Best TWAS P = 1.17e-08 · Best GWAS P= 5.83e-09 conditioned to 1.05e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Aox3 | alternative TSS | XM_039084037.2 | 0.04 | 15 | 0.04 | 2.3e-05 | 5.7 | 1.23e-08 | 0.4 | FALSE |
| Adipose | Aox3 | alternative TSS | XM_039084037.2 | 0.05 | 15 | 0.05 | 1.8e-06 | 5.6 | 2.08e-08 | 0.44 | FALSE |
| Adipose | Cflar | alternative TSS | XM_063266583.1 | 0.06 | 1 | 0.04 | 2.8e-05 | 5.47 | 4.50e-08 | 0.53 | FALSE |
| Adipose | Cflar | alternative TSS | XM_063266583.1 | 0.21 | 113 | 0.16 | 3.3e-17 | 5.33 | 9.70e-08 | 0.91 | FALSE |
| Adipose | Cflar | isoform ratio | NM_001033864.4 | 0.03 | 1 | 0.02 | 1.8e-03 | 5.42 | 5.80e-08 | 0.13 | FALSE |
| Adipose | Cflar | isoform ratio | XR_010054556.1 | 0.03 | 1 | 0.02 | 3.5e-03 | -5.44 | 5.27e-08 | 0.12 | FALSE |
| BLA | Kctd18 | isoform ratio | XM_039083313.2 | 0.06 | 1 | 0.04 | 5.4e-03 | 5.5 | 3.85e-08 | 0.05 | FALSE |
| BLA | Kctd18 | intron excision ratio | chr9_67009283_67010030 | 0.09 | 2588 | 0.07 | 2.2e-04 | 5.53 | 3.23e-08 | 0.53 | FALSE |
| Brain | Cflar | alternative TSS | XM_063266583.1 | 0.07 | 2374 | 0.03 | 1.3e-03 | 5.7 | 1.17e-08 | 0.7 | TRUE |
| Brain | Spats2l | alternative TSS | XM_006244992.4 | 0.04 | 1 | 0.04 | 2.1e-04 | -5.7 | 1.21e-08 | 0.15 | FALSE |
| Brain | Spats2l | alternative TSS | XM_006244992.4 | 0.03 | 1 | 0.02 | 2.8e-03 | -5.7 | 1.21e-08 | 0.06 | FALSE |
| Brain | Aox4 | gene expression | Aox4 | 0.04 | 1 | 0.04 | 1.0e-04 | 5.4 | 6.81e-08 | 0.07 | FALSE |
| Brain | Nif3l1 | gene expression | Nif3l1 | 0.07 | 2347 | 0.02 | 2.2e-03 | 5.57 | 2.55e-08 | 0.75 | FALSE |
| Brain | Spats2l | isoform ratio | XM_006244992.4 | 0.03 | 1 | 0.03 | 1.1e-03 | -5.7 | 1.21e-08 | 0.06 | FALSE |
| Brain | Aox1 | intron excision ratio | chr9_67097612_67101310 | 0.04 | 2577 | 0.03 | 1.7e-03 | -5.31 | 1.10e-07 | 0.45 | FALSE |
| Liver | Kctd18 | gene expression | Kctd18 | 0.05 | 2588 | 0.02 | 3.7e-03 | 5.43 | 5.67e-08 | 0.56 | FALSE |
| Liver | Spats2l | gene expression | Spats2l | 0.07 | 2517 | 0.06 | 5.0e-07 | 5.42 | 5.86e-08 | 0.08 | FALSE |
| Liver | Kctd18 | intron excision ratio | chr9_67028839_67031148 | 0.02 | 1 | 0.02 | 1.0e-03 | -5.44 | 5.27e-08 | 0.03 | FALSE |
| Liver | Flacc1 | mRNA stability | Flacc1 | 0.04 | 1 | 0.03 | 1.8e-04 | 5.34 | 9.06e-08 | 0.3 | FALSE |
| NAcc | Maip1 | gene expression | Maip1 | 0.04 | 1 | 0.02 | 3.4e-04 | 5.63 | 1.80e-08 | 0.21 | FALSE |
| PL | Cflar | alternative TSS | XM_063266583.1 | 0.09 | 2374 | 0.07 | 9.5e-08 | 5.41 | 6.16e-08 | 0.58 | FALSE |
| PL | Spats2l | isoform ratio | XM_006244992.4 | 0.02 | 2517 | 0.02 | 3.6e-03 | -5.61 | 2.01e-08 | 0.37 | FALSE |
| PL | Kctd18 | intron excision ratio | chr9_67009283_67011591 | 0.03 | 2588 | 0.01 | 8.8e-03 | -5.69 | 1.24e-08 | 0.56 | FALSE |
| pVTA | Kctd18 | isoform ratio | XM_039083314.2 | 0.04 | 14 | 0.03 | 1.8e-03 | 5.53 | 3.14e-08 | 0.27 | FALSE |