Prr3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000025806 0.14 0.11 1.9e-04 0.06 0.04 0.04 0.05 4.0e-04 1.9e-03 2.3e-03 1.0e-03
2 Brain gene expression ENSRNOG00000025806 0.16 0.08 1.1e-13 0.13 0.12 0.12 0.13 3.6e-12 2.7e-11 1.8e-11 8.2e-12
3 Brain isoform ratio ENSRNOT00000035838 0.07 0.05 8.3e-06 0.06 0.05 0.05 0.05 1.7e-06 2.1e-05 1.2e-05 1.2e-05
4 Brain isoform ratio ENSRNOT00000089869 0.11 0.06 7.6e-10 0.1 0.09 0.09 0.09 4.1e-09 5.5e-09 8.9e-09 6.2e-09
5 Brain intron excision ratio chr20:2793006:2793683 0.06 0.04 2.2e-04 0.03 0.04 0.02 0.03 7.6e-04 2.7e-04 6.5e-03 2.2e-03
6 Brain intron excision ratio chr20:2793415:2793683 0.04 0.03 6.5e-03 0 0.01 -0 0 2.7e-01 4.6e-02 7.7e-01 3.6e-01
7 Liver isoform ratio ENSRNOT00000035838 0.03 0.02 2.9e-03 0.02 0.02 0.01 0.01 3.6e-03 5.5e-03 1.5e-02 6.9e-03
8 Liver isoform ratio ENSRNOT00000119862 0.02 0.02 7.3e-03 0.02 0.01 0.01 0.01 1.9e-03 2.1e-02 9.2e-03 1.0e-02
9 PL gene expression ENSRNOG00000025806 0.1 0.06 4.6e-06 0.03 0.03 0.01 0.02 1.6e-03 2.3e-03 3.3e-02 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail1.65.17.8-2.4-2.6-2.72.80.4-1.02.0-2.4-2.6
BMI without tail2.75.79.6-1.8-2.4-2.93.11.5-1.91.9-2.9-2.4
Body weight5.523.133.5-4.3-4.5-5.85.83.4-4.34.5-5.6-4.5
Epididymis fat weight4.29.919.0-4.3-4.0-1.61.4-4.43.51.4-1.3-4.0
Glucose2.63.99.32.42.30.5-0.53.1-2.5-0.80.42.6
Heart weight0.20.41.9-0.5-0.3-0.30.50.5-0.51.4-0.3-0.2
Left kidney weight3.610.313.9-3.3-3.2-3.63.71.8-2.43.6-3.7-3.1
Right kidney weight3.08.512.8-2.1-2.5-3.43.62.6-3.02.6-3.6-2.4
Tail length4.413.427.4-1.3-1.9-4.14.25.0-5.23.0-4.1-1.9
Length with tail4.115.123.4-2.6-2.5-4.54.44.4-4.83.8-4.4-2.6
Length without tail3.27.09.5-2.3-2.0-3.12.82.4-2.73.1-2.9-2.2
Liver weight, left0.71.13.7-0.00.0-0.90.91.9-1.90.2-1.1-0.0
Liver weight, right3.76.214.5-1.0-0.8-2.62.53.7-3.82.3-2.6-0.7
Parametrial fat weight1.93.85.5-2.3-2.3-2.12.30.4-0.91.6-2.3-2.3
Retroperitoneal fat weight0.31.12.0-1.4-1.0-1.11.10.2-0.50.8-1.4-1.2
Intraocular pressure1.01.43.00.81.01.2-1.2-0.71.0-1.71.61.1
Extensor digitorum longus weight0.10.61.90.90.3-0.30.51.4-1.30.1-0.50.4
Soleus weight1.44.115.11.80.9-0.91.03.9-3.60.8-1.01.1
Tibialis anterior weight0.20.62.3-0.1-0.80.00.1-1.51.3-0.50.0-0.8
Tibia length2.67.314.7-1.3-1.3-3.12.93.6-3.82.7-2.7-1.2
Number of licking bursts0.50.61.71.31.00.4-0.40.9-0.7-0.10.41.0
Food consumed during 24 hour testing period0.81.02.5-0.1-0.3-1.11.11.6-1.60.5-1.1-0.1
Times rat made contact with spout1.72.04.80.20.31.3-1.4-2.12.2-1.71.30.3
Mean time between licks in bursts1.31.85.61.41.40.0-0.02.4-2.0-0.10.11.5
Mean num. licks in bursts0.91.13.5-1.2-0.70.3-0.3-1.91.7-0.80.3-0.8
Std. dev. time between licks in bursts1.51.75.91.31.0-0.30.32.4-2.20.7-0.41.2
Water consumed over 24 hours0.10.10.20.20.2-0.10.10.5-0.40.3-0.10.3
Indifference point 0 sec0.61.02.0-1.3-1.1-0.40.3-1.41.10.4-0.9-1.2
Indifference point AUC1.92.23.6-0.7-1.6-1.81.91.0-1.31.3-1.7-1.6
Indifference point function ln k0.40.51.30.81.00.7-0.60.4-0.2-0.40.81.1
Indifference point function log k0.40.51.30.81.00.7-0.60.4-0.2-0.40.81.1
Delay discounting total patch changes 0 sec0.81.32.4-1.4-1.4-0.60.5-1.61.20.5-1.0-1.6
Delay discounting total patch changes 12 sec1.11.42.7-1.3-1.5-0.80.8-1.30.91.0-1.1-1.7
Delay discounting total patch changes 18 sec1.31.85.8-1.2-1.4-0.00.0-2.42.1-0.3-0.1-1.4
Delay discounting total patch changes 24 sec1.72.18.1-0.3-0.51.1-1.0-2.82.7-0.50.6-0.8
Delay discounting total patch changes 6 sec1.01.53.7-1.3-1.6-0.50.4-1.91.50.2-0.7-1.6
Delay discounting time to switch 0 sec0.50.82.6-0.8-0.10.8-0.6-1.61.6-0.40.5-0.1
Delay discounting water rate 0 sec0.30.50.8-0.2-0.9-0.90.90.2-0.30.9-0.6-0.9
Delay discounting water rate 12 sec0.30.41.20.0-0.20.4-0.6-1.11.0-0.30.7-0.2
Delay discounting water rate 18 sec0.20.30.50.4-0.3-0.70.70.5-0.5-0.1-0.7-0.5
Delay discounting water rate 24 sec1.31.83.1-1.1-1.6-1.61.80.4-0.71.2-1.3-1.6
Delay discounting water rate 6 sec0.10.20.6-0.2-0.4-0.0-0.0-0.80.70.00.4-0.5
Locomotor activity1.72.88.7-0.1-0.1-1.31.43.0-2.91.1-1.70.3
Locomotor testing distance0.30.51.60.10.0-0.50.41.3-1.20.4-0.80.4
Locomotor testing rearing0.71.12.8-0.2-0.1-0.90.81.7-1.71.0-1.20.1
Light reinforcement 10.30.51.9-1.4-0.5-0.2-0.1-0.90.70.5-0.1-0.8
Light reinforcement 20.60.81.4-0.7-0.4-1.20.81.0-1.10.5-1.0-0.8
Reaction time number correct0.50.72.1-1.2-0.8-0.10.3-1.51.20.2-0.1-0.9
Reaction time mean minus median2.02.68.41.41.9-0.1-0.12.9-2.5-0.7-0.31.5
Reaction time mean minus median AUC1.41.85.01.31.80.2-0.42.2-1.9-0.90.11.4
Reaction time num false alarms0.40.51.0-0.2-0.7-1.00.70.7-0.90.8-0.7-0.4
Reaction time num false alarms AUC0.60.91.5-0.3-0.9-1.20.90.9-1.01.2-1.0-0.7
Reaction time trials correct on left0.50.72.1-1.2-0.8-0.10.3-1.51.20.2-0.1-0.9
Reaction time trials on left0.50.71.8-1.2-0.8-0.10.3-1.31.10.2-0.2-0.8
Reaction time mean2.02.75.92.22.00.4-0.62.4-2.0-1.10.41.9
Reaction time mean AUC2.02.66.12.12.00.4-0.62.5-2.0-1.10.31.9
Median of all reaction times1.41.84.42.11.60.4-0.61.8-1.4-1.00.51.5
Reaction time omissions1.41.84.71.81.60.3-0.32.2-1.8-0.80.21.4
Reaction time false alarm rate0.60.92.60.5-0.3-1.00.61.6-1.61.0-0.80.0
Reaction time premature initiation rate1.11.52.5-1.1-1.5-1.31.30.3-0.61.4-1.2-1.6
Reaction time premature initiations1.62.24.5-1.7-1.9-1.41.5-0.4-0.01.5-1.4-2.1
Std. dev. reaction times2.02.89.41.61.8-0.2-0.03.1-2.7-0.5-0.41.5
Reaction time trials completed0.50.71.8-1.2-0.8-0.10.3-1.31.10.2-0.2-0.8
Reaction time trials AUC0.40.61.9-1.1-0.7-0.10.2-1.41.20.1-0.1-0.8
Social response proportion0.40.41.4-0.20.4-0.10.11.0-0.91.2-0.50.2
Social responses0.30.42.3-0.6-0.2-0.50.30.4-0.51.5-0.5-0.3
Social time1.41.86.80.81.0-0.30.22.6-2.30.9-0.51.0
Conditioned locomotion0.60.71.30.2-0.6-0.91.01.0-1.10.4-1.0-0.5
Cocaine response after cond. corrected0.40.50.80.60.60.9-0.8-0.60.7-0.80.80.5
Cocaine response after cond. not corrected0.30.31.00.00.2-0.40.41.0-1.00.5-0.40.1
Cocaine response before conditioning4.85.98.7-1.8-1.4-2.82.72.7-2.92.9-2.7-1.4
Saline control response1.31.74.2-2.0-1.8-1.11.1-0.90.50.7-1.1-1.7
Condit. Reinf. active minus inactive responses1.11.41.9-0.6-0.9-1.31.41.0-1.21.4-1.4-1.0
Condit. Reinf. active-inactive response ratio2.52.74.0-0.8-1.1-1.91.91.6-1.92.0-1.9-1.2
Condit. Reinf. active responses0.00.00.10.30.10.1-0.00.1-0.1-0.00.00.0
Condit. Reinf. inactive responses1.41.82.70.81.21.6-1.6-1.01.2-1.61.61.2
Condit. Reinf. lever presses0.40.50.90.90.60.8-0.8-0.40.5-0.80.90.6
Condit. Reinf. lever reinforcers received0.10.10.30.50.40.2-0.20.2-0.1-0.10.20.2
Pavlov. Cond. lever latency0.20.30.5-0.3-0.2-0.60.60.6-0.70.7-0.7-0.3
Pavlov. Cond. magazine entry latency0.60.71.0-0.5-0.6-0.91.00.9-1.00.9-1.0-0.5
Pavlov. Cond. change in total contacts0.20.30.8-0.6-0.9-0.50.5-0.40.20.3-0.4-0.7
Pavlov. Cond. index score0.00.00.1-0.1-0.2-0.10.20.0-0.0-0.0-0.1-0.1
Pavlov. Cond. latency score0.10.10.2-0.3-0.5-0.30.40.0-0.10.2-0.3-0.3
Pavlov. Cond. lever contacts0.30.31.1-0.3-0.30.4-0.3-1.11.0-0.50.5-0.2
Pavlov. Cond. magazine entry number0.30.40.60.50.70.7-0.8-0.30.4-0.50.70.6
Pavlov. Cond. intertrial magazine entries1.62.04.31.72.11.2-1.30.9-0.5-1.21.31.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.1-0.3-0.10.20.0-0.0-0.0-0.1-0.1
Pavlov. Cond. response bias0.10.10.3-0.1-0.10.3-0.2-0.40.5-0.50.30.1
Conditioned reinforcement - actives0.40.30.9-0.4-0.6-0.40.60.1-0.20.8-0.9-0.7
Conditioned reinforcement - inactives1.01.22.4-0.9-1.2-1.01.0-0.40.11.1-1.6-1.6
Conditioned locomotion0.10.10.20.20.10.20.10.3-0.40.4-0.40.1
Intermittent access intake day 1-15 change0.50.51.2-0.4-0.7-1.00.70.3-0.40.1-1.1-0.8
Intermittent access intake escalation0.30.30.70.1-0.1-0.70.40.8-0.8-0.2-0.8-0.2
Intermittent access intake escalation 21.21.24.01.10.9-0.40.02.0-1.8-0.5-0.40.8
Intermitt. access day 1 inactive lever presses0.40.41.2-0.10.0-0.50.41.1-1.10.9-0.4-0.0
Intermitt. access day 15 inactive lever presses2.32.63.7-1.4-1.8-1.91.80.7-1.01.9-1.8-1.7
Intermitt. access escalation Index2.42.13.91.01.52.0-1.7-0.71.1-1.41.61.7
Intermittent access day 1 total infusions0.50.61.10.60.51.1-0.9-0.80.9-0.70.60.5
Intermittent access day 15 total infusions0.10.20.30.60.20.5-0.4-0.40.5-0.60.00.1
Intermittent access terminal intake (last 3 days)0.10.10.30.0-0.2-0.10.0-0.20.10.1-0.5-0.3
Intermittent access total infusions0.10.10.20.3-0.00.4-0.2-0.50.4-0.20.0-0.0
Intermittent access day 1 locomotion0.40.40.91.00.70.8-0.60.3-0.1-0.60.10.7
Intermittent access day 15 total locomotion0.80.82.10.3-0.2-0.90.91.4-1.40.2-1.2-0.4
Intermittent access total locomotion0.50.51.40.4-0.1-0.70.61.2-1.2-0.0-1.0-0.3
Intermittent access standard deviation2.12.33.8-1.4-1.8-1.81.60.0-0.41.5-1.9-1.8
Cocaine induced anxiety2.73.15.22.32.21.7-1.70.6-0.2-2.01.82.1
Post-drug Anxiety0.91.02.01.21.20.9-0.90.5-0.3-0.81.31.4
Baseline Anxiety0.40.41.0-0.7-0.7-0.30.2-0.90.71.0-0.2-0.5
Lifetime Intake0.10.10.10.4-0.00.4-0.2-0.30.3-0.0-0.1-0.0
Incentive Sensitization - Responses0.70.71.10.60.70.9-0.9-0.70.8-1.11.00.6
Incentive Sensitization - Breakpoint0.80.81.50.70.81.0-1.0-0.70.8-1.21.10.7
Progressive ratio test 1 active lever presses0.20.20.60.30.40.7-0.6-0.40.5-0.30.30.2
Progressive ratio test 1 breakpoint0.20.20.50.30.30.7-0.5-0.50.5-0.20.20.1
Progressive ratio test 1 inactive lever presses0.30.31.20.1-0.30.1-0.2-1.11.0-0.0-0.0-0.4
Progressive ratio test 2 active lever presses0.80.81.40.70.71.2-1.0-0.91.0-1.01.00.5
Progressive ratio test 2 breakpoint1.31.42.20.90.91.5-1.3-1.21.3-1.51.30.7
Progressive ratio test 2 inactive lever presses0.20.30.7-0.1-0.4-0.40.50.5-0.60.5-0.8-0.6
Total sessions with >9 infusions0.00.00.10.1-0.20.20.1-0.0-0.10.2-0.3-0.1
Short access day 1 total inactive lever presses0.80.83.00.90.5-0.30.21.7-1.60.4-0.60.4
Short access day 10 total inactive lever presses0.20.20.70.30.3-0.30.10.8-0.80.1-0.20.3
Short access day 1 total infusions0.30.30.80.70.60.9-0.7-0.20.3-0.20.30.6
Short access day 10 total infusions0.00.00.20.1-0.20.00.1-0.0-0.00.4-0.3-0.3
Short access total infusions0.10.10.30.2-0.20.10.2-0.0-0.10.5-0.4-0.3
Short access day 1 locomotion3.33.55.02.22.02.1-2.2-0.71.0-1.72.12.0
Short access day 10 total locomotion0.60.72.40.90.5-0.30.11.5-1.40.6-0.30.5
Short access total locomotion0.30.31.31.20.60.6-0.40.4-0.30.10.20.6
Compulsive drug intake2.52.54.51.51.62.1-1.8-0.50.8-1.22.01.9
One hour access (0.3 mA shock)0.60.71.41.00.91.2-1.0-0.40.5-1.00.50.8
One hour access (shock baseline)0.40.41.2-0.3-0.4-0.70.70.7-0.80.2-1.1-0.6
Number of responses in last shaping day0.30.31.00.1-0.1-0.30.40.6-0.71.0-0.5-0.2
Context. condit. distance diff. score5.66.812.73.23.62.6-2.50.9-0.1-2.32.63.5
Locomotion velocity, session 10.20.30.50.50.70.4-0.30.5-0.3-0.50.40.7
Locomotion distance, session 10.60.81.90.1-0.01.0-0.8-1.41.4-1.00.80.0
Locomotion velocity, session 20.10.10.30.10.30.00.00.5-0.40.10.00.3
Locomotion distance, session 20.30.51.00.50.40.9-0.7-0.60.7-1.00.80.5
Locomotion velocity, session 30.20.20.6-0.7-0.50.00.1-0.80.7-0.0-0.1-0.6
Locomotion distance, session 31.51.72.61.21.11.5-1.5-0.91.1-1.61.41.1
Stereotopy head waving bouts, day 31.72.03.9-0.4-0.7-1.61.61.9-2.01.5-1.6-0.7
Stereotopy head waving duration, day 31.21.42.4-0.4-0.8-1.31.41.4-1.51.2-1.4-0.7
Locomotion velocity, session 74.24.66.32.42.22.4-2.4-0.91.4-2.52.42.2
Locomotion distance, session 73.84.86.62.11.92.5-2.5-1.62.0-2.62.51.9
Stereotopy head waving bouts, day 72.02.23.1-1.8-1.4-1.61.70.8-1.11.7-1.7-1.4
Stereotopy head waving duration, day 72.53.14.1-1.8-1.6-2.02.01.2-1.51.9-2.0-1.6
Locomotion velocity, session 81.82.17.01.41.5-0.10.22.6-2.30.3-0.11.5
Locomotion distance, session 83.14.68.02.62.82.3-2.10.50.1-2.12.12.8
Degree of sensitization distance0.40.40.80.90.90.5-0.50.6-0.4-0.30.50.9
Degree of sensitization stereotypy1.31.42.5-1.6-1.1-1.31.30.5-0.71.4-1.3-1.1
Condit. Reinf. active minus inactive responses0.91.11.91.40.91.2-1.0-0.30.5-1.41.01.0
Condit. Reinf. active-inactive response ratio0.10.10.30.0-0.30.2-0.0-0.50.4-0.10.0-0.3
Condit. Reinf. active responses1.51.83.61.51.31.5-1.4-0.70.9-1.91.31.1
Condit. Reinf. inactive responses2.22.64.91.11.31.6-1.7-1.61.8-2.21.71.1
Incentive salience index mean1.92.35.62.41.81.4-1.30.5-0.2-1.81.31.8
Condit. Reinf. lever presses2.94.08.12.82.51.7-1.70.9-0.3-2.21.72.5
Time in familiar zone, hab. session 13.53.36.90.40.61.9-2.0-2.52.6-1.92.00.7
Time in novel zone, hab. session 12.01.94.7-0.2-0.2-1.31.42.1-2.21.4-1.4-0.3
Total zone transitions, hab. session 10.60.81.30.80.81.1-1.0-0.70.8-1.01.00.8
Total locomotion distance, hab. session 10.50.71.20.60.61.1-1.0-0.80.9-1.00.90.6
Locomotion velocity, hab. session 10.30.40.80.30.10.8-0.6-0.90.9-0.60.60.1
Time in familiar zone, hab. session 20.30.40.9-0.40.00.5-0.6-0.90.9-0.50.60.1
Time in novel zone, hab. session 20.20.20.4-0.0-0.3-0.60.60.5-0.60.4-0.6-0.4
Total zone transitions, hab. session 20.10.20.5-0.7-0.20.2-0.1-0.60.6-0.10.1-0.3
Total locomotion distance, hab. session 21.01.32.10.50.81.4-1.3-1.11.3-1.41.30.8
Locomotion velocity, hab. session 21.01.42.30.60.91.5-1.4-1.11.2-1.41.40.9
Novel to familiar place preference ratio0.10.10.2-0.0-0.30.10.0-0.50.40.1-0.0-0.3
Novelty place preference0.10.10.2-0.1-0.4-0.10.3-0.20.10.3-0.3-0.4
Time in novel zone, NPP test0.10.10.3-0.2-0.5-0.30.4-0.0-0.10.4-0.4-0.5
Total zone transitions, NPP test1.11.62.71.01.11.6-1.4-0.81.0-1.61.41.1
Total locomotion distance, NPP test1.21.62.50.80.81.6-1.4-1.41.5-1.61.40.8
Locomotion velocity, NPP test1.92.84.21.21.12.1-1.9-1.71.9-1.91.81.1
Pavlov. Cond. lever latency1.82.34.9-2.2-2.0-0.70.7-1.81.41.1-0.6-1.9
Pavlov. Cond. magazine entry latency1.72.34.41.92.10.9-0.91.7-1.2-1.30.82.0
Pavlov. Cond. change in total contacts1.01.13.70.60.4-0.80.81.9-1.80.3-0.80.2
Pavlov. Cond. index score2.32.96.02.52.30.9-0.92.0-1.5-1.20.82.2
Pavlov. Cond. latency score1.92.45.12.22.00.6-0.62.1-1.7-0.90.51.9
Pavlov. Cond. lever contacts1.41.74.01.91.60.2-0.22.0-1.7-0.60.21.4
Pavlov. Cond. magazine entry number2.02.54.9-2.1-2.2-1.31.3-1.00.61.7-1.3-2.1
Pavlov. Cond. intertrial magazine entries1.01.24.00.1-0.30.7-0.8-2.01.9-1.00.9-0.3
Pavlov. Cond. lever-magazine prob. diff.2.43.06.22.52.41.0-1.01.9-1.4-1.30.92.3
Pavlov. Cond. response bias2.43.05.72.42.41.1-1.11.6-1.2-1.61.12.3
Bone: apparent density1.52.53.91.40.81.7-1.7-1.82.0-1.91.70.9
Bone surface0.10.30.60.5-0.2-0.50.50.8-0.80.2-0.5-0.1
Bone volume0.00.10.20.1-0.5-0.30.3-0.20.1-0.0-0.3-0.4
Bone: connectivity density2.64.15.92.31.82.2-2.2-1.21.6-2.42.21.9
Bone: cortical apparent density0.91.22.3-1.4-1.5-0.50.5-1.41.10.4-0.6-1.5
Bone: cortical area1.82.84.1-0.9-1.9-2.02.00.9-1.31.7-2.0-1.8
Bone: cortical porosity0.60.61.0-0.9-1.0-0.80.7-0.30.00.9-0.8-1.0
Bone: cortical porosity0.70.71.2-0.3-0.6-1.01.00.8-0.91.1-1.0-0.6
Bone: cortical thickness3.15.110.7-2.3-3.3-2.12.2-1.30.61.9-2.2-3.2
Bone: cortical thickness1.21.42.8-1.2-1.7-0.60.6-1.71.30.4-0.6-1.7
Bone: cortical tissue density0.70.91.8-1.2-1.4-0.50.4-1.31.00.3-0.5-1.3
Bone: elastic displacement0.30.41.0-1.0-0.7-0.20.2-0.80.60.3-0.2-0.7
Bone: elastic work1.62.13.1-1.5-1.7-1.71.60.2-0.61.5-1.7-1.8
Bone: endosteal estimation3.16.719.50.1-0.2-2.42.44.4-4.42.2-2.3-0.2
Bone: endosteal perimeter1.63.212.01.51.4-0.50.53.5-3.10.4-0.41.4
Bone: final force5.28.512.6-3.1-3.5-3.33.30.4-1.12.9-3.3-3.6
Bone: final moment4.67.611.2-2.9-3.3-3.23.20.5-1.22.6-3.1-3.3
Bone: marrow area3.16.619.00.1-0.2-2.42.44.4-4.32.2-2.3-0.2
Bone: maximum diameter1.12.06.90.80.2-1.11.12.6-2.50.9-1.10.3
Bone: maximum force4.37.410.3-2.6-3.2-3.23.10.8-1.42.6-3.2-3.2
Bone: maximum moment3.96.79.5-2.4-3.0-3.13.00.9-1.52.4-3.1-3.0
Bone: minimum diameter1.42.68.71.10.3-1.21.23.0-2.81.0-1.10.3
Bone: periosteal estimation2.85.711.4-0.6-1.3-2.72.73.2-3.42.4-2.6-1.2
Bone: periosteal perimeter1.52.56.50.1-0.4-1.61.62.5-2.51.4-1.5-0.3
Bone: post-yield work0.70.92.81.10.9-0.10.11.7-1.5-0.7-0.10.9
Bone: stiffness1.01.63.1-1.4-1.8-1.41.4-0.2-0.20.8-1.4-1.7
Bone: tissue strength4.03.85.1-2.3-2.2-2.22.20.4-0.92.0-2.2-2.2
Bone: trabecular number1.72.74.51.30.71.7-1.7-2.02.1-2.01.70.8
Bone: trabecular spacing4.05.27.5-2.2-1.7-2.52.62.0-2.32.7-2.6-1.7
Bone: trabecular thickness1.21.52.21.00.71.2-1.3-1.41.5-1.51.40.7
Bone: trabecular tissue density1.82.53.7-1.8-1.7-1.71.70.6-0.91.9-1.6-1.7
Breakpoint value in progressive ratio session0.91.01.71.11.01.1-1.2-0.50.7-0.81.30.9
Distance traveled before self-admin0.30.30.80.60.6-0.10.20.9-0.8-0.3-0.10.5
Distance traveled after self-admin0.40.41.2-0.20.4-0.90.41.1-1.10.3-0.1-0.1
Delta time in closed arm before/after self-admin0.20.20.8-0.2-0.5-0.60.50.2-0.30.9-0.4-0.4
Delta time in open arm before/after self-admin0.00.00.1-0.2-0.0-0.1-0.1-0.20.2-0.4-0.1-0.2
Diff in mean of infusions in LGA sessions3.33.76.41.71.82.2-2.5-1.72.0-1.81.81.7
Extinction: sum of active levers before priming0.50.50.90.70.51.0-0.8-0.80.9-0.30.50.3
Active lever presses in extinction session 60.20.20.8-0.40.1-0.1-0.3-0.90.8-0.00.4-0.3
Delta distance traveled before/after self-admin0.90.92.0-1.3-0.7-1.40.70.5-0.71.0-1.0-1.1
Delta ambulatory time before/after self-admin0.40.40.8-0.7-0.2-0.90.40.8-0.80.7-0.6-0.4
Time in closed arm before self-admin0.00.00.1-0.0-0.00.20.0-0.20.20.10.40.0
Time in closed arm after self-admin0.80.81.6-1.0-1.0-0.80.9-0.40.11.3-0.9-1.1
Time in open arm before self-admin0.50.50.80.80.90.5-0.60.7-0.5-0.8-0.10.9
Time in open arm after self-admin0.80.91.91.01.30.9-1.20.3-0.1-1.40.51.1
Sum of active levers in priming session hrs 5-60.30.30.60.60.60.7-0.8-0.50.6-0.20.30.4
Time to tail flick, vehicle, before self-admin0.20.20.40.50.50.2-0.20.5-0.3-0.60.30.5
Time to tail flick, vehicle, after self-admin1.01.12.31.41.20.5-0.71.0-0.7-0.80.91.5
Time to tail flick, test, before self-admin0.10.10.2-0.5-0.3-0.10.2-0.50.40.0-0.2-0.4
Time to tail flick, test, after self-admin1.41.43.91.51.40.9-1.00.6-0.2-2.00.71.4
Delta time to tail flick, vehicle, before/after SA0.60.51.00.80.70.8-0.7-0.20.4-0.81.01.0
Delta time to tail flick, test, before/after SA1.21.12.71.20.91.0-1.2-0.30.5-1.70.91.1
Ambulatory time before self-admin0.10.10.10.30.1-0.20.30.4-0.4-0.2-0.4-0.1
Ambulatory time after self-admin0.30.31.0-0.10.4-0.70.21.0-1.00.2-0.2-0.0
Total heroin consumption0.00.10.20.5-0.0-0.0-0.10.00.0-0.4-0.4-0.0
Area under the delay curve1.71.83.1-1.3-1.3-1.61.30.2-0.51.7-1.6-1.6
Delay disc. indifference point, 0s delay0.40.40.8-0.1-0.2-0.60.80.8-0.90.8-0.7-0.5
Delay disc. indifference point, 16s delay1.61.73.4-1.5-1.4-1.20.7-1.30.91.2-1.3-1.8
Delay disc. indifference point, 2s delay2.12.44.8-1.2-1.2-1.61.81.2-1.42.2-1.7-1.3
Delay disc. indifference point, 24s delay0.60.50.9-0.9-0.9-0.90.4-0.40.20.9-0.7-0.9
Delay disc. indifference point, 4s delay2.52.63.9-1.1-0.9-1.91.81.5-1.71.7-2.0-1.5
Delay disc. indifference point, 8s delay0.30.30.6-0.5-0.5-0.60.3-0.0-0.10.7-0.7-0.8
Delay discount exponential model param1.71.83.11.41.31.6-1.3-0.20.5-1.81.61.6
Delay discount hyperbolic model param1.81.93.31.31.21.6-1.4-0.40.7-1.81.61.5
Fecal boli incidents, locomotor time 10.60.61.30.70.51.1-0.8-0.50.6-0.81.10.9
Change in fecal boli incidents, locomotor task0.80.82.5-0.6-0.5-1.10.60.7-0.81.6-0.9-0.5
Time >=10cm from walls, locomotor time 10.90.92.5-0.20.1-0.80.91.6-1.60.9-0.70.1
Bouts of movement, locomotor time 11.41.53.01.71.51.0-1.10.4-0.1-1.61.21.4
Total resting periods, locomotor time 10.91.02.21.51.40.6-0.80.7-0.4-1.20.81.0
Rest time, locomotor task time 10.50.62.10.80.6-0.20.01.5-1.3-0.50.20.6
Distance moved, locomotor task time 10.70.71.4-1.2-1.0-0.70.9-0.40.21.0-0.9-1.0
Vertical activity count, locomotor time 10.50.51.1-1.0-1.0-0.30.9-0.50.30.7-0.7-0.7
Time >=10cm from walls, locomotor time 20.30.30.8-0.00.20.00.50.9-0.90.7-0.20.4
Bouts of movement, locomotor time 21.01.03.7-0.1-0.1-0.70.81.9-1.80.4-1.0-0.1
Total resting periods, locomotor time 21.11.14.70.30.3-0.50.52.2-2.00.2-0.70.3
Rest time, locomotor task time 21.61.95.71.51.4-0.0-0.12.4-2.0-0.80.21.5
Distance moved, locomotor task time 20.91.12.0-1.4-1.1-0.30.8-1.31.01.0-0.7-1.2
Vertical activity count, locomotor time 20.30.31.1-0.7-0.50.20.2-1.10.90.4-0.0-0.4
Weight adjusted by age3.13.44.5-1.6-1.6-1.82.11.7-1.92.1-2.1-1.7
Seeking ratio, delayed vs. immediate footshock0.40.51.0-0.6-0.8-0.71.00.5-0.60.5-0.8-0.7
Locomotion in novel chamber0.50.61.0-0.7-0.6-1.00.70.5-0.70.7-1.0-0.8
Locomotion in novel chamber post-restriction0.60.71.1-1.0-1.0-1.01.0-0.1-0.10.8-0.7-1.0
Progressive ratio4.45.17.0-2.5-2.6-2.52.60.7-1.22.3-2.5-2.6
Food seeking constrained by brief footshock0.00.00.0-0.10.10.1-0.1-0.10.1-0.1-0.10.1
Seeking ratio, punishment vs. effort3.64.46.02.22.42.4-2.4-0.71.2-2.02.42.4
Run reversals in cocaine runway, females0.40.41.3-0.6-0.7-0.10.1-1.11.0-0.0-0.1-0.8
Run reversals in cocaine runway, males1.51.45.3-0.10.2-0.60.92.3-2.20.3-1.20.3
Latency to leave start box in cocaine runway0.20.20.8-0.4-0.4-0.10.10.1-0.10.9-0.5-0.3
Latency to leave start box in cocaine runway, F0.20.20.40.50.60.6-0.5-0.00.1-0.10.30.7
Latency to leave start box in cocaine runway, M1.71.63.0-1.6-1.6-1.21.1-0.1-0.21.6-1.3-1.7
Cd content in liver0.60.61.6-0.8-1.2-0.70.6-0.70.50.2-0.6-1.2
Co content in liver1.61.83.4-1.7-1.8-1.21.1-0.90.51.5-1.2-1.9
Cu content in liver3.33.98.20.61.02.3-2.2-2.72.9-1.62.20.9
Fe content in liver0.70.82.3-1.5-1.1-0.80.5-0.70.50.8-0.6-1.1
K content in liver0.10.10.50.70.30.3-0.4-0.20.2-0.10.40.3
Mg content in liver2.52.66.12.52.11.5-1.50.8-0.4-1.21.52.0
Mn content in liver2.63.05.72.32.31.0-0.82.4-1.9-0.60.82.2
Na content in liver0.10.10.2-0.3-0.5-0.10.2-0.40.30.2-0.2-0.5
Rb content in liver0.81.01.51.20.90.9-1.2-0.60.8-1.01.21.0
Se content in liver2.02.45.02.22.00.7-0.82.1-1.6-0.60.81.9
Sr content in liver0.70.61.8-0.4-0.2-0.60.71.3-1.30.7-0.8-0.4
Zn content in liver0.10.10.20.20.30.3-0.10.3-0.30.5-0.00.2