Hub : Genes

Rnf121

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020175 0.04 0.03 3.7e-04 0.01 0.02 0.01 0.01 1.7e-02 4.3e-03 8.0e-03 7.1e-03
2 Adipose mRNA stability ENSRNOG00000020175 0.05 0.04 8.5e-05 0.02 0.03 0.03 0.03 1.6e-03 5.4e-04 3.2e-04 7.6e-04
3 Brain gene expression ENSRNOG00000020175 0.09 0.07 4.6e-06 0.05 0.06 0.06 0.06 9.3e-06 2.0e-06 4.3e-06 4.5e-06
4 Brain mRNA stability ENSRNOG00000020175 0.16 0.09 7.5e-12 0.13 0.13 0.12 0.13 2.6e-12 3.8e-12 1.5e-11 5.0e-12
5 IL gene expression ENSRNOG00000020175 0.19 0.13 6.8e-03 0.08 0.06 0.03 0.06 5.0e-03 1.3e-02 8.4e-02 1.7e-02
6 Liver gene expression ENSRNOG00000020175 0.05 0.04 5.1e-04 0.01 0.01 0.01 0.01 2.8e-02 1.5e-02 2.8e-02 2.7e-02
7 Liver mRNA stability ENSRNOG00000020175 0.03 0.02 6.4e-03 0.02 0.01 0.02 0.01 5.2e-03 1.3e-02 4.8e-03 9.5e-03
8 NAcc mRNA stability ENSRNOG00000020175 0.09 0.06 2.0e-05 0.08 0.07 0.07 0.08 1.6e-06 5.2e-06 3.1e-06 1.8e-06
9 OFC mRNA stability ENSRNOG00000020175 0.15 0.11 6.7e-03 0.04 0.07 0.09 0.05 3.1e-02 8.4e-03 3.5e-03 2.2e-02
10 PL gene expression ENSRNOG00000020175 0.06 0.05 1.8e-03 0.04 0.04 0.04 0.04 2.7e-04 5.2e-04 4.5e-04 2.8e-04
11 PL mRNA stability ENSRNOG00000020175 0.2 0.11 3.2e-12 0.16 0.17 0.17 0.16 3.0e-12 1.1e-12 9.6e-13 2.1e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.24.06.52.21.71.8-2.32.51.81.1-2.4-2.10.7-2.6
BMI without tail0.30.61.8-0.7-0.9-0.90.4-0.2-0.9-1.10.3-0.8-1.30.2
Body weight0.31.41.6-1.3-1.3-1.21.2-1.2-1.2-1.11.20.5-1.21.3
Epididymis fat weight0.10.20.70.30.60.50.10.10.50.8-0.10.70.7-0.1
Glucose0.50.71.40.70.60.5-1.21.10.50.2-1.2-1.10.1-1.2
Heart weight0.91.22.6-1.1-1.3-1.20.7-0.9-1.2-1.60.8-0.6-1.60.8
Left kidney weight0.71.93.7-1.4-1.6-1.50.9-1.0-1.6-1.90.9-0.5-1.91.1
Right kidney weight0.51.52.3-1.2-1.4-1.21.1-1.2-1.3-1.51.1-0.0-1.41.3
Tail length7.522.629.4-5.4-5.1-5.24.9-4.9-5.2-4.44.92.1-4.25.0
Length with tail4.014.619.7-4.3-3.9-3.94.0-4.3-3.9-3.34.12.4-2.94.4
Length without tail0.10.10.50.20.30.4-0.1-0.20.40.4-0.10.70.60.2
Liver weight, left1.11.88.6-0.50.30.11.3-1.30.21.31.32.91.51.3
Liver weight, right1.93.111.7-1.2-0.4-0.52.2-2.2-0.40.52.23.40.92.2
Parametrial fat weight1.12.22.71.61.71.6-1.71.51.51.2-1.6-0.71.2-1.6
Retroperitoneal fat weight0.41.33.30.61.31.10.4-0.21.11.60.21.81.80.3
Intraocular pressure0.20.30.70.60.30.5-0.60.50.40.1-0.6-0.80.1-0.6
Extensor digitorum longus weight0.10.30.40.60.60.6-0.40.40.60.7-0.30.10.6-0.5
Soleus weight0.20.61.8-0.4-0.2-0.11.0-1.0-0.10.21.11.40.31.0
Tibialis anterior weight0.20.61.0-0.8-0.7-0.70.9-0.9-0.7-0.51.00.8-0.40.9
Tibia length0.41.01.6-1.1-1.2-1.20.8-0.8-1.2-1.20.8-0.2-1.20.7
Number of licking bursts2.32.85.51.72.12.1-0.90.82.12.2-0.91.12.3-0.8
Food consumed during 24 hour testing period1.21.43.4-1.0-1.4-1.40.2-0.1-1.4-1.70.2-1.4-1.80.1
Times rat made contact with spout0.10.20.60.00.20.20.4-0.40.20.50.40.80.50.4
Mean time between licks in bursts8.311.614.4-3.8-3.7-3.73.5-3.6-3.7-3.33.51.1-3.13.5
Mean num. licks in bursts2.12.54.4-1.7-2.0-2.01.0-0.9-2.0-2.01.0-0.9-2.10.9
Std. dev. time between licks in bursts2.73.24.3-2.0-1.8-1.82.1-2.1-1.8-1.42.11.3-1.22.1
Water consumed over 24 hours0.40.50.80.70.80.9-0.40.40.90.9-0.40.30.9-0.4
Indifference point 0 sec1.32.14.8-1.3-1.8-1.70.7-0.4-1.7-2.00.7-1.1-2.20.7
Indifference point AUC0.50.60.9-0.9-0.9-0.80.7-0.8-0.8-0.90.80.3-0.80.8
Indifference point function ln k0.10.10.50.1-0.0-0.0-0.30.2-0.1-0.2-0.2-0.7-0.1-0.3
Indifference point function log k0.10.10.50.1-0.0-0.0-0.30.2-0.1-0.2-0.2-0.7-0.1-0.3
Delay discounting total patch changes 0 sec0.91.53.9-1.1-1.6-1.40.4-0.2-1.4-1.80.5-1.2-2.00.5
Delay discounting total patch changes 12 sec1.21.62.3-1.4-1.5-1.41.0-0.9-1.4-1.51.20.2-1.41.2
Delay discounting total patch changes 18 sec0.70.91.7-1.0-1.2-1.20.5-0.4-1.1-1.30.5-0.3-1.30.6
Delay discounting total patch changes 24 sec1.51.92.9-1.4-1.7-1.41.2-1.2-1.5-1.71.20.1-1.71.3
Delay discounting total patch changes 6 sec0.60.93.1-0.7-1.2-0.90.5-0.5-0.9-1.50.6-0.6-1.80.5
Delay discounting time to switch 0 sec2.23.37.31.82.22.1-0.81.12.22.7-0.81.32.6-0.9
Delay discounting water rate 0 sec1.62.55.7-1.6-1.9-1.90.6-0.8-1.9-2.40.6-1.1-2.30.8
Delay discounting water rate 12 sec1.11.77.80.1-0.6-0.5-1.21.1-0.5-1.4-1.2-2.8-1.5-1.1
Delay discounting water rate 18 sec1.31.74.1-1.0-1.5-1.50.1-0.0-1.5-1.9-0.0-1.8-2.0-0.0
Delay discounting water rate 24 sec0.50.72.60.50.20.2-0.91.00.2-0.3-1.1-1.6-0.4-1.0
Delay discounting water rate 6 sec0.50.73.10.2-0.2-0.2-1.00.8-0.3-0.7-1.1-1.8-0.8-0.8
Locomotor activity0.20.30.8-0.3-0.5-0.5-0.20.2-0.5-0.7-0.1-0.9-0.9-0.3
Locomotor testing distance0.81.33.0-1.0-1.3-1.40.1-0.1-1.4-1.60.2-1.2-1.70.1
Locomotor testing rearing0.60.91.9-1.2-1.1-1.40.7-0.6-1.3-1.00.70.1-0.90.8
Light reinforcement 12.74.96.52.52.52.5-2.02.12.52.4-2.1-0.52.2-2.1
Light reinforcement 23.64.88.62.11.71.6-2.82.81.61.1-2.8-2.40.7-2.9
Reaction time number correct0.20.20.60.40.30.3-0.60.50.30.1-0.8-0.70.1-0.6
Reaction time mean minus median0.40.50.8-0.8-0.8-0.80.7-0.5-0.8-0.70.70.3-0.90.5
Reaction time mean minus median AUC0.20.30.7-0.6-0.6-0.70.5-0.2-0.7-0.50.50.1-0.80.2
Reaction time num false alarms1.01.43.40.71.21.20.3-0.21.21.80.31.91.80.3
Reaction time num false alarms AUC1.01.43.50.91.31.30.00.11.31.8-0.01.61.9-0.0
Reaction time trials correct on left0.20.20.60.40.30.3-0.60.50.30.1-0.8-0.70.1-0.6
Reaction time trials on left0.20.30.70.50.40.4-0.70.60.40.1-0.8-0.70.2-0.7
Reaction time mean0.71.03.90.30.90.70.6-0.30.81.40.62.01.40.4
Reaction time mean AUC0.91.14.00.41.00.90.5-0.20.91.60.52.01.60.3
Median of all reaction times1.21.64.10.71.31.20.3-0.11.32.00.22.02.00.1
Reaction time omissions0.81.01.61.01.31.1-0.71.11.11.2-0.80.31.3-0.8
Reaction time false alarm rate0.91.33.30.81.31.20.00.11.31.80.11.61.80.0
Reaction time premature initiation rate1.82.43.3-1.8-1.7-1.81.5-1.2-1.8-1.61.50.3-1.71.2
Reaction time premature initiations0.70.91.7-1.1-1.1-1.20.8-0.6-1.2-1.20.7-0.2-1.30.5
Std. dev. reaction times0.71.03.0-0.9-0.5-0.61.4-1.1-0.60.01.41.7-0.01.1
Reaction time trials completed0.20.30.70.50.40.4-0.70.60.40.1-0.8-0.70.2-0.7
Reaction time trials AUC0.10.10.40.30.30.2-0.50.40.20.0-0.6-0.50.1-0.5
Social response proportion0.10.10.30.30.30.50.2-0.40.40.20.20.20.20.3
Social responses0.30.31.2-0.2-0.00.10.8-0.80.00.20.61.10.30.8
Social time1.92.44.51.61.91.7-1.21.21.82.1-1.30.32.1-1.1
Conditioned locomotion0.20.31.5-0.20.10.10.5-0.50.10.50.51.20.60.5
Cocaine response after cond. corrected0.70.81.51.01.11.2-0.40.41.21.2-0.40.61.2-0.4
Cocaine response after cond. not corrected0.91.01.31.11.11.1-1.00.91.10.9-1.0-0.30.9-0.9
Cocaine response before conditioning0.70.93.80.0-0.3-0.4-0.90.9-0.4-0.9-0.9-1.9-1.0-0.9
Saline control response3.54.66.1-2.5-2.4-2.42.2-2.1-2.4-2.02.20.7-2.02.1
Condit. Reinf. active minus inactive responses6.68.112.3-3.2-3.5-3.52.3-2.2-3.5-3.42.3-0.5-3.32.2
Condit. Reinf. active-inactive response ratio0.91.01.7-1.0-1.2-1.20.5-0.5-1.2-1.30.5-0.7-1.30.5
Condit. Reinf. active responses8.712.117.7-3.9-4.2-4.22.9-2.9-4.2-4.02.9-0.3-3.92.8
Condit. Reinf. inactive responses5.46.89.1-2.9-3.0-3.02.4-2.4-3.0-2.82.40.3-2.82.3
Condit. Reinf. lever presses9.713.324.2-3.9-4.5-4.62.2-2.2-4.6-4.82.2-1.9-4.92.1
Condit. Reinf. lever reinforcers received8.912.618.5-4.0-4.3-4.32.9-2.9-4.3-4.22.9-0.4-4.12.8
Pavlov. Cond. lever latency9.412.926.73.64.44.5-1.61.64.55.0-1.62.75.2-1.5
Pavlov. Cond. magazine entry latency2.02.28.8-0.3-1.0-1.1-1.11.1-1.1-1.8-1.1-3.0-2.1-1.2
Pavlov. Cond. change in total contacts8.011.224.3-3.3-4.1-4.11.3-1.3-4.2-4.61.3-2.9-4.91.2
Pavlov. Cond. index score6.38.218.9-2.7-3.5-3.60.8-0.8-3.6-4.10.8-2.9-4.30.6
Pavlov. Cond. latency score5.36.716.1-2.3-3.1-3.20.4-0.4-3.2-3.70.4-3.0-4.00.3
Pavlov. Cond. lever contacts10.214.128.6-3.8-4.6-4.71.9-1.9-4.7-5.21.9-2.6-5.31.7
Pavlov. Cond. magazine entry number3.03.79.31.32.02.10.3-0.42.12.80.33.03.00.4
Pavlov. Cond. intertrial magazine entries1.62.03.5-1.4-1.1-1.11.8-1.8-1.1-0.71.81.5-0.51.9
Pavlov. Cond. lever-magazine prob. diff.6.38.118.5-2.7-3.5-3.50.8-0.8-3.5-4.00.8-2.8-4.30.7
Pavlov. Cond. response bias9.613.228.6-3.6-4.4-4.51.4-1.4-4.5-5.11.4-3.0-5.31.3
Conditioned reinforcement - actives0.10.10.3-0.1-0.1-0.2-0.00.4-0.2-0.1-0.4-0.5-0.3-0.5
Conditioned reinforcement - inactives0.30.41.5-0.10.10.20.9-0.90.20.30.71.20.50.7
Conditioned locomotion0.50.62.6-0.1-0.4-0.5-0.50.8-0.4-0.7-0.6-1.6-1.0-0.9
Intermittent access intake day 1-15 change0.90.93.60.60.10.2-1.21.00.1-0.7-1.1-1.9-0.7-1.1
Intermittent access intake escalation1.01.03.50.70.20.4-1.31.00.3-0.5-1.2-1.9-0.5-1.3
Intermittent access intake escalation 20.50.50.70.70.60.6-0.90.80.60.2-0.8-0.70.4-0.8
Intermitt. access day 1 inactive lever presses0.60.72.40.30.60.80.5-0.80.70.70.51.61.20.9
Intermitt. access day 15 inactive lever presses0.40.41.2-0.4-0.7-0.40.3-0.9-0.5-1.10.3-0.2-0.80.6
Intermitt. access escalation Index0.20.20.4-0.4-0.3-0.30.6-0.7-0.3-0.20.60.5-0.10.6
Intermittent access day 1 total infusions0.91.01.9-1.3-1.1-1.40.8-0.8-1.3-0.90.80.5-0.90.8
Intermittent access day 15 total infusions0.30.30.7-0.5-0.6-0.7-0.0-0.1-0.7-0.8-0.0-0.5-0.8-0.1
Intermittent access terminal intake (last 3 days)0.30.30.7-0.7-0.6-0.80.0-0.1-0.8-0.70.1-0.2-0.60.1
Intermittent access total infusions0.20.20.7-0.7-0.5-0.80.1-0.2-0.8-0.50.20.1-0.40.3
Intermittent access day 1 locomotion0.10.10.4-0.3-0.2-0.20.5-0.4-0.20.00.50.60.00.4
Intermittent access day 15 total locomotion0.30.31.40.1-0.3-0.1-0.60.5-0.2-0.6-0.5-1.2-0.7-0.6
Intermittent access total locomotion0.20.20.4-0.4-0.6-0.60.1-0.0-0.6-0.60.1-0.4-0.7-0.0
Intermittent access standard deviation0.50.50.80.80.70.7-0.90.80.70.4-0.8-0.70.6-0.8
Cocaine induced anxiety1.31.53.30.91.31.50.4-0.41.41.70.31.71.80.3
Post-drug Anxiety1.21.33.6-0.8-0.5-0.41.4-1.7-0.4-0.01.41.90.11.5
Baseline Anxiety2.52.64.1-1.9-1.9-2.01.0-1.5-2.0-2.01.00.2-1.81.5
Lifetime Intake0.40.41.1-0.8-0.7-1.00.1-0.1-1.0-0.80.1-0.2-0.70.2
Incentive Sensitization - Responses0.80.81.3-1.1-0.9-1.10.9-0.7-1.1-0.70.90.5-0.70.8
Incentive Sensitization - Breakpoint0.40.40.8-0.8-0.7-0.90.6-0.4-0.8-0.50.60.2-0.60.4
Progressive ratio test 1 active lever presses0.00.00.0-0.1-0.1-0.20.00.0-0.1-0.1-0.10.10.0-0.1
Progressive ratio test 1 breakpoint0.00.00.1-0.3-0.1-0.30.1-0.1-0.2-0.10.00.20.00.1
Progressive ratio test 1 inactive lever presses0.00.00.0-0.2-0.1-0.1-0.0-0.1-0.1-0.2-0.10.2-0.00.0
Progressive ratio test 2 active lever presses0.30.30.6-0.8-0.5-0.70.7-0.5-0.7-0.20.60.6-0.30.4
Progressive ratio test 2 breakpoint0.40.50.8-0.9-0.7-0.80.8-0.6-0.8-0.40.70.6-0.40.5
Progressive ratio test 2 inactive lever presses0.00.00.1-0.2-0.1-0.30.1-0.1-0.2-0.3-0.10.0-0.2-0.1
Total sessions with >9 infusions1.11.23.3-0.6-0.8-1.2-0.70.9-1.1-1.1-0.8-1.8-1.4-1.0
Short access day 1 total inactive lever presses0.40.41.7-0.10.10.20.8-0.90.20.10.71.30.50.9
Short access day 10 total inactive lever presses0.40.51.00.80.91.0-0.30.11.00.8-0.30.40.9-0.2
Short access day 1 total infusions1.01.12.4-1.3-1.2-1.50.7-0.3-1.4-1.30.5-0.1-1.20.5
Short access day 10 total infusions0.70.71.6-1.1-1.0-1.30.2-0.4-1.2-1.00.3-0.1-1.00.4
Short access total infusions0.70.71.6-1.0-1.0-1.30.3-0.3-1.2-1.20.2-0.3-1.10.3
Short access day 1 locomotion0.60.71.90.40.20.0-1.11.00.0-0.2-1.3-1.4-0.3-1.2
Short access day 10 total locomotion0.30.30.60.50.40.4-0.60.80.40.4-0.6-0.70.3-0.7
Short access total locomotion0.20.20.50.30.30.2-0.60.70.20.4-0.6-0.50.3-0.7
Compulsive drug intake0.40.40.90.90.71.0-0.10.50.90.4-0.4-0.40.2-0.7
One hour access (0.3 mA shock)0.30.30.9-0.2-0.4-0.5-0.30.7-0.4-0.5-0.4-1.0-0.7-0.6
One hour access (shock baseline)0.40.41.2-0.9-0.8-1.10.1-0.1-1.0-0.70.2-0.2-0.70.3
Number of responses in last shaping day0.60.61.8-0.8-0.3-0.61.1-0.7-0.50.10.91.30.20.7
Context. condit. distance diff. score1.51.84.0-1.2-1.6-1.7-0.0-0.2-1.7-2.0-0.0-1.6-2.00.0
Locomotion velocity, session 12.02.13.31.51.31.3-1.71.81.31.1-1.7-1.20.8-1.8
Locomotion distance, session 10.60.72.70.40.10.0-1.01.20.0-0.4-1.0-1.6-0.5-1.1
Locomotion velocity, session 20.80.92.10.80.50.5-1.11.40.50.3-1.1-1.3-0.0-1.4
Locomotion distance, session 20.60.92.70.70.30.3-1.21.40.3-0.2-1.2-1.6-0.3-1.3
Locomotion velocity, session 30.30.30.7-0.6-0.7-0.80.3-0.0-0.8-0.80.3-0.5-0.90.1
Locomotion distance, session 30.30.40.9-0.4-0.6-0.7-0.10.2-0.7-0.9-0.1-0.9-1.0-0.2
Stereotopy head waving bouts, day 30.40.51.1-0.6-0.4-0.31.0-0.9-0.4-0.21.00.9-0.11.0
Stereotopy head waving duration, day 30.10.10.4-0.1-0.3-0.2-0.00.1-0.2-0.5-0.0-0.6-0.6-0.0
Locomotion velocity, session 70.80.81.50.90.80.7-1.11.20.70.5-1.1-0.90.4-1.2
Locomotion distance, session 70.10.10.20.30.40.4-0.10.10.40.5-0.10.40.5-0.1
Stereotopy head waving bouts, day 71.71.94.3-1.4-1.7-1.70.7-0.5-1.7-1.90.7-1.1-2.10.5
Stereotopy head waving duration, day 71.61.94.6-1.3-1.7-1.70.5-0.4-1.7-1.90.5-1.4-2.20.3
Locomotion velocity, session 80.70.91.7-1.0-1.2-1.30.3-0.3-1.2-1.20.3-0.7-1.30.2
Locomotion distance, session 81.11.64.0-0.8-1.2-1.4-0.40.4-1.3-1.8-0.4-2.0-1.9-0.4
Degree of sensitization distance0.40.51.7-0.4-0.1-0.10.9-0.8-0.10.20.91.30.30.9
Degree of sensitization stereotypy3.23.57.7-1.9-2.3-2.40.8-0.7-2.4-2.60.8-1.5-2.80.6
Condit. Reinf. active minus inactive responses2.02.33.3-1.6-1.5-1.41.7-1.8-1.4-1.31.71.0-1.11.8
Condit. Reinf. active-inactive response ratio3.74.06.0-2.1-1.9-1.92.3-2.4-1.9-1.52.31.4-1.32.4
Condit. Reinf. active responses0.91.12.0-1.0-0.8-0.71.4-1.4-0.7-0.61.41.2-0.41.4
Condit. Reinf. inactive responses0.30.40.60.70.70.8-0.40.50.80.7-0.40.10.6-0.5
Incentive salience index mean1.21.42.4-1.2-1.0-1.01.5-1.5-1.0-0.81.51.0-0.71.5
Condit. Reinf. lever presses0.00.00.10.00.00.10.3-0.20.1-0.00.30.20.10.3
Time in familiar zone, hab. session 10.10.10.2-0.3-0.4-0.50.10.1-0.4-0.40.1-0.3-0.5-0.1
Time in novel zone, hab. session 10.20.20.8-0.10.10.20.5-0.60.20.30.50.90.40.6
Total zone transitions, hab. session 10.20.20.80.20.0-0.0-0.60.6-0.0-0.2-0.6-0.9-0.3-0.7
Total locomotion distance, hab. session 10.50.71.5-0.7-0.5-0.41.2-1.1-0.40.01.21.2-0.11.1
Locomotion velocity, hab. session 10.30.40.9-0.5-0.3-0.20.9-0.8-0.20.20.90.90.10.7
Time in familiar zone, hab. session 23.43.54.7-2.1-2.2-2.11.8-1.7-2.1-2.01.80.2-2.01.7
Time in novel zone, hab. session 23.33.34.42.01.91.8-2.12.01.81.5-2.1-1.11.4-2.0
Total zone transitions, hab. session 21.21.54.1-0.9-1.4-1.3-0.0-0.1-1.4-1.9-0.0-1.7-2.0-0.0
Total locomotion distance, hab. session 21.11.51.9-1.3-1.4-1.31.3-1.3-1.3-1.11.30.5-1.11.3
Locomotion velocity, hab. session 21.11.51.9-1.3-1.3-1.21.3-1.4-1.2-1.01.30.6-1.01.3
Novel to familiar place preference ratio2.22.34.8-1.5-1.1-1.11.9-2.1-1.1-0.81.91.7-0.42.2
Novelty place preference2.12.14.3-1.4-1.1-1.11.8-2.0-1.1-0.81.81.5-0.42.1
Time in novel zone, NPP test2.52.65.0-1.6-1.3-1.31.9-2.1-1.3-1.01.91.5-0.62.2
Total zone transitions, NPP test1.01.43.11.00.60.6-1.61.50.60.1-1.6-1.7-0.1-1.7
Total locomotion distance, NPP test0.20.30.40.60.50.6-0.50.50.60.5-0.5-0.40.3-0.6
Locomotion velocity, NPP test0.50.71.01.00.91.0-0.80.80.90.8-0.8-0.40.7-0.9
Pavlov. Cond. lever latency0.81.11.31.11.11.1-1.11.01.11.1-1.1-0.30.9-1.1
Pavlov. Cond. magazine entry latency1.92.54.6-1.7-1.9-2.00.9-0.9-2.0-2.10.9-0.7-2.01.0
Pavlov. Cond. change in total contacts2.12.22.8-1.7-1.6-1.61.6-1.6-1.6-1.41.60.7-1.21.6
Pavlov. Cond. index score1.62.13.3-1.6-1.7-1.81.1-1.0-1.8-1.81.1-0.3-1.71.1
Pavlov. Cond. latency score1.62.13.1-1.6-1.7-1.71.2-1.1-1.7-1.71.2-0.1-1.61.2
Pavlov. Cond. lever contacts0.70.81.0-1.0-1.0-1.00.8-0.8-1.0-1.00.80.1-0.90.9
Pavlov. Cond. magazine entry number1.72.14.01.61.81.8-0.80.81.82.0-0.80.71.9-0.9
Pavlov. Cond. intertrial magazine entries0.40.51.20.60.80.8-0.10.10.91.1-0.10.81.0-0.2
Pavlov. Cond. lever-magazine prob. diff.1.31.72.6-1.4-1.5-1.61.0-0.9-1.6-1.61.0-0.3-1.51.0
Pavlov. Cond. response bias0.70.91.5-1.0-1.1-1.20.6-0.7-1.2-1.20.6-0.2-1.10.7
Bone: apparent density0.10.20.40.50.50.5-0.20.20.50.7-0.20.10.6-0.3
Bone surface0.71.21.5-1.2-1.2-1.21.2-1.2-1.2-1.01.20.4-1.01.1
Bone volume0.50.81.1-1.0-0.9-0.91.1-1.0-0.9-0.71.10.5-0.71.0
Bone: connectivity density0.91.42.31.21.11.0-1.41.41.00.8-1.4-1.10.6-1.5
Bone: cortical apparent density0.50.61.90.40.70.80.3-0.20.81.10.31.41.20.3
Bone: cortical area0.40.60.9-0.9-0.8-0.90.8-0.8-0.9-0.60.80.5-0.60.8
Bone: cortical porosity0.20.20.3-0.6-0.5-0.50.5-0.6-0.5-0.40.50.3-0.30.5
Bone: cortical porosity0.30.30.5-0.6-0.6-0.50.6-0.7-0.5-0.40.60.4-0.40.6
Bone: cortical thickness0.40.70.90.90.90.8-0.90.90.80.7-0.9-0.40.6-1.0
Bone: cortical thickness0.00.00.0-0.1-0.1-0.1-0.0-0.0-0.1-0.1-0.00.1-0.1-0.0
Bone: cortical tissue density0.50.61.80.40.80.80.3-0.20.81.10.31.31.20.3
Bone: elastic displacement2.62.93.71.91.91.9-1.81.61.91.7-1.8-0.61.6-1.7
Bone: elastic work4.76.27.82.82.62.7-2.72.62.62.2-2.7-1.22.0-2.6
Bone: endosteal estimation1.73.64.8-2.2-2.0-2.12.0-2.0-2.1-1.72.01.1-1.52.0
Bone: endosteal perimeter1.93.95.2-2.3-2.2-2.31.9-1.9-2.3-2.01.90.7-1.81.9
Bone: final force0.81.33.8-0.8-0.4-0.41.6-1.5-0.40.31.62.00.41.5
Bone: final moment0.71.22.9-0.9-0.6-0.61.5-1.4-0.50.11.51.70.11.4
Bone: marrow area1.53.24.2-2.0-1.9-1.91.9-1.9-1.9-1.51.91.2-1.31.9
Bone: maximum diameter2.13.85.2-2.2-2.2-2.31.8-1.8-2.3-2.11.80.4-2.01.8
Bone: maximum force0.50.82.2-0.8-0.5-0.51.2-1.2-0.50.01.21.50.11.2
Bone: maximum moment0.30.61.2-0.8-0.5-0.61.0-1.0-0.6-0.21.01.1-0.11.0
Bone: minimum diameter1.42.63.6-1.8-1.5-1.61.9-1.8-1.6-1.11.91.5-1.01.9
Bone: periosteal estimation1.12.22.9-1.7-1.6-1.71.5-1.5-1.6-1.31.50.9-1.21.5
Bone: periosteal perimeter1.11.82.7-1.6-1.5-1.71.1-1.2-1.6-1.51.10.3-1.41.2
Bone: post-yield work0.10.10.2-0.4-0.4-0.50.1-0.2-0.5-0.30.1-0.1-0.30.2
Bone: stiffness1.82.97.7-1.3-0.7-0.72.3-2.2-0.70.12.32.80.32.3
Bone: tissue strength2.52.43.71.61.31.3-1.91.91.30.8-1.9-1.60.6-1.9
Bone: trabecular number1.21.92.91.51.61.5-1.21.21.51.7-1.2-0.21.5-1.3
Bone: trabecular spacing0.50.62.50.3-0.1-0.1-0.90.9-0.1-0.7-0.9-1.6-0.8-0.9
Bone: trabecular thickness1.51.83.8-1.2-0.8-0.81.8-1.8-0.8-0.11.81.90.01.8
Bone: trabecular tissue density2.53.511.0-1.3-0.6-0.62.5-2.3-0.60.42.53.30.62.5
Breakpoint value in progressive ratio session1.01.12.01.01.00.7-1.21.30.80.9-1.4-0.80.9-1.2
Distance traveled before self-admin0.91.01.71.11.11.1-1.00.81.10.8-1.3-0.30.8-1.0
Distance traveled after self-admin0.50.51.30.40.30.1-1.00.90.1-0.2-0.9-1.1-0.4-1.1
Delta time in closed arm before/after self-admin0.50.52.1-0.10.20.20.8-0.70.20.60.71.40.80.8
Delta time in open arm before/after self-admin3.33.14.1-1.8-2.0-1.81.8-1.6-1.9-2.01.90.1-2.01.6
Diff in mean of infusions in LGA sessions1.01.14.7-0.10.30.51.0-1.20.40.91.12.21.01.1
Extinction: sum of active levers before priming0.20.20.40.40.60.4-0.40.30.50.7-0.3-0.00.6-0.5
Active lever presses in extinction session 60.60.62.8-0.1-0.6-0.4-0.40.3-0.5-1.1-0.3-1.7-1.2-0.4
Delta distance traveled before/after self-admin2.32.54.1-1.9-1.8-2.01.3-1.2-2.0-1.61.50.2-1.61.3
Delta ambulatory time before/after self-admin1.41.52.8-1.5-1.5-1.70.8-0.7-1.6-1.41.1-0.2-1.40.8
Time in closed arm before self-admin0.91.03.3-0.5-0.8-1.0-0.40.4-1.0-1.5-0.3-1.8-1.5-0.5
Time in closed arm after self-admin0.20.20.70.50.60.6-0.20.20.60.6-0.30.30.8-0.1
Time in open arm before self-admin4.14.47.72.22.52.6-1.51.02.62.7-1.60.92.8-1.2
Time in open arm after self-admin0.30.30.8-0.4-0.4-0.20.7-0.9-0.3-0.30.70.6-0.20.8
Sum of active levers in priming session hrs 5-60.20.20.70.20.0-0.0-0.80.40.0-0.1-0.6-0.6-0.0-0.5
Time to tail flick, vehicle, before self-admin0.20.20.9-0.4-0.3-0.4-0.3-0.3-0.4-0.9-0.2-0.2-0.60.1
Time to tail flick, vehicle, after self-admin0.91.01.8-1.1-1.2-1.30.2-0.8-1.3-1.30.3-0.6-1.10.7
Time to tail flick, test, before self-admin2.52.43.4-1.6-1.7-1.61.4-1.6-1.7-1.81.40.2-1.81.5
Time to tail flick, test, after self-admin4.84.97.0-2.3-2.2-2.02.6-2.5-2.1-2.02.61.2-2.12.4
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.2-0.3-0.4-0.00.1-0.3-0.2-0.1-0.5-0.2-0.0
Delta time to tail flick, test, before/after SA0.10.10.10.30.30.40.10.00.30.30.10.20.2-0.1
Ambulatory time before self-admin1.01.11.41.11.21.2-0.90.81.21.1-1.1-0.21.1-1.0
Ambulatory time after self-admin0.20.20.7-0.1-0.1-0.3-0.50.5-0.3-0.3-0.4-0.8-0.4-0.6
Total heroin consumption0.30.31.2-0.2-0.4-0.5-0.50.3-0.5-0.8-0.5-1.1-0.7-0.2
Area under the delay curve0.30.31.20.20.40.40.4-0.20.40.80.41.10.80.2
Delay disc. indifference point, 0s delay0.30.30.6-0.5-0.7-0.60.4-0.2-0.6-0.70.4-0.3-0.80.3
Delay disc. indifference point, 16s delay0.60.62.5-0.3-0.00.01.2-0.80.10.51.11.60.50.8
Delay disc. indifference point, 2s delay0.80.91.3-1.1-1.0-1.01.2-1.0-0.9-0.61.10.7-0.61.0
Delay disc. indifference point, 24s delay0.70.72.10.50.80.80.4-0.20.81.20.31.41.20.3
Delay disc. indifference point, 4s delay1.01.11.5-1.2-1.2-1.11.2-1.0-1.1-0.81.20.6-0.81.1
Delay disc. indifference point, 8s delay0.30.30.80.40.60.5-0.10.40.50.9-0.00.50.8-0.3
Delay discount exponential model param0.40.41.0-0.4-0.6-0.6-0.3-0.0-0.6-1.0-0.2-1.0-1.0-0.0
Delay discount hyperbolic model param0.20.30.9-0.1-0.3-0.3-0.40.1-0.4-0.8-0.4-1.0-0.8-0.2
Fecal boli incidents, locomotor time 10.90.92.40.81.21.1-0.30.41.11.5-0.31.01.5-0.4
Change in fecal boli incidents, locomotor task0.10.10.2-0.2-0.4-0.30.4-0.0-0.3-0.00.3-0.1-0.4-0.0
Time >=10cm from walls, locomotor time 10.70.70.9-0.9-1.0-1.00.9-0.7-1.0-0.90.70.0-0.90.8
Bouts of movement, locomotor time 11.01.12.3-0.8-0.9-0.51.5-1.5-0.6-0.81.30.9-0.61.3
Total resting periods, locomotor time 10.20.20.8-0.1-0.20.10.9-0.8-0.0-0.20.60.6-0.00.6
Rest time, locomotor task time 10.20.20.5-0.6-0.4-0.50.7-0.5-0.4-0.10.50.7-0.10.5
Distance moved, locomotor task time 10.00.00.10.20.10.1-0.30.30.10.0-0.3-0.30.0-0.2
Vertical activity count, locomotor time 10.00.00.1-0.0-0.10.00.3-0.20.00.00.10.30.10.3
Time >=10cm from walls, locomotor time 23.74.05.1-2.3-2.3-2.22.0-1.9-2.2-2.02.00.7-2.11.7
Bouts of movement, locomotor time 22.22.44.4-1.5-1.1-1.12.1-2.0-1.1-0.42.02.1-0.11.9
Total resting periods, locomotor time 21.41.44.1-1.0-0.5-0.61.7-1.5-0.60.11.62.00.31.5
Rest time, locomotor task time 22.22.54.41.61.91.8-1.21.31.82.0-1.20.52.1-1.2
Distance moved, locomotor task time 21.92.24.3-1.6-1.9-1.81.0-1.0-1.8-1.91.0-0.6-2.10.9
Vertical activity count, locomotor time 20.91.01.5-1.1-1.1-1.01.2-0.9-1.0-0.71.10.9-0.81.1
Weight adjusted by age1.01.22.4-1.1-1.3-1.20.7-1.0-1.3-1.50.7-0.3-1.30.8
Seeking ratio, delayed vs. immediate footshock1.92.13.11.71.71.8-1.31.01.71.7-1.4-0.11.5-1.4
Locomotion in novel chamber1.72.13.61.51.31.3-1.91.61.30.9-1.9-1.20.8-1.7
Locomotion in novel chamber post-restriction0.30.31.4-0.0-0.3-0.3-0.40.7-0.3-0.4-0.4-1.2-0.6-0.7
Progressive ratio0.20.30.80.50.30.4-0.40.60.4-0.1-0.4-0.9-0.4-0.8
Food seeking constrained by brief footshock2.12.53.7-1.7-1.9-1.71.4-1.6-1.8-1.71.60.0-1.81.3
Seeking ratio, punishment vs. effort1.21.52.2-1.5-1.4-1.51.2-1.2-1.4-0.81.10.7-0.71.4
Run reversals in cocaine runway, females0.30.30.5-0.6-0.6-0.70.3-0.5-0.7-0.70.30.0-0.70.4
Run reversals in cocaine runway, males0.20.20.40.50.50.70.10.20.60.60.10.40.4-0.2
Latency to leave start box in cocaine runway0.70.72.00.71.10.80.00.60.91.40.00.91.3-0.3
Latency to leave start box in cocaine runway, F0.40.51.70.10.50.30.6-0.20.41.00.61.31.00.5
Latency to leave start box in cocaine runway, M1.11.01.61.01.31.0-0.71.21.11.3-0.9-0.11.1-1.1
Cd content in liver0.40.41.00.50.80.6-0.40.40.70.9-0.40.71.0-0.3
Co content in liver4.35.16.4-2.5-2.4-2.32.5-2.4-2.3-1.92.51.3-1.82.5
Cu content in liver2.12.63.3-1.8-1.7-1.71.8-1.8-1.7-1.31.81.0-1.21.8
Fe content in liver0.50.61.4-0.6-0.4-0.41.0-1.0-0.4-0.11.01.20.01.1
K content in liver0.30.30.60.60.70.7-0.10.10.70.7-0.10.40.8-0.1
Mg content in liver0.00.00.10.10.00.1-0.10.10.1-0.1-0.1-0.3-0.1-0.2
Mn content in liver2.83.24.22.02.02.0-1.71.72.02.0-1.7-0.31.9-1.7
Na content in liver0.10.10.2-0.2-0.4-0.30.0-0.1-0.3-0.40.1-0.3-0.50.0
Rb content in liver0.70.91.1-1.1-1.0-1.01.0-0.9-1.0-0.90.90.4-0.91.0
Se content in liver2.83.47.21.92.32.2-1.10.92.22.6-1.01.12.7-1.0
Sr content in liver1.31.23.60.90.50.5-1.41.40.50.0-1.4-1.9-0.1-1.5
Zn content in liver1.11.23.0-0.7-1.2-1.2-0.20.2-1.2-1.6-0.3-1.7-1.7-0.2