Coq10b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000014456 0.05 0.03 4.2e-05 0.03 0.03 0.03 0.03 1.6e-04 1.7e-04 3.4e-04 2.6e-04
2 Adipose mRNA stability ENSRNOG00000014456 0.02 0.02 3.3e-03 0.01 0.02 0.02 0.01 1.1e-02 2.3e-03 6.4e-03 9.4e-03
3 BLA gene expression ENSRNOG00000014456 0.05 0.04 4.8e-03 0.03 0.03 0.03 0.03 6.9e-03 1.6e-02 8.1e-03 9.9e-03
4 Brain gene expression ENSRNOG00000014456 0.14 0.07 1.1e-15 0.17 0.16 0.18 0.17 2.0e-15 1.0e-14 4.3e-16 1.6e-15
5 Brain mRNA stability ENSRNOG00000014456 0.05 0.03 3.6e-05 0.04 0.03 0.03 0.04 3.1e-04 1.4e-03 1.7e-03 2.7e-04
6 LHb gene expression ENSRNOG00000014456 0.6 0.31 1.5e-04 0.06 0.05 0.01 0.05 1.6e-02 2.3e-02 1.9e-01 2.8e-02
7 Liver mRNA stability ENSRNOG00000014456 0.03 0.02 1.6e-03 0.02 0.01 0.01 0.01 5.8e-03 2.2e-02 2.4e-02 1.7e-02
8 NAcc gene expression ENSRNOG00000014456 0.18 0.12 1.7e-06 0.06 0.07 0.07 0.07 2.9e-05 6.2e-06 3.9e-06 5.1e-06
9 NAcc mRNA stability ENSRNOG00000014456 0.11 0.07 4.8e-07 0.08 0.05 0.08 0.07 9.5e-07 2.2e-04 1.8e-06 6.3e-06
10 PL gene expression ENSRNOG00000014456 0.07 0.05 5.0e-06 0.04 0.04 0.05 0.05 3.0e-04 8.0e-04 1.3e-04 9.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail4.012.814.23.73.83.43.63.83.63.23.43.63.7
BMI without tail0.10.20.90.30.3-0.3-0.20.6-0.21.0-0.60.4-0.2
Body weight1.04.46.0-1.8-2.1-2.5-2.4-1.6-2.2-2.1-2.1-1.7-2.1
Epididymis fat weight1.74.15.9-1.7-2.1-2.1-2.4-1.4-2.2-2.1-2.1-1.5-2.3
Glucose0.30.51.81.10.50.2-0.31.30.20.3-0.21.3-0.1
Heart weight0.20.20.90.20.20.20.60.20.6-0.30.90.10.7
Left kidney weight0.10.30.8-0.6-0.7-0.4-0.5-0.6-0.5-0.9-0.2-0.7-0.4
Right kidney weight0.10.30.6-0.7-0.6-0.6-0.3-0.8-0.4-0.8-0.2-0.8-0.3
Tail length12.236.843.7-5.7-6.2-6.5-6.6-5.5-6.4-4.9-6.5-5.5-6.6
Length with tail12.244.650.3-6.5-6.9-6.9-7.1-6.3-7.0-5.9-6.7-6.3-7.0
Length without tail1.22.74.5-1.7-1.8-1.5-1.6-1.6-1.5-2.1-1.2-1.6-1.4
Liver weight, left1.62.53.2-1.8-1.7-1.7-1.4-1.8-1.5-1.5-1.3-1.8-1.4
Liver weight, right1.22.02.5-1.6-1.5-1.0-1.4-1.5-1.5-1.2-1.3-1.6-1.3
Parametrial fat weight0.00.00.00.1-0.00.0-0.00.0-0.0-0.10.00.1-0.1
Retroperitoneal fat weight0.10.21.00.2-0.3-0.4-0.60.3-0.2-1.0-0.10.3-0.4
Intraocular pressure3.44.96.12.32.32.52.12.32.22.11.92.32.1
Extensor digitorum longus weight1.56.19.22.82.72.41.83.02.13.01.43.01.8
Soleus weight0.10.20.7-0.6-0.5-0.4-0.2-0.6-0.3-0.9-0.0-0.6-0.2
Tibialis anterior weight0.41.52.91.41.41.11.01.41.11.70.71.40.9
Tibia length6.618.721.8-4.3-4.4-4.5-4.6-4.1-4.6-3.2-4.6-4.1-4.7
Number of licking bursts0.80.91.50.80.91.21.10.71.10.41.20.71.1
Food consumed during 24 hour testing period0.10.10.2-0.2-0.3-0.4-0.5-0.1-0.3-0.4-0.4-0.1-0.4
Times rat made contact with spout0.10.10.4-0.1-0.2-0.3-0.50.0-0.40.2-0.60.0-0.5
Mean time between licks in bursts0.20.31.00.60.50.3-0.10.80.11.0-0.30.8-0.1
Mean num. licks in bursts0.50.61.2-0.6-0.6-1.0-0.9-0.4-0.9-0.2-1.1-0.4-0.9
Std. dev. time between licks in bursts3.54.15.52.32.12.21.72.32.11.41.92.31.9
Water consumed over 24 hours0.81.01.30.91.01.21.10.81.00.71.00.81.1
Indifference point 0 sec1.21.94.10.81.21.41.90.41.60.62.00.51.9
Indifference point AUC0.10.10.2-0.5-0.4-0.1-0.3-0.4-0.4-0.3-0.4-0.4-0.3
Indifference point function ln k1.62.34.11.21.41.61.91.01.80.92.01.01.8
Indifference point function log k1.62.34.11.21.41.61.91.01.80.92.01.01.8
Delay discounting total patch changes 0 sec1.42.24.71.01.31.52.00.61.80.62.20.82.0
Delay discounting total patch changes 12 sec0.60.82.10.50.60.91.20.21.1-0.21.40.41.2
Delay discounting total patch changes 18 sec2.02.73.91.31.71.72.01.21.72.01.61.31.8
Delay discounting total patch changes 24 sec0.00.00.0-0.1-0.0-0.10.1-0.1-0.00.0-0.0-0.10.0
Delay discounting total patch changes 6 sec0.40.61.30.40.71.11.10.10.80.41.10.21.0
Delay discounting time to switch 0 sec0.40.51.6-0.2-0.4-0.8-0.9-0.1-0.90.4-1.3-0.1-1.1
Delay discounting water rate 0 sec0.10.10.6-0.1-0.20.20.1-0.10.1-0.70.4-0.20.2
Delay discounting water rate 12 sec1.11.74.30.60.81.61.70.41.5-0.12.10.41.8
Delay discounting water rate 18 sec0.30.32.2-0.3-0.4-0.00.1-0.40.1-1.50.7-0.40.3
Delay discounting water rate 24 sec0.10.10.2-0.2-0.3-0.2-0.4-0.2-0.40.0-0.5-0.2-0.5
Delay discounting water rate 6 sec0.10.10.50.20.10.20.20.30.4-0.70.60.30.4
Locomotor activity0.10.20.5-0.3-0.5-0.5-0.4-0.3-0.4-0.7-0.2-0.4-0.3
Locomotor testing distance0.10.10.40.00.10.20.4-0.10.3-0.50.7-0.10.5
Locomotor testing rearing0.20.40.5-0.5-0.6-0.6-0.7-0.5-0.7-0.7-0.6-0.5-0.6
Light reinforcement 12.34.26.92.52.11.31.72.52.20.82.22.61.9
Light reinforcement 20.40.51.70.40.20.30.60.10.8-1.21.30.30.8
Reaction time number correct0.60.81.30.80.90.91.10.71.10.51.20.81.0
Reaction time mean minus median0.91.22.3-0.6-1.0-1.5-1.5-0.4-1.1-1.3-1.2-0.4-1.3
Reaction time mean minus median AUC0.50.61.6-0.4-0.7-1.2-1.0-0.3-0.7-0.9-0.7-0.4-0.9
Reaction time num false alarms3.34.55.82.22.22.21.82.32.12.31.62.41.8
Reaction time num false alarms AUC3.54.96.82.42.42.21.92.52.12.61.62.61.8
Reaction time trials correct on left0.60.81.30.80.90.91.10.71.10.51.20.81.0
Reaction time trials on left0.50.71.10.80.80.81.00.71.00.51.10.71.0
Reaction time mean2.33.24.6-1.5-1.8-2.1-2.2-1.3-1.9-1.6-2.0-1.3-2.1
Reaction time mean AUC1.92.54.0-1.2-1.6-2.0-2.0-1.0-1.6-1.4-1.8-1.0-1.9
Median of all reaction times2.12.93.9-1.5-1.7-1.9-2.0-1.3-1.8-1.4-1.9-1.3-1.9
Reaction time omissions0.60.81.5-0.6-0.9-1.0-1.2-0.4-0.9-1.2-0.9-0.5-1.0
Reaction time false alarm rate1.52.13.71.61.61.41.11.71.31.90.81.81.0
Reaction time premature initiation rate3.34.49.01.51.82.32.71.32.50.53.01.22.8
Reaction time premature initiations4.25.911.31.92.22.73.01.62.80.83.41.63.1
Std. dev. reaction times1.92.63.7-1.4-1.7-1.8-1.9-1.2-1.6-1.8-1.6-1.3-1.8
Reaction time trials completed0.50.71.10.80.80.81.00.71.00.51.10.71.0
Reaction time trials AUC0.50.71.10.80.90.81.00.81.00.51.00.80.9
Social response proportion4.04.37.2-2.1-2.2-2.1-1.9-2.2-1.9-2.7-1.5-2.1-1.9
Social responses1.41.84.3-0.9-1.3-1.4-1.6-0.9-1.3-2.1-1.1-0.8-1.5
Social time0.50.71.5-0.4-0.8-1.2-1.1-0.2-0.7-1.1-0.8-0.3-0.9
Conditioned locomotion1.21.44.1-1.0-1.3-1.3-1.1-1.0-1.0-2.0-0.6-1.0-1.0
Cocaine response after cond. corrected1.41.53.2-1.5-1.3-1.2-0.3-1.8-0.7-1.7-0.0-1.8-0.4
Cocaine response after cond. not corrected2.32.55.0-2.0-1.7-1.6-0.8-2.2-1.2-1.8-0.5-2.2-0.8
Cocaine response before conditioning0.00.10.30.10.10.2-0.10.2-0.10.5-0.30.2-0.1
Saline control response0.10.20.50.60.40.40.00.70.30.30.00.70.1
Condit. Reinf. active minus inactive responses2.83.58.8-2.1-2.1-1.4-1.2-2.3-1.4-3.0-0.6-2.3-1.1
Condit. Reinf. active-inactive response ratio0.60.62.5-0.8-0.7-0.30.0-1.0-0.2-1.60.5-1.00.1
Condit. Reinf. active responses1.42.06.7-1.6-1.5-0.7-0.7-1.8-0.8-2.6-0.0-1.8-0.5
Condit. Reinf. inactive responses0.20.20.4-0.6-0.5-0.1-0.2-0.6-0.3-0.6-0.1-0.7-0.2
Condit. Reinf. lever presses0.81.12.90.40.61.31.40.21.1-0.31.70.11.5
Condit. Reinf. lever reinforcers received1.31.86.2-1.5-1.4-0.5-0.5-1.7-0.7-2.50.2-1.8-0.3
Pavlov. Cond. lever latency0.71.02.2-0.4-0.8-1.5-1.4-0.2-1.0-0.6-1.3-0.2-1.3
Pavlov. Cond. magazine entry latency0.10.21.10.10.40.50.30.10.11.0-0.10.10.2
Pavlov. Cond. change in total contacts0.50.81.80.10.51.21.3-0.20.90.11.3-0.21.3
Pavlov. Cond. index score0.50.61.50.20.61.21.10.10.80.51.00.01.0
Pavlov. Cond. latency score0.30.41.10.20.51.10.90.00.60.40.90.00.9
Pavlov. Cond. lever contacts0.60.82.00.20.51.41.3-0.10.90.11.4-0.11.3
Pavlov. Cond. magazine entry number0.10.10.30.50.3-0.10.10.50.30.20.20.60.2
Pavlov. Cond. intertrial magazine entries0.10.20.40.40.20.20.30.40.4-0.50.60.40.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.60.20.61.31.10.10.80.51.00.11.1
Pavlov. Cond. response bias0.20.20.5-0.4-0.00.70.6-0.60.2-0.00.6-0.60.6
Conditioned reinforcement - actives0.20.20.60.0-0.1-0.6-0.60.1-0.40.4-0.80.2-0.6
Conditioned reinforcement - inactives0.10.20.4-0.4-0.3-0.3-0.4-0.2-0.50.0-0.6-0.4-0.4
Conditioned locomotion0.60.71.10.90.70.80.70.90.9-0.01.00.90.8
Intermittent access intake day 1-15 change0.40.41.10.90.70.10.30.90.60.30.51.10.3
Intermittent access intake escalation0.30.30.90.80.60.00.30.80.50.20.50.90.3
Intermittent access intake escalation 20.10.10.40.0-0.2-0.6-0.3-0.1-0.1-0.5-0.10.1-0.3
Intermitt. access day 1 inactive lever presses1.01.12.91.31.10.80.51.70.71.00.41.40.8
Intermitt. access day 15 inactive lever presses0.10.10.20.30.3-0.00.20.40.20.30.10.30.2
Intermitt. access escalation Index1.00.91.9-0.4-0.8-1.1-1.4-0.1-1.1-0.7-1.3-0.1-1.2
Intermittent access day 1 total infusions0.80.92.2-0.7-1.0-1.0-1.1-0.6-0.8-1.5-0.7-0.6-0.9
Intermittent access day 15 total infusions0.30.41.30.1-0.4-0.9-0.80.1-0.4-1.1-0.40.2-0.6
Intermittent access terminal intake (last 3 days)0.20.21.10.2-0.2-0.6-0.40.2-0.1-1.00.00.3-0.3
Intermittent access total infusions0.70.72.4-0.4-0.8-1.1-1.1-0.3-0.7-1.5-0.6-0.3-0.9
Intermittent access day 1 locomotion0.00.00.10.20.10.20.00.30.2-0.40.20.20.2
Intermittent access day 15 total locomotion0.50.51.7-0.6-0.8-0.9-0.7-0.7-0.5-1.3-0.3-0.6-0.6
Intermittent access total locomotion0.20.20.9-0.2-0.4-0.6-0.5-0.1-0.3-0.9-0.2-0.1-0.4
Intermittent access standard deviation0.40.41.31.00.5-0.10.21.00.5-0.20.51.10.3
Cocaine induced anxiety0.10.10.30.50.40.10.30.40.40.10.40.60.3
Post-drug Anxiety0.10.10.30.10.20.40.40.10.3-0.10.5-0.00.5
Baseline Anxiety0.20.20.7-0.7-0.5-0.1-0.2-0.7-0.4-0.4-0.3-0.8-0.2
Lifetime Intake0.30.31.0-0.1-0.4-0.8-0.80.1-0.5-1.0-0.50.1-0.7
Incentive Sensitization - Responses1.11.12.7-0.7-0.9-1.6-1.2-0.7-1.1-0.5-1.2-0.6-1.3
Incentive Sensitization - Breakpoint0.90.92.5-0.6-0.8-1.6-1.1-0.6-1.0-0.4-1.1-0.5-1.2
Progressive ratio test 1 active lever presses0.20.20.6-0.0-0.3-0.3-0.80.2-0.5-0.2-0.80.1-0.7
Progressive ratio test 1 breakpoint0.20.20.6-0.1-0.3-0.3-0.80.0-0.5-0.3-0.70.0-0.7
Progressive ratio test 1 inactive lever presses1.41.54.71.61.10.1-0.42.20.11.3-0.62.1-0.3
Progressive ratio test 2 active lever presses0.60.71.5-0.3-0.6-1.2-1.1-0.2-0.9-0.2-1.2-0.1-1.2
Progressive ratio test 2 breakpoint0.10.20.50.2-0.0-0.7-0.50.3-0.3-0.0-0.50.4-0.5
Progressive ratio test 2 inactive lever presses0.10.20.60.50.3-0.3-0.30.80.00.2-0.20.7-0.2
Total sessions with >9 infusions0.60.71.81.10.90.40.21.30.60.90.21.30.2
Short access day 1 total inactive lever presses0.40.51.10.50.30.80.60.60.7-0.91.00.40.9
Short access day 10 total inactive lever presses0.10.10.30.30.20.00.10.60.10.20.10.30.3
Short access day 1 total infusions0.10.10.50.60.3-0.1-0.10.70.2-0.30.10.70.0
Short access day 10 total infusions0.40.42.4-0.3-0.6-0.7-0.6-0.4-0.3-1.6-0.0-0.3-0.4
Short access total infusions0.10.10.40.50.3-0.0-0.00.60.3-0.40.20.60.1
Short access day 1 locomotion0.10.10.40.50.30.2-0.20.60.10.4-0.30.6-0.2
Short access day 10 total locomotion0.30.30.90.30.20.20.60.20.7-0.61.00.10.7
Short access total locomotion0.20.20.5-0.2-0.4-0.5-0.7-0.1-0.5-0.4-0.7-0.1-0.6
Compulsive drug intake0.10.10.40.20.30.60.30.20.20.50.20.20.3
One hour access (0.3 mA shock)0.20.21.8-0.0-0.3-0.4-0.3-0.20.0-1.30.2-0.0-0.2
One hour access (shock baseline)0.70.83.5-0.5-0.9-1.3-0.9-0.6-0.5-1.9-0.2-0.5-0.7
Number of responses in last shaping day0.70.72.21.00.80.3-0.21.20.01.5-0.61.2-0.2
Context. condit. distance diff. score1.11.32.41.31.20.80.71.60.91.40.51.50.7
Locomotion velocity, session 10.91.03.50.71.10.91.10.60.81.90.60.60.9
Locomotion distance, session 10.10.21.10.40.50.00.30.30.21.00.00.30.2
Locomotion velocity, session 20.60.72.50.50.81.11.00.30.61.60.50.30.7
Locomotion distance, session 20.10.10.40.40.40.40.30.30.20.60.10.30.2
Locomotion velocity, session 30.20.30.70.0-0.2-0.5-0.70.0-0.50.3-0.90.1-0.8
Locomotion distance, session 30.00.00.10.20.1-0.3-0.10.20.00.3-0.10.3-0.1
Stereotopy head waving bouts, day 31.11.32.61.31.21.30.61.40.81.60.31.40.5
Stereotopy head waving duration, day 30.20.20.70.50.30.5-0.20.5-0.10.8-0.50.6-0.3
Locomotion velocity, session 70.60.72.70.40.80.71.00.30.61.70.50.20.8
Locomotion distance, session 70.00.10.10.10.20.20.30.10.20.40.20.00.4
Stereotopy head waving bouts, day 70.20.30.6-0.6-0.5-0.3-0.3-0.8-0.5-0.0-0.5-0.7-0.5
Stereotopy head waving duration, day 70.10.20.4-0.4-0.2-0.2-0.3-0.5-0.50.4-0.6-0.4-0.5
Locomotion velocity, session 80.60.71.60.40.80.71.30.20.91.20.90.21.1
Locomotion distance, session 80.91.32.91.31.30.70.91.41.01.70.51.40.8
Degree of sensitization distance0.10.10.2-0.3-0.20.40.3-0.30.1-0.40.4-0.50.4
Degree of sensitization stereotypy0.20.30.8-0.7-0.5-0.3-0.1-0.9-0.4-0.3-0.2-0.8-0.2
Condit. Reinf. active minus inactive responses0.20.31.3-0.3-0.3-0.20.3-0.40.2-1.10.7-0.40.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.00.10.4-0.30.2-0.30.5-0.30.4
Condit. Reinf. active responses0.60.83.5-0.9-0.9-0.6-0.2-1.0-0.3-1.90.4-1.0-0.1
Condit. Reinf. inactive responses0.20.31.6-0.5-0.5-0.4-0.2-0.5-0.2-1.30.2-0.6-0.1
Incentive salience index mean0.40.52.2-0.5-0.5-0.20.3-0.80.2-1.50.9-0.70.4
Condit. Reinf. lever presses0.30.51.9-0.7-0.7-0.4-0.2-0.8-0.2-1.40.2-0.8-0.1
Time in familiar zone, hab. session 10.20.20.5-0.1-0.1-0.1-0.40.0-0.40.7-0.70.1-0.5
Time in novel zone, hab. session 10.10.10.50.10.10.20.4-0.00.4-0.50.7-0.10.5
Total zone transitions, hab. session 10.10.10.4-0.10.20.40.6-0.30.20.50.4-0.30.5
Total locomotion distance, hab. session 10.20.20.6-0.4-0.20.00.3-0.60.1-0.80.6-0.60.4
Locomotion velocity, hab. session 10.30.41.2-0.6-0.6-0.6-0.3-0.8-0.4-1.1-0.1-0.8-0.3
Time in familiar zone, hab. session 21.41.51.71.21.31.21.31.11.21.11.21.11.3
Time in novel zone, hab. session 20.60.61.1-0.6-0.8-0.9-0.9-0.7-0.8-1.0-0.7-0.6-0.9
Total zone transitions, hab. session 20.20.30.8-0.2-0.3-0.8-0.7-0.3-0.60.3-0.9-0.2-0.8
Total locomotion distance, hab. session 20.60.81.4-0.6-0.8-1.2-1.1-0.6-1.0-0.6-1.1-0.6-1.1
Locomotion velocity, hab. session 20.91.22.1-0.8-1.0-1.5-1.3-0.8-1.3-0.6-1.4-0.8-1.4
Novel to familiar place preference ratio1.81.85.1-1.2-1.5-1.1-1.3-1.3-1.2-2.3-0.8-1.3-1.2
Novelty place preference1.92.04.9-1.3-1.5-1.2-1.4-1.3-1.2-2.2-0.9-1.3-1.2
Time in novel zone, NPP test1.41.54.4-1.1-1.3-1.0-1.1-1.2-1.0-2.1-0.6-1.2-1.0
Total zone transitions, NPP test0.10.20.20.50.50.30.40.40.40.40.30.40.4
Total locomotion distance, NPP test0.30.40.90.60.50.50.70.60.7-0.20.90.50.8
Locomotion velocity, NPP test0.20.30.50.60.50.30.50.60.6-0.10.70.60.6
Pavlov. Cond. lever latency0.30.42.10.60.50.0-0.20.8-0.11.4-0.70.7-0.2
Pavlov. Cond. magazine entry latency0.30.41.4-0.4-0.30.20.4-0.60.3-1.20.8-0.60.5
Pavlov. Cond. change in total contacts0.70.72.3-0.00.20.71.1-0.30.9-0.81.5-0.31.1
Pavlov. Cond. index score0.30.42.1-0.4-0.4-0.10.2-0.60.2-1.50.8-0.60.3
Pavlov. Cond. latency score0.50.63.0-0.7-0.7-0.30.1-0.9-0.0-1.70.6-0.90.2
Pavlov. Cond. lever contacts0.30.42.1-0.4-0.4-0.00.2-0.60.2-1.40.7-0.60.3
Pavlov. Cond. magazine entry number0.30.31.30.60.50.1-0.20.8-0.01.1-0.50.8-0.2
Pavlov. Cond. intertrial magazine entries1.11.31.9-1.0-1.2-1.4-1.3-0.9-1.2-1.2-1.1-0.9-1.2
Pavlov. Cond. lever-magazine prob. diff.0.30.31.4-0.2-0.20.20.5-0.40.4-1.20.9-0.40.5
Pavlov. Cond. response bias0.20.21.3-0.4-0.4-0.00.1-0.50.1-1.10.5-0.50.2
Bone: apparent density6.611.014.3-3.7-3.5-3.2-3.0-3.7-3.3-3.2-2.8-3.8-2.9
Bone surface6.411.314.1-3.7-3.6-3.3-3.0-3.7-3.3-3.2-2.8-3.8-3.0
Bone volume6.711.415.3-3.8-3.6-3.2-2.9-3.9-3.3-3.3-2.7-3.9-2.9
Bone: connectivity density3.25.17.2-2.6-2.4-2.2-1.9-2.6-2.2-2.1-1.8-2.7-1.9
Bone: cortical apparent density8.010.511.73.43.43.03.23.43.42.73.23.43.3
Bone: cortical area0.20.20.4-0.5-0.5-0.3-0.5-0.6-0.5-0.6-0.4-0.5-0.5
Bone: cortical porosity5.66.06.9-2.4-2.5-2.6-2.6-2.3-2.6-2.0-2.6-2.3-2.6
Bone: cortical porosity7.78.39.0-2.8-3.0-3.0-3.0-2.7-3.0-2.6-2.9-2.7-3.0
Bone: cortical thickness1.42.32.71.71.61.51.51.61.61.21.51.61.5
Bone: cortical thickness1.82.13.41.21.41.61.81.01.60.91.81.01.8
Bone: cortical tissue density8.210.611.83.43.43.03.23.43.42.73.23.43.3
Bone: elastic displacement0.80.92.00.80.80.91.10.61.10.01.40.71.2
Bone: elastic work0.81.12.1-1.1-1.1-1.0-0.8-1.2-0.8-1.4-0.5-1.2-0.8
Bone: endosteal estimation4.710.212.6-3.5-3.5-2.6-3.0-3.5-3.2-3.4-2.7-3.5-3.0
Bone: endosteal perimeter4.59.211.2-3.3-3.2-2.7-2.9-3.3-3.1-2.9-2.7-3.3-2.9
Bone: final force1.82.94.4-1.4-1.8-1.4-2.1-1.3-1.8-1.9-1.8-1.3-2.0
Bone: final moment1.32.23.5-1.1-1.6-1.2-1.9-1.0-1.6-1.7-1.6-1.0-1.7
Bone: marrow area4.49.511.8-3.3-3.3-2.5-2.9-3.4-3.0-3.3-2.6-3.4-2.9
Bone: maximum diameter0.91.62.3-1.4-1.3-1.3-1.1-1.5-1.2-1.3-1.0-1.4-1.1
Bone: maximum force2.95.16.4-2.1-2.4-1.8-2.5-2.0-2.4-2.4-2.2-2.0-2.4
Bone: maximum moment2.23.95.2-1.8-2.1-1.5-2.3-1.7-2.1-2.2-1.9-1.7-2.2
Bone: minimum diameter0.81.42.7-1.2-1.3-0.9-1.1-1.2-1.1-1.6-0.8-1.2-1.1
Bone: periosteal estimation2.96.07.2-2.6-2.7-2.0-2.3-2.7-2.4-2.7-2.0-2.6-2.3
Bone: periosteal perimeter2.13.44.6-2.0-2.0-1.5-1.7-2.0-1.8-2.1-1.5-2.0-1.7
Bone: post-yield work1.41.92.8-1.2-1.5-1.0-1.7-1.1-1.5-1.5-1.5-1.1-1.6
Bone: stiffness4.06.38.8-2.3-2.6-2.2-3.0-2.1-2.8-2.2-2.8-2.1-2.9
Bone: tissue strength1.61.53.4-0.8-1.0-1.4-1.7-0.5-1.4-0.4-1.8-0.5-1.7
Bone: trabecular number4.46.88.6-2.9-2.7-2.6-2.4-2.8-2.7-2.2-2.4-2.9-2.4
Bone: trabecular spacing0.50.71.20.70.91.00.80.80.71.10.60.70.8
Bone: trabecular thickness1.72.03.3-1.7-1.5-1.2-1.1-1.8-1.3-1.6-0.9-1.8-1.1
Bone: trabecular tissue density0.10.20.50.60.40.2-0.10.70.20.5-0.10.7-0.0
Breakpoint value in progressive ratio session0.00.10.20.1-0.1-0.10.10.10.2-0.50.40.10.2
Distance traveled before self-admin2.02.23.3-1.1-1.6-1.8-1.3-1.6-1.4-1.8-1.0-1.8-1.1
Distance traveled after self-admin0.70.81.81.40.70.40.80.90.9-0.01.10.81.1
Delta time in closed arm before/after self-admin0.30.31.30.40.40.8-0.10.6-0.11.1-0.50.5-0.2
Delta time in open arm before/after self-admin5.04.87.5-2.7-2.4-1.9-1.6-2.7-1.9-2.4-1.4-2.7-1.6
Diff in mean of infusions in LGA sessions0.20.20.7-0.4-0.4-0.40.0-0.8-0.1-0.60.2-0.7-0.1
Extinction: sum of active levers before priming0.90.92.3-0.9-1.0-0.9-0.9-0.9-0.7-1.5-0.5-0.8-0.9
Active lever presses in extinction session 60.30.31.2-0.6-0.6-0.8-0.3-0.5-0.2-1.10.2-0.5-0.1
Delta distance traveled before/after self-admin2.12.23.31.71.61.31.31.71.50.91.41.81.3
Delta ambulatory time before/after self-admin1.51.72.71.51.31.21.01.61.40.21.41.71.1
Time in closed arm before self-admin5.36.18.0-2.8-2.6-2.8-2.1-2.6-2.2-2.7-1.8-2.7-2.0
Time in closed arm after self-admin0.70.81.6-1.3-0.9-0.7-0.4-1.2-0.6-0.9-0.3-1.3-0.4
Time in open arm before self-admin5.86.211.03.32.62.41.63.22.12.41.53.21.8
Time in open arm after self-admin0.30.40.6-0.5-0.7-0.1-0.6-0.6-0.6-0.8-0.5-0.7-0.6
Sum of active levers in priming session hrs 5-61.01.01.7-0.9-1.1-1.0-0.9-1.1-0.8-1.3-0.5-1.1-0.8
Time to tail flick, vehicle, before self-admin0.20.21.50.10.20.2-0.10.2-0.11.2-0.40.2-0.2
Time to tail flick, vehicle, after self-admin0.30.30.5-0.6-0.4-0.5-0.4-0.5-0.60.4-0.7-0.5-0.6
Time to tail flick, test, before self-admin0.70.71.20.40.90.81.00.81.00.71.00.71.1
Time to tail flick, test, after self-admin0.70.71.51.10.81.00.21.20.41.0-0.01.10.3
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.2-0.1-0.4-0.1-0.0-0.1-0.4-0.00.0-0.1
Delta time to tail flick, test, before/after SA0.20.20.91.00.40.3-0.00.60.10.5-0.10.6-0.0
Ambulatory time before self-admin1.01.12.7-1.1-1.0-1.6-0.8-1.0-0.9-1.2-0.7-1.2-0.6
Ambulatory time after self-admin2.02.33.92.01.41.11.41.61.70.11.91.41.7
Total heroin consumption0.10.10.5-0.2-0.3-0.7-0.3-0.1-0.2-0.2-0.2-0.2-0.2
Area under the delay curve0.10.10.20.10.30.40.50.10.30.20.50.00.5
Delay disc. indifference point, 0s delay2.22.43.51.41.61.91.61.41.61.31.51.41.7
Delay disc. indifference point, 16s delay0.00.00.1-0.00.10.30.3-0.10.20.10.3-0.10.3
Delay disc. indifference point, 2s delay1.71.93.91.11.21.31.71.01.60.22.00.91.8
Delay disc. indifference point, 24s delay0.30.30.50.60.60.20.30.70.40.70.20.60.3
Delay disc. indifference point, 4s delay0.80.91.10.91.00.91.10.81.00.91.00.81.0
Delay disc. indifference point, 8s delay0.30.30.6-0.7-0.6-0.4-0.5-0.6-0.7-0.1-0.7-0.7-0.5
Delay discount exponential model param0.10.10.2-0.1-0.2-0.3-0.5-0.1-0.3-0.1-0.5-0.0-0.5
Delay discount hyperbolic model param0.20.20.5-0.3-0.5-0.5-0.7-0.4-0.5-0.3-0.7-0.2-0.7
Fecal boli incidents, locomotor time 12.22.44.7-1.9-1.6-1.4-0.9-2.2-1.3-1.3-1.0-2.1-1.2
Change in fecal boli incidents, locomotor task0.20.20.40.60.40.40.20.50.40.00.30.60.3
Time >=10cm from walls, locomotor time 10.50.50.9-0.7-0.10.80.9-0.90.30.10.7-1.00.7
Bouts of movement, locomotor time 10.10.10.3-0.4-0.2-0.10.1-0.6-0.0-0.30.2-0.50.1
Total resting periods, locomotor time 10.30.40.80.30.50.70.90.10.70.40.90.20.8
Rest time, locomotor task time 10.20.20.40.60.50.10.40.50.50.30.40.60.3
Distance moved, locomotor task time 10.10.10.4-0.5-0.3-0.1-0.0-0.6-0.2-0.4-0.0-0.6-0.0
Vertical activity count, locomotor time 10.10.10.60.30.30.30.00.40.00.8-0.30.40.0
Time >=10cm from walls, locomotor time 20.70.71.8-1.0-0.7-0.00.3-1.3-0.1-1.30.6-1.30.3
Bouts of movement, locomotor time 21.11.22.40.71.01.21.40.61.30.41.60.61.5
Total resting periods, locomotor time 21.21.32.70.81.01.31.50.61.30.41.60.61.6
Rest time, locomotor task time 20.10.10.40.40.30.2-0.00.40.10.6-0.20.5-0.1
Distance moved, locomotor task time 20.10.20.4-0.5-0.3-0.10.2-0.6-0.0-0.50.3-0.70.3
Vertical activity count, locomotor time 20.30.40.60.50.60.50.70.60.70.40.70.50.8
Weight adjusted by age0.70.81.8-1.0-0.9-1.0-0.5-1.3-0.6-1.1-0.3-1.1-0.6
Seeking ratio, delayed vs. immediate footshock1.61.92.8-1.4-1.5-1.4-1.2-1.5-1.2-1.7-1.0-1.5-1.2
Locomotion in novel chamber1.72.12.41.51.51.41.41.51.51.01.51.51.5
Locomotion in novel chamber post-restriction1.21.42.11.21.31.41.01.21.01.50.81.21.0
Progressive ratio0.60.72.10.80.81.10.40.90.41.5-0.00.90.4
Food seeking constrained by brief footshock0.10.10.2-0.2-0.2-0.4-0.4-0.1-0.30.2-0.4-0.1-0.4
Seeking ratio, punishment vs. effort1.11.32.8-1.1-1.2-1.7-1.0-1.1-0.9-1.3-0.7-1.1-1.0
Run reversals in cocaine runway, females0.20.20.80.00.1-0.0-0.3-0.0-0.30.9-0.70.1-0.5
Run reversals in cocaine runway, males0.60.61.80.40.50.81.10.21.0-0.21.30.21.0
Latency to leave start box in cocaine runway6.36.98.12.82.82.72.52.82.52.72.22.82.3
Latency to leave start box in cocaine runway, F4.85.27.42.52.52.02.02.52.12.71.72.61.9
Latency to leave start box in cocaine runway, M1.51.43.41.01.11.91.31.01.21.01.20.91.1
Cd content in liver0.70.81.9-0.5-0.7-1.0-1.3-0.2-1.0-0.2-1.4-0.2-1.2
Co content in liver0.50.61.11.00.90.30.51.00.61.10.31.00.5
Cu content in liver0.10.10.3-0.3-0.3-0.10.0-0.3-0.0-0.60.2-0.30.0
Fe content in liver1.72.04.0-1.4-1.6-1.2-1.4-1.4-1.3-2.0-1.0-1.4-1.3
K content in liver0.00.00.0-0.00.0-0.10.1-0.00.1-0.10.2-0.00.1
Mg content in liver0.20.20.5-0.4-0.4-0.7-0.3-0.4-0.3-0.7-0.1-0.4-0.2
Mn content in liver1.92.12.41.51.51.51.41.51.51.41.31.51.4
Na content in liver0.60.71.5-1.1-0.9-0.4-0.4-1.1-0.6-1.2-0.2-1.1-0.4
Rb content in liver0.60.81.6-1.1-0.9-0.8-0.2-1.3-0.5-1.2-0.0-1.3-0.2
Se content in liver0.10.20.90.20.00.10.10.20.4-0.90.60.20.3
Sr content in liver0.50.51.00.4-0.1-0.6-1.00.7-0.60.0-1.00.7-0.9
Zn content in liver0.00.00.1-0.1-0.1-0.3-0.20.1-0.20.2-0.30.1-0.2