Hub : Genes

Mrpl42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000042740 0.1 0.04 1.4e-09 0.08 0.09 0.09 0.09 1.5e-09 7.5e-10 4.5e-10 7.7e-10
2 BLA gene expression ENSRNOG00000042740 0.32 0.1 4.7e-10 0.18 0.17 0.2 0.19 4.2e-10 1.2e-09 6.3e-11 1.6e-10
3 BLA isoform ratio ENSRNOT00000066322 0.17 0.07 2.5e-06 0.07 0.1 0.11 0.11 1.8e-04 3.9e-06 1.6e-06 1.6e-06
4 Brain gene expression ENSRNOG00000042740 0.29 0.08 0.0e+00 0.28 0.26 0.28 0.28 2.9e-26 1.4e-23 1.5e-25 2.3e-26
5 Brain isoform ratio ENSRNOT00000066322 0.03 0.02 5.1e-03 0.03 0.01 0.01 0.01 7.3e-04 2.1e-02 3.1e-02 1.7e-02
6 LHb gene expression ENSRNOG00000042740 0.22 0.11 3.0e-03 0.08 0.05 0.04 0.06 7.1e-03 2.7e-02 4.3e-02 1.3e-02
7 Liver gene expression ENSRNOG00000042740 0.22 0.1 2.0e-08 0.06 0.07 0.08 0.07 2.3e-07 1.8e-08 8.8e-09 2.1e-08
8 Liver intron excision ratio chr7:30140191:30141604 0.03 0.02 9.0e-03 0.01 0.01 0.02 0.01 6.9e-03 1.1e-02 2.2e-03 1.2e-02
9 NAcc gene expression ENSRNOG00000042740 0.19 0.09 3.8e-08 0.12 0.11 0.11 0.11 3.4e-09 2.2e-08 2.3e-08 1.7e-08
10 NAcc isoform ratio ENSRNOT00000066322 0.08 0.04 2.2e-03 0.01 0.03 0.03 0.03 4.6e-02 2.1e-03 2.2e-03 5.5e-03
11 NAcc intron excision ratio chr7:30118152:30127861 0.05 0.03 7.5e-03 0.01 0.03 0.01 0.01 4.1e-02 3.7e-03 1.0e-01 3.2e-02
12 OFC gene expression ENSRNOG00000042740 0.28 0.12 9.9e-04 0.06 0.08 0.11 0.1 1.5e-02 5.4e-03 1.6e-03 2.6e-03
13 PL gene expression ENSRNOG00000042740 0.19 0.07 1.8e-10 0.17 0.14 0.15 0.17 6.1e-13 1.9e-10 1.9e-11 6.0e-13
14 PL isoform ratio ENSRNOT00000066322 0.1 0.04 5.4e-07 0.09 0.1 0.1 0.1 3.3e-07 7.8e-08 7.3e-08 1.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.93.114.4-0.00.8-2.30.4-1.61.8-0.1-1.51.0-3.8-2.91.61.7-0.1
BMI without tail0.71.47.8-1.1-0.1-0.9-0.0-1.01.50.30.70.1-2.8-2.20.3-0.4-0.4
Body weight1.14.724.7-1.80.6-1.20.4-1.31.80.43.90.7-5.0-3.70.90.30.2
Epididymis fat weight0.20.63.0-0.9-0.3-0.5-0.3-0.10.8-1.00.2-0.3-1.7-1.2-0.2-0.30.5
Glucose0.00.00.20.0-0.1-0.4-0.1-0.20.10.2-0.40.00.3-0.1-0.1-0.1-0.1
Heart weight0.40.62.4-0.6-0.80.0-0.30.8-0.90.9-0.3-0.8-0.20.1-0.9-1.01.6
Left kidney weight0.20.43.2-0.70.00.1-0.00.00.20.71.80.1-1.0-0.90.10.20.4
Right kidney weight0.30.83.2-0.40.6-0.00.6-0.50.81.21.80.7-1.8-1.10.70.6-0.0
Tail length1.13.329.6-1.9-0.21.10.4-0.00.61.35.4-0.2-1.5-1.1-0.8-2.3-0.4
Length with tail1.24.444.4-2.20.00.90.3-0.00.41.16.7-0.1-2.2-1.6-0.6-1.60.3
Length without tail0.40.99.5-0.80.30.00.30.00.00.23.10.1-1.3-1.00.10.10.5
Liver weight, left1.22.04.81.11.3-1.71.6-1.41.80.7-1.41.2-2.2-1.81.0-0.4-0.8
Liver weight, right1.21.94.81.11.5-0.91.9-1.01.62.20.21.6-1.8-1.31.40.0-1.1
Parametrial fat weight0.30.61.6-0.5-0.90.3-0.71.0-1.00.2-1.0-0.90.50.7-0.9-0.61.2
Retroperitoneal fat weight0.72.47.60.71.3-1.91.5-1.51.71.60.01.4-2.8-2.30.9-0.8-0.7
Intraocular pressure0.30.41.50.20.2-0.50.1-0.90.9-1.2-1.00.2-0.6-0.50.3-0.3-0.9
Extensor digitorum longus weight0.10.31.1-0.10.3-0.30.2-0.50.30.60.60.4-1.0-0.50.40.80.1
Soleus weight0.20.72.6-0.6-0.70.6-0.81.2-1.1-0.90.4-0.80.00.5-0.40.81.6
Tibialis anterior weight0.41.32.9-1.3-1.50.5-1.71.1-1.0-1.2-0.1-1.50.10.6-1.4-0.21.6
Tibia length0.72.07.2-1.5-0.4-1.0-0.3-0.60.60.01.9-0.3-2.7-2.4-0.8-2.40.6
Number of licking bursts0.30.31.4-0.2-0.2-0.8-0.1-0.00.2-0.8-1.2-0.1-0.6-0.8-0.1-0.20.5
Food consumed during 24 hour testing period0.60.72.6-1.4-1.10.8-1.10.6-0.5-0.41.6-1.00.60.5-0.50.30.3
Times rat made contact with spout0.60.72.6-0.7-1.0-0.4-0.60.6-0.5-1.6-0.4-1.20.5-0.7-1.0-1.00.6
Mean time between licks in bursts0.91.22.41.01.1-0.91.0-0.61.11.0-1.20.7-1.6-1.31.41.3-0.5
Mean num. licks in bursts0.10.20.8-0.0-0.30.3-0.10.3-0.5-0.20.5-0.50.90.4-0.4-0.3-0.0
Std. dev. time between licks in bursts0.70.81.91.20.9-0.60.7-0.10.51.1-1.40.7-1.0-0.41.11.30.2
Water consumed over 24 hours1.31.53.8-1.9-1.61.0-1.41.0-1.2-0.81.7-1.50.80.6-1.10.31.2
Indifference point 0 sec1.32.13.0-1.3-1.61.5-1.51.4-1.7-1.71.6-1.51.41.3-1.7-1.00.9
Indifference point AUC0.20.22.7-0.00.10.00.3-0.1-0.0-0.10.40.20.2-0.1-0.6-1.6-0.1
Indifference point function ln k0.30.41.5-0.9-0.80.4-0.70.6-0.5-0.30.1-0.90.00.4-0.01.20.8
Indifference point function log k0.30.41.5-0.9-0.80.4-0.70.6-0.5-0.30.1-0.90.00.4-0.01.20.8
Delay discounting total patch changes 0 sec1.11.82.6-1.2-1.41.4-1.31.4-1.6-1.41.6-1.41.41.3-1.4-0.50.9
Delay discounting total patch changes 12 sec0.30.42.50.40.1-0.40.20.00.1-1.3-0.40.10.1-0.7-0.5-1.6-0.6
Delay discounting total patch changes 18 sec0.91.33.6-1.0-1.00.7-1.10.7-0.8-1.91.4-1.01.10.5-1.5-1.50.3
Delay discounting total patch changes 24 sec0.60.72.0-0.9-0.80.8-1.00.4-0.7-1.21.4-0.90.70.3-1.0-0.90.2
Delay discounting total patch changes 6 sec0.50.72.2-0.7-1.00.9-1.10.9-0.8-1.50.7-0.80.80.6-0.9-0.30.2
Delay discounting time to switch 0 sec0.10.20.50.60.7-0.20.4-0.30.0-0.5-0.40.6-0.2-0.10.50.3-0.4
Delay discounting water rate 0 sec0.40.72.8-0.3-0.2-1.30.3-0.50.7-0.2-0.6-0.0-1.6-1.7-0.2-1.00.2
Delay discounting water rate 12 sec0.20.41.4-0.7-0.4-0.3-0.0-0.20.8-1.20.5-0.4-0.8-1.0-0.0-0.1-0.2
Delay discounting water rate 18 sec1.01.33.20.50.7-1.21.0-1.11.81.4-0.90.6-1.7-1.51.10.3-1.1
Delay discounting water rate 24 sec0.60.83.5-0.4-0.0-1.20.3-0.81.20.20.0-0.0-1.9-1.80.0-0.9-0.2
Delay discounting water rate 6 sec2.94.213.20.71.7-2.41.9-2.52.60.4-0.51.6-3.6-3.41.70.1-1.3
Locomotor activity0.71.24.60.40.8-1.51.0-0.90.70.9-0.50.7-2.1-2.10.4-0.60.1
Locomotor testing distance0.81.34.40.60.6-2.00.7-0.90.7-0.0-1.80.4-2.0-2.10.3-0.50.0
Locomotor testing rearing0.81.33.40.80.8-1.80.7-1.41.0-0.2-1.30.7-1.5-1.80.4-1.1-0.7
Light reinforcement 10.20.30.70.50.7-0.80.4-0.70.30.4-0.30.7-0.5-0.60.70.3-0.5
Light reinforcement 20.40.51.4-1.0-0.60.8-0.60.6-0.7-1.20.8-0.50.10.8-0.30.60.8
Reaction time number correct0.20.21.1-0.0-0.3-0.60.20.10.2-0.3-0.8-0.3-0.1-0.6-0.3-1.1-0.2
Reaction time mean minus median0.50.74.10.0-0.31.3-0.20.8-0.62.00.7-0.30.91.1-0.10.70.2
Reaction time mean minus median AUC0.40.63.90.40.00.90.10.6-0.32.00.4-0.10.80.80.40.90.0
Reaction time num false alarms0.81.12.9-0.6-0.81.4-1.01.1-1.40.80.8-0.81.71.6-0.70.10.5
Reaction time num false alarms AUC0.40.61.9-0.2-0.51.0-0.60.7-0.91.40.3-0.51.31.3-0.40.10.3
Reaction time trials correct on left0.20.21.1-0.0-0.3-0.60.20.10.2-0.3-0.8-0.3-0.1-0.6-0.3-1.1-0.2
Reaction time trials on left0.10.21.0-0.0-0.4-0.50.10.10.2-0.3-0.9-0.3-0.0-0.5-0.4-1.0-0.1
Reaction time mean0.20.31.30.20.3-0.70.2-0.40.51.1-0.60.4-1.0-0.70.30.30.2
Reaction time mean AUC0.20.31.40.20.3-0.50.1-0.40.51.2-0.20.4-1.0-0.60.40.40.1
Median of all reaction times0.40.62.50.20.5-1.20.2-0.80.80.5-0.70.6-1.6-1.20.50.40.1
Reaction time omissions1.31.87.7-0.4-0.91.5-1.31.6-1.30.5-0.6-1.11.41.80.12.81.4
Reaction time false alarm rate0.40.61.9-0.2-0.21.2-0.60.5-0.91.30.6-0.31.11.4-0.20.50.3
Reaction time premature initiation rate2.93.95.42.12.1-2.32.2-2.12.31.2-2.32.1-2.3-2.11.80.0-1.6
Reaction time premature initiations2.53.65.21.91.8-2.32.2-1.92.31.1-2.31.8-2.1-2.21.5-0.4-1.8
Std. dev. reaction times0.40.64.70.4-0.00.8-0.00.5-0.52.20.2-0.00.60.90.10.80.4
Reaction time trials completed0.10.21.0-0.0-0.4-0.50.10.10.2-0.3-0.9-0.3-0.0-0.5-0.4-1.0-0.1
Reaction time trials AUC0.20.31.10.2-0.1-0.80.3-0.20.4-0.3-1.0-0.1-0.3-0.8-0.2-1.1-0.3
Social response proportion0.60.62.60.30.7-0.61.0-0.60.40.9-0.30.6-1.6-1.20.60.30.3
Social responses3.24.27.12.12.1-2.22.6-2.02.01.6-2.02.1-2.5-2.71.90.3-1.6
Social time0.40.51.30.60.6-0.90.6-0.70.6-0.9-0.80.5-0.7-1.20.4-0.2-0.4
Conditioned locomotion0.60.71.3-0.8-0.90.9-0.51.1-1.1-0.00.9-0.80.91.0-0.70.00.9
Cocaine response after cond. corrected0.30.31.9-0.8-0.40.5-0.60.4-0.3-1.40.4-0.7-0.1-0.0-0.10.60.4
Cocaine response after cond. not corrected0.20.21.2-0.7-0.40.2-0.40.3-0.2-1.10.1-0.5-0.2-0.2-0.10.60.4
Cocaine response before conditioning0.40.50.90.90.7-0.90.8-0.70.50.9-1.00.9-0.3-0.60.60.6-0.5
Saline control response0.10.10.50.10.20.00.4-0.20.3-0.10.70.1-0.1-0.30.20.0-0.3
Condit. Reinf. active minus inactive responses0.81.04.11.51.0-0.60.9-0.60.72.0-1.21.0-0.3-0.20.90.4-0.7
Condit. Reinf. active-inactive response ratio0.10.10.30.4-0.10.2-0.3-0.10.20.5-0.10.10.40.3-0.1-0.2-0.5
Condit. Reinf. active responses0.91.23.71.61.2-0.71.0-0.50.61.9-1.31.3-0.6-0.31.31.1-0.4
Condit. Reinf. inactive responses0.91.14.31.21.2-0.50.9-0.20.11.4-1.11.3-0.5-0.11.62.10.1
Condit. Reinf. lever presses2.53.49.52.22.2-1.31.6-2.01.83.1-0.52.3-1.3-0.92.11.6-1.6
Condit. Reinf. lever reinforcers received0.71.03.81.41.0-0.60.7-0.40.31.9-1.21.1-0.5-0.11.11.2-0.0
Pavlov. Cond. lever latency0.30.31.2-0.9-0.60.4-0.20.3-0.1-1.10.4-0.70.3-0.2-0.6-0.9-0.3
Pavlov. Cond. magazine entry latency0.20.31.60.50.4-0.60.1-0.60.30.0-0.30.5-0.2-0.40.61.3-0.2
Pavlov. Cond. change in total contacts0.30.42.90.30.4-0.80.1-0.60.50.4-0.20.4-1.7-0.90.2-0.20.5
Pavlov. Cond. index score0.20.31.10.50.4-0.70.2-0.50.30.4-0.30.6-0.7-0.40.61.00.2
Pavlov. Cond. latency score0.30.40.70.70.6-0.70.4-0.70.50.7-0.30.7-0.8-0.50.60.8-0.0
Pavlov. Cond. lever contacts0.40.51.11.00.7-1.00.4-0.50.30.7-1.00.8-1.0-0.40.70.70.4
Pavlov. Cond. magazine entry number0.60.82.2-0.6-0.61.5-0.51.1-0.8-0.31.1-0.71.21.1-0.7-0.90.1
Pavlov. Cond. intertrial magazine entries0.30.42.90.40.60.00.5-0.20.21.7-0.10.5-0.1-0.10.80.6-0.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.70.50.4-0.60.1-0.50.20.2-0.10.5-0.6-0.40.40.80.2
Pavlov. Cond. response bias0.30.51.10.80.5-1.10.2-0.50.20.2-1.00.7-1.0-0.60.60.80.5
Conditioned reinforcement - actives1.61.52.91.41.6-1.41.7-1.51.10.50.01.6-1.2-1.51.1-0.4-1.1
Conditioned reinforcement - inactives0.91.12.71.01.2-1.11.6-1.20.61.00.50.9-0.6-1.10.3-1.7-0.7
Conditioned locomotion0.20.31.3-0.10.4-0.50.7-0.40.10.40.80.4-0.5-0.6-0.1-1.2-0.0
Intermittent access intake day 1-15 change3.03.04.71.62.0-1.91.8-2.02.00.3-0.82.0-1.8-2.22.01.1-1.7
Intermittent access intake escalation2.62.64.41.61.8-1.91.6-1.81.80.0-1.01.8-1.5-2.11.91.0-1.6
Intermittent access intake escalation 21.01.01.90.91.1-1.31.1-1.11.2-0.2-0.51.2-1.1-1.40.90.1-0.9
Intermitt. access day 1 inactive lever presses1.21.33.7-0.4-1.11.3-1.01.1-1.21.20.4-1.21.91.7-1.2-0.80.6
Intermitt. access day 15 inactive lever presses0.40.41.70.2-0.30.6-0.20.2-0.71.30.6-0.41.11.0-0.4-0.3-0.1
Intermitt. access escalation Index0.40.41.80.70.4-0.20.3-0.40.71.3-0.90.6-0.1-0.00.60.5-0.8
Intermittent access day 1 total infusions0.60.63.4-0.30.40.20.1-0.40.4-0.61.80.5-0.9-0.50.81.5-0.1
Intermittent access day 15 total infusions1.71.93.50.61.6-1.01.3-1.61.5-0.41.11.7-1.9-1.81.81.4-1.2
Intermittent access terminal intake (last 3 days)1.51.73.70.51.4-0.91.0-1.41.2-0.21.21.5-1.9-1.61.71.6-0.8
Intermittent access total infusions0.80.92.3-0.10.7-0.40.4-0.70.6-0.81.50.8-1.5-1.21.01.5-0.2
Intermittent access day 1 locomotion1.21.26.8-1.5-0.81.3-0.80.8-1.0-0.92.6-0.80.30.7-0.9-0.11.0
Intermittent access day 15 total locomotion1.21.39.1-1.3-0.71.2-0.50.7-0.9-0.63.0-0.71.00.6-1.0-0.90.3
Intermittent access total locomotion0.91.18.6-1.4-0.51.1-0.60.5-0.6-0.82.9-0.5-0.10.3-0.60.10.5
Intermittent access standard deviation1.11.23.40.51.1-1.41.2-1.11.1-1.30.01.0-1.5-1.80.8-0.1-0.8
Cocaine induced anxiety2.22.64.7-1.3-1.71.2-1.81.8-2.2-1.30.1-1.62.02.1-1.6-0.11.8
Post-drug Anxiety1.61.74.5-0.7-1.31.3-1.51.4-1.5-1.20.0-1.22.12.0-1.00.60.9
Baseline Anxiety0.10.10.80.20.10.50.0-0.10.5-0.10.50.10.2-0.10.40.5-0.9
Lifetime Intake0.80.92.5-0.10.7-0.40.3-0.70.4-1.11.30.7-1.5-1.11.11.60.0
Incentive Sensitization - Responses1.81.83.41.31.7-1.01.7-1.61.40.8-0.21.6-1.3-1.81.3-0.1-1.5
Incentive Sensitization - Breakpoint1.61.62.91.31.6-1.01.7-1.61.30.8-0.11.5-1.1-1.71.2-0.1-1.4
Progressive ratio test 1 active lever presses0.80.85.2-0.50.50.00.3-0.60.3-1.02.30.6-1.3-1.00.60.8-0.1
Progressive ratio test 1 breakpoint0.90.93.8-0.20.7-0.20.5-0.80.6-0.81.90.8-1.6-1.30.80.9-0.2
Progressive ratio test 1 inactive lever presses0.30.41.70.40.60.10.5-0.50.21.11.30.50.00.00.60.5-0.6
Progressive ratio test 2 active lever presses1.92.03.61.11.7-1.11.7-1.81.40.30.41.8-1.8-1.91.60.5-1.4
Progressive ratio test 2 breakpoint2.32.54.81.31.9-1.31.8-2.01.6-0.00.12.0-1.9-2.21.70.7-1.5
Progressive ratio test 2 inactive lever presses0.20.30.70.50.6-0.10.8-0.70.20.20.80.6-0.0-0.30.2-0.6-0.5
Total sessions with >9 infusions0.70.72.4-0.30.7-0.30.4-0.80.3-1.40.80.7-1.6-0.80.91.30.1
Short access day 1 total inactive lever presses0.20.20.9-0.3-0.30.1-0.30.3-0.9-0.30.3-0.40.60.5-0.5-0.00.9
Short access day 10 total inactive lever presses0.70.83.31.00.00.4-0.2-0.00.11.8-0.9-0.21.71.20.40.9-0.9
Short access day 1 total infusions1.71.83.80.91.6-1.31.3-1.60.8-0.5-0.21.7-2.0-1.51.71.8-0.4
Short access day 10 total infusions0.50.63.1-1.0-0.20.2-0.40.2-0.1-1.11.7-0.3-1.1-0.60.00.80.7
Short access total infusions0.91.03.00.30.9-0.80.6-1.00.5-1.50.40.9-1.7-1.41.11.50.0
Short access day 1 locomotion0.50.61.10.50.9-0.60.7-0.90.5-0.50.40.9-0.8-0.80.91.0-0.6
Short access day 10 total locomotion0.40.41.2-0.8-0.50.5-0.30.5-0.30.61.0-0.8-0.00.3-0.9-1.10.4
Short access total locomotion0.30.31.9-0.4-0.10.30.00.1-0.4-0.91.4-0.3-0.1-0.2-0.5-0.60.2
Compulsive drug intake1.91.95.1-0.5-1.51.4-1.21.4-1.4-0.1-0.3-1.82.21.8-1.7-1.50.6
One hour access (0.3 mA shock)1.11.33.10.71.3-1.21.4-1.41.1-0.30.81.0-1.5-1.71.0-0.2-0.9
One hour access (shock baseline)2.12.44.80.81.8-1.61.7-1.81.6-0.11.21.7-2.1-2.21.80.8-1.2
Number of responses in last shaping day0.20.21.00.00.2-0.40.4-0.30.1-1.00.00.2-0.4-0.6-0.1-0.7-0.1
Context. condit. distance diff. score0.70.81.9-1.3-0.91.0-1.00.6-0.6-1.41.4-0.90.10.6-0.8-0.30.6
Locomotion velocity, session 10.70.72.91.60.8-0.70.9-0.40.40.6-1.70.90.6-0.20.70.1-0.8
Locomotion distance, session 10.60.72.21.51.2-0.80.9-0.20.20.5-1.01.3-0.4-0.41.10.80.1
Locomotion velocity, session 20.40.51.7-0.1-0.01.30.10.4-0.60.61.30.21.01.1-0.2-0.1-0.2
Locomotion distance, session 20.71.01.91.31.2-1.21.0-0.70.41.4-0.71.4-1.2-0.90.90.00.3
Locomotion velocity, session 30.60.61.5-0.3-0.51.2-0.30.6-0.40.71.2-0.51.01.0-1.0-1.2-0.2
Locomotion distance, session 30.10.10.5-0.4-0.20.1-0.50.3-0.2-0.20.5-0.3-0.40.1-0.30.20.7
Stereotopy head waving bouts, day 30.91.12.71.31.2-0.31.6-1.01.00.9-0.11.2-0.2-0.30.4-1.7-1.6
Stereotopy head waving duration, day 30.50.62.30.70.50.11.0-0.60.60.80.20.50.40.00.0-1.5-1.4
Locomotion velocity, session 70.20.21.20.30.2-0.30.50.10.21.1-0.50.1-0.4-0.3-0.1-0.70.0
Locomotion distance, session 70.30.31.4-0.1-0.30.2-0.20.9-1.00.50.0-0.30.50.7-0.50.11.2
Stereotopy head waving bouts, day 70.30.41.50.2-0.30.6-0.00.2-0.1-0.10.6-0.31.10.5-0.7-1.2-0.6
Stereotopy head waving duration, day 70.20.31.0-0.1-0.60.4-0.40.3-0.2-0.40.3-0.51.00.5-0.7-0.9-0.3
Locomotion velocity, session 80.30.42.3-0.00.30.5-0.1-0.40.20.81.50.50.20.40.40.5-0.7
Locomotion distance, session 80.40.53.00.00.6-0.80.6-0.60.30.30.60.7-1.7-1.00.2-0.60.5
Degree of sensitization distance0.20.20.80.40.4-0.00.50.2-0.30.9-0.30.40.20.20.40.40.2
Degree of sensitization stereotypy1.01.12.9-0.6-1.11.2-1.11.0-1.0-0.80.9-1.11.71.4-1.1-0.30.4
Condit. Reinf. active minus inactive responses1.21.39.21.40.6-1.41.1-0.70.80.8-3.00.5-0.0-0.80.6-0.2-0.9
Condit. Reinf. active-inactive response ratio0.80.97.90.80.1-1.30.5-0.40.70.1-2.8-0.1-0.2-0.8-0.0-0.7-0.5
Condit. Reinf. active responses1.31.610.61.60.7-1.51.0-0.90.90.8-3.30.60.3-0.70.6-0.5-1.3
Condit. Reinf. inactive responses0.30.41.20.90.5-0.30.3-0.50.20.8-1.10.60.60.20.60.4-0.8
Incentive salience index mean2.32.712.82.01.1-2.31.7-1.31.30.9-3.61.0-0.5-1.60.7-1.0-1.4
Condit. Reinf. lever presses1.52.05.91.81.2-2.11.6-1.41.10.7-2.41.2-0.6-1.50.6-1.1-1.2
Time in familiar zone, hab. session 10.10.10.50.10.00.1-0.2-0.1-0.00.7-0.30.00.00.20.10.50.0
Time in novel zone, hab. session 12.32.34.1-1.6-1.61.3-1.61.9-1.9-1.90.5-1.51.21.4-1.20.22.0
Total zone transitions, hab. session 13.34.68.22.82.4-2.92.7-1.81.71.4-2.42.5-2.2-2.61.7-0.6-1.0
Total locomotion distance, hab. session 16.08.514.63.73.5-3.33.8-2.52.62.2-2.93.5-2.6-3.22.90.2-2.1
Locomotion velocity, hab. session 19.914.223.04.64.3-4.34.8-3.53.83.0-3.54.2-3.5-4.33.5-0.3-3.1
Time in familiar zone, hab. session 20.80.86.10.90.8-0.20.7-0.30.21.00.30.8-0.3-0.11.32.5-0.2
Time in novel zone, hab. session 20.60.62.9-0.8-0.90.4-0.80.5-0.5-0.2-0.4-0.90.30.4-1.1-1.70.7
Total zone transitions, hab. session 20.91.13.31.61.0-1.71.0-0.30.21.1-1.81.1-0.8-1.00.6-0.30.6
Total locomotion distance, hab. session 25.67.411.73.43.0-3.43.1-2.32.42.3-3.43.0-2.7-3.02.60.2-1.5
Locomotion velocity, hab. session 26.28.413.53.53.1-3.73.3-2.62.72.4-3.53.1-2.9-3.22.7-0.1-1.8
Novel to familiar place preference ratio0.50.51.40.20.20.9-0.20.0-0.10.91.20.31.10.80.51.1-0.8
Novelty place preference0.60.61.80.20.10.9-0.30.1-0.21.11.00.11.30.90.41.1-0.8
Time in novel zone, NPP test0.60.72.0-0.1-0.21.0-0.60.4-0.50.91.1-0.21.41.10.21.3-0.4
Total zone transitions, NPP test0.71.02.11.11.0-1.41.1-0.40.41.5-1.01.0-1.5-1.20.4-0.80.5
Total locomotion distance, NPP test6.38.814.63.63.6-3.03.8-2.62.72.7-2.43.5-3.2-3.13.10.8-2.0
Locomotion velocity, NPP test6.08.614.43.53.5-3.03.8-2.72.82.7-2.43.5-3.0-3.03.00.4-2.2
Pavlov. Cond. lever latency0.50.61.8-1.0-0.20.9-0.50.6-0.20.21.3-0.4-1.10.00.21.21.0
Pavlov. Cond. magazine entry latency0.20.32.20.70.1-0.7-0.10.1-0.4-0.5-1.50.20.60.10.00.10.4
Pavlov. Cond. change in total contacts0.40.52.60.70.2-1.00.0-0.3-0.0-1.6-1.50.30.3-0.20.20.0-0.1
Pavlov. Cond. index score0.60.84.21.30.5-1.40.6-0.60.3-0.3-2.10.70.6-0.40.2-0.6-0.6
Pavlov. Cond. latency score0.70.83.61.40.6-1.40.7-0.70.4-0.3-1.90.70.7-0.30.2-0.9-0.8
Pavlov. Cond. lever contacts0.91.02.61.40.8-1.41.0-1.10.7-0.4-1.60.90.5-0.60.3-1.0-1.3
Pavlov. Cond. magazine entry number0.30.32.0-0.50.10.60.1-0.30.60.71.40.0-0.8-0.20.1-0.0-0.5
Pavlov. Cond. intertrial magazine entries1.51.83.9-1.8-1.80.6-1.71.4-1.4-1.3-0.2-1.8-0.10.5-1.4-0.22.0
Pavlov. Cond. lever-magazine prob. diff.0.60.73.91.30.5-1.40.6-0.60.2-0.3-2.00.70.4-0.40.2-0.5-0.4
Pavlov. Cond. response bias0.50.64.11.00.2-1.20.4-0.40.1-0.7-2.00.40.6-0.4-0.0-0.8-0.4
Bone: apparent density0.91.43.7-1.0-1.60.7-0.61.0-1.1-1.30.2-1.41.30.7-1.9-1.90.8
Bone surface0.10.10.5-0.1-0.1-0.40.6-0.1-0.1-0.2-0.30.1-0.7-0.6-0.3-0.50.5
Bone volume0.20.31.4-0.5-0.7-0.1-0.10.2-0.4-0.5-0.2-0.5-0.0-0.2-1.0-1.20.6
Bone: connectivity density0.10.21.20.30.10.31.1-0.0-0.0-0.20.10.30.70.2-0.1-0.3-0.5
Bone: cortical apparent density0.30.40.8-0.4-0.50.6-0.60.9-0.8-0.10.7-0.40.40.5-0.6-0.70.9
Bone: cortical area0.71.12.5-1.1-1.3-0.1-0.90.8-0.9-1.50.2-1.1-0.1-0.2-1.5-1.51.6
Bone: cortical porosity0.30.32.1-0.3-0.21.0-0.10.3-0.20.81.5-0.20.30.6-0.20.1-0.3
Bone: cortical porosity0.10.10.9-0.2-0.10.40.10.00.11.00.8-0.1-0.2-0.0-0.2-0.5-0.2
Bone: cortical thickness0.91.62.6-1.1-1.50.7-1.11.4-1.4-1.51.0-1.31.10.7-1.6-1.11.5
Bone: cortical thickness0.50.61.3-0.6-1.10.6-0.90.9-0.8-0.4-0.0-0.91.10.9-1.0-0.50.7
Bone: cortical tissue density0.30.40.8-0.5-0.50.6-0.60.9-0.80.00.7-0.40.50.6-0.6-0.60.8
Bone: elastic displacement0.50.61.21.00.50.00.3-0.40.41.0-1.00.60.70.70.81.1-1.0
Bone: elastic work1.31.74.2-0.8-1.41.8-1.51.5-1.4-0.30.4-1.32.02.0-1.20.10.7
Bone: endosteal estimation0.30.73.2-1.0-0.5-0.3-0.4-0.1-0.1-0.7-0.7-0.5-1.8-0.6-0.7-0.91.4
Bone: endosteal perimeter0.61.25.6-1.1-0.5-1.2-0.4-0.50.3-1.2-0.8-0.5-2.4-1.7-0.6-1.11.3
Bone: final force3.55.710.7-2.7-3.11.1-2.62.4-2.5-2.40.6-2.91.01.2-3.3-2.13.2
Bone: final moment3.05.09.8-2.3-2.91.0-2.32.4-2.4-2.30.4-2.71.11.1-3.1-2.13.0
Bone: marrow area0.30.73.0-1.0-0.5-0.2-0.5-0.1-0.1-0.7-0.6-0.5-1.7-0.6-0.7-0.91.4
Bone: maximum diameter0.50.92.7-1.2-1.0-0.8-0.70.2-0.4-1.1-0.3-0.8-1.3-1.0-0.9-0.81.6
Bone: maximum force1.32.35.8-1.6-1.90.9-1.71.6-1.7-1.20.5-1.60.40.9-2.0-1.22.4
Bone: maximum moment1.22.04.9-1.3-1.80.8-1.51.6-1.7-1.10.2-1.50.60.9-2.0-1.32.2
Bone: minimum diameter1.12.06.2-1.7-1.6-0.4-1.50.9-1.1-1.90.1-1.5-1.0-0.7-1.7-1.32.5
Bone: periosteal estimation0.61.34.2-1.5-1.2-0.0-1.00.6-0.8-1.2-0.1-1.1-1.2-0.4-1.4-1.32.1
Bone: periosteal perimeter0.50.92.2-1.1-0.9-0.7-0.60.2-0.4-1.0-0.5-0.8-1.3-0.9-1.1-1.31.5
Bone: post-yield work1.11.62.9-1.3-1.40.9-1.41.4-1.5-1.10.9-1.31.11.2-1.4-0.51.7
Bone: stiffness2.03.210.0-2.0-2.10.8-1.52.1-2.1-1.10.9-1.9-0.10.6-2.4-1.73.2
Bone: tissue strength0.50.51.4-0.5-0.70.2-0.40.8-0.9-0.40.4-0.80.20.3-1.0-0.91.2
Bone: trabecular number0.40.73.8-0.4-0.80.3-0.00.2-0.4-1.3-0.2-0.61.00.4-1.3-2.0-0.1
Bone: trabecular spacing0.81.14.31.21.2-0.10.4-0.90.90.7-0.21.0-0.3-0.21.62.1-1.3
Bone: trabecular thickness0.91.12.1-1.2-1.40.6-1.00.9-1.1-0.50.7-1.21.20.7-1.5-1.20.9
Bone: trabecular tissue density0.20.21.3-0.1-0.20.1-0.40.3-0.4-0.30.6-0.20.20.4-0.6-1.20.4
Breakpoint value in progressive ratio session1.31.53.71.51.3-1.41.2-1.20.61.9-1.71.3-0.5-0.51.20.8-0.7
Distance traveled before self-admin2.02.13.01.71.7-1.61.7-1.61.50.7-1.31.7-1.3-1.51.50.4-1.4
Distance traveled after self-admin0.30.41.4-0.3-0.50.0-0.20.5-0.80.3-0.1-0.5-0.3-0.0-0.9-1.11.2
Delta time in closed arm before/after self-admin0.70.71.80.50.5-0.70.4-0.51.00.3-1.30.5-1.4-1.10.91.0-0.2
Delta time in open arm before/after self-admin0.40.31.8-0.1-0.30.3-0.30.3-0.20.20.3-0.31.00.9-0.7-1.3-0.2
Diff in mean of infusions in LGA sessions0.40.52.30.80.2-0.4-0.1-0.1-0.01.5-1.20.10.70.40.41.0-0.3
Extinction: sum of active levers before priming0.40.40.7-0.4-0.80.6-0.80.8-0.6-0.4-0.1-0.80.80.8-0.60.20.7
Active lever presses in extinction session 61.91.93.41.51.5-1.81.4-1.51.20.6-1.81.5-1.7-1.51.0-0.6-0.5
Delta distance traveled before/after self-admin0.80.91.9-0.8-0.90.6-0.71.0-1.20.20.5-0.90.30.6-1.3-1.31.4
Delta ambulatory time before/after self-admin2.42.64.9-1.6-1.81.2-1.71.9-2.1-0.50.8-1.81.21.5-2.1-1.32.2
Time in closed arm before self-admin0.10.11.00.00.2-0.30.2-0.2-0.11.00.50.30.1-0.10.1-0.0-0.1
Time in closed arm after self-admin0.60.61.50.30.6-0.80.5-0.60.8-0.6-1.20.6-1.2-1.01.01.2-0.2
Time in open arm before self-admin0.10.10.2-0.1-0.30.2-0.20.40.10.3-0.4-0.4-0.0-0.0-0.2-0.00.3
Time in open arm after self-admin0.50.51.9-0.1-0.70.5-0.50.7-0.40.70.1-0.71.10.8-1.0-1.40.0
Sum of active levers in priming session hrs 5-62.01.94.32.01.6-2.11.4-1.60.70.4-1.81.6-0.8-1.41.40.8-0.7
Time to tail flick, vehicle, before self-admin0.90.95.2-0.9-0.80.2-0.80.9-1.0-2.30.3-0.81.0-0.0-0.8-0.21.0
Time to tail flick, vehicle, after self-admin0.10.11.30.2-0.3-0.2-0.10.3-0.10.1-1.1-0.20.30.1-0.2-0.10.1
Time to tail flick, test, before self-admin0.90.81.5-1.2-0.90.8-0.81.0-1.0-0.60.7-0.90.30.5-1.2-1.11.2
Time to tail flick, test, after self-admin0.30.30.80.40.5-0.60.6-0.40.5-0.7-0.90.3-0.5-0.70.2-0.5-0.3
Delta time to tail flick, vehicle, before/after SA0.50.51.81.00.4-0.30.3-0.40.71.3-1.00.4-0.40.10.70.6-0.7
Delta time to tail flick, test, before/after SA0.30.30.80.80.5-0.50.5-0.50.8-0.2-0.60.4-0.2-0.40.4-0.3-0.9
Ambulatory time before self-admin1.81.92.91.41.7-1.21.6-1.61.70.6-0.61.7-1.2-1.31.60.5-1.7
Ambulatory time after self-admin0.10.20.6-0.1-0.1-0.30.10.2-0.30.50.2-0.1-0.4-0.2-0.4-0.80.7
Total heroin consumption0.91.04.61.20.9-1.40.8-0.90.41.0-2.10.9-0.6-0.60.90.7-0.0
Area under the delay curve1.41.53.9-1.0-1.30.5-1.01.4-1.6-2.0-0.5-1.20.30.5-1.5-1.01.7
Delay disc. indifference point, 0s delay0.20.20.60.80.5-0.60.7-0.40.00.7-0.50.5-0.2-0.30.2-0.5-0.3
Delay disc. indifference point, 16s delay1.92.04.8-1.5-1.60.6-1.31.8-1.8-1.9-0.4-1.60.10.6-1.5-0.42.2
Delay disc. indifference point, 2s delay0.20.30.50.50.6-0.70.6-0.50.1-0.7-0.70.6-0.6-0.60.4-0.00.0
Delay disc. indifference point, 24s delay2.01.92.7-1.5-1.61.6-1.41.6-1.6-1.21.1-1.60.71.0-1.6-0.81.6
Delay disc. indifference point, 4s delay0.20.20.9-0.5-0.50.1-0.50.6-0.6-0.9-0.2-0.40.30.2-0.30.50.7
Delay disc. indifference point, 8s delay2.22.26.1-1.5-1.51.2-1.51.6-1.9-2.50.3-1.50.81.3-1.6-0.61.9
Delay discount exponential model param1.51.64.21.21.4-0.71.1-1.41.62.00.21.3-0.4-0.71.50.8-1.8
Delay discount hyperbolic model param0.80.82.40.80.9-0.30.7-1.01.21.50.30.8-0.1-0.31.10.7-1.4
Fecal boli incidents, locomotor time 10.30.31.7-0.4-0.20.6-0.10.1-0.2-0.51.3-0.10.20.4-0.5-1.00.1
Change in fecal boli incidents, locomotor task2.32.24.3-1.5-1.90.6-1.71.7-1.8-1.5-0.8-1.71.01.4-1.60.02.1
Time >=10cm from walls, locomotor time 10.10.10.50.30.1-0.2-0.2-0.10.30.4-0.70.1-0.6-0.10.40.7-0.1
Bouts of movement, locomotor time 10.10.10.50.30.5-0.30.5-0.30.10.70.30.2-0.4-0.30.40.20.0
Total resting periods, locomotor time 10.10.21.00.50.4-0.20.5-0.20.01.00.30.2-0.0-0.00.40.4-0.0
Rest time, locomotor task time 10.30.41.01.00.60.10.5-0.50.70.90.20.50.50.30.5-0.0-1.0
Distance moved, locomotor task time 11.01.13.00.80.7-1.60.9-0.91.00.1-1.70.9-1.2-1.60.4-0.8-0.9
Vertical activity count, locomotor time 11.31.33.90.80.8-1.70.9-0.80.80.7-2.00.9-1.7-1.80.70.1-0.3
Time >=10cm from walls, locomotor time 20.50.62.80.2-0.80.1-0.80.7-0.4-0.9-0.6-0.71.70.6-0.8-0.5-0.3
Bouts of movement, locomotor time 20.50.61.90.10.8-0.30.7-0.70.70.70.20.6-1.4-0.81.01.0-0.3
Total resting periods, locomotor time 20.40.41.60.10.6-0.40.6-0.60.60.4-0.10.4-1.3-0.70.90.9-0.1
Rest time, locomotor task time 20.50.62.20.70.7-0.60.4-0.50.51.0-1.10.6-0.7-0.21.11.5-0.1
Distance moved, locomotor task time 20.60.72.11.00.9-0.90.9-1.00.90.5-0.31.1-0.2-0.90.6-0.4-1.4
Vertical activity count, locomotor time 20.70.82.30.70.8-0.80.8-0.91.00.7-0.10.8-1.0-1.50.4-0.9-1.3
Weight adjusted by age1.41.62.31.51.5-1.51.5-1.51.40.7-0.81.5-1.1-1.41.3-0.0-1.2
Seeking ratio, delayed vs. immediate footshock0.60.76.70.0-0.40.10.10.30.10.4-0.1-0.50.80.2-1.1-2.6-0.3
Locomotion in novel chamber0.40.54.20.50.2-0.40.7-0.20.50.5-0.80.2-0.1-0.5-0.4-2.0-0.5
Locomotion in novel chamber post-restriction0.30.30.70.10.70.10.6-0.80.4-0.80.70.8-0.5-0.40.70.3-0.5
Progressive ratio0.20.20.80.1-0.30.8-0.30.2-0.6-0.30.3-0.30.70.9-0.5-0.7-0.1
Food seeking constrained by brief footshock0.50.62.6-0.8-0.60.9-0.70.5-0.7-1.11.6-0.70.50.2-0.7-0.30.0
Seeking ratio, punishment vs. effort0.10.20.5-0.7-0.50.1-0.50.5-0.3-0.30.5-0.40.1-0.2-0.20.40.4
Run reversals in cocaine runway, females3.13.15.11.82.1-1.72.2-2.12.00.9-0.32.2-2.0-1.81.5-0.8-1.7
Run reversals in cocaine runway, males1.01.01.7-0.9-1.30.5-1.31.2-1.0-1.20.0-1.21.20.9-0.90.30.9
Latency to leave start box in cocaine runway0.10.21.00.40.1-0.60.1-0.10.10.0-1.00.1-0.1-0.40.30.70.1
Latency to leave start box in cocaine runway, F0.30.42.20.60.4-0.90.2-0.40.00.1-1.50.4-0.3-0.40.50.80.2
Latency to leave start box in cocaine runway, M0.20.21.1-0.30.10.40.3-0.10.30.81.00.10.1-0.2-0.2-0.9-0.3
Cd content in liver0.60.63.20.10.4-1.00.3-0.70.70.9-0.50.4-1.8-1.30.4-0.40.0
Co content in liver0.30.31.1-0.30.00.10.2-0.60.9-0.20.7-0.3-0.8-1.00.3-0.1-0.9
Cu content in liver0.50.61.8-0.30.5-0.20.3-0.91.00.81.00.4-1.3-1.00.60.3-0.9
Fe content in liver1.72.03.7-1.9-1.71.0-1.41.5-1.6-1.01.1-1.60.30.9-1.8-1.21.9
K content in liver1.21.23.51.01.30.61.5-0.80.81.21.51.30.1-0.01.20.4-1.9
Mg content in liver1.51.53.11.21.5-0.41.8-1.11.31.30.11.5-0.9-0.91.60.7-1.7
Mn content in liver0.40.41.70.20.5-0.30.7-0.50.80.2-0.30.4-1.3-1.00.60.2-0.6
Na content in liver1.61.73.1-1.0-1.01.5-1.21.5-1.6-1.71.4-1.01.81.6-0.70.90.9
Rb content in liver0.81.04.3-1.3-0.62.0-0.40.9-0.5-0.42.1-0.70.91.1-0.40.1-0.2
Se content in liver0.10.10.8-0.30.1-0.1-0.10.0-0.10.90.30.3-0.60.00.0-0.30.5
Sr content in liver0.70.76.10.2-0.4-0.70.2-0.20.60.0-0.6-0.50.2-0.6-0.9-2.5-0.8
Zn content in liver0.50.52.4-0.20.21.0-0.10.3-0.11.41.60.10.10.40.41.1-0.3