Fgd6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000054515 0.07 0.06 1.8e-03 0.01 0.02 0.04 0.04 1.9e-02 2.7e-03 1.4e-05 1.6e-05
2 BLA gene expression ENSRNOG00000054515 0.11 0.05 4.2e-07 0.13 0.12 0.11 0.12 2.7e-07 9.6e-07 1.8e-06 4.1e-07
3 Brain gene expression ENSRNOG00000054515 0.16 0.06 0.0e+00 0.23 0.22 0.21 0.21 8.6e-21 1.2e-19 2.7e-19 2.2e-19
4 Eye gene expression ENSRNOG00000054515 0.52 0.19 3.2e-03 0.13 0.16 0.04 0.14 5.7e-03 2.3e-03 8.8e-02 3.9e-03
5 Liver gene expression ENSRNOG00000054515 0.04 0.02 6.8e-04 0.02 0.02 0.02 0.02 2.0e-03 1.8e-03 2.7e-03 6.5e-03
6 NAcc gene expression ENSRNOG00000054515 0.2 0.09 1.3e-05 0.04 0.06 0.06 0.05 1.0e-03 5.8e-05 1.6e-05 1.2e-04
7 PL gene expression ENSRNOG00000054515 0.07 0.03 1.8e-06 0.09 0.09 0.09 0.1 3.9e-07 5.5e-07 2.7e-07 5.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.27.014.93.2-2.5-2.5-2.50.7-3.9-2.1
BMI without tail3.57.312.62.2-3.0-3.0-3.50.2-2.4-3.0
Body weight11.147.066.85.9-7.9-8.2-8.2-0.2-6.8-7.2
Epididymis fat weight3.78.618.74.3-2.9-2.6-2.8-0.8-3.4-2.5
Glucose0.10.20.70.8-0.10.00.00.5-0.7-0.0
Heart weight0.50.83.2-0.5-0.9-0.70.10.7-1.80.2
Left kidney weight3.510.016.83.1-3.6-3.6-3.3-0.3-4.1-2.7
Right kidney weight2.36.713.92.6-2.8-2.7-2.60.1-3.7-2.2
Tail length6.920.838.72.5-5.6-5.7-6.2-1.1-2.4-5.4
Length with tail11.240.967.24.6-7.7-8.0-8.2-1.8-4.8-6.9
Length without tail6.514.223.12.9-4.7-4.8-4.3-1.0-3.8-3.4
Liver weight, left0.71.11.51.1-1.1-1.2-1.1-0.9-1.1-0.9
Liver weight, right1.11.84.51.1-2.1-2.0-1.10.2-1.1-0.7
Parametrial fat weight0.10.20.8-0.20.20.30.90.2-0.10.7
Retroperitoneal fat weight2.99.512.53.5-3.5-3.4-3.2-2.2-3.1-2.4
Intraocular pressure1.01.43.9-0.32.01.91.1-0.10.30.8
Extensor digitorum longus weight0.20.81.9-0.1-0.7-0.8-0.51.2-1.4-0.7
Soleus weight0.31.05.50.5-0.4-0.5-0.10.5-2.3-0.6
Tibialis anterior weight0.20.61.4-1.20.60.50.91.0-0.70.6
Tibia length8.524.138.34.1-5.4-5.5-6.2-2.7-4.2-5.4
Number of licking bursts0.40.51.31.10.50.4-0.10.7-1.1-0.4
Food consumed during 24 hour testing period0.20.31.11.0-0.4-0.4-0.6-0.1-0.30.1
Times rat made contact with spout2.02.35.12.3-0.5-0.4-1.80.3-1.8-2.0
Mean time between licks in bursts0.50.71.7-0.4-1.2-1.3-0.9-0.5-0.2-0.4
Mean num. licks in bursts0.10.10.30.2-0.2-0.1-0.5-0.50.2-0.2
Std. dev. time between licks in bursts0.80.93.1-1.8-0.5-0.60.4-0.80.61.2
Water consumed over 24 hours0.60.71.70.9-0.6-0.6-0.81.3-0.6-0.9
Indifference point 0 sec0.20.31.0-0.70.50.40.30.41.00.3
Indifference point AUC0.40.51.30.50.90.7-0.11.1-0.6-0.2
Indifference point function ln k0.20.30.8-0.5-0.6-0.7-0.2-0.90.10.1
Indifference point function log k0.20.30.8-0.5-0.6-0.7-0.2-0.90.10.1
Delay discounting total patch changes 0 sec0.20.30.8-0.70.40.40.40.50.90.3
Delay discounting total patch changes 12 sec0.40.51.30.70.30.1-0.61.1-0.5-1.0
Delay discounting total patch changes 18 sec0.50.61.80.60.70.5-0.40.91.4-0.5
Delay discounting total patch changes 24 sec0.40.61.60.7-0.0-0.3-1.10.7-0.2-1.3
Delay discounting total patch changes 6 sec0.40.72.0-0.01.41.20.50.90.30.3
Delay discounting time to switch 0 sec0.20.30.8-0.1-0.6-0.60.00.50.9-0.2
Delay discounting water rate 0 sec1.21.93.11.4-0.8-0.6-1.7-1.5-1.4-1.8
Delay discounting water rate 12 sec2.33.56.42.2-1.6-1.6-2.10.9-1.6-2.5
Delay discounting water rate 18 sec0.70.93.71.60.10.2-0.10.3-1.9-0.2
Delay discounting water rate 24 sec4.46.09.72.2-2.7-2.7-2.9-1.8-1.2-3.1
Delay discounting water rate 6 sec5.88.513.13.3-3.0-2.9-3.3-0.8-2.4-3.6
Locomotor activity4.87.612.52.4-3.1-3.0-3.0-0.7-3.5-2.6
Locomotor testing distance2.33.86.71.7-2.1-2.0-2.0-1.0-2.6-1.8
Locomotor testing rearing0.40.61.5-0.2-0.8-0.8-0.8-1.2-0.5-0.8
Light reinforcement 11.32.47.82.8-0.3-0.1-0.7-0.4-2.8-0.7
Light reinforcement 20.60.71.50.70.91.10.91.2-0.30.5
Reaction time number correct0.30.42.10.80.20.3-0.10.1-1.5-0.3
Reaction time mean minus median0.91.23.1-1.60.90.71.20.10.21.8
Reaction time mean minus median AUC1.01.23.3-1.40.90.91.20.00.21.8
Reaction time num false alarms1.21.62.5-1.61.10.91.51.31.11.2
Reaction time num false alarms AUC1.52.13.2-1.81.21.01.81.41.11.5
Reaction time trials correct on left0.30.42.10.80.20.3-0.10.1-1.5-0.3
Reaction time trials on left0.30.42.00.60.30.4-0.00.1-1.4-0.3
Reaction time mean0.10.10.4-0.4-0.0-0.10.1-0.6-0.20.3
Reaction time mean AUC0.10.10.2-0.4-0.3-0.4-0.1-0.4-0.20.1
Median of all reaction times0.20.30.40.4-0.6-0.6-0.5-0.6-0.4-0.5
Reaction time omissions2.12.84.6-1.72.02.02.10.30.81.8
Reaction time false alarm rate1.52.23.7-1.91.10.81.61.11.91.5
Reaction time premature initiation rate0.50.72.91.4-0.2-0.10.10.2-1.7-0.2
Reaction time premature initiations0.91.35.81.7-0.2-0.1-0.20.3-2.4-0.5
Std. dev. reaction times1.01.43.1-1.81.10.81.4-0.10.31.7
Reaction time trials completed0.30.42.00.60.30.4-0.00.1-1.4-0.3
Reaction time trials AUC0.30.52.20.80.30.3-0.10.2-1.5-0.4
Social response proportion3.53.87.71.7-2.4-2.3-1.50.5-2.8-1.5
Social responses2.22.98.61.4-1.8-1.6-1.3-0.9-2.9-1.2
Social time2.02.69.81.9-0.9-0.5-0.61.3-3.1-1.2
Conditioned locomotion0.10.10.4-0.1-0.3-0.30.10.00.7-0.4
Cocaine response after cond. corrected0.60.62.3-1.5-0.2-0.2-0.50.60.9-0.9
Cocaine response after cond. not corrected0.40.51.9-1.40.0-0.1-0.6-0.10.6-0.9
Cocaine response before conditioning0.40.42.20.30.50.5-0.1-1.5-0.20.5
Saline control response0.40.51.11.0-0.5-0.6-0.90.7-0.5-0.4
Condit. Reinf. active minus inactive responses0.30.30.70.80.1-0.00.50.8-0.00.8
Condit. Reinf. active-inactive response ratio0.20.21.00.6-0.1-0.2-0.11.0-0.4-0.0
Condit. Reinf. active responses0.20.31.01.00.1-0.00.60.3-0.20.9
Condit. Reinf. inactive responses0.70.92.2-0.70.70.71.1-0.80.81.5
Condit. Reinf. lever presses0.70.92.61.1-1.0-1.00.21.6-0.40.4
Condit. Reinf. lever reinforcers received0.30.41.71.3-0.1-0.20.50.1-0.40.8
Pavlov. Cond. lever latency0.20.31.2-1.10.50.60.1-0.30.0-0.2
Pavlov. Cond. magazine entry latency0.40.51.10.8-0.0-0.1-1.0-1.00.6-0.7
Pavlov. Cond. change in total contacts1.72.44.11.5-1.7-1.9-2.0-1.3-0.2-1.5
Pavlov. Cond. index score0.81.02.11.5-0.8-0.9-1.3-0.80.5-1.0
Pavlov. Cond. latency score0.60.71.61.2-0.6-0.7-1.0-0.80.6-0.7
Pavlov. Cond. lever contacts0.70.92.81.7-0.9-1.0-0.50.9-0.7-0.4
Pavlov. Cond. magazine entry number1.01.33.7-1.90.50.61.31.3-0.11.1
Pavlov. Cond. intertrial magazine entries0.20.30.5-0.7-0.3-0.30.30.5-0.70.6
Pavlov. Cond. lever-magazine prob. diff.0.91.22.21.5-0.9-1.0-1.4-0.90.5-1.2
Pavlov. Cond. response bias0.81.13.21.8-1.1-1.1-1.00.3-0.6-0.9
Conditioned reinforcement - actives0.60.61.81.10.3-0.5-1.00.10.4-1.3
Conditioned reinforcement - inactives0.10.10.30.2-0.1-0.4-0.40.3-0.0-0.6
Conditioned locomotion1.11.32.51.4-0.8-1.3-1.6-0.2-0.4-1.4
Intermittent access intake day 1-15 change0.30.31.20.30.40.5-0.4-0.1-0.2-1.1
Intermittent access intake escalation0.30.31.30.40.50.7-0.40.20.1-1.1
Intermittent access intake escalation 20.40.41.1-0.40.71.10.1-0.40.6-0.3
Intermitt. access day 1 inactive lever presses2.32.44.1-1.81.20.62.01.91.21.7
Intermitt. access day 15 inactive lever presses0.50.62.6-0.5-0.0-0.01.0-0.1-0.51.6
Intermitt. access escalation Index0.80.71.5-0.51.11.00.9-0.40.31.2
Intermittent access day 1 total infusions2.93.35.81.8-1.8-2.2-2.4-1.0-0.6-2.2
Intermittent access day 15 total infusions2.73.17.02.1-1.2-1.3-2.4-0.9-0.8-2.6
Intermittent access terminal intake (last 3 days)3.13.36.51.8-1.5-1.7-2.6-1.4-0.7-2.5
Intermittent access total infusions3.43.77.52.0-1.5-2.0-2.7-1.1-0.4-2.7
Intermittent access day 1 locomotion1.71.73.11.2-1.3-1.8-1.6-0.3-0.3-1.7
Intermittent access day 15 total locomotion1.51.63.61.2-1.0-1.4-1.9-0.70.1-1.6
Intermittent access total locomotion1.92.14.21.1-1.3-1.8-2.0-0.7-0.1-2.0
Intermittent access standard deviation1.51.64.51.5-0.4-0.8-1.6-0.8-0.3-2.1
Cocaine induced anxiety0.91.02.4-0.81.00.91.00.31.21.6
Post-drug Anxiety0.50.62.0-0.70.50.40.9-0.00.51.4
Baseline Anxiety0.30.30.80.4-0.3-0.3-0.3-0.7-0.9-0.5
Lifetime Intake3.03.36.51.9-1.3-1.7-2.6-1.6-0.3-2.5
Incentive Sensitization - Responses1.11.12.40.9-1.1-1.1-1.6-0.60.1-1.4
Incentive Sensitization - Breakpoint0.90.92.00.7-1.0-0.9-1.4-0.60.2-1.2
Progressive ratio test 1 active lever presses7.07.215.93.1-2.2-2.5-3.5-0.6-1.3-4.0
Progressive ratio test 1 breakpoint6.87.014.63.1-2.2-2.5-3.3-0.7-1.6-3.8
Progressive ratio test 1 inactive lever presses0.30.30.80.5-0.3-0.9-0.50.2-0.7-0.6
Progressive ratio test 2 active lever presses2.82.95.71.9-1.3-1.7-2.3-1.0-0.4-2.4
Progressive ratio test 2 breakpoint3.13.46.92.0-1.5-1.9-2.5-0.9-0.5-2.6
Progressive ratio test 2 inactive lever presses0.40.50.91.0-0.4-0.7-0.8-0.1-0.7-0.8
Total sessions with >9 infusions2.52.75.32.0-1.1-1.4-2.1-1.3-0.7-2.3
Short access day 1 total inactive lever presses0.10.10.4-0.60.1-0.20.20.1-0.3-0.0
Short access day 10 total inactive lever presses2.42.78.5-2.40.30.42.00.1-0.02.9
Short access day 1 total infusions2.02.23.51.1-1.3-1.5-1.9-1.7-0.6-1.8
Short access day 10 total infusions4.34.78.12.2-2.3-2.5-2.9-0.6-0.8-2.7
Short access total infusions4.04.47.32.2-2.0-2.2-2.7-1.4-0.9-2.7
Short access day 1 locomotion2.83.04.11.6-2.0-1.9-1.8-0.4-1.8-2.0
Short access day 10 total locomotion0.40.41.3-0.6-0.2-1.00.10.11.1-0.4
Short access total locomotion1.71.84.01.2-1.2-1.8-1.40.2-0.5-2.0
Compulsive drug intake1.71.74.4-1.31.21.21.3-0.90.92.1
One hour access (0.3 mA shock)2.22.65.91.4-0.2-0.9-2.3-2.40.6-1.9
One hour access (shock baseline)2.93.47.41.8-1.1-1.8-2.5-1.4-0.5-2.7
Number of responses in last shaping day0.70.71.60.9-0.3-0.8-1.3-0.9-0.5-1.0
Context. condit. distance diff. score0.80.91.8-0.1-0.9-0.9-1.4-1.30.6-0.9
Locomotion velocity, session 10.40.41.20.00.50.51.0-0.3-0.21.1
Locomotion distance, session 10.30.41.40.7-0.4-0.40.1-0.8-1.20.1
Locomotion velocity, session 20.20.30.8-0.5-0.3-0.30.40.90.30.7
Locomotion distance, session 20.71.02.80.9-1.1-1.1-0.5-0.1-1.7-0.7
Locomotion velocity, session 30.60.72.90.5-0.7-0.6-0.1-0.7-1.70.4
Locomotion distance, session 31.01.12.21.1-1.2-1.1-0.9-0.9-1.5-0.6
Stereotopy head waving bouts, day 30.91.12.2-0.91.21.21.50.80.41.1
Stereotopy head waving duration, day 30.30.40.9-0.60.60.61.00.7-0.00.7
Locomotion velocity, session 70.60.61.31.0-1.2-1.2-0.6-0.4-0.3-0.3
Locomotion distance, session 70.20.30.50.7-0.7-0.7-0.4-0.4-0.5-0.3
Stereotopy head waving bouts, day 70.40.51.90.9-0.3-0.40.31.4-0.60.2
Stereotopy head waving duration, day 70.40.41.80.50.00.00.61.3-0.70.4
Locomotion velocity, session 80.50.61.4-0.5-1.2-1.2-0.9-0.40.2-0.3
Locomotion distance, session 83.04.56.91.3-2.5-2.5-2.6-2.0-1.4-2.1
Degree of sensitization distance0.20.20.3-0.50.50.40.50.60.50.4
Degree of sensitization stereotypy0.50.52.40.80.0-0.00.61.5-0.30.5
Condit. Reinf. active minus inactive responses1.31.52.6-0.71.51.51.4-0.60.81.6
Condit. Reinf. active-inactive response ratio1.01.11.5-0.91.11.21.20.21.01.2
Condit. Reinf. active responses2.53.04.9-1.02.22.22.20.10.92.2
Condit. Reinf. inactive responses1.61.93.7-0.81.71.61.90.70.41.7
Incentive salience index mean0.40.40.8-0.10.90.80.7-0.7-0.10.8
Condit. Reinf. lever presses0.10.10.60.4-0.1-0.2-0.1-0.4-0.8-0.1
Time in familiar zone, hab. session 10.10.10.50.2-0.0-0.00.30.3-0.70.3
Time in novel zone, hab. session 10.80.82.6-0.80.91.00.50.31.60.5
Total zone transitions, hab. session 12.63.74.82.0-2.1-2.2-2.0-0.9-2.2-1.7
Total locomotion distance, hab. session 13.14.58.32.8-2.0-2.0-1.9-1.2-2.9-1.5
Locomotion velocity, hab. session 14.15.910.93.2-2.2-2.2-2.2-1.7-3.3-1.7
Time in familiar zone, hab. session 20.10.10.20.1-0.4-0.5-0.00.3-0.50.2
Time in novel zone, hab. session 20.40.40.8-0.70.80.90.60.10.60.6
Total zone transitions, hab. session 20.81.02.20.9-1.0-1.0-0.6-1.3-1.5-0.2
Total locomotion distance, hab. session 20.81.02.61.4-0.6-0.7-0.5-1.2-1.6-0.2
Locomotion velocity, hab. session 20.91.12.51.4-0.7-0.7-0.5-1.6-1.5-0.3
Novel to familiar place preference ratio0.20.21.0-0.3-0.5-0.5-0.3-0.11.00.2
Novelty place preference0.30.31.3-0.5-0.3-0.30.00.11.10.6
Time in novel zone, NPP test0.20.20.9-0.4-0.5-0.5-0.10.20.90.5
Total zone transitions, NPP test1.11.62.90.6-1.6-1.6-1.0-1.1-1.7-0.7
Total locomotion distance, NPP test1.31.84.41.7-1.1-1.1-0.9-1.3-2.1-0.7
Locomotion velocity, NPP test0.91.32.71.5-0.7-0.7-0.7-1.5-1.7-0.5
Pavlov. Cond. lever latency0.40.51.00.0-1.0-0.9-1.0-0.30.1-0.6
Pavlov. Cond. magazine entry latency0.10.10.30.00.40.30.4-0.20.30.6
Pavlov. Cond. change in total contacts0.40.41.00.81.00.90.50.20.10.1
Pavlov. Cond. index score0.20.30.60.20.60.50.80.1-0.30.7
Pavlov. Cond. latency score0.30.30.70.30.70.60.80.1-0.60.7
Pavlov. Cond. lever contacts0.10.10.50.50.30.20.30.1-0.70.0
Pavlov. Cond. magazine entry number0.10.10.3-0.2-0.2-0.2-0.40.5-0.1-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.20.20.2-0.1-0.50.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.40.10.40.30.60.1-0.40.5
Pavlov. Cond. response bias0.10.10.30.50.40.30.3-0.2-0.00.1
Bone: apparent density0.20.31.60.00.10.20.11.3-0.5-0.5
Bone surface0.20.31.30.2-0.2-0.1-0.60.2-1.1-0.6
Bone volume0.30.61.70.3-0.6-0.5-0.70.8-1.3-0.8
Bone: connectivity density0.40.71.3-0.51.11.10.81.10.00.5
Bone: cortical apparent density0.60.81.20.8-1.1-1.1-0.9-1.10.3-0.5
Bone: cortical area1.62.44.80.3-1.6-1.6-1.7-0.5-2.2-1.9
Bone: cortical porosity0.60.71.9-1.4-0.8-0.8-0.01.3-0.0-0.2
Bone: cortical porosity0.70.81.4-1.2-1.2-1.2-0.30.9-0.3-0.5
Bone: cortical thickness0.91.42.2-0.6-1.5-1.5-1.2-0.1-1.2-1.5
Bone: cortical thickness0.50.51.5-1.20.30.31.00.9-0.30.6
Bone: cortical tissue density0.60.81.30.7-1.1-1.1-0.9-1.10.4-0.5
Bone: elastic displacement3.43.89.1-3.01.81.62.30.31.52.0
Bone: elastic work2.12.79.5-3.11.41.21.80.00.91.6
Bone: endosteal estimation0.10.30.50.70.60.70.10.4-0.6-0.2
Bone: endosteal perimeter1.02.04.31.0-0.9-1.0-1.9-1.4-1.2-2.1
Bone: final force0.60.92.70.3-0.9-0.8-0.70.6-1.6-1.2
Bone: final moment0.61.03.40.2-0.9-0.8-0.70.6-1.8-1.2
Bone: marrow area0.10.20.50.70.60.60.10.4-0.5-0.2
Bone: maximum diameter1.73.15.21.5-1.6-1.5-2.0-0.9-2.2-2.3
Bone: maximum force0.30.52.4-0.3-0.7-0.6-0.40.5-1.5-0.5
Bone: maximum moment0.40.63.1-0.4-0.6-0.5-0.30.4-1.8-0.5
Bone: minimum diameter3.46.29.32.1-2.4-2.3-3.0-1.1-3.1-2.8
Bone: periosteal estimation0.51.12.80.7-0.7-0.7-1.1-0.5-1.7-1.3
Bone: periosteal perimeter0.91.52.50.4-1.1-1.1-1.5-0.9-1.5-1.6
Bone: post-yield work0.50.72.11.3-0.2-0.1-0.40.8-1.4-0.5
Bone: stiffness2.23.56.61.5-2.1-2.0-1.51.1-2.6-1.7
Bone: tissue strength0.50.51.10.7-0.5-0.4-0.40.9-1.0-0.6
Bone: trabecular number0.40.71.6-0.41.21.30.80.80.10.3
Bone: trabecular spacing0.40.51.9-1.00.10.00.0-1.40.50.7
Bone: trabecular thickness0.91.11.91.1-1.0-0.9-0.61.3-1.4-0.8
Bone: trabecular tissue density0.20.20.60.7-0.2-0.3-0.1-0.50.7-0.1
Breakpoint value in progressive ratio session0.91.02.4-0.70.50.81.40.6-0.81.6
Distance traveled before self-admin0.70.71.91.0-0.1-0.2-0.4-1.1-1.4-0.8
Distance traveled after self-admin1.31.45.20.8-1.1-1.0-0.5-0.9-2.3-0.7
Delta time in closed arm before/after self-admin0.70.71.90.6-1.1-1.1-0.50.2-1.4-0.3
Delta time in open arm before/after self-admin1.51.43.1-1.40.10.41.21.81.31.2
Diff in mean of infusions in LGA sessions0.70.82.5-0.90.20.71.60.3-0.01.3
Extinction: sum of active levers before priming0.10.10.3-0.10.00.10.6-0.0-0.50.5
Active lever presses in extinction session 60.60.62.50.2-0.9-0.7-0.10.4-1.6-0.2
Delta distance traveled before/after self-admin0.30.31.00.2-0.8-0.50.00.4-1.0-0.2
Delta ambulatory time before/after self-admin0.20.20.6-0.5-0.20.10.70.80.00.4
Time in closed arm before self-admin0.30.30.90.60.1-0.3-0.8-0.9-0.5-0.2
Time in closed arm after self-admin0.90.92.31.3-0.5-0.9-0.90.4-1.5-0.9
Time in open arm before self-admin0.10.20.50.20.20.50.4-0.70.40.1
Time in open arm after self-admin1.01.12.8-1.5-0.10.11.00.81.71.1
Sum of active levers in priming session hrs 5-60.30.30.90.8-0.1-0.1-0.20.7-1.0-0.4
Time to tail flick, vehicle, before self-admin1.71.84.41.4-0.7-1.0-2.1-0.8-0.4-2.0
Time to tail flick, vehicle, after self-admin1.71.83.1-1.30.90.81.61.81.51.2
Time to tail flick, test, before self-admin0.20.10.70.8-0.1-0.0-0.2-0.4-0.3-0.2
Time to tail flick, test, after self-admin0.20.20.40.60.60.6-0.2-0.50.3-0.1
Delta time to tail flick, vehicle, before/after SA3.63.55.9-2.01.51.62.41.81.42.2
Delta time to tail flick, test, before/after SA0.20.20.4-0.30.60.60.00.20.60.4
Ambulatory time before self-admin0.80.92.61.2-0.4-0.5-0.5-0.5-1.6-1.1
Ambulatory time after self-admin1.81.95.81.0-1.6-1.4-0.6-1.2-2.4-0.9
Total heroin consumption0.40.41.0-0.40.20.50.7-0.7-1.00.7
Area under the delay curve0.60.62.8-1.7-0.1-0.3-0.3-0.80.6-0.4
Delay disc. indifference point, 0s delay0.20.20.8-0.20.2-0.10.50.9-0.10.4
Delay disc. indifference point, 16s delay0.50.50.7-0.8-0.6-0.6-0.5-0.7-0.8-0.8
Delay disc. indifference point, 2s delay0.70.81.90.4-1.0-1.1-1.0-1.4-0.1-0.8
Delay disc. indifference point, 24s delay1.51.44.3-0.9-0.8-0.8-1.1-2.1-1.0-1.1
Delay disc. indifference point, 4s delay0.50.62.5-1.6-0.0-0.20.0-0.11.2-0.2
Delay disc. indifference point, 8s delay1.01.05.7-2.40.20.30.10.21.0-0.0
Delay discount exponential model param0.70.72.81.70.30.40.50.9-0.70.6
Delay discount hyperbolic model param0.70.72.51.60.50.60.60.9-0.60.6
Fecal boli incidents, locomotor time 10.50.61.2-0.2-0.8-1.1-0.30.91.0-0.6
Change in fecal boli incidents, locomotor task0.90.91.60.21.31.10.6-1.30.31.1
Time >=10cm from walls, locomotor time 10.70.71.6-1.20.80.60.80.40.71.1
Bouts of movement, locomotor time 10.70.81.5-1.20.80.61.01.2-0.60.8
Total resting periods, locomotor time 10.80.91.7-1.30.90.61.10.9-0.51.1
Rest time, locomotor task time 11.51.73.0-1.01.71.11.70.9-0.21.7
Distance moved, locomotor task time 10.50.61.11.0-0.8-0.5-1.1-0.50.2-0.9
Vertical activity count, locomotor time 12.93.04.61.9-1.8-1.7-2.2-1.3-0.9-2.0
Time >=10cm from walls, locomotor time 21.01.02.7-0.81.40.90.70.71.70.4
Bouts of movement, locomotor time 20.40.41.8-1.4-0.7-0.6-0.3-0.60.2-0.1
Total resting periods, locomotor time 20.40.42.2-1.5-0.3-0.3-0.1-0.50.20.2
Rest time, locomotor task time 20.91.12.5-0.81.20.91.30.2-0.21.6
Distance moved, locomotor task time 20.40.41.21.1-0.6-0.3-0.60.6-0.1-0.8
Vertical activity count, locomotor time 24.85.38.02.4-2.6-2.6-2.41.3-1.5-2.8
Weight adjusted by age0.40.40.70.7-0.5-0.5-0.7-0.7-0.3-0.8
Seeking ratio, delayed vs. immediate footshock0.30.30.9-0.9-0.3-0.50.30.8-0.10.2
Locomotion in novel chamber0.50.73.00.1-0.6-0.7-0.6-1.7-0.5-0.3
Locomotion in novel chamber post-restriction0.10.10.40.2-0.4-0.1-0.4-0.3-0.4-0.6
Progressive ratio2.73.16.1-2.11.31.41.1-2.12.51.4
Food seeking constrained by brief footshock0.81.02.10.9-1.2-0.8-1.4-0.1-0.1-1.4
Seeking ratio, punishment vs. effort2.02.54.01.8-1.4-1.3-1.21.6-2.0-1.5
Run reversals in cocaine runway, females1.31.32.60.1-1.4-1.1-0.8-1.2-1.6-1.1
Run reversals in cocaine runway, males0.30.31.21.1-0.0-0.00.20.3-0.90.5
Latency to leave start box in cocaine runway0.40.52.20.6-0.1-0.4-0.6-0.3-1.50.1
Latency to leave start box in cocaine runway, F0.60.71.31.20.90.60.6-0.3-1.00.8
Latency to leave start box in cocaine runway, M1.81.83.9-0.1-1.5-1.6-2.00.0-1.5-1.1
Cd content in liver0.91.01.60.5-1.3-1.3-0.91.2-0.4-0.8
Co content in liver2.02.43.90.9-1.9-1.9-2.0-1.00.0-2.0
Cu content in liver1.01.21.61.3-1.2-1.2-0.71.2-1.2-1.0
Fe content in liver0.50.61.00.5-0.9-0.9-1.0-0.2-0.6-1.0
K content in liver0.70.72.9-0.70.10.10.61.01.70.4
Mg content in liver0.50.50.9-0.30.50.60.70.51.01.0
Mn content in liver0.00.00.10.1-0.10.00.10.10.30.0
Na content in liver0.30.31.5-0.0-0.2-0.2-0.10.61.2-0.2
Rb content in liver1.92.38.3-2.10.60.70.81.32.90.5
Se content in liver0.50.62.81.7-0.6-0.7-0.2-0.5-0.50.2
Sr content in liver0.30.31.6-0.0-0.2-0.3-0.00.5-1.2-0.3
Zn content in liver0.20.30.60.1-0.7-0.8-0.4-0.2-0.60.3