Hub : Genes

Kctd18

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000027091 0.08 0.05 1.6e-05 0.03 0.04 0.04 0.04 9.2e-05 2.9e-05 1.9e-05 5.6e-05
2 BLA intron excision ratio chr9:59515068:59515815 0.08 0.05 1.5e-03 0.06 0.06 0.05 0.05 3.9e-04 5.1e-04 1.6e-03 1.3e-03
3 BLA intron excision ratio chr9:59515068:59516751 0.11 0.06 1.0e-04 0.08 0.07 0.08 0.08 4.5e-05 1.4e-04 5.4e-05 3.9e-05
4 Brain intron excision ratio chr9:59515068:59515815 0.13 0.07 2.4e-08 0.1 0.09 0.08 0.1 2.4e-09 1.2e-08 1.2e-07 1.8e-09
5 Brain intron excision ratio chr9:59515068:59516751 0.12 0.06 7.9e-08 0.09 0.09 0.09 0.09 6.5e-09 4.8e-09 9.5e-09 1.1e-08
6 LHb intron excision ratio chr9:59510430:59512513 0.14 0.09 6.2e-03 0.06 0.06 0.04 0.11 1.7e-02 1.4e-02 4.0e-02 1.8e-03
7 LHb intron excision ratio chr9:59510430:59512535 0.13 0.09 9.2e-03 0.1 0.06 0.03 0.09 2.7e-03 1.5e-02 5.9e-02 3.1e-03
8 Liver gene expression ENSRNOG00000027091 0.04 0.03 5.5e-04 0.01 0.02 0.02 0.02 1.0e-02 3.1e-03 1.0e-03 4.4e-03
9 Liver intron excision ratio chr9:59515068:59515815 0.07 0.04 4.5e-05 0.03 0.03 0.03 0.02 6.1e-04 6.0e-04 6.4e-04 2.2e-03
10 Liver mRNA stability ENSRNOG00000027091 0.1 0.06 1.2e-07 0.05 0.06 0.06 0.05 1.6e-06 3.0e-07 7.4e-07 2.2e-06
11 NAcc intron excision ratio chr9:59515068:59515815 0.1 0.06 4.8e-06 0.08 0.07 0.06 0.08 1.5e-06 6.5e-06 1.5e-05 1.0e-06
12 NAcc intron excision ratio chr9:59515068:59516751 0.04 0.03 2.4e-03 0.03 0.04 0.02 0.03 3.3e-03 1.2e-03 1.9e-02 1.8e-03
13 NAcc intron excision ratio chr9:59515867:59516751 0.05 0.03 3.4e-03 0.03 0.03 0.03 0.02 2.9e-03 5.6e-03 3.2e-03 6.5e-03
14 PL intron excision ratio chr9:59515068:59515815 0.05 0.03 7.8e-04 0.02 0.05 0.04 0.03 7.8e-03 2.1e-04 6.3e-04 1.7e-03
15 PL intron excision ratio chr9:59515068:59516751 0.06 0.04 8.4e-04 0.02 0.04 0.03 0.03 5.6e-03 6.7e-04 1.5e-03 3.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail4.715.323.4-4.8-3.74.2-4.14.03.9-4.0-4.3-3.1-2.1-4.13.5-4.2-3.84.2
BMI without tail2.96.010.6-2.6-1.42.5-2.72.92.0-2.8-2.2-3.3-2.8-2.31.3-2.9-2.22.2
Body weight0.10.20.60.10.8-0.50.3-0.0-0.5-0.00.4-0.6-0.70.4-0.70.00.4-0.4
Epididymis fat weight0.61.44.61.11.6-1.01.1-0.4-2.10.71.5-0.5-0.11.2-1.31.00.5-1.6
Glucose1.21.82.6-1.2-1.51.3-1.41.61.1-1.2-1.6-1.0-0.3-1.51.5-1.5-1.61.4
Heart weight0.20.21.3-0.60.60.0-0.1-0.20.5-0.30.1-0.4-1.10.1-0.7-0.00.60.0
Left kidney weight0.00.00.1-0.10.2-0.30.2-0.2-0.0-0.10.10.0-0.10.1-0.20.10.2-0.1
Right kidney weight0.00.10.6-0.80.6-0.10.1-0.2-0.20.10.3-0.3-0.60.3-0.60.10.4-0.2
Tail length6.218.831.65.64.9-4.94.4-3.9-4.63.94.92.11.14.7-4.44.44.2-4.9
Length with tail6.524.032.65.75.4-5.55.1-4.7-5.24.65.52.71.55.4-5.05.04.9-5.5
Length without tail2.55.57.12.32.0-2.62.5-2.7-2.32.52.42.31.82.4-1.92.62.3-2.4
Liver weight, left0.30.41.00.30.8-0.40.10.2-0.90.20.6-1.0-0.90.8-0.8-0.20.3-0.7
Liver weight, right1.72.85.61.62.0-1.61.3-1.8-1.01.61.80.7-0.52.1-2.31.22.4-1.8
Parametrial fat weight0.10.10.5-0.7-0.20.0-0.10.4-0.3-0.3-0.1-0.5-0.1-0.10.2-0.3-0.40.0
Retroperitoneal fat weight0.10.51.6-0.6-0.20.8-0.81.00.1-0.8-0.4-1.3-0.9-0.50.2-0.8-0.70.4
Intraocular pressure2.53.56.2-0.5-2.51.9-1.61.72.3-1.6-2.2-0.30.4-2.52.5-1.6-2.02.4
Extensor digitorum longus weight1.66.49.4-2.7-2.62.6-2.43.01.9-2.5-2.8-2.1-0.8-2.62.7-2.8-3.12.6
Soleus weight0.20.72.3-1.00.20.7-0.90.90.5-1.0-0.6-1.4-1.5-0.3-0.1-1.0-0.40.5
Tibialis anterior weight0.00.10.2-0.1-0.40.2-0.20.30.1-0.2-0.5-0.10.2-0.20.5-0.3-0.50.3
Tibia length4.211.815.73.23.7-3.63.3-3.5-3.73.43.92.31.33.8-3.53.73.5-4.0
Number of licking bursts0.30.40.80.80.2-0.60.5-0.8-0.20.70.40.90.50.7-0.40.50.8-0.5
Food consumed during 24 hour testing period1.72.03.5-1.5-1.81.4-1.41.31.4-1.1-1.5-0.5-0.1-1.51.6-1.9-1.41.6
Times rat made contact with spout1.72.03.2-1.5-1.81.5-1.51.51.2-1.2-1.5-1.0-0.4-1.31.5-1.4-1.61.5
Mean time between licks in bursts0.60.82.4-0.8-0.60.9-0.81.4-0.2-0.9-0.6-1.3-0.3-0.90.9-0.3-1.60.6
Mean num. licks in bursts1.92.33.6-1.8-1.51.6-1.51.91.0-1.5-1.4-1.4-0.6-1.71.5-1.2-1.91.5
Std. dev. time between licks in bursts0.81.01.6-0.5-1.21.0-1.01.10.9-1.0-1.2-0.6-0.1-1.21.2-0.4-1.21.2
Water consumed over 24 hours3.84.47.1-1.8-2.72.2-2.01.82.6-1.9-2.5-0.7-0.3-2.42.4-2.2-1.92.6
Indifference point 0 sec0.10.20.50.4-0.70.10.00.00.4-0.1-0.40.50.7-0.60.70.0-0.30.5
Indifference point AUC1.21.52.81.71.0-1.21.3-1.4-0.91.31.11.41.11.0-0.71.51.1-1.1
Indifference point function ln k0.40.61.9-1.4-0.40.9-0.80.80.5-0.9-0.5-1.0-0.8-0.60.3-0.8-0.60.7
Indifference point function log k0.40.61.9-1.4-0.40.9-0.80.80.5-0.9-0.5-1.0-0.8-0.60.3-0.8-0.60.7
Delay discounting total patch changes 0 sec0.20.30.70.6-0.80.2-0.10.00.8-0.3-0.60.70.8-0.80.90.0-0.40.7
Delay discounting total patch changes 12 sec0.60.83.21.8-0.0-0.81.0-0.8-0.30.70.21.41.50.10.31.00.2-0.3
Delay discounting total patch changes 18 sec0.81.02.60.7-1.60.4-0.20.21.0-0.2-1.01.11.6-1.21.6-0.0-1.01.0
Delay discounting total patch changes 24 sec0.70.92.11.10.5-0.91.2-1.2-0.51.10.61.41.20.6-0.31.20.8-0.7
Delay discounting total patch changes 6 sec0.10.21.51.20.00.3-0.10.10.8-0.3-0.50.0-0.3-0.50.2-0.20.10.4
Delay discounting time to switch 0 sec0.50.71.1-0.9-0.80.6-0.70.91.0-1.0-1.1-0.8-0.8-0.80.7-1.0-0.70.9
Delay discounting water rate 0 sec0.30.51.00.80.8-0.50.5-0.7-0.90.71.00.50.40.7-0.70.90.6-0.8
Delay discounting water rate 12 sec0.60.82.8-1.2-0.01.1-1.10.70.9-0.8-0.6-1.3-1.7-0.5-0.1-1.1-0.10.7
Delay discounting water rate 18 sec0.20.30.70.50.3-0.20.4-0.80.10.70.40.80.20.5-0.50.40.8-0.3
Delay discounting water rate 24 sec0.40.62.4-1.50.20.7-0.80.50.3-0.6-0.2-1.2-1.50.1-0.4-0.90.00.2
Delay discounting water rate 6 sec0.20.30.7-0.3-0.10.8-0.70.50.4-0.6-0.4-0.7-0.7-0.30.1-0.6-0.30.4
Locomotor activity0.40.61.0-0.4-0.91.0-0.91.00.5-0.6-0.8-0.6-0.1-0.90.9-0.9-1.00.8
Locomotor testing distance1.42.43.3-1.1-1.81.7-1.61.61.7-1.3-1.8-0.9-0.5-1.71.6-1.8-1.51.8
Locomotor testing rearing0.20.20.9-1.0-0.70.7-0.50.50.2-0.1-0.4-0.4-0.2-0.10.4-0.7-0.40.4
Light reinforcement 15.39.818.3-4.3-3.33.3-3.13.32.6-3.0-3.4-2.3-1.2-3.23.0-3.4-3.33.2
Light reinforcement 20.10.10.6-0.10.30.1-0.20.4-0.0-0.4-0.2-0.8-0.7-0.3-0.1-0.2-0.20.0
Reaction time number correct0.60.91.7-0.8-0.91.1-1.30.81.3-0.8-1.1-0.6-0.8-0.80.6-1.3-0.51.1
Reaction time mean minus median0.00.00.2-0.5-0.00.2-0.1-0.1-0.00.10.10.0-0.00.2-0.10.00.1-0.1
Reaction time mean minus median AUC0.10.10.4-0.1-0.40.10.1-0.30.40.2-0.20.70.50.20.2-0.00.20.1
Reaction time num false alarms1.82.54.1-1.6-1.51.7-1.61.90.9-1.6-1.6-1.4-0.5-1.91.7-1.6-2.01.6
Reaction time num false alarms AUC2.02.84.5-1.5-1.61.7-1.72.11.0-1.6-1.7-1.5-0.6-2.01.7-1.7-2.11.7
Reaction time trials correct on left0.60.91.7-0.8-0.91.1-1.30.81.3-0.8-1.1-0.6-0.8-0.80.6-1.3-0.51.1
Reaction time trials on left0.60.91.6-0.9-0.81.0-1.20.81.3-0.8-1.1-0.6-0.8-0.80.6-1.3-0.51.0
Reaction time mean2.53.45.41.61.7-2.02.2-1.7-2.31.62.21.41.42.0-1.42.31.3-2.1
Reaction time mean AUC1.92.64.31.21.4-1.71.9-1.5-2.11.41.91.31.41.7-1.22.01.1-1.8
Median of all reaction times4.15.68.82.22.1-2.62.8-2.2-3.02.02.81.92.02.4-1.83.01.6-2.6
Reaction time omissions0.20.20.6-0.80.4-0.40.5-0.2-0.80.20.40.00.10.7-0.40.20.2-0.6
Reaction time false alarm rate0.60.92.2-0.9-0.80.9-0.81.30.1-0.9-0.8-1.0-0.1-1.21.1-0.8-1.50.8
Reaction time premature initiation rate0.20.31.50.7-0.3-0.30.5-0.80.60.3-0.11.20.80.10.20.40.50.1
Reaction time premature initiations0.30.41.8-0.0-0.80.5-0.4-0.11.4-0.3-0.90.60.2-0.40.6-0.50.10.8
Std. dev. reaction times0.60.91.80.41.0-0.91.0-1.0-1.00.91.10.50.31.3-1.00.91.0-1.1
Reaction time trials completed0.60.91.6-0.9-0.81.0-1.20.81.3-0.8-1.1-0.6-0.8-0.80.6-1.3-0.51.0
Reaction time trials AUC0.50.71.3-0.7-0.80.9-1.10.71.1-0.6-1.0-0.5-0.7-0.70.6-1.1-0.40.9
Social response proportion0.70.71.60.51.2-0.70.5-0.6-0.90.91.2-0.1-0.51.0-1.30.51.0-1.0
Social responses1.11.42.80.81.2-1.01.0-1.0-1.71.61.60.50.31.5-1.30.91.1-1.5
Social time0.50.61.00.60.8-0.80.8-0.8-0.80.81.00.60.41.0-0.80.90.8-0.9
Conditioned locomotion0.40.51.40.31.0-0.40.3-0.2-1.20.71.1-0.5-0.40.7-1.00.50.4-1.0
Cocaine response after cond. corrected1.11.22.30.41.5-1.21.0-0.9-1.40.81.5-0.0-0.41.3-1.51.01.1-1.4
Cocaine response after cond. not corrected1.92.14.20.81.8-1.51.3-1.4-1.21.21.70.3-0.61.8-2.11.11.9-1.6
Cocaine response before conditioning0.30.41.50.50.1-0.30.2-0.90.70.80.00.9-0.10.6-0.5-0.01.2-0.1
Saline control response0.10.20.6-0.60.10.2-0.30.10.6-0.3-0.3-0.4-0.8-0.1-0.2-0.50.20.4
Condit. Reinf. active minus inactive responses3.03.75.92.32.0-2.01.9-2.2-1.42.02.01.40.42.2-2.11.72.4-2.0
Condit. Reinf. active-inactive response ratio3.03.16.22.51.4-1.91.9-2.2-0.81.81.52.11.21.6-1.31.82.1-1.4
Condit. Reinf. active responses2.43.45.11.91.8-1.91.7-2.1-1.62.22.01.40.62.2-1.91.62.3-2.0
Condit. Reinf. inactive responses0.10.20.5-0.40.3-0.20.1-0.2-0.70.60.5-0.0-0.00.7-0.50.10.3-0.6
Condit. Reinf. lever presses0.50.63.01.0-0.4-0.30.5-1.00.30.9-0.01.71.40.30.30.60.6-0.1
Condit. Reinf. lever reinforcers received2.43.45.22.01.7-1.81.7-2.1-1.52.21.91.60.72.2-1.91.62.3-1.9
Pavlov. Cond. lever latency0.71.04.5-1.10.40.7-0.91.3-0.1-1.1-0.2-2.1-1.9-0.5-0.2-0.9-0.70.2
Pavlov. Cond. magazine entry latency0.60.63.01.2-0.5-0.40.6-0.7-0.10.80.01.61.70.00.60.70.1-0.1
Pavlov. Cond. change in total contacts3.95.510.13.01.2-2.32.6-2.7-1.82.62.03.22.91.9-1.02.81.9-2.0
Pavlov. Cond. index score1.72.26.72.00.0-1.31.5-1.7-0.71.70.82.62.50.80.01.60.9-0.9
Pavlov. Cond. latency score1.62.16.42.00.0-1.21.4-1.6-0.71.70.82.52.40.80.01.60.9-0.8
Pavlov. Cond. lever contacts1.21.65.91.5-0.1-1.01.3-1.6-0.31.40.62.42.10.8-0.01.31.0-0.6
Pavlov. Cond. magazine entry number0.91.23.4-1.6-0.00.9-1.11.10.6-1.3-0.6-1.8-1.8-0.6-0.1-1.2-0.60.7
Pavlov. Cond. intertrial magazine entries0.81.13.9-1.20.11.0-1.20.90.9-1.1-0.6-1.6-2.0-0.5-0.2-1.2-0.20.7
Pavlov. Cond. lever-magazine prob. diff.2.02.57.12.20.2-1.41.6-1.8-0.91.91.02.72.61.0-0.11.81.0-1.0
Pavlov. Cond. response bias1.01.44.81.5-0.0-1.01.2-1.4-0.41.40.62.22.00.7-0.01.20.9-0.6
Conditioned reinforcement - actives0.10.10.30.20.2-0.40.4-0.2-0.3-0.10.20.30.60.10.1-0.1-0.1-0.3
Conditioned reinforcement - inactives2.02.24.41.40.9-1.71.7-1.4-1.81.51.41.72.01.3-0.52.10.7-1.4
Conditioned locomotion0.91.13.4-1.8-1.01.0-1.21.00.8-0.9-1.1-0.9-0.6-0.70.8-1.4-1.00.8
Intermittent access intake day 1-15 change0.90.92.9-1.0-0.80.8-0.80.51.7-1.0-1.2-0.4-0.8-0.90.6-1.1-0.31.2
Intermittent access intake escalation0.50.42.2-0.7-0.60.4-0.50.11.5-0.6-0.90.1-0.5-0.60.4-0.80.10.9
Intermittent access intake escalation 20.10.10.80.10.2-0.1-0.1-0.20.9-0.1-0.3-0.1-0.8-0.1-0.30.00.60.3
Intermitt. access day 1 inactive lever presses0.70.71.9-0.3-1.40.4-0.30.50.5-0.4-0.90.51.2-0.81.4-1.0-1.00.8
Intermitt. access day 15 inactive lever presses0.10.10.2-0.20.1-0.40.2-0.4-0.00.40.10.50.30.3-0.10.20.3-0.2
Intermitt. access escalation Index0.20.20.60.1-0.10.10.00.5-0.8-0.20.1-0.20.6-0.40.40.1-0.8-0.1
Intermittent access day 1 total infusions0.20.21.10.20.1-0.60.6-0.3-0.60.10.20.61.00.10.20.5-0.1-0.3
Intermittent access day 15 total infusions0.20.20.80.1-0.3-0.30.3-0.30.5-0.3-0.40.80.9-0.40.6-0.2-0.10.4
Intermittent access terminal intake (last 3 days)0.30.30.8-0.4-0.70.1-0.0-0.20.8-0.2-0.60.90.8-0.50.8-0.4-0.20.6
Intermittent access total infusions0.20.21.4-0.1-0.3-0.30.3-0.30.00.1-0.20.91.2-0.20.60.2-0.20.1
Intermittent access day 1 locomotion0.50.53.8-0.5-0.5-0.50.5-0.5-0.40.3-0.11.41.9-0.10.80.1-0.4-0.1
Intermittent access day 15 total locomotion0.20.21.3-0.0-0.2-0.30.5-0.50.00.4-0.11.11.10.10.30.40.1-0.0
Intermittent access total locomotion0.20.21.1-0.9-0.5-0.20.1-0.1-0.1-0.0-0.30.61.0-0.30.7-0.3-0.50.2
Intermittent access standard deviation0.40.40.90.3-0.80.10.0-0.10.9-0.0-0.70.90.9-0.80.9-0.1-0.30.8
Cocaine induced anxiety0.30.40.8-0.9-0.50.7-0.70.80.4-0.6-0.6-0.9-0.7-0.50.4-0.4-0.60.5
Post-drug Anxiety0.40.51.60.40.00.8-0.70.80.7-0.9-0.4-1.1-1.3-0.6-0.0-0.3-0.30.6
Baseline Anxiety0.90.92.91.71.0-0.80.9-1.0-0.70.81.10.70.40.8-0.91.01.0-0.9
Lifetime Intake0.20.20.7-0.8-0.60.1-0.10.10.2-0.2-0.50.50.9-0.50.8-0.1-0.50.4
Incentive Sensitization - Responses0.70.71.31.10.7-0.91.0-0.7-1.10.50.90.70.90.7-0.40.90.4-0.8
Incentive Sensitization - Breakpoint0.60.61.31.10.6-0.81.0-0.6-1.10.40.80.60.90.7-0.30.90.3-0.8
Progressive ratio test 1 active lever presses0.40.42.3-0.4-0.7-0.20.3-0.2-0.00.1-0.31.11.5-0.40.9-0.2-0.50.3
Progressive ratio test 1 breakpoint0.30.32.0-0.2-0.6-0.20.3-0.30.20.1-0.41.11.4-0.40.8-0.2-0.30.3
Progressive ratio test 1 inactive lever presses3.33.56.8-1.7-2.61.6-1.41.71.4-1.7-2.2-0.31.0-2.22.6-1.5-2.42.0
Progressive ratio test 2 active lever presses0.30.32.10.2-0.1-0.50.7-0.5-0.30.10.11.11.4-0.00.40.4-0.1-0.1
Progressive ratio test 2 breakpoint0.30.32.20.1-0.5-0.20.4-0.30.1-0.2-0.21.11.5-0.40.80.3-0.30.3
Progressive ratio test 2 inactive lever presses0.30.42.1-0.4-0.90.2-0.00.1-0.1-0.0-0.40.81.5-0.41.00.1-0.80.4
Total sessions with >9 infusions1.31.43.3-1.8-1.61.2-1.10.91.0-0.9-1.4-0.00.5-1.21.5-0.9-1.31.2
Short access day 1 total inactive lever presses0.00.00.1-0.1-0.20.1-0.20.30.0-0.1-0.2-0.2-0.1-0.00.1-0.2-0.20.1
Short access day 10 total inactive lever presses0.10.11.11.1-0.3-0.0-0.10.40.1-0.1-0.2-0.20.1-0.20.30.3-0.30.2
Short access day 1 total infusions0.70.82.7-1.6-1.10.7-0.70.50.9-0.6-1.00.10.3-0.91.0-0.8-0.80.9
Short access day 10 total infusions0.10.10.30.3-0.2-0.20.2-0.10.2-0.2-0.20.30.4-0.30.30.5-0.20.2
Short access total infusions0.70.72.1-1.4-1.10.8-0.70.70.6-0.7-1.0-0.00.4-1.01.1-0.5-1.00.9
Short access day 1 locomotion0.70.74.40.4-0.8-0.50.5-0.4-0.10.5-0.31.62.1-0.21.00.8-0.40.1
Short access day 10 total locomotion0.20.31.4-0.4-0.3-0.20.3-0.5-0.00.6-0.11.11.2-0.00.4-0.10.1-0.1
Short access total locomotion0.40.41.1-1.0-0.90.5-0.50.40.4-0.2-0.70.30.7-0.60.9-0.6-0.70.5
Compulsive drug intake0.70.72.10.70.1-0.70.8-1.0-0.30.80.61.51.40.50.01.30.4-0.5
One hour access (0.3 mA shock)1.11.25.40.4-0.0-1.21.3-1.3-0.40.80.52.32.30.40.41.20.4-0.4
One hour access (shock baseline)0.10.10.70.10.1-0.60.6-0.4-0.30.10.10.70.8-0.00.10.10.1-0.2
Number of responses in last shaping day0.20.21.10.4-0.4-0.10.2-0.40.20.2-0.21.01.10.00.40.40.00.0
Context. condit. distance diff. score0.30.40.6-0.4-0.70.8-0.70.60.8-0.5-0.6-0.3-0.1-0.80.7-0.5-0.60.7
Locomotion velocity, session 11.01.11.6-0.8-1.21.1-1.11.20.7-1.1-1.1-0.8-0.3-1.11.1-1.1-1.31.0
Locomotion distance, session 11.41.82.4-1.1-1.01.5-1.61.41.5-1.4-1.3-1.3-1.3-1.50.9-1.5-1.01.4
Locomotion velocity, session 20.70.81.5-1.0-0.41.0-1.01.10.6-1.0-0.8-1.2-1.0-0.80.5-1.0-0.80.7
Locomotion distance, session 22.33.37.2-2.3-0.91.8-2.02.31.0-1.8-1.4-2.7-2.2-1.50.8-2.2-1.71.4
Locomotion velocity, session 30.80.91.9-1.1-0.51.0-0.91.20.7-1.2-0.9-1.4-1.1-0.90.5-1.1-0.90.9
Locomotion distance, session 30.10.10.40.20.6-0.20.2-0.1-0.40.20.4-0.3-0.40.2-0.50.20.3-0.4
Stereotopy head waving bouts, day 30.40.41.10.3-1.00.4-0.30.30.8-0.5-0.80.50.8-0.81.0-0.2-0.70.8
Stereotopy head waving duration, day 31.72.13.4-0.9-1.61.5-1.51.31.8-1.6-1.7-0.8-0.5-1.61.4-1.4-1.31.7
Locomotion velocity, session 71.21.32.2-0.8-1.21.2-1.01.21.2-1.3-1.4-0.7-0.2-1.51.3-1.0-1.31.3
Locomotion distance, session 70.40.61.1-1.0-0.70.8-0.81.00.2-0.4-0.6-0.9-0.3-0.70.7-0.9-1.00.6
Stereotopy head waving bouts, day 70.80.91.91.11.3-1.00.6-1.0-0.50.51.00.2-0.51.2-1.40.71.4-1.0
Stereotopy head waving duration, day 70.30.31.9-0.30.40.1-0.50.20.5-0.7-0.2-0.9-1.40.2-0.6-0.50.40.1
Locomotion velocity, session 80.30.31.1-0.30.10.6-0.60.60.5-0.8-0.4-0.9-1.0-0.50.0-0.5-0.30.4
Locomotion distance, session 80.40.61.2-0.8-0.40.9-0.91.00.6-0.8-0.6-1.1-0.9-0.90.4-0.9-0.70.7
Degree of sensitization distance0.60.61.0-0.9-1.00.8-0.80.70.7-0.6-0.9-0.3-0.0-0.70.9-0.9-0.80.8
Degree of sensitization stereotypy0.91.02.80.31.7-0.70.2-0.5-0.70.21.0-0.8-1.51.2-1.70.31.2-1.0
Condit. Reinf. active minus inactive responses1.92.25.52.31.1-1.41.6-1.8-0.71.51.21.81.21.1-0.91.81.5-1.2
Condit. Reinf. active-inactive response ratio0.50.51.81.30.5-0.70.8-0.9-0.20.70.51.00.70.5-0.40.90.8-0.5
Condit. Reinf. active responses2.73.36.02.51.7-1.81.9-2.1-1.41.91.91.71.01.7-1.62.12.0-1.8
Condit. Reinf. inactive responses0.60.81.20.90.9-0.81.0-0.8-1.11.01.10.50.40.8-0.81.00.7-1.0
Incentive salience index mean3.54.28.42.91.7-2.02.2-2.5-1.22.11.82.41.51.7-1.52.52.2-1.8
Condit. Reinf. lever presses2.43.25.32.31.6-1.71.9-2.1-1.31.81.72.01.31.6-1.42.31.8-1.7
Time in familiar zone, hab. session 10.40.41.90.10.50.4-0.30.01.1-1.2-0.3-0.6-1.4-0.2-0.5-0.30.50.4
Time in novel zone, hab. session 10.40.41.90.2-0.3-0.60.5-0.2-1.11.10.40.71.40.30.30.4-0.3-0.5
Total zone transitions, hab. session 10.20.20.70.20.7-0.30.1-0.3-0.30.50.6-0.2-0.70.5-0.80.10.7-0.5
Total locomotion distance, hab. session 11.21.72.81.51.2-1.31.3-1.6-0.81.51.31.30.51.3-1.31.31.7-1.2
Locomotion velocity, hab. session 11.11.62.21.41.1-1.31.3-1.5-0.91.51.31.20.61.2-1.21.31.5-1.2
Time in familiar zone, hab. session 20.30.31.20.5-0.6-0.20.4-0.50.60.2-0.41.10.9-0.10.50.20.10.3
Time in novel zone, hab. session 20.60.61.4-1.1-0.30.8-0.91.10.1-0.7-0.4-1.2-0.8-0.70.4-0.8-0.90.5
Total zone transitions, hab. session 21.62.03.6-1.8-1.21.5-1.71.61.2-1.1-1.3-1.6-1.4-1.20.9-1.9-1.21.3
Total locomotion distance, hab. session 21.11.52.5-1.5-0.91.2-1.51.31.1-1.1-1.0-1.5-1.3-1.00.6-1.6-0.91.1
Locomotion velocity, hab. session 20.91.22.1-1.4-0.91.1-1.41.30.9-1.0-1.0-1.3-1.1-0.90.6-1.4-0.91.0
Novel to familiar place preference ratio0.70.71.5-1.2-0.50.9-1.11.00.6-0.6-0.7-1.2-1.0-0.60.4-1.2-0.70.7
Novelty place preference0.60.61.2-1.1-0.50.8-1.00.90.6-0.5-0.7-1.0-0.9-0.60.4-1.1-0.60.6
Time in novel zone, NPP test0.80.91.6-1.3-0.60.9-1.11.00.8-0.7-0.8-1.1-1.1-0.70.4-1.3-0.60.8
Total zone transitions, NPP test0.00.00.1-0.0-0.10.0-0.30.10.20.1-0.1-0.2-0.4-0.1-0.0-0.30.10.1
Total locomotion distance, NPP test0.10.21.0-0.1-0.50.4-0.50.11.0-0.2-0.40.1-0.3-0.50.2-0.40.10.6
Locomotion velocity, NPP test0.20.20.9-0.0-0.70.4-0.40.11.0-0.1-0.50.30.1-0.60.5-0.4-0.10.7
Pavlov. Cond. lever latency1.21.52.7-1.0-1.31.3-1.11.50.8-1.3-1.2-1.0-0.3-1.51.4-1.2-1.61.3
Pavlov. Cond. magazine entry latency1.82.34.01.91.2-1.61.5-2.0-0.71.61.41.81.01.5-1.31.61.9-1.3
Pavlov. Cond. change in total contacts0.91.02.11.31.0-0.90.8-1.4-0.21.00.91.10.30.8-1.01.11.4-0.8
Pavlov. Cond. index score2.22.84.71.81.4-1.81.6-2.2-0.91.81.52.01.11.7-1.41.82.1-1.5
Pavlov. Cond. latency score2.22.84.81.71.5-1.81.6-2.2-0.81.81.61.80.81.8-1.61.72.2-1.5
Pavlov. Cond. lever contacts0.80.91.80.80.8-1.00.9-1.3-0.31.10.81.20.51.0-0.91.01.3-0.8
Pavlov. Cond. magazine entry number1.41.72.8-1.6-1.11.3-1.21.70.7-1.4-1.3-1.4-0.7-1.41.2-1.4-1.71.2
Pavlov. Cond. intertrial magazine entries0.10.20.60.50.8-0.20.3-0.1-0.50.10.4-0.4-0.50.2-0.50.40.3-0.5
Pavlov. Cond. lever-magazine prob. diff.1.92.44.31.81.1-1.61.6-2.1-0.71.71.32.11.21.5-1.21.81.9-1.3
Pavlov. Cond. response bias2.22.74.21.91.3-1.71.6-2.0-1.01.91.52.01.21.6-1.31.81.9-1.5
Bone: apparent density0.71.13.30.31.6-0.70.3-0.9-0.20.41.0-0.3-1.51.3-1.80.31.7-0.9
Bone surface2.74.78.62.02.9-2.21.8-2.1-2.01.72.50.6-0.52.6-2.91.92.7-2.5
Bone volume1.62.75.71.32.3-1.61.2-1.6-1.31.21.80.3-0.82.1-2.41.22.3-1.8
Bone: connectivity density0.40.73.5-0.21.4-0.2-0.1-0.30.2-0.30.4-0.9-1.90.6-1.4-0.11.1-0.4
Bone: cortical apparent density2.43.18.9-1.0-3.01.2-0.91.31.3-0.7-1.90.82.1-2.02.9-1.1-2.31.9
Bone: cortical area2.23.34.92.11.0-1.92.0-1.8-2.12.11.82.12.21.6-0.82.21.1-1.9
Bone: cortical porosity5.05.46.82.62.3-2.42.3-2.5-2.32.32.51.81.12.6-2.22.52.4-2.6
Bone: cortical porosity5.76.27.92.72.6-2.52.4-2.7-2.32.52.81.80.92.8-2.52.62.7-2.8
Bone: cortical thickness0.50.85.20.7-0.9-0.40.6-0.3-0.60.80.01.52.3-0.11.00.7-0.6-0.1
Bone: cortical thickness0.40.51.3-0.2-1.20.4-0.30.10.90.2-0.70.91.0-0.71.1-0.2-0.50.8
Bone: cortical tissue density2.63.49.2-1.2-3.01.4-1.01.51.4-0.9-2.10.51.8-2.13.0-1.3-2.42.0
Bone: elastic displacement0.50.51.9-0.8-0.60.8-0.70.31.4-0.7-0.9-0.2-0.6-0.80.5-0.7-0.21.0
Bone: elastic work0.10.10.2-0.00.3-0.30.2-0.40.00.20.20.30.00.3-0.30.20.5-0.2
Bone: endosteal estimation2.86.17.92.62.7-2.62.4-2.7-2.22.42.71.70.72.8-2.62.52.8-2.7
Bone: endosteal perimeter2.34.87.42.22.7-2.22.0-2.2-2.12.12.61.00.02.4-2.62.12.5-2.5
Bone: final force1.82.93.61.81.4-1.81.8-1.8-1.91.91.81.61.41.8-1.31.91.4-1.9
Bone: final moment1.01.62.21.30.8-1.41.3-1.4-1.21.51.31.41.21.3-0.81.41.1-1.3
Bone: marrow area2.96.38.02.72.6-2.72.5-2.7-2.22.52.71.80.82.8-2.62.62.8-2.7
Bone: maximum diameter3.86.98.92.82.1-2.82.8-2.7-2.92.82.82.42.12.7-2.03.02.2-2.8
Bone: maximum force1.01.82.31.51.4-1.41.3-1.4-1.31.31.51.00.51.5-1.41.41.5-1.5
Bone: maximum moment0.40.61.00.90.7-0.80.7-1.0-0.50.80.80.70.30.9-0.80.81.0-0.8
Bone: minimum diameter2.24.15.82.41.5-2.22.2-2.1-2.12.22.12.11.91.9-1.32.41.7-2.1
Bone: periosteal estimation3.77.69.73.12.4-3.02.9-2.9-2.82.92.92.51.92.9-2.33.02.6-2.9
Bone: periosteal perimeter2.33.84.92.21.9-2.02.0-2.1-1.92.12.11.61.12.0-1.82.22.0-2.1
Bone: post-yield work0.20.30.8-0.4-0.50.5-0.50.40.9-0.6-0.6-0.3-0.5-0.60.4-0.6-0.20.7
Bone: stiffness2.74.36.12.22.3-2.11.9-2.0-2.32.02.51.00.42.4-2.32.02.1-2.4
Bone: tissue strength0.20.20.7-0.40.10.2-0.40.40.1-0.4-0.1-0.8-0.8-0.0-0.2-0.5-0.10.1
Bone: trabecular number0.81.24.10.01.9-0.60.2-0.6-0.20.10.9-0.9-2.01.2-1.90.11.6-0.9
Bone: trabecular spacing0.20.31.40.0-0.80.10.00.3-0.40.1-0.20.41.2-0.40.90.1-0.90.1
Bone: trabecular thickness0.20.21.3-0.50.40.2-0.4-0.10.6-0.10.0-0.4-1.10.2-0.6-0.40.70.1
Bone: trabecular tissue density1.41.97.51.6-0.3-1.31.5-1.3-1.11.40.72.32.70.90.31.50.4-0.9
Breakpoint value in progressive ratio session0.50.61.20.70.6-0.90.8-1.1-0.20.80.61.10.50.8-0.60.91.0-0.6
Distance traveled before self-admin2.32.53.91.81.8-1.61.4-1.5-1.41.61.80.7-0.12.0-1.91.21.9-1.7
Distance traveled after self-admin0.30.31.00.30.8-0.50.5-0.3-1.00.40.7-0.1-0.10.6-0.70.50.4-0.7
Delta time in closed arm before/after self-admin0.30.30.6-0.50.2-0.50.4-0.7-0.50.80.50.70.50.7-0.40.50.5-0.5
Delta time in open arm before/after self-admin5.35.19.43.12.1-2.22.1-2.3-2.02.42.41.71.02.6-2.12.22.3-2.4
Diff in mean of infusions in LGA sessions0.40.51.50.70.9-0.50.3-0.80.30.40.50.1-0.80.8-1.10.21.2-0.4
Extinction: sum of active levers before priming0.10.10.4-0.10.4-0.20.1-0.40.20.20.2-0.0-0.60.4-0.60.00.6-0.2
Active lever presses in extinction session 60.30.30.8-0.10.4-0.60.6-0.4-0.90.50.60.30.40.5-0.40.50.3-0.6
Delta distance traveled before/after self-admin1.11.21.9-1.4-1.11.2-1.11.20.7-1.2-1.1-0.9-0.3-1.31.1-1.0-1.31.1
Delta ambulatory time before/after self-admin0.91.03.2-1.8-1.10.9-0.71.00.2-0.8-0.9-0.40.4-1.21.2-0.6-1.40.8
Time in closed arm before self-admin2.22.57.02.71.9-1.81.7-1.5-1.21.21.70.80.21.4-1.61.71.7-1.5
Time in closed arm after self-admin1.21.22.01.11.4-1.21.0-1.1-0.81.01.20.4-0.21.4-1.40.91.4-1.2
Time in open arm before self-admin4.75.17.6-2.8-2.72.4-2.22.41.5-2.0-2.4-1.4-0.2-2.52.5-2.3-2.72.3
Time in open arm after self-admin1.21.31.91.30.6-1.11.1-1.1-1.31.41.21.31.41.1-0.61.30.8-1.2
Sum of active levers in priming session hrs 5-61.01.01.9-1.21.1-0.90.8-0.8-1.41.01.20.30.11.2-1.10.80.8-1.2
Time to tail flick, vehicle, before self-admin0.10.10.3-0.5-0.1-0.10.20.1-0.3-0.1-0.00.20.5-0.30.30.2-0.30.1
Time to tail flick, vehicle, after self-admin0.10.10.80.9-0.10.1-0.00.30.0-0.3-0.2-0.2-0.0-0.30.2-0.1-0.30.2
Time to tail flick, test, before self-admin0.10.10.40.10.1-0.10.10.3-0.6-0.00.2-0.30.10.00.00.1-0.3-0.2
Time to tail flick, test, after self-admin2.12.13.1-1.3-1.31.5-1.51.31.8-1.7-1.7-1.1-1.0-1.81.2-1.5-1.21.7
Delta time to tail flick, vehicle, before/after SA0.80.81.10.4-0.61.0-1.00.91.1-0.9-0.9-1.0-1.0-0.80.4-1.1-0.60.9
Delta time to tail flick, test, before/after SA1.61.43.5-1.1-1.21.2-1.10.71.9-1.3-1.5-0.3-0.5-1.41.1-1.1-0.71.6
Ambulatory time before self-admin0.91.02.21.11.3-0.70.4-0.5-0.70.61.0-0.6-1.21.2-1.50.81.1-1.0
Ambulatory time after self-admin0.10.10.3-0.60.10.1-0.20.3-0.4-0.10.1-0.5-0.30.0-0.1-0.2-0.2-0.1
Total heroin consumption0.20.21.0-0.00.2-0.50.5-0.5-0.10.30.20.60.50.2-0.11.00.3-0.2
Area under the delay curve0.10.10.7-0.80.10.2-0.10.1-0.4-0.00.1-0.3-0.30.2-0.20.2-0.0-0.2
Delay disc. indifference point, 0s delay3.74.110.9-3.3-1.82.4-2.22.01.9-2.0-2.1-1.7-1.3-2.01.6-1.4-1.82.1
Delay disc. indifference point, 16s delay0.50.51.1-0.41.0-0.60.9-0.9-0.60.40.90.3-0.10.7-1.00.60.9-0.7
Delay disc. indifference point, 2s delay2.22.43.7-1.7-1.51.9-1.91.71.6-1.6-1.7-1.6-1.4-1.41.1-1.1-1.31.6
Delay disc. indifference point, 24s delay0.20.21.1-1.10.2-0.10.3-0.4-0.40.30.40.30.20.4-0.3-0.50.3-0.3
Delay disc. indifference point, 4s delay1.21.22.6-1.6-1.21.4-1.41.20.9-1.0-1.2-1.0-0.7-1.00.9-0.4-1.11.1
Delay disc. indifference point, 8s delay1.01.12.60.21.4-1.01.0-0.8-1.60.81.30.10.01.3-1.31.00.9-1.3
Delay discount exponential model param0.10.10.50.7-0.2-0.1-0.00.10.4-0.1-0.20.20.3-0.30.3-0.1-0.10.3
Delay discount hyperbolic model param0.10.10.80.90.1-0.40.3-0.20.10.20.10.40.4-0.00.0-0.00.2-0.0
Fecal boli incidents, locomotor time 10.80.91.61.30.6-1.00.9-1.1-0.61.20.80.90.51.1-0.70.91.0-0.9
Change in fecal boli incidents, locomotor task0.20.21.7-1.3-0.30.3-0.30.30.1-0.6-0.3-0.20.0-0.40.40.5-0.50.4
Time >=10cm from walls, locomotor time 10.50.51.00.60.3-0.70.9-0.6-1.00.80.70.70.90.6-0.30.80.3-0.8
Bouts of movement, locomotor time 12.22.56.72.40.6-1.51.8-1.8-0.71.51.02.62.40.7-0.21.81.0-0.9
Total resting periods, locomotor time 11.92.27.82.40.1-1.31.6-1.5-0.41.10.62.62.80.20.51.70.5-0.5
Rest time, locomotor task time 11.11.26.61.6-0.5-0.71.1-0.2-0.2-0.1-0.21.62.6-1.01.40.6-1.00.3
Distance moved, locomotor task time 11.11.23.3-0.61.1-0.30.1-0.3-1.20.91.2-1.0-1.61.6-1.8-0.31.2-1.2
Vertical activity count, locomotor time 10.40.41.7-0.70.30.4-0.50.3-0.50.20.3-1.1-1.30.7-0.90.20.4-0.4
Time >=10cm from walls, locomotor time 21.51.64.9-2.2-0.81.3-1.41.60.4-1.2-1.0-1.9-1.5-0.80.5-1.2-1.20.9
Bouts of movement, locomotor time 20.10.10.5-0.60.10.2-0.10.10.5-0.7-0.1-0.3-0.5-0.5-0.10.1-0.00.4
Total resting periods, locomotor time 20.10.10.3-0.10.1-0.00.2-0.20.3-0.40.00.30.2-0.40.00.60.10.2
Rest time, locomotor task time 21.41.67.82.4-0.3-0.81.3-0.8-0.60.70.32.02.8-0.20.91.3-0.4-0.3
Distance moved, locomotor task time 20.40.52.0-1.10.30.2-0.40.4-0.1-0.10.2-1.1-1.40.4-0.7-1.10.3-0.1
Vertical activity count, locomotor time 23.53.85.9-2.0-1.32.2-2.22.21.8-2.3-1.9-2.4-2.1-1.91.2-1.6-1.72.0
Weight adjusted by age0.30.31.01.00.8-0.20.1-0.40.30.10.3-0.3-1.00.4-0.8-0.20.9-0.2
Seeking ratio, delayed vs. immediate footshock0.50.62.1-0.11.3-0.50.3-0.2-0.5-0.30.8-0.9-1.50.5-1.20.50.8-0.5
Locomotion in novel chamber2.43.09.1-1.0-1.71.6-1.51.13.0-2.1-2.2-0.4-0.8-2.31.6-1.2-1.02.4
Locomotion in novel chamber post-restriction0.50.62.61.6-0.1-0.60.7-0.8-0.10.60.51.21.00.5-0.11.10.6-0.1
Progressive ratio0.70.83.5-1.9-0.70.4-0.30.80.0-1.1-0.6-0.50.1-1.10.8-0.9-1.10.8
Food seeking constrained by brief footshock0.30.41.10.21.0-0.30.2-0.4-0.10.10.6-0.4-1.10.7-1.10.10.9-0.3
Seeking ratio, punishment vs. effort1.01.32.91.21.5-0.60.3-0.9-0.31.11.1-0.1-1.21.6-1.70.71.7-1.1
Run reversals in cocaine runway, females0.10.10.30.4-0.40.5-0.60.40.3-0.1-0.4-0.10.1-0.20.5-0.1-0.40.3
Run reversals in cocaine runway, males1.11.16.62.60.1-0.81.0-1.0-0.20.90.51.51.40.4-0.01.00.6-0.5
Latency to leave start box in cocaine runway4.44.86.6-2.6-2.52.5-2.32.22.1-2.2-2.5-1.3-0.5-2.62.4-1.5-2.42.5
Latency to leave start box in cocaine runway, F2.12.35.3-2.3-2.01.8-1.61.51.2-1.1-1.7-0.60.0-1.41.7-1.3-1.71.5
Latency to leave start box in cocaine runway, M1.41.33.6-0.3-0.81.1-1.00.91.9-1.6-1.4-0.6-0.8-1.71.0-0.1-0.81.6
Cd content in liver0.10.10.5-0.10.4-0.10.1-0.1-0.20.30.3-0.2-0.40.3-0.5-0.70.4-0.3
Co content in liver0.10.10.40.4-0.1-0.00.1-0.40.60.2-0.20.60.2-0.10.10.60.30.2
Cu content in liver0.81.03.01.30.6-0.91.0-0.9-1.11.00.90.91.00.9-0.51.70.6-1.0
Fe content in liver0.20.20.80.10.4-0.30.2-0.70.30.40.30.4-0.40.4-0.60.20.9-0.2
K content in liver1.31.33.01.20.6-1.21.2-1.0-1.31.51.11.11.21.1-0.61.70.8-1.2
Mg content in liver0.00.10.30.20.1-0.20.1-0.2-0.10.30.20.1-0.00.2-0.20.60.2-0.2
Mn content in liver1.01.12.70.5-1.60.7-0.40.41.2-0.5-1.20.81.2-1.31.60.9-1.01.2
Na content in liver2.12.23.01.41.1-1.71.7-1.7-1.41.61.51.61.31.5-1.11.51.4-1.5
Rb content in liver0.50.71.80.21.4-0.50.3-0.2-0.90.20.9-0.8-1.10.8-1.30.60.7-0.9
Se content in liver0.00.00.2-0.3-0.30.3-0.20.10.4-0.0-0.20.1-0.0-0.30.20.0-0.10.3
Sr content in liver0.30.31.7-0.1-0.70.10.10.3-0.50.1-0.20.51.3-0.40.9-0.1-0.90.1
Zn content in liver0.30.30.7-0.5-0.60.7-0.60.70.0-0.3-0.3-0.40.1-0.60.6-0.6-0.80.4