Best TWAS P=5.73e-09 · Best GWAS P=6.13e-08 conditioned to 3.02e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Mtus2 | gene expression | ENSRNOG00000032410 | 0.04 | 1 | 0.04 | 7.3e-05 | 5.1 | 3.32e-07 | 0.21 | FALSE |
| Adipose | Slc7a1 | mRNA stability | ENSRNOG00000000924 | 0.08 | 1 | 0.06 | 4.2e-07 | 5.32 | 1.06e-07 | 0.88 | FALSE |
| Brain | Slc7a1 | mRNA stability | ENSRNOG00000000924 | 0.21 | 174 | 0.16 | 4.3e-15 | 5.82 | 5.73e-09 | 0.74 | TRUE |
| NAcc | Slc7a1 | mRNA stability | ENSRNOG00000000924 | 0.11 | 1 | 0.12 | 4.2e-09 | 5.13 | 2.84e-07 | 0.76 | FALSE |
| PL | Slc7a1 | mRNA stability | ENSRNOG00000000924 | 0.13 | 1 | 0.12 | 4.3e-09 | 5.1 | 3.32e-07 | 0.73 | FALSE |