Hub : Genes

Mtus2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000032410 0.04 0.03 4.5e-05 0.04 0.03 0.02 0.03 7.3e-05 4.5e-04 2.1e-03 3.2e-04
2 BLA mRNA stability ENSRNOG00000032410 0.36 0.16 5.9e-13 0.22 0.18 0.2 0.2 3.0e-12 6.8e-10 6.6e-11 4.5e-11
3 Brain gene expression ENSRNOG00000032410 0.28 0.1 6.6e-13 0.15 0.14 0.14 0.15 8.2e-14 9.3e-13 3.2e-13 6.2e-14
4 Brain mRNA stability ENSRNOG00000032410 0.06 0.04 2.9e-05 0.06 0.05 0.07 0.06 2.3e-06 2.2e-05 3.6e-07 5.3e-06
5 IL mRNA stability ENSRNOG00000032410 0.18 0.1 4.1e-04 0.07 0.15 0.11 0.06 7.5e-03 1.7e-04 1.3e-03 1.4e-02
6 LHb mRNA stability ENSRNOG00000032410 0.19 0.12 1.8e-03 0.07 0.1 0.07 0.06 9.5e-03 2.8e-03 1.1e-02 1.8e-02
7 NAcc alternative TSS ENSRNOT00000085869 0.07 0.05 4.7e-03 0 0.02 0.01 0.01 1.7e-01 5.8e-03 1.1e-01 8.9e-02
8 NAcc alternative TSS ENSRNOT00000104730 0.07 0.05 3.2e-03 0 0.03 0.01 0.01 1.5e-01 5.2e-03 9.9e-02 9.4e-02
9 NAcc isoform ratio ENSRNOT00000085869 0.08 0.05 1.2e-03 -0 0.03 0.01 0.01 4.8e-01 4.0e-03 4.6e-02 6.2e-02
10 OFC mRNA stability ENSRNOG00000032410 0.32 0.12 1.3e-08 0.32 0.33 0.23 0.33 1.9e-08 1.0e-08 3.7e-06 1.2e-08
11 PL gene expression ENSRNOG00000032410 0.06 0.04 5.6e-05 0.03 0.04 0.01 0.03 1.2e-03 7.1e-04 6.8e-02 3.9e-03
12 PL mRNA stability ENSRNOG00000032410 0.37 0.11 0.0e+00 0.39 0.41 0.4 0.41 3.5e-31 7.3e-33 5.0e-32 7.6e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.61.93.1-1.31.41.50.61.21.31.7-1.71.71.71.00.9
BMI without tail0.61.23.01.5-0.9-0.9-1.1-1.4-1.00.1-0.10.5-0.8-1.7-1.5
Body weight1.46.19.72.8-2.5-2.6-3.1-2.8-2.6-1.71.7-1.2-2.1-2.8-2.9
Epididymis fat weight0.61.53.1-0.31.31.3-0.10.91.21.6-1.71.81.60.60.8
Glucose0.91.42.20.4-1.3-0.9-1.1-1.0-1.4-1.51.4-1.5-1.0-0.7-1.5
Heart weight0.60.81.50.3-1.2-0.7-0.9-0.9-0.9-0.60.7-0.7-1.2-1.1-1.2
Left kidney weight1.95.48.72.9-2.1-2.7-2.9-2.3-2.5-2.22.1-1.8-1.8-1.9-2.4
Right kidney weight1.95.311.13.3-2.2-3.0-2.9-2.5-2.4-1.51.4-0.9-1.5-2.4-2.3
Tail length6.620.026.15.1-4.6-4.7-4.4-4.8-4.7-3.84.0-3.3-4.6-4.6-4.7
Length with tail7.828.532.95.6-5.6-5.7-5.1-5.5-5.7-5.15.2-4.6-5.4-5.0-5.4
Length without tail1.53.34.91.7-2.0-2.2-1.8-1.8-2.0-1.91.9-1.7-1.6-1.6-1.7
Liver weight, left0.20.32.11.50.3-0.3-0.1-0.10.20.5-0.50.70.5-0.10.5
Liver weight, right1.62.65.92.4-1.3-2.0-1.2-2.1-1.8-0.90.9-0.4-1.4-2.1-1.7
Parametrial fat weight0.10.10.70.8-0.1-0.1-0.8-0.00.10.2-0.20.30.3-0.00.0
Retroperitoneal fat weight0.10.31.10.60.2-0.1-0.4-0.40.00.7-0.71.00.4-0.5-0.0
Intraocular pressure1.11.52.9-0.70.91.40.61.11.31.3-1.41.51.71.11.4
Extensor digitorum longus weight0.20.72.31.5-0.6-0.7-1.5-0.8-0.7-0.50.5-0.2-0.3-0.7-0.5
Soleus weight0.20.72.91.7-0.2-0.2-0.8-0.7-0.10.8-0.71.2-0.2-1.1-0.2
Tibialis anterior weight0.10.31.01.0-0.3-0.6-0.6-0.6-0.30.1-0.10.3-0.1-0.7-0.4
Tibia length0.41.22.60.9-1.1-1.0-0.9-1.5-1.2-0.50.6-0.3-1.2-1.6-1.4
Number of licking bursts0.81.01.81.4-0.9-1.1-0.8-1.0-1.0-0.90.9-0.8-1.0-0.9-0.9
Food consumed during 24 hour testing period0.81.01.60.8-1.0-1.3-0.9-0.8-1.0-1.21.2-1.2-1.0-0.6-0.8
Times rat made contact with spout1.01.11.41.1-1.2-1.1-1.1-1.1-1.0-0.90.9-0.8-1.1-1.1-1.1
Mean time between licks in bursts1.82.43.8-1.51.91.81.91.41.71.6-1.51.41.11.21.6
Mean num. licks in bursts0.20.30.9-1.00.40.60.40.60.60.4-0.40.20.40.50.5
Std. dev. time between licks in bursts0.91.03.00.2-0.9-0.5-1.0-0.4-0.9-1.61.5-1.7-0.9-0.0-0.8
Water consumed over 24 hours1.51.72.41.3-1.5-1.3-1.5-1.4-1.3-0.91.0-0.8-1.4-1.5-1.6
Indifference point 0 sec0.40.61.60.8-0.8-1.3-0.7-0.8-0.8-0.60.6-0.5-0.6-0.7-0.8
Indifference point AUC0.81.02.10.5-1.0-0.7-1.0-0.6-0.9-1.41.4-1.5-0.8-0.3-0.8
Indifference point function ln k0.20.31.20.3-0.6-0.90.1-0.8-0.40.2-0.10.3-0.7-1.1-0.6
Indifference point function log k0.20.31.20.3-0.6-0.90.1-0.8-0.40.2-0.10.3-0.7-1.1-0.6
Delay discounting total patch changes 0 sec0.40.71.80.9-0.8-1.3-0.7-0.8-0.9-0.70.7-0.6-0.7-0.8-0.8
Delay discounting total patch changes 12 sec0.70.91.30.7-1.0-1.1-0.8-1.0-1.1-1.01.0-0.9-0.9-0.8-1.1
Delay discounting total patch changes 18 sec0.50.71.2-0.70.90.40.51.10.90.6-0.70.51.11.11.0
Delay discounting total patch changes 24 sec1.21.51.91.1-1.2-1.3-1.4-1.1-1.4-1.31.3-1.3-1.1-0.9-1.3
Delay discounting total patch changes 6 sec1.52.33.71.4-1.7-1.9-1.6-1.6-1.6-1.11.1-0.9-1.4-1.6-1.6
Delay discounting time to switch 0 sec1.11.62.4-0.71.41.31.11.11.31.5-1.51.51.40.91.3
Delay discounting water rate 0 sec0.00.10.2-0.2-0.2-0.20.0-0.2-0.2-0.20.2-0.3-0.5-0.3-0.4
Delay discounting water rate 12 sec0.30.41.40.6-0.4-1.0-0.3-0.8-0.40.5-0.40.6-0.5-1.2-0.5
Delay discounting water rate 18 sec1.62.12.71.6-1.3-1.5-1.0-1.6-1.6-1.41.4-1.2-1.7-1.5-1.5
Delay discounting water rate 24 sec0.40.62.1-0.81.00.41.40.30.61.0-0.90.90.3-0.00.4
Delay discounting water rate 6 sec0.20.31.30.20.6-0.11.10.10.50.8-0.60.70.0-0.10.5
Locomotor activity1.01.63.11.3-1.5-1.2-1.1-1.6-1.4-0.50.6-0.3-1.3-1.8-1.7
Locomotor testing distance0.10.20.2-0.40.30.30.40.50.40.4-0.40.40.30.40.3
Locomotor testing rearing0.71.11.6-0.91.10.91.31.01.11.2-1.21.11.00.81.1
Light reinforcement 10.71.33.70.9-1.0-0.6-1.0-0.4-1.0-1.81.7-1.9-0.80.2-0.6
Light reinforcement 20.30.41.20.20.1-0.0-0.40.4-0.2-1.00.9-1.10.31.00.3
Reaction time number correct0.10.20.60.2-0.3-0.70.2-0.5-0.4-0.30.3-0.3-0.4-0.5-0.3
Reaction time mean minus median0.40.62.81.7-0.7-0.4-0.8-0.8-0.5-0.30.3-0.1-0.7-0.9-0.4
Reaction time mean minus median AUC0.30.41.81.4-0.5-0.7-0.3-0.7-0.4-0.20.2-0.0-0.6-0.8-0.2
Reaction time num false alarms1.31.82.91.6-1.3-1.7-0.8-1.3-1.4-1.31.4-1.3-1.4-1.1-1.3
Reaction time num false alarms AUC1.11.52.91.7-1.1-1.5-0.9-1.2-1.3-1.21.2-1.1-1.1-1.0-1.1
Reaction time trials correct on left0.10.20.60.2-0.3-0.70.2-0.5-0.4-0.30.3-0.3-0.4-0.5-0.3
Reaction time trials on left0.10.10.50.2-0.3-0.70.2-0.4-0.4-0.30.3-0.2-0.4-0.5-0.3
Reaction time mean1.42.02.7-1.31.61.61.51.41.61.4-1.41.21.21.21.5
Reaction time mean AUC2.12.74.1-1.51.82.01.61.71.91.6-1.61.41.41.51.8
Median of all reaction times3.14.25.2-2.22.32.32.22.22.21.9-1.91.61.81.92.1
Reaction time omissions0.50.60.9-0.70.51.00.50.70.90.9-0.90.90.70.50.9
Reaction time false alarm rate0.71.02.11.5-1.0-1.1-0.9-0.9-1.0-1.01.0-0.9-0.9-0.8-0.9
Reaction time premature initiation rate2.93.94.81.7-2.1-1.8-2.1-1.9-2.2-2.12.1-2.0-2.0-1.7-2.2
Reaction time premature initiations2.53.54.41.6-2.0-1.8-1.6-1.9-2.1-1.91.9-1.8-2.0-1.8-2.1
Std. dev. reaction times0.10.20.60.80.20.2-0.1-0.10.20.5-0.50.60.0-0.30.3
Reaction time trials completed0.10.10.50.2-0.3-0.70.2-0.4-0.4-0.30.3-0.2-0.4-0.5-0.3
Reaction time trials AUC0.10.10.50.1-0.2-0.70.2-0.4-0.4-0.20.2-0.1-0.3-0.5-0.3
Social response proportion0.10.10.2-0.4-0.30.2-0.3-0.3-0.10.10.00.1-0.4-0.4-0.4
Social responses3.34.25.92.0-2.3-2.1-1.4-2.4-2.2-1.71.8-1.5-2.4-2.4-2.2
Social time0.20.30.7-0.50.20.70.50.20.40.8-0.70.80.50.10.3
Conditioned locomotion1.01.22.5-1.51.11.61.11.21.20.9-0.90.70.81.00.9
Cocaine response after cond. corrected0.91.01.5-0.91.00.90.91.01.11.2-1.21.21.10.70.8
Cocaine response after cond. not corrected0.60.71.2-0.60.80.90.60.80.91.1-1.01.10.80.50.7
Cocaine response before conditioning1.51.82.41.5-1.3-1.0-1.2-1.5-1.5-1.31.4-1.2-1.6-1.4-1.4
Saline control response2.12.83.91.3-1.7-2.0-1.1-1.7-1.9-1.71.7-1.6-1.9-1.6-1.8
Condit. Reinf. active minus inactive responses1.51.92.91.2-1.4-1.2-1.0-1.5-1.5-1.31.3-1.2-1.6-1.4-1.7
Condit. Reinf. active-inactive response ratio2.52.63.31.7-1.7-1.6-1.3-1.7-1.8-1.51.6-1.4-1.7-1.6-1.8
Condit. Reinf. active responses2.63.75.21.4-2.0-1.7-1.3-2.0-2.2-2.02.0-1.9-2.2-1.8-2.3
Condit. Reinf. inactive responses1.11.42.00.5-1.2-1.2-0.5-1.3-1.4-1.21.2-1.2-1.4-1.2-1.4
Condit. Reinf. lever presses1.01.32.81.2-1.1-1.0-1.0-1.5-1.3-0.40.5-0.2-1.1-1.7-1.6
Condit. Reinf. lever reinforcers received2.84.05.91.5-2.1-1.8-1.4-2.1-2.3-1.92.0-1.8-2.2-2.0-2.4
Pavlov. Cond. lever latency0.50.71.7-0.41.00.21.00.90.90.6-0.70.60.90.91.3
Pavlov. Cond. magazine entry latency0.60.62.2-0.30.60.9-0.10.20.71.3-1.31.50.5-0.30.3
Pavlov. Cond. change in total contacts0.40.61.90.4-0.7-0.4-0.8-1.0-0.70.2-0.10.4-0.7-1.4-1.1
Pavlov. Cond. index score0.40.61.50.4-0.8-0.1-1.0-1.0-0.70.00.00.2-0.7-1.2-1.2
Pavlov. Cond. latency score0.30.41.10.4-0.7-0.2-0.9-0.8-0.60.00.00.2-0.6-1.1-1.0
Pavlov. Cond. lever contacts0.20.30.90.0-0.70.1-0.6-0.6-0.6-0.40.4-0.3-0.5-0.6-1.0
Pavlov. Cond. magazine entry number0.30.41.70.1-0.3-0.50.30.1-0.3-1.11.1-1.3-0.40.50.0
Pavlov. Cond. intertrial magazine entries2.43.15.90.5-1.7-1.5-0.6-1.4-1.9-2.32.3-2.4-2.0-1.1-1.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.30.5-0.8-0.2-1.1-0.9-0.7-0.10.20.1-0.6-1.1-1.1
Pavlov. Cond. response bias0.20.20.70.0-0.40.3-0.5-0.6-0.40.2-0.20.3-0.4-0.8-0.8
Conditioned reinforcement - actives1.21.21.91.3-1.2-1.4-0.8-1.3-1.2-0.80.8-0.6-1.0-1.3-1.1
Conditioned reinforcement - inactives0.40.51.20.1-1.1-1.0-0.6-0.7-0.8-0.40.4-0.4-0.6-0.8-1.0
Conditioned locomotion3.64.36.52.3-2.2-2.5-1.7-2.3-2.3-1.71.8-1.5-2.1-2.2-2.0
Intermittent access intake day 1-15 change0.70.72.1-0.80.31.5-0.61.00.90.5-0.60.40.91.10.6
Intermittent access intake escalation0.60.62.2-0.90.21.5-0.41.00.90.5-0.50.30.71.00.6
Intermittent access intake escalation 22.42.45.7-2.01.02.40.22.01.81.1-1.10.71.41.91.4
Intermitt. access day 1 inactive lever presses0.40.51.00.4-0.5-1.0-0.0-0.6-0.8-0.80.8-0.8-0.7-0.5-0.7
Intermitt. access day 15 inactive lever presses1.51.72.60.9-1.3-1.5-1.3-1.5-1.5-1.11.0-0.9-1.1-1.4-1.6
Intermitt. access escalation Index1.61.42.3-0.91.01.11.21.31.41.2-1.21.11.31.21.5
Intermittent access day 1 total infusions0.50.51.40.5-0.5-1.20.5-0.9-0.60.1-0.00.2-0.7-1.2-0.9
Intermittent access day 15 total infusions0.10.10.3-0.1-0.5-0.00.0-0.20.00.5-0.50.5-0.1-0.5-0.4
Intermittent access terminal intake (last 3 days)0.10.10.5-0.3-0.10.00.10.00.20.6-0.60.70.2-0.2-0.1
Intermittent access total infusions0.30.31.00.2-0.6-0.7-0.2-0.7-0.50.2-0.20.3-0.4-1.0-0.8
Intermittent access day 1 locomotion0.30.31.10.0-0.3-0.80.3-0.8-0.50.1-0.00.2-0.6-1.0-0.8
Intermittent access day 15 total locomotion1.82.03.71.0-1.7-1.3-1.6-1.6-1.6-0.90.9-0.6-1.2-1.7-1.9
Intermittent access total locomotion1.41.63.10.8-1.3-1.4-1.6-1.4-1.4-0.80.8-0.6-1.1-1.5-1.8
Intermittent access standard deviation0.10.10.4-0.50.0-0.0-0.6-0.00.00.3-0.30.30.2-0.1-0.1
Cocaine induced anxiety0.20.20.6-0.1-0.3-0.20.70.20.40.7-0.70.70.3-0.10.1
Post-drug Anxiety0.60.71.1-0.40.20.41.00.80.91.1-1.11.00.90.60.8
Baseline Anxiety0.20.20.7-0.40.40.7-0.50.60.3-0.20.1-0.30.50.90.5
Lifetime Intake0.30.41.10.1-0.7-0.8-0.0-0.8-0.50.1-0.10.3-0.6-1.1-0.9
Incentive Sensitization - Responses0.20.20.8-0.5-0.5-0.1-0.7-0.4-0.30.4-0.30.4-0.1-0.6-0.9
Incentive Sensitization - Breakpoint0.20.20.7-0.4-0.4-0.0-0.7-0.3-0.20.3-0.30.4-0.1-0.6-0.8
Progressive ratio test 1 active lever presses2.32.46.41.3-1.2-1.8-0.3-2.2-1.7-0.40.5-0.1-1.7-2.5-2.1
Progressive ratio test 1 breakpoint1.81.95.11.1-1.0-1.60.0-1.9-1.5-0.40.5-0.1-1.6-2.3-1.9
Progressive ratio test 1 inactive lever presses1.61.73.51.0-0.9-1.4-0.4-1.8-1.5-0.91.0-0.7-1.6-1.9-1.8
Progressive ratio test 2 active lever presses0.50.51.8-0.0-0.6-0.5-0.5-0.9-0.60.4-0.30.5-0.6-1.3-1.4
Progressive ratio test 2 breakpoint0.50.61.90.1-0.7-0.5-0.6-1.0-0.70.1-0.10.3-0.7-1.3-1.4
Progressive ratio test 2 inactive lever presses1.41.64.10.6-1.5-1.3-1.0-1.6-1.3-0.20.3-0.0-1.3-2.0-2.0
Total sessions with >9 infusions1.01.02.50.7-1.2-1.0-1.0-1.3-1.0-0.20.3-0.1-1.1-1.6-1.4
Short access day 1 total inactive lever presses5.15.77.31.6-2.6-2.4-2.6-2.4-2.6-2.22.3-2.1-2.6-2.3-2.7
Short access day 10 total inactive lever presses0.40.40.80.4-0.3-0.8-0.4-0.5-0.6-0.80.9-0.9-0.9-0.4-0.5
Short access day 1 total infusions0.10.10.5-0.00.2-0.10.7-0.00.20.5-0.40.5-0.1-0.30.1
Short access day 10 total infusions1.71.93.21.1-1.6-1.7-0.9-1.7-1.5-0.80.9-0.7-1.5-1.8-1.6
Short access total infusions0.50.51.50.1-0.8-1.0-0.2-1.0-0.7-0.10.2-0.0-0.8-1.2-1.1
Short access day 1 locomotion0.20.20.50.3-0.5-0.6-0.5-0.6-0.5-0.30.3-0.2-0.5-0.6-0.7
Short access day 10 total locomotion0.40.51.10.1-0.4-0.4-1.0-0.6-0.7-0.60.7-0.7-0.9-0.7-0.9
Short access total locomotion0.80.91.60.5-0.6-1.0-0.7-1.2-1.1-0.70.7-0.6-1.2-1.3-1.1
Compulsive drug intake0.30.31.2-1.1-0.00.90.10.50.2-0.30.2-0.40.30.70.2
One hour access (0.3 mA shock)0.60.71.8-0.2-1.1-0.3-0.4-0.7-0.9-0.80.8-0.8-0.9-0.7-1.3
One hour access (shock baseline)0.50.61.40.8-0.7-1.0-0.1-1.0-0.8-0.20.3-0.1-0.8-1.2-1.1
Number of responses in last shaping day0.40.40.7-0.00.70.30.80.40.70.8-0.80.90.50.30.8
Context. condit. distance diff. score0.50.71.21.1-0.7-0.4-0.9-0.7-0.7-1.01.0-0.9-0.9-0.5-0.5
Locomotion velocity, session 12.22.43.31.2-1.6-1.2-1.5-1.4-1.6-1.81.8-1.8-1.6-1.1-1.6
Locomotion distance, session 10.20.20.8-0.2-0.4-0.1-0.50.0-0.3-0.80.7-0.9-0.20.2-0.3
Locomotion velocity, session 20.60.71.50.3-1.0-0.3-1.1-0.5-0.8-1.11.1-1.2-0.8-0.3-1.0
Locomotion distance, session 20.91.42.00.7-1.4-0.8-1.3-0.9-1.2-1.41.4-1.4-1.0-0.7-1.4
Locomotion velocity, session 31.11.21.91.2-1.1-1.3-1.1-0.9-1.1-1.41.3-1.3-0.9-0.6-0.8
Locomotion distance, session 30.90.92.61.0-1.0-1.6-0.7-1.0-1.0-0.70.7-0.6-0.9-1.1-1.0
Stereotopy head waving bouts, day 30.00.00.10.2-0.00.4-0.1-0.10.1-0.00.1-0.1-0.4-0.10.1
Stereotopy head waving duration, day 30.10.20.70.10.40.80.00.30.50.3-0.20.20.20.40.6
Locomotion velocity, session 70.70.71.91.0-0.9-0.1-1.4-1.0-0.8-0.70.7-0.5-0.8-0.9-0.9
Locomotion distance, session 70.10.10.40.4-0.20.6-0.6-0.1-0.1-0.40.4-0.4-0.3-0.0-0.2
Stereotopy head waving bouts, day 71.41.62.91.4-1.3-1.7-1.2-1.5-1.3-0.80.9-0.6-1.3-1.5-1.3
Stereotopy head waving duration, day 71.11.42.51.1-1.2-1.6-0.9-1.4-1.3-0.80.9-0.7-1.2-1.4-1.3
Locomotion velocity, session 82.93.55.31.3-2.0-1.4-1.6-1.7-2.0-2.32.3-2.3-2.0-1.3-2.0
Locomotion distance, session 81.21.73.41.2-1.3-0.7-1.4-0.9-1.2-1.81.8-1.9-1.3-0.5-1.0
Degree of sensitization distance0.50.53.2-0.70.41.8-0.00.70.6-0.00.0-0.20.30.80.5
Degree of sensitization stereotypy0.50.61.70.8-0.7-1.3-0.9-0.9-0.8-0.30.3-0.1-0.5-0.9-0.7
Condit. Reinf. active minus inactive responses0.60.70.9-0.80.90.80.70.80.90.9-0.90.90.70.60.8
Condit. Reinf. active-inactive response ratio4.54.96.8-2.32.62.12.12.22.42.1-2.21.92.22.02.3
Condit. Reinf. active responses0.10.10.2-0.40.40.30.30.40.40.3-0.20.20.20.30.4
Condit. Reinf. inactive responses1.72.02.71.6-1.6-1.4-1.3-1.4-1.5-1.41.4-1.2-1.4-1.3-1.4
Incentive salience index mean0.10.10.40.5-0.2-0.4-0.3-0.5-0.20.1-0.10.2-0.3-0.6-0.3
Condit. Reinf. lever presses0.20.31.21.1-0.4-0.6-0.6-0.7-0.40.1-0.00.3-0.3-0.9-0.4
Time in familiar zone, hab. session 10.30.30.6-0.80.50.60.80.50.50.6-0.50.50.40.40.4
Time in novel zone, hab. session 10.10.10.60.20.30.0-0.1-0.20.10.6-0.60.80.2-0.40.1
Total zone transitions, hab. session 12.63.65.52.0-2.0-2.1-1.5-2.2-2.0-1.31.5-1.1-2.2-2.3-2.0
Total locomotion distance, hab. session 10.00.00.10.4-0.1-0.1-0.1-0.10.00.10.00.1-0.3-0.20.0
Locomotion velocity, hab. session 10.20.30.70.5-0.5-0.4-0.5-0.3-0.4-0.80.8-0.8-0.6-0.1-0.2
Time in familiar zone, hab. session 20.80.82.5-1.40.71.60.31.00.90.4-0.40.20.81.10.8
Time in novel zone, hab. session 20.40.41.00.9-0.3-0.90.1-0.8-0.50.1-0.00.2-0.7-1.0-0.5
Total zone transitions, hab. session 20.10.10.30.3-0.2-0.5-0.50.1-0.2-0.50.4-0.50.10.30.0
Total locomotion distance, hab. session 20.30.41.5-0.40.30.3-0.00.90.5-0.40.3-0.60.61.20.8
Locomotion velocity, hab. session 20.30.41.6-0.40.30.20.01.00.5-0.40.3-0.60.61.30.8
Novel to familiar place preference ratio0.00.00.3-0.50.00.10.1-0.0-0.00.1-0.10.10.1-0.1-0.2
Novelty place preference0.00.00.3-0.60.00.10.10.00.00.2-0.20.20.1-0.1-0.1
Time in novel zone, NPP test0.00.10.3-0.5-0.10.0-0.0-0.2-0.10.2-0.20.2-0.1-0.3-0.3
Total zone transitions, NPP test1.41.92.71.6-1.5-1.4-1.4-1.2-1.4-1.51.5-1.5-1.3-1.0-1.2
Total locomotion distance, NPP test0.71.01.81.3-1.0-1.0-1.2-0.7-0.9-1.21.2-1.1-0.8-0.5-0.7
Locomotion velocity, NPP test0.60.81.81.3-0.8-1.0-1.1-0.6-0.8-1.01.0-1.0-0.7-0.4-0.6
Pavlov. Cond. lever latency0.81.02.5-1.60.91.00.81.01.01.0-1.00.80.90.90.9
Pavlov. Cond. magazine entry latency1.92.54.02.0-1.4-1.9-1.0-1.9-1.6-1.11.2-0.9-1.8-1.9-1.6
Pavlov. Cond. change in total contacts2.12.34.92.2-1.4-1.7-1.2-1.7-1.6-1.21.3-1.0-1.5-1.6-1.3
Pavlov. Cond. index score2.02.54.82.2-1.5-1.8-1.3-1.8-1.7-1.31.3-1.0-1.6-1.8-1.5
Pavlov. Cond. latency score1.72.23.81.9-1.4-1.7-1.1-1.6-1.6-1.31.3-1.1-1.5-1.6-1.5
Pavlov. Cond. lever contacts0.91.12.91.7-0.9-1.1-0.9-1.2-1.1-0.70.8-0.5-0.9-1.1-1.0
Pavlov. Cond. magazine entry number2.63.36.5-2.61.72.21.52.11.81.1-1.30.91.92.21.7
Pavlov. Cond. intertrial magazine entries0.60.71.5-1.20.80.60.91.10.80.4-0.50.20.81.10.9
Pavlov. Cond. lever-magazine prob. diff.1.51.83.92.0-1.2-1.5-1.2-1.5-1.4-1.11.1-0.9-1.4-1.5-1.2
Pavlov. Cond. response bias1.82.25.22.3-1.3-1.7-1.2-1.8-1.5-0.91.0-0.7-1.5-1.8-1.4
Bone: apparent density2.13.55.1-1.41.82.00.81.72.02.2-2.32.22.31.41.7
Bone surface0.91.63.8-0.51.01.40.10.81.31.8-1.81.91.50.51.0
Bone volume1.93.25.7-0.91.71.80.61.51.82.2-2.32.42.21.21.7
Bone: connectivity density0.81.32.2-0.61.01.30.31.01.21.5-1.51.51.20.70.9
Bone: cortical apparent density4.96.38.0-2.22.72.02.32.52.82.8-2.82.72.62.02.7
Bone: cortical area0.50.82.61.1-0.1-0.3-0.5-0.8-0.11.2-1.11.6-0.0-1.4-0.4
Bone: cortical porosity1.51.62.61.0-1.4-1.0-1.3-1.0-1.3-1.61.6-1.6-1.3-0.7-1.2
Bone: cortical porosity1.71.82.61.1-1.5-1.2-1.1-1.2-1.5-1.61.6-1.6-1.4-0.9-1.4
Bone: cortical thickness1.52.57.5-0.11.41.00.80.71.52.5-2.42.71.40.11.2
Bone: cortical thickness0.30.30.6-0.40.60.40.70.50.70.8-0.70.70.40.30.5
Bone: cortical tissue density5.47.08.4-2.42.82.12.42.72.92.9-2.92.72.72.32.8
Bone: elastic displacement0.70.82.3-1.40.50.70.61.30.8-0.20.1-0.60.61.50.8
Bone: elastic work0.20.20.9-0.3-0.4-0.1-0.10.1-0.3-0.80.7-0.9-0.30.3-0.4
Bone: endosteal estimation0.92.03.31.0-1.6-1.4-0.7-1.5-1.6-1.31.4-1.2-1.5-1.5-1.8
Bone: endosteal perimeter1.63.34.91.8-2.0-1.7-1.8-2.2-2.0-1.21.3-0.9-1.8-2.2-2.2
Bone: final force0.40.61.31.0-0.7-0.8-0.2-1.0-0.8-0.30.4-0.2-0.9-1.2-1.0
Bone: final moment0.20.30.80.8-0.4-0.60.1-0.8-0.6-0.10.20.0-0.6-0.9-0.7
Bone: marrow area0.91.93.21.0-1.6-1.3-0.7-1.5-1.6-1.31.3-1.2-1.5-1.4-1.8
Bone: maximum diameter0.40.72.31.2-0.6-0.8-0.8-1.1-0.60.5-0.40.9-0.5-1.5-0.8
Bone: maximum force0.61.02.51.4-0.9-1.1-0.5-1.4-1.0-0.10.20.2-0.9-1.6-1.2
Bone: maximum moment0.30.61.71.2-0.6-0.9-0.2-1.1-0.70.1-0.00.4-0.6-1.3-0.9
Bone: minimum diameter0.40.82.01.1-1.0-0.7-0.8-1.2-0.9-0.20.3-0.1-1.0-1.4-1.1
Bone: periosteal estimation0.51.02.81.4-1.0-0.9-0.7-1.4-0.90.00.10.3-0.9-1.7-1.2
Bone: periosteal perimeter1.11.83.31.7-1.4-1.2-1.5-1.7-1.4-0.60.7-0.3-1.3-1.8-1.5
Bone: post-yield work0.50.61.80.10.80.50.30.40.71.1-1.21.31.00.20.8
Bone: stiffness2.23.56.52.1-1.8-2.1-1.0-2.4-2.1-1.11.2-0.8-2.0-2.6-2.2
Bone: tissue strength1.21.12.3-0.91.00.71.50.60.91.5-1.41.50.80.20.6
Bone: trabecular number1.21.93.6-1.01.21.60.51.11.51.9-1.81.91.40.71.1
Bone: trabecular spacing0.20.31.10.2-0.2-0.60.20.0-0.4-0.90.9-1.0-0.30.4-0.0
Bone: trabecular thickness1.51.83.6-0.71.51.10.71.11.41.8-1.81.91.60.81.2
Bone: trabecular tissue density2.43.35.52.0-1.9-2.3-1.4-1.8-1.9-1.71.7-1.5-1.8-1.7-1.8
Breakpoint value in progressive ratio session0.20.32.11.40.0-0.5-0.2-0.5-0.20.1-0.10.4-0.1-0.60.1
Distance traveled before self-admin0.40.51.4-0.10.60.40.80.70.4-0.60.5-0.70.41.20.9
Distance traveled after self-admin0.20.20.70.7-0.2-0.90.4-0.4-0.4-0.40.4-0.3-0.4-0.3-0.1
Delta time in closed arm before/after self-admin2.42.44.30.9-1.5-1.2-1.5-1.9-1.8-1.11.2-1.0-1.7-2.0-2.1
Delta time in open arm before/after self-admin1.21.22.8-1.60.90.90.91.41.00.2-0.3-0.01.21.71.3
Diff in mean of infusions in LGA sessions0.10.10.50.70.3-0.30.10.00.20.3-0.30.50.40.10.6
Extinction: sum of active levers before priming0.20.20.7-0.1-0.20.4-0.50.40.1-0.70.6-0.80.30.80.3
Active lever presses in extinction session 60.70.61.80.10.70.70.71.00.80.0-0.1-0.00.91.31.3
Delta distance traveled before/after self-admin0.30.41.30.3-0.6-0.7-0.1-0.8-0.50.2-0.10.3-0.7-1.1-0.7
Delta ambulatory time before/after self-admin0.20.20.70.4-0.1-0.50.3-0.5-0.10.6-0.50.7-0.3-0.8-0.2
Time in closed arm before self-admin0.30.30.70.20.0-0.10.60.60.60.5-0.60.60.80.60.7
Time in closed arm after self-admin1.01.12.91.7-0.9-1.5-0.7-1.3-1.0-0.30.30.1-0.7-1.4-1.0
Time in open arm before self-admin0.20.20.8-0.40.70.9-0.20.20.40.4-0.30.30.10.20.1
Time in open arm after self-admin1.01.12.0-1.41.41.10.81.21.00.4-0.50.31.11.41.2
Sum of active levers in priming session hrs 5-60.10.10.2-0.1-0.40.3-0.40.0-0.1-0.40.4-0.4-0.20.1-0.2
Time to tail flick, vehicle, before self-admin0.10.10.30.3-0.1-0.30.60.10.20.2-0.20.20.30.10.2
Time to tail flick, vehicle, after self-admin1.61.73.21.5-1.5-1.3-1.6-0.7-1.1-1.81.7-1.7-0.7-0.1-0.7
Time to tail flick, test, before self-admin0.70.72.71.5-0.7-1.60.2-0.7-0.6-0.70.7-0.6-0.6-0.5-0.1
Time to tail flick, test, after self-admin0.40.41.6-0.4-0.1-0.30.50.5-0.1-1.10.9-1.30.11.00.3
Delta time to tail flick, vehicle, before/after SA0.50.51.7-0.0-0.4-0.3-0.60.2-0.4-1.21.1-1.3-0.00.70.0
Delta time to tail flick, test, before/after SA0.20.20.6-0.80.30.6-0.10.60.2-0.20.1-0.30.30.70.3
Ambulatory time before self-admin0.30.30.60.60.3-0.10.40.3-0.0-0.80.7-0.80.20.80.7
Ambulatory time after self-admin0.40.41.31.1-0.5-1.00.4-0.6-0.6-0.70.7-0.7-0.6-0.4-0.2
Total heroin consumption0.20.20.80.40.40.30.50.50.50.2-0.20.20.60.70.9
Area under the delay curve1.31.42.40.9-1.1-0.7-1.5-1.3-1.3-1.11.1-1.0-1.4-1.3-1.5
Delay disc. indifference point, 0s delay0.00.00.10.2-0.00.1-0.2-0.1-0.1-0.20.2-0.2-0.1-0.0-0.1
Delay disc. indifference point, 16s delay1.01.02.30.9-0.8-0.7-1.5-0.8-1.0-1.11.1-1.1-0.9-0.6-1.1
Delay disc. indifference point, 2s delay0.40.52.10.3-0.50.1-1.4-0.7-0.6-0.50.6-0.5-0.7-0.7-0.9
Delay disc. indifference point, 24s delay0.80.82.10.9-0.2-1.0-1.5-0.8-1.1-1.00.9-0.9-0.4-0.5-1.0
Delay disc. indifference point, 4s delay0.00.00.2-0.2-0.10.5-0.3-0.1-0.0-0.00.0-0.0-0.1-0.1-0.2
Delay disc. indifference point, 8s delay0.40.51.20.2-0.6-0.3-0.4-0.7-0.6-0.60.7-0.6-1.1-0.8-0.9
Delay discount exponential model param1.11.22.2-0.70.90.51.51.21.10.9-1.00.91.31.21.4
Delay discount hyperbolic model param1.01.12.1-0.70.90.41.51.11.10.9-1.00.91.21.11.3
Fecal boli incidents, locomotor time 13.13.36.81.2-1.7-1.7-1.9-1.2-2.0-2.62.4-2.6-1.3-0.5-1.6
Change in fecal boli incidents, locomotor task0.50.51.6-1.10.41.01.30.40.60.7-0.70.60.20.10.3
Time >=10cm from walls, locomotor time 10.30.30.7-0.80.30.50.40.30.40.8-0.80.80.60.10.1
Bouts of movement, locomotor time 10.70.71.30.4-0.6-1.10.5-0.8-0.9-1.01.0-1.1-1.0-0.6-0.7
Total resting periods, locomotor time 10.91.02.00.7-0.7-1.4-0.1-1.1-1.2-1.11.1-1.0-1.1-0.9-1.1
Rest time, locomotor task time 11.01.12.61.0-0.8-1.3-1.6-0.9-1.1-0.80.8-0.8-0.8-0.9-1.2
Distance moved, locomotor task time 10.50.61.8-0.20.60.70.70.90.90.5-0.50.40.91.01.3
Vertical activity count, locomotor time 11.01.01.6-0.70.91.20.70.91.21.2-1.11.10.90.71.2
Time >=10cm from walls, locomotor time 20.20.20.60.80.2-0.8-0.3-0.4-0.4-0.30.3-0.2-0.3-0.3-0.3
Bouts of movement, locomotor time 20.50.51.51.0-0.6-0.9-0.5-1.0-0.60.2-0.10.4-0.5-1.2-0.6
Total resting periods, locomotor time 20.40.41.10.9-0.6-1.0-0.4-0.9-0.6-0.00.10.2-0.6-1.1-0.6
Rest time, locomotor task time 22.12.43.31.0-1.7-1.6-1.3-1.6-1.8-1.51.6-1.5-1.7-1.5-1.8
Distance moved, locomotor task time 22.22.66.10.11.80.81.51.71.91.4-1.51.41.91.72.5
Vertical activity count, locomotor time 24.85.38.3-0.72.52.01.42.22.62.5-2.62.62.72.12.9
Weight adjusted by age0.60.71.90.70.4-1.40.2-0.6-1.0-1.31.1-1.2-0.5-0.2-0.5
Seeking ratio, delayed vs. immediate footshock0.80.91.7-0.2-1.2-0.5-0.3-0.9-1.0-0.91.0-1.1-1.2-0.9-1.3
Locomotion in novel chamber2.02.45.00.6-1.6-1.5-1.9-1.7-1.7-1.11.1-0.9-1.6-1.9-2.2
Locomotion in novel chamber post-restriction1.21.53.20.8-1.5-0.9-1.6-1.5-1.2-0.20.30.0-1.1-1.8-1.8
Progressive ratio2.73.15.72.1-2.1-1.7-2.4-1.6-1.7-1.61.6-1.4-1.5-1.4-1.6
Food seeking constrained by brief footshock0.20.21.1-0.50.50.31.10.30.30.3-0.30.20.20.30.4
Seeking ratio, punishment vs. effort2.42.96.6-1.92.21.42.61.51.71.6-1.61.41.31.21.6
Run reversals in cocaine runway, females0.70.71.4-1.20.61.10.41.01.01.0-0.90.80.60.60.4
Run reversals in cocaine runway, males0.10.10.2-0.00.10.00.20.10.20.4-0.40.40.20.00.1
Latency to leave start box in cocaine runway0.10.10.50.5-0.10.0-0.70.1-0.0-0.40.4-0.40.10.30.1
Latency to leave start box in cocaine runway, F0.10.10.30.10.10.4-0.50.20.20.2-0.20.30.40.30.1
Latency to leave start box in cocaine runway, M0.50.51.50.6-0.4-0.5-0.2-0.2-0.5-1.21.1-1.2-0.50.2-0.0
Cd content in liver1.41.53.5-1.51.91.01.71.41.10.6-0.60.31.01.41.0
Co content in liver0.10.20.50.0-0.3-0.0-0.20.40.0-0.60.5-0.70.20.70.2
Cu content in liver0.60.71.9-0.51.30.30.81.00.7-0.10.0-0.30.81.41.3
Fe content in liver4.35.17.3-1.12.72.01.52.02.42.6-2.72.72.61.72.4
K content in liver0.50.52.81.70.5-0.9-0.5-0.4-0.5-0.60.6-0.5-0.3-0.3-0.1
Mg content in liver0.80.93.51.90.1-1.3-0.5-0.6-0.8-1.11.1-1.1-0.6-0.2-0.2
Mn content in liver0.40.40.90.50.4-0.6-0.2-0.5-0.7-0.90.9-0.9-0.8-0.4-0.6
Na content in liver1.71.82.81.5-1.0-1.7-1.0-1.3-1.4-1.41.4-1.3-1.4-1.2-1.2
Rb content in liver3.13.95.4-1.32.02.21.72.12.31.9-1.91.72.01.92.3
Se content in liver1.21.53.1-0.71.81.11.01.51.30.6-0.70.51.41.71.5
Sr content in liver1.31.22.21.4-1.1-1.0-1.5-1.1-1.0-1.01.0-0.9-1.0-0.9-0.8
Zn content in liver1.21.32.50.9-0.8-1.6-0.5-1.0-1.3-1.51.4-1.4-1.1-0.7-0.9