Best TWAS P=2.335955e-07 · Best GWAS P=3.321121e-06 conditioned to 0.4153099
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | LHb | Galnt16 | gene expression | ENSRNOG00000004589 | 0.3 | 0.16 | enet | 6 | 0.25 | 1.4e-06 | -3.9 | 5.2 | 2.3e-07 | 0.81 | 0.4 | 0.43 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.