Best TWAS P = 3.65e-08 · Best GWAS P= 5.52e-08 conditioned to 9.11e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Ccdc177 | gene expression | Ccdc177 | 0.07 | 1 | 0.04 | 4.3e-05 | -5.22 | 1.82e-07 | 0.91 | FALSE |
| Adipose | Cox16 | gene expression | Cox16 | 0.04 | 1 | 0.04 | 1.9e-05 | -5.39 | 6.92e-08 | 0.97 | TRUE |
| IL | Srsf5 | isoform ratio | XR_010052053.1 | 0.74 | 34 | 0.22 | 4.2e-06 | -5.51 | 3.65e-08 | 0.25 | TRUE |
| LHb | Srsf5 | alternative TSS | XM_039111859.2 | 0.22 | 2501 | 0.06 | 1.8e-02 | 5.5 | 3.88e-08 | 0.32 | FALSE |
| pVTA | Adam4 | gene expression | Adam4 | 0.08 | 7 | 0.02 | 4.3e-03 | -5.42 | 6.06e-08 | 0.79 | FALSE |