Hub : Genes

Numa1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1:156326758:156333058 0.13 0.08 6.7e-12 0.1 0.1 0.1 0.1 3.2e-11 3.7e-11 4.2e-11 2.8e-11
2 Adipose intron excision ratio chr1:156327214:156333058 0.1 0.07 7.3e-08 0.07 0.06 0.06 0.06 8.0e-08 6.0e-07 2.6e-07 2.7e-07
3 Adipose mRNA stability ENSRNOG00000000417 0.1 0.06 2.6e-08 0.06 0.06 0.06 0.06 1.0e-06 9.3e-08 1.1e-07 2.1e-07
4 BLA mRNA stability ENSRNOG00000000417 0.16 0.1 6.5e-07 0.11 0.12 0.11 0.12 1.5e-06 7.7e-07 2.7e-06 7.0e-07
5 Brain gene expression ENSRNOG00000000417 0.17 0.1 5.2e-12 0.14 0.13 0.14 0.13 1.6e-12 3.0e-12 3.3e-13 4.4e-12
6 Brain intron excision ratio chr1:156326758:156333058 0.07 0.06 1.4e-05 0.06 0.06 0.06 0.06 4.7e-06 4.9e-06 4.9e-06 5.0e-06
7 Brain mRNA stability ENSRNOG00000000417 0.34 0.15 0.0e+00 0.29 0.3 0.29 0.3 8.6e-27 2.8e-28 1.9e-27 5.2e-28
8 IL intron excision ratio chr1:156326758:156333058 0.2 0.16 3.3e-03 0.1 0.1 0.1 0.12 2.3e-03 2.3e-03 2.3e-03 8.1e-04
9 Liver gene expression ENSRNOG00000000417 0.05 0.04 1.3e-04 0.03 0.03 0.03 0.03 1.5e-04 7.6e-04 2.9e-04 3.2e-04
10 Liver mRNA stability ENSRNOG00000000417 0.04 0.03 5.0e-04 0.01 0.01 0.02 0.01 2.8e-02 7.7e-03 4.6e-03 1.6e-02
11 NAcc intron excision ratio chr1:156326758:156333058 0.04 0.03 5.5e-03 0.04 0.03 0.02 0.04 4.9e-04 3.9e-03 8.9e-03 1.0e-03
12 NAcc mRNA stability ENSRNOG00000000417 0.06 0.05 3.3e-04 0.03 0.04 0.06 0.04 2.8e-03 3.5e-04 3.0e-05 4.2e-04
13 OFC gene expression ENSRNOG00000000417 0.33 0.17 1.4e-03 0.01 0.03 0.03 0.02 1.7e-01 6.1e-02 7.5e-02 1.0e-01
14 OFC mRNA stability ENSRNOG00000000417 0.3 0.16 2.1e-05 0.08 0.16 0.14 0.14 5.8e-03 1.3e-04 2.8e-04 3.3e-04
15 PL mRNA stability ENSRNOG00000000417 0.21 0.12 2.5e-12 0.14 0.15 0.15 0.14 1.5e-10 1.3e-11 1.9e-11 4.3e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.61.95.81.6-1.50.71.51.51.4-0.52.41.7-0.31.50.61.81.3-0.0
BMI without tail0.61.31.71.2-1.11.21.1-0.91.11.20.71.31.21.11.3-0.91.21.3
Body weight0.10.41.6-0.00.10.3-0.1-1.3-0.20.8-0.60.11.0-0.10.5-1.20.10.7
Epididymis fat weight0.20.50.7-0.70.8-0.8-0.80.5-0.8-0.8-0.4-0.7-0.7-0.8-0.80.5-0.8-0.8
Glucose0.40.51.20.9-0.80.70.90.80.80.21.11.00.30.80.50.40.80.3
Heart weight0.71.01.70.8-0.81.10.8-1.10.81.30.30.81.20.81.2-1.21.01.3
Left kidney weight0.61.73.51.0-0.91.41.0-1.60.91.70.31.11.90.91.6-1.61.21.7
Right kidney weight0.20.61.90.4-0.30.80.4-1.40.21.1-0.20.41.30.30.9-1.20.51.0
Tail length2.16.326.2-0.50.51.3-0.5-4.7-0.43.6-2.9-0.43.3-0.51.7-5.10.22.8
Length with tail1.03.814.8-1.21.20.3-1.1-3.5-1.22.3-2.9-1.12.2-1.20.6-3.9-0.61.6
Length without tail0.20.50.8-0.70.8-0.8-0.80.5-0.9-0.7-0.5-0.8-0.5-0.8-0.80.4-0.8-0.7
Liver weight, left3.75.98.5-2.92.9-2.5-2.90.4-2.9-1.6-2.9-2.9-1.4-2.9-2.60.2-2.8-2.1
Liver weight, right4.26.911.5-3.23.3-2.6-3.2-0.5-3.4-1.3-3.4-3.2-1.0-3.3-2.5-0.4-3.0-1.9
Parametrial fat weight0.30.62.80.2-0.1-0.30.21.70.1-1.00.90.2-0.90.1-0.51.50.0-0.8
Retroperitoneal fat weight1.24.05.4-2.12.2-2.2-2.11.0-2.2-1.9-1.6-2.1-1.8-2.2-2.31.1-2.2-2.1
Intraocular pressure0.20.20.90.7-0.60.40.40.30.60.01.00.5-0.00.50.30.40.60.2
Extensor digitorum longus weight0.00.20.4-0.20.2-0.4-0.20.6-0.2-0.60.0-0.3-0.5-0.2-0.40.6-0.3-0.5
Soleus weight0.41.11.8-1.31.3-1.1-1.3-0.3-1.3-0.6-1.3-1.3-0.7-1.3-1.0-0.1-1.2-0.8
Tibialis anterior weight0.10.20.7-0.40.5-0.2-0.5-0.7-0.50.3-0.8-0.50.4-0.5-0.1-0.7-0.40.1
Tibia length0.30.81.60.6-0.60.90.6-1.20.61.2-0.00.51.20.61.0-1.30.71.1
Number of licking bursts3.44.06.3-1.81.7-2.2-2.11.9-1.7-2.5-0.8-1.9-2.5-1.5-2.32.1-1.9-2.4
Food consumed during 24 hour testing period2.73.24.41.8-1.82.11.7-1.21.82.01.21.71.91.82.0-1.42.02.1
Times rat made contact with spout0.50.51.0-0.80.8-0.8-1.00.0-0.8-0.6-0.7-1.0-0.7-0.6-0.80.2-0.8-0.7
Mean time between licks in bursts2.53.413.40.1-0.11.30.1-3.50.12.8-1.7-0.02.5-0.01.5-3.70.52.3
Mean num. licks in bursts2.53.04.91.5-1.41.91.5-1.91.42.20.51.52.21.41.9-2.01.62.2
Std. dev. time between licks in bursts0.80.93.1-0.70.70.0-0.8-1.6-0.71.0-1.5-0.61.0-0.80.0-1.8-0.40.6
Water consumed over 24 hours0.60.71.2-0.60.7-0.8-1.10.9-0.7-0.9-0.1-0.7-1.0-0.9-1.10.9-0.7-0.9
Indifference point 0 sec1.93.04.41.6-1.52.01.5-1.71.62.10.91.72.11.62.1-1.71.82.1
Indifference point AUC0.20.20.7-0.20.40.2-0.4-0.4-0.20.6-0.5-0.10.6-0.50.0-0.80.00.4
Indifference point function ln k0.30.51.00.8-1.00.61.0-0.40.70.40.70.60.41.00.7-0.10.70.5
Indifference point function log k0.30.51.00.8-1.00.61.0-0.40.70.40.70.60.41.00.7-0.10.70.5
Delay discounting total patch changes 0 sec1.72.84.01.5-1.51.91.5-1.51.61.91.01.71.91.62.0-1.41.71.9
Delay discounting total patch changes 12 sec0.50.72.10.1-0.30.70.2-1.30.31.2-0.50.41.20.20.8-1.40.41.0
Delay discounting total patch changes 18 sec0.60.71.50.6-0.41.00.5-1.00.71.20.10.71.20.51.0-1.20.81.2
Delay discounting total patch changes 24 sec0.60.72.20.2-0.00.80.2-1.40.21.2-0.40.41.40.10.9-1.50.51.1
Delay discounting total patch changes 6 sec0.61.01.80.9-0.71.10.7-0.91.01.10.61.11.10.81.3-0.91.01.2
Delay discounting time to switch 0 sec2.84.37.5-1.91.6-2.4-1.81.9-1.7-2.6-0.9-1.9-2.7-1.6-2.42.2-2.1-2.6
Delay discounting water rate 0 sec2.23.55.51.6-1.52.11.8-1.81.52.30.81.72.41.72.2-1.91.82.3
Delay discounting water rate 12 sec3.85.78.62.8-2.62.62.9-0.42.71.92.52.81.92.82.6-0.62.82.2
Delay discounting water rate 18 sec3.44.56.02.2-2.12.42.2-1.22.12.31.42.22.32.22.4-1.62.32.4
Delay discounting water rate 24 sec1.01.42.51.4-1.31.21.40.21.30.71.61.50.71.41.10.11.40.9
Delay discounting water rate 6 sec1.62.44.51.7-1.71.62.1-0.41.61.11.61.71.32.01.7-0.31.71.3
Locomotor activity0.61.01.81.0-0.81.11.3-0.41.00.90.81.00.91.21.2-0.51.11.0
Locomotor testing distance1.72.83.91.6-1.41.91.8-1.11.51.90.91.62.01.61.9-1.51.82.0
Locomotor testing rearing0.40.62.00.3-0.20.80.2-0.90.21.2-0.30.51.40.30.7-1.40.51.0
Light reinforcement 10.91.76.3-0.30.3-1.1-0.22.3-0.4-2.00.9-0.2-1.8-0.3-1.22.5-0.6-1.7
Light reinforcement 22.12.76.82.0-1.91.22.01.72.0-0.12.61.9-0.22.01.01.51.70.4
Reaction time number correct0.30.41.50.6-0.80.41.20.10.70.10.70.4-0.20.90.70.30.50.2
Reaction time mean minus median0.20.30.70.2-0.30.40.3-0.80.20.7-0.30.40.80.30.6-0.80.20.6
Reaction time mean minus median AUC0.20.30.70.4-0.40.50.5-0.70.40.7-0.10.50.80.40.7-0.70.40.6
Reaction time num false alarms3.14.36.2-2.22.5-2.3-2.31.1-2.2-2.0-1.5-2.1-2.0-2.3-2.31.3-2.2-2.2
Reaction time num false alarms AUC2.73.75.3-2.02.3-2.1-2.11.3-2.0-2.0-1.3-1.9-1.9-2.1-2.21.3-2.0-2.1
Reaction time trials correct on left0.30.41.50.6-0.80.41.20.10.70.10.70.4-0.20.90.70.30.50.2
Reaction time trials on left0.30.41.60.6-0.80.41.30.20.70.00.70.4-0.31.00.70.40.50.2
Reaction time mean2.43.34.5-2.02.1-2.1-2.10.7-2.1-1.7-1.8-1.9-1.4-2.0-2.00.8-2.1-1.9
Reaction time mean AUC2.73.64.8-2.12.1-2.2-2.10.8-2.1-1.8-1.8-2.0-1.6-2.1-2.10.9-2.2-2.0
Median of all reaction times3.44.65.9-2.32.4-2.4-2.31.2-2.3-2.1-1.8-2.2-1.9-2.3-2.41.2-2.4-2.3
Reaction time omissions0.40.51.2-0.50.4-0.8-0.21.0-0.4-1.1-0.0-0.4-1.0-0.4-0.71.1-0.7-1.0
Reaction time false alarm rate2.73.85.7-2.02.4-2.1-2.41.4-2.0-1.9-1.3-1.8-1.7-2.3-2.31.3-2.0-2.0
Reaction time premature initiation rate0.81.13.30.4-0.20.90.4-1.80.41.5-0.50.31.40.41.1-1.80.61.3
Reaction time premature initiations0.60.91.60.7-0.61.01.0-1.20.81.30.00.61.00.81.2-1.20.81.2
Std. dev. reaction times0.81.12.9-1.31.3-1.0-1.3-0.6-1.3-0.3-1.7-1.2-0.1-1.2-0.8-0.6-1.2-0.6
Reaction time trials completed0.30.41.60.6-0.80.41.30.20.70.00.70.4-0.31.00.70.40.50.2
Reaction time trials AUC0.20.31.20.5-0.70.31.10.00.60.10.50.3-0.20.80.60.20.40.2
Social response proportion0.30.30.7-0.40.6-0.6-0.50.3-0.5-0.7-0.1-0.5-0.8-0.6-0.40.6-0.5-0.6
Social responses0.70.91.6-1.11.3-1.0-1.0-0.0-1.2-0.7-1.0-1.1-0.6-1.2-0.80.1-1.1-0.8
Social time1.21.53.1-0.80.4-1.4-0.81.6-0.8-1.8-0.1-0.8-1.8-0.8-1.41.8-1.1-1.7
Conditioned locomotion0.91.12.1-1.31.4-1.0-1.20.3-1.3-0.7-1.2-1.2-0.5-1.4-1.10.1-1.2-0.9
Cocaine response after cond. corrected0.91.02.1-0.90.6-1.2-1.00.7-0.8-1.4-0.4-1.0-1.4-0.5-1.01.2-1.1-1.3
Cocaine response after cond. not corrected0.30.31.30.0-0.2-0.4-0.00.90.0-0.90.6-0.0-0.90.3-0.31.1-0.2-0.7
Cocaine response before conditioning2.32.94.52.0-1.61.92.10.11.91.41.92.11.51.61.7-0.52.01.6
Saline control response1.11.55.90.0-0.10.80.0-2.3-0.01.8-1.1-0.01.8-0.20.9-2.40.31.5
Condit. Reinf. active minus inactive responses4.55.612.51.5-1.12.61.6-2.81.53.5-0.01.53.51.12.5-3.52.03.2
Condit. Reinf. active-inactive response ratio1.31.32.31.1-0.91.41.1-0.91.01.50.51.01.50.71.2-1.31.21.5
Condit. Reinf. active responses5.37.418.01.6-1.32.81.7-3.71.64.0-0.41.63.91.52.9-4.22.13.6
Condit. Reinf. inactive responses2.63.29.10.7-0.81.60.7-3.00.82.6-0.70.82.51.01.9-3.01.12.3
Condit. Reinf. lever presses11.115.326.73.2-2.84.43.3-3.93.25.11.13.35.23.14.4-4.63.85.0
Condit. Reinf. lever reinforcers received5.98.318.81.8-1.53.11.9-3.81.84.2-0.21.84.11.73.1-4.32.33.8
Pavlov. Cond. lever latency14.519.930.7-4.03.6-5.1-4.13.8-4.0-5.5-1.9-4.1-5.5-4.0-5.14.6-4.5-5.5
Pavlov. Cond. magazine entry latency7.08.011.03.2-3.03.23.3-0.63.22.52.83.32.62.93.0-1.13.32.9
Pavlov. Cond. change in total contacts13.919.428.24.1-3.85.04.2-3.74.15.32.24.15.24.35.1-4.24.55.3
Pavlov. Cond. index score12.416.223.33.9-3.54.74.0-2.83.94.72.24.04.83.64.5-3.74.34.8
Pavlov. Cond. latency score11.815.020.93.8-3.44.54.0-2.43.84.42.44.04.53.54.3-3.24.24.6
Pavlov. Cond. lever contacts14.319.931.23.9-3.65.14.0-4.13.95.61.84.05.63.95.1-4.84.45.5
Pavlov. Cond. magazine entry number9.411.515.0-3.63.4-3.9-3.71.7-3.6-3.5-2.6-3.7-3.4-3.6-3.82.2-3.8-3.7
Pavlov. Cond. intertrial magazine entries0.81.12.7-1.21.5-0.7-1.2-0.9-1.30.2-1.6-1.20.2-1.3-0.6-1.0-1.0-0.2
Pavlov. Cond. lever-magazine prob. diff.11.815.322.33.7-3.34.53.8-2.83.74.72.13.94.73.54.4-3.64.14.7
Pavlov. Cond. response bias16.122.232.64.4-4.15.44.4-3.94.45.72.34.55.64.45.4-4.64.85.7
Conditioned reinforcement - actives0.40.41.00.7-0.80.60.7-0.61.00.50.50.70.50.70.7-0.30.60.6
Conditioned reinforcement - inactives1.01.11.7-1.21.2-1.2-1.3-0.4-0.9-0.8-1.2-1.2-0.9-1.3-1.10.2-1.2-1.0
Conditioned locomotion2.02.44.41.7-1.81.71.7-0.62.11.31.51.71.01.81.7-0.51.71.5
Intermittent access intake day 1-15 change2.72.74.41.9-2.11.62.1-0.72.00.82.01.90.82.11.80.21.81.2
Intermittent access intake escalation2.42.44.01.8-2.01.42.0-0.52.00.72.01.80.72.01.60.31.71.0
Intermittent access intake escalation 20.20.20.70.6-0.60.30.70.20.5-0.20.90.6-0.00.70.20.60.40.0
Intermitt. access day 1 inactive lever presses2.42.63.4-1.81.8-1.9-1.80.2-1.6-1.6-1.4-1.7-1.5-1.8-1.70.8-1.8-1.7
Intermitt. access day 15 inactive lever presses0.30.31.20.5-0.70.50.4-1.10.90.50.30.40.30.60.7-0.40.40.6
Intermitt. access escalation Index0.10.10.6-0.30.2-0.2-0.1-0.8-0.30.0-0.4-0.6-0.1-0.10.0-0.3-0.3-0.1
Intermittent access day 1 total infusions0.30.41.9-0.10.00.5-0.2-0.7-0.11.0-0.70.01.0-0.10.3-1.40.20.8
Intermittent access day 15 total infusions0.60.71.00.8-0.90.90.8-1.00.90.90.40.80.90.90.9-0.70.80.9
Intermittent access terminal intake (last 3 days)0.50.50.80.5-0.70.70.6-0.80.80.90.10.60.90.70.7-0.80.60.8
Intermittent access total infusions0.20.20.70.2-0.40.50.2-0.70.40.7-0.20.20.70.30.3-0.80.30.6
Intermittent access day 1 locomotion0.20.20.4-0.60.4-0.4-0.6-0.4-0.5-0.1-0.7-0.5-0.1-0.6-0.4-0.2-0.5-0.2
Intermittent access day 15 total locomotion0.91.01.61.1-1.21.11.1-0.41.30.71.11.20.71.11.1-0.21.10.9
Intermittent access total locomotion0.30.40.60.5-0.60.70.5-0.60.70.70.30.60.70.60.7-0.60.60.7
Intermittent access standard deviation0.30.30.70.6-0.70.20.7-0.00.8-0.30.90.4-0.40.80.30.70.4-0.1
Cocaine induced anxiety3.54.05.7-2.01.9-2.4-2.20.8-1.5-2.2-1.4-2.1-2.3-2.1-2.31.5-2.3-2.3
Post-drug Anxiety1.71.93.5-1.71.5-1.4-1.8-0.3-1.2-0.7-1.9-1.8-0.9-1.6-1.2-0.3-1.7-1.0
Baseline Anxiety1.11.13.90.4-0.21.00.4-1.1-0.11.7-0.50.31.70.21.1-2.00.61.5
Lifetime Intake0.60.61.20.6-0.80.90.6-0.80.71.10.10.61.10.70.8-1.00.71.0
Incentive Sensitization - Responses0.30.31.3-0.20.20.3-0.1-1.1-0.20.8-0.6-0.10.9-0.10.2-1.10.00.6
Incentive Sensitization - Breakpoint0.20.20.8-0.0-0.00.40.1-0.8-0.00.7-0.30.10.80.10.3-0.90.20.6
Progressive ratio test 1 active lever presses0.00.00.0-0.00.00.1-0.1-0.00.10.1-0.10.10.2-0.1-0.0-0.20.00.1
Progressive ratio test 1 breakpoint0.00.00.1-0.20.10.0-0.1-0.10.10.1-0.2-0.00.2-0.1-0.1-0.3-0.10.1
Progressive ratio test 1 inactive lever presses0.00.00.1-0.20.3-0.1-0.3-0.2-0.30.0-0.2-0.00.2-0.3-0.1-0.2-0.1-0.0
Progressive ratio test 2 active lever presses0.20.20.6-0.40.3-0.0-0.4-0.8-0.30.4-0.7-0.20.5-0.3-0.2-0.7-0.20.2
Progressive ratio test 2 breakpoint0.20.21.0-0.30.30.0-0.4-1.0-0.30.5-0.7-0.20.5-0.3-0.1-0.8-0.20.3
Progressive ratio test 2 inactive lever presses0.00.00.10.1-0.30.20.0-0.30.40.2-0.00.20.30.10.1-0.30.10.2
Total sessions with >9 infusions3.74.15.52.2-2.22.32.1-0.52.32.11.62.22.12.12.1-1.22.32.2
Short access day 1 total inactive lever presses1.01.11.9-1.41.1-1.2-1.3-0.4-0.7-0.9-1.2-1.1-1.0-1.2-1.00.3-1.3-1.0
Short access day 10 total inactive lever presses0.70.81.4-0.90.8-1.0-0.90.7-0.6-1.2-0.3-0.7-1.2-0.8-0.91.0-0.9-1.1
Short access day 1 total infusions1.01.02.40.6-0.81.10.7-1.10.81.5-0.10.71.40.71.0-1.50.81.3
Short access day 10 total infusions0.70.81.70.5-0.70.90.6-1.10.51.3-0.10.61.30.60.9-1.30.71.1
Short access total infusions0.91.01.80.7-0.91.10.8-1.00.91.30.20.81.30.81.1-1.30.91.3
Short access day 1 locomotion1.11.22.21.2-1.31.21.20.31.20.71.31.50.91.21.0-0.01.30.9
Short access day 10 total locomotion0.20.20.50.5-0.60.30.60.10.70.00.70.4-0.10.50.30.30.40.1
Short access total locomotion0.10.10.30.3-0.50.30.40.10.40.10.50.40.10.40.20.20.40.1
Compulsive drug intake0.20.20.9-0.10.2-0.3-0.10.5-0.1-0.70.40.1-0.5-0.1-0.10.9-0.1-0.5
One hour access (0.3 mA shock)0.91.01.31.0-1.11.11.1-0.51.01.00.81.21.11.11.1-0.51.11.0
One hour access (shock baseline)0.60.71.30.6-0.70.90.6-0.90.61.10.10.51.10.70.7-1.10.71.0
Number of responses in last shaping day0.80.81.8-1.11.2-0.7-1.2-0.1-1.1-0.1-1.3-1.1-0.0-1.2-0.9-0.6-1.0-0.4
Context. condit. distance diff. score3.34.06.12.1-1.72.41.8-0.92.02.41.22.12.51.62.1-1.72.32.4
Locomotion velocity, session 10.60.62.10.7-0.60.20.71.40.7-0.61.30.7-0.50.50.01.30.5-0.3
Locomotion distance, session 11.41.83.01.6-1.51.41.60.31.60.91.61.71.01.41.3-0.01.61.1
Locomotion velocity, session 20.50.61.81.0-0.50.90.71.01.00.31.31.10.40.40.40.41.10.5
Locomotion distance, session 21.01.42.71.4-1.11.31.30.71.40.61.71.60.81.21.00.31.50.9
Locomotion velocity, session 30.50.61.40.7-0.60.90.8-0.50.71.00.30.81.20.50.8-0.80.81.0
Locomotion distance, session 31.31.42.21.2-1.51.21.5-0.71.31.10.71.21.11.41.4-0.81.21.2
Stereotopy head waving bouts, day 30.40.51.5-0.91.2-0.6-0.9-0.1-0.9-0.2-0.9-0.7-0.1-0.9-0.6-0.3-0.8-0.4
Stereotopy head waving duration, day 30.20.20.40.5-0.20.60.3-0.00.50.50.60.60.50.30.5-0.20.60.5
Locomotion velocity, session 70.20.30.90.6-0.40.30.30.90.5-0.21.00.6-0.00.30.10.70.5-0.0
Locomotion distance, session 70.30.30.8-0.60.9-0.5-0.70.7-0.6-0.5-0.3-0.4-0.3-0.8-0.70.4-0.5-0.5
Stereotopy head waving bouts, day 72.83.14.51.5-1.62.01.7-1.71.62.10.81.62.11.62.0-1.81.82.1
Stereotopy head waving duration, day 73.03.75.21.8-1.72.21.9-1.61.92.21.01.92.31.92.2-1.72.02.3
Locomotion velocity, session 81.01.12.80.9-0.51.40.6-0.60.91.50.41.01.70.41.0-1.31.21.5
Locomotion distance, session 83.14.66.72.4-1.92.62.2-0.52.32.31.72.52.41.92.3-1.42.52.5
Degree of sensitization distance1.41.43.6-1.31.9-1.0-1.80.3-1.4-0.5-1.3-1.3-0.4-1.7-1.2-0.1-1.1-0.7
Degree of sensitization stereotypy5.76.28.82.2-2.32.82.4-2.32.33.01.12.33.02.32.8-2.42.53.0
Condit. Reinf. active minus inactive responses0.50.63.0-0.40.00.00.0-1.7-0.40.8-1.1-0.40.7-0.10.4-1.4-0.30.5
Condit. Reinf. active-inactive response ratio0.91.04.5-0.70.4-0.1-0.3-2.1-0.70.9-1.6-0.80.8-0.40.3-1.8-0.60.6
Condit. Reinf. active responses0.40.51.5-0.90.6-0.6-0.3-1.1-0.80.0-1.2-0.9-0.1-0.5-0.1-0.7-0.8-0.2
Condit. Reinf. inactive responses0.30.30.6-0.40.4-0.6-0.20.7-0.4-0.8-0.0-0.4-0.7-0.3-0.50.8-0.5-0.7
Incentive salience index mean0.30.41.9-0.60.1-0.3-0.1-1.4-0.50.3-1.1-0.70.2-0.20.1-0.9-0.60.1
Condit. Reinf. lever presses0.00.10.2-0.2-0.1-0.30.2-0.2-0.2-0.2-0.2-0.3-0.40.1-0.00.1-0.3-0.2
Time in familiar zone, hab. session 10.20.20.40.3-0.20.50.6-0.20.40.60.20.40.60.40.5-0.50.50.6
Time in novel zone, hab. session 10.60.50.8-0.80.7-0.9-0.9-0.1-0.9-0.6-0.8-0.9-0.6-0.7-0.70.2-0.9-0.7
Total zone transitions, hab. session 10.50.71.71.0-1.00.81.30.11.00.50.90.90.41.10.9-0.00.90.7
Total locomotion distance, hab. session 10.50.71.4-1.11.1-0.8-0.7-0.6-1.0-0.2-1.2-1.1-0.4-1.0-0.6-0.4-1.0-0.4
Locomotion velocity, hab. session 10.30.51.0-0.91.0-0.7-0.6-0.3-0.9-0.3-0.9-0.9-0.4-0.8-0.5-0.2-0.8-0.4
Time in familiar zone, hab. session 21.31.44.60.3-0.11.10.1-1.90.31.8-0.60.31.80.11.0-2.10.61.5
Time in novel zone, hab. session 20.90.93.30.6-0.6-0.20.61.80.5-1.11.40.6-1.00.6-0.31.80.3-0.8
Total zone transitions, hab. session 23.03.95.02.1-2.12.21.9-1.22.12.11.42.12.02.02.2-1.42.22.2
Total locomotion distance, hab. session 20.30.41.6-0.10.40.3-0.4-1.2-0.20.9-0.7-0.10.8-0.30.3-1.20.10.7
Locomotion velocity, hab. session 20.30.41.4-0.30.50.2-0.5-1.1-0.30.8-0.8-0.30.7-0.50.1-1.2-0.10.6
Novel to familiar place preference ratio1.31.33.0-1.21.4-0.8-1.5-1.1-1.40.0-1.7-1.4-0.1-1.5-0.8-1.0-1.2-0.3
Novelty place preference1.11.22.7-1.11.3-0.7-1.5-1.0-1.30.1-1.6-1.30.0-1.5-0.7-1.0-1.0-0.2
Time in novel zone, NPP test1.11.12.7-1.11.3-0.6-1.4-1.1-1.20.3-1.6-1.20.2-1.4-0.6-1.2-0.9-0.0
Total zone transitions, NPP test1.11.63.21.6-1.61.11.60.71.50.41.81.60.41.41.00.61.40.7
Total locomotion distance, NPP test0.10.10.40.2-0.1-0.10.30.40.1-0.40.40.1-0.40.1-0.00.60.1-0.2
Locomotion velocity, NPP test0.10.20.90.1-0.1-0.30.30.70.1-0.70.50.1-0.70.1-0.21.0-0.1-0.5
Pavlov. Cond. lever latency0.20.31.2-0.10.1-0.4-0.11.0-0.1-0.90.40.1-0.6-0.1-0.51.1-0.2-0.7
Pavlov. Cond. magazine entry latency2.12.84.91.4-1.31.91.5-1.51.42.20.41.42.11.41.9-2.01.62.1
Pavlov. Cond. change in total contacts0.60.62.5-0.20.40.4-0.4-1.2-0.31.1-0.9-0.11.1-0.50.2-1.60.00.8
Pavlov. Cond. index score1.21.63.20.9-0.71.40.9-1.30.91.80.00.91.70.81.3-1.81.11.7
Pavlov. Cond. latency score0.91.23.10.7-0.61.20.7-1.40.71.6-0.20.61.60.61.1-1.70.91.5
Pavlov. Cond. lever contacts0.20.31.00.2-0.10.50.1-0.70.20.9-0.30.10.80.10.4-1.00.30.8
Pavlov. Cond. magazine entry number1.92.44.2-1.31.2-1.8-1.41.4-1.3-2.1-0.4-1.3-2.0-1.3-1.71.9-1.5-2.0
Pavlov. Cond. intertrial magazine entries0.81.01.5-1.00.9-1.2-1.10.4-1.0-1.2-0.6-1.0-1.1-0.8-1.10.8-1.1-1.2
Pavlov. Cond. lever-magazine prob. diff.1.01.32.60.8-0.71.30.9-1.20.81.60.00.81.50.81.2-1.61.01.5
Pavlov. Cond. response bias0.50.61.40.6-0.40.90.6-0.70.51.20.00.61.10.60.9-1.20.71.1
Bone: apparent density0.10.20.3-0.20.2-0.4-0.40.5-0.3-0.50.0-0.3-0.5-0.4-0.60.5-0.3-0.5
Bone surface0.20.41.50.10.00.4-0.0-1.1-0.10.9-0.6-0.11.0-0.20.4-1.20.20.7
Bone volume0.10.20.9-0.10.30.2-0.3-0.8-0.30.6-0.6-0.20.7-0.6-0.0-0.9-0.00.4
Bone: connectivity density0.30.51.60.9-0.90.40.61.00.8-0.31.30.7-0.30.70.20.90.7-0.0
Bone: cortical apparent density2.02.64.6-1.61.7-1.7-2.00.7-1.8-1.4-1.2-1.8-1.5-2.2-2.00.8-1.7-1.5
Bone: cortical area0.10.20.8-0.10.20.2-0.1-0.7-0.20.6-0.6-0.20.6-0.30.1-0.9-0.00.4
Bone: cortical porosity0.10.10.3-0.20.10.10.1-0.5-0.10.3-0.4-0.20.2-0.10.2-0.5-0.10.2
Bone: cortical porosity0.10.10.3-0.20.10.0-0.0-0.6-0.10.3-0.5-0.30.2-0.10.1-0.5-0.10.2
Bone: cortical thickness0.10.20.90.10.1-0.10.01.00.1-0.50.60.1-0.5-0.1-0.30.80.1-0.4
Bone: cortical thickness0.00.00.10.1-0.30.00.2-0.20.10.1-0.1-0.0-0.00.20.2-0.10.00.1
Bone: cortical tissue density1.92.54.5-1.51.6-1.6-1.90.7-1.7-1.4-1.1-1.8-1.5-2.1-1.90.8-1.6-1.5
Bone: elastic displacement0.91.03.70.0-0.1-0.70.11.70.0-1.50.8-0.2-1.60.2-0.71.9-0.3-1.2
Bone: elastic work1.31.77.00.5-0.6-0.60.42.40.4-1.81.60.2-1.90.6-0.72.60.0-1.3
Bone: endosteal estimation0.51.14.5-0.20.00.50.2-2.0-0.31.4-1.4-0.21.6-0.10.7-2.1-0.01.0
Bone: endosteal perimeter0.71.55.10.3-0.40.90.4-2.20.21.8-1.00.21.80.31.1-2.30.41.4
Bone: final force1.21.93.6-1.71.5-1.4-1.5-0.7-1.8-0.6-1.9-1.9-0.6-1.6-1.3-0.4-1.6-0.9
Bone: final moment0.91.42.9-1.41.4-1.1-1.3-0.7-1.5-0.4-1.7-1.6-0.4-1.5-1.1-0.5-1.4-0.7
Bone: marrow area0.41.03.7-0.40.10.30.0-1.9-0.41.2-1.5-0.41.4-0.20.5-1.9-0.20.8
Bone: maximum diameter0.91.75.30.5-0.51.10.7-2.10.41.9-0.70.42.00.31.2-2.30.71.6
Bone: maximum force0.61.12.2-1.21.3-0.9-1.3-0.5-1.3-0.3-1.5-1.3-0.2-1.5-1.0-0.5-1.1-0.5
Bone: maximum moment0.30.61.4-0.81.0-0.5-0.9-0.4-0.90.0-1.1-0.90.1-1.2-0.7-0.6-0.7-0.2
Bone: minimum diameter0.50.92.6-0.81.0-0.1-0.7-1.3-0.90.8-1.6-0.80.9-1.1-0.2-1.6-0.60.4
Bone: periosteal estimation0.30.72.8-0.10.10.40.1-1.5-0.21.1-1.1-0.21.3-0.20.4-1.70.00.8
Bone: periosteal perimeter0.50.92.70.4-0.50.90.5-1.50.31.4-0.40.31.40.30.9-1.70.51.2
Bone: post-yield work0.10.10.80.3-0.10.4-0.0-0.10.10.5-0.00.30.9-0.30.0-0.50.30.5
Bone: stiffness2.53.97.4-2.42.4-1.9-2.3-0.9-2.5-0.8-2.7-2.5-0.7-2.5-1.8-0.6-2.3-1.3
Bone: tissue strength0.90.93.01.0-0.60.50.91.61.0-0.41.71.1-0.30.70.21.30.9-0.0
Bone: trabecular number0.50.72.3-0.10.1-0.7-0.31.4-0.3-1.20.5-0.3-1.2-0.2-0.91.5-0.4-1.1
Bone: trabecular spacing1.21.62.61.6-1.31.41.40.21.50.91.51.60.91.31.3-0.11.51.1
Bone: trabecular thickness1.51.84.0-1.71.7-1.2-1.7-0.8-1.7-0.3-2.0-1.6-0.2-1.8-1.2-0.7-1.5-0.7
Bone: trabecular tissue density4.66.510.9-3.13.1-2.5-3.1-0.7-3.1-1.2-3.3-3.1-1.2-3.3-2.5-0.5-2.9-1.7
Breakpoint value in progressive ratio session0.30.41.50.7-0.60.30.51.20.7-0.20.90.6-0.20.60.00.70.5-0.0
Distance traveled before self-admin0.30.31.3-0.1-0.1-0.4-0.01.1-0.2-0.90.30.0-0.60.0-0.41.1-0.2-0.7
Distance traveled after self-admin0.80.92.21.1-1.30.91.2-0.31.50.51.01.00.41.41.00.11.00.6
Delta time in closed arm before/after self-admin1.81.82.9-1.51.6-1.4-1.60.2-1.7-1.0-1.5-1.5-0.7-1.6-1.40.2-1.5-1.2
Delta time in open arm before/after self-admin1.41.34.60.4-0.41.00.5-2.10.71.6-0.40.41.40.41.2-1.80.71.4
Diff in mean of infusions in LGA sessions2.73.15.1-2.11.7-2.1-2.0-0.1-1.3-1.5-2.0-2.3-1.8-1.8-1.70.5-2.2-1.7
Extinction: sum of active levers before priming0.20.20.8-0.20.3-0.3-0.30.80.1-0.40.1-0.3-0.9-0.3-0.50.5-0.2-0.4
Active lever presses in extinction session 62.72.64.51.7-2.01.71.8-0.92.11.31.51.81.01.81.8-0.51.71.5
Delta distance traveled before/after self-admin1.41.54.80.5-0.61.10.6-2.20.91.8-0.40.41.40.81.3-2.00.71.5
Delta ambulatory time before/after self-admin1.21.33.20.7-0.81.20.8-1.81.11.6-0.00.51.20.91.3-1.70.91.5
Time in closed arm before self-admin3.33.85.12.1-2.22.22.2-0.72.01.81.72.11.82.32.2-1.02.12.0
Time in closed arm after self-admin0.40.40.7-0.60.6-0.7-0.50.7-0.6-0.7-0.3-0.5-0.8-0.5-0.70.6-0.6-0.7
Time in open arm before self-admin4.14.48.2-1.61.5-2.3-1.62.2-1.6-2.8-0.5-1.7-2.9-1.5-2.42.6-1.9-2.7
Time in open arm after self-admin0.20.20.5-0.60.5-0.4-0.5-0.7-0.2-0.1-0.6-0.6-0.1-0.6-0.3-0.2-0.5-0.2
Sum of active levers in priming session hrs 5-60.40.30.60.7-0.80.60.80.10.80.40.70.60.30.70.5-0.00.70.5
Time to tail flick, vehicle, before self-admin0.40.40.90.5-0.90.50.7-0.70.50.50.20.50.90.80.8-0.40.50.5
Time to tail flick, vehicle, after self-admin1.31.42.40.9-1.11.31.1-1.01.61.50.31.01.51.01.1-1.31.11.4
Time to tail flick, test, before self-admin0.80.82.70.2-0.00.80.3-1.40.31.4-0.40.41.50.20.9-1.60.51.2
Time to tail flick, test, after self-admin1.01.14.9-0.40.20.3-0.3-2.2-0.31.3-1.4-0.41.2-0.30.6-2.0-0.21.0
Delta time to tail flick, vehicle, before/after SA0.30.30.80.5-0.40.60.6-0.10.90.60.40.50.40.30.4-0.40.60.6
Delta time to tail flick, test, before/after SA0.10.10.2-0.1-0.1-0.3-0.1-0.0-0.2-0.4-0.1-0.3-0.40.0-0.10.4-0.3-0.4
Ambulatory time before self-admin0.40.41.5-0.20.3-0.6-0.21.2-0.4-1.00.2-0.1-0.8-0.2-0.71.2-0.4-0.9
Ambulatory time after self-admin0.70.72.30.9-0.90.90.9-0.61.50.70.60.80.41.00.9-0.40.90.8
Total heroin consumption1.11.31.81.3-1.21.31.2-0.11.21.10.91.31.31.21.1-0.61.31.1
Area under the delay curve1.01.11.5-1.21.1-1.2-1.2-0.2-0.9-0.9-1.0-1.2-1.1-1.1-1.10.4-1.2-1.1
Delay disc. indifference point, 0s delay0.30.30.60.4-0.20.60.5-0.70.20.70.20.50.80.20.6-0.70.50.7
Delay disc. indifference point, 16s delay1.51.52.7-1.51.2-1.4-1.5-0.9-1.2-0.9-1.5-1.6-1.0-1.3-1.20.1-1.5-1.1
Delay disc. indifference point, 2s delay0.30.31.6-0.40.4-0.0-0.5-1.30.00.5-0.8-0.50.2-0.5-0.0-1.0-0.30.3
Delay disc. indifference point, 24s delay2.12.13.0-1.61.3-1.7-1.6-0.0-1.1-1.5-1.3-1.7-1.6-1.4-1.60.9-1.7-1.6
Delay disc. indifference point, 4s delay0.30.31.8-0.30.40.2-0.3-1.3-0.30.7-0.8-0.30.5-0.30.2-1.1-0.10.5
Delay disc. indifference point, 8s delay0.40.40.6-0.60.5-0.7-0.70.1-0.5-0.7-0.4-0.7-0.7-0.4-0.70.5-0.7-0.7
Delay discount exponential model param1.01.01.41.1-1.01.21.20.10.81.00.91.21.21.01.2-0.61.21.1
Delay discount hyperbolic model param0.80.81.21.0-1.01.01.10.30.70.80.91.11.01.01.0-0.31.00.9
Fecal boli incidents, locomotor time 11.61.75.7-1.20.9-1.5-1.30.6-0.3-1.5-0.7-1.5-2.4-0.9-1.41.1-1.3-1.5
Change in fecal boli incidents, locomotor task0.10.11.10.1-0.10.30.1-0.3-0.40.30.10.31.00.10.3-0.30.20.3
Time >=10cm from walls, locomotor time 10.30.31.00.2-0.10.50.0-1.00.30.8-0.1-0.00.60.10.5-0.90.30.7
Bouts of movement, locomotor time 10.40.41.5-0.70.7-0.5-0.8-1.2-0.5-0.0-1.0-0.8-0.1-0.7-0.2-0.5-0.6-0.1
Total resting periods, locomotor time 10.20.30.5-0.60.5-0.5-0.6-0.7-0.2-0.4-0.6-0.6-0.4-0.5-0.30.1-0.6-0.4
Rest time, locomotor task time 10.20.20.8-0.50.3-0.3-0.5-0.9-0.30.1-0.8-0.50.2-0.3-0.1-0.5-0.4-0.1
Distance moved, locomotor task time 10.10.10.30.4-0.60.20.3-0.10.20.00.30.20.10.30.20.10.20.1
Vertical activity count, locomotor time 10.10.10.2-0.30.2-0.3-0.3-0.2-0.4-0.2-0.4-0.3-0.1-0.1-0.20.0-0.3-0.2
Time >=10cm from walls, locomotor time 21.21.35.0-0.00.20.80.0-2.10.41.7-0.9-0.11.60.01.0-2.20.31.4
Bouts of movement, locomotor time 21.92.05.0-1.71.7-1.1-1.7-1.3-1.5-0.1-2.2-1.9-0.3-1.7-1.1-1.1-1.5-0.5
Total resting periods, locomotor time 22.02.14.4-1.81.7-1.3-1.8-0.9-1.6-0.5-2.1-2.0-0.6-1.7-1.3-0.6-1.6-0.9
Rest time, locomotor task time 21.41.73.3-1.00.8-1.4-0.81.7-0.9-1.8-0.3-0.9-1.7-0.6-1.51.8-1.1-1.7
Distance moved, locomotor task time 22.02.45.01.2-1.21.61.1-2.21.41.90.31.12.11.11.7-1.91.31.9
Vertical activity count, locomotor time 20.40.41.7-0.60.5-0.1-0.4-1.3-0.00.5-1.1-0.40.6-0.40.1-1.1-0.40.3
Weight adjusted by age0.60.71.40.5-0.50.90.4-0.90.61.20.00.61.20.40.8-1.20.71.1
Seeking ratio, delayed vs. immediate footshock0.80.93.0-0.50.4-1.0-0.50.9-0.6-1.60.2-0.6-1.1-0.4-1.01.7-0.7-1.4
Locomotion in novel chamber0.60.72.70.8-0.70.20.71.60.5-0.61.50.9-0.50.70.11.30.6-0.3
Locomotion in novel chamber post-restriction1.01.21.81.3-1.21.21.3-0.21.20.91.21.20.71.31.1-0.41.31.1
Progressive ratio0.40.41.20.7-1.10.50.70.40.80.11.00.80.30.80.60.40.70.3
Food seeking constrained by brief footshock0.91.13.00.6-0.81.00.6-1.50.61.6-0.10.41.30.71.2-1.70.71.4
Seeking ratio, punishment vs. effort0.40.52.1-0.10.40.3-0.1-1.3-0.31.0-0.8-0.30.7-0.20.3-1.5-0.00.7
Run reversals in cocaine runway, females0.20.20.50.00.30.4-0.20.2-0.60.6-0.10.20.7-0.20.3-0.70.20.5
Run reversals in cocaine runway, males0.40.40.7-0.60.5-0.8-0.6-0.2-0.4-0.8-0.4-0.7-0.8-0.6-0.60.6-0.7-0.8
Latency to leave start box in cocaine runway1.01.12.7-1.10.9-1.2-1.00.4-0.3-1.2-0.7-1.1-1.6-0.9-1.30.9-1.2-1.3
Latency to leave start box in cocaine runway, F1.21.32.1-1.41.1-1.3-1.2-0.1-0.6-1.0-1.2-1.5-1.5-1.1-1.30.4-1.4-1.2
Latency to leave start box in cocaine runway, M0.40.41.4-0.20.2-0.5-0.21.00.2-0.80.3-0.2-1.2-0.2-0.61.0-0.3-0.7
Cd content in liver0.60.60.9-0.80.6-0.9-0.60.7-0.8-0.9-0.6-0.9-1.0-0.6-0.90.6-0.9-1.0
Co content in liver1.11.35.3-0.60.70.3-0.6-2.1-0.61.4-1.7-0.61.3-0.70.4-2.3-0.31.0
Cu content in liver0.60.72.8-0.40.20.2-0.6-1.7-0.41.0-1.2-0.50.9-0.40.2-1.6-0.20.7
Fe content in liver0.60.71.7-1.11.3-0.8-0.8-0.2-1.1-0.3-1.2-1.0-0.3-1.2-0.7-0.3-1.0-0.5
K content in liver0.50.51.1-0.60.2-0.9-0.80.3-0.6-0.9-0.3-0.7-1.0-0.6-0.80.8-0.8-0.9
Mg content in liver0.10.10.50.3-0.70.20.2-0.20.40.10.30.3-0.10.30.20.10.20.1
Mn content in liver0.91.13.9-0.1-0.4-0.9-0.11.5-0.1-1.60.6-0.3-1.60.0-0.92.0-0.5-1.4
Na content in liver0.10.10.20.4-0.20.50.2-0.20.40.50.20.40.50.20.4-0.30.40.5
Rb content in liver0.20.31.2-0.1-0.10.30.1-1.1-0.10.7-0.6-0.10.7-0.00.4-1.00.00.5
Se content in liver3.13.86.6-1.71.3-2.3-1.51.8-1.7-2.6-0.8-1.7-2.5-1.5-2.22.2-2.0-2.5
Sr content in liver2.01.93.71.7-1.51.31.70.61.70.51.91.70.41.71.20.51.60.8
Zn content in liver3.33.65.02.0-1.82.21.9-0.82.12.01.52.12.02.02.1-1.22.22.1