Hub : Genes

Pnpo

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000046493 0.4 0.11 0.0e+00 0.47 0.49 0.48 0.48 1.7e-58 3.5e-61 1.9e-60 1.4e-60
2 Adipose isoform ratio ENSRNOT00000073746 0.02 0.01 4.7e-03 0 0.01 -0 0 1.4e-01 5.2e-02 9.3e-01 2.4e-01
3 Adipose isoform ratio ENSRNOT00000111538 0.02 0.01 5.4e-03 0 0.01 -0 0 1.5e-01 6.3e-02 8.5e-01 2.8e-01
4 BLA gene expression ENSRNOG00000046493 0.76 0.03 0.0e+00 0.64 0.69 0.69 0.71 3.5e-44 4.6e-50 2.0e-50 3.0e-52
5 BLA isoform ratio ENSRNOT00000073746 0.07 0.05 1.0e-03 0.04 0.05 0.04 0.05 3.4e-03 1.3e-03 3.5e-03 1.7e-03
6 BLA isoform ratio ENSRNOT00000111538 0.07 0.06 7.9e-04 0.04 0.05 0.04 0.05 2.8e-03 9.9e-04 2.5e-03 1.3e-03
7 Brain gene expression ENSRNOG00000046493 0.79 0.04 0.0e+00 0.75 0.76 0.77 0.77 4.5e-104 3.0e-108 5.0e-109 2.7e-109
8 Brain isoform ratio ENSRNOT00000073746 0.07 0.05 3.5e-07 0.06 0.07 0.06 0.06 5.6e-06 7.0e-07 2.0e-06 2.8e-06
9 Brain isoform ratio ENSRNOT00000111538 0.07 0.05 3.7e-07 0.06 0.07 0.06 0.06 6.0e-06 7.0e-07 1.5e-06 3.0e-06
10 Brain mRNA stability ENSRNOG00000046493 0.03 0.02 9.6e-04 0.03 0.03 0.02 0.03 1.6e-03 1.1e-03 7.3e-03 1.9e-03
11 IL gene expression ENSRNOG00000046493 0.86 0.08 0.0e+00 0.44 0.37 0.44 0.42 6.2e-12 8.4e-10 9.8e-12 2.2e-11
12 LHb gene expression ENSRNOG00000046493 0.83 0.08 0.0e+00 0.5 0.5 0.51 0.51 1.1e-13 1.4e-13 4.2e-14 4.2e-14
13 Liver gene expression ENSRNOG00000046493 0.17 0.07 0.0e+00 0.3 0.3 0.3 0.3 2.6e-33 8.1e-34 1.5e-33 6.3e-34
14 NAcc gene expression ENSRNOG00000046493 0.43 0.03 0.0e+00 0.71 0.75 0.74 0.75 3.1e-74 1.4e-83 4.4e-81 9.1e-83
15 NAcc isoform ratio ENSRNOT00000073746 0.06 0.05 2.1e-03 0.03 0.03 0.03 0.03 1.4e-03 2.0e-03 2.1e-03 1.3e-03
16 NAcc isoform ratio ENSRNOT00000111538 0.06 0.05 1.6e-03 0.04 0.03 0.03 0.04 9.6e-04 1.6e-03 1.5e-03 9.0e-04
17 OFC gene expression ENSRNOG00000046493 0.98 0.01 0.0e+00 0.45 0.51 0.45 0.42 5.6e-12 4.6e-14 5.9e-12 2.5e-11
18 OFC mRNA stability ENSRNOG00000046493 0.24 0.16 7.6e-03 0.01 0.02 0.06 0.04 1.9e-01 1.3e-01 1.8e-02 4.0e-02
19 PL gene expression ENSRNOG00000046493 0.51 0.03 0.0e+00 0.7 0.74 0.74 0.75 7.7e-74 5.5e-83 1.1e-82 3.7e-84
20 PL mRNA stability ENSRNOG00000046493 0.03 0.03 9.9e-03 0.02 0.02 0.01 0.01 1.3e-02 1.9e-02 2.8e-02 2.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
BMI with tail11.738.042.6-6.2-6.36.3-6.0-6.36.3-6.1-6.26.2-6.1-6.1-6.2-6.3-6.2-6.36.3-6.5-6.5-6.2-4.3
BMI without tail1.42.93.5-1.9-1.51.5-1.7-1.81.8-1.8-1.81.8-1.6-1.8-1.8-1.8-1.7-1.81.8-1.7-1.7-1.7-0.5
Body weight0.62.615.1-1.7-1.00.9-1.1-1.41.5-1.3-1.61.5-0.9-1.4-1.2-1.4-1.1-1.41.4-1.7-3.9-1.32.1
Epididymis fat weight0.00.10.9-0.20.0-0.10.1-0.10.10.1-0.20.20.0-0.1-0.0-0.10.10.1-0.1-0.1-0.40.10.9
Glucose0.40.71.2-1.1-0.60.6-0.8-0.90.9-0.9-1.11.1-0.9-0.8-0.9-0.9-0.7-0.70.7-0.8-0.3-0.90.4
Heart weight1.21.84.4-1.2-1.21.2-1.2-1.31.3-1.3-1.31.3-1.1-1.1-1.3-1.2-1.3-1.51.5-1.4-2.1-1.4-0.1
Left kidney weight0.20.68.4-0.20.6-0.70.20.1-0.00.0-0.10.10.5-0.10.30.20.30.2-0.20.0-1.50.12.9
Right kidney weight0.41.13.0-1.2-0.60.5-0.8-1.01.0-1.0-1.21.2-0.7-1.0-0.9-0.9-0.7-0.80.8-1.0-1.7-0.91.7
Tail length10.230.848.35.06.1-6.25.55.4-5.45.45.2-5.25.85.25.75.55.85.5-5.55.63.75.66.9
Length with tail6.824.855.64.45.5-5.65.04.8-4.74.84.5-4.65.44.75.14.85.25.0-5.04.71.75.07.5
Length without tail0.40.95.00.50.9-0.90.90.7-0.60.80.6-0.61.00.60.90.70.90.9-0.90.5-1.20.82.2
Liver weight, left0.81.31.61.21.2-1.21.21.2-1.21.21.1-1.11.21.11.11.21.11.3-1.31.10.81.21.0
Liver weight, right1.22.15.11.21.7-1.71.41.4-1.31.31.1-1.21.51.31.21.31.41.5-1.51.41.31.32.3
Parametrial fat weight0.00.10.3-0.4-0.20.2-0.4-0.30.3-0.4-0.30.3-0.3-0.5-0.4-0.3-0.3-0.00.0-0.10.5-0.3-0.1
Retroperitoneal fat weight0.41.32.1-1.4-0.80.8-1.0-1.21.2-1.1-1.41.4-1.0-1.2-1.2-1.2-0.9-0.90.9-1.1-1.1-1.11.1
Intraocular pressure1.01.43.21.11.4-1.41.01.2-1.21.01.2-1.21.41.01.21.11.11.3-1.31.20.31.21.8
Extensor digitorum longus weight0.31.013.8-0.7-0.50.5-0.5-0.60.7-0.6-0.50.5-0.1-0.4-0.1-0.6-0.4-0.40.4-1.0-3.7-0.51.4
Soleus weight0.92.73.6-1.9-1.61.6-1.6-1.81.8-1.7-1.91.9-1.8-1.7-1.8-1.7-1.6-1.71.7-1.6-0.8-1.7-0.6
Tibialis anterior weight0.30.91.70.80.9-0.90.90.9-0.80.90.9-0.91.10.91.10.91.01.0-1.00.7-0.51.01.3
Tibia length0.41.13.2-1.2-0.80.8-1.0-1.11.1-1.1-1.11.1-0.8-1.1-0.8-1.1-0.8-0.80.8-1.1-1.8-1.00.9
Number of licking bursts0.10.10.40.30.2-0.20.20.3-0.30.30.3-0.30.20.20.30.30.20.4-0.40.30.60.3-0.4
Food consumed during 24 hour testing period1.31.51.91.31.2-1.21.21.3-1.31.31.3-1.41.41.21.41.31.21.3-1.31.20.41.31.0
Times rat made contact with spout0.10.10.40.20.1-0.10.10.2-0.20.20.2-0.20.10.10.20.20.10.2-0.20.30.60.2-0.4
Mean time between licks in bursts0.10.10.9-0.3-0.40.4-0.3-0.30.3-0.4-0.30.3-0.2-0.3-0.2-0.3-0.3-0.30.3-0.4-1.0-0.4-0.1
Mean num. licks in bursts0.00.10.10.20.2-0.20.20.2-0.20.20.2-0.20.20.30.20.20.20.1-0.10.20.30.20.4
Std. dev. time between licks in bursts1.21.52.0-1.2-1.31.3-1.2-1.21.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.2-1.31.3-1.3-1.4-1.2-1.0
Water consumed over 24 hours0.20.20.30.60.4-0.40.40.5-0.50.50.6-0.60.50.50.50.50.40.5-0.50.50.50.5-0.1
Indifference point 0 sec1.01.52.0-1.4-1.21.1-1.3-1.31.3-1.2-1.41.4-1.4-1.3-1.4-1.3-1.2-1.41.4-1.2-0.3-1.3-0.5
Indifference point AUC0.10.20.30.50.3-0.30.30.5-0.50.40.5-0.50.40.50.50.40.30.5-0.50.40.10.4-0.1
Indifference point function ln k0.00.00.2-0.3-0.0-0.0-0.2-0.20.2-0.2-0.20.2-0.1-0.3-0.1-0.20.00.1-0.1-0.10.0-0.10.5
Indifference point function log k0.00.00.2-0.3-0.0-0.0-0.2-0.20.2-0.2-0.20.2-0.1-0.3-0.1-0.20.00.1-0.1-0.10.0-0.10.5
Delay discounting total patch changes 0 sec0.91.52.0-1.4-1.11.1-1.3-1.31.3-1.3-1.41.4-1.3-1.3-1.4-1.3-1.1-1.41.4-1.2-0.5-1.3-0.3
Delay discounting total patch changes 12 sec0.30.30.6-0.6-0.50.5-0.7-0.50.5-0.6-0.60.6-0.7-0.6-0.7-0.6-0.6-0.40.4-0.30.8-0.6-0.8
Delay discounting total patch changes 18 sec1.41.82.3-1.3-1.51.5-1.3-1.41.4-1.3-1.31.3-1.5-1.1-1.3-1.4-1.3-1.31.3-1.4-1.0-1.3-1.5
Delay discounting total patch changes 24 sec1.51.82.8-1.3-1.31.3-1.3-1.41.4-1.2-1.41.4-1.5-1.3-1.6-1.4-1.4-1.71.7-1.3-0.5-1.4-0.9
Delay discounting total patch changes 6 sec0.91.42.3-1.2-1.21.2-1.3-1.21.2-1.2-1.21.2-1.3-1.2-1.2-1.2-1.2-1.01.0-1.1-0.5-1.1-1.5
Delay discounting time to switch 0 sec0.10.10.5-0.3-0.40.4-0.4-0.30.3-0.3-0.30.3-0.4-0.4-0.4-0.3-0.5-0.30.3-0.3-0.1-0.3-0.7
Delay discounting water rate 0 sec0.61.01.3-1.1-0.80.8-1.0-1.01.0-1.1-1.11.1-0.9-0.9-1.0-1.1-0.8-1.21.2-1.0-1.1-1.10.5
Delay discounting water rate 12 sec0.10.21.80.20.5-0.50.40.3-0.30.30.2-0.20.50.40.40.30.60.4-0.40.3-0.00.41.4
Delay discounting water rate 18 sec0.70.92.00.81.0-1.11.00.8-0.80.90.7-0.70.81.00.80.91.10.5-0.51.01.40.81.4
Delay discounting water rate 24 sec0.50.71.0-1.0-0.80.8-0.8-0.90.9-0.9-1.01.0-0.9-0.8-0.9-0.9-0.6-1.01.0-0.8-0.3-0.9-0.1
Delay discounting water rate 6 sec0.10.10.80.30.3-0.30.30.3-0.30.30.2-0.20.20.50.20.30.30.1-0.10.30.90.20.2
Locomotor activity0.71.12.1-0.9-1.11.1-1.0-1.00.9-1.0-0.90.9-1.1-1.1-1.1-1.1-1.1-1.11.1-0.9-0.3-1.0-1.4
Locomotor testing distance1.22.05.8-1.2-1.61.6-1.4-1.31.3-1.4-1.21.2-1.6-1.4-1.5-1.4-1.4-1.41.4-1.20.2-1.4-2.4
Locomotor testing rearing0.20.32.40.1-0.30.4-0.2-0.10.0-0.2-0.10.1-0.4-0.1-0.5-0.2-0.2-0.30.30.01.5-0.2-1.4
Light reinforcement 10.40.83.1-0.7-1.01.0-0.8-0.80.7-0.7-0.70.8-1.0-0.7-0.9-0.8-0.8-0.90.9-0.70.5-0.8-1.8
Light reinforcement 20.10.10.3-0.2-0.30.3-0.3-0.20.2-0.3-0.20.2-0.3-0.3-0.3-0.3-0.3-0.20.2-0.20.3-0.2-0.5
Reaction time number correct0.20.20.70.50.4-0.40.60.5-0.50.50.5-0.50.50.80.50.50.60.3-0.30.4-0.10.40.6
Reaction time mean minus median0.30.41.10.60.4-0.40.40.6-0.60.50.7-0.70.60.30.80.50.41.0-1.00.60.30.7-0.6
Reaction time mean minus median AUC0.50.61.30.80.5-0.50.50.7-0.80.60.9-0.90.60.50.90.60.51.1-1.10.81.00.8-1.0
Reaction time num false alarms0.20.31.10.60.5-0.50.70.5-0.50.60.5-0.50.40.70.60.60.70.3-0.30.61.10.60.4
Reaction time num false alarms AUC0.30.51.20.60.6-0.60.80.6-0.60.70.6-0.60.50.80.70.60.90.4-0.40.71.10.70.6
Reaction time trials correct on left0.20.20.70.50.4-0.40.60.5-0.50.50.5-0.50.50.80.50.50.60.3-0.30.4-0.10.40.6
Reaction time trials on left0.20.20.60.50.4-0.40.60.5-0.50.50.5-0.50.50.80.50.50.60.3-0.30.4-0.10.40.5
Reaction time mean0.10.22.0-0.2-0.40.5-0.6-0.20.2-0.4-0.00.1-0.3-0.6-0.0-0.4-0.50.2-0.2-0.2-0.3-0.2-1.4
Reaction time mean AUC0.10.21.8-0.1-0.40.4-0.5-0.20.2-0.40.0-0.0-0.2-0.60.0-0.3-0.50.3-0.3-0.2-0.3-0.1-1.3
Median of all reaction times0.40.52.9-0.5-0.80.8-0.9-0.60.6-0.7-0.40.4-0.7-0.9-0.5-0.7-0.9-0.30.3-0.6-0.4-0.6-1.7
Reaction time omissions0.00.00.2-0.1-0.00.0-0.3-0.00.0-0.2-0.00.0-0.1-0.40.0-0.2-0.20.4-0.40.10.5-0.0-0.1
Reaction time false alarm rate0.10.10.80.10.2-0.20.20.2-0.20.20.2-0.10.10.20.20.20.30.1-0.10.30.90.20.2
Reaction time premature initiation rate0.30.40.80.50.7-0.70.60.6-0.60.70.6-0.60.60.50.70.60.70.7-0.70.70.90.70.3
Reaction time premature initiations0.60.91.30.91.0-1.01.00.9-0.91.00.9-0.90.91.01.00.91.10.9-0.91.00.71.00.7
Std. dev. reaction times0.10.20.60.30.2-0.20.10.3-0.40.20.5-0.50.30.10.50.20.20.8-0.80.40.30.4-0.6
Reaction time trials completed0.20.20.60.50.4-0.40.60.5-0.50.50.5-0.50.50.80.50.50.60.3-0.30.4-0.10.40.5
Reaction time trials AUC0.20.30.70.60.4-0.40.60.5-0.50.50.5-0.50.50.90.50.60.70.3-0.30.40.00.50.5
Social response proportion0.70.72.70.71.0-1.10.70.8-0.80.70.7-0.70.90.70.80.80.90.7-0.70.90.90.71.7
Social responses0.00.00.40.10.2-0.2-0.00.1-0.10.00.1-0.10.1-0.10.00.10.0-0.10.10.20.40.00.6
Social time0.00.00.40.1-0.20.2-0.10.0-0.00.00.2-0.2-0.0-0.30.0-0.0-0.2-0.10.1-0.00.0-0.0-0.6
Conditioned locomotion1.01.21.5-1.2-1.01.0-1.2-1.11.1-1.2-1.21.2-1.1-1.2-1.1-1.2-1.1-1.01.0-1.1-0.8-1.1-0.4
Cocaine response after cond. corrected5.86.57.6-2.8-2.42.4-2.8-2.62.6-2.7-2.72.7-2.6-2.8-2.7-2.7-2.6-2.52.5-2.5-1.5-2.7-1.2
Cocaine response after cond. not corrected3.23.64.6-2.2-1.71.7-2.1-2.02.0-2.1-2.22.1-2.0-2.1-2.1-2.0-1.9-1.91.9-1.8-0.7-2.0-0.5
Cocaine response before conditioning2.42.94.61.71.8-1.81.71.7-1.71.81.6-1.61.61.71.61.71.71.7-1.71.82.11.71.2
Saline control response0.20.30.90.60.5-0.50.50.6-0.60.40.6-0.50.40.70.40.60.60.3-0.30.61.00.40.0
Condit. Reinf. active minus inactive responses0.10.20.3-0.4-0.40.4-0.4-0.40.4-0.4-0.40.4-0.5-0.2-0.4-0.4-0.3-0.40.4-0.30.2-0.4-0.5
Condit. Reinf. active-inactive response ratio0.40.51.0-0.6-0.80.8-0.7-0.70.7-0.7-0.60.6-0.8-0.5-0.6-0.7-0.6-0.70.7-0.7-0.2-0.7-1.0
Condit. Reinf. active responses0.00.00.5-0.1-0.10.1-0.1-0.10.1-0.1-0.10.1-0.20.0-0.1-0.10.0-0.00.00.00.7-0.0-0.4
Condit. Reinf. inactive responses0.30.42.10.50.5-0.50.50.5-0.60.60.5-0.50.40.50.40.50.50.5-0.50.71.40.6-0.2
Condit. Reinf. lever presses0.60.91.10.90.9-0.90.90.9-0.90.90.9-0.90.90.91.00.91.01.0-1.01.01.01.00.4
Condit. Reinf. lever reinforcers received0.10.10.80.20.1-0.10.10.2-0.20.20.1-0.10.00.30.10.20.30.2-0.20.30.90.2-0.2
Pavlov. Cond. lever latency0.50.70.90.90.9-0.90.80.9-0.90.80.9-0.90.90.80.90.90.80.9-0.90.90.50.90.8
Pavlov. Cond. magazine entry latency0.50.61.50.60.8-0.80.80.7-0.70.80.6-0.60.70.70.80.70.80.7-0.70.70.50.71.2
Pavlov. Cond. change in total contacts0.20.30.4-0.6-0.60.6-0.6-0.50.5-0.6-0.60.6-0.6-0.4-0.5-0.5-0.5-0.50.5-0.50.0-0.5-0.6
Pavlov. Cond. index score0.20.30.4-0.7-0.50.5-0.6-0.60.6-0.5-0.70.6-0.6-0.6-0.6-0.6-0.5-0.60.6-0.5-0.3-0.6-0.1
Pavlov. Cond. latency score0.10.10.2-0.5-0.30.3-0.3-0.40.4-0.3-0.50.5-0.4-0.4-0.3-0.4-0.3-0.40.4-0.3-0.2-0.40.2
Pavlov. Cond. lever contacts0.40.60.8-0.8-0.80.8-0.8-0.80.8-0.8-0.80.8-0.9-0.7-0.8-0.8-0.8-0.80.8-0.7-0.1-0.8-0.9
Pavlov. Cond. magazine entry number0.00.00.30.2-0.10.10.10.1-0.10.10.2-0.20.10.10.00.1-0.00.0-0.00.0-0.10.1-0.6
Pavlov. Cond. intertrial magazine entries1.82.32.81.71.5-1.41.61.6-1.61.51.7-1.71.61.61.61.61.51.7-1.71.50.61.60.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.7-0.60.6-0.6-0.70.7-0.6-0.70.7-0.7-0.6-0.6-0.6-0.6-0.60.6-0.6-0.4-0.6-0.0
Pavlov. Cond. response bias0.40.60.8-0.8-0.80.8-0.8-0.80.8-0.8-0.90.9-0.9-0.7-0.8-0.8-0.7-0.80.8-0.7-0.1-0.8-0.6
Conditioned reinforcement - actives1.41.42.9-1.2-1.31.3-1.2-1.21.2-1.1-1.21.2-1.3-1.2-1.1-1.2-1.1-1.01.0-1.1-0.2-1.1-1.7
Conditioned reinforcement - inactives0.70.83.11.00.7-0.70.90.9-0.90.80.9-0.90.61.10.50.80.80.5-0.50.91.80.8-0.6
Conditioned locomotion4.45.36.3-2.5-2.42.4-2.3-2.42.4-2.2-2.42.4-2.5-2.2-2.1-2.3-2.1-2.52.5-2.3-1.2-2.3-2.1
Intermittent access intake day 1-15 change2.22.22.6-1.5-1.51.5-1.4-1.61.6-1.4-1.61.6-1.6-1.2-1.5-1.5-1.3-1.51.5-1.5-1.1-1.5-1.4
Intermittent access intake escalation2.32.32.6-1.6-1.61.6-1.4-1.61.6-1.5-1.61.6-1.6-1.2-1.5-1.5-1.4-1.51.5-1.6-1.2-1.5-1.5
Intermittent access intake escalation 21.71.72.0-1.3-1.41.4-1.2-1.31.3-1.3-1.41.4-1.3-1.0-1.3-1.3-1.1-1.31.3-1.4-1.4-1.3-1.2
Intermitt. access day 1 inactive lever presses0.40.41.90.80.5-0.50.60.7-0.70.60.6-0.60.50.70.30.60.60.6-0.60.71.40.6-0.7
Intermitt. access day 15 inactive lever presses0.50.65.8-0.2-0.70.7-0.5-0.40.3-0.5-0.30.3-0.7-0.5-0.7-0.4-0.8-0.60.6-0.40.6-0.5-2.4
Intermitt. access escalation Index2.72.43.8-1.7-1.41.4-1.7-1.61.6-1.6-1.61.5-1.4-1.8-1.4-1.7-1.5-1.41.4-1.6-1.9-1.5-0.8
Intermittent access day 1 total infusions0.20.30.60.40.5-0.50.30.5-0.50.30.5-0.50.50.30.60.40.40.8-0.80.50.70.50.3
Intermittent access day 15 total infusions0.20.30.7-0.6-0.50.5-0.6-0.50.5-0.6-0.50.5-0.6-0.4-0.4-0.5-0.5-0.30.3-0.5-0.0-0.5-0.9
Intermittent access terminal intake (last 3 days)0.20.31.6-0.4-0.50.5-0.5-0.40.4-0.5-0.40.4-0.5-0.4-0.4-0.5-0.5-0.30.3-0.4-0.1-0.5-1.2
Intermittent access total infusions0.00.00.1-0.2-0.10.1-0.2-0.10.1-0.2-0.10.1-0.1-0.2-0.0-0.2-0.10.0-0.0-0.10.1-0.1-0.3
Intermittent access day 1 locomotion0.20.20.70.40.4-0.40.30.4-0.40.30.4-0.40.30.40.40.40.40.4-0.40.50.80.4-0.2
Intermittent access day 15 total locomotion0.40.41.1-0.5-0.60.6-0.6-0.60.6-0.6-0.60.6-0.6-0.6-0.7-0.6-0.7-0.60.6-0.5-0.0-0.6-1.0
Intermittent access total locomotion0.70.81.4-0.9-0.90.9-0.9-0.90.9-0.9-0.90.9-1.0-0.9-0.9-0.9-0.8-0.90.9-0.8-0.2-0.9-1.2
Intermittent access standard deviation1.71.82.4-1.3-1.31.3-1.3-1.41.4-1.5-1.41.4-1.4-1.0-1.5-1.3-1.3-1.61.6-1.4-0.9-1.5-1.2
Cocaine induced anxiety0.10.11.2-0.2-0.20.2-0.2-0.20.2-0.3-0.20.2-0.1-0.0-0.1-0.2-0.2-0.40.4-0.4-1.1-0.3-0.1
Post-drug Anxiety0.50.60.91.00.6-0.60.80.8-0.80.70.9-0.90.70.90.80.80.80.7-0.70.70.60.7-0.3
Baseline Anxiety0.20.21.70.4-0.00.10.20.3-0.30.20.3-0.3-0.00.2-0.00.20.20.3-0.30.31.30.2-0.9
Lifetime Intake0.00.00.20.00.1-0.0-0.10.1-0.1-0.00.1-0.10.0-0.00.10.00.00.2-0.20.10.20.0-0.4
Incentive Sensitization - Responses0.10.10.4-0.1-0.20.2-0.1-0.20.1-0.2-0.20.2-0.3-0.1-0.3-0.1-0.2-0.20.2-0.10.5-0.2-0.6
Incentive Sensitization - Breakpoint0.20.20.5-0.4-0.40.4-0.4-0.40.4-0.4-0.40.4-0.5-0.3-0.5-0.3-0.4-0.50.5-0.30.3-0.4-0.7
Progressive ratio test 1 active lever presses0.10.10.50.00.3-0.30.10.2-0.20.20.2-0.20.2-0.00.40.20.30.4-0.40.30.70.20.2
Progressive ratio test 1 breakpoint0.30.31.00.30.6-0.60.30.4-0.40.40.4-0.40.40.20.60.40.50.7-0.70.61.00.50.4
Progressive ratio test 1 inactive lever presses0.10.10.7-0.2-0.20.2-0.3-0.20.2-0.3-0.20.2-0.3-0.3-0.3-0.2-0.2-0.20.2-0.10.7-0.2-0.9
Progressive ratio test 2 active lever presses0.10.10.60.20.1-0.10.10.2-0.20.10.2-0.20.10.10.20.20.10.3-0.30.30.80.2-0.6
Progressive ratio test 2 breakpoint0.00.00.50.00.0-0.0-0.00.1-0.10.00.1-0.1-0.0-0.00.10.10.00.2-0.20.20.70.1-0.5
Progressive ratio test 2 inactive lever presses0.10.20.70.50.2-0.20.30.4-0.40.30.4-0.40.30.40.20.30.30.3-0.30.30.50.3-0.8
Total sessions with >9 infusions0.40.50.8-0.8-0.60.6-0.8-0.70.7-0.8-0.80.8-0.7-0.9-0.7-0.8-0.7-0.40.4-0.6-0.0-0.7-0.9
Short access day 1 total inactive lever presses3.64.18.32.31.9-1.92.02.1-2.22.02.1-2.11.92.11.72.11.91.8-1.82.22.92.0-0.0
Short access day 10 total inactive lever presses0.90.91.51.20.8-0.81.11.1-1.11.01.1-1.11.01.10.81.10.80.9-0.91.00.71.0-0.2
Short access day 1 total infusions0.00.00.60.10.0-0.00.00.1-0.10.00.1-0.10.10.10.00.00.00.2-0.20.10.30.1-0.8
Short access day 10 total infusions0.30.40.5-0.6-0.60.6-0.7-0.60.6-0.7-0.60.6-0.6-0.7-0.6-0.6-0.7-0.50.5-0.6-0.3-0.7-0.5
Short access total infusions0.00.00.1-0.1-0.10.1-0.2-0.10.1-0.2-0.10.1-0.1-0.2-0.1-0.2-0.1-0.10.1-0.1-0.0-0.1-0.3
Short access day 1 locomotion0.80.91.4-0.9-0.90.9-0.9-0.90.9-1.0-1.01.0-1.0-0.7-1.1-0.9-0.8-1.11.1-0.80.1-1.0-1.2
Short access day 10 total locomotion0.50.51.3-0.7-0.70.6-0.5-0.70.7-0.6-0.80.8-0.8-0.6-0.8-0.6-0.5-1.11.1-0.60.2-0.7-0.6
Short access total locomotion0.90.91.6-1.0-0.90.9-0.8-1.01.0-1.0-1.01.0-1.0-0.8-1.1-0.9-0.8-1.31.3-0.9-0.2-1.0-0.8
Compulsive drug intake7.47.48.82.72.8-2.82.72.8-2.82.82.8-2.82.82.52.72.72.63.0-3.02.82.42.92.0
One hour access (0.3 mA shock)0.60.70.90.90.8-0.80.80.8-0.80.90.9-0.90.80.80.90.80.70.9-0.90.90.90.90.1
One hour access (shock baseline)2.42.83.2-1.7-1.71.7-1.7-1.71.7-1.7-1.71.7-1.8-1.5-1.7-1.7-1.7-1.81.8-1.7-1.1-1.8-1.5
Number of responses in last shaping day0.10.11.2-0.0-0.20.2-0.2-0.10.1-0.20.00.0-0.1-0.1-0.0-0.1-0.2-0.10.1-0.1-0.3-0.2-1.1
Context. condit. distance diff. score0.20.30.8-0.5-0.50.5-0.7-0.50.5-0.6-0.50.5-0.4-0.7-0.5-0.5-0.7-0.30.3-0.6-0.9-0.60.0
Locomotion velocity, session 10.50.61.6-0.7-0.80.8-0.7-0.80.8-0.4-0.70.7-0.7-0.9-0.7-0.7-0.8-0.80.8-0.8-1.3-0.6-0.5
Locomotion distance, session 12.33.04.01.71.8-1.81.91.7-1.71.81.7-1.71.91.91.91.82.01.6-1.61.60.31.82.0
Locomotion velocity, session 20.81.03.40.81.1-1.11.00.9-0.91.10.8-0.81.10.91.01.01.00.8-0.80.90.31.01.8
Locomotion distance, session 22.84.04.91.92.1-2.12.12.0-2.02.11.9-1.92.12.12.12.12.21.9-1.91.91.12.02.2
Locomotion velocity, session 30.00.10.40.10.2-0.20.30.1-0.10.20.1-0.10.20.30.20.20.40.1-0.10.1-0.00.20.6
Locomotion distance, session 33.23.44.01.72.0-2.01.91.8-1.81.91.8-1.81.91.81.91.92.02.0-2.01.81.11.92.0
Stereotopy head waving bouts, day 34.35.16.3-2.3-2.32.3-2.3-2.32.3-2.3-2.32.3-2.4-2.4-2.5-2.3-2.4-2.32.3-2.1-0.8-2.3-2.1
Stereotopy head waving duration, day 33.13.84.5-2.0-1.91.9-1.9-2.02.0-1.9-2.02.0-2.0-2.1-2.1-2.0-2.0-2.12.1-1.9-1.1-2.0-1.4
Locomotion velocity, session 71.51.72.11.21.4-1.41.41.3-1.31.31.2-1.21.31.51.31.31.51.2-1.21.30.81.31.4
Locomotion distance, session 75.06.47.32.42.7-2.72.52.5-2.52.52.4-2.42.62.52.52.52.62.6-2.62.62.12.62.4
Stereotopy head waving bouts, day 70.60.61.0-0.7-0.90.9-0.7-0.80.8-0.7-0.70.7-0.9-0.8-0.9-0.8-0.8-0.90.9-0.8-0.2-0.8-1.0
Stereotopy head waving duration, day 70.20.30.9-0.4-0.60.6-0.4-0.50.5-0.4-0.40.4-0.6-0.5-0.6-0.5-0.5-0.70.7-0.5-0.3-0.4-1.0
Locomotion velocity, session 80.20.23.4-0.3-0.30.3-0.2-0.30.3-0.2-0.20.2-0.1-0.3-0.1-0.3-0.3-0.30.3-0.5-1.8-0.30.5
Locomotion distance, session 80.60.92.30.81.0-1.00.90.9-0.90.80.9-0.91.10.91.00.91.00.9-0.90.8-0.20.91.5
Degree of sensitization distance0.00.00.10.10.1-0.10.10.1-0.10.10.1-0.10.10.20.10.10.1-0.00.00.1-0.10.10.3
Degree of sensitization stereotypy0.10.10.70.40.1-0.10.30.3-0.30.30.3-0.30.10.20.10.20.20.2-0.20.30.80.3-0.7
Condit. Reinf. active minus inactive responses0.10.10.50.30.3-0.30.20.3-0.30.30.3-0.30.30.20.30.30.20.4-0.40.40.70.3-0.2
Condit. Reinf. active-inactive response ratio0.20.20.5-0.4-0.50.5-0.4-0.50.4-0.3-0.50.5-0.5-0.6-0.5-0.4-0.6-0.50.5-0.40.2-0.4-0.7
Condit. Reinf. active responses0.10.10.50.30.2-0.20.10.3-0.30.20.3-0.30.20.10.20.30.10.4-0.40.30.70.2-0.5
Condit. Reinf. inactive responses0.30.40.80.60.5-0.50.50.6-0.60.50.6-0.60.50.40.50.50.50.9-0.90.70.90.6-0.3
Incentive salience index mean0.30.31.50.60.5-0.50.50.5-0.60.60.6-0.50.40.50.50.60.50.6-0.60.61.20.5-0.3
Condit. Reinf. lever presses0.91.22.71.11.0-0.91.21.1-1.11.21.1-1.10.91.11.11.21.11.1-1.11.11.71.1-0.4
Time in familiar zone, hab. session 10.60.61.40.90.6-0.50.60.8-0.80.70.9-0.90.60.50.60.70.50.9-0.90.81.20.7-0.8
Time in novel zone, hab. session 13.02.93.5-1.8-1.71.7-1.7-1.81.8-1.8-1.81.8-1.8-1.6-1.8-1.7-1.6-1.91.9-1.7-1.1-1.8-0.9
Total zone transitions, hab. session 16.18.79.83.03.0-3.03.13.0-3.03.03.1-3.13.13.03.13.13.13.0-3.02.91.63.02.2
Total locomotion distance, hab. session 12.53.63.92.01.9-1.91.92.0-2.01.92.0-2.01.91.91.92.02.02.0-2.02.01.71.91.0
Locomotion velocity, hab. session 13.34.85.32.22.3-2.32.32.2-2.22.22.2-2.22.32.22.22.32.32.2-2.22.21.52.21.7
Time in familiar zone, hab. session 20.30.41.8-0.4-0.70.7-0.5-0.50.5-0.4-0.50.5-0.7-0.5-0.6-0.5-0.6-0.50.5-0.50.1-0.5-1.3
Time in novel zone, hab. session 20.10.10.50.10.3-0.30.10.2-0.20.00.1-0.10.20.20.20.20.20.2-0.20.20.20.10.7
Total zone transitions, hab. session 21.62.12.41.51.4-1.41.41.5-1.51.51.6-1.61.51.51.51.51.51.5-1.51.40.81.50.8
Total locomotion distance, hab. session 20.00.00.00.10.1-0.10.10.1-0.10.10.1-0.10.10.10.10.10.20.1-0.10.10.00.1-0.0
Locomotion velocity, hab. session 20.00.00.10.10.2-0.20.20.2-0.20.20.2-0.20.20.10.20.20.20.2-0.20.2-0.10.20.3
Novel to familiar place preference ratio0.91.03.50.81.1-1.10.80.9-0.90.80.9-0.91.10.91.00.90.91.0-1.00.90.00.91.9
Novelty place preference1.11.13.60.91.2-1.20.81.0-1.00.91.0-1.01.20.91.11.00.91.1-1.11.00.30.91.9
Time in novel zone, NPP test0.80.92.50.81.0-1.00.70.9-0.90.80.9-0.91.00.81.00.90.81.0-1.00.90.50.81.6
Total zone transitions, NPP test3.34.86.12.22.2-2.22.42.2-2.22.32.2-2.22.22.42.32.32.52.0-2.02.21.62.31.4
Total locomotion distance, NPP test0.81.11.81.11.0-1.01.21.1-1.11.11.0-1.01.01.31.11.11.30.9-0.91.11.01.10.4
Locomotion velocity, NPP test1.31.82.61.31.4-1.41.51.3-1.31.41.3-1.31.41.61.41.41.61.2-1.21.30.91.41.0
Pavlov. Cond. lever latency1.52.05.5-1.5-1.21.2-1.5-1.41.4-1.5-1.41.4-1.1-1.5-1.3-1.5-1.4-1.21.2-1.5-2.3-1.40.1
Pavlov. Cond. magazine entry latency0.20.34.00.0-0.00.0-0.10.0-0.1-0.0-0.00.0-0.3-0.1-0.20.0-0.00.1-0.10.32.0-0.0-0.9
Pavlov. Cond. change in total contacts2.22.47.91.61.4-1.41.51.5-1.61.61.5-1.51.31.31.31.51.41.6-1.61.72.81.5-0.2
Pavlov. Cond. index score0.60.86.20.80.6-0.60.80.8-0.80.80.8-0.70.40.80.60.80.70.7-0.71.02.50.8-0.8
Pavlov. Cond. latency score0.70.95.50.90.7-0.70.90.8-0.90.90.8-0.80.60.90.70.90.90.8-0.81.02.30.8-0.5
Pavlov. Cond. lever contacts1.92.35.31.61.3-1.31.61.5-1.51.61.5-1.51.31.61.41.61.51.4-1.41.62.31.5-0.1
Pavlov. Cond. magazine entry number0.40.56.3-0.5-0.20.2-0.4-0.40.5-0.5-0.40.4-0.1-0.3-0.2-0.4-0.3-0.40.4-0.7-2.5-0.41.2
Pavlov. Cond. intertrial magazine entries0.50.61.00.80.8-0.80.80.8-0.80.70.8-0.80.90.60.80.70.71.0-1.00.7-0.10.80.8
Pavlov. Cond. lever-magazine prob. diff.0.60.86.30.70.6-0.60.70.7-0.70.70.7-0.70.40.70.50.70.70.6-0.60.92.50.7-0.8
Pavlov. Cond. response bias0.70.96.50.80.6-0.60.80.8-0.80.80.8-0.80.40.70.60.80.70.8-0.81.02.60.8-0.9
Bone: apparent density1.52.43.1-1.6-1.51.5-1.7-1.61.5-1.7-1.61.6-1.7-1.7-1.7-1.6-1.7-1.61.6-1.4-0.5-1.6-1.2
Bone surface0.30.60.8-0.8-0.60.6-0.9-0.70.8-0.9-0.80.8-0.7-0.9-0.9-0.8-0.8-0.80.8-0.8-0.9-0.90.2
Bone volume1.21.92.4-1.5-1.31.3-1.5-1.41.4-1.5-1.51.5-1.4-1.5-1.5-1.4-1.5-1.51.5-1.4-1.2-1.5-0.4
Bone: connectivity density0.10.20.5-0.3-0.40.4-0.5-0.30.3-0.5-0.40.4-0.5-0.5-0.6-0.4-0.5-0.40.4-0.20.7-0.5-0.7
Bone: cortical apparent density6.68.514.73.12.8-2.72.83.0-3.13.03.1-3.12.72.82.93.02.73.0-3.03.13.83.00.1
Bone: cortical area0.00.10.2-0.3-0.10.1-0.2-0.20.3-0.2-0.30.3-0.2-0.4-0.3-0.2-0.2-0.20.2-0.2-0.0-0.20.4
Bone: cortical porosity0.40.50.7-0.8-0.70.7-0.7-0.70.7-0.7-0.80.8-0.8-0.7-0.8-0.8-0.6-0.70.7-0.7-0.0-0.7-0.4
Bone: cortical porosity0.30.40.6-0.7-0.60.6-0.6-0.70.7-0.6-0.80.8-0.7-0.6-0.7-0.7-0.4-0.60.6-0.50.2-0.6-0.2
Bone: cortical thickness0.30.41.50.50.7-0.70.70.6-0.60.70.5-0.50.50.50.50.60.60.6-0.60.71.20.60.6
Bone: cortical thickness1.21.45.20.91.3-1.31.11.1-1.11.10.9-0.91.00.90.91.11.21.1-1.11.32.31.11.4
Bone: cortical tissue density6.98.915.23.22.8-2.82.93.1-3.13.13.2-3.22.82.83.03.12.73.1-3.13.23.93.00.1
Bone: elastic displacement0.20.20.3-0.5-0.40.4-0.4-0.50.5-0.3-0.50.5-0.5-0.4-0.4-0.4-0.4-0.60.6-0.4-0.2-0.4-0.3
Bone: elastic work0.00.00.3-0.3-0.0-0.0-0.2-0.20.2-0.1-0.30.3-0.1-0.2-0.1-0.1-0.0-0.10.1-0.1-0.2-0.10.5
Bone: endosteal estimation0.41.03.5-1.0-0.70.7-1.0-0.91.0-1.0-1.01.0-0.7-1.0-0.9-1.0-0.9-0.80.8-1.0-1.9-0.91.0
Bone: endosteal perimeter0.51.13.5-1.1-0.90.9-1.1-1.01.1-1.1-1.11.0-0.8-1.1-1.0-1.1-1.0-1.01.0-1.1-1.9-1.10.3
Bone: final force0.20.30.5-0.7-0.50.5-0.6-0.60.6-0.6-0.70.7-0.7-0.7-0.7-0.6-0.5-0.50.5-0.50.2-0.60.1
Bone: final moment0.30.40.7-0.8-0.50.5-0.7-0.70.7-0.6-0.80.8-0.7-0.8-0.8-0.7-0.6-0.60.6-0.60.1-0.70.2
Bone: marrow area0.30.72.9-0.9-0.60.5-0.8-0.80.8-0.8-0.80.8-0.5-0.8-0.7-0.8-0.7-0.70.7-0.9-1.7-0.81.0
Bone: maximum diameter0.50.81.2-1.0-0.80.8-0.9-0.90.9-0.9-1.01.0-0.9-1.0-1.1-1.0-0.9-0.90.9-0.9-0.8-0.9-0.1
Bone: maximum force0.61.01.6-1.2-0.80.8-1.1-1.11.1-1.1-1.21.2-1.0-1.2-1.1-1.1-1.0-0.90.9-1.0-0.8-1.00.4
Bone: maximum moment0.61.11.7-1.3-0.80.8-1.1-1.11.1-1.1-1.31.3-1.0-1.3-1.1-1.1-1.0-0.90.9-1.0-0.9-1.10.6
Bone: minimum diameter0.10.21.3-0.4-0.10.0-0.3-0.30.3-0.3-0.40.4-0.1-0.4-0.3-0.3-0.2-0.20.2-0.3-0.8-0.31.2
Bone: periosteal estimation0.40.91.3-1.0-0.70.7-1.0-0.91.0-0.9-1.01.0-0.8-1.1-1.0-0.9-0.9-0.90.9-0.9-1.1-0.90.5
Bone: periosteal perimeter0.40.61.4-0.8-0.60.6-0.7-0.80.8-0.8-0.80.8-0.6-0.8-0.8-0.8-0.8-0.80.8-0.8-1.2-0.80.5
Bone: post-yield work0.20.31.0-0.5-0.30.3-0.6-0.40.5-0.6-0.50.5-0.3-0.8-0.4-0.5-0.6-0.20.2-0.5-1.0-0.50.6
Bone: stiffness0.10.10.6-0.4-0.10.1-0.4-0.30.3-0.4-0.40.4-0.3-0.5-0.4-0.3-0.3-0.10.1-0.3-0.2-0.30.8
Bone: tissue strength0.10.10.6-0.3-0.40.4-0.4-0.40.4-0.3-0.30.3-0.3-0.5-0.3-0.3-0.5-0.20.2-0.4-0.7-0.3-0.2
Bone: trabecular number0.71.12.3-0.9-1.01.0-1.0-0.90.9-1.0-1.01.0-1.2-1.0-1.2-0.9-1.1-1.01.0-0.80.6-1.0-1.5
Bone: trabecular spacing0.00.10.20.20.0-0.00.30.1-0.10.30.2-0.20.20.40.30.20.30.1-0.10.1-0.30.2-0.3
Bone: trabecular thickness1.51.92.4-1.5-1.21.2-1.4-1.41.4-1.3-1.51.5-1.3-1.5-1.5-1.4-1.4-1.51.5-1.4-1.2-1.40.1
Bone: trabecular tissue density0.10.20.40.40.4-0.40.50.4-0.40.60.4-0.40.40.60.40.50.50.2-0.20.40.50.40.2
Breakpoint value in progressive ratio session4.45.06.12.32.3-2.32.32.3-2.32.52.3-2.32.42.22.22.32.12.1-2.12.21.52.31.9
Distance traveled before self-admin0.50.61.00.70.8-0.80.80.7-0.70.80.7-0.70.71.00.90.80.90.6-0.60.80.70.70.7
Distance traveled after self-admin1.41.53.5-1.4-1.21.2-1.2-1.31.3-1.2-1.31.3-1.1-1.2-1.0-1.4-1.1-0.90.9-1.3-1.9-1.1-0.0
Delta time in closed arm before/after self-admin0.10.11.00.10.1-0.10.10.1-0.10.20.2-0.20.3-0.00.3-0.00.10.4-0.40.0-1.00.30.1
Delta time in open arm before/after self-admin0.20.20.50.60.4-0.40.50.5-0.50.30.5-0.50.40.70.40.50.50.4-0.40.50.60.4-0.6
Diff in mean of infusions in LGA sessions0.70.71.31.00.7-0.71.00.9-0.91.11.0-1.00.80.70.60.70.71.0-1.00.90.81.00.2
Extinction: sum of active levers before priming0.90.92.00.81.0-1.00.80.9-0.90.91.0-1.01.10.91.11.01.01.0-1.00.90.31.01.4
Active lever presses in extinction session 60.10.10.3-0.4-0.40.4-0.4-0.40.4-0.3-0.40.4-0.4-0.3-0.4-0.3-0.6-0.40.4-0.4-0.2-0.4-0.5
Delta distance traveled before/after self-admin2.83.05.3-1.9-1.81.8-1.8-1.81.8-1.8-1.71.7-1.7-1.9-1.5-1.9-1.7-1.31.3-1.9-2.3-1.6-0.7
Delta ambulatory time before/after self-admin2.93.24.3-2.0-1.81.8-1.9-1.91.9-1.9-1.81.8-1.8-1.9-1.7-1.9-1.8-1.41.4-1.9-2.1-1.7-0.7
Time in closed arm before self-admin0.80.91.7-0.8-1.01.0-0.7-0.90.9-0.8-1.01.0-1.1-0.5-1.1-0.8-0.8-1.31.3-0.9-0.1-1.0-0.8
Time in closed arm after self-admin0.40.41.1-0.7-0.60.6-0.5-0.70.7-0.5-0.70.7-0.6-0.5-0.7-0.7-0.5-0.70.7-0.7-1.1-0.6-0.2
Time in open arm before self-admin0.20.20.80.20.2-0.20.20.3-0.20.30.4-0.40.4-0.10.60.10.20.7-0.70.2-0.90.40.3
Time in open arm after self-admin0.40.50.80.70.5-0.40.60.7-0.70.60.8-0.80.60.60.90.70.60.9-0.90.60.20.7-0.6
Sum of active levers in priming session hrs 5-63.53.54.61.91.9-1.92.01.9-1.92.11.9-1.91.81.91.81.81.81.7-1.71.92.02.01.3
Time to tail flick, vehicle, before self-admin1.91.92.51.61.4-1.41.31.5-1.51.41.6-1.61.41.21.31.41.11.4-1.41.51.41.30.5
Time to tail flick, vehicle, after self-admin0.10.10.6-0.2-0.40.4-0.4-0.30.3-0.4-0.30.3-0.4-0.2-0.4-0.4-0.4-0.20.2-0.3-0.2-0.3-0.8
Time to tail flick, test, before self-admin0.10.10.20.0-0.10.1-0.1-0.10.1-0.2-0.00.0-0.0-0.0-0.2-0.1-0.3-0.50.5-0.2-0.5-0.3-0.1
Time to tail flick, test, after self-admin0.10.10.3-0.5-0.20.2-0.5-0.40.4-0.4-0.40.4-0.3-0.6-0.3-0.4-0.5-0.20.2-0.3-0.4-0.30.2
Delta time to tail flick, vehicle, before/after SA1.41.31.6-1.2-1.21.2-1.2-1.21.2-1.2-1.31.3-1.2-1.0-1.2-1.2-1.1-1.21.2-1.2-0.6-1.2-1.0
Delta time to tail flick, test, before/after SA0.20.20.60.10.4-0.40.30.2-0.20.40.1-0.10.30.20.30.20.50.5-0.50.40.80.40.7
Ambulatory time before self-admin0.30.30.70.50.6-0.60.60.5-0.50.60.5-0.50.50.90.70.60.70.4-0.40.50.30.60.7
Ambulatory time after self-admin1.92.15.9-1.7-1.41.3-1.4-1.61.6-1.5-1.61.6-1.3-1.4-1.1-1.6-1.2-1.11.1-1.6-2.4-1.30.5
Total heroin consumption1.62.02.51.61.3-1.31.31.5-1.51.51.6-1.61.41.31.41.41.11.5-1.51.51.41.50.4
Area under the delay curve0.30.41.30.30.7-0.70.50.5-0.50.50.3-0.30.50.60.40.50.80.5-0.50.61.00.51.2
Delay disc. indifference point, 0s delay1.21.32.61.11.1-1.11.21.1-1.11.21.0-1.01.01.31.01.01.31.1-1.11.21.61.11.1
Delay disc. indifference point, 16s delay0.30.30.6-0.7-0.40.4-0.6-0.60.6-0.7-0.70.7-0.6-0.7-0.6-0.5-0.5-0.50.5-0.5-0.1-0.60.3
Delay disc. indifference point, 2s delay0.40.51.80.40.7-0.70.80.5-0.50.80.3-0.30.40.80.40.60.90.4-0.40.71.40.61.2
Delay disc. indifference point, 24s delay0.40.41.30.40.7-0.70.40.5-0.50.40.5-0.50.60.40.60.60.50.7-0.70.60.40.51.2
Delay disc. indifference point, 4s delay4.04.27.51.72.3-2.32.01.9-1.92.01.7-1.72.02.11.91.92.32.0-2.02.12.12.02.7
Delay disc. indifference point, 8s delay0.10.10.70.20.4-0.40.10.3-0.30.20.2-0.20.20.20.20.20.40.4-0.40.40.90.20.4
Delay discount exponential model param0.40.52.0-0.4-0.80.8-0.5-0.50.5-0.5-0.40.4-0.6-0.6-0.5-0.6-0.8-0.60.6-0.7-0.9-0.6-1.4
Delay discount hyperbolic model param0.70.82.5-0.6-1.01.0-0.8-0.80.8-0.8-0.60.6-0.8-0.9-0.7-0.8-1.1-0.80.8-0.9-1.2-0.8-1.6
Fecal boli incidents, locomotor time 12.83.03.8-1.6-1.71.7-1.8-1.71.7-1.8-1.71.7-1.7-1.7-1.8-1.6-1.9-1.81.8-1.8-1.8-1.8-1.4
Change in fecal boli incidents, locomotor task2.42.32.71.41.6-1.61.51.5-1.51.51.5-1.51.51.51.61.41.61.6-1.61.61.51.61.4
Time >=10cm from walls, locomotor time 10.20.20.90.50.3-0.30.30.4-0.40.30.5-0.50.30.20.30.30.20.5-0.50.51.00.4-0.8
Bouts of movement, locomotor time 10.10.10.3-0.2-0.10.1-0.4-0.20.2-0.4-0.20.2-0.1-0.5-0.3-0.1-0.5-0.20.2-0.2-0.4-0.30.4
Total resting periods, locomotor time 10.20.20.4-0.4-0.20.2-0.5-0.40.4-0.6-0.40.4-0.3-0.6-0.4-0.2-0.6-0.30.3-0.4-0.7-0.50.5
Rest time, locomotor task time 10.20.20.4-0.5-0.40.4-0.6-0.50.5-0.7-0.60.6-0.5-0.5-0.6-0.4-0.6-0.40.4-0.4-0.4-0.5-0.2
Distance moved, locomotor task time 11.01.11.51.01.1-1.11.01.0-1.11.01.0-1.01.01.01.10.91.01.0-1.01.11.21.01.0
Vertical activity count, locomotor time 10.20.20.40.40.4-0.40.40.5-0.50.50.5-0.50.50.40.70.30.40.4-0.40.50.40.50.5
Time >=10cm from walls, locomotor time 20.60.62.30.80.8-0.80.80.8-0.80.80.8-0.70.70.60.70.70.70.8-0.80.91.50.80.4
Bouts of movement, locomotor time 20.10.10.2-0.3-0.30.3-0.4-0.30.3-0.4-0.30.3-0.4-0.4-0.4-0.2-0.4-0.30.3-0.30.0-0.4-0.1
Total resting periods, locomotor time 20.10.10.2-0.3-0.40.4-0.4-0.30.3-0.5-0.30.3-0.4-0.4-0.4-0.3-0.4-0.30.3-0.3-0.1-0.4-0.4
Rest time, locomotor task time 21.01.21.81.31.0-1.01.01.2-1.20.91.3-1.31.21.01.21.20.91.2-1.21.10.51.1-0.2
Distance moved, locomotor task time 20.20.22.5-0.00.5-0.50.30.2-0.10.40.0-0.10.30.30.40.20.50.1-0.10.30.10.31.6
Vertical activity count, locomotor time 20.20.21.7-0.6-0.10.0-0.3-0.40.4-0.2-0.50.5-0.3-0.3-0.1-0.4-0.1-0.40.4-0.3-0.3-0.31.3
Weight adjusted by age0.80.91.21.00.9-0.91.11.0-1.01.11.0-1.01.00.91.10.91.00.8-0.80.90.51.00.8
Seeking ratio, delayed vs. immediate footshock0.30.40.8-0.5-0.60.6-0.8-0.50.5-0.7-0.50.5-0.5-0.9-0.6-0.6-0.9-0.40.4-0.6-0.7-0.6-0.6
Locomotion in novel chamber0.81.03.20.91.0-1.00.91.0-1.01.10.9-0.90.90.90.80.90.91.1-1.11.11.81.00.6
Locomotion in novel chamber post-restriction1.72.04.4-1.4-1.61.6-1.5-1.41.4-1.4-1.31.4-1.5-1.3-1.3-1.4-1.3-1.31.3-1.4-1.0-1.4-2.1
Progressive ratio0.30.40.70.70.6-0.60.80.6-0.60.90.5-0.50.50.90.30.70.70.2-0.20.60.70.60.1
Food seeking constrained by brief footshock0.70.81.3-0.9-0.90.9-1.1-0.90.9-0.9-1.01.0-1.0-1.0-1.0-0.9-1.1-0.90.9-0.9-0.5-1.0-0.7
Seeking ratio, punishment vs. effort0.40.51.3-0.9-0.70.7-1.1-0.80.8-1.0-0.70.7-0.7-1.1-0.5-0.8-0.9-0.20.2-0.7-0.5-0.7-0.2
Run reversals in cocaine runway, females0.20.22.20.10.4-0.40.30.2-0.20.30.2-0.30.40.20.50.20.40.4-0.40.2-0.50.41.5
Run reversals in cocaine runway, males0.80.83.9-0.6-1.11.1-0.8-0.80.7-0.7-0.60.6-1.0-0.6-0.7-0.7-0.8-0.90.9-0.8-0.3-0.8-2.0
Latency to leave start box in cocaine runway2.42.76.0-1.6-1.61.6-1.5-1.61.6-1.6-1.61.6-1.5-1.6-1.6-1.6-1.6-1.61.6-1.8-2.4-1.6-1.0
Latency to leave start box in cocaine runway, F4.04.48.1-2.2-2.12.1-2.0-2.12.1-2.2-2.22.2-2.0-1.9-2.0-2.1-1.9-2.02.0-2.3-2.8-2.1-1.3
Latency to leave start box in cocaine runway, M0.60.61.3-0.6-0.70.7-0.8-0.70.7-0.7-0.70.7-0.6-1.0-0.9-0.7-1.1-0.70.7-0.8-0.9-0.8-0.4
Cd content in liver0.70.71.11.00.9-0.80.80.9-0.90.80.9-0.90.90.80.80.90.80.9-0.90.91.10.80.1
Co content in liver0.10.10.7-0.1-0.10.1-0.1-0.10.1-0.2-0.10.10.0-0.2-0.1-0.1-0.2-0.20.2-0.2-0.8-0.20.4
Cu content in liver1.82.23.01.61.4-1.41.51.6-1.61.51.6-1.61.61.51.51.51.41.7-1.71.40.71.60.8
Fe content in liver1.41.63.01.21.4-1.41.31.3-1.31.31.2-1.21.41.21.31.31.31.2-1.21.20.41.31.7
K content in liver0.10.10.2-0.4-0.30.3-0.3-0.40.4-0.3-0.40.4-0.4-0.4-0.5-0.4-0.3-0.40.4-0.3-0.2-0.30.2
Mg content in liver0.70.71.00.90.8-0.80.90.9-0.90.90.9-0.90.80.90.70.90.90.8-0.80.91.00.90.3
Mn content in liver2.32.63.41.81.5-1.51.61.7-1.71.71.8-1.81.61.71.61.71.51.6-1.61.71.81.70.1
Na content in liver0.90.91.7-0.8-1.11.1-0.9-0.90.9-0.8-0.90.9-1.0-0.8-1.0-0.9-1.0-1.11.1-1.0-0.6-1.0-1.3
Rb content in liver0.20.21.40.40.1-0.10.30.4-0.40.30.4-0.30.10.40.20.30.30.4-0.40.41.00.4-1.2
Se content in liver0.10.20.4-0.4-0.30.3-0.3-0.40.3-0.4-0.50.5-0.5-0.3-0.6-0.4-0.4-0.40.4-0.30.5-0.4-0.4
Sr content in liver1.91.72.91.21.4-1.41.31.2-1.21.31.2-1.31.31.31.41.31.41.2-1.21.30.91.31.7
Zn content in liver0.10.10.5-0.0-0.20.2-0.0-0.10.10.0-0.10.1-0.30.1-0.2-0.10.0-0.20.2-0.00.7-0.1-0.6