Snf8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio ENSRNOT00000008964 0.04 0.02 3.7e-06 0.04 0.04 0.05 0.05 1.0e-05 6.8e-05 3.8e-06 3.3e-06
2 Adipose intron excision ratio chr10:80984820:80990408 0.02 0.02 4.9e-04 0.01 0.01 0.02 0.01 1.0e-02 4.9e-02 5.7e-03 4.6e-02
3 BLA mRNA stability ENSRNOG00000006500 0.1 0.09 7.2e-04 0.02 0.04 0.03 0.02 4.4e-02 3.2e-03 1.7e-02 2.1e-02
4 Brain isoform ratio ENSRNOT00000008964 0.1 0.07 9.9e-08 0.06 0.07 0.06 0.07 5.1e-06 6.7e-07 1.6e-06 1.1e-06
5 Brain intron excision ratio chr10:80984820:80990408 0.08 0.05 2.2e-10 0.1 0.11 0.11 0.11 2.2e-09 1.6e-10 1.2e-10 1.4e-10
6 Liver gene expression ENSRNOG00000006500 0.05 0.03 7.2e-08 0.07 0.04 0.07 0.07 5.0e-08 5.7e-05 8.4e-08 5.2e-08
7 Liver intron excision ratio chr10:80984820:80990408 0.13 0.07 6.9e-12 0.1 0.04 0.1 0.07 1.7e-11 1.3e-05 1.4e-11 2.9e-08
8 PL intron excision ratio chr10:80984820:80990408 0.1 0.07 1.9e-06 0.07 0.07 0.08 0.07 2.5e-06 5.3e-06 1.1e-06 2.3e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail17.055.266.07.17.9-8.16.57.27.66.78.1
BMI without tail1.12.44.51.41.7-1.70.91.41.31.62.1
Body weight1.14.65.72.42.4-2.11.82.32.21.62.1
Epididymis fat weight0.10.20.40.30.6-0.60.20.40.50.20.4
Glucose0.91.41.81.41.3-1.21.21.31.20.90.9
Heart weight1.62.23.41.81.5-1.70.91.51.41.81.1
Left kidney weight0.00.00.10.10.1-0.00.20.10.10.0-0.3
Right kidney weight0.51.42.11.21.2-1.11.41.41.21.00.7
Tail length15.246.154.6-6.2-7.17.4-6.4-6.5-7.1-6.2-7.3
Length with tail7.226.537.6-4.2-5.25.9-4.5-4.5-5.3-5.1-6.1
Length without tail0.10.10.40.40.10.10.30.30.2-0.5-0.7
Liver weight, left0.61.01.5-0.8-1.01.2-1.1-0.9-1.2-1.0-0.9
Liver weight, right0.40.61.1-0.7-0.50.9-0.7-0.5-0.7-1.1-1.1
Parametrial fat weight0.10.30.7-0.8-0.50.3-0.7-0.4-0.50.1-0.3
Retroperitoneal fat weight0.30.91.80.60.7-0.90.70.91.01.41.2
Intraocular pressure1.42.02.2-1.5-1.41.5-1.2-1.4-1.5-1.4-1.4
Extensor digitorum longus weight0.83.24.52.02.1-1.61.92.01.80.71.7
Soleus weight1.75.17.12.72.4-2.22.12.42.01.92.2
Tibialis anterior weight0.10.31.1-0.2-0.20.6-0.3-0.4-0.5-1.00.4
Tibia length0.61.62.41.61.3-1.31.31.21.20.90.9
Number of licking bursts1.11.32.4-1.6-1.30.7-1.4-1.3-1.0-0.5-1.1
Food consumed during 24 hour testing period2.12.52.8-1.7-1.71.6-1.5-1.6-1.6-1.5-1.4
Times rat made contact with spout0.80.91.5-1.2-1.00.7-1.0-1.0-1.0-0.4-1.0
Mean time between licks in bursts0.50.71.20.61.0-1.01.10.71.10.4-0.1
Mean num. licks in bursts0.10.10.40.60.4-0.00.50.50.2-0.1-0.0
Std. dev. time between licks in bursts0.70.91.40.70.8-0.91.00.90.91.20.9
Water consumed over 24 hours0.10.20.4-0.3-0.40.3-0.2-0.4-0.2-0.6-0.7
Indifference point 0 sec1.52.43.21.71.4-1.21.71.81.71.21.5
Indifference point AUC0.10.10.1-0.3-0.30.3-0.1-0.3-0.0-0.3-0.2
Indifference point function ln k0.00.00.1-0.1-0.20.3-0.1-0.1-0.3-0.2-0.0
Indifference point function log k0.00.00.1-0.1-0.20.3-0.1-0.1-0.3-0.2-0.0
Delay discounting total patch changes 0 sec1.62.63.41.81.5-1.31.81.81.81.31.4
Delay discounting total patch changes 12 sec0.10.10.20.2-0.0-0.30.20.20.50.40.1
Delay discounting total patch changes 18 sec2.33.13.81.81.7-1.61.91.92.01.51.5
Delay discounting total patch changes 24 sec1.51.92.61.41.1-1.11.31.41.41.61.6
Delay discounting total patch changes 6 sec1.11.62.41.31.1-1.11.31.41.51.11.3
Delay discounting time to switch 0 sec0.10.10.2-0.5-0.40.2-0.5-0.3-0.30.2-0.1
Delay discounting water rate 0 sec1.93.03.92.01.9-1.61.81.71.71.21.9
Delay discounting water rate 12 sec0.50.81.61.31.1-0.61.10.90.9-0.20.5
Delay discounting water rate 18 sec0.10.10.4-0.20.10.00.0-0.30.1-0.6-0.3
Delay discounting water rate 24 sec1.31.82.21.41.4-1.41.41.31.50.91.3
Delay discounting water rate 6 sec0.10.10.80.10.3-0.10.30.20.20.00.9
Locomotor activity0.20.31.10.00.3-0.60.20.30.50.91.0
Locomotor testing distance0.50.82.10.10.4-1.00.30.51.01.21.4
Locomotor testing rearing0.20.21.3-0.10.1-0.40.00.20.50.41.1
Light reinforcement 10.10.20.50.30.1-0.20.00.30.20.70.7
Light reinforcement 20.30.40.7-0.7-0.80.6-0.8-0.5-0.7-0.0-0.5
Reaction time number correct0.91.22.61.21.3-1.01.60.91.40.10.4
Reaction time mean minus median1.82.33.1-1.4-1.61.7-1.6-1.2-1.8-1.2-1.6
Reaction time mean minus median AUC2.63.34.6-1.8-1.81.9-2.0-1.6-2.1-1.4-1.9
Reaction time num false alarms0.81.11.7-1.1-1.21.1-1.0-1.2-1.3-0.7-0.8
Reaction time num false alarms AUC0.91.31.7-1.3-1.31.2-1.0-1.3-1.3-0.8-0.9
Reaction time trials correct on left0.91.22.61.21.3-1.01.60.91.40.10.4
Reaction time trials on left0.81.12.41.21.2-1.01.60.91.30.10.4
Reaction time mean0.81.12.4-0.9-1.01.1-1.3-0.8-1.6-0.6-0.9
Reaction time mean AUC1.01.32.8-1.0-1.01.2-1.5-0.9-1.7-0.7-1.0
Median of all reaction times0.20.31.1-0.4-0.40.5-0.9-0.3-1.1-0.0-0.2
Reaction time omissions1.11.42.1-1.4-1.31.2-1.2-1.2-1.4-0.6-1.0
Reaction time false alarm rate1.42.02.9-1.6-1.71.4-1.6-1.5-1.7-0.6-0.9
Reaction time premature initiation rate0.40.51.0-0.5-0.70.8-0.4-0.6-0.6-1.0-0.9
Reaction time premature initiations0.20.21.10.1-0.10.40.3-0.20.1-1.0-0.7
Std. dev. reaction times1.72.33.7-1.4-1.51.7-1.6-1.2-1.9-1.1-1.6
Reaction time trials completed0.81.12.41.21.2-1.01.60.91.30.10.4
Reaction time trials AUC0.81.22.51.21.3-1.01.60.91.40.10.4
Social response proportion1.82.02.7-1.4-1.51.6-1.4-1.4-1.6-1.0-1.0
Social responses0.00.10.2-0.4-0.10.20.0-0.2-0.0-0.20.4
Social time0.10.20.6-0.8-0.2-0.2-0.1-0.70.2-0.20.1
Conditioned locomotion1.31.52.90.91.2-1.51.41.01.71.10.8
Cocaine response after cond. corrected6.06.78.12.32.8-2.72.32.62.52.52.9
Cocaine response after cond. not corrected3.33.74.41.72.0-2.01.81.92.01.92.1
Cocaine response before conditioning2.83.54.1-1.8-2.02.0-1.6-2.0-1.8-1.7-2.0
Saline control response0.10.20.5-0.7-0.1-0.4-0.2-0.50.4-0.2-0.4
Condit. Reinf. active minus inactive responses0.20.20.5-0.6-0.50.1-0.7-0.5-0.50.40.1
Condit. Reinf. active-inactive response ratio0.30.40.9-0.8-0.6-0.0-0.9-0.7-0.40.60.2
Condit. Reinf. active responses0.10.10.2-0.2-0.30.2-0.5-0.3-0.40.10.0
Condit. Reinf. inactive responses0.00.10.20.40.20.10.30.20.1-0.4-0.2
Condit. Reinf. lever presses0.40.51.1-0.4-0.71.0-0.4-0.5-0.6-1.1-0.9
Condit. Reinf. lever reinforcers received0.10.10.3-0.2-0.30.2-0.5-0.3-0.4-0.1-0.1
Pavlov. Cond. lever latency1.62.33.4-1.7-1.51.2-1.9-1.8-1.5-1.0-1.3
Pavlov. Cond. magazine entry latency0.50.61.6-0.5-0.70.9-0.3-0.4-0.8-0.9-1.3
Pavlov. Cond. change in total contacts0.40.61.30.60.7-0.41.10.90.80.50.6
Pavlov. Cond. index score0.40.51.00.90.7-0.41.00.90.60.50.4
Pavlov. Cond. latency score0.20.20.60.60.4-0.10.80.70.30.20.1
Pavlov. Cond. lever contacts1.11.52.31.31.3-1.01.51.41.30.91.1
Pavlov. Cond. magazine entry number0.10.10.3-0.4-0.2-0.1-0.5-0.4-0.00.10.5
Pavlov. Cond. intertrial magazine entries1.82.32.9-1.7-1.51.3-1.7-1.7-1.3-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.50.71.31.00.8-0.51.11.00.70.50.4
Pavlov. Cond. response bias0.81.11.71.11.1-0.91.31.21.00.80.8
Conditioned reinforcement - actives0.30.30.6-0.6-0.3-0.1-0.7-0.4-0.50.80.3
Conditioned reinforcement - inactives0.10.10.3-0.5-0.20.0-0.5-0.50.0-0.3-0.6
Conditioned locomotion0.50.63.0-0.00.2-0.80.10.20.21.71.0
Intermittent access intake day 1-15 change1.21.22.70.60.8-1.00.91.01.11.61.4
Intermittent access intake escalation0.80.82.70.40.5-0.70.60.80.81.61.2
Intermittent access intake escalation 21.01.02.30.40.7-0.90.70.81.01.51.3
Intermitt. access day 1 inactive lever presses0.00.00.1-0.20.0-0.2-0.3-0.2-0.0-0.00.3
Intermitt. access day 15 inactive lever presses1.61.72.31.41.4-1.21.51.41.40.91.0
Intermitt. access escalation Index0.20.20.7-0.4-0.50.2-0.4-0.1-0.40.80.2
Intermittent access day 1 total infusions0.81.01.6-0.7-0.80.7-1.2-1.0-1.2-0.9-1.3
Intermittent access day 15 total infusions0.30.40.7-0.7-0.70.4-0.9-0.6-0.60.2-0.4
Intermittent access terminal intake (last 3 days)0.10.10.4-0.5-0.30.0-0.6-0.3-0.30.3-0.2
Intermittent access total infusions0.20.20.4-0.4-0.30.2-0.7-0.4-0.4-0.2-0.6
Intermittent access day 1 locomotion2.12.13.2-1.4-1.61.2-1.7-1.5-1.8-0.7-1.5
Intermittent access day 15 total locomotion0.40.50.9-0.8-0.80.3-0.9-0.6-0.60.5-0.6
Intermittent access total locomotion0.60.61.2-0.9-0.90.4-1.1-0.8-0.90.6-0.6
Intermittent access standard deviation1.21.33.30.70.9-1.10.91.01.11.81.2
Cocaine induced anxiety0.10.10.1-0.4-0.1-0.3-0.2-0.20.10.40.3
Post-drug Anxiety1.21.32.2-1.5-1.20.7-1.5-1.4-0.9-0.6-0.9
Baseline Anxiety0.00.00.00.10.1-0.10.10.10.2-0.0-0.1
Lifetime Intake0.30.30.4-0.6-0.50.4-0.6-0.6-0.6-0.4-0.6
Incentive Sensitization - Responses0.20.20.6-0.6-0.2-0.2-0.8-0.5-0.00.4-0.2
Incentive Sensitization - Breakpoint0.20.20.4-0.5-0.0-0.4-0.6-0.30.20.60.2
Progressive ratio test 1 active lever presses1.11.11.4-1.1-1.10.9-1.2-1.2-1.1-1.0-0.9
Progressive ratio test 1 breakpoint1.31.31.6-1.2-1.10.9-1.2-1.2-1.1-1.1-1.1
Progressive ratio test 1 inactive lever presses0.20.20.50.20.5-0.50.50.30.50.10.7
Progressive ratio test 2 active lever presses1.11.22.2-1.3-1.10.7-1.5-1.3-1.0-0.5-1.0
Progressive ratio test 2 breakpoint0.60.71.4-1.1-0.80.4-1.2-1.0-0.7-0.4-0.7
Progressive ratio test 2 inactive lever presses0.00.00.1-0.20.1-0.2-0.3-0.20.10.0-0.2
Total sessions with >9 infusions0.60.71.3-0.9-1.20.9-0.8-0.8-1.10.2-0.5
Short access day 1 total inactive lever presses0.50.51.9-0.5-0.40.9-0.2-0.5-0.4-1.4-0.8
Short access day 10 total inactive lever presses0.20.30.60.40.7-0.60.50.30.8-0.20.2
Short access day 1 total infusions0.10.10.3-0.2-0.40.50.1-0.1-0.3-0.2-0.1
Short access day 10 total infusions0.10.10.20.1-0.0-0.1-0.3-0.0-0.40.4-0.5
Short access total infusions0.00.00.10.1-0.10.10.10.0-0.2-0.1-0.3
Short access day 1 locomotion0.10.10.90.0-0.1-0.10.10.1-0.20.90.4
Short access day 10 total locomotion0.80.91.9-0.9-1.00.6-1.1-0.8-1.40.7-0.5
Short access total locomotion0.20.30.9-0.2-0.50.1-0.4-0.2-0.81.0-0.1
Compulsive drug intake7.27.29.6-2.6-2.62.8-2.5-2.8-2.7-3.1-2.3
One hour access (0.3 mA shock)0.80.91.4-1.1-0.80.7-1.2-1.2-0.9-1.0-0.7
One hour access (shock baseline)1.31.53.20.81.1-1.50.71.01.31.81.2
Number of responses in last shaping day1.51.62.31.41.5-1.31.51.21.50.20.6
Context. condit. distance diff. score0.91.11.51.01.1-1.11.01.11.20.51.1
Locomotion velocity, session 10.10.10.3-0.1-0.2-0.1-0.3-0.1-0.20.60.2
Locomotion distance, session 14.35.56.6-2.1-2.52.4-2.5-2.4-2.6-1.8-2.4
Locomotion velocity, session 21.11.32.4-0.7-1.21.3-0.9-0.9-1.3-1.0-1.5
Locomotion distance, session 26.18.710.6-3.0-3.22.9-3.1-3.1-3.1-2.1-2.9
Locomotion velocity, session 30.40.51.11.00.8-0.31.00.90.60.10.2
Locomotion distance, session 31.71.83.2-1.0-1.31.5-1.0-1.2-1.2-1.8-1.5
Stereotopy head waving bouts, day 34.55.46.32.32.4-2.32.22.52.02.42.4
Stereotopy head waving duration, day 33.44.15.02.02.1-2.02.02.21.92.11.9
Locomotion velocity, session 71.21.42.0-1.1-1.11.1-1.1-1.2-1.1-1.2-1.4
Locomotion distance, session 76.38.19.1-2.9-2.92.7-2.9-3.0-2.8-2.5-2.9
Stereotopy head waving bouts, day 70.50.60.90.70.7-0.60.70.80.50.91.0
Stereotopy head waving duration, day 70.30.40.50.70.6-0.40.70.70.40.60.7
Locomotion velocity, session 80.60.71.11.00.9-0.71.01.00.80.31.0
Locomotion distance, session 80.60.81.0-1.0-1.00.9-0.9-1.0-0.8-1.0-0.7
Degree of sensitization distance0.20.20.6-0.7-0.50.2-0.6-0.6-0.3-0.0-0.5
Degree of sensitization stereotypy0.20.20.3-0.5-0.50.5-0.5-0.5-0.6-0.2-0.0
Condit. Reinf. active minus inactive responses0.70.81.4-0.6-0.90.9-1.2-1.0-1.1-0.4-0.6
Condit. Reinf. active-inactive response ratio0.10.10.30.50.3-0.20.10.20.20.40.6
Condit. Reinf. active responses0.81.01.9-0.7-1.11.0-1.3-1.1-1.4-0.3-0.7
Condit. Reinf. inactive responses1.11.31.9-1.2-1.41.0-1.2-1.2-1.4-0.7-1.0
Incentive salience index mean1.51.82.7-1.2-1.51.3-1.7-1.5-1.6-0.7-1.0
Condit. Reinf. lever presses2.53.44.4-1.9-2.11.7-2.0-2.1-1.9-1.2-1.6
Time in familiar zone, hab. session 10.30.30.9-0.9-0.50.3-0.5-0.6-0.1-0.7-0.5
Time in novel zone, hab. session 13.33.25.22.31.8-1.41.72.01.31.72.0
Total zone transitions, hab. session 16.99.810.9-3.1-3.13.1-3.1-3.3-3.1-3.1-3.1
Total locomotion distance, hab. session 13.75.26.6-2.2-2.42.3-2.6-2.5-2.3-2.0-2.1
Locomotion velocity, hab. session 14.97.08.6-2.6-2.82.5-2.9-2.9-2.6-2.3-2.6
Time in familiar zone, hab. session 21.11.21.71.01.2-1.11.21.01.10.71.3
Time in novel zone, hab. session 20.10.10.3-0.1-0.40.3-0.5-0.3-0.3-0.3-0.5
Total zone transitions, hab. session 24.35.66.7-2.5-2.52.3-2.6-2.5-2.5-1.7-2.1
Total locomotion distance, hab. session 20.81.12.0-1.1-1.20.9-1.4-1.1-1.2-0.2-0.8
Locomotion velocity, hab. session 20.91.32.2-1.1-1.31.0-1.5-1.2-1.3-0.3-0.9
Novel to familiar place preference ratio0.20.20.9-0.2-0.20.4-0.6-0.3-0.3-0.9-0.1
Novelty place preference0.20.21.1-0.0-0.10.4-0.5-0.2-0.2-1.0-0.1
Time in novel zone, NPP test0.10.10.80.10.10.3-0.3-0.1-0.1-0.90.2
Total zone transitions, NPP test6.18.810.8-3.2-3.32.9-3.0-3.2-2.9-2.3-2.9
Total locomotion distance, NPP test1.92.63.6-1.6-1.91.5-1.9-1.8-1.5-1.0-1.6
Locomotion velocity, NPP test2.43.54.4-1.8-2.11.8-2.1-2.0-1.7-1.3-2.0
Pavlov. Cond. lever latency1.62.13.01.71.5-1.21.61.71.31.31.1
Pavlov. Cond. magazine entry latency0.10.20.3-0.5-0.30.4-0.5-0.5-0.5-0.20.4
Pavlov. Cond. change in total contacts3.63.84.8-2.2-2.01.9-2.2-2.2-2.0-1.6-1.4
Pavlov. Cond. index score0.81.11.7-1.2-1.00.9-1.3-1.3-1.1-0.9-0.4
Pavlov. Cond. latency score0.91.11.7-1.2-1.11.0-1.3-1.3-1.1-0.9-0.5
Pavlov. Cond. lever contacts2.83.34.7-2.2-2.01.6-1.9-2.1-1.7-1.6-1.5
Pavlov. Cond. magazine entry number0.50.61.10.90.7-0.71.00.90.80.50.1
Pavlov. Cond. intertrial magazine entries1.31.52.9-1.1-1.30.9-1.3-1.3-1.2-0.7-1.7
Pavlov. Cond. lever-magazine prob. diff.0.70.91.4-1.2-0.90.9-1.1-1.2-1.0-0.8-0.3
Pavlov. Cond. response bias0.80.91.6-1.3-1.00.9-1.1-1.2-0.9-0.8-0.3
Bone: apparent density1.72.84.21.81.7-1.61.11.81.51.72.0
Bone surface0.50.91.51.21.0-0.90.61.10.91.00.9
Bone volume1.42.33.31.81.5-1.51.11.71.31.61.5
Bone: connectivity density0.50.71.31.00.9-0.60.51.00.70.61.2
Bone: cortical apparent density5.67.310.2-2.6-2.52.7-2.4-2.5-2.8-3.2-2.9
Bone: cortical area0.30.50.80.70.8-0.70.70.70.90.50.4
Bone: cortical porosity0.40.40.70.90.6-0.60.60.60.60.70.4
Bone: cortical porosity0.20.20.50.70.5-0.50.40.40.40.70.2
Bone: cortical thickness0.10.20.40.40.7-0.30.60.40.6-0.4-0.1
Bone: cortical thickness0.30.41.1-0.5-0.51.1-0.4-0.3-0.6-1.0-0.1
Bone: cortical tissue density6.18.010.8-2.7-2.62.8-2.5-2.7-2.9-3.3-3.0
Bone: elastic displacement0.00.10.20.00.2-0.20.00.30.20.30.4
Bone: elastic work0.00.00.00.20.2-0.2-0.00.20.2-0.00.2
Bone: endosteal estimation0.10.20.90.10.1-0.40.10.30.31.00.6
Bone: endosteal perimeter0.20.51.50.50.4-0.70.40.50.71.20.6
Bone: final force0.20.30.50.50.5-0.60.10.40.50.70.6
Bone: final moment0.20.40.70.60.6-0.80.30.50.60.80.7
Bone: marrow area0.10.10.70.00.0-0.2-0.00.20.20.80.5
Bone: maximum diameter0.30.51.40.50.5-0.70.50.60.81.20.7
Bone: maximum force0.71.21.41.21.1-1.10.91.11.11.11.0
Bone: maximum moment0.81.41.61.31.2-1.21.01.21.21.21.1
Bone: minimum diameter0.00.00.10.20.2-0.20.10.10.00.4-0.2
Bone: periosteal estimation0.30.61.30.60.7-0.90.60.70.81.10.8
Bone: periosteal perimeter0.81.42.01.21.2-1.21.21.11.41.10.9
Bone: post-yield work0.60.81.10.91.1-0.91.11.00.90.50.6
Bone: stiffness0.10.10.20.20.3-0.40.10.20.40.40.2
Bone: tissue strength0.60.61.00.80.8-0.91.00.61.00.3-0.0
Bone: trabecular number0.40.61.40.80.6-0.6-0.00.80.31.11.2
Bone: trabecular spacing0.00.00.1-0.3-0.0-0.10.1-0.30.1-0.20.2
Bone: trabecular thickness3.64.46.52.52.3-1.82.32.52.11.51.6
Bone: trabecular tissue density0.20.30.8-0.9-0.50.30.1-0.4-0.1-0.4-0.9
Breakpoint value in progressive ratio session3.03.34.6-1.6-1.82.1-1.6-1.8-1.9-2.1-1.5
Distance traveled before self-admin2.42.54.5-2.1-1.81.3-2.0-1.8-1.4-0.8-1.0
Distance traveled after self-admin0.30.31.10.20.5-0.50.20.50.50.91.0
Delta time in closed arm before/after self-admin0.20.10.40.60.4-0.30.30.40.3-0.3-0.2
Delta time in open arm before/after self-admin0.00.00.1-0.1-0.10.2-0.0-0.00.1-0.3-0.2
Diff in mean of infusions in LGA sessions1.21.42.5-1.3-1.31.1-1.6-1.2-1.3-0.6-0.7
Extinction: sum of active levers before priming1.21.22.7-1.0-1.01.0-1.1-1.0-0.8-1.2-1.6
Active lever presses in extinction session 60.20.20.90.40.2-0.00.30.50.10.40.9
Delta distance traveled before/after self-admin3.03.24.12.01.9-1.61.92.01.71.41.6
Delta ambulatory time before/after self-admin3.13.44.52.12.0-1.81.82.01.71.51.7
Time in closed arm before self-admin3.03.44.52.02.1-1.91.81.91.81.61.4
Time in closed arm after self-admin3.13.25.12.32.2-2.01.72.01.81.10.8
Time in open arm before self-admin0.70.81.0-1.0-0.90.7-0.8-1.0-0.7-1.0-0.8
Time in open arm after self-admin0.60.71.2-1.1-0.90.8-0.6-1.0-0.5-1.0-0.6
Sum of active levers in priming session hrs 5-64.94.86.3-2.1-2.32.5-2.2-2.1-2.4-2.0-2.0
Time to tail flick, vehicle, before self-admin1.31.32.1-1.0-1.01.2-1.1-1.2-1.3-1.4-0.8
Time to tail flick, vehicle, after self-admin0.70.81.11.01.0-0.90.91.01.10.60.3
Time to tail flick, test, before self-admin0.80.81.61.21.0-0.61.01.00.60.30.8
Time to tail flick, test, after self-admin0.60.61.21.11.0-0.50.90.90.60.10.6
Delta time to tail flick, vehicle, before/after SA2.92.83.81.71.8-1.71.81.82.01.41.2
Delta time to tail flick, test, before/after SA0.40.40.5-0.7-0.60.7-0.5-0.6-0.5-0.6-0.5
Ambulatory time before self-admin1.71.73.4-1.8-1.51.0-1.7-1.6-0.9-0.6-0.9
Ambulatory time after self-admin0.50.61.10.60.7-0.80.40.80.81.10.9
Total heroin consumption0.60.72.1-0.6-0.61.0-0.6-0.8-0.8-1.5-0.3
Area under the delay curve0.00.00.1-0.2-0.10.30.1-0.0-0.0-0.3-0.3
Delay disc. indifference point, 0s delay0.10.10.5-0.2-0.00.10.2-0.10.3-0.7-0.7
Delay disc. indifference point, 16s delay1.11.11.81.11.2-0.81.31.21.00.71.0
Delay disc. indifference point, 2s delay0.10.10.6-0.3-0.30.2-0.3-0.3-0.0-0.3-0.7
Delay disc. indifference point, 24s delay0.70.60.9-0.8-0.80.9-0.8-0.8-0.9-0.7-0.6
Delay disc. indifference point, 4s delay1.31.32.8-0.9-1.01.4-0.7-0.9-0.9-1.7-1.5
Delay disc. indifference point, 8s delay0.10.10.2-0.3-0.30.4-0.1-0.2-0.3-0.3-0.4
Delay discount exponential model param0.10.10.20.30.2-0.40.10.10.20.40.3
Delay discount hyperbolic model param0.20.20.40.30.3-0.50.20.20.20.60.5
Fecal boli incidents, locomotor time 13.74.15.12.22.1-1.81.92.11.82.02.2
Change in fecal boli incidents, locomotor task2.42.22.9-1.5-1.31.3-1.5-1.4-1.4-1.7-1.7
Time >=10cm from walls, locomotor time 10.20.20.3-0.5-0.20.1-0.5-0.5-0.0-0.5-0.3
Bouts of movement, locomotor time 10.20.20.50.60.6-0.40.70.60.30.30.3
Total resting periods, locomotor time 10.60.61.01.01.0-0.71.00.90.60.50.6
Rest time, locomotor task time 10.10.10.30.30.2-0.30.40.40.30.50.2
Distance moved, locomotor task time 12.12.33.4-1.6-1.51.4-1.8-1.8-1.5-1.2-1.1
Vertical activity count, locomotor time 10.60.61.1-0.8-0.70.6-0.9-1.0-0.6-0.9-0.4
Time >=10cm from walls, locomotor time 20.50.60.8-0.9-0.70.6-0.7-0.9-0.5-0.9-0.8
Bouts of movement, locomotor time 20.10.10.20.00.2-0.4-0.10.10.40.40.2
Total resting periods, locomotor time 20.10.10.3-0.00.2-0.5-0.10.10.50.40.2
Rest time, locomotor task time 20.70.81.7-0.7-0.90.8-0.5-0.8-0.8-1.1-1.3
Distance moved, locomotor task time 20.10.10.3-0.2-0.30.5-0.3-0.2-0.4-0.4-0.2
Vertical activity count, locomotor time 20.00.00.1-0.2-0.10.2-0.3-0.2-0.1-0.1-0.1
Weight adjusted by age0.20.21.2-0.1-0.20.5-0.2-0.1-0.1-1.1-0.5
Seeking ratio, delayed vs. immediate footshock1.51.72.51.61.6-1.41.41.41.40.70.5
Locomotion in novel chamber0.20.30.7-0.6-0.30.1-0.8-0.6-0.1-0.8-0.4
Locomotion in novel chamber post-restriction1.01.22.80.71.0-1.60.70.71.71.20.3
Progressive ratio0.10.10.3-0.20.0-0.60.1-0.10.50.20.0
Food seeking constrained by brief footshock0.20.21.00.10.1-0.20.20.2-0.11.00.9
Seeking ratio, punishment vs. effort0.30.31.0-0.3-0.50.9-0.6-0.3-1.0-0.3-0.2
Run reversals in cocaine runway, females0.20.20.4-0.0-0.20.6-0.1-0.2-0.5-0.7-0.6
Run reversals in cocaine runway, males0.90.81.90.30.7-1.40.70.51.40.80.9
Latency to leave start box in cocaine runway5.86.38.22.92.7-2.62.32.82.62.12.0
Latency to leave start box in cocaine runway, F8.49.211.83.43.3-3.13.03.33.22.52.2
Latency to leave start box in cocaine runway, M0.40.31.00.30.4-0.6-0.20.50.41.00.8
Cd content in liver0.40.50.9-0.9-0.50.2-0.9-0.9-0.2-0.8-0.5
Co content in liver0.00.00.1-0.30.0-0.3-0.2-0.20.00.20.1
Cu content in liver8.510.215.4-3.5-3.52.9-3.9-3.3-3.6-1.6-2.8
Fe content in liver2.02.43.1-1.5-1.71.4-1.8-1.7-1.6-1.2-1.7
K content in liver0.60.61.0-0.8-0.80.4-1.0-0.6-0.80.5-0.9
Mg content in liver2.62.64.1-1.7-1.71.2-2.0-1.6-1.6-0.7-2.0
Mn content in liver3.64.25.1-2.0-2.22.3-1.9-2.1-2.0-1.8-1.9
Na content in liver0.30.30.8-0.3-0.60.3-0.8-0.3-0.70.9-0.2
Rb content in liver0.20.31.0-0.5-0.40.2-0.7-0.5-1.0-0.0-0.1
Se content in liver0.10.20.50.10.3-0.60.10.20.60.70.2
Sr content in liver1.31.22.9-1.0-0.91.1-0.5-0.9-0.4-1.5-1.7
Zn content in liver0.20.30.8-0.6-0.5-0.1-0.9-0.4-0.20.2-0.7