Best TWAS P=1.923189e-08 · Best GWAS P=2.519445e-07 conditioned to 0.0003551019
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Kctd18 | gene expression | ENSRNOG00000027091 | 0.08 | 0.03 | enet | 488 | 0.04 | 1.9e-05 | -4.2 | 5.6 | 1.9e-08 | -0.31 | 0.87 | 0.12 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.