Nudt4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000009094 0.1 0.04 9.1e-10 0.04 0.07 0.08 0.08 1.1e-05 1.0e-08 7.7e-09 4.4e-09
2 BLA gene expression ENSRNOG00000009094 0.46 0.09 0.0e+00 0.35 0.37 0.38 0.38 2.3e-19 6.2e-21 2.5e-21 1.9e-21
3 Brain gene expression ENSRNOG00000009094 0.86 0.03 0.0e+00 0.63 0.7 0.73 0.74 7.2e-75 2.9e-91 3.3e-99 8.6e-100
4 Eye gene expression ENSRNOG00000009094 0.69 0.12 1.2e-06 0.26 0.25 0.23 0.23 5.7e-05 9.6e-05 1.8e-04 2.1e-04
5 IL gene expression ENSRNOG00000009094 0.62 0.1 1.9e-12 0.26 0.41 0.38 0.36 5.1e-07 5.1e-11 5.8e-10 2.0e-09
6 LHb gene expression ENSRNOG00000009094 0.75 0.11 8.8e-10 0.3 0.19 0.25 0.25 6.1e-08 3.0e-05 1.1e-06 1.5e-06
7 Liver gene expression ENSRNOG00000009094 0.1 0.05 1.1e-05 0.06 0.04 0.06 0.05 4.5e-07 3.7e-05 4.1e-07 1.2e-06
8 NAcc gene expression ENSRNOG00000009094 0.47 0.08 0.0e+00 0.46 0.45 0.46 0.46 5.8e-38 6.4e-37 1.5e-37 1.7e-37
9 OFC gene expression ENSRNOG00000009094 0.86 0.06 2.8e-14 0.41 0.34 0.38 0.39 7.9e-11 6.8e-09 6.5e-10 2.3e-10
10 PL gene expression ENSRNOG00000009094 0.68 0.09 0.0e+00 0.51 0.53 0.55 0.55 3.4e-44 4.6e-47 1.1e-49 4.0e-49

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.51.83.1-0.8-1.7-0.7-1.8-1.2-1.7-0.7-1.2-1.7-1.1
BMI without tail0.71.58.9-1.40.51.2-0.10.6-0.1-3.00.9-0.11.0
Body weight3.213.425.6-2.53.74.73.13.12.8-5.13.52.84.4
Epididymis fat weight0.10.10.9-0.20.00.50.1-0.3-0.2-0.90.2-0.2-0.1
Glucose0.20.30.60.2-0.7-0.7-0.8-0.4-0.70.0-0.6-0.7-0.7
Heart weight0.30.41.90.5-0.3-0.50.0-1.40.01.10.10.0-0.2
Left kidney weight0.82.34.1-0.51.62.01.61.41.5-1.31.51.51.8
Right kidney weight1.33.66.0-1.12.02.41.81.81.8-1.81.91.82.2
Tail length8.024.234.7-2.45.75.64.74.84.5-5.25.04.55.9
Length with tail9.835.849.8-2.66.97.16.15.65.8-5.66.15.87.1
Length without tail3.88.412.5-1.13.23.53.32.53.1-1.73.03.13.4
Liver weight, left0.30.52.0-1.4-0.5-0.2-0.5-0.2-0.90.5-0.6-0.9-0.1
Liver weight, right1.32.23.5-1.91.51.81.41.61.30.01.01.31.9
Parametrial fat weight0.91.73.91.1-1.3-1.4-0.8-2.0-1.01.6-0.9-1.0-1.6
Retroperitoneal fat weight0.31.14.4-2.10.91.40.60.80.4-0.50.40.41.4
Intraocular pressure0.40.61.3-0.7-0.7-0.5-1.1-0.4-1.0-0.3-0.8-1.0-0.7
Extensor digitorum longus weight0.10.31.1-0.40.40.60.30.40.2-1.10.30.20.6
Soleus weight0.41.32.71.6-1.0-1.2-1.0-1.5-0.80.6-1.1-0.8-1.3
Tibialis anterior weight0.41.43.41.5-1.3-1.1-0.7-1.9-1.0-0.1-0.6-1.0-1.5
Tibia length1.43.86.1-1.52.12.41.91.21.5-2.52.21.52.4
Number of licking bursts2.32.73.70.5-1.7-1.8-1.9-1.7-1.90.6-1.8-1.9-1.7
Food consumed during 24 hour testing period0.60.75.00.70.40.30.50.50.2-2.20.70.20.4
Times rat made contact with spout1.82.13.50.9-1.4-1.9-1.7-1.4-1.70.4-1.0-1.7-1.6
Mean time between licks in bursts0.20.30.6-0.5-0.8-0.1-0.5-0.0-0.50.7-0.8-0.5-0.3
Mean num. licks in bursts0.10.10.30.30.30.00.30.30.30.20.60.30.1
Std. dev. time between licks in bursts0.91.02.90.2-1.3-0.6-0.8-0.8-0.81.7-1.1-0.8-1.1
Water consumed over 24 hours0.50.63.81.20.1-0.4-0.0-0.3-0.3-1.90.4-0.3-0.2
Indifference point 0 sec1.11.84.10.71.41.41.60.41.6-0.92.01.61.0
Indifference point AUC0.40.50.9-0.60.90.80.80.60.8-0.20.70.80.9
Indifference point function ln k0.40.61.01.0-0.8-0.8-0.8-0.8-0.8-0.4-0.6-0.8-0.9
Indifference point function log k0.40.61.01.0-0.8-0.8-0.8-0.8-0.8-0.4-0.6-0.8-0.9
Delay discounting total patch changes 0 sec1.11.83.90.61.41.41.60.51.6-0.82.01.61.0
Delay discounting total patch changes 12 sec0.20.30.7-0.70.40.80.50.30.40.50.60.40.3
Delay discounting total patch changes 18 sec0.91.21.90.11.41.31.10.81.2-1.21.21.21.0
Delay discounting total patch changes 24 sec1.51.94.0-0.11.41.61.31.01.4-1.62.01.41.1
Delay discounting total patch changes 6 sec0.10.20.50.70.10.30.2-0.10.2-0.50.70.2-0.2
Delay discounting time to switch 0 sec0.10.20.6-0.40.30.40.30.40.40.80.00.40.2
Delay discounting water rate 0 sec0.40.61.2-0.5-0.8-0.6-1.0-1.1-1.0-0.2-0.4-1.0-0.5
Delay discounting water rate 12 sec0.10.21.4-0.20.30.20.10.20.1-1.20.50.10.4
Delay discounting water rate 18 sec0.50.71.4-0.9-0.8-0.7-1.1-0.2-1.2-0.4-0.9-1.2-0.3
Delay discounting water rate 24 sec0.20.20.9-0.8-0.10.1-0.3-0.3-0.4-1.00.1-0.40.3
Delay discounting water rate 6 sec0.60.94.8-2.2-0.00.3-0.80.3-0.8-1.20.0-0.80.7
Locomotor activity0.10.21.2-1.1-0.10.1-0.4-0.4-0.30.5-0.2-0.30.4
Locomotor testing distance1.52.53.8-0.3-1.7-1.5-1.9-1.8-1.91.1-1.6-1.9-1.4
Locomotor testing rearing0.60.92.0-0.8-0.9-0.8-1.2-0.7-1.40.0-0.9-1.4-0.6
Light reinforcement 10.20.30.9-0.4-0.5-0.4-0.7-0.0-0.8-0.0-0.9-0.8-0.3
Light reinforcement 20.10.10.60.50.30.20.2-0.20.4-0.80.20.40.1
Reaction time number correct1.21.72.70.3-1.2-1.6-1.6-1.3-1.50.5-1.4-1.5-1.2
Reaction time mean minus median0.60.81.50.30.91.01.20.71.10.21.01.10.7
Reaction time mean minus median AUC0.30.40.70.20.50.70.80.60.80.40.60.80.5
Reaction time num false alarms0.20.30.80.90.40.20.70.20.6-0.10.70.60.1
Reaction time num false alarms AUC0.00.10.30.6-0.0-0.20.20.10.10.10.40.1-0.2
Reaction time trials correct on left1.21.72.70.3-1.2-1.6-1.6-1.3-1.50.5-1.4-1.5-1.2
Reaction time trials on left1.31.92.90.4-1.3-1.7-1.7-1.4-1.60.6-1.4-1.6-1.3
Reaction time mean0.10.20.4-0.3-0.5-0.3-0.4-0.6-0.50.4-0.4-0.5-0.3
Reaction time mean AUC0.00.00.2-0.40.00.20.1-0.2-0.00.1-0.0-0.00.2
Median of all reaction times0.20.30.5-0.5-0.6-0.4-0.6-0.7-0.60.2-0.6-0.6-0.3
Reaction time omissions2.94.06.82.6-2.1-2.2-1.6-1.8-1.61.3-2.1-1.6-2.5
Reaction time false alarm rate0.40.51.10.30.60.71.10.70.9-0.21.00.90.5
Reaction time premature initiation rate1.41.93.4-1.5-1.3-0.8-1.8-0.5-1.71.5-1.5-1.7-0.7
Reaction time premature initiations1.72.44.9-1.4-1.5-1.2-2.2-0.7-2.01.4-1.7-2.0-0.9
Std. dev. reaction times0.10.20.50.40.20.30.50.10.40.70.20.40.2
Reaction time trials completed1.31.92.90.4-1.3-1.7-1.7-1.4-1.60.6-1.4-1.6-1.3
Reaction time trials AUC1.31.83.10.1-1.3-1.7-1.8-1.3-1.60.5-1.4-1.6-1.2
Social response proportion0.10.20.5-0.7-0.1-0.2-0.1-0.6-0.20.7-0.2-0.20.3
Social responses1.01.34.7-2.2-0.8-0.6-1.0-0.4-1.11.6-1.0-1.10.0
Social time0.30.40.6-0.6-0.6-0.6-0.5-0.5-0.80.7-0.7-0.8-0.5
Conditioned locomotion0.60.71.70.50.90.51.30.11.10.10.81.10.7
Cocaine response after cond. corrected0.10.10.70.3-0.1-0.2-0.2-0.0-0.1-0.9-0.0-0.1-0.0
Cocaine response after cond. not corrected0.10.10.30.3-0.3-0.4-0.4-0.2-0.4-0.6-0.3-0.4-0.3
Cocaine response before conditioning0.40.50.8-0.1-0.8-0.7-0.7-0.3-0.90.8-0.9-0.9-0.7
Saline control response0.70.91.3-0.61.11.11.11.11.0-0.50.91.01.1
Condit. Reinf. active minus inactive responses0.20.31.9-0.6-0.30.4-0.00.10.21.4-0.10.2-0.1
Condit. Reinf. active-inactive response ratio0.40.40.9-0.20.31.00.50.50.8-0.20.90.80.3
Condit. Reinf. active responses0.30.53.0-0.2-0.8-0.1-0.3-0.2-0.21.7-0.7-0.2-0.5
Condit. Reinf. inactive responses1.01.23.40.5-1.2-1.1-0.7-0.6-0.81.9-1.5-0.8-1.0
Condit. Reinf. lever presses0.50.72.7-1.60.41.20.31.30.40.20.10.40.8
Condit. Reinf. lever reinforcers received0.40.63.40.1-0.9-0.2-0.4-0.5-0.21.8-0.8-0.2-0.7
Pavlov. Cond. lever latency0.20.21.1-0.30.5-0.00.20.40.1-1.00.30.10.7
Pavlov. Cond. magazine entry latency0.20.20.60.2-0.7-0.3-0.6-0.2-0.60.1-0.5-0.6-0.8
Pavlov. Cond. change in total contacts0.10.10.3-0.2-0.10.50.1-0.50.10.30.20.1-0.2
Pavlov. Cond. index score0.10.20.40.2-0.5-0.1-0.4-0.4-0.30.5-0.3-0.3-0.7
Pavlov. Cond. latency score0.00.10.1-0.1-0.30.2-0.2-0.2-0.20.3-0.1-0.2-0.4
Pavlov. Cond. lever contacts0.71.02.10.4-1.2-0.6-0.9-1.1-0.81.4-1.0-0.8-1.3
Pavlov. Cond. magazine entry number1.31.52.5-0.01.51.11.61.01.5-0.61.31.51.4
Pavlov. Cond. intertrial magazine entries0.30.40.6-0.50.40.70.70.80.60.00.40.60.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.2-0.40.0-0.3-0.3-0.20.4-0.2-0.2-0.5
Pavlov. Cond. response bias1.01.42.30.6-1.4-0.9-1.1-1.3-1.01.4-1.1-1.0-1.5
Conditioned reinforcement - actives1.41.33.4-1.91.21.20.91.20.90.00.50.91.7
Conditioned reinforcement - inactives0.91.13.0-1.61.40.70.71.00.7-0.20.20.71.7
Conditioned locomotion1.11.32.6-0.81.51.31.21.01.2-0.61.01.21.6
Intermittent access intake day 1-15 change0.50.52.6-1.6-0.20.2-0.70.9-0.70.1-0.5-0.70.3
Intermittent access intake escalation0.60.61.8-1.3-0.6-0.2-0.90.5-1.00.4-0.8-1.0-0.1
Intermittent access intake escalation 20.30.30.8-0.9-0.4-0.3-0.80.1-0.80.1-0.6-0.8-0.1
Intermitt. access day 1 inactive lever presses0.30.30.80.70.40.20.9-0.10.80.20.80.80.1
Intermitt. access day 15 inactive lever presses0.70.81.4-0.21.00.81.20.71.20.00.91.21.0
Intermitt. access escalation Index0.20.10.4-0.2-0.6-0.2-0.5-0.1-0.40.4-0.3-0.4-0.4
Intermittent access day 1 total infusions1.61.82.7-0.41.51.51.11.61.2-1.71.21.21.6
Intermittent access day 15 total infusions1.61.83.8-1.51.41.60.71.90.8-1.41.00.81.8
Intermittent access terminal intake (last 3 days)1.92.03.4-1.31.51.81.01.81.1-1.21.31.11.9
Intermittent access total infusions1.82.03.2-0.81.51.81.21.71.3-1.51.31.31.7
Intermittent access day 1 locomotion2.62.74.00.32.01.51.71.21.7-2.01.61.71.8
Intermittent access day 15 total locomotion4.85.27.9-0.32.82.22.32.22.3-2.52.22.32.6
Intermittent access total locomotion4.65.27.1-0.22.72.42.32.12.3-2.62.22.32.6
Intermittent access standard deviation0.20.31.2-1.10.40.5-0.00.7-0.1-0.3-0.1-0.10.7
Cocaine induced anxiety0.80.94.02.0-0.5-0.90.1-1.30.20.7-0.70.2-1.1
Post-drug Anxiety0.40.52.61.6-0.5-0.50.2-0.60.20.5-0.30.2-1.0
Baseline Anxiety0.50.51.3-0.40.60.90.51.10.5-0.71.00.50.7
Lifetime Intake1.21.32.3-0.61.31.51.01.21.1-1.01.01.11.4
Incentive Sensitization - Responses1.31.34.6-2.21.11.00.61.60.6-0.50.30.61.5
Incentive Sensitization - Breakpoint1.21.24.3-2.11.00.90.51.60.5-0.50.30.51.4
Progressive ratio test 1 active lever presses3.43.55.5-1.02.22.21.71.91.6-2.11.61.62.3
Progressive ratio test 1 breakpoint2.72.84.7-1.11.92.01.51.71.4-1.81.41.42.2
Progressive ratio test 1 inactive lever presses1.31.32.4-0.91.51.21.11.41.0-0.90.81.01.6
Progressive ratio test 2 active lever presses1.81.94.4-2.11.41.50.91.80.9-0.90.70.91.9
Progressive ratio test 2 breakpoint1.61.85.1-2.31.31.50.71.80.7-0.80.60.71.8
Progressive ratio test 2 inactive lever presses1.11.32.6-1.11.51.01.11.21.1-0.50.81.11.6
Total sessions with >9 infusions0.60.61.2-0.51.01.00.70.70.7-0.70.40.71.1
Short access day 1 total inactive lever presses0.10.10.30.60.1-0.40.1-0.30.00.3-0.60.0-0.1
Short access day 10 total inactive lever presses0.60.71.20.2-1.1-1.0-0.8-0.1-0.90.7-0.8-0.9-1.1
Short access day 1 total infusions0.30.31.4-1.20.40.60.30.50.20.4-0.30.20.8
Short access day 10 total infusions1.41.62.5-0.21.41.61.30.91.3-1.51.41.31.4
Short access total infusions0.30.40.8-0.70.60.90.50.60.5-0.30.30.50.8
Short access day 1 locomotion0.70.71.3-1.00.91.00.81.00.7-0.30.40.71.2
Short access day 10 total locomotion0.70.81.10.11.01.01.00.31.0-0.81.11.01.0
Short access total locomotion2.12.13.1-0.51.71.61.71.01.7-0.91.41.71.8
Compulsive drug intake0.40.31.51.2-0.2-0.30.5-0.80.30.70.10.3-0.6
One hour access (0.3 mA shock)1.82.14.0-1.61.61.81.21.71.2-0.71.11.22.0
One hour access (shock baseline)2.02.34.5-1.81.61.70.82.11.0-1.31.01.02.1
Number of responses in last shaping day0.70.71.1-0.50.91.00.90.50.90.11.00.91.0
Context. condit. distance diff. score1.21.42.20.11.21.31.20.61.3-1.51.51.31.1
Locomotion velocity, session 11.31.43.9-0.2-1.1-1.1-1.2-0.4-1.12.0-1.3-1.1-1.0
Locomotion distance, session 10.81.05.70.0-0.8-0.6-0.8-0.4-0.52.4-1.2-0.5-0.8
Locomotion velocity, session 22.73.24.7-0.32.02.02.11.82.2-0.61.82.21.9
Locomotion distance, session 20.30.43.4-0.4-0.2-0.1-0.3-0.3-0.21.8-0.7-0.2-0.1
Locomotion velocity, session 32.63.04.1-0.62.01.92.01.52.0-0.82.02.01.9
Locomotion distance, session 30.00.00.10.30.20.30.1-0.20.2-0.10.20.2-0.0
Stereotopy head waving bouts, day 31.41.73.8-1.91.51.30.91.41.10.30.91.11.8
Stereotopy head waving duration, day 31.62.03.3-1.61.61.41.21.71.3-0.41.31.31.8
Locomotion velocity, session 70.20.21.2-0.60.20.20.4-0.10.21.10.10.20.4
Locomotion distance, session 70.30.42.10.8-0.1-0.40.2-0.60.21.4-0.30.2-0.4
Stereotopy head waving bouts, day 71.51.72.6-0.71.41.51.51.21.4-0.61.61.41.4
Stereotopy head waving duration, day 70.30.30.8-0.10.50.60.80.40.7-0.50.90.70.4
Locomotion velocity, session 82.93.55.4-0.81.92.31.82.21.9-1.61.81.92.0
Locomotion distance, session 80.71.01.9-1.01.21.30.80.51.1-0.00.91.11.4
Degree of sensitization distance0.10.11.00.2-0.2-0.40.0-0.2-0.01.0-0.4-0.0-0.1
Degree of sensitization stereotypy0.70.71.50.70.70.81.20.41.0-0.61.21.00.4
Condit. Reinf. active minus inactive responses3.94.35.9-0.2-2.4-2.2-2.1-1.6-2.32.4-2.1-2.3-2.2
Condit. Reinf. active-inactive response ratio4.34.66.20.0-2.5-2.3-2.3-2.0-2.41.9-2.0-2.4-2.3
Condit. Reinf. active responses4.45.37.4-0.2-2.7-2.5-2.3-1.7-2.72.3-2.4-2.7-2.5
Condit. Reinf. inactive responses0.50.61.10.2-1.0-0.9-0.6-0.2-0.90.7-1.0-0.9-0.9
Incentive salience index mean4.85.78.0-0.8-2.6-2.5-2.5-1.7-2.82.8-2.5-2.8-2.3
Condit. Reinf. lever presses1.62.24.5-1.0-1.4-1.3-1.4-0.9-1.72.1-1.6-1.7-1.2
Time in familiar zone, hab. session 10.00.00.10.1-0.20.1-0.1-0.1-0.10.1-0.0-0.1-0.2
Time in novel zone, hab. session 11.31.35.12.3-0.9-1.3-0.4-1.5-0.40.3-0.7-0.4-1.4
Total zone transitions, hab. session 11.52.110.6-1.9-0.7-0.6-1.1-0.5-1.03.3-1.6-1.0-0.2
Total locomotion distance, hab. session 12.02.812.3-2.7-0.7-0.4-1.30.2-1.13.5-1.9-1.10.0
Locomotion velocity, hab. session 12.84.014.7-3.8-0.6-0.3-1.50.6-1.43.7-2.1-1.40.4
Time in familiar zone, hab. session 20.00.00.10.1-0.10.1-0.20.30.20.3-0.20.20.1
Time in novel zone, hab. session 20.20.20.60.4-0.4-0.5-0.0-0.8-0.40.1-0.1-0.4-0.5
Total zone transitions, hab. session 22.22.911.00.0-1.5-1.5-1.5-1.5-1.33.3-1.9-1.3-1.5
Total locomotion distance, hab. session 24.15.413.5-1.9-2.1-1.7-2.5-1.2-2.43.7-2.8-2.4-1.4
Locomotion velocity, hab. session 24.05.413.1-2.2-2.0-1.7-2.5-1.1-2.53.6-2.8-2.5-1.2
Novel to familiar place preference ratio1.61.63.3-0.21.31.41.31.81.3-1.21.21.31.3
Novelty place preference1.21.22.9-0.11.01.21.11.71.0-1.21.11.01.0
Time in novel zone, NPP test0.80.91.80.30.80.91.01.30.9-1.00.90.90.7
Total zone transitions, NPP test0.60.86.0-0.7-0.2-0.3-0.5-0.7-0.32.4-0.9-0.3-0.2
Total locomotion distance, NPP test1.62.29.2-2.8-0.30.0-1.00.3-0.83.0-1.5-0.80.4
Locomotion velocity, NPP test1.52.18.8-3.0-0.10.2-0.80.5-0.72.8-1.3-0.70.6
Pavlov. Cond. lever latency0.40.51.20.30.70.70.50.20.8-1.10.60.80.7
Pavlov. Cond. magazine entry latency2.93.75.51.2-2.2-2.2-1.8-1.8-1.81.9-1.9-1.8-2.3
Pavlov. Cond. change in total contacts2.62.84.40.8-1.9-1.8-1.4-1.5-1.81.4-1.9-1.8-2.1
Pavlov. Cond. index score2.43.14.60.3-2.0-2.0-1.6-1.3-1.82.1-1.9-1.8-2.0
Pavlov. Cond. latency score1.72.23.7-0.0-1.6-1.6-1.4-1.0-1.61.9-1.6-1.6-1.6
Pavlov. Cond. lever contacts0.70.82.0-0.7-0.8-0.8-0.6-0.2-1.01.4-1.0-1.0-0.7
Pavlov. Cond. magazine entry number3.03.85.4-1.32.22.31.81.81.8-2.02.01.82.3
Pavlov. Cond. intertrial magazine entries1.11.34.21.6-1.1-1.2-0.6-2.0-0.70.1-0.6-0.7-1.3
Pavlov. Cond. lever-magazine prob. diff.2.22.85.00.3-1.9-1.8-1.4-1.4-1.72.2-1.8-1.7-1.9
Pavlov. Cond. response bias2.73.34.40.4-2.0-2.1-1.6-1.5-1.92.0-1.9-1.9-2.1
Bone: apparent density0.10.20.70.20.4-0.10.4-0.50.3-0.20.90.30.2
Bone surface0.10.10.4-0.3-0.2-0.4-0.3-0.6-0.20.3-0.1-0.2-0.0
Bone volume0.00.10.5-0.1-0.1-0.3-0.2-0.7-0.1-0.10.3-0.10.0
Bone: connectivity density0.10.20.6-0.70.6-0.00.30.50.30.00.50.30.8
Bone: cortical apparent density0.20.30.80.50.60.40.90.10.60.20.20.60.3
Bone: cortical area0.50.82.21.0-0.8-1.1-0.7-1.5-0.80.1-0.4-0.8-1.0
Bone: cortical porosity3.74.05.4-0.62.12.32.21.82.3-1.32.12.32.1
Bone: cortical porosity1.81.92.8-0.81.41.71.51.11.6-0.81.51.61.6
Bone: cortical thickness0.10.21.41.20.2-0.10.6-0.50.40.00.40.4-0.1
Bone: cortical thickness0.30.31.01.0-0.6-0.7-0.2-0.6-0.4-0.1-0.1-0.4-0.6
Bone: cortical tissue density0.30.30.90.40.70.51.00.20.70.10.30.70.5
Bone: elastic displacement0.30.30.80.2-0.8-0.3-0.40.2-0.50.4-0.9-0.5-0.7
Bone: elastic work0.30.42.11.40.10.30.80.00.7-0.20.40.7-0.2
Bone: endosteal estimation0.81.84.60.4-1.4-1.5-1.6-2.1-1.4-0.2-0.8-1.4-1.3
Bone: endosteal perimeter1.53.15.50.2-1.8-1.9-2.3-2.3-2.1-0.4-1.2-2.1-1.6
Bone: final force1.11.87.12.3-0.8-1.4-0.4-2.7-0.50.1-0.0-0.5-1.4
Bone: final moment1.11.97.02.2-0.9-1.5-0.6-2.7-0.60.4-0.2-0.6-1.5
Bone: marrow area0.81.74.30.5-1.3-1.4-1.6-2.1-1.3-0.3-0.7-1.3-1.3
Bone: maximum diameter1.12.04.40.7-1.5-1.7-1.5-2.1-1.5-0.1-0.9-1.5-1.4
Bone: maximum force0.50.93.31.8-0.6-0.8-0.2-1.8-0.20.1-0.0-0.2-1.0
Bone: maximum moment0.61.13.61.8-0.9-1.1-0.5-1.9-0.40.5-0.3-0.4-1.2
Bone: minimum diameter0.91.75.61.3-1.3-1.3-1.2-2.4-1.1-0.0-0.5-1.1-1.4
Bone: periosteal estimation0.81.64.91.0-1.2-1.5-1.3-2.2-1.2-0.2-0.5-1.2-1.3
Bone: periosteal perimeter1.11.84.40.5-1.3-1.6-1.5-2.1-1.50.2-0.8-1.5-1.3
Bone: post-yield work0.60.83.82.0-0.6-1.1-0.7-1.0-0.4-0.3-0.3-0.4-1.0
Bone: stiffness0.50.83.91.70.0-0.50.4-2.00.40.70.40.4-0.4
Bone: tissue strength0.20.20.70.60.1-0.3-0.1-0.80.20.7-0.10.2-0.2
Bone: trabecular number0.00.10.3-0.20.0-0.5-0.2-0.3-0.3-0.30.2-0.30.0
Bone: trabecular spacing0.10.21.1-0.3-0.10.50.11.10.2-0.1-0.10.20.1
Bone: trabecular thickness0.10.10.40.60.2-0.10.2-0.30.2-0.70.60.20.1
Bone: trabecular tissue density0.50.81.5-0.11.01.01.20.41.10.30.81.10.8
Breakpoint value in progressive ratio session1.82.04.8-0.7-1.3-1.4-1.4-0.9-1.41.8-2.2-1.4-0.9
Distance traveled before self-admin0.50.51.8-1.3-0.5-0.3-0.80.3-0.80.9-0.8-0.8-0.0
Distance traveled after self-admin0.20.20.90.30.20.00.5-1.00.50.80.00.50.1
Delta time in closed arm before/after self-admin1.31.22.2-0.2-1.4-0.9-1.5-0.8-1.50.7-0.8-1.5-1.2
Delta time in open arm before/after self-admin0.20.20.30.30.40.40.60.30.6-0.20.60.60.3
Diff in mean of infusions in LGA sessions1.01.21.80.5-1.3-1.0-1.1-0.6-1.11.4-1.1-1.1-1.3
Extinction: sum of active levers before priming0.40.41.01.0-0.7-0.7-0.4-0.8-0.40.5-0.6-0.4-0.9
Active lever presses in extinction session 62.62.53.7-0.7-1.5-1.6-1.9-1.4-1.91.6-1.9-1.9-1.1
Delta distance traveled before/after self-admin0.30.30.60.70.50.30.8-0.70.80.20.30.80.3
Delta ambulatory time before/after self-admin0.60.62.71.60.1-0.10.7-1.30.70.40.30.7-0.3
Time in closed arm before self-admin0.10.10.3-0.20.40.30.40.50.3-0.20.00.30.4
Time in closed arm after self-admin1.41.52.5-0.1-1.4-1.2-1.6-0.7-1.60.6-1.4-1.6-1.2
Time in open arm before self-admin0.40.50.70.2-0.7-0.9-0.8-0.7-0.80.3-0.4-0.8-0.8
Time in open arm after self-admin0.10.10.40.40.10.00.3-0.20.30.00.60.3-0.1
Sum of active levers in priming session hrs 5-62.62.65.7-0.7-1.5-1.6-1.7-1.1-1.72.1-2.4-1.7-1.1
Time to tail flick, vehicle, before self-admin1.41.42.91.5-1.0-1.7-1.2-1.0-1.20.2-1.1-1.2-1.3
Time to tail flick, vehicle, after self-admin0.80.91.50.4-1.2-1.0-1.0-0.9-1.00.9-0.4-1.0-1.1
Time to tail flick, test, before self-admin0.30.30.91.0-0.1-0.6-0.2-0.8-0.2-0.40.4-0.2-0.5
Time to tail flick, test, after self-admin0.60.61.0-0.4-0.7-0.8-1.0-0.5-1.00.6-0.7-1.0-0.6
Delta time to tail flick, vehicle, before/after SA0.30.20.6-0.4-0.8-0.1-0.6-0.2-0.60.6-0.2-0.6-0.5
Delta time to tail flick, test, before/after SA0.20.20.6-0.70.20.60.30.60.30.30.30.30.4
Ambulatory time before self-admin0.40.42.3-1.50.30.4-0.31.1-0.2-0.0-0.3-0.20.7
Ambulatory time after self-admin0.10.10.30.20.1-0.00.3-0.60.30.5-0.30.30.2
Total heroin consumption2.63.24.7-0.0-1.9-2.0-1.8-1.6-1.92.2-2.1-1.9-1.7
Area under the delay curve0.60.72.41.0-0.4-0.40.3-1.50.41.40.50.4-0.7
Delay disc. indifference point, 0s delay0.50.51.0-0.80.50.70.70.20.81.00.70.80.6
Delay disc. indifference point, 16s delay1.11.14.31.6-0.8-0.9-0.1-2.10.01.20.10.0-1.1
Delay disc. indifference point, 2s delay0.30.40.9-0.70.30.50.60.20.60.90.80.60.4
Delay disc. indifference point, 24s delay0.60.51.51.20.4-0.10.6-0.70.8-0.31.20.80.1
Delay disc. indifference point, 4s delay0.20.20.50.5-0.10.10.3-0.20.40.70.50.4-0.4
Delay disc. indifference point, 8s delay0.60.61.81.30.10.00.8-1.10.80.80.70.8-0.5
Delay discount exponential model param0.60.61.7-1.10.20.3-0.51.3-0.5-1.1-0.7-0.50.6
Delay discount hyperbolic model param0.40.41.2-0.70.10.1-0.41.0-0.5-1.1-0.7-0.50.4
Fecal boli incidents, locomotor time 10.20.20.9-0.00.5-0.00.00.30.0-1.00.60.00.4
Change in fecal boli incidents, locomotor task1.41.33.91.9-0.9-0.90.0-2.0-0.21.2-0.5-0.2-1.5
Time >=10cm from walls, locomotor time 10.10.10.40.1-0.7-0.0-0.2-0.4-0.20.5-0.2-0.2-0.5
Bouts of movement, locomotor time 10.10.20.5-0.2-0.2-0.5-0.6-0.5-0.40.1-0.7-0.40.1
Total resting periods, locomotor time 10.10.10.3-0.1-0.1-0.5-0.5-0.3-0.20.2-0.5-0.20.2
Rest time, locomotor task time 10.20.20.6-0.70.30.50.30.80.4-0.30.40.40.7
Distance moved, locomotor task time 10.20.20.8-0.9-0.40.0-0.3-0.2-0.30.8-0.2-0.3-0.3
Vertical activity count, locomotor time 11.21.32.1-0.4-1.3-1.0-1.3-1.1-1.21.5-1.0-1.2-1.1
Time >=10cm from walls, locomotor time 20.50.51.40.9-0.9-0.6-0.5-0.5-0.40.8-0.3-0.4-1.2
Bouts of movement, locomotor time 20.40.51.0-0.90.70.90.60.60.6-0.50.30.61.0
Total resting periods, locomotor time 20.20.20.5-0.70.30.60.30.20.3-0.20.00.30.6
Rest time, locomotor task time 20.80.91.5-0.0-1.2-0.8-1.0-0.6-1.10.9-1.2-1.1-1.1
Distance moved, locomotor task time 20.50.61.2-1.10.70.90.61.10.7-0.10.40.70.9
Vertical activity count, locomotor time 20.40.51.3-1.10.60.80.40.80.4-0.30.60.40.9
Weight adjusted by age0.30.32.3-1.50.20.2-0.30.6-0.10.2-0.1-0.10.7
Seeking ratio, delayed vs. immediate footshock0.10.10.4-0.0-0.2-0.6-0.5-0.5-0.4-0.3-0.3-0.4-0.3
Locomotion in novel chamber0.40.51.0-0.1-0.5-0.9-0.8-0.6-0.90.1-1.0-0.9-0.5
Locomotion in novel chamber post-restriction0.81.01.6-1.11.11.00.81.30.7-1.10.40.71.3
Progressive ratio0.70.81.6-0.20.91.01.30.51.1-0.11.11.10.7
Food seeking constrained by brief footshock2.53.14.5-0.41.92.12.11.31.9-1.42.01.91.8
Seeking ratio, punishment vs. effort0.00.00.20.30.10.10.10.00.2-0.40.30.20.1
Run reversals in cocaine runway, females1.01.05.6-2.40.90.80.01.10.0-0.40.20.01.4
Run reversals in cocaine runway, males0.70.72.11.4-0.9-0.9-0.6-0.9-0.60.2-0.3-0.6-1.3
Latency to leave start box in cocaine runway1.41.52.00.4-1.4-1.4-1.3-1.0-1.31.1-1.4-1.3-1.3
Latency to leave start box in cocaine runway, F1.61.82.70.2-1.6-1.5-1.3-1.3-1.31.6-1.3-1.3-1.4
Latency to leave start box in cocaine runway, M0.40.31.6-0.20.70.30.20.80.2-1.3-0.00.20.7
Cd content in liver0.20.20.5-0.7-0.3-0.3-0.5-0.7-0.60.1-0.1-0.60.1
Co content in liver1.11.32.8-1.31.11.10.61.20.6-1.71.10.61.4
Cu content in liver1.82.23.8-1.51.51.60.81.51.1-2.01.41.11.9
Fe content in liver0.30.41.01.00.50.20.4-0.70.8-0.30.70.80.2
K content in liver9.59.513.6-2.43.53.53.13.53.3-0.92.83.33.7
Mg content in liver2.82.94.6-2.11.82.01.62.01.6-0.11.21.62.1
Mn content in liver0.40.51.3-1.20.60.90.80.40.5-0.00.60.50.8
Na content in liver0.90.92.01.20.90.71.10.61.4-0.20.81.40.5
Rb content in liver3.74.66.0-0.52.42.22.32.02.2-2.12.32.22.4
Se content in liver0.10.10.2-0.10.30.40.30.10.40.30.20.40.3
Sr content in liver0.20.20.9-1.0-0.1-0.4-0.4-0.2-0.60.2-0.2-0.6-0.0
Zn content in liver2.93.25.0-0.41.82.21.81.92.1-1.21.82.11.9