Hub : Genes

Il18bp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000020150 0.12 0.08 4.7e-10 0.08 0.07 0.07 0.07 4.5e-09 2.0e-08 2.0e-08 1.3e-08
2 BLA gene expression ENSRNOG00000020150 0.13 0.09 3.9e-04 0.01 0.04 0.03 0.03 5.5e-02 3.6e-03 7.8e-03 1.5e-02
3 Brain gene expression ENSRNOG00000020150 0.17 0.1 1.1e-11 0.13 0.13 0.13 0.13 9.2e-12 8.5e-12 9.3e-12 1.0e-11
4 Brain mRNA stability ENSRNOG00000020150 0.03 0.02 4.8e-03 0.01 0.02 0.02 0.01 1.9e-02 1.0e-02 5.2e-03 2.5e-02
5 Liver gene expression ENSRNOG00000020150 0.26 0.13 0.0e+00 0.14 0.14 0.14 0.14 1.6e-15 3.6e-15 1.6e-15 1.8e-15
6 Liver intron excision ratio chr1:156373709:156374048 0.04 0.03 1.7e-03 0.02 0.01 0.01 0.02 2.0e-03 1.7e-02 1.1e-02 5.2e-03
7 NAcc gene expression ENSRNOG00000020150 0.05 0.04 4.3e-03 0.03 0.03 0.03 0.03 2.1e-03 2.5e-03 2.5e-03 3.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail1.65.36.62.52.01.72.12.6-2.52.5
BMI without tail0.10.30.8-0.3-0.8-0.90.5-0.20.2-0.3
Body weight0.31.31.7-1.3-1.2-1.2-0.6-1.21.2-1.3
Epididymis fat weight0.00.10.3-0.00.40.5-0.40.2-0.1-0.0
Glucose0.60.91.41.10.60.41.00.9-1.21.2
Heart weight0.50.61.4-0.4-1.1-1.20.4-0.80.9-0.4
Left kidney weight0.41.22.5-0.8-1.5-1.60.4-1.01.0-0.8
Right kidney weight0.41.11.6-0.9-1.2-1.2-0.1-1.01.3-0.9
Tail length7.823.728.0-5.2-5.3-5.1-2.6-5.34.9-5.2
Length with tail4.315.919.2-4.3-4.1-3.8-2.6-4.44.3-4.2
Length without tail0.00.10.20.10.30.4-0.4-0.10.10.1
Liver weight, left1.11.86.4-1.2-0.10.2-2.5-1.31.3-1.2
Liver weight, right2.54.19.5-2.2-0.8-0.3-3.1-2.12.2-2.2
Parametrial fat weight1.22.43.11.81.61.50.81.6-1.71.7
Retroperitoneal fat weight0.20.62.1-0.30.91.2-1.40.10.2-0.3
Intraocular pressure0.30.50.90.70.50.40.90.8-0.60.7
Extensor digitorum longus weight0.10.20.40.40.60.6-0.00.4-0.40.5
Soleus weight0.20.71.4-1.0-0.2-0.0-1.2-0.71.0-1.0
Tibialis anterior weight0.20.71.0-0.9-0.8-0.7-0.8-1.00.9-0.9
Tibia length0.30.81.6-0.8-1.2-1.30.1-1.00.8-0.7
Number of licking bursts1.51.84.50.81.92.1-0.71.2-0.90.8
Food consumed during 24 hour testing period0.70.82.2-0.3-1.3-1.51.2-0.50.2-0.3
Times rat made contact with spout0.10.10.2-0.40.10.2-0.5-0.20.3-0.4
Mean time between licks in bursts8.111.214.0-3.4-3.7-3.6-1.3-3.63.5-3.4
Mean num. licks in bursts1.51.84.1-1.0-1.9-2.00.6-1.21.0-1.0
Std. dev. time between licks in bursts3.03.64.5-2.0-1.9-1.7-1.3-2.12.1-2.0
Water consumed over 24 hours0.30.30.80.30.80.90.00.6-0.40.3
Indifference point 0 sec0.81.33.0-0.8-1.6-1.70.8-0.90.8-0.9
Indifference point AUC0.50.60.8-0.9-0.9-0.8-0.3-0.90.9-0.9
Indifference point function ln k0.10.10.40.40.0-0.10.60.3-0.40.4
Indifference point function log k0.10.10.40.40.0-0.10.60.3-0.40.4
Delay discounting total patch changes 0 sec0.50.92.2-0.6-1.3-1.50.9-0.60.6-0.6
Delay discounting total patch changes 12 sec1.21.62.1-1.3-1.4-1.4-0.4-1.31.3-1.3
Delay discounting total patch changes 18 sec0.60.71.4-0.8-1.1-1.20.2-0.90.7-0.8
Delay discounting total patch changes 24 sec1.31.62.1-1.2-1.5-1.4-0.1-1.41.4-1.3
Delay discounting total patch changes 6 sec0.30.40.8-0.5-0.8-0.90.3-0.30.8-0.6
Delay discounting time to switch 0 sec1.32.04.90.92.02.2-1.01.2-0.90.9
Delay discounting water rate 0 sec0.91.53.7-0.8-1.8-1.90.7-1.00.7-0.8
Delay discounting water rate 12 sec1.11.75.91.3-0.3-0.62.40.8-1.21.2
Delay discounting water rate 18 sec0.70.92.60.0-1.3-1.61.4-0.5-0.1-0.0
Delay discounting water rate 24 sec0.60.92.01.00.30.11.40.9-1.11.0
Delay discounting water rate 6 sec0.60.82.90.9-0.1-0.31.70.6-0.90.9
Locomotor activity0.10.20.60.2-0.4-0.60.8-0.0-0.20.2
Locomotor testing distance0.50.82.2-0.2-1.3-1.51.1-0.70.1-0.2
Locomotor testing rearing0.71.11.9-1.0-1.3-1.4-0.2-1.20.7-1.0
Light reinforcement 12.54.66.52.12.62.50.82.4-2.12.0
Light reinforcement 24.45.88.02.71.81.52.52.5-2.82.7
Reaction time number correct0.20.30.60.50.40.30.80.6-0.70.5
Reaction time mean minus median0.30.40.6-0.5-0.8-0.8-0.5-0.70.5-0.5
Reaction time mean minus median AUC0.20.20.5-0.4-0.7-0.7-0.3-0.60.2-0.4
Reaction time num false alarms0.50.72.0-0.31.01.3-1.40.20.4-0.4
Reaction time num false alarms AUC0.50.71.9-0.01.11.4-1.20.40.1-0.1
Reaction time trials correct on left0.20.30.60.50.40.30.80.6-0.70.5
Reaction time trials on left0.30.40.70.60.50.40.80.7-0.80.6
Reaction time mean0.50.83.7-0.50.60.8-1.9-0.30.4-0.4
Reaction time mean AUC0.60.83.7-0.40.71.0-1.9-0.20.3-0.3
Median of all reaction times0.70.93.6-0.21.01.3-1.90.10.1-0.1
Reaction time omissions0.50.71.10.71.01.1-0.20.8-1.00.7
Reaction time false alarm rate0.50.71.7-0.01.11.3-1.30.30.1-0.1
Reaction time premature initiation rate1.52.03.3-1.3-1.8-1.8-0.5-1.61.2-1.3
Reaction time premature initiations0.50.71.5-0.6-1.2-1.20.1-0.90.5-0.6
Std. dev. reaction times1.01.43.2-1.2-0.7-0.5-1.8-1.21.1-1.1
Reaction time trials completed0.30.40.70.60.50.40.80.7-0.80.6
Reaction time trials AUC0.10.20.40.40.30.20.70.4-0.60.4
Social response proportion0.10.10.4-0.10.50.6-0.20.50.3-0.1
Social responses0.40.51.3-0.7-0.00.1-1.1-0.40.8-0.8
Social time1.31.63.11.11.71.8-0.11.3-1.21.1
Conditioned locomotion0.30.31.3-0.5-0.00.1-1.1-0.60.5-0.5
Cocaine response after cond. corrected0.50.61.50.51.11.2-0.40.8-0.40.5
Cocaine response after cond. not corrected0.91.01.31.01.21.10.51.2-0.91.0
Cocaine response before conditioning0.70.92.90.9-0.2-0.51.70.6-0.90.9
Saline control response3.54.76.1-2.2-2.5-2.4-1.0-2.42.2-2.2
Condit. Reinf. active minus inactive responses5.46.712.7-2.2-3.4-3.60.1-2.82.2-2.2
Condit. Reinf. active-inactive response ratio0.60.71.7-0.5-1.2-1.30.6-0.80.5-0.5
Condit. Reinf. active responses7.410.318.1-2.9-4.1-4.3-0.2-3.52.9-2.9
Condit. Reinf. inactive responses4.96.19.1-2.4-3.0-3.0-0.7-2.72.4-2.4
Condit. Reinf. lever presses6.89.422.1-2.2-4.3-4.71.1-3.02.2-2.2
Condit. Reinf. lever reinforcers received7.410.419.0-2.8-4.2-4.4-0.1-3.52.9-2.8
Pavlov. Cond. lever latency6.08.322.11.64.24.7-1.82.6-1.61.6
Pavlov. Cond. magazine entry latency1.51.76.51.0-0.8-1.22.50.5-1.11.0
Pavlov. Cond. change in total contacts4.96.818.7-1.3-3.8-4.32.1-2.21.3-1.3
Pavlov. Cond. index score3.74.814.0-0.8-3.3-3.72.1-1.70.8-0.8
Pavlov. Cond. latency score3.03.811.2-0.4-2.8-3.32.3-1.30.4-0.4
Pavlov. Cond. lever contacts6.69.123.4-1.9-4.4-4.81.7-2.81.9-1.9
Pavlov. Cond. magazine entry number1.72.16.1-0.31.82.3-2.50.30.3-0.3
Pavlov. Cond. intertrial magazine entries1.92.43.3-1.8-1.2-1.0-1.5-1.61.8-1.8
Pavlov. Cond. lever-magazine prob. diff.3.74.813.7-0.9-3.2-3.72.0-1.70.9-0.9
Pavlov. Cond. response bias5.88.122.1-1.4-4.2-4.72.2-2.41.5-1.4
Conditioned reinforcement - actives0.10.10.30.3-0.2-0.30.40.1-0.50.4
Conditioned reinforcement - inactives0.30.31.2-0.40.10.3-1.1-0.50.7-0.4
Conditioned locomotion0.50.51.90.6-0.3-0.61.40.4-0.70.7
Intermittent access intake day 1-15 change1.31.33.01.30.40.11.71.1-1.11.3
Intermittent access intake escalation1.61.53.01.50.50.31.71.2-1.21.5
Intermittent access intake escalation 20.70.71.11.00.70.60.80.9-0.81.0
Intermitt. access day 1 inactive lever presses0.50.61.9-0.50.60.9-1.4-0.20.6-0.6
Intermitt. access day 15 inactive lever presses0.10.10.3-0.1-0.4-0.40.2-0.20.5-0.2
Intermitt. access escalation Index0.30.30.6-0.6-0.3-0.3-0.4-0.40.6-0.8
Intermittent access day 1 total infusions1.01.21.9-1.0-1.4-1.4-0.6-1.30.7-0.9
Intermittent access day 15 total infusions0.20.20.60.1-0.6-0.80.3-0.3-0.10.1
Intermittent access terminal intake (last 3 days)0.20.20.8-0.2-0.8-0.9-0.0-0.5-0.1-0.1
Intermittent access total infusions0.30.30.7-0.5-0.8-0.9-0.2-0.70.1-0.4
Intermittent access day 1 locomotion0.20.20.4-0.5-0.3-0.2-0.7-0.50.4-0.5
Intermittent access day 15 total locomotion0.20.30.90.5-0.0-0.21.00.4-0.50.5
Intermittent access total locomotion0.10.10.4-0.2-0.5-0.60.3-0.30.0-0.1
Intermittent access standard deviation0.70.81.11.00.80.70.81.0-0.81.0
Cocaine induced anxiety0.80.92.5-0.31.31.6-1.40.30.3-0.2
Post-drug Anxiety1.61.83.2-1.6-0.5-0.2-1.8-1.21.5-1.6
Baseline Anxiety2.22.43.9-1.4-2.0-2.0-0.4-1.71.3-1.5
Lifetime Intake0.30.41.1-0.3-1.0-1.10.1-0.7-0.0-0.2
Incentive Sensitization - Responses0.90.91.3-1.0-1.1-1.1-0.6-1.10.7-0.9
Incentive Sensitization - Breakpoint0.50.50.8-0.7-0.9-0.9-0.3-0.80.4-0.6
Progressive ratio test 1 active lever presses0.00.00.0-0.0-0.2-0.2-0.1-0.2-0.20.1
Progressive ratio test 1 breakpoint0.00.10.1-0.2-0.3-0.3-0.3-0.3-0.1-0.1
Progressive ratio test 1 inactive lever presses0.00.00.10.0-0.2-0.1-0.2-0.3-0.00.0
Progressive ratio test 2 active lever presses0.40.50.8-0.7-0.8-0.7-0.7-0.90.3-0.5
Progressive ratio test 2 breakpoint0.50.60.9-0.8-0.9-0.8-0.7-1.00.5-0.6
Progressive ratio test 2 inactive lever presses0.00.00.10.1-0.2-0.3-0.1-0.2-0.20.1
Total sessions with >9 infusions0.91.02.30.6-1.0-1.31.5-0.0-1.00.6
Short access day 1 total inactive lever presses0.40.41.6-0.50.10.3-1.3-0.50.7-0.5
Short access day 10 total inactive lever presses0.30.41.10.30.91.1-0.20.6-0.20.2
Short access day 1 total infusions0.91.02.5-0.6-1.5-1.6-0.1-1.10.3-0.6
Short access day 10 total infusions0.60.71.7-0.6-1.2-1.30.0-1.00.2-0.6
Short access total infusions0.50.61.7-0.3-1.2-1.30.1-0.80.1-0.3
Short access day 1 locomotion0.90.91.61.20.2-0.11.20.7-1.21.3
Short access day 10 total locomotion0.20.30.40.40.40.30.60.6-0.70.4
Short access total locomotion0.20.20.50.50.20.10.40.4-0.70.5
Compulsive drug intake0.60.60.90.90.90.90.40.8-0.50.8
One hour access (0.3 mA shock)0.20.30.60.4-0.4-0.60.80.0-0.60.5
One hour access (shock baseline)0.40.51.3-0.4-1.0-1.10.1-0.70.2-0.3
Number of responses in last shaping day0.70.71.3-0.8-0.7-0.6-1.1-1.10.7-0.8
Context. condit. distance diff. score0.91.13.2-0.1-1.5-1.81.1-0.70.1-0.1
Locomotion velocity, session 12.22.33.01.71.41.21.21.7-1.71.7
Locomotion distance, session 10.60.81.71.00.2-0.11.30.8-1.21.0
Locomotion velocity, session 20.91.11.81.10.60.41.31.0-1.31.1
Locomotion distance, session 20.81.12.31.20.50.21.51.0-1.31.2
Locomotion velocity, session 30.20.20.7-0.2-0.8-0.90.2-0.50.1-0.2
Locomotion distance, session 30.20.20.60.1-0.6-0.80.6-0.2-0.30.1
Stereotopy head waving bouts, day 30.50.61.0-0.9-0.4-0.3-1.0-0.71.0-0.9
Stereotopy head waving duration, day 30.00.00.2-0.0-0.1-0.20.50.20.0-0.0
Locomotion velocity, session 70.91.01.61.10.80.70.91.0-1.31.1
Locomotion distance, session 70.00.10.10.10.30.4-0.40.0-0.20.1
Stereotopy head waving bouts, day 71.11.23.2-0.7-1.6-1.80.7-0.90.5-0.7
Stereotopy head waving duration, day 70.91.13.2-0.5-1.6-1.81.0-0.80.4-0.5
Locomotion velocity, session 80.50.61.8-0.3-1.2-1.30.5-0.90.4-0.3
Locomotion distance, session 80.60.92.20.3-1.2-1.51.5-0.2-0.40.3
Degree of sensitization distance0.60.61.2-0.8-0.2-0.1-1.1-0.70.9-0.8
Degree of sensitization stereotypy2.02.26.2-0.8-2.2-2.51.0-1.30.6-0.8
Condit. Reinf. active minus inactive responses2.12.42.9-1.7-1.5-1.3-1.2-1.61.7-1.7
Condit. Reinf. active-inactive response ratio4.04.35.4-2.3-2.0-1.8-1.6-2.22.3-2.3
Condit. Reinf. active responses1.11.31.8-1.3-0.8-0.6-1.3-1.11.4-1.3
Condit. Reinf. inactive responses0.30.30.60.50.80.8-0.10.6-0.40.5
Incentive salience index mean1.31.52.1-1.4-1.0-0.9-1.1-1.21.4-1.4
Condit. Reinf. lever presses0.00.00.1-0.20.10.1-0.30.00.2-0.2
Time in familiar zone, hab. session 10.10.10.2-0.1-0.4-0.50.2-0.30.1-0.1
Time in novel zone, hab. session 10.20.20.5-0.50.10.2-0.7-0.20.4-0.5
Total zone transitions, hab. session 10.20.30.70.60.1-0.10.80.5-0.60.6
Total locomotion distance, hab. session 10.71.01.5-1.2-0.5-0.4-1.1-0.91.2-1.2
Locomotion velocity, hab. session 10.40.50.8-0.9-0.3-0.2-0.8-0.60.9-0.9
Time in familiar zone, hab. session 23.13.34.5-1.8-2.1-2.1-0.5-2.01.8-1.8
Time in novel zone, hab. session 23.73.74.62.11.91.81.22.1-2.12.1
Total zone transitions, hab. session 20.60.72.00.1-1.2-1.41.2-0.30.20.1
Total locomotion distance, hab. session 21.11.52.2-1.3-1.3-1.2-0.6-1.31.5-1.3
Locomotion velocity, hab. session 21.11.52.3-1.3-1.2-1.2-0.7-1.31.5-1.3
Novel to familiar place preference ratio2.52.63.7-1.9-1.2-0.9-1.5-1.61.9-1.9
Novelty place preference2.32.43.3-1.8-1.2-1.0-1.4-1.61.8-1.8
Time in novel zone, NPP test2.72.83.8-1.9-1.4-1.2-1.5-1.82.0-1.9
Total zone transitions, NPP test1.21.72.31.50.80.61.51.4-1.51.5
Total locomotion distance, NPP test0.20.30.50.50.60.60.30.7-0.50.5
Locomotion velocity, NPP test0.50.71.00.81.00.90.41.0-0.80.8
Pavlov. Cond. lever latency0.81.01.31.01.11.10.41.1-1.01.0
Pavlov. Cond. magazine entry latency1.41.84.3-0.9-1.9-2.10.3-1.40.9-0.9
Pavlov. Cond. change in total contacts2.22.42.9-1.6-1.6-1.6-0.9-1.71.6-1.6
Pavlov. Cond. index score1.31.73.3-1.1-1.7-1.8-0.0-1.41.0-1.1
Pavlov. Cond. latency score1.41.73.1-1.2-1.7-1.8-0.2-1.41.1-1.2
Pavlov. Cond. lever contacts0.60.71.0-0.8-1.0-1.0-0.3-0.90.8-0.8
Pavlov. Cond. magazine entry number1.21.53.60.81.71.9-0.31.2-0.90.8
Pavlov. Cond. intertrial magazine entries0.20.30.80.10.80.9-0.60.3-0.10.1
Pavlov. Cond. lever-magazine prob. diff.1.01.32.6-1.0-1.5-1.6-0.0-1.20.9-1.0
Pavlov. Cond. response bias0.60.71.4-0.6-1.1-1.2-0.1-0.90.7-0.6
Bone: apparent density0.10.10.30.30.50.5-0.00.4-0.30.3
Bone surface0.71.21.5-1.1-1.2-1.2-0.5-1.21.1-1.1
Bone volume0.50.81.1-1.0-1.0-0.9-0.5-1.01.0-1.0
Bone: connectivity density1.11.72.21.51.10.91.21.3-1.51.5
Bone: cortical apparent density0.30.41.0-0.40.60.8-1.00.00.3-0.4
Bone: cortical area0.40.71.0-0.8-0.9-0.9-0.5-1.00.8-0.8
Bone: cortical porosity0.20.20.4-0.5-0.6-0.5-0.3-0.60.4-0.5
Bone: cortical porosity0.30.30.4-0.5-0.6-0.5-0.3-0.60.6-0.5
Bone: cortical thickness0.50.81.00.90.90.80.60.9-1.00.9
Bone: cortical thickness0.00.00.0-0.0-0.1-0.1-0.1-0.10.0-0.0
Bone: cortical tissue density0.30.40.9-0.40.70.9-0.90.10.3-0.4
Bone: elastic displacement2.63.03.81.71.91.90.91.9-1.71.7
Bone: elastic work5.16.68.02.72.72.61.52.8-2.72.7
Bone: endosteal estimation1.94.05.5-1.9-2.2-2.1-1.4-2.42.0-1.9
Bone: endosteal perimeter1.93.85.2-1.8-2.3-2.3-1.0-2.21.9-1.8
Bone: final force1.01.72.9-1.5-0.6-0.3-1.7-1.31.5-1.5
Bone: final moment1.01.62.2-1.5-0.7-0.5-1.5-1.31.5-1.5
Bone: marrow area1.73.75.0-1.9-2.0-1.9-1.4-2.22.0-1.9
Bone: maximum diameter1.93.55.2-1.7-2.3-2.3-0.7-2.11.8-1.7
Bone: maximum force0.61.11.7-1.2-0.6-0.5-1.3-1.21.1-1.2
Bone: maximum moment0.50.81.1-1.0-0.7-0.6-1.0-1.01.0-1.0
Bone: minimum diameter1.73.24.2-1.9-1.7-1.6-1.5-2.11.8-1.9
Bone: periosteal estimation1.22.43.5-1.5-1.7-1.7-1.0-1.91.5-1.5
Bone: periosteal perimeter1.01.72.7-1.1-1.6-1.7-0.4-1.51.1-1.1
Bone: post-yield work0.10.10.3-0.1-0.5-0.50.0-0.50.0-0.1
Bone: stiffness2.43.76.5-2.2-0.9-0.5-2.6-1.82.3-2.2
Bone: tissue strength3.13.03.91.91.51.31.61.9-2.01.9
Bone: trabecular number1.11.72.41.31.51.50.41.4-1.31.3
Bone: trabecular spacing0.50.61.70.80.0-0.21.30.7-0.90.8
Bone: trabecular thickness1.92.33.2-1.7-0.9-0.7-1.8-1.61.7-1.7
Bone: trabecular tissue density3.44.89.3-2.6-0.9-0.4-3.1-2.02.4-2.6
Breakpoint value in progressive ratio session1.01.12.31.10.80.70.91.0-1.51.0
Distance traveled before self-admin1.01.11.51.21.11.10.31.0-0.91.2
Distance traveled after self-admin0.70.81.51.20.20.11.00.6-1.01.2
Delta time in closed arm before/after self-admin0.70.71.8-1.00.10.3-1.4-0.50.8-1.0
Delta time in open arm before/after self-admin2.32.23.4-1.2-1.8-1.8-0.4-1.71.8-1.2
Diff in mean of infusions in LGA sessions0.91.03.1-1.00.20.6-1.8-0.61.0-1.1
Extinction: sum of active levers before priming0.20.20.30.50.40.40.10.4-0.40.5
Active lever presses in extinction session 60.40.41.50.4-0.3-0.51.20.4-0.40.3
Delta distance traveled before/after self-admin2.22.44.2-1.4-2.0-2.0-0.4-1.81.2-1.4
Delta ambulatory time before/after self-admin1.31.42.8-1.0-1.6-1.7-0.0-1.30.8-1.0
Time in closed arm before self-admin0.60.72.30.5-0.8-1.11.50.0-0.50.6
Time in closed arm after self-admin0.10.10.40.00.60.6-0.30.3-0.20.1
Time in open arm before self-admin2.83.07.11.22.52.7-0.41.8-1.21.2
Time in open arm after self-admin0.30.30.7-0.5-0.3-0.2-0.6-0.50.9-0.6
Sum of active levers in priming session hrs 5-60.20.20.50.60.1-0.00.70.3-0.60.5
Time to tail flick, vehicle, before self-admin0.10.10.20.1-0.4-0.40.1-0.3-0.10.1
Time to tail flick, vehicle, after self-admin0.70.71.9-0.5-1.3-1.40.2-0.90.4-0.5
Time to tail flick, test, before self-admin2.12.02.7-1.5-1.6-1.6-0.4-1.51.6-1.4
Time to tail flick, test, after self-admin4.54.66.1-2.4-2.1-2.0-1.2-2.22.5-2.4
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.1-0.3-0.40.4-0.1-0.0-0.1
Delta time to tail flick, test, before/after SA0.10.10.10.20.30.40.00.3-0.10.1
Ambulatory time before self-admin1.01.11.61.21.21.20.11.0-1.01.2
Ambulatory time after self-admin0.20.30.40.7-0.3-0.40.70.0-0.60.6
Total heroin consumption0.20.20.80.2-0.4-0.60.90.0-0.40.2
Area under the delay curve0.20.20.8-0.30.30.5-0.9-0.10.2-0.3
Delay disc. indifference point, 0s delay0.20.20.4-0.3-0.6-0.70.1-0.40.3-0.4
Delay disc. indifference point, 16s delay0.70.71.9-1.0-0.10.1-1.4-0.60.8-1.0
Delay disc. indifference point, 2s delay0.91.01.3-1.1-1.0-1.0-0.7-1.11.0-1.1
Delay disc. indifference point, 24s delay0.40.41.4-0.30.70.9-1.20.10.2-0.3
Delay disc. indifference point, 4s delay1.11.21.4-1.1-1.1-1.1-0.7-1.21.1-1.1
Delay disc. indifference point, 8s delay0.10.10.20.00.40.5-0.40.2-0.40.1
Delay discount exponential model param0.20.20.60.2-0.5-0.60.8-0.10.00.1
Delay discount hyperbolic model param0.10.20.60.3-0.2-0.40.80.1-0.20.3
Fecal boli incidents, locomotor time 10.40.41.20.21.01.1-0.50.5-0.50.1
Change in fecal boli incidents, locomotor task0.10.10.1-0.3-0.3-0.3-0.1-0.20.3-0.3
Time >=10cm from walls, locomotor time 10.70.70.9-0.9-0.9-0.90.1-0.80.8-0.9
Bouts of movement, locomotor time 10.70.81.5-0.9-0.6-0.5-0.8-0.91.2-0.9
Total resting periods, locomotor time 10.10.10.3-0.4-0.00.1-0.5-0.30.5-0.3
Rest time, locomotor task time 10.40.40.6-0.8-0.5-0.5-0.8-0.70.4-0.8
Distance moved, locomotor task time 10.10.10.20.30.20.10.40.2-0.20.2
Vertical activity count, locomotor time 10.00.00.1-0.2-0.00.0-0.3-0.20.2-0.2
Time >=10cm from walls, locomotor time 23.53.75.1-1.9-2.3-2.2-0.7-2.22.0-1.9
Bouts of movement, locomotor time 22.72.94.1-2.0-1.3-1.0-1.7-1.91.8-1.9
Total resting periods, locomotor time 21.71.82.8-1.6-0.8-0.5-1.7-1.51.4-1.6
Rest time, locomotor task time 21.41.73.21.01.71.8-0.31.3-1.41.0
Distance moved, locomotor task time 21.41.63.5-1.0-1.8-1.90.3-1.31.0-1.0
Vertical activity count, locomotor time 21.31.41.7-1.3-1.1-1.0-1.1-1.31.1-1.3
Weight adjusted by age0.70.81.4-0.6-1.2-1.20.1-1.00.9-0.6
Seeking ratio, delayed vs. immediate footshock1.71.93.11.41.71.80.21.4-1.31.3
Locomotion in novel chamber2.12.53.31.81.41.31.41.8-1.51.8
Locomotion in novel chamber post-restriction0.40.51.80.6-0.2-0.41.30.3-0.50.7
Progressive ratio0.50.61.01.00.50.40.80.8-0.51.0
Food seeking constrained by brief footshock1.72.13.0-1.4-1.7-1.7-0.1-1.41.6-1.4
Seeking ratio, punishment vs. effort1.72.13.0-1.7-1.5-1.5-0.7-1.51.2-1.7
Run reversals in cocaine runway, females0.30.30.5-0.6-0.7-0.7-0.2-0.60.3-0.7
Run reversals in cocaine runway, males0.20.20.40.20.60.7-0.20.3-0.10.3
Latency to leave start box in cocaine runway0.30.30.7-0.10.80.9-0.80.3-0.50.1
Latency to leave start box in cocaine runway, F0.40.41.5-0.70.20.4-1.2-0.30.3-0.7
Latency to leave start box in cocaine runway, M0.90.81.40.71.01.00.31.0-1.20.9
Cd content in liver0.20.20.40.30.60.7-0.50.2-0.40.3
Co content in liver4.65.56.5-2.5-2.4-2.3-1.5-2.62.5-2.5
Cu content in liver2.32.83.4-1.8-1.7-1.6-1.1-1.81.8-1.8
Fe content in liver0.70.81.3-1.0-0.5-0.3-1.1-0.91.0-1.0
K content in liver0.20.20.60.10.70.8-0.30.4-0.10.1
Mg content in liver0.00.00.10.20.10.10.30.3-0.10.2
Mn content in liver2.52.93.91.82.02.00.51.8-1.71.7
Na content in liver0.00.00.1-0.0-0.3-0.30.3-0.10.10.1
Rb content in liver0.70.91.1-1.0-1.0-1.0-0.5-1.00.9-1.0
Se content in liver1.82.25.21.12.12.3-0.71.3-1.01.1
Sr content in liver1.81.73.11.40.70.51.81.3-1.41.4
Zn content in liver0.60.72.00.2-1.0-1.31.4-0.1-0.30.1