Hub : Genes

ENSRNOG00000065364

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000065364	0.67	0.1	0.0e+00	0.66	0.68	0.69	0.69	7.4e-97	9.7e-103	7.1e-107	4.8e-107
2	BLA	gene expression	ENSRNOG00000065364	0.08	0.05	5.7e-03	0.04	0.02	0.01	0.03	5.8e-03	2.2e-02	6.5e-02	8.1e-03
3	LHb	gene expression	ENSRNOG00000065364	0.15	0.09	6.1e-03	0.01	0.03	0.02	0.01	2.1e-01	5.8e-02	1.3e-01	1.6e-01
4	Liver	gene expression	ENSRNOG00000065364	0.61	0.13	0.0e+00	0.24	0.18	0.26	0.25	6.0e-27	2.9e-19	4.8e-29	2.8e-27
5	NAcc	gene expression	ENSRNOG00000065364	0.06	0.04	3.7e-03	0	0.02	0.01	0.01	3.1e-01	2.3e-02	6.7e-02	8.3e-02
6	PL	gene expression	ENSRNOG00000065364	0.05	0.04	6.7e-03	-0	0.02	0	0	4.6e-01	1.8e-02	2.4e-01	2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	0.9	3.0	6.8	2.6	0.3	-1.9	2.3	-0.9	-1.4
BMI without tail	2.8	5.8	12.7	2.0	-0.2	-3.5	1.6	-3.6	-2.0
Body weight	3.0	12.9	17.0	3.9	-0.7	-3.9	4.1	-3.6	-4.1
Epididymis fat weight	3.3	7.8	16.1	4.0	3.2	-2.7	3.1	0.6	1.6
Glucose	3.6	5.5	17.2	-2.6	-4.1	2.1	-1.2	-0.4	-1.9
Heart weight	0.9	1.3	3.7	0.3	-0.6	-1.4	0.4	-1.9	-1.2
Left kidney weight	1.6	4.7	7.0	2.6	-0.3	-2.6	2.2	-2.3	-2.2
Right kidney weight	1.6	4.6	6.5	2.2	-1.1	-2.4	1.8	-2.4	-2.6
Tail length	3.2	9.7	28.5	0.4	-1.9	-3.2	1.0	-5.3	-3.8
Length with tail	1.9	6.9	14.1	1.2	-1.6	-2.6	2.1	-3.8	-3.5
Length without tail	0.9	2.0	4.2	1.4	-1.2	-0.7	1.9	-0.8	-2.0
Liver weight, left	0.7	1.1	3.2	0.9	-0.8	-0.7	0.9	-0.9	-1.8
Liver weight, right	1.7	2.8	7.3	-0.6	-1.7	-0.9	-0.5	-2.7	-2.3
Parametrial fat weight	0.5	1.0	3.0	1.7	0.9	-0.9	1.0	0.1	-0.1
Retroperitoneal fat weight	0.3	1.1	2.1	1.4	0.2	-1.1	1.5	-0.7	-0.8
Intraocular pressure	0.8	1.1	2.9	0.2	1.4	0.7	0.4	1.7	0.9
Extensor digitorum longus weight	0.2	1.0	3.5	-0.2	-1.9	0.3	-0.3	-0.4	-1.3
Soleus weight	2.0	5.7	14.8	-1.7	-3.8	1.1	-1.3	-1.7	-3.3
Tibialis anterior weight	0.1	0.4	0.9	0.6	0.7	-0.3	-0.3	0.6	1.0
Tibia length	2.1	6.0	14.2	1.3	-2.8	-1.6	1.1	-2.9	-3.8
Number of licking bursts	0.9	1.1	2.4	-1.5	-0.9	1.0	-1.4	-0.2	-0.3
Food consumed during 24 hour testing period	0.3	0.3	1.6	0.1	-0.2	0.3	0.1	-0.2	-1.3
Times rat made contact with spout	1.4	1.6	4.5	0.0	2.1	-0.2	-0.4	0.8	2.1
Mean time between licks in bursts	1.4	1.9	3.7	-1.8	-1.9	1.0	-1.3	-0.7	-1.2
Mean num. licks in bursts	1.5	1.8	4.3	1.6	2.1	-1.1	1.1	0.5	1.3
Std. dev. time between licks in bursts	1.8	2.1	4.2	-1.6	-2.0	0.7	-0.9	-1.3	-1.8
Water consumed over 24 hours	0.2	0.2	0.4	-0.6	-0.6	0.5	-0.2	-0.2	-0.3
Indifference point 0 sec	2.2	3.5	5.9	2.4	1.9	-2.2	2.4	-1.0	-0.3
Indifference point AUC	0.7	0.9	3.2	-0.1	0.2	-1.3	-0.5	-1.8	-0.3
Indifference point function ln k	0.5	0.6	1.7	-1.1	-1.3	0.6	-0.6	-0.2	-0.2
Indifference point function log k	0.5	0.6	1.7	-1.1	-1.3	0.6	-0.6	-0.2	-0.2
Delay discounting total patch changes 0 sec	2.4	3.8	6.4	2.5	1.9	-2.4	2.5	-1.0	-0.2
Delay discounting total patch changes 12 sec	1.4	1.9	3.6	1.8	1.5	-1.9	1.2	-0.9	0.1
Delay discounting total patch changes 18 sec	2.3	3.0	9.5	2.0	3.1	-1.1	1.2	0.9	1.3
Delay discounting total patch changes 24 sec	2.1	2.6	8.2	1.1	2.9	-0.3	0.8	1.4	1.9
Delay discounting total patch changes 6 sec	2.1	3.1	6.0	2.2	2.4	-2.0	2.0	-0.6	0.3
Delay discounting time to switch 0 sec	0.8	1.2	3.6	1.3	0.9	0.6	0.8	1.9	0.3
Delay discounting water rate 0 sec	0.2	0.3	0.6	0.1	0.3	-0.5	0.8	-0.8	-0.3
Delay discounting water rate 12 sec	0.3	0.5	1.4	-0.1	0.9	0.2	-0.4	0.7	1.2
Delay discounting water rate 18 sec	0.2	0.3	1.1	0.5	0.1	-0.6	1.1	-0.4	-0.2
Delay discounting water rate 24 sec	0.2	0.3	0.8	0.3	-0.9	-0.7	0.0	-0.5	0.2
Delay discounting water rate 6 sec	0.3	0.4	1.7	0.0	1.3	0.0	0.1	0.3	0.6
Locomotor activity	1.5	2.3	6.3	0.6	-0.7	-1.6	0.3	-2.5	-2.1
Locomotor testing distance	0.6	0.9	2.0	0.7	-0.4	-0.9	0.4	-1.4	-1.4
Locomotor testing rearing	0.7	1.0	3.1	1.0	-0.1	-0.7	0.8	-1.0	-1.8
Light reinforcement 1	0.2	0.4	0.9	0.8	0.9	0.3	-0.4	0.9	0.2
Light reinforcement 2	0.2	0.3	0.5	0.5	0.7	0.3	-0.1	0.3	-0.7
Reaction time number correct	1.1	1.6	3.4	1.8	1.2	-1.3	1.7	-0.1	-0.1
Reaction time mean minus median	1.3	1.7	3.5	-1.9	-1.1	1.5	-1.7	0.2	-0.3
Reaction time mean minus median AUC	1.2	1.5	3.3	-1.8	-1.1	1.6	-1.2	0.6	0.1
Reaction time num false alarms	0.4	0.5	1.6	-0.8	-0.5	0.0	-1.3	-0.8	-0.0
Reaction time num false alarms AUC	0.6	0.8	1.9	-0.8	-0.7	-0.4	-1.4	-1.4	-0.2
Reaction time trials correct on left	1.1	1.6	3.4	1.8	1.2	-1.3	1.7	-0.1	-0.1
Reaction time trials on left	1.1	1.6	3.3	1.8	1.1	-1.3	1.7	-0.2	-0.2
Reaction time mean	1.7	2.4	5.4	-2.0	-1.3	2.3	-1.3	0.9	-0.6
Reaction time mean AUC	1.5	2.1	4.9	-1.9	-1.2	2.2	-1.1	0.9	-0.6
Median of all reaction times	1.3	1.8	4.4	-1.6	-1.2	2.1	-0.8	1.0	-0.7
Reaction time omissions	1.1	1.5	2.7	-1.5	-1.6	1.5	-1.2	0.5	-0.4
Reaction time false alarm rate	1.3	1.9	4.5	-1.8	-1.4	0.4	-2.1	-1.3	-0.2
Reaction time premature initiation rate	0.5	0.7	1.5	0.8	-0.9	-0.7	1.2	-0.7	-0.8
Reaction time premature initiations	1.4	2.0	4.6	1.9	-0.3	-1.5	2.1	-0.8	-0.9
Std. dev. reaction times	1.4	1.9	4.4	-2.1	-1.4	1.4	-1.5	-0.3	-0.7
Reaction time trials completed	1.1	1.6	3.3	1.8	1.1	-1.3	1.7	-0.2	-0.2
Reaction time trials AUC	1.0	1.4	3.1	1.8	1.2	-1.1	1.7	-0.0	-0.1
Social response proportion	1.3	1.4	3.0	0.3	-1.7	-0.6	1.0	-1.2	-1.7
Social responses	1.0	1.3	2.5	0.4	-1.5	-1.1	0.6	-1.6	-1.2
Social time	2.4	3.1	6.4	-1.9	-2.4	1.5	-2.5	-0.2	-0.9
Conditioned locomotion	0.4	0.4	1.4	0.4	-0.7	-0.0	0.7	-0.3	-1.2
Cocaine response after cond. corrected	1.4	1.6	3.5	-0.8	-0.6	1.9	-1.1	1.9	0.6
Cocaine response after cond. not corrected	0.5	0.6	1.6	-0.5	-1.3	0.5	-0.7	-0.2	-0.8
Cocaine response before conditioning	4.8	5.9	15.7	1.1	-0.9	-3.0	1.4	-4.0	-2.6
Saline control response	3.3	4.4	8.2	2.9	2.0	-2.7	2.2	-1.2	-0.5
Condit. Reinf. active minus inactive responses	1.1	1.4	3.8	0.6	-0.0	-1.6	0.6	-1.9	-1.2
Condit. Reinf. active-inactive response ratio	1.7	1.8	5.3	0.4	-0.5	-1.5	0.5	-2.3	-1.6
Condit. Reinf. active responses	0.3	0.4	0.8	0.4	0.3	-0.9	0.3	-0.9	-0.5
Condit. Reinf. inactive responses	0.2	0.3	0.6	0.5	0.7	0.1	0.3	0.8	0.3
Condit. Reinf. lever presses	0.0	0.0	0.1	0.0	-0.2	-0.4	0.0	-0.2	0.2
Condit. Reinf. lever reinforcers received	0.2	0.3	0.8	0.2	0.1	-0.8	0.1	-0.9	-0.5
Pavlov. Cond. lever latency	0.1	0.1	0.3	-0.1	-0.5	0.4	-0.4	0.0	-0.6
Pavlov. Cond. magazine entry latency	0.2	0.3	1.1	-0.5	-1.0	-0.1	-0.2	-0.5	-0.0
Pavlov. Cond. change in total contacts	0.3	0.5	1.2	0.4	0.7	-1.1	0.4	-0.9	0.4
Pavlov. Cond. index score	0.1	0.1	0.2	-0.1	-0.2	-0.4	0.2	-0.4	0.3
Pavlov. Cond. latency score	0.1	0.2	0.4	0.1	-0.3	-0.6	0.4	-0.5	0.2
Pavlov. Cond. lever contacts	0.4	0.6	1.7	0.6	1.3	-0.7	0.5	0.1	0.9
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	0.2	0.2	0.1	0.0	0.0	-0.3
Pavlov. Cond. intertrial magazine entries	0.9	1.2	2.6	-1.4	-1.1	1.0	-1.6	-0.1	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.2	-0.0	-0.2	-0.5	0.3	-0.4	0.3
Pavlov. Cond. response bias	0.2	0.3	1.0	-0.2	0.7	-0.2	-0.1	0.1	1.0
Conditioned reinforcement - actives	0.3	0.3	0.8	0.4	-0.9	-0.4	0.6	-0.4	-0.5
Conditioned reinforcement - inactives	0.6	0.7	1.7	0.9	-0.1	-1.3	1.0	-0.9	0.1
Conditioned locomotion	0.3	0.3	0.8	0.1	-0.9	0.1	0.8	-0.0	-0.6
Intermittent access intake day 1-15 change	0.6	0.6	1.6	0.4	1.3	-0.9	-0.4	-0.5	0.6
Intermittent access intake escalation	0.2	0.2	0.5	-0.1	0.6	-0.2	-0.7	-0.1	0.3
Intermittent access intake escalation 2	1.1	1.1	2.6	-1.6	-0.8	0.9	-1.6	-0.1	0.0
Intermitt. access day 1 inactive lever presses	0.7	0.7	2.0	-0.2	-1.3	0.2	-0.3	-0.6	-1.4
Intermitt. access day 15 inactive lever presses	1.3	1.4	2.9	1.1	-0.6	-1.7	0.7	-1.7	-0.9
Intermitt. access escalation Index	1.9	1.7	3.2	-1.5	-0.1	1.8	-1.5	1.4	0.8
Intermittent access day 1 total infusions	0.4	0.4	0.8	-0.6	0.0	0.7	-0.2	0.8	0.9
Intermittent access day 15 total infusions	0.2	0.3	0.7	-0.2	0.6	0.3	-0.4	0.6	0.8
Intermittent access terminal intake (last 3 days)	0.0	0.1	0.1	0.1	0.1	-0.4	0.3	-0.2	0.2
Intermittent access total infusions	0.1	0.1	0.2	0.1	0.3	-0.1	0.4	0.2	0.4
Intermittent access day 1 locomotion	0.2	0.2	0.3	0.2	-0.5	0.2	0.6	0.4	-0.4
Intermittent access day 15 total locomotion	0.3	0.4	0.8	0.7	-0.0	-0.6	0.6	-0.5	-0.9
Intermittent access total locomotion	0.2	0.3	0.7	0.7	0.0	-0.3	0.8	0.1	-0.5
Intermittent access standard deviation	1.8	2.0	3.9	1.9	0.4	-2.0	1.5	-1.3	-0.7
Cocaine induced anxiety	1.6	1.8	4.1	-1.1	-0.7	2.0	-1.3	1.8	0.2
Post-drug Anxiety	0.5	0.5	1.2	-0.4	-1.1	0.9	-0.5	0.6	-0.7
Baseline Anxiety	0.7	0.8	1.8	0.6	-0.4	-1.1	0.8	-1.3	-0.7
Lifetime Intake	0.1	0.1	0.3	0.0	-0.4	-0.1	0.6	-0.0	0.1
Incentive Sensitization - Responses	0.9	0.9	2.2	-0.6	0.3	0.7	-1.5	0.9	1.3
Incentive Sensitization - Breakpoint	1.1	1.1	2.3	-0.6	0.4	0.8	-1.5	1.2	1.4
Progressive ratio test 1 active lever presses	0.1	0.1	0.1	-0.3	-0.3	0.2	0.3	0.1	0.0
Progressive ratio test 1 breakpoint	0.1	0.1	0.2	-0.2	-0.4	0.1	0.5	0.0	-0.1
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.3	0.5	0.3	-0.1	0.1	0.4	0.4
Progressive ratio test 2 active lever presses	0.4	0.5	1.0	-0.4	0.4	0.6	-0.6	0.9	1.0
Progressive ratio test 2 breakpoint	0.8	0.8	1.8	-0.4	0.6	0.7	-0.7	1.3	1.4
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.2	-0.3	-0.2	-0.2	0.1	-0.5	-0.0
Total sessions with >9 infusions	0.2	0.2	0.9	-0.1	-0.9	0.2	0.6	0.1	-0.2
Short access day 1 total inactive lever presses	1.0	1.1	3.6	-1.1	-1.9	0.8	-0.0	-0.4	-1.1
Short access day 10 total inactive lever presses	0.5	0.5	2.2	-0.6	-0.2	0.6	-1.5	0.0	-0.3
Short access day 1 total infusions	0.5	0.5	2.2	-0.6	-1.5	0.3	0.7	-0.2	-0.2
Short access day 10 total infusions	0.1	0.1	0.2	-0.1	-0.4	-0.1	0.2	-0.3	-0.2
Short access total infusions	0.4	0.4	1.4	-0.2	-1.2	-0.3	0.7	-0.7	-0.4
Short access day 1 locomotion	1.5	1.6	3.2	-1.4	-1.0	1.8	-1.2	1.3	0.5
Short access day 10 total locomotion	1.9	2.1	4.8	-0.1	-2.2	-0.5	0.1	-1.6	-2.2
Short access total locomotion	0.7	0.7	2.2	0.0	-1.5	0.1	0.5	-0.5	-1.3
Compulsive drug intake	3.0	2.9	6.8	-2.0	-0.8	2.1	-2.6	1.2	0.4
One hour access (0.3 mA shock)	2.0	2.3	4.2	-1.6	-0.1	1.7	-2.0	1.5	1.3
One hour access (shock baseline)	0.2	0.3	1.0	0.6	0.3	-0.5	1.0	-0.0	0.0
Number of responses in last shaping day	1.3	1.3	3.2	-0.8	-1.8	-0.3	0.0	-1.6	-1.1
Context. condit. distance diff. score	4.1	5.0	11.3	-2.8	-1.6	3.4	-1.9	2.0	0.2
Locomotion velocity, session 1	0.2	0.3	1.2	-1.1	0.1	0.3	-0.3	-0.3	0.1
Locomotion distance, session 1	1.2	1.6	3.0	-0.8	1.1	1.1	-1.1	1.5	1.7
Locomotion velocity, session 2	0.6	0.7	1.8	-1.2	-0.8	0.6	-1.3	-0.0	0.3
Locomotion distance, session 2	1.3	1.9	3.4	-1.3	0.2	1.8	-1.2	1.8	1.3
Locomotion velocity, session 3	0.4	0.5	1.6	0.6	1.3	-0.9	0.3	-0.4	0.4
Locomotion distance, session 3	1.6	1.7	2.6	-1.3	0.6	1.4	-1.1	1.5	1.6
Stereotopy head waving bouts, day 3	1.0	1.2	3.4	0.0	-0.6	-0.9	0.3	-1.8	-1.6
Stereotopy head waving duration, day 3	1.8	2.1	5.4	0.6	-0.5	-1.7	1.0	-2.3	-1.7
Locomotion velocity, session 7	4.5	4.9	9.9	-2.0	0.3	3.0	-1.4	3.1	2.1
Locomotion distance, session 7	4.6	5.8	9.0	-2.4	-0.2	2.9	-1.9	3.0	2.8
Stereotopy head waving bouts, day 7	1.0	1.1	3.9	-0.0	0.7	-1.6	-0.1	-2.0	-0.1
Stereotopy head waving duration, day 7	1.1	1.3	4.3	0.4	0.5	-1.7	0.2	-2.1	-0.6
Locomotion velocity, session 8	2.1	2.5	5.1	-2.3	-1.8	1.3	-1.7	-0.8	-1.3
Locomotion distance, session 8	4.8	7.1	16.0	-3.1	-1.3	4.0	-2.5	2.9	0.9
Degree of sensitization distance	0.8	0.8	3.0	-0.9	-1.7	0.8	-0.6	0.1	-0.4
Degree of sensitization stereotypy	0.6	0.7	1.9	-0.5	0.5	-1.0	-0.7	-1.4	0.5
Condit. Reinf. active minus inactive responses	0.2	0.2	0.7	-0.8	-0.1	0.2	-0.2	0.0	0.8
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.8	0.4	0.2	-0.9	0.5	-0.6	0.3
Condit. Reinf. active responses	0.5	0.6	1.3	-0.7	-0.1	0.8	-0.2	1.0	1.1
Condit. Reinf. inactive responses	1.8	2.1	5.5	-0.7	0.4	1.6	-0.7	2.3	2.0
Incentive salience index mean	1.7	2.0	4.2	-2.1	-1.2	1.8	-1.4	0.9	0.6
Condit. Reinf. lever presses	3.6	4.9	9.6	-2.6	-2.0	3.1	-2.2	1.9	0.5
Time in familiar zone, hab. session 1	1.7	1.6	5.4	0.2	1.1	0.3	-0.1	1.7	2.3
Time in novel zone, hab. session 1	1.7	1.6	5.6	0.3	-0.3	-0.7	0.7	-1.7	-2.4
Total zone transitions, hab. session 1	0.5	0.7	1.5	-0.8	0.0	1.0	-1.2	0.9	0.7
Total locomotion distance, hab. session 1	0.6	0.9	1.4	-0.7	-0.1	1.2	-1.0	1.2	0.8
Locomotion velocity, hab. session 1	0.4	0.5	1.0	-0.6	-0.4	0.8	-1.0	0.8	0.8
Time in familiar zone, hab. session 2	0.2	0.2	0.5	0.5	-0.0	-0.2	-0.6	0.5	0.7
Time in novel zone, hab. session 2	0.9	0.9	2.0	0.3	1.4	-0.6	1.3	-0.8	-0.6
Total zone transitions, hab. session 2	0.6	0.7	1.9	-0.3	0.2	0.9	-1.4	1.1	0.6
Total locomotion distance, hab. session 2	1.9	2.5	5.1	-0.9	0.2	2.0	-1.8	2.2	1.3
Locomotion velocity, hab. session 2	2.3	3.1	5.3	-1.3	-0.2	2.3	-2.1	2.3	1.4
Novel to familiar place preference ratio	0.2	0.3	0.9	-0.5	0.9	-0.0	-0.0	-0.1	0.6
Novelty place preference	0.2	0.3	0.8	-0.5	0.9	-0.3	0.1	-0.5	0.4
Time in novel zone, NPP test	0.3	0.3	0.8	-0.3	0.9	-0.5	0.2	-0.8	0.2
Total zone transitions, NPP test	1.5	2.1	3.7	-1.2	0.6	1.9	-1.6	1.9	1.1
Total locomotion distance, NPP test	1.8	2.5	6.5	-0.8	0.9	2.2	-0.8	2.5	1.3
Locomotion velocity, NPP test	2.7	3.9	9.5	-1.2	1.0	2.7	-1.2	3.1	1.7
Pavlov. Cond. lever latency	3.6	4.6	10.2	3.2	2.6	-2.2	2.4	-0.4	-0.3
Pavlov. Cond. magazine entry latency	1.7	2.2	5.0	-2.2	-2.1	0.9	-1.7	-0.6	-0.1
Pavlov. Cond. change in total contacts	1.9	2.0	6.7	-1.6	-2.6	0.1	-1.2	-1.2	-0.2
Pavlov. Cond. index score	3.7	4.7	9.7	-3.1	-3.1	1.9	-2.4	-0.0	0.1
Pavlov. Cond. latency score	3.9	5.0	10.3	-3.2	-3.0	1.9	-2.6	-0.2	0.1
Pavlov. Cond. lever contacts	3.6	4.2	9.0	-2.8	-3.0	2.1	-2.0	0.3	-0.0
Pavlov. Cond. magazine entry number	1.4	1.7	4.8	1.7	2.2	-0.8	1.3	0.3	0.1
Pavlov. Cond. intertrial magazine entries	2.0	2.4	7.4	1.3	2.7	0.0	1.4	1.5	1.0
Pavlov. Cond. lever-magazine prob. diff.	3.6	4.5	9.7	-3.0	-3.1	1.8	-2.2	0.0	0.1
Pavlov. Cond. response bias	2.4	3.0	7.9	-2.4	-2.8	1.4	-1.4	-0.1	-0.2
Bone: apparent density	2.0	3.3	7.3	-0.7	1.9	1.7	-1.0	2.7	2.2
Bone surface	0.1	0.1	0.6	-0.2	-0.3	0.2	-0.7	-0.1	-0.3
Bone volume	0.1	0.2	0.5	0.2	0.7	0.2	-0.3	0.6	0.5
Bone: connectivity density	1.8	2.9	8.2	-0.8	1.1	2.2	-0.8	2.9	1.3
Bone: cortical apparent density	1.0	1.3	3.2	1.8	1.5	-1.1	0.9	0.3	0.5
Bone: cortical area	0.3	0.5	1.2	0.4	-0.4	-0.9	-0.6	-1.1	-0.4
Bone: cortical porosity	1.2	1.3	4.0	0.0	0.3	-1.8	0.6	-2.0	0.3
Bone: cortical porosity	1.3	1.4	5.6	-0.4	-0.3	-1.5	0.2	-2.4	-0.3
Bone: cortical thickness	0.9	1.5	2.7	1.5	1.6	-1.6	0.1	-0.3	1.1
Bone: cortical thickness	0.8	1.0	2.6	1.6	1.1	-1.0	0.4	0.4	0.9
Bone: cortical tissue density	0.9	1.2	3.2	1.8	1.4	-1.1	1.0	0.2	0.3
Bone: elastic displacement	0.8	0.9	3.6	0.2	1.9	-0.8	0.7	-0.3	0.9
Bone: elastic work	0.5	0.6	1.5	0.4	1.2	-1.0	0.5	-0.9	0.1
Bone: endosteal estimation	3.7	8.0	19.4	0.7	-3.2	-1.7	1.0	-3.7	-4.4
Bone: endosteal perimeter	2.0	4.1	12.2	-0.9	-3.5	0.3	-0.5	-1.7	-2.9
Bone: final force	1.2	1.9	4.5	2.1	0.3	-1.9	1.0	-1.2	-0.8
Bone: final moment	1.2	1.9	4.2	2.1	0.3	-2.0	1.1	-1.2	-0.8
Bone: marrow area	3.9	8.3	20.2	0.8	-3.2	-1.9	1.2	-3.8	-4.5
Bone: maximum diameter	1.2	2.2	5.5	-1.2	-2.3	0.5	-1.6	-1.1	-1.4
Bone: maximum force	1.0	1.7	3.4	1.7	0.6	-1.8	1.0	-1.3	-0.8
Bone: maximum moment	1.0	1.8	3.5	1.7	0.6	-1.9	1.0	-1.5	-0.9
Bone: minimum diameter	1.7	3.1	9.5	-0.4	-3.1	-0.1	-0.6	-1.6	-2.4
Bone: periosteal estimation	2.3	4.8	10.1	1.0	-2.2	-1.8	0.5	-3.0	-3.2
Bone: periosteal perimeter	1.1	1.9	4.3	-0.3	-2.1	-0.5	-0.5	-1.7	-1.9
Bone: post-yield work	0.4	0.6	2.6	-0.0	-0.8	0.3	0.1	-0.4	-1.6
Bone: stiffness	0.3	0.4	1.7	1.3	0.2	-0.9	0.2	-0.1	-0.1
Bone: tissue strength	0.6	0.6	1.7	0.6	1.3	-0.7	0.8	-0.4	-0.0
Bone: trabecular number	3.0	4.6	8.9	-0.8	2.4	1.9	-1.1	3.0	2.7
Bone: trabecular spacing	3.2	4.2	8.0	1.1	-2.1	-2.0	1.2	-2.8	-2.4
Bone: trabecular thickness	1.7	2.0	5.1	-0.4	1.3	1.3	-0.7	2.3	1.7
Bone: trabecular tissue density	1.0	1.4	4.2	0.3	-1.0	-1.7	0.1	-2.1	-0.2
Breakpoint value in progressive ratio session	0.5	0.6	1.0	-1.0	-0.6	0.9	-0.9	0.5	0.4
Distance traveled before self-admin	0.4	0.4	0.8	-0.0	-0.7	0.9	-0.4	0.7	-0.7
Distance traveled after self-admin	1.0	1.1	2.6	0.9	-0.4	-1.1	0.3	-1.3	-1.6
Delta time in closed arm before/after self-admin	0.4	0.4	1.4	0.5	0.0	-0.2	0.7	-0.4	-1.2
Delta time in open arm before/after self-admin	0.2	0.2	0.4	0.6	0.5	-0.6	0.0	-0.1	0.5
Diff in mean of infusions in LGA sessions	3.8	4.2	6.7	-1.8	-0.0	2.6	-2.3	2.6	1.9
Extinction: sum of active levers before priming	0.3	0.3	0.8	-0.9	-0.3	0.7	-0.5	0.3	0.3
Active lever presses in extinction session 6	0.5	0.5	1.7	0.6	0.9	-0.1	1.3	0.4	0.2
Delta distance traveled before/after self-admin	2.1	2.2	5.6	1.0	0.5	-2.3	0.8	-2.4	-0.8
Delta ambulatory time before/after self-admin	1.1	1.2	3.7	0.4	0.0	-1.6	0.2	-1.9	-0.8
Time in closed arm before self-admin	0.1	0.1	0.2	0.1	-0.5	-0.2	0.4	-0.3	-0.2
Time in closed arm after self-admin	0.2	0.2	0.3	0.5	0.5	-0.5	0.5	-0.3	-0.0
Time in open arm before self-admin	0.2	0.2	1.0	-1.0	0.2	0.2	-0.5	-0.3	0.2
Time in open arm after self-admin	0.1	0.1	0.3	-0.3	0.1	-0.4	-0.2	-0.5	0.1
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.3	-0.5	-0.3	0.2	0.5	-0.2	-0.2
Time to tail flick, vehicle, before self-admin	1.6	1.6	3.7	-1.0	-0.1	1.5	-1.9	1.4	0.8
Time to tail flick, vehicle, after self-admin	0.7	0.8	1.8	-1.2	-0.7	1.3	-0.8	0.6	-0.2
Time to tail flick, test, before self-admin	0.5	0.5	1.0	-0.2	0.9	0.0	-1.0	0.3	1.0
Time to tail flick, test, after self-admin	1.6	1.6	3.0	-1.3	1.1	1.1	-1.7	1.0	1.3
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.5	-0.5	0.4	0.3	0.7	0.2	0.2
Delta time to tail flick, test, before/after SA	0.8	0.7	2.1	-0.1	0.8	1.0	0.0	1.4	0.6
Ambulatory time before self-admin	0.2	0.2	0.4	-0.1	0.4	0.6	-0.5	0.7	0.1
Ambulatory time after self-admin	0.6	0.6	1.4	0.5	-0.3	-0.9	0.1	-1.2	-1.1
Total heroin consumption	0.1	0.1	0.4	-0.1	0.6	0.0	-0.1	0.0	0.0
Area under the delay curve	0.4	0.4	1.6	-0.2	-0.1	-0.8	0.2	-1.3	-0.0
Delay disc. indifference point, 0s delay	0.4	0.4	0.9	-0.9	-1.0	0.5	-0.4	-0.4	-0.4
Delay disc. indifference point, 16s delay	0.4	0.4	0.9	0.3	0.8	-0.8	0.1	-0.4	1.0
Delay disc. indifference point, 2s delay	1.4	1.6	4.5	-0.4	-1.4	-1.1	0.6	-2.1	-1.1
Delay disc. indifference point, 24s delay	0.8	0.8	1.8	0.6	-0.3	-1.3	1.0	-1.3	-0.2
Delay disc. indifference point, 4s delay	1.5	1.5	4.5	0.3	-0.8	-1.5	0.6	-2.1	-1.2
Delay disc. indifference point, 8s delay	0.1	0.1	0.4	-0.6	0.3	-0.1	-0.1	-0.4	0.4
Delay discount exponential model param	0.5	0.6	2.1	0.2	0.2	1.0	-0.2	1.5	0.1
Delay discount hyperbolic model param	0.7	0.7	2.9	0.2	0.3	1.1	-0.2	1.7	0.3
Fecal boli incidents, locomotor time 1	0.2	0.3	0.8	0.4	-0.3	0.2	0.9	0.7	-0.1
Change in fecal boli incidents, locomotor task	1.0	1.0	2.1	-0.9	-1.5	0.1	-1.0	-1.1	-0.8
Time >=10cm from walls, locomotor time 1	1.1	1.1	4.6	0.5	-1.0	-0.0	0.5	-0.5	-2.2
Bouts of movement, locomotor time 1	0.9	1.0	2.2	-1.2	0.4	1.2	-1.5	0.9	0.6
Total resting periods, locomotor time 1	0.7	0.7	1.7	-1.1	0.2	1.1	-1.3	0.6	0.3
Rest time, locomotor task time 1	0.2	0.3	0.7	-0.2	-0.3	-0.3	0.2	-0.8	-0.8
Distance moved, locomotor task time 1	0.2	0.2	0.5	0.7	0.3	-0.5	0.4	-0.2	0.1
Vertical activity count, locomotor time 1	0.4	0.4	0.9	0.9	0.8	-0.5	0.8	0.1	0.0
Time >=10cm from walls, locomotor time 2	1.3	1.4	4.1	0.5	-1.4	-0.2	1.3	-0.6	-2.0
Bouts of movement, locomotor time 2	0.5	0.6	2.1	-0.1	0.0	-0.9	-0.3	-1.4	-0.6
Total resting periods, locomotor time 2	0.7	0.8	2.6	-0.5	-0.3	-0.7	-0.6	-1.6	-0.8
Rest time, locomotor task time 2	1.1	1.2	1.7	-1.3	-1.2	1.3	-1.1	0.2	-1.1
Distance moved, locomotor task time 2	0.8	0.9	2.7	1.3	0.8	-0.6	1.6	0.3	0.3
Vertical activity count, locomotor time 2	0.7	0.8	2.9	1.2	0.5	-0.5	1.7	0.2	-0.2
Weight adjusted by age	3.9	4.4	7.3	1.6	-0.9	-2.0	2.6	-2.2	-2.7
Seeking ratio, delayed vs. immediate footshock	0.9	1.0	2.5	0.8	-0.3	-1.6	-0.2	-1.6	-0.6
Locomotion in novel chamber	0.1	0.1	0.4	0.2	0.2	-0.6	-0.1	-0.6	-0.1
Locomotion in novel chamber post-restriction	0.7	0.8	1.7	1.2	0.2	-0.9	1.3	-0.5	-0.7
Progressive ratio	3.1	3.6	7.0	2.6	1.1	-2.6	1.4	-1.8	-1.3
Food seeking constrained by brief footshock	0.1	0.2	0.3	0.5	0.3	-0.5	0.6	-0.2	-0.0
Seeking ratio, punishment vs. effort	1.8	2.2	4.5	-2.1	-1.1	1.9	-1.1	1.2	0.9
Run reversals in cocaine runway, females	0.7	0.7	1.9	0.9	1.4	-0.5	0.9	0.5	0.7
Run reversals in cocaine runway, males	0.4	0.4	0.8	-0.9	-0.5	0.4	-0.7	-0.4	-0.6
Latency to leave start box in cocaine runway	0.7	0.8	1.6	-1.3	-1.0	0.9	-1.0	0.2	0.2
Latency to leave start box in cocaine runway, F	0.9	1.0	1.7	-1.3	-0.9	1.3	-1.1	0.7	0.4
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	-0.1	-0.0	-0.2	-0.5	-0.3	0.2
Cd content in liver	0.9	0.9	1.6	1.1	1.1	0.1	1.2	1.3	0.6
Co content in liver	1.6	1.9	4.1	2.0	0.6	-1.6	1.9	-0.6	-0.6
Cu content in liver	2.3	2.8	7.5	-0.8	1.4	1.1	-0.7	2.2	2.7
Fe content in liver	1.4	1.7	4.1	1.6	1.4	-1.2	2.0	-0.1	0.0
K content in liver	1.1	1.1	2.4	-1.3	-0.6	1.2	-1.6	0.6	0.6
Mg content in liver	4.0	4.2	8.1	-2.8	-2.0	2.2	-2.8	0.4	0.0
Mn content in liver	3.1	3.5	7.3	-2.1	-2.7	1.7	-1.8	-0.5	-1.7
Na content in liver	0.7	0.8	2.2	-0.9	-0.4	0.5	-1.5	0.3	1.0
Rb content in liver	0.7	0.9	2.3	-0.5	-0.0	1.5	-0.6	1.5	0.0
Se content in liver	3.1	3.7	7.8	-2.7	-2.8	1.1	-2.1	-1.1	-0.5
Sr content in liver	1.1	1.0	2.9	0.3	-1.7	-0.1	1.1	-0.5	-1.2
Zn content in liver	0.5	0.6	2.5	-0.3	-1.6	0.6	0.1	0.2	-0.6