chr3:121,057,309-123,489,307

Trait: Tail length

Best TWAS P=2.76e-09 · Best GWAS P=6.30e-10 conditioned to 3.72e-14

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Plcb4 intron excision ratio chr3_123027184_123040677 0.02 1 0.01 2.0e-02 5.43 5.76e-08 0.04 FALSE
BLA Plcb1 alternative polyA NM_001077641.2 0.06 35 0.05 8.9e-04 -5.31 1.08e-07 0.13 FALSE
BLA Plcb4 intron excision ratio chr3_123040745_123107068 0.05 1382 0.02 3.8e-02 -5.86 4.57e-09 0.39 FALSE
Brain Plcb1 intron excision ratio chr3_122686087_122697900 0.03 1102 0.03 1.2e-03 5.42 6.10e-08 0.14 FALSE
Brain Plcb1 intron excision ratio chr3_122686087_122769694 0.02 1102 0.01 2.0e-02 -5.55 2.92e-08 0.2 FALSE
Brain Plcb4 mRNA stability Plcb4 0.08 1382 0.07 2.6e-07 -5.68 1.36e-08 0.31 FALSE
IL Plcb1 gene expression Plcb1 0.34 1 0.19 2.3e-05 -5.29 1.24e-07 0.06 FALSE
IL Tmx4 gene expression Tmx4 0.14 1139 0.04 4.5e-02 -5.44 5.24e-08 0.15 FALSE
Liver LOC103691897 gene expression LOC103691897 0.05 1 0.05 1.8e-06 5.77 8.02e-09 0.62 FALSE
Liver Plcb1 gene expression Plcb1 0.08 32 0.1 4.9e-11 5.28 1.32e-07 0.09 TRUE
NAcc Plcb1 isoform ratio NM_001077641.2 0.05 1102 0.06 3.3e-07 -5.81 6.27e-09 0.31 FALSE
NAcc Plcb1 isoform ratio XM_017591467.2 0.06 1102 0.06 2.9e-07 5.9 3.72e-09 0.28 FALSE
NAcc Plcb1 intron excision ratio chr3_122686087_122769694 0.03 1102 0.01 6.8e-03 -5.92 3.28e-09 0.64 FALSE
OFC Plcb4 gene expression Plcb4 0.5 27 0.45 5.6e-12 5.44 5.32e-08 0.33 FALSE
OFC Tmx4 gene expression Tmx4 0.19 1 0.09 4.6e-03 5.29 1.24e-07 0.05 FALSE
OFC Plcb1 isoform ratio NM_001077641.2 0.16 1 0.1 2.6e-03 5.22 1.79e-07 0.05 FALSE
PL Plcb1 alternative polyA NM_001077641.2 0.03 1102 0.03 1.5e-04 -5.73 1.03e-08 0.46 FALSE
PL Plcb1 alternative polyA XM_017591467.2 0.02 1102 0.02 1.1e-03 5.46 4.83e-08 0.17 FALSE
PL Plcb1 isoform ratio NM_001077641.2 0.05 100 0.06 2.6e-07 5.95 2.76e-09 0.16 TRUE
PL Plcb1 intron excision ratio chr3_122686087_122697900 0.02 1102 0.01 9.2e-03 5.56 2.77e-08 0.21 FALSE
PL Plcb4 intron excision ratio chr3_123040745_123107068 0.16 1382 0.1 6.2e-11 -5.34 9.14e-08 0.27 FALSE
pVTA Plcb1 mRNA stability Plcb1 0.19 1102 0.25 4.8e-11 5.22 1.74e-07 0.09 FALSE