Unc80

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000028362	0.18	0.07	0.0e+00	0.12	0.13	0.14	0.13	1.1e-13	4.9e-14	9.5e-15	6.5e-14
2	BLA	intron excision ratio	chr9:68163137:68165373	0.09	0.04	1.2e-03	0.05	0.01	0.01	0.03	1.2e-03	1.3e-01	1.2e-01	1.6e-02
3	Brain	gene expression	ENSRNOG00000028362	0.05	0.03	6.9e-04	0.04	0.03	0.02	0.03	8.7e-05	4.9e-04	5.2e-03	4.2e-04
4	Eye	intron excision ratio	chr9:68017045:68024741	0.34	0.16	7.7e-03	0.12	0.18	0.19	0.13	5.9e-03	9.1e-04	6.3e-04	4.8e-03
5	Liver	gene expression	ENSRNOG00000028362	0.16	0.06	7.7e-15	0.06	0.07	0.06	0.06	5.6e-07	1.0e-08	1.3e-07	1.3e-07
6	PL	gene expression	ENSRNOG00000028362	0.06	0.05	4.4e-03	0.02	0.02	0.02	0.02	2.0e-02	8.1e-03	5.4e-03	2.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
BMI with tail	2.5	8.0	20.0	4.3	-4.5	0.6	-2.8	-1.0	0.8
BMI without tail	0.9	1.9	5.1	1.7	-2.3	0.2	-1.7	-0.5	-0.7
Body weight	0.2	0.8	3.0	-0.2	-0.6	1.7	-1.0	0.6	0.4
Epididymis fat weight	1.5	3.6	11.3	-0.9	-0.4	3.4	-1.6	2.4	0.7
Glucose	0.4	0.6	1.3	0.7	-1.0	1.1	-0.9	0.4	-0.1
Heart weight	0.3	0.4	0.9	-0.1	0.7	-0.1	1.0	0.5	-0.8
Left kidney weight	0.1	0.2	0.5	-0.1	-0.2	0.4	-0.6	0.1	0.7
Right kidney weight	0.4	1.1	1.9	-1.1	0.2	1.4	-1.3	1.3	0.3
Tail length	3.3	9.8	26.3	-5.1	3.9	1.6	0.3	2.6	-2.8
Length with tail	2.9	10.5	29.8	-5.5	4.7	1.9	1.5	2.3	-0.6
Length without tail	1.0	2.3	3.3	-1.7	1.6	1.8	0.5	1.3	1.7
Liver weight, left	0.8	1.2	2.9	-1.7	1.6	-0.3	1.0	0.3	-0.7
Liver weight, right	0.4	0.6	1.7	-0.9	1.3	-0.3	0.9	0.2	0.5
Parametrial fat weight	1.1	2.2	4.6	-2.1	1.0	1.2	-1.6	1.7	-0.9
Retroperitoneal fat weight	0.4	1.4	2.9	0.5	-1.6	1.2	-1.1	0.0	1.7
Intraocular pressure	0.8	1.2	2.4	1.6	-1.1	-1.0	-1.2	-1.0	-0.4
Extensor digitorum longus weight	1.4	5.5	12.7	2.4	-3.0	2.1	-3.6	1.0	-0.8
Soleus weight	0.1	0.3	0.8	0.1	-0.4	-0.5	-0.9	-0.5	-0.7
Tibialis anterior weight	0.2	0.7	1.9	1.2	-1.4	0.2	-0.6	-0.4	-0.3
Tibia length	1.0	2.8	7.0	-2.7	2.2	1.2	0.2	1.7	-0.8
Number of licking bursts	0.2	0.3	0.5	0.3	-0.6	0.7	-0.6	0.4	0.5
Food consumed during 24 hour testing period	1.4	1.6	3.9	-0.7	0.9	-2.0	1.2	-1.5	1.0
Times rat made contact with spout	0.6	0.7	1.6	-1.0	1.2	-1.2	0.4	-0.2	0.3
Mean time between licks in bursts	0.3	0.5	1.0	0.8	-0.7	0.4	-0.7	0.1	1.0
Mean num. licks in bursts	0.4	0.5	1.1	-0.7	1.0	-1.0	0.4	-0.3	-0.5
Std. dev. time between licks in bursts	1.8	2.1	4.6	1.8	-2.1	0.8	-1.9	0.1	-0.8
Water consumed over 24 hours	0.1	0.2	0.5	0.4	-0.3	-0.7	-0.4	-0.4	0.1
Indifference point 0 sec	1.0	1.6	4.1	0.8	-0.7	2.0	-1.3	1.5	-0.6
Indifference point AUC	0.3	0.4	1.6	-0.4	0.0	-0.2	-0.6	-0.0	-1.2
Indifference point function ln k	1.5	2.1	7.4	1.6	-1.1	-0.4	0.8	-0.9	2.7
Indifference point function log k	1.5	2.1	7.4	1.6	-1.1	-0.4	0.8	-0.9	2.7
Delay discounting total patch changes 0 sec	0.7	1.1	2.9	0.9	-0.6	1.7	-1.0	1.2	-0.5
Delay discounting total patch changes 12 sec	0.2	0.3	1.3	0.0	-0.1	0.2	-0.5	0.2	-1.1
Delay discounting total patch changes 18 sec	1.0	1.4	3.9	0.6	-0.7	0.8	-2.0	0.8	-1.4
Delay discounting total patch changes 24 sec	0.3	0.3	1.6	0.2	-0.1	0.4	0.0	0.3	-1.3
Delay discounting total patch changes 6 sec	0.9	1.4	2.1	0.9	-1.5	1.5	-1.4	0.6	-1.1
Delay discounting time to switch 0 sec	0.2	0.4	0.7	-0.6	0.7	-0.8	0.3	-0.5	-0.6
Delay discounting water rate 0 sec	0.4	0.6	1.5	0.4	-0.7	1.2	-1.0	0.8	-0.4
Delay discounting water rate 12 sec	0.4	0.6	1.2	1.1	-0.8	-0.8	0.8	-0.8	0.0
Delay discounting water rate 18 sec	1.0	1.3	4.5	-0.4	0.8	-0.8	2.1	-0.5	1.3
Delay discounting water rate 24 sec	0.0	0.0	0.0	-0.2	0.2	-0.0	-0.1	0.2	-0.2
Delay discounting water rate 6 sec	0.9	1.3	3.3	1.8	-1.8	0.3	-0.5	-0.1	-0.9
Locomotor activity	0.4	0.7	3.4	0.6	-0.6	0.1	-0.0	0.0	1.8
Locomotor testing distance	0.1	0.1	0.4	0.2	-0.2	0.2	-0.1	0.2	0.7
Locomotor testing rearing	0.1	0.2	1.1	0.1	0.1	0.2	0.4	0.1	1.0
Light reinforcement 1	0.9	1.7	2.7	1.6	-1.6	-1.1	-0.8	-1.5	0.8
Light reinforcement 2	1.0	1.3	2.9	-0.6	0.7	-1.4	1.7	-1.1	0.8
Reaction time number correct	0.3	0.5	1.8	1.4	-0.7	-0.5	0.3	-0.5	-0.0
Reaction time mean minus median	0.2	0.3	0.8	-0.4	0.3	-0.9	-0.7	-0.5	-0.2
Reaction time mean minus median AUC	0.3	0.4	1.3	-0.4	0.6	-1.1	0.2	-0.7	0.3
Reaction time num false alarms	1.4	2.0	4.9	1.8	-2.2	0.5	-1.7	-0.4	0.7
Reaction time num false alarms AUC	1.2	1.7	3.8	1.5	-1.9	0.8	-2.0	-0.1	0.3
Reaction time trials correct on left	0.3	0.5	1.8	1.4	-0.7	-0.5	0.3	-0.5	-0.0
Reaction time trials on left	0.3	0.4	1.7	1.3	-0.7	-0.5	0.3	-0.5	0.0
Reaction time mean	1.7	2.3	7.0	-2.3	2.6	-0.2	0.8	0.9	0.2
Reaction time mean AUC	1.6	2.1	5.7	-2.3	2.4	0.1	0.6	1.1	-0.0
Median of all reaction times	2.6	3.5	9.6	-2.7	3.1	0.5	1.1	1.6	0.2
Reaction time omissions	0.3	0.3	0.9	-1.0	0.1	0.5	-0.8	0.4	0.4
Reaction time false alarm rate	0.7	1.1	3.3	0.5	-1.3	0.9	-1.8	0.2	0.2
Reaction time premature initiation rate	0.6	0.9	1.9	-0.1	1.0	-0.8	1.3	-0.2	1.4
Reaction time premature initiations	0.7	1.0	1.7	0.8	0.5	-1.3	1.3	-0.6	1.2
Std. dev. reaction times	0.6	0.8	2.4	-1.6	1.3	-0.8	0.1	-0.2	0.2
Reaction time trials completed	0.3	0.4	1.7	1.3	-0.7	-0.5	0.3	-0.5	0.0
Reaction time trials AUC	0.3	0.4	1.4	1.2	-0.5	-0.5	0.4	-0.5	-0.0
Social response proportion	0.3	0.4	2.0	-0.1	-0.0	0.4	-0.1	0.2	1.4
Social responses	0.3	0.4	1.2	-0.6	0.6	0.1	0.2	0.3	1.1
Social time	0.6	0.8	1.8	-0.1	1.0	-0.3	1.3	-0.4	1.4
Conditioned locomotion	0.3	0.4	0.5	-0.5	0.6	0.7	-0.3	0.7	-0.6
Cocaine response after cond. corrected	0.4	0.4	0.9	-0.8	0.9	-0.2	0.0	0.5	-0.9
Cocaine response after cond. not corrected	0.8	0.8	2.1	-1.4	1.3	0.2	0.8	0.7	-0.3
Cocaine response before conditioning	0.9	1.1	2.5	-0.9	0.4	1.2	1.2	0.7	1.6
Saline control response	0.7	0.9	1.5	1.2	-1.2	0.8	-0.6	0.3	-1.2
Condit. Reinf. active minus inactive responses	3.4	4.2	9.6	-2.9	3.1	0.7	1.8	1.9	-0.1
Condit. Reinf. active-inactive response ratio	3.1	3.3	7.6	-2.7	2.7	-0.0	1.9	1.0	0.0
Condit. Reinf. active responses	2.3	3.3	6.5	-2.4	2.6	0.9	1.8	1.9	-0.2
Condit. Reinf. inactive responses	0.3	0.3	0.8	-0.5	0.5	0.8	0.5	0.9	0.2
Condit. Reinf. lever presses	0.6	0.8	3.6	-0.6	1.0	-0.3	1.9	0.2	-0.0
Condit. Reinf. lever reinforcers received	2.5	3.5	7.2	-2.5	2.7	0.8	1.9	1.7	-0.0
Pavlov. Cond. lever latency	0.9	1.2	4.1	0.7	-1.3	1.0	-2.0	0.1	-0.2
Pavlov. Cond. magazine entry latency	1.2	1.4	3.0	0.0	0.6	-1.7	1.7	-1.2	-0.6
Pavlov. Cond. change in total contacts	0.7	1.0	3.1	-0.8	1.4	-0.6	1.8	0.3	-0.4
Pavlov. Cond. index score	1.4	1.8	5.5	-0.7	1.5	-1.5	2.4	-0.5	-0.2
Pavlov. Cond. latency score	1.3	1.6	5.0	-0.7	1.5	-1.4	2.2	-0.5	-0.2
Pavlov. Cond. lever contacts	1.3	1.8	5.1	-1.2	1.8	-1.0	2.2	0.0	0.1
Pavlov. Cond. magazine entry number	1.2	1.5	4.5	0.2	-0.9	1.7	-2.1	1.0	0.0
Pavlov. Cond. intertrial magazine entries	2.1	2.8	6.9	0.2	-1.4	2.6	-2.2	1.5	-0.8
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.9	6.0	-0.5	1.4	-1.7	2.4	-0.7	-0.2
Pavlov. Cond. response bias	1.3	1.9	5.5	-0.9	1.7	-1.4	2.3	-0.3	0.1
Conditioned reinforcement - actives	0.3	0.3	0.9	0.5	-0.6	0.4	-1.0	0.2	-0.5
Conditioned reinforcement - inactives	0.7	0.8	2.3	-1.0	1.5	0.5	0.0	0.9	-0.9
Conditioned locomotion	3.1	3.7	9.9	3.2	-2.6	-0.5	-0.8	-1.4	1.6
Intermittent access intake day 1-15 change	0.4	0.4	0.8	0.8	0.1	-0.4	0.8	-0.9	0.2
Intermittent access intake escalation	0.9	0.9	1.9	0.9	0.2	-1.0	1.3	-1.4	0.0
Intermittent access intake escalation 2	1.5	1.5	3.6	0.9	0.1	-1.3	1.9	-1.5	0.5
Intermitt. access day 1 inactive lever presses	0.4	0.5	0.8	-0.8	0.5	0.2	-0.9	0.8	-0.6
Intermitt. access day 15 inactive lever presses	1.3	1.4	2.6	-0.8	1.4	-0.7	1.6	-1.1	1.2
Intermitt. access escalation Index	1.5	1.4	2.4	1.2	-1.1	-0.9	1.0	-1.6	1.2
Intermittent access day 1 total infusions	0.2	0.3	0.6	-0.6	0.1	0.5	0.3	0.5	-0.8
Intermittent access day 15 total infusions	0.3	0.3	0.8	0.7	-0.5	0.2	0.9	-0.5	0.0
Intermittent access terminal intake (last 3 days)	0.7	0.8	1.9	1.0	-0.7	-0.5	1.4	-1.1	0.1
Intermittent access total infusions	0.2	0.2	0.9	-0.0	-0.2	0.3	1.0	-0.2	-0.3
Intermittent access day 1 locomotion	0.3	0.3	0.9	-0.2	0.1	0.7	-0.0	1.0	-0.5
Intermittent access day 15 total locomotion	0.3	0.3	0.6	0.7	-0.7	-0.4	0.8	-0.4	0.2
Intermittent access total locomotion	0.3	0.4	1.5	1.2	-0.7	-0.0	0.1	-0.2	0.4
Intermittent access standard deviation	1.5	1.6	4.5	0.4	1.1	-1.2	2.1	-1.1	1.1
Cocaine induced anxiety	1.0	1.1	2.9	0.0	0.1	-1.3	0.8	-1.1	1.7
Post-drug Anxiety	1.0	1.0	3.6	0.6	-0.9	-0.6	-0.2	-1.0	1.9
Baseline Anxiety	0.7	0.7	1.4	0.3	-0.5	1.1	-1.2	0.7	-1.0
Lifetime Intake	0.1	0.2	0.4	0.1	-0.6	0.5	0.5	-0.1	-0.4
Incentive Sensitization - Responses	0.4	0.4	1.9	-0.1	0.1	0.4	0.7	0.3	-1.4
Incentive Sensitization - Breakpoint	0.5	0.5	2.4	-0.2	0.0	0.4	0.6	0.4	-1.5
Progressive ratio test 1 active lever presses	0.2	0.2	0.6	0.4	-0.5	0.8	0.2	0.3	0.1
Progressive ratio test 1 breakpoint	0.2	0.2	0.5	0.3	-0.4	0.7	0.6	0.2	0.2
Progressive ratio test 1 inactive lever presses	0.3	0.3	0.8	0.9	-0.7	0.0	-0.2	-0.6	0.4
Progressive ratio test 2 active lever presses	0.4	0.4	1.6	0.1	-0.3	0.8	0.5	0.3	-1.3
Progressive ratio test 2 breakpoint	0.3	0.3	0.7	0.1	-0.1	0.8	0.6	0.4	-0.7
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.3	-0.0	-0.0	0.2	0.3	-0.1	-0.5
Total sessions with >9 infusions	0.4	0.4	1.0	-0.3	0.0	0.8	0.1	0.9	-1.0
Short access day 1 total inactive lever presses	0.2	0.2	0.3	0.3	-0.5	0.2	0.6	-0.4	0.6
Short access day 10 total inactive lever presses	1.0	1.1	2.6	-1.0	1.3	-0.9	1.0	-0.3	1.6
Short access day 1 total infusions	0.7	0.8	1.2	0.9	-1.0	-0.0	1.1	-0.7	1.0
Short access day 10 total infusions	0.3	0.3	1.6	-0.3	0.0	0.0	1.2	-0.3	-0.2
Short access total infusions	0.3	0.3	1.0	0.7	-1.0	0.4	0.3	-0.2	-0.1
Short access day 1 locomotion	0.8	0.8	2.4	-0.6	0.7	1.2	0.2	1.6	0.0
Short access day 10 total locomotion	0.6	0.6	1.2	-0.0	0.6	-1.1	1.1	-0.2	1.0
Short access total locomotion	0.1	0.1	0.2	0.4	-0.3	0.1	0.4	0.4	0.4
Compulsive drug intake	0.3	0.3	0.6	-0.6	0.6	0.1	-0.6	0.8	-0.4
One hour access (0.3 mA shock)	0.3	0.3	1.0	-0.3	0.7	-0.6	1.0	-0.1	-0.2
One hour access (shock baseline)	0.2	0.3	1.2	-0.3	0.1	-0.3	1.1	-0.5	0.1
Number of responses in last shaping day	2.3	2.3	5.1	-1.6	1.0	2.2	-0.3	2.3	-0.4
Context. condit. distance diff. score	0.9	1.0	3.0	0.1	-0.8	-0.7	0.6	-1.3	1.7
Locomotion velocity, session 1	1.6	1.7	6.1	-0.8	1.1	0.0	-1.0	1.0	-2.5
Locomotion distance, session 1	0.4	0.5	2.4	0.3	-0.3	-0.4	-0.7	-0.2	-1.5
Locomotion velocity, session 2	2.2	2.6	5.2	-0.2	-0.4	2.3	-1.9	2.0	-1.7
Locomotion distance, session 2	1.1	1.5	4.5	0.7	-0.8	0.2	-2.1	0.3	-1.8
Locomotion velocity, session 3	2.0	2.4	4.5	0.8	-0.5	-2.0	1.2	-2.1	1.8
Locomotion distance, session 3	0.8	0.9	2.3	-1.5	1.5	-0.2	0.7	0.6	-0.0
Stereotopy head waving bouts, day 3	2.4	2.9	6.7	2.6	-1.8	-1.8	0.2	-2.0	0.7
Stereotopy head waving duration, day 3	3.1	3.8	7.0	2.5	-2.1	-2.1	0.1	-2.6	0.9
Locomotion velocity, session 7	0.5	0.5	1.2	-0.5	-0.2	1.1	-0.8	1.0	-0.3
Locomotion distance, session 7	2.5	3.2	5.9	-1.2	0.3	2.0	-2.0	2.4	-1.9
Stereotopy head waving bouts, day 7	0.1	0.2	0.3	0.3	-0.5	0.1	0.5	-0.3	0.6
Stereotopy head waving duration, day 7	1.9	2.3	4.8	1.2	-1.4	-0.9	0.8	-2.1	2.2
Locomotion velocity, session 8	0.1	0.2	0.5	0.7	-0.6	0.0	-0.4	-0.0	-0.1
Locomotion distance, session 8	0.1	0.2	0.4	0.2	-0.7	0.0	-0.5	-0.2	0.3
Degree of sensitization distance	1.5	1.5	3.6	0.7	-1.2	1.3	-1.9	0.8	-1.2
Degree of sensitization stereotypy	0.2	0.2	0.6	0.2	-0.6	0.8	-0.1	0.1	0.6
Condit. Reinf. active minus inactive responses	0.8	0.9	1.9	-0.9	1.0	0.5	0.8	1.0	-1.4
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.9	-0.1	0.3	-0.3	0.5	0.1	-0.9
Condit. Reinf. active responses	1.3	1.5	2.2	-1.3	1.3	1.1	0.9	1.5	-1.3
Condit. Reinf. inactive responses	0.8	1.0	1.6	-1.0	1.0	1.1	0.2	1.3	-0.9
Incentive salience index mean	1.0	1.2	2.0	-1.0	1.0	1.0	0.9	1.4	-1.2
Condit. Reinf. lever presses	0.5	0.6	1.2	-0.7	0.8	1.0	0.7	1.1	-0.3
Time in familiar zone, hab. session 1	2.9	2.8	4.9	2.1	-1.6	-1.4	1.1	-2.2	1.3
Time in novel zone, hab. session 1	3.2	3.1	7.9	-2.8	2.8	0.3	0.4	1.6	-0.7
Total zone transitions, hab. session 1	1.4	1.9	4.0	-1.2	0.7	1.6	-0.5	1.7	-2.0
Total locomotion distance, hab. session 1	1.2	1.7	3.4	-1.4	1.3	0.8	0.7	1.4	-1.9
Locomotion velocity, hab. session 1	1.3	1.8	3.0	-1.4	1.1	1.3	0.2	1.7	-1.7
Time in familiar zone, hab. session 2	0.9	1.0	2.9	0.4	-0.7	-1.4	0.6	-1.7	0.0
Time in novel zone, hab. session 2	0.6	0.6	1.6	-0.2	0.5	1.0	-0.6	1.3	0.0
Total zone transitions, hab. session 2	0.1	0.1	0.2	0.1	-0.0	-0.3	-0.2	-0.3	-0.4
Total locomotion distance, hab. session 2	0.1	0.1	0.7	0.1	-0.0	-0.0	-0.3	0.1	-0.8
Locomotion velocity, hab. session 2	0.1	0.1	0.7	0.1	-0.0	-0.0	-0.3	0.1	-0.8
Novel to familiar place preference ratio	1.0	1.0	1.7	-1.3	1.2	0.7	-0.3	0.7	-1.3
Novelty place preference	0.8	0.8	1.6	-1.3	1.3	0.4	-0.1	0.5	-1.0
Time in novel zone, NPP test	0.8	0.9	2.1	-1.4	1.4	0.2	0.2	0.3	-1.0
Total zone transitions, NPP test	0.1	0.2	1.0	-0.1	-0.0	-0.0	-0.4	0.0	-1.0
Total locomotion distance, NPP test	0.7	0.9	4.6	-0.3	0.4	0.2	-0.5	0.6	-2.1
Locomotion velocity, NPP test	0.7	1.0	5.0	0.1	0.1	0.3	-0.7	0.6	-2.2
Pavlov. Cond. lever latency	2.1	2.7	8.5	0.6	-0.0	-2.9	0.8	-2.5	0.7
Pavlov. Cond. magazine entry latency	0.7	0.9	1.4	-1.2	0.8	1.2	0.8	1.1	-0.7
Pavlov. Cond. change in total contacts	1.5	1.6	5.1	-0.3	-0.3	2.3	-0.6	1.7	-1.1
Pavlov. Cond. index score	1.2	1.6	4.2	-1.1	0.6	2.1	0.3	1.8	-0.7
Pavlov. Cond. latency score	1.1	1.5	4.0	-1.0	0.5	2.0	0.2	1.7	-0.6
Pavlov. Cond. lever contacts	1.2	1.4	4.2	-0.3	0.1	2.1	-0.3	1.8	-0.8
Pavlov. Cond. magazine entry number	1.3	1.7	2.8	1.1	-0.7	-1.7	-0.1	-1.6	1.6
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	0.4	-0.2	0.1	0.1	0.4	0.3
Pavlov. Cond. lever-magazine prob. diff.	1.0	1.2	3.1	-0.8	0.6	1.8	0.3	1.6	-0.6
Pavlov. Cond. response bias	1.6	1.9	3.7	-1.0	0.8	1.9	0.1	1.9	-1.5
Bone: apparent density	0.2	0.3	1.3	-0.7	0.2	0.0	1.1	-0.2	-0.3
Bone surface	0.4	0.7	1.5	-0.8	0.3	1.2	0.6	1.1	-0.5
Bone volume	0.6	0.9	2.3	-1.5	1.0	0.4	1.4	0.4	-0.3
Bone: connectivity density	0.4	0.7	2.0	0.5	-1.2	1.4	-0.1	0.7	-0.3
Bone: cortical apparent density	2.3	2.9	5.3	2.3	-2.2	1.2	-2.3	0.9	-0.1
Bone: cortical area	1.2	1.8	4.6	-1.1	0.9	1.6	-0.8	2.2	-1.1
Bone: cortical porosity	3.9	4.2	10.0	-3.2	3.1	-0.4	2.2	0.4	0.3
Bone: cortical porosity	4.1	4.4	11.0	-3.3	3.3	-0.4	2.0	0.6	0.1
Bone: cortical thickness	1.7	2.7	6.2	-0.5	0.3	1.9	-1.6	2.5	-1.9
Bone: cortical thickness	0.5	0.6	1.3	-0.9	1.1	-0.0	0.9	0.7	-0.4
Bone: cortical tissue density	2.4	3.1	5.6	2.4	-2.4	1.2	-2.3	0.8	-0.1
Bone: elastic displacement	0.3	0.4	0.9	0.9	-0.4	-0.4	0.6	-0.1	0.9
Bone: elastic work	0.3	0.4	1.1	-0.4	0.5	0.6	0.6	1.0	0.3
Bone: endosteal estimation	0.8	1.8	3.5	-1.9	1.8	-0.5	1.9	-0.2	0.6
Bone: endosteal perimeter	0.6	1.2	2.7	-1.0	1.2	-0.7	1.7	-0.6	1.0
Bone: final force	0.7	1.1	2.5	-1.6	1.4	0.0	1.4	0.4	0.2
Bone: final moment	0.5	0.8	1.8	-1.3	1.1	0.0	1.3	0.3	0.0
Bone: marrow area	0.8	1.6	3.4	-1.9	1.8	-0.3	1.7	-0.0	0.4
Bone: maximum diameter	0.6	1.1	2.3	-1.3	1.5	0.7	0.3	1.3	-0.4
Bone: maximum force	0.4	0.7	1.5	-1.1	0.9	-0.5	1.2	-0.3	-0.4
Bone: maximum moment	0.3	0.5	1.3	-0.8	0.6	-0.6	1.1	-0.5	-0.5
Bone: minimum diameter	0.9	1.7	4.3	-2.1	1.7	0.8	0.7	1.3	0.1
Bone: periosteal estimation	0.9	1.9	4.5	-2.1	1.9	0.8	0.7	1.4	-0.5
Bone: periosteal perimeter	0.6	1.0	2.6	-1.4	1.6	-0.3	1.1	0.3	0.2
Bone: post-yield work	0.7	1.0	2.6	0.1	-0.1	-1.6	0.7	-1.6	-0.5
Bone: stiffness	0.5	0.8	1.9	-0.9	0.6	-0.8	1.4	-0.9	0.3
Bone: tissue strength	0.1	0.1	0.3	0.1	-0.5	0.1	-0.4	-0.3	-0.0
Bone: trabecular number	0.2	0.3	0.7	0.2	-0.8	0.2	0.9	-0.5	0.0
Bone: trabecular spacing	0.9	1.2	2.9	-0.9	1.1	1.0	-1.2	1.7	0.2
Bone: trabecular thickness	0.7	0.8	1.7	-0.7	0.4	-1.3	1.0	-1.2	-0.2
Bone: trabecular tissue density	0.3	0.4	1.0	-0.2	1.0	-0.5	-0.5	0.7	-0.5
Breakpoint value in progressive ratio session	1.2	1.3	1.7	-0.4	1.3	-1.3	1.3	-1.0	1.2
Distance traveled before self-admin	1.1	1.2	3.4	-0.6	0.7	-0.3	1.7	-0.6	1.8
Distance traveled after self-admin	0.7	0.8	2.6	0.1	-1.1	0.9	0.1	0.2	1.6
Delta time in closed arm before/after self-admin	0.9	0.8	2.8	0.3	-0.5	1.7	-0.5	0.9	-1.0
Delta time in open arm before/after self-admin	3.5	3.3	5.2	-0.4	2.0	-2.1	2.3	-1.7	1.9
Diff in mean of infusions in LGA sessions	1.9	2.1	5.2	2.3	-1.2	-1.2	0.8	-1.8	0.9
Extinction: sum of active levers before priming	2.6	2.7	9.9	0.9	-0.4	-1.1	1.3	-1.6	3.2
Active lever presses in extinction session 6	0.1	0.1	0.2	-0.3	0.3	0.2	-0.0	0.4	-0.4
Delta distance traveled before/after self-admin	1.0	1.0	3.2	0.9	-1.8	0.8	-0.7	0.2	1.0
Delta ambulatory time before/after self-admin	0.8	0.9	2.1	0.3	-1.4	1.1	-0.9	0.8	0.6
Time in closed arm before self-admin	0.8	0.9	2.2	-1.5	0.8	-1.0	1.3	-0.0	-0.0
Time in closed arm after self-admin	1.5	1.6	3.9	-1.3	0.3	1.2	-0.3	1.6	-2.0
Time in open arm before self-admin	2.6	2.7	4.4	1.8	-2.0	1.8	-2.1	0.9	-0.8
Time in open arm after self-admin	0.7	0.7	1.1	0.2	0.9	-1.0	0.8	-1.1	1.0
Sum of active levers in priming session hrs 5-6	0.9	0.9	3.3	-0.6	0.4	1.1	-0.1	0.7	1.8
Time to tail flick, vehicle, before self-admin	0.3	0.3	1.2	-0.3	-0.0	-0.2	-0.6	0.5	-1.1
Time to tail flick, vehicle, after self-admin	0.5	0.5	1.6	-0.9	0.6	-0.5	-0.2	0.2	-1.3
Time to tail flick, test, before self-admin	1.2	1.2	2.4	-1.3	0.7	0.5	-0.9	1.2	-1.6
Time to tail flick, test, after self-admin	2.4	2.4	6.8	2.6	-1.9	-0.9	-0.4	-1.6	0.8
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	1.7	0.4	-0.2	-1.0	0.5	-1.3	0.6
Delta time to tail flick, test, before/after SA	4.1	3.7	8.9	3.0	-1.8	-1.1	0.8	-2.0	2.0
Ambulatory time before self-admin	0.9	0.9	3.1	-0.0	0.2	-0.4	1.2	-0.8	1.8
Ambulatory time after self-admin	1.7	1.9	5.4	0.7	-1.9	1.3	-0.4	0.3	2.3
Total heroin consumption	1.6	1.9	4.8	-0.7	1.7	-1.2	0.9	-0.9	2.2
Area under the delay curve	0.2	0.2	0.6	0.7	-0.3	0.2	0.1	-0.2	-0.8
Delay disc. indifference point, 0s delay	0.6	0.6	1.2	1.1	-1.1	-0.3	-0.6	-0.7	-0.6
Delay disc. indifference point, 16s delay	0.5	0.5	2.1	0.6	0.1	0.2	1.4	-0.4	0.5
Delay disc. indifference point, 2s delay	1.2	1.3	2.5	1.6	-1.3	-0.8	0.5	-1.4	0.8
Delay disc. indifference point, 24s delay	0.5	0.5	1.7	0.7	-0.6	1.3	-0.5	0.7	-0.1
Delay disc. indifference point, 4s delay	0.9	1.0	2.4	0.9	-1.2	-0.1	-1.0	-0.5	-1.6
Delay disc. indifference point, 8s delay	0.6	0.6	1.9	0.0	0.1	1.0	-0.3	0.7	-1.4
Delay discount exponential model param	0.2	0.2	0.6	-0.8	0.3	-0.2	-0.1	0.3	0.7
Delay discount hyperbolic model param	0.3	0.3	0.8	-0.9	0.5	-0.1	0.1	0.3	0.9
Fecal boli incidents, locomotor time 1	1.0	1.1	2.1	-1.5	1.4	-0.1	1.0	-0.0	1.3
Change in fecal boli incidents, locomotor task	0.2	0.2	1.1	0.4	0.2	-0.2	0.1	0.1	-1.0
Time >=10cm from walls, locomotor time 1	1.1	1.1	2.2	-1.1	1.5	-0.2	0.4	1.2	-1.2
Bouts of movement, locomotor time 1	0.5	0.6	1.0	-0.8	1.0	0.1	-0.6	1.0	-0.8
Total resting periods, locomotor time 1	0.9	1.0	1.7	-0.8	0.8	0.3	-1.1	1.3	-1.3
Rest time, locomotor task time 1	0.3	0.4	0.6	-0.6	0.8	0.1	-0.5	0.7	0.7
Distance moved, locomotor task time 1	0.5	0.5	1.2	-0.0	-0.6	1.1	-0.7	0.8	-0.6
Vertical activity count, locomotor time 1	0.2	0.2	0.8	0.3	-0.9	0.3	0.3	-0.2	-0.4
Time >=10cm from walls, locomotor time 2	0.4	0.4	1.3	-0.3	0.9	-1.2	-0.0	-0.4	-0.1
Bouts of movement, locomotor time 2	0.7	0.8	1.8	0.9	-0.5	1.1	-1.3	0.9	0.1
Total resting periods, locomotor time 2	0.5	0.6	1.3	0.5	-0.1	0.9	-1.1	0.9	0.2
Rest time, locomotor task time 2	1.0	1.1	1.9	-1.1	1.0	0.7	-0.7	1.3	-1.4
Distance moved, locomotor task time 2	0.3	0.4	0.7	0.6	-0.7	0.3	-0.9	0.1	0.7
Vertical activity count, locomotor time 2	2.2	2.4	4.8	1.8	-1.9	-0.7	-0.3	-1.5	2.2
Weight adjusted by age	0.3	0.3	0.6	0.8	-0.5	0.7	0.1	0.3	0.7
Seeking ratio, delayed vs. immediate footshock	0.6	0.7	2.4	-0.5	0.8	-0.7	1.6	-0.8	0.3
Locomotion in novel chamber	0.9	1.1	2.2	1.5	-0.7	-0.8	0.6	-1.3	1.0
Locomotion in novel chamber post-restriction	0.5	0.5	1.3	0.3	-0.2	1.0	-0.9	1.1	-0.1
Progressive ratio	0.9	1.1	3.2	-0.4	0.3	0.7	-0.9	1.3	-1.8
Food seeking constrained by brief footshock	1.3	1.5	4.1	1.9	-2.0	0.2	-0.4	-0.9	0.7
Seeking ratio, punishment vs. effort	1.4	1.8	3.4	1.2	-1.3	-0.6	0.9	-1.7	1.9
Run reversals in cocaine runway, females	1.8	1.8	6.5	0.1	-0.3	0.9	-1.7	0.8	-2.5
Run reversals in cocaine runway, males	0.2	0.1	0.5	-0.2	0.4	0.3	0.2	0.2	0.7
Latency to leave start box in cocaine runway	2.0	2.2	4.5	1.4	-1.3	1.6	-2.1	1.2	-0.9
Latency to leave start box in cocaine runway, F	1.3	1.5	2.9	1.3	-1.5	1.2	-1.7	0.7	-0.3
Latency to leave start box in cocaine runway, M	0.3	0.3	1.3	0.2	0.3	0.5	-0.1	0.6	-1.2
Cd content in liver	1.2	1.4	3.4	0.6	-0.2	-1.6	1.3	-1.9	0.3
Co content in liver	0.2	0.2	0.9	0.4	-0.3	-0.0	0.3	-0.3	0.9
Cu content in liver	1.0	1.3	4.3	-0.4	0.1	2.1	-0.6	1.6	0.3
Fe content in liver	0.3	0.4	0.7	-0.9	0.6	-0.4	0.7	-0.2	0.7
K content in liver	0.5	0.5	0.9	0.6	-0.9	1.0	-0.8	0.5	-0.3
Mg content in liver	0.3	0.3	1.1	0.8	-1.0	0.5	0.0	-0.1	0.0
Mn content in liver	1.1	1.2	3.4	1.9	-1.6	-0.2	-0.9	-0.6	0.6
Na content in liver	0.3	0.3	0.7	-0.8	0.5	0.5	0.6	0.5	-0.3
Rb content in liver	0.5	0.6	1.8	0.4	-0.1	1.3	-0.1	1.3	0.1
Se content in liver	0.2	0.2	0.6	0.5	-0.6	0.2	-0.3	-0.3	0.8
Sr content in liver	0.9	0.8	1.5	-0.3	0.5	0.7	-1.2	1.1	-1.2
Zn content in liver	0.3	0.4	0.7	0.6	-0.7	0.7	-0.8	0.2	0.4