-0.00.30.00.00.00.00.3-0.00.31.0-1.6
Short access day 10 total inactive lever presses2.12.313.41.21.3-1.3-1.30.00.00.00.0-0.81.3-1.3-2.63.7
Short access day 1 total infusions1.51.63.4-1.5-1.41.41.60.00.00.00.01.0-1.51.61.8-1.5
Short access day 10 total infusions2.42.626.5-0.1-0.20.20.10.00.00.00.0-1.4-0.30.0-2.35.1
Short access total infusions0.80.91.7-1.3-1.21.21.30.00.00.00.00.9-1.21.31.0-0.1
Short access day 1 locomotion2.02.118.30.80.4-0.4-0.60.00.00.00.0-0.90.5-0.7-2.44.3
Short access day 10 total locomotion0.40.44.10.0-0.00.00.30.00.00.00.0-0.5-0.10.31.1-2.0
Short access total locomotion0.00.00.3-0.2-0.10.00.10.00.00.00.00.1-0.10.1-0.10.5
Compulsive drug intake4.44.445.1-0.40.0-0.00.30.00.00.00.01.00.00.43.3-6.7
One hour access (0.3 mA shock)1.11.212.20.20.7-0.8-0.30.00.00.00.0-0.00.7-0.31.4-3.5
One hour access (shock baseline)0.40.51.20.81.0-1.0-0.80.00.00.00.0-1.11.0-0.8-0.4-0.4
Number of responses in last shaping day0.30.31.80.30.5-0.5-0.50.00.00.00.00.20.6-0.50.3-1.4
Context. condit. distance diff. score23.929.1292.8-1.3-0.70.81.10.00.00.00.02.7-0.51.38.5-17.1
Locomotion velocity, session 118.219.6205.20.3-0.20.1-0.30.00.00.00.00.80.2-0.5-6.914.3
Locomotion distance, session 157.874.9789.80.7-0.20.1-0.60.00.00.00.0-1.00.2-1.0-13.528.1
Locomotion velocity, session 213.215.5163.8-0.8-1.31.20.90.00.00.00.01.7-0.90.7-5.412.8
Locomotion distance, session 2119.9171.61817.00.9-0.50.3-0.60.00.00.00.0-2.8-0.2-1.2-20.142.6
Locomotion velocity, session 319.322.4207.81.71.3-1.4-1.70.00.00.00.0-2.51.4-1.9-7.914.4
Locomotion distance, session 316.618.0127.62.82.5-2.6-2.70.00.00.00.0-3.52.5-2.9-7.211.3
Stereotopy head waving bouts, day 31.11.310.6-0.9-1.01.00.90.00.00.00.00.3-1.00.8-0.93.3
Stereotopy head waving duration, day 36.98.440.2-2.6-2.52.52.60.00.00.00.03.0-2.42.64.7-6.3
Locomotion velocity, session 711.913.0108.4-1.8-1.61.61.80.00.00.00.02.4-1.61.96.1-10.4
Locomotion distance, session 73.84.840.6-1.2-1.01.01.10.00.00.00.00.9-1.11.23.7-6.4
Stereotopy head waving bouts, day 77.08.077.4-0.8-0.50.50.60.00.00.00.02.2-0.20.74.4-8.8
Stereotopy head waving duration, day 710.312.6124.9-0.7-0.40.50.60.00.00.00.02.6-0.10.85.5-11.2
Locomotion velocity, session 80.81.02.5-1.2-1.11.11.10.00.00.00.01.6-1.01.11.2-1.2
Locomotion distance, session 816.023.8255.7-0.6-1.11.00.60.00.00.00.00.6-0.70.3-7.116.0
Degree of sensitization distance29.229.5200.9-3.8-3.53.53.70.00.00.00.04.4-3.53.99.1-14.2
Degree of sensitization stereotypy3.84.140.9-0.3-0.10.20.20.00.00.00.01.70.20.33.0-6.4
Condit. Reinf. active minus inactive responses0.50.66.20.20.3-0.3-0.20.00.00.00.0-0.60.4-0.21.0-2.5
Condit. Reinf. active-inactive response ratio10.010.8115.80.00.3-0.3-0.00.00.00.00.00.50.20.15.0-10.8
Condit. Reinf. active responses1.92.324.4-0.10.0-0.00.10.00.00.00.0-0.50.20.22.3-4.9
Condit. Reinf. inactive responses1.82.120.40.10.0-0.0-0.10.00.00.00.0-1.40.1-0.2-2.24.5
Incentive salience index mean1.82.118.70.70.8-0.8-0.70.00.00.00.0-1.80.8-0.61.5-4.3
Condit. Reinf. lever presses3.54.847.10.70.9-0.9-0.70.00.00.00.0-1.80.9-0.62.7-6.9
Time in familiar zone, hab. session 11.61.515.50.00.2-0.2-0.00.00.00.00.0-0.8-0.10.01.8-3.9
Time in novel zone, hab. session 13.63.517.0-1.5-1.51.51.50.00.00.00.02.9-1.21.52.9-4.1
Total zone transitions, hab. session 164.991.5949.91.20.4-0.5-1.10.00.00.00.0-3.60.3-1.5-14.930.8
Total locomotion distance, hab. session 126.838.4400.60.60.0-0.1-0.50.00.00.00.0-2.60.0-0.8-9.520.0
Locomotion velocity, hab. session 134.850.0503.01.50.8-0.9-1.30.00.00.00.0-3.50.9-1.6-11.222.4
Time in familiar zone, hab. session 24.95.150.9-1.0-1.31.21.00.00.00.00.01.2-0.90.9-2.77.1
Time in novel zone, hab. session 25.55.658.90.71.0-0.9-0.70.00.00.00.0-0.50.7-0.63.1-7.7
Total zone transitions, hab. session 239.651.2544.20.2-0.50.4-0.10.00.00.00.0-1.6-0.3-0.4-10.823.3
Total locomotion distance, hab. session 220.827.6284.20.70.2-0.3-0.70.00.00.00.0-1.90.4-0.9-8.316.9
Locomotion velocity, hab. session 221.829.5304.30.70.2-0.3-0.70.00.00.00.0-2.10.3-0.9-8.517.4
Novel to familiar place preference ratio0.20.21.50.30.2-0.2-0.30.00.00.00.01.20.5-0.3-0.1-0.5
Novelty place preference0.20.22.10.1-0.0-0.0-0.10.00.00.00.01.50.3-0.1-0.2-0.1
Time in novel zone, NPP test0.40.45.1-0.3-0.50.50.30.00.00.00.02.3-0.00.30.00.2
Total zone transitions, NPP test35.350.7539.90.2-0.60.5-0.10.00.00.00.0-1.0-0.3-0.4-10.823.2
Total locomotion distance, NPP test25.235.0373.6-0.0-0.70.60.10.00.00.00.0-0.4-0.3-0.2-8.919.3
Locomotion velocity, NPP test30.543.6454.70.70.1-0.1-0.60.00.00.00.0-2.10.3-0.9-10.321.3
Pavlov. Cond. lever latency3.94.911.8-2.3-2.32.32.30.00.00.00.03.2-2.32.33.2-3.4
Pavlov. Cond. magazine entry latency9.011.6123.80.71.0-1.0-0.70.00.00.00.0-0.70.9-0.54.7-11.1
Pavlov. Cond. change in total contacts3.84.142.60.60.8-0.8-0.60.00.00.00.0-0.70.8-0.52.5-6.5
Pavlov. Cond. index score5.57.066.31.41.6-1.6-1.40.00.00.00.0-1.81.6-1.32.8-8.1
Pavlov. Cond. latency score3.03.821.21.92.0-2.0-1.80.00.00.00.0-2.52.0-1.80.8-4.6
Pavlov. Cond. lever contacts4.45.219.12.12.0-2.0-2.10.00.00.00.0-3.02.1-2.2-3.54.4
Pavlov. Cond. magazine entry number6.17.777.2-1.2-1.51.41.20.00.00.00.01.4-1.41.1-3.28.8
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.3-0.30.30.30.00.00.00.0-0.1-0.30.30.5-0.6
Pavlov. Cond. lever-magazine prob. diff.8.610.8110.51.21.5-1.5-1.20.00.00.00.0-1.81.5-1.14.0-10.5
Pavlov. Cond. response bias5.56.764.11.41.6-1.6-1.30.00.00.00.0-1.81.5-1.22.8-8.0
Bone: apparent density2.94.951.70.30.4-0.4-0.30.00.00.00.01.20.4-0.23.1-7.2
Bone surface6.311.172.72.42.2-2.2-2.30.00.00.00.0-3.51.9-2.3-5.48.5
Bone volume6.010.280.61.91.7-1.7-1.80.00.00.00.0-2.21.5-1.9-5.49.0
Bone: connectivity density0.81.313.30.50.6-0.6-0.50.00.00.00.00.20.4-0.41.5-3.7
Bone: cortical apparent density0.91.22.6-1.4-1.41.41.30.00.00.00.01.6-1.41.30.51.1
Bone: cortical area1.62.49.51.61.7-1.7-1.60.00.00.00.0-3.11.7-1.6-1.81.4
Bone: cortical porosity18.219.7203.71.31.9-1.9-1.40.00.00.00.0-2.21.4-1.25.7-14.3
Bone: cortical porosity14.715.8167.70.91.4-1.4-1.00.00.00.00.0-1.31.1-0.85.4-13.0
Bone: cortical thickness1.11.814.50.81.0-0.9-0.80.00.00.00.0-1.61.2-0.81.1-3.8
Bone: cortical thickness2.53.021.01.21.5-1.5-1.30.00.00.00.0-2.21.3-1.21.2-4.6
Bone: cortical tissue density1.01.43.9-1.3-1.41.41.30.00.00.00.01.6-1.41.30.02.0
Bone: elastic displacement2.73.031.9-0.3-0.10.10.20.00.00.00.0-0.4-0.10.32.7-5.6
Bone: elastic work0.10.10.9-0.1-0.10.10.10.00.00.00.0-0.90.10.0-0.0-0.2
Bone: endosteal estimation2.96.339.81.71.6-1.6-1.60.00.00.00.0-3.61.1-1.6-3.96.3
Bone: endosteal perimeter0.61.24.81.21.2-1.2-1.20.00.00.00.0-2.21.1-1.2-1.10.9
Bone: final force7.812.794.02.22.0-2.0-2.10.00.00.00.0-3.21.9-2.3-6.09.7
Bone: final moment6.811.275.12.22.0-2.1-2.10.00.00.00.0-3.81.9-2.2-5.58.7
Bone: marrow area2.55.532.81.61.6-1.6-1.50.00.00.00.0-3.51.1-1.6-3.65.7
Bone: maximum diameter0.81.54.51.31.2-1.2-1.20.00.00.00.0-2.11.2-1.2-1.61.8
Bone: maximum force8.614.9104.92.52.3-2.3-2.40.00.00.00.0-3.72.2-2.6-6.410.2
Bone: maximum moment6.811.971.72.42.3-2.4-2.40.00.00.00.0-4.22.1-2.5-5.68.5
Bone: minimum diameter10.619.6160.22.11.8-1.8-2.00.00.00.00.0-4.51.8-2.1-7.212.7
Bone: periosteal estimation2.75.620.42.02.0-2.0-2.00.00.00.00.0-4.31.7-2.0-3.44.5
Bone: periosteal perimeter1.72.914.51.31.2-1.2-1.30.00.00.00.0-2.61.2-1.3-2.63.8
Bone: post-yield work14.820.2169.12.32.0-2.1-2.30.00.00.00.0-3.01.9-2.4-7.513.0
Bone: stiffness15.925.2216.32.42.0-2.1-2.30.00.00.00.0-3.41.9-2.5-8.314.7
Bone: tissue strength12.612.2131.7-0.4-0.80.80.50.00.00.00.00.3-0.50.3-5.011.5
Bone: trabecular number6.29.699.6-0.20.1-0.00.20.00.00.00.01.5-0.10.34.8-10.0
Bone: trabecular spacing0.81.17.3-1.0-1.01.01.00.00.00.00.0-0.6-1.10.9-0.52.7
Bone: trabecular thickness2.42.916.71.51.3-1.4-1.50.00.00.00.0-0.81.3-1.5-2.94.1
Bone: trabecular tissue density7.09.793.3-1.1-0.70.71.00.00.00.00.00.7-1.01.15.2-9.7
Breakpoint value in progressive ratio session0.10.10.2-0.3-0.30.30.30.00.00.00.00.3-0.30.30.4-0.4
Distance traveled before self-admin2.62.713.5-1.4-1.31.31.50.00.00.00.01.7-1.31.52.7-3.7
Distance traveled after self-admin0.00.10.2-0.3-0.30.30.30.00.00.00.00.2-0.30.2-0.00.5
Delta time in closed arm before/after self-admin0.80.81.5-1.2-1.21.21.20.00.00.00.01.1-1.21.20.70.2
Delta time in open arm before/after self-admin3.83.638.30.40.7-0.7-0.40.00.00.00.00.20.7-0.32.6-6.2
Diff in mean of infusions in LGA sessions0.50.54.70.20.2-0.2-0.30.00.00.00.0-0.40.2-0.3-1.22.2
Extinction: sum of active levers before priming1.21.212.30.2-0.00.0-0.10.00.00.00.0-0.5-0.0-0.2-1.73.5
Active lever presses in extinction session 60.90.98.8-0.5-0.60.60.50.00.00.00.00.2-0.60.4-1.03.0
Delta distance traveled before/after self-admin2.32.412.11.31.2-1.2-1.40.00.00.00.0-1.61.2-1.4-2.63.5
Delta ambulatory time before/after self-admin1.21.35.11.11.0-1.0-1.10.00.00.00.0-1.31.0-1.1-1.82.3
Time in closed arm before self-admin8.29.489.01.00.5-0.5-1.00.00.00.00.0-1.90.5-1.1-5.09.4
Time in closed arm after self-admin4.24.441.80.70.4-0.4-0.70.00.00.00.0-1.30.4-0.8-3.46.5
Time in open arm before self-admin0.00.00.0-0.2-0.20.20.20.00.00.00.00.2-0.20.20.2-0.1
Time in open arm after self-admin2.93.234.40.30.6-0.6-0.30.00.00.00.00.30.6-0.22.5-5.9
Sum of active levers in priming session hrs 5-60.20.20.90.40.4-0.4-0.40.00.00.00.0-0.50.4-0.4-0.71.0
Time to tail flick, vehicle, before self-admin0.30.32.90.20.1-0.1-0.20.00.00.00.0-0.40.1-0.2-0.91.7
Time to tail flick, vehicle, after self-admin0.50.52.5-0.7-0.60.60.60.00.00.00.00.8-0.60.71.2-1.6
Time to tail flick, test, before self-admin0.10.10.9-0.2-0.30.30.20.00.00.00.00.1-0.30.2-0.30.9
Time to tail flick, test, after self-admin0.60.61.3-1.0-1.11.11.00.00.00.00.00.8-1.11.00.21.1
Delta time to tail flick, vehicle, before/after SA0.90.97.3-0.5-0.40.40.50.00.00.00.00.8-0.40.51.6-2.7
Delta time to tail flick, test, before/after SA2.11.917.9-0.7-1.01.00.70.00.00.00.00.3-1.00.7-1.44.2
Ambulatory time before self-admin1.11.15.9-0.9-1.21.21.20.00.00.00.01.0-1.21.1-0.32.4
Ambulatory time after self-admin0.00.00.4-0.1-0.10.10.10.00.00.00.00.0-0.10.1-0.20.6
Total heroin consumption0.70.81.6-1.2-1.01.01.10.00.00.00.01.3-1.01.11.1-0.7
Area under the delay curve0.60.71.7-0.4-1.31.31.00.00.00.00.00.5-1.31.01.0-0.6
Delay disc. indifference point, 0s delay0.60.61.5-0.6-1.21.20.90.00.00.00.00.7-1.20.90.9-0.4
Delay disc. indifference point, 16s delay0.10.10.20.0-0.40.40.30.00.00.00.00.0-0.50.30.3-0.2
Delay disc. indifference point, 2s delay1.01.12.6-0.8-1.51.61.20.00.00.00.00.9-1.61.21.2-0.8
Delay disc. indifference point, 24s delay1.31.22.9-0.9-1.61.71.30.00.00.00.00.9-1.71.31.3-0.8
Delay disc. indifference point, 4s delay0.40.51.2-0.4-1.01.10.70.00.00.00.00.5-1.10.70.8-0.6
Delay disc. indifference point, 8s delay0.10.10.20.2-0.40.40.30.00.00.00.0-0.2-0.40.30.3-0.2
Delay discount exponential model param0.60.71.70.51.3-1.3-0.90.00.00.00.0-0.51.3-0.9-1.00.7
Delay discount hyperbolic model param0.60.61.60.41.2-1.3-0.90.00.00.00.0-0.51.3-0.9-0.90.6
Fecal boli incidents, locomotor time 11.41.512.80.50.5-0.5-0.60.00.00.00.0-0.80.5-0.7-2.23.6
Change in fecal boli incidents, locomotor task1.01.08.4-0.4-0.30.30.40.00.00.00.00.6-0.30.51.7-2.9
Time >=10cm from walls, locomotor time 12.42.419.61.31.3-1.3-1.10.00.00.00.0-0.91.3-1.01.5-4.4
Bouts of movement, locomotor time 10.20.21.8-0.0-0.10.10.00.00.00.00.0-0.0-0.10.0-0.61.3
Total resting periods, locomotor time 10.10.10.80.10.0-0.0-0.10.00.00.00.0-0.10.0-0.1-0.50.9
Rest time, locomotor task time 12.22.44.21.91.9-1.9-1.90.00.00.00.0-1.91.8-1.9-2.11.6
Distance moved, locomotor task time 10.91.03.6-0.9-0.90.91.00.00.00.00.01.0-0.91.01.6-1.9
Vertical activity count, locomotor time 11.31.44.5-1.2-1.21.21.20.00.00.00.01.3-1.21.21.9-2.1
Time >=10cm from walls, locomotor time 23.63.828.9-0.9-1.01.01.20.00.00.00.01.4-1.01.33.5-5.4
Bouts of movement, locomotor time 23.03.25.7-2.4-2.42.42.20.00.00.00.02.1-2.42.20.42.2
Total resting periods, locomotor time 22.52.76.4-2.1-2.12.12.00.00.00.00.01.8-2.11.90.12.5
Rest time, locomotor task time 21.72.010.31.11.1-1.1-1.20.00.00.00.0-1.31.1-1.3-2.43.2
Distance moved, locomotor task time 21.72.015.2-0.7-0.70.70.90.00.00.00.01.0-0.70.92.5-3.9
Vertical activity count, locomotor time 20.70.84.1-0.7-0.70.70.70.00.00.00.00.8-0.70.81.5-2.0
Weight adjusted by age2.83.128.0-0.8-0.40.40.70.00.00.00.00.6-0.60.83.1-5.3
Seeking ratio, delayed vs. immediate footshock0.60.76.10.20.2-0.2-0.20.00.00.00.0-0.50.2-0.3-1.42.5
Locomotion in novel chamber1.21.412.6-0.7-0.30.30.50.00.00.00.00.6-0.40.62.0-3.6
Locomotion in novel chamber post-restriction1.11.32.5-1.5-1.61.61.40.00.00.00.01.4-1.51.41.0-0.1
Progressive ratio0.70.81.5-1.2-1.21.21.20.00.00.00.01.2-1.21.20.8-0.0
Food seeking constrained by brief footshock0.20.22.2-0.20.1-0.10.10.00.00.00.00.10.00.10.7-1.5
Seeking ratio, punishment vs. effort0.70.91.61.21.2-1.2-1.20.00.00.00.0-1.31.2-1.2-0.90.2
Run reversals in cocaine runway, females1.61.63.3-1.5-1.81.81.60.00.00.00.01.2-1.81.60.90.7
Run reversals in cocaine runway, males4.13.938.0-0.6-0.30.30.60.00.00.00.00.7-0.40.73.3-6.2
Latency to leave start box in cocaine runway1.82.020.50.30.0-0.1-0.20.00.00.00.0-0.30.1-0.3-2.34.5
Latency to leave start box in cocaine runway, F0.60.74.0-0.8-0.90.90.80.00.00.00.00.7-0.90.7-0.52.0
Latency to leave start box in cocaine runway, M0.90.95.40.80.7-0.8-0.70.00.00.00.0-0.70.7-0.8-1.52.3
Cd content in liver22.424.6262.41.01.6-1.5-1.10.00.00.00.0-1.51.3-0.86.8-16.2
Co content in liver13.415.7168.41.01.4-1.3-1.00.00.00.00.00.61.4-0.95.2-13.0
Cu content in liver0.50.61.31.11.1-1.1-1.10.00.00.00.0-0.21.0-1.1-0.7-0.2
Fe content in liver1.01.212.30.10.1-0.1-0.10.00.00.00.00.70.3-0.01.5-3.5
K content in liver13.513.587.32.72.6-2.6-2.70.00.00.00.0-3.12.2-2.8-6.29.3
Mg content in liver1.41.42.71.61.6-1.6-1.60.00.00.00.0-0.11.4-1.6-1.60.8
Mn content in liver20.623.7237.41.10.7-0.8-1.00.00.00.00.0-2.00.5-1.2-7.815.4
Na content in liver0.10.10.7-0.3-0.30.30.30.00.00.00.00.0-0.50.3-0.20.8
Rb content in liver3.13.839.30.20.3-0.3-0.20.00.00.00.01.70.2-0.12.7-6.3
Se content in liver6.57.956.82.62.8-2.8-2.60.00.00.00.0-0.62.7-2.51.6-7.5
Sr content in liver2.22.05.11.61.6-1.6-1.60.00.00.00.0-1.41.3-1.6-2.22.3
Zn content in liver4.55.050.60.91.0-1.0-0.90.00.00.00.01.41.1-0.82.6-7.1