Best TWAS P=5.950202e-08 · Best GWAS P=3.390961e-08 conditioned to 3.057772e-90
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Cited2 | gene expression | ENSRNOG00000056940 | 0.1 | 0.07 | enet | 156 | 0.11 | 2.3e-12 | -5.2 | 5.4 | 6e-08 | -0.86 | 0.43 | 0.56 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.