Hub : Genes

ENSRNOG00000069592

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000069592 0.27 0.16 0.0e+00 0.19 0.17 0.17 0.18 2.8e-20 2.9e-18 1.8e-18 7.9e-20
2 BLA gene expression ENSRNOG00000069592 0.61 0.08 0.0e+00 0.53 0.52 0.54 0.54 6.1e-33 2.0e-32 1.1e-33 1.4e-33
3 Brain gene expression ENSRNOG00000069592 0.8 0.07 0.0e+00 0.66 0.67 0.68 0.68 3.4e-81 4.2e-83 3.2e-86 3.6e-86
4 IL gene expression ENSRNOG00000069592 0.46 0.15 3.0e-09 0.26 0.31 0.21 0.27 6.0e-07 3.5e-08 7.7e-06 3.9e-07
5 LHb gene expression ENSRNOG00000069592 0.31 0.14 7.4e-06 0.17 0.21 0.07 0.05 5.9e-05 1.1e-05 1.1e-02 2.1e-02
6 NAcc gene expression ENSRNOG00000069592 0.14 0.09 1.3e-11 0.15 0.15 0.14 0.14 3.6e-11 5.4e-11 9.1e-11 6.4e-11
7 OFC gene expression ENSRNOG00000069592 0.69 0.11 0.0e+00 0.48 0.53 0.54 0.54 4.1e-13 8.8e-15 2.5e-15 3.4e-15
8 PL gene expression ENSRNOG00000069592 0.52 0.09 0.0e+00 0.48 0.49 0.5 0.49 9.6e-41 2.4e-42 1.4e-42 1.7e-42

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail16.754.362.8-7.1-7.2-6.9-7.9-7.6-7.4-7.0-7.7
BMI without tail0.91.92.5-1.4-1.3-1.2-1.6-1.4-1.3-1.1-1.5
Body weight0.94.05.3-2.3-1.9-2.0-2.0-1.9-1.8-1.8-2.1
Epididymis fat weight0.10.20.7-0.3-0.2-0.1-0.8-0.4-0.3-0.4-0.4
Glucose0.81.21.6-1.3-1.0-1.2-1.0-1.1-0.8-1.1-1.0
Heart weight0.81.11.9-1.0-0.9-0.9-1.4-1.1-0.9-1.1-1.0
Left kidney weight0.00.00.1-0.30.0-0.10.00.10.1-0.10.0
Right kidney weight0.51.31.9-1.4-1.0-1.2-1.0-1.1-1.0-1.3-1.1
Tail length15.948.152.36.66.96.67.27.27.26.67.2
Length with tail7.527.532.94.65.24.75.75.65.55.05.5
Length without tail0.00.00.1-0.2-0.0-0.20.30.10.10.00.1
Liver weight, left0.71.21.70.71.21.11.01.31.31.01.1
Liver weight, right0.40.71.10.30.90.60.91.11.00.90.9
Parametrial fat weight0.20.30.50.70.60.70.10.60.50.40.5
Retroperitoneal fat weight0.10.40.6-0.6-0.7-0.7-0.7-0.7-0.6-0.6-0.7
Intraocular pressure1.31.81.91.41.31.41.31.31.31.41.3
Extensor digitorum longus weight1.04.05.8-2.4-2.0-2.1-1.8-1.8-1.9-1.9-2.1
Soleus weight1.75.05.9-2.4-2.3-2.3-2.0-2.2-2.3-2.0-2.2
Tibialis anterior weight0.00.00.2-0.40.10.00.00.20.10.1-0.2
Tibia length0.41.21.6-1.2-1.1-1.2-1.0-1.2-0.9-1.2-1.0
Number of licking bursts1.61.92.91.71.41.51.11.11.41.31.4
Food consumed during 24 hour testing period1.82.22.41.41.51.51.51.61.51.51.5
Times rat made contact with spout1.01.11.81.31.01.10.91.00.90.91.1
Mean time between licks in bursts0.50.71.0-0.4-0.9-0.8-0.8-1.0-1.0-0.9-0.6
Mean num. licks in bursts0.10.20.3-0.5-0.4-0.5-0.3-0.2-0.5-0.4-0.4
Std. dev. time between licks in bursts0.60.70.9-0.7-0.9-0.9-0.5-1.0-0.9-0.7-0.8
Water consumed over 24 hours0.10.10.20.40.30.40.20.20.30.20.3
Indifference point 0 sec1.52.53.1-1.4-1.5-1.5-1.7-1.6-1.5-1.8-1.6
Indifference point AUC0.10.10.40.20.10.10.60.20.30.40.3
Indifference point function ln k0.00.00.00.00.10.1-0.00.1-0.1-0.00.0
Indifference point function log k0.00.00.00.00.10.1-0.00.1-0.1-0.00.0
Delay discounting total patch changes 0 sec1.62.63.4-1.4-1.5-1.6-1.8-1.7-1.5-1.9-1.6
Delay discounting total patch changes 12 sec0.00.00.10.30.10.1-0.2-0.10.2-0.10.1
Delay discounting total patch changes 18 sec2.02.63.3-1.5-1.6-1.7-1.7-1.8-1.4-1.8-1.6
Delay discounting total patch changes 24 sec1.31.62.1-1.2-1.2-1.2-1.4-1.2-1.1-1.4-1.3
Delay discounting total patch changes 6 sec1.01.51.7-1.1-1.3-1.3-1.2-1.3-1.1-1.2-1.2
Delay discounting time to switch 0 sec0.20.20.30.50.60.50.40.40.60.40.5
Delay discounting water rate 0 sec2.43.84.7-2.2-2.1-2.0-1.7-1.8-2.1-1.6-2.0
Delay discounting water rate 12 sec0.91.41.8-1.3-1.2-1.2-1.1-1.0-1.3-1.1-1.2
Delay discounting water rate 18 sec0.00.00.10.1-0.2-0.0-0.4-0.1-0.2-0.2-0.2
Delay discounting water rate 24 sec1.52.12.6-1.3-1.5-1.3-1.5-1.5-1.6-1.4-1.5
Delay discounting water rate 6 sec0.20.40.6-0.8-0.6-0.5-0.6-0.4-0.7-0.4-0.7
Locomotor activity0.10.10.3-0.2-0.3-0.3-0.4-0.6-0.2-0.1-0.4
Locomotor testing distance0.20.30.7-0.4-0.3-0.3-0.7-0.8-0.3-0.4-0.6
Locomotor testing rearing0.00.10.2-0.4-0.1-0.2-0.3-0.4-0.10.0-0.4
Light reinforcement 10.00.00.1-0.0-0.00.0-0.4-0.3-0.1-0.3-0.2
Light reinforcement 20.50.71.00.90.90.90.70.71.00.70.8
Reaction time number correct1.42.02.7-1.2-1.3-1.3-1.6-1.5-1.4-1.6-1.3
Reaction time mean minus median2.22.84.41.41.51.42.11.81.51.91.7
Reaction time mean minus median AUC3.34.25.41.81.91.92.32.21.92.22.1
Reaction time num false alarms0.60.91.11.00.90.91.00.90.91.00.9
Reaction time num false alarms AUC0.71.01.21.10.91.01.10.91.01.11.0
Reaction time trials correct on left1.42.02.7-1.2-1.3-1.3-1.6-1.5-1.4-1.6-1.3
Reaction time trials on left1.31.92.5-1.2-1.3-1.2-1.5-1.4-1.4-1.6-1.3
Reaction time mean1.31.83.40.91.11.01.91.51.21.71.3
Reaction time mean AUC1.62.24.21.01.21.12.01.61.21.91.4
Median of all reaction times0.50.71.50.40.60.51.21.00.71.20.8
Reaction time omissions1.31.72.11.31.21.31.51.31.21.41.3
Reaction time false alarm rate1.62.22.61.61.41.41.61.41.41.61.5
Reaction time premature initiation rate0.30.40.70.70.80.70.30.50.80.30.6
Reaction time premature initiations0.00.10.30.00.10.1-0.4-0.20.1-0.5-0.1
Std. dev. reaction times2.23.05.41.41.41.42.31.91.52.11.7
Reaction time trials completed1.31.92.5-1.2-1.3-1.2-1.5-1.4-1.4-1.6-1.3
Reaction time trials AUC1.42.02.6-1.3-1.3-1.2-1.6-1.4-1.4-1.6-1.3
Social response proportion1.61.82.21.21.31.31.51.51.11.41.3
Social responses0.10.10.2-0.2-0.3-0.1-0.4-0.2-0.5-0.2-0.4
Social time0.10.10.30.6-0.10.2-0.4-0.4-0.3-0.2-0.2
Conditioned locomotion1.31.62.6-0.8-1.1-1.0-1.6-1.4-1.1-1.6-1.1
Cocaine response after cond. corrected5.96.67.8-2.4-2.5-2.4-2.8-2.7-2.4-2.6-2.7
Cocaine response after cond. not corrected3.64.05.1-1.7-2.0-1.9-2.3-2.1-2.0-2.0-2.1
Cocaine response before conditioning2.32.93.71.91.61.71.71.81.41.61.8
Saline control response0.20.20.90.90.40.6-0.4-0.20.3-0.10.3
Condit. Reinf. active minus inactive responses0.20.30.50.60.60.70.10.50.50.40.4
Condit. Reinf. active-inactive response ratio0.40.40.80.90.70.9-0.00.40.60.50.4
Condit. Reinf. active responses0.10.20.20.30.50.50.20.40.40.40.4
Condit. Reinf. inactive responses0.00.00.1-0.4-0.1-0.20.30.0-0.10.10.0
Condit. Reinf. lever presses0.30.40.80.20.60.40.90.70.70.70.6
Condit. Reinf. lever reinforcers received0.10.20.30.20.50.50.20.50.50.40.4
Pavlov. Cond. lever latency1.92.64.02.01.61.81.31.61.41.61.6
Pavlov. Cond. magazine entry latency0.40.40.60.50.60.50.80.70.70.40.7
Pavlov. Cond. change in total contacts0.50.71.4-1.2-0.9-1.1-0.5-0.8-0.8-0.8-0.8
Pavlov. Cond. index score0.40.61.0-1.0-0.7-0.9-0.5-0.7-0.6-0.9-0.7
Pavlov. Cond. latency score0.20.30.5-0.7-0.5-0.7-0.3-0.4-0.4-0.7-0.5
Pavlov. Cond. lever contacts1.31.82.7-1.7-1.3-1.5-1.0-1.3-1.2-1.3-1.3
Pavlov. Cond. magazine entry number0.00.10.20.40.20.4-0.10.00.10.40.1
Pavlov. Cond. intertrial magazine entries1.92.53.21.71.51.61.61.41.41.81.5
Pavlov. Cond. lever-magazine prob. diff.0.60.71.2-1.1-0.8-1.0-0.6-0.8-0.7-1.0-0.8
Pavlov. Cond. response bias0.81.11.8-1.3-1.0-1.2-0.8-1.0-0.9-1.1-1.0
Conditioned reinforcement - actives0.40.40.50.50.70.70.50.50.70.70.6
Conditioned reinforcement - inactives0.30.30.50.70.60.70.40.30.60.60.6
Conditioned locomotion0.00.10.20.20.10.2-0.4-0.30.0-0.2-0.1
Intermittent access intake day 1-15 change0.90.91.1-1.0-0.8-0.8-1.1-1.0-0.8-1.0-0.9
Intermittent access intake escalation0.40.40.6-0.8-0.5-0.6-0.7-0.7-0.5-0.7-0.7
Intermittent access intake escalation 20.80.81.3-0.9-0.7-0.7-1.1-0.9-0.7-1.0-0.9
Intermitt. access day 1 inactive lever presses0.00.00.00.1-0.00.1-0.1-0.0-0.10.2-0.1
Intermitt. access day 15 inactive lever presses1.82.02.3-1.4-1.5-1.5-1.2-1.4-1.4-1.3-1.4
Intermitt. access escalation Index0.10.10.10.20.40.30.30.30.40.30.2
Intermittent access day 1 total infusions1.21.31.51.21.11.11.11.21.21.21.2
Intermittent access day 15 total infusions0.70.81.00.80.90.90.80.81.00.80.9
Intermittent access terminal intake (last 3 days)0.30.30.50.50.70.70.40.50.70.50.6
Intermittent access total infusions0.40.50.60.70.70.70.50.60.80.70.7
Intermittent access day 1 locomotion3.03.13.61.91.71.71.71.71.81.71.8
Intermittent access day 15 total locomotion1.01.11.31.11.11.10.90.91.21.01.1
Intermittent access total locomotion1.31.51.71.31.21.21.11.11.31.21.3
Intermittent access standard deviation0.60.61.0-0.7-0.6-0.7-1.0-0.9-0.6-0.9-0.8
Cocaine induced anxiety0.00.10.10.30.30.4-0.00.00.30.20.1
Post-drug Anxiety1.81.92.41.51.51.51.11.21.51.31.4
Baseline Anxiety0.00.00.0-0.0-0.0-0.1-0.2-0.0-0.0-0.20.0
Lifetime Intake0.40.40.50.60.70.70.60.70.70.70.7
Incentive Sensitization - Responses0.50.50.80.80.70.80.50.50.70.90.7
Incentive Sensitization - Breakpoint0.20.20.40.50.50.60.20.30.40.70.4
Progressive ratio test 1 active lever presses1.11.11.21.01.11.10.91.11.11.11.0
Progressive ratio test 1 breakpoint1.21.21.41.11.21.21.01.11.21.11.1
Progressive ratio test 1 inactive lever presses0.40.40.6-0.7-0.7-0.6-0.5-0.7-0.7-0.4-0.7
Progressive ratio test 2 active lever presses1.82.02.31.51.41.51.21.21.41.51.4
Progressive ratio test 2 breakpoint1.11.21.51.21.11.20.80.91.11.21.1
Progressive ratio test 2 inactive lever presses0.10.10.30.30.40.40.30.10.40.60.4
Total sessions with >9 infusions0.91.01.31.00.91.01.11.01.00.91.0
Short access day 1 total inactive lever presses0.10.10.10.30.30.30.30.40.30.30.3
Short access day 10 total inactive lever presses0.30.40.7-0.4-0.5-0.5-0.8-0.6-0.6-0.6-0.6
Short access day 1 total infusions0.00.00.20.10.00.00.50.20.10.20.1
Short access day 10 total infusions0.20.20.30.30.50.40.40.40.50.40.5
Short access total infusions0.00.00.10.10.00.00.20.10.10.00.1
Short access day 1 locomotion0.00.00.00.10.10.00.10.00.1-0.10.1
Short access day 10 total locomotion1.41.51.71.31.21.21.21.11.31.21.3
Short access total locomotion0.40.40.50.70.60.60.70.50.70.40.7
Compulsive drug intake5.35.36.72.22.12.22.42.62.02.52.3
One hour access (0.3 mA shock)0.80.91.10.90.91.00.81.00.91.10.9
One hour access (shock baseline)0.60.71.3-0.8-0.6-0.6-1.1-1.0-0.6-0.8-0.9
Number of responses in last shaping day1.81.82.3-1.3-1.3-1.3-1.4-1.5-1.3-1.5-1.3
Context. condit. distance diff. score1.01.21.6-1.3-1.1-1.1-1.0-1.1-1.1-1.0-1.2
Locomotion velocity, session 10.20.20.20.40.50.50.40.20.50.40.4
Locomotion distance, session 15.57.28.12.62.72.62.82.62.72.72.8
Locomotion velocity, session 21.21.41.91.21.11.01.41.21.11.11.3
Locomotion distance, session 27.110.211.23.43.13.23.33.03.13.23.3
Locomotion velocity, session 30.60.61.0-0.9-0.9-1.0-0.5-0.8-0.8-0.8-0.7
Locomotion distance, session 31.21.31.41.11.11.11.21.11.21.11.2
Stereotopy head waving bouts, day 34.45.36.3-2.3-2.4-2.4-2.0-2.2-2.5-2.1-2.3
Stereotopy head waving duration, day 33.03.64.1-2.0-1.9-2.0-1.7-1.9-1.9-1.8-1.9
Locomotion velocity, session 71.61.72.71.11.21.11.61.21.41.41.4
Locomotion distance, session 77.29.210.13.03.02.93.23.03.03.13.1
Stereotopy head waving bouts, day 70.60.60.7-0.8-0.8-0.8-0.7-0.7-0.8-0.8-0.8
Stereotopy head waving duration, day 70.40.50.7-0.8-0.7-0.8-0.7-0.6-0.7-0.8-0.7
Locomotion velocity, session 80.91.11.6-1.3-1.1-1.2-0.6-1.0-1.1-0.9-1.1
Locomotion distance, session 80.50.80.90.90.90.91.00.90.90.90.9
Degree of sensitization distance0.40.40.50.70.60.60.70.60.70.70.7
Degree of sensitization stereotypy0.10.10.20.40.40.40.20.40.30.30.3
Condit. Reinf. active minus inactive responses1.01.11.41.01.01.01.01.11.01.21.1
Condit. Reinf. active-inactive response ratio0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.2-0.0-0.2
Condit. Reinf. active responses1.21.41.61.21.21.21.11.21.11.31.2
Condit. Reinf. inactive responses1.31.62.01.41.41.41.01.21.31.01.3
Incentive salience index mean2.02.42.71.61.51.61.51.51.51.61.6
Condit. Reinf. lever presses3.14.15.32.32.02.21.81.92.01.92.0
Time in familiar zone, hab. session 10.20.20.50.70.40.60.00.30.30.30.4
Time in novel zone, hab. session 13.33.25.1-2.3-1.8-2.0-1.4-1.6-1.7-1.6-1.8
Total zone transitions, hab. session 16.99.79.83.13.13.13.13.13.13.13.1
Total locomotion distance, hab. session 14.26.06.62.32.42.42.52.52.52.62.4
Locomotion velocity, hab. session 15.98.58.72.92.92.92.92.92.93.02.9
Time in familiar zone, hab. session 21.81.92.3-1.2-1.4-1.3-1.5-1.3-1.5-1.4-1.4
Time in novel zone, hab. session 20.40.40.60.40.60.50.70.50.80.60.6
Total zone transitions, hab. session 25.16.66.92.62.62.62.52.52.62.52.6
Total locomotion distance, hab. session 21.52.02.31.31.51.41.41.31.51.41.5
Locomotion velocity, hab. session 21.72.22.61.31.61.51.51.41.61.51.5
Novel to familiar place preference ratio0.20.20.3-0.10.50.40.20.50.60.50.2
Novelty place preference0.10.10.2-0.30.40.20.20.40.40.40.1
Time in novel zone, NPP test0.00.10.2-0.50.2-0.00.00.20.20.3-0.1
Total zone transitions, NPP test7.010.110.93.33.23.23.13.03.23.03.3
Total locomotion distance, NPP test3.14.34.82.02.12.12.11.82.22.02.1
Locomotion velocity, NPP test3.65.25.72.22.32.22.32.12.42.22.4
Pavlov. Cond. lever latency1.62.02.6-1.6-1.4-1.5-1.3-1.2-1.4-1.5-1.4
Pavlov. Cond. magazine entry latency0.10.10.30.10.10.20.30.3-0.00.50.1
Pavlov. Cond. change in total contacts3.53.74.42.01.92.01.82.01.72.11.9
Pavlov. Cond. index score0.81.01.81.00.91.01.10.90.81.30.9
Pavlov. Cond. latency score0.91.11.81.00.91.11.21.00.81.40.9
Pavlov. Cond. lever contacts2.93.44.32.11.82.01.81.61.81.91.8
Pavlov. Cond. magazine entry number0.40.51.1-0.6-0.6-0.7-0.8-0.8-0.5-1.1-0.6
Pavlov. Cond. intertrial magazine entries1.92.33.31.81.71.71.01.41.71.01.6
Pavlov. Cond. lever-magazine prob. diff.0.60.71.40.90.70.91.00.80.61.20.7
Pavlov. Cond. response bias0.60.71.10.90.80.90.80.80.61.10.7
Bone: apparent density1.32.13.5-1.9-1.2-1.4-1.7-1.3-1.1-1.4-1.6
Bone surface0.30.61.1-1.1-0.6-0.8-0.9-0.6-0.5-0.7-0.8
Bone volume0.91.42.7-1.6-1.0-1.2-1.3-1.1-0.8-1.2-1.2
Bone: connectivity density0.50.81.7-1.3-0.6-0.8-1.2-0.6-0.6-0.9-1.0
Bone: cortical apparent density4.86.310.02.02.22.13.22.62.32.82.5
Bone: cortical area0.20.40.4-0.6-0.6-0.7-0.6-0.7-0.5-0.6-0.6
Bone: cortical porosity0.20.20.3-0.3-0.5-0.4-0.5-0.6-0.5-0.5-0.4
Bone: cortical porosity0.10.10.2-0.1-0.3-0.2-0.4-0.4-0.2-0.4-0.2
Bone: cortical thickness0.20.30.5-0.6-0.7-0.70.0-0.4-0.6-0.2-0.4
Bone: cortical thickness0.20.20.7-0.30.30.10.80.60.30.80.3
Bone: cortical tissue density5.36.910.72.12.42.33.32.82.42.92.6
Bone: elastic displacement0.00.00.0-0.2-0.1-0.1-0.1-0.1-0.10.0-0.1
Bone: elastic work0.00.00.1-0.20.20.00.00.00.30.10.0
Bone: endosteal estimation0.00.10.2-0.20.20.1-0.4-0.10.3-0.2-0.1
Bone: endosteal perimeter0.10.20.7-0.2-0.2-0.2-0.8-0.4-0.1-0.7-0.4
Bone: final force0.00.00.1-0.30.0-0.1-0.3-0.20.2-0.1-0.1
Bone: final moment0.10.10.2-0.4-0.2-0.3-0.4-0.40.0-0.2-0.3
Bone: marrow area0.00.10.2-0.10.30.2-0.30.00.4-0.1-0.0
Bone: maximum diameter0.20.30.8-0.3-0.5-0.4-0.9-0.6-0.4-0.8-0.6
Bone: maximum force0.40.60.9-1.0-0.7-0.8-0.9-0.9-0.4-0.8-0.8
Bone: maximum moment0.50.91.2-1.1-0.8-1.0-1.0-1.0-0.6-0.9-0.9
Bone: minimum diameter0.00.00.1-0.00.20.0-0.30.00.3-0.30.1
Bone: periosteal estimation0.10.30.7-0.5-0.3-0.4-0.8-0.6-0.2-0.7-0.5
Bone: periosteal perimeter0.81.32.1-0.9-1.0-1.0-1.4-1.2-0.9-1.3-1.1
Bone: post-yield work0.70.91.2-1.1-0.9-1.0-0.8-1.0-0.8-0.9-1.0
Bone: stiffness0.00.00.1-0.10.1-0.0-0.2-0.10.3-0.0-0.0
Bone: tissue strength0.60.60.9-0.5-0.9-0.8-0.9-0.8-0.8-0.9-0.7
Bone: trabecular number0.20.20.7-0.8-0.1-0.3-0.8-0.2-0.0-0.4-0.5
Bone: trabecular spacing0.00.00.10.2-0.2-0.00.1-0.3-0.30.1-0.1
Bone: trabecular thickness3.54.35.7-2.4-2.0-2.3-1.9-1.9-1.8-2.1-2.0
Bone: trabecular tissue density0.10.10.40.7-0.00.10.60.1-0.00.20.4
Breakpoint value in progressive ratio session1.61.82.81.51.21.31.31.71.11.41.3
Distance traveled before self-admin3.03.33.81.91.92.01.51.81.81.91.7
Distance traveled after self-admin0.40.40.8-0.9-0.5-0.5-0.9-0.6-0.5-0.4-0.8
Delta time in closed arm before/after self-admin0.10.10.1-0.3-0.3-0.3-0.2-0.2-0.3-0.2-0.3
Delta time in open arm before/after self-admin0.00.00.10.00.0-0.00.20.10.10.10.1
Diff in mean of infusions in LGA sessions1.51.72.71.11.21.31.41.41.11.71.2
Extinction: sum of active levers before priming1.41.41.71.21.21.21.11.31.21.11.3
Active lever presses in extinction session 60.30.30.7-0.6-0.7-0.6-0.3-0.3-0.8-0.2-0.7
Delta distance traveled before/after self-admin3.74.04.9-2.2-1.9-2.0-1.9-2.0-1.9-1.9-2.1
Delta ambulatory time before/after self-admin3.63.94.6-2.1-1.9-1.9-2.0-2.0-1.9-1.9-2.0
Time in closed arm before self-admin2.73.03.5-1.9-1.7-1.8-1.6-1.8-1.7-1.6-1.7
Time in closed arm after self-admin2.52.63.0-1.7-1.6-1.7-1.5-1.7-1.5-1.6-1.5
Time in open arm before self-admin0.50.50.80.90.80.90.30.70.70.50.7
Time in open arm after self-admin0.30.40.60.80.50.70.60.60.50.60.6
Sum of active levers in priming session hrs 5-64.44.35.61.92.12.02.12.42.02.02.1
Time to tail flick, vehicle, before self-admin0.90.91.60.70.70.81.31.10.61.20.8
Time to tail flick, vehicle, after self-admin0.60.60.7-0.8-0.7-0.8-0.9-0.8-0.6-0.8-0.7
Time to tail flick, test, before self-admin1.11.11.5-1.1-1.2-1.2-0.8-0.9-1.2-1.0-1.0
Time to tail flick, test, after self-admin1.01.01.6-1.3-1.2-1.2-0.7-0.8-1.1-0.7-1.0
Delta time to tail flick, vehicle, before/after SA2.72.63.2-1.6-1.4-1.6-1.8-1.8-1.4-1.8-1.6
Delta time to tail flick, test, before/after SA0.20.20.30.20.40.40.60.60.50.60.4
Ambulatory time before self-admin2.32.43.01.71.71.71.21.41.71.61.5
Ambulatory time after self-admin0.50.51.1-0.9-0.5-0.5-1.0-0.7-0.6-0.6-0.8
Total heroin consumption0.10.10.30.30.20.30.20.50.10.40.1
Area under the delay curve0.00.00.0-0.10.10.00.00.1-0.0-0.00.1
Delay disc. indifference point, 0s delay0.00.00.10.20.30.30.1-0.00.20.00.3
Delay disc. indifference point, 16s delay1.71.72.1-1.4-1.3-1.3-1.3-1.2-1.4-1.3-1.3
Delay disc. indifference point, 2s delay0.20.20.40.30.70.60.20.40.60.20.6
Delay disc. indifference point, 24s delay0.60.60.80.70.70.70.90.80.60.90.7
Delay disc. indifference point, 4s delay0.80.81.20.51.00.91.01.10.80.91.0
Delay disc. indifference point, 8s delay0.00.00.10.10.30.20.20.20.20.20.3
Delay discount exponential model param0.00.00.00.1-0.2-0.1-0.1-0.2-0.1-0.1-0.2
Delay discount hyperbolic model param0.10.10.10.0-0.3-0.2-0.2-0.3-0.2-0.2-0.3
Fecal boli incidents, locomotor time 14.24.65.8-2.4-2.3-2.4-1.8-2.0-2.2-1.9-2.2
Change in fecal boli incidents, locomotor task2.42.32.51.41.61.61.41.51.51.61.6
Time >=10cm from walls, locomotor time 10.10.10.20.20.50.50.00.20.40.40.2
Bouts of movement, locomotor time 10.30.30.6-0.6-0.8-0.80.0-0.4-0.7-0.2-0.5
Total resting periods, locomotor time 10.70.81.2-0.9-1.1-1.1-0.3-0.8-1.1-0.6-0.8
Rest time, locomotor task time 10.10.10.10.0-0.2-0.2-0.2-0.3-0.3-0.4-0.1
Distance moved, locomotor task time 12.12.32.81.41.61.61.31.71.61.61.4
Vertical activity count, locomotor time 10.50.60.80.70.70.80.70.80.70.90.7
Time >=10cm from walls, locomotor time 20.40.50.60.80.70.70.50.60.70.70.6
Bouts of movement, locomotor time 20.00.00.0-0.20.20.1-0.10.00.20.10.0
Total resting periods, locomotor time 20.00.00.0-0.10.20.2-0.2-0.00.20.00.1
Rest time, locomotor task time 20.40.51.01.00.70.80.40.60.60.40.7
Distance moved, locomotor task time 20.10.10.4-0.00.20.10.60.40.20.50.3
Vertical activity count, locomotor time 20.20.20.40.00.30.20.70.40.40.60.4
Weight adjusted by age0.00.00.1-0.1-0.0-0.00.30.3-0.10.3-0.0
Seeking ratio, delayed vs. immediate footshock1.51.72.2-1.2-1.2-1.2-1.4-1.4-1.3-1.5-1.3
Locomotion in novel chamber0.20.30.50.30.70.70.00.50.60.40.4
Locomotion in novel chamber post-restriction0.40.41.5-0.0-0.1-0.1-1.2-0.90.0-1.0-0.4
Progressive ratio0.10.20.50.20.30.3-0.7-0.30.3-0.5-0.0
Food seeking constrained by brief footshock0.10.10.2-0.3-0.3-0.2-0.4-0.3-0.4-0.3-0.4
Seeking ratio, punishment vs. effort0.30.41.10.30.20.21.00.80.10.90.5
Run reversals in cocaine runway, females0.10.10.2-0.10.10.00.40.30.20.30.2
Run reversals in cocaine runway, males0.60.51.5-0.1-0.4-0.3-1.2-1.0-0.5-1.0-0.6
Latency to leave start box in cocaine runway5.35.87.8-2.8-2.2-2.5-2.5-2.2-2.1-2.5-2.4
Latency to leave start box in cocaine runway, F8.49.211.2-3.1-2.8-3.0-3.3-2.9-2.7-3.3-3.0
Latency to leave start box in cocaine runway, M0.10.10.4-0.6-0.1-0.3-0.10.1-0.00.2-0.2
Cd content in liver0.40.40.80.90.80.9-0.20.40.90.20.4
Co content in liver0.00.00.10.30.10.20.1-0.00.10.20.1
Cu content in liver12.114.515.73.93.73.83.83.83.64.03.9
Fe content in liver2.93.54.12.02.02.01.61.82.01.61.9
K content in liver1.51.52.11.31.11.11.51.21.01.31.4
Mg content in liver4.85.05.92.32.12.12.32.12.22.22.4
Mn content in liver3.54.04.51.91.91.92.12.12.02.02.0
Na content in liver0.70.81.00.80.90.81.00.90.81.01.0
Rb content in liver0.20.30.60.70.50.60.50.50.50.50.6
Se content in liver0.10.10.3-0.0-0.0-0.0-0.5-0.20.0-0.4-0.2
Sr content in liver0.60.60.70.70.80.70.80.80.80.60.9
Zn content in liver0.60.61.11.00.90.90.40.60.70.70.9