Best TWAS P = 2.68e-08 · Best GWAS P= 1.46e-05 conditioned to 4.59e-40
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain | Map2k6 | isoform ratio | NM_053703.3 | 0.06 | 2887 | 0.03 | 1.0e-03 | 5.55 | 2.89e-08 | 0.37 | FALSE |
| Brain | Map2k6 | isoform ratio | XM_039085033.2 | 0.06 | 2887 | 0.03 | 6.9e-04 | -5.56 | 2.68e-08 | 0.38 | TRUE |
| Liver | Abca6 | intron excision ratio | chr10_95709256_95710607 | 0.08 | 3178 | 0.06 | 8.3e-07 | -5.36 | 8.23e-08 | 0.27 | FALSE |