Hub : Genes

Nfe2l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000008830 0.56 0.12 0.0e+00 0.55 0.61 0.61 0.61 6.9e-35 1.5e-40 1.6e-40 5.5e-41
2 Brain gene expression ENSRNOG00000008830 0.6 0.1 0.0e+00 0.7 0.7 0.71 0.71 1.3e-89 2.8e-91 3.4e-92 3.1e-92
3 Brain mRNA stability ENSRNOG00000008830 0.03 0.03 7.0e-03 0.02 0.02 0.01 0.01 7.9e-03 9.1e-03 1.4e-02 1.6e-02
4 Eye gene expression ENSRNOG00000008830 0.75 0.15 7.7e-08 0.1 0.09 0.05 0.11 1.4e-02 1.6e-02 5.7e-02 9.6e-03
5 IL gene expression ENSRNOG00000008830 0.73 0.11 0.0e+00 0.42 0.43 0.45 0.28 3.1e-11 1.2e-11 4.0e-12 2.1e-07
6 LHb gene expression ENSRNOG00000008830 0.56 0.16 6.1e-13 0.27 0.37 0.31 0.32 3.4e-07 1.2e-09 3.6e-08 2.3e-08
7 Liver alternative TSS ENSRNOT00000067542 0.15 0.11 3.3e-03 0.01 0.01 0.01 0.01 1.9e-02 1.6e-02 5.3e-02 2.2e-02
8 Liver alternative TSS ENSRNOT00000111539 0.15 0.1 3.6e-03 0.01 0.01 0 0.01 1.9e-02 1.8e-02 1.0e-01 2.3e-02
9 NAcc alternative TSS ENSRNOT00000067542 0.18 0.12 5.0e-03 0.01 0.02 0.01 0.01 4.5e-02 7.6e-03 6.2e-02 5.0e-02
10 NAcc alternative TSS ENSRNOT00000111539 0.12 0.1 6.3e-03 0.02 0.02 0 0.01 1.6e-02 9.0e-03 2.8e-01 2.4e-02
11 NAcc gene expression ENSRNOG00000008830 0.17 0.09 1.9e-11 0.12 0.14 0.11 0.12 4.2e-09 2.9e-10 8.2e-09 1.9e-09
12 NAcc isoform ratio ENSRNOT00000067542 0.09 0.06 8.2e-05 0.05 0.05 0.05 0.05 7.7e-05 1.5e-04 1.9e-04 8.6e-05
13 OFC alternative TSS ENSRNOT00000067542 0.24 0.17 2.3e-03 0.07 0.09 0.1 0.1 1.1e-02 3.4e-03 2.0e-03 2.0e-03
14 OFC gene expression ENSRNOG00000008830 0.8 0.09 0.0e+00 0.37 0.5 0.4 0.4 1.1e-09 1.3e-13 1.4e-10 1.4e-10
15 PL gene expression ENSRNOG00000008830 0.5 0.07 0.0e+00 0.57 0.6 0.6 0.6 1.6e-52 1.7e-56 2.9e-56 1.5e-56

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail12.440.362.4-6.4-6.2-6.0-7.9-7.3-6.84.3-4.45.9-6.5-6.96.56.1-6.6-6.5
BMI without tail1.53.14.3-1.6-1.7-1.7-1.7-1.6-1.72.1-2.12.1-2.1-1.81.61.2-1.7-1.6
Body weight1.25.018.1-1.3-1.3-1.0-2.0-1.4-1.43.3-3.34.3-3.4-1.81.50.1-1.5-1.5
Epididymis fat weight0.10.20.9-0.10.20.2-0.3-0.2-0.10.5-0.51.0-0.7-0.20.1-0.2-0.1-0.1
Glucose0.81.33.6-0.9-0.8-0.5-1.3-1.0-1.01.3-1.31.9-1.6-1.10.90.4-1.0-0.9
Heart weight1.92.74.8-1.6-1.4-0.8-1.6-1.8-1.41.6-1.62.2-2.0-1.61.91.2-1.4-1.7
Left kidney weight0.51.47.10.20.10.7-0.10.20.22.1-2.12.7-1.8-0.10.0-1.30.10.1
Right kidney weight0.82.38.0-0.9-0.9-0.5-1.1-0.8-0.92.5-2.42.8-2.3-1.21.0-0.0-1.0-0.9
Tail length9.729.350.46.05.65.27.17.06.2-1.11.2-2.33.85.9-5.9-6.95.85.9
Length with tail5.821.342.55.25.05.15.75.85.3-0.20.4-0.52.24.9-5.0-6.55.05.0
Length without tail0.30.61.90.70.81.20.10.40.60.4-0.41.4-0.70.4-0.6-1.30.60.6
Liver weight, left0.71.22.71.01.21.61.21.11.2-0.70.7-0.70.91.2-1.0-1.01.21.0
Liver weight, right0.81.32.91.31.41.61.11.31.4-0.00.10.50.21.2-1.1-1.71.41.2
Parametrial fat weight0.00.10.9-0.1-0.1-1.00.20.1-0.10.3-0.3-0.30.10.00.10.2-0.1-0.1
Retroperitoneal fat weight0.72.36.4-1.2-0.9-0.6-0.7-0.8-1.02.5-2.52.5-2.1-1.21.40.5-1.1-1.3
Intraocular pressure1.21.73.41.51.40.91.91.81.5-0.20.2-0.70.91.5-1.4-1.61.41.4
Extensor digitorum longus weight0.31.36.3-0.4-0.5-0.0-1.4-0.8-0.71.3-1.32.5-1.9-1.00.5-0.2-0.7-0.5
Soleus weight1.13.34.7-1.8-1.7-1.2-2.2-2.0-1.91.6-1.62.1-2.1-2.01.81.5-1.8-1.8
Tibialis anterior weight0.20.82.11.11.01.40.81.10.9-0.30.3-0.10.40.8-1.1-1.20.91.0
Tibia length0.61.75.4-0.8-0.9-1.0-1.4-1.0-1.11.6-1.62.3-2.0-1.30.80.2-1.1-0.8
Number of licking bursts0.20.20.60.40.30.20.30.40.3-0.70.7-0.80.70.4-0.4-0.10.30.4
Food consumed during 24 hour testing period1.41.72.41.41.31.01.31.61.4-0.90.9-1.21.31.4-1.4-1.31.31.4
Times rat made contact with spout0.10.20.60.30.20.10.40.40.3-0.40.4-0.80.60.3-0.4-0.10.30.3
Mean time between licks in bursts0.10.20.8-0.3-0.3-0.1-0.9-0.6-0.50.1-0.10.6-0.6-0.50.30.2-0.4-0.2
Mean num. licks in bursts0.00.00.10.20.20.20.20.10.2-0.00.1-0.00.10.2-0.2-0.30.20.1
Std. dev. time between licks in bursts1.01.21.5-1.2-1.2-1.0-0.8-1.0-1.11.1-1.10.7-0.9-1.11.21.2-1.2-1.2
Water consumed over 24 hours0.30.40.80.60.50.30.10.40.5-0.90.9-0.80.70.5-0.7-0.30.50.6
Indifference point 0 sec0.91.42.2-1.2-1.4-1.2-0.9-0.9-1.21.5-1.51.0-1.1-1.21.21.0-1.2-1.2
Indifference point AUC0.20.20.60.30.50.50.50.50.5-0.60.6-0.80.70.5-0.3-0.20.50.4
Indifference point function ln k0.10.10.30.10.0-0.30.20.2-0.00.6-0.60.3-0.3-0.0-0.2-0.4-0.00.2
Indifference point function log k0.10.10.30.10.0-0.30.20.2-0.00.6-0.60.3-0.3-0.0-0.2-0.4-0.00.2
Delay discounting total patch changes 0 sec1.01.62.6-1.2-1.4-1.2-1.0-1.0-1.21.6-1.61.2-1.3-1.21.20.9-1.3-1.2
Delay discounting total patch changes 12 sec0.10.20.7-0.5-0.5-0.8-0.1-0.2-0.40.2-0.2-0.40.1-0.30.40.6-0.4-0.4
Delay discounting total patch changes 18 sec1.21.52.5-1.5-1.4-1.2-1.1-1.3-1.30.8-0.80.5-0.8-1.31.51.6-1.4-1.4
Delay discounting total patch changes 24 sec1.51.92.8-1.6-1.6-1.5-1.0-1.2-1.21.4-1.40.8-1.0-1.21.71.5-1.4-1.6
Delay discounting total patch changes 6 sec0.60.91.5-1.1-1.1-1.1-0.8-0.9-1.10.7-0.80.3-0.6-1.01.01.2-1.1-1.0
Delay discounting time to switch 0 sec0.10.10.3-0.3-0.4-0.50.0-0.1-0.30.1-0.1-0.30.1-0.20.30.5-0.3-0.3
Delay discounting water rate 0 sec1.01.63.9-1.0-1.1-0.9-1.3-1.1-1.01.6-1.62.0-1.7-1.21.10.5-1.1-1.1
Delay discounting water rate 12 sec0.10.21.00.40.40.4-0.4-0.00.20.1-0.11.0-0.60.0-0.4-0.70.20.3
Delay discounting water rate 18 sec0.30.31.00.70.70.60.20.40.7-0.30.30.40.10.6-0.7-1.00.70.6
Delay discounting water rate 24 sec0.71.01.7-0.9-0.9-1.0-1.3-1.1-1.00.9-0.91.3-1.2-1.00.90.7-1.0-1.0
Delay discounting water rate 6 sec0.00.00.20.10.10.2-0.0-0.10.2-0.40.4-0.20.20.10.00.00.2-0.1
Locomotor activity0.50.72.1-1.0-1.1-1.5-0.7-0.8-0.90.2-0.2-0.4-0.1-0.80.91.3-0.9-0.9
Locomotor testing distance0.91.43.7-1.4-1.4-1.9-1.0-1.2-1.3-0.10.0-0.80.0-1.01.21.9-1.2-1.3
Locomotor testing rearing0.30.41.8-0.4-0.3-0.5-0.2-0.3-0.2-1.11.0-1.40.9-0.00.40.9-0.1-0.4
Light reinforcement 10.30.51.6-0.8-0.8-0.7-0.3-0.7-0.7-0.20.1-0.80.2-0.60.81.3-0.7-0.8
Light reinforcement 20.00.10.4-0.1-0.2-0.60.30.2-0.10.1-0.2-0.40.2-0.00.10.3-0.1-0.1
Reaction time number correct0.10.10.50.20.30.7-0.4-0.20.2-0.60.60.3-0.10.1-0.1-0.30.30.1
Reaction time mean minus median1.01.44.21.00.80.31.61.40.8-1.00.9-2.01.71.1-1.1-0.50.91.2
Reaction time mean minus median AUC1.62.06.81.11.00.51.81.51.0-1.41.4-2.62.11.3-1.3-0.51.01.3
Reaction time num false alarms0.30.40.90.60.40.30.90.70.6-0.50.5-0.90.90.7-0.7-0.50.50.6
Reaction time num false alarms AUC0.40.51.10.70.50.41.00.90.8-0.40.4-0.90.90.8-0.7-0.70.60.6
Reaction time trials correct on left0.10.10.50.20.30.7-0.4-0.20.2-0.60.60.3-0.10.1-0.1-0.30.30.1
Reaction time trials on left0.10.10.50.20.40.7-0.4-0.20.3-0.60.60.3-0.00.1-0.1-0.30.30.2
Reaction time mean0.30.42.90.20.0-0.50.80.60.0-0.50.4-1.71.10.4-0.40.20.10.4
Reaction time mean AUC0.40.53.10.30.1-0.40.90.80.1-0.50.4-1.81.20.4-0.60.10.20.6
Median of all reaction times0.20.31.7-0.3-0.4-0.80.30.1-0.4-0.10.1-1.30.7-0.10.10.7-0.3-0.1
Reaction time omissions0.20.31.20.40.2-0.11.10.80.30.0-0.1-1.10.70.5-0.5-0.20.30.5
Reaction time false alarm rate0.20.21.00.40.1-0.21.00.70.40.1-0.1-0.80.60.5-0.5-0.30.30.4
Reaction time premature initiation rate0.40.51.00.90.70.60.80.90.7-0.40.4-0.50.60.7-1.0-0.90.70.9
Reaction time premature initiations0.60.81.31.10.91.00.70.90.9-0.70.7-0.50.70.9-1.2-1.10.91.1
Std. dev. reaction times0.70.93.00.80.60.21.51.30.7-0.60.5-1.71.40.9-0.9-0.50.61.0
Reaction time trials completed0.10.10.50.20.40.7-0.4-0.20.3-0.60.60.3-0.00.1-0.1-0.30.30.2
Reaction time trials AUC0.10.10.50.20.40.7-0.4-0.20.3-0.70.70.20.00.2-0.1-0.30.30.2
Social response proportion0.80.92.31.00.80.81.51.31.10.5-0.4-0.10.41.0-0.8-1.30.90.9
Social responses0.10.10.30.30.00.20.50.30.20.3-0.3-0.10.20.3-0.2-0.40.20.2
Social time0.20.20.90.2-0.0-0.5-0.2-0.0-0.0-0.80.7-0.90.60.1-0.30.20.10.3
Conditioned locomotion1.21.42.2-1.1-1.1-1.5-1.4-1.1-1.21.1-1.11.3-1.3-1.21.10.9-1.1-1.1
Cocaine response after cond. corrected5.86.59.3-2.5-2.6-3.1-2.6-2.6-2.62.4-2.52.4-2.7-2.62.52.2-2.6-2.5
Cocaine response after cond. not corrected3.43.85.7-1.8-1.9-2.4-1.8-1.8-1.92.2-2.22.0-2.1-1.91.81.5-1.9-1.8
Cocaine response before conditioning2.22.74.01.71.71.72.01.91.8-1.11.1-1.41.61.8-1.6-1.61.81.7
Saline control response0.20.31.00.40.40.60.00.20.4-1.01.0-0.50.60.4-0.3-0.20.50.3
Condit. Reinf. active minus inactive responses0.10.10.3-0.5-0.4-0.20.1-0.2-0.30.3-0.3-0.1-0.1-0.30.40.5-0.4-0.4
Condit. Reinf. active-inactive response ratio0.30.30.8-0.7-0.7-0.8-0.2-0.5-0.60.2-0.2-0.3-0.1-0.50.60.9-0.7-0.6
Condit. Reinf. active responses0.00.00.2-0.1-0.00.20.30.10.0-0.10.1-0.50.30.10.10.2-0.0-0.1
Condit. Reinf. inactive responses0.30.40.80.50.60.90.40.40.5-0.80.8-0.80.70.5-0.4-0.20.50.4
Condit. Reinf. lever presses0.81.01.81.00.91.01.31.21.0-0.70.7-1.11.11.1-1.1-0.91.01.0
Condit. Reinf. lever reinforcers received0.10.10.40.10.20.50.40.30.2-0.40.4-0.60.50.3-0.10.00.20.2
Pavlov. Cond. lever latency0.50.71.10.90.90.70.81.10.9-0.50.5-0.50.70.9-0.9-1.00.90.9
Pavlov. Cond. magazine entry latency0.40.51.10.90.61.00.80.80.8-0.00.0-0.10.30.7-0.9-1.00.70.8
Pavlov. Cond. change in total contacts0.10.20.4-0.5-0.6-0.1-0.1-0.4-0.40.5-0.5-0.0-0.2-0.40.50.6-0.5-0.5
Pavlov. Cond. index score0.20.30.8-0.5-0.7-0.1-0.3-0.5-0.50.9-0.90.6-0.6-0.50.50.4-0.6-0.5
Pavlov. Cond. latency score0.20.20.8-0.3-0.4-0.0-0.0-0.2-0.30.9-0.90.6-0.5-0.30.30.1-0.4-0.3
Pavlov. Cond. lever contacts0.40.60.9-0.8-0.9-0.6-0.7-0.9-0.80.5-0.50.4-0.6-0.80.80.9-0.8-0.8
Pavlov. Cond. magazine entry number0.10.10.4-0.10.1-0.3-0.1-0.10.0-0.60.6-0.50.30.00.10.30.1-0.1
Pavlov. Cond. intertrial magazine entries1.82.34.31.41.72.11.31.41.5-1.71.7-1.31.51.5-1.4-1.31.61.4
Pavlov. Cond. lever-magazine prob. diff.0.30.41.0-0.5-0.7-0.1-0.3-0.5-0.61.0-1.00.7-0.7-0.60.50.4-0.7-0.6
Pavlov. Cond. response bias0.40.50.8-0.8-0.9-0.6-0.6-0.9-0.80.6-0.60.5-0.6-0.80.70.8-0.8-0.8
Conditioned reinforcement - actives0.80.81.9-1.0-1.1-1.4-0.3-0.5-1.00.8-0.9-0.1-0.4-0.90.91.2-1.1-0.9
Conditioned reinforcement - inactives0.70.82.90.40.70.90.20.10.6-1.71.7-1.21.10.7-0.4-0.00.70.4
Conditioned locomotion3.13.75.8-2.1-2.4-2.2-0.9-1.3-2.02.4-2.40.8-1.4-1.91.92.1-2.3-2.0
Intermittent access intake day 1-15 change2.42.43.6-1.7-1.6-1.2-1.0-1.4-1.41.7-1.71.3-1.5-1.51.71.6-1.6-1.9
Intermittent access intake escalation2.32.33.4-1.7-1.6-1.3-0.8-1.3-1.41.8-1.81.1-1.4-1.41.71.6-1.6-1.8
Intermittent access intake escalation 21.91.92.8-1.6-1.3-1.0-0.8-1.2-1.21.5-1.51.2-1.3-1.31.61.4-1.4-1.7
Intermitt. access day 1 inactive lever presses0.40.42.10.10.60.8-0.1-0.10.4-1.41.4-0.60.60.4-0.10.10.50.2
Intermitt. access day 15 inactive lever presses0.60.72.0-0.8-0.5-0.6-0.8-1.1-0.6-1.11.1-0.90.4-0.50.81.4-0.5-0.8
Intermitt. access escalation Index2.01.85.2-1.1-1.4-1.9-0.3-0.4-1.22.3-2.30.9-1.2-1.11.00.9-1.3-1.1
Intermittent access day 1 total infusions0.40.50.90.80.70.20.50.70.5-0.80.8-0.90.80.6-0.9-0.60.61.0
Intermittent access day 15 total infusions0.10.10.4-0.4-0.4-0.60.1-0.0-0.30.5-0.5-0.1-0.1-0.30.30.5-0.4-0.4
Intermittent access terminal intake (last 3 days)0.10.10.4-0.5-0.4-0.6-0.1-0.2-0.40.1-0.1-0.30.0-0.30.30.6-0.4-0.4
Intermittent access total infusions0.00.00.10.1-0.0-0.30.10.1-0.00.1-0.1-0.20.10.0-0.2-0.0-0.00.1
Intermittent access day 1 locomotion0.30.30.60.50.40.20.80.80.5-0.40.3-0.80.70.6-0.6-0.40.50.7
Intermittent access day 15 total locomotion0.20.30.5-0.7-0.7-0.50.0-0.2-0.40.6-0.6-0.1-0.1-0.40.60.7-0.5-0.6
Intermittent access total locomotion0.50.51.2-0.8-0.9-0.80.2-0.1-0.61.1-1.1-0.0-0.3-0.50.70.8-0.8-0.7
Intermittent access standard deviation2.12.23.5-1.8-1.6-1.2-0.8-1.4-1.31.6-1.61.3-1.4-1.41.91.6-1.4-1.9
Cocaine induced anxiety0.10.10.3-0.3-0.3-0.1-0.2-0.3-0.20.5-0.50.5-0.4-0.30.30.2-0.3-0.3
Post-drug Anxiety0.70.82.10.60.71.00.50.40.7-1.41.4-1.31.20.7-0.6-0.20.70.6
Baseline Anxiety0.50.52.5-0.00.20.3-0.2-0.30.0-1.61.5-1.31.00.20.00.60.20.1
Lifetime Intake0.10.10.20.20.2-0.20.30.30.1-0.10.1-0.40.30.2-0.4-0.20.20.3
Incentive Sensitization - Responses0.10.10.2-0.3-0.20.0-0.1-0.2-0.2-0.10.1-0.30.1-0.10.30.5-0.2-0.4
Incentive Sensitization - Breakpoint0.10.10.4-0.5-0.4-0.2-0.3-0.4-0.40.2-0.20.0-0.1-0.40.50.6-0.4-0.6
Progressive ratio test 1 active lever presses0.30.30.90.70.40.00.60.80.30.0-0.0-0.50.40.5-1.0-0.70.40.9
Progressive ratio test 1 breakpoint0.50.51.40.90.60.30.70.90.6-0.20.2-0.50.50.6-1.2-0.90.61.1
Progressive ratio test 1 inactive lever presses0.10.10.2-0.1-0.2-0.2-0.4-0.3-0.3-0.30.3-0.20.0-0.20.00.3-0.20.0
Progressive ratio test 2 active lever presses0.20.31.00.40.30.10.60.60.3-0.50.4-1.00.80.4-0.5-0.10.30.5
Progressive ratio test 2 breakpoint0.10.10.60.30.20.00.40.40.2-0.30.3-0.80.60.3-0.5-0.10.20.3
Progressive ratio test 2 inactive lever presses0.20.21.00.10.40.3-0.1-0.10.2-1.01.0-0.60.50.2-0.10.10.30.2
Total sessions with >9 infusions0.30.31.1-0.5-0.5-0.90.50.2-0.41.0-1.1-0.1-0.2-0.30.30.4-0.5-0.3
Short access day 1 total inactive lever presses3.64.08.11.62.02.01.51.41.9-2.82.9-2.32.41.9-1.6-1.12.01.7
Short access day 10 total inactive lever presses0.80.93.50.60.91.4-0.10.10.7-1.91.9-0.80.90.7-0.5-0.20.90.5
Short access day 1 total infusions0.10.10.60.10.3-0.10.70.50.3-0.20.2-0.80.60.4-0.20.10.20.2
Short access day 10 total infusions0.20.30.8-0.5-0.5-0.9-0.3-0.4-0.50.6-0.70.3-0.4-0.50.40.4-0.5-0.4
Short access total infusions0.00.00.1-0.1-0.0-0.4-0.1-0.0-0.10.1-0.10.1-0.1-0.1-0.1-0.0-0.10.1
Short access day 1 locomotion0.70.81.3-1.1-0.9-0.9-0.0-0.5-0.71.1-1.10.4-0.6-0.81.01.1-0.9-1.0
Short access day 10 total locomotion0.50.61.7-0.9-1.0-0.20.5-0.0-0.41.3-1.30.1-0.3-0.40.90.8-0.7-0.9
Short access total locomotion1.01.02.0-1.2-1.1-0.7-0.3-0.6-0.81.4-1.40.8-0.9-0.91.10.9-1.0-1.1
Compulsive drug intake7.57.59.63.12.82.32.62.92.8-2.42.4-2.32.62.9-3.1-2.82.93.0
One hour access (0.3 mA shock)0.70.91.21.00.90.60.70.80.8-1.11.1-1.11.10.9-1.1-0.70.91.0
One hour access (shock baseline)2.22.63.4-1.8-1.7-1.6-1.4-1.7-1.71.3-1.31.0-1.4-1.71.81.8-1.7-1.8
Number of responses in last shaping day0.30.31.2-0.1-0.1-0.1-1.1-0.8-0.4-0.90.9-0.0-0.1-0.3-0.10.3-0.20.1
Context. condit. distance diff. score0.30.30.9-0.4-0.4-0.8-0.9-0.7-0.60.3-0.30.7-0.7-0.60.40.3-0.5-0.4
Locomotion velocity, session 10.40.40.7-0.7-0.7-0.5-0.3-0.5-0.70.8-0.80.4-0.6-0.60.60.6-0.7-0.7
Locomotion distance, session 12.02.64.71.71.62.02.21.91.9-0.50.5-0.61.11.7-1.7-2.01.71.7
Locomotion velocity, session 20.70.92.01.00.91.11.21.21.10.3-0.30.20.31.0-0.9-1.41.00.9
Locomotion distance, session 22.53.66.32.01.92.42.52.22.2-0.70.7-0.91.42.1-2.0-2.22.01.9
Locomotion velocity, session 30.00.00.30.10.10.2-0.2-0.00.10.1-0.10.6-0.3-0.00.0-0.30.10.0
Locomotion distance, session 32.52.74.51.91.91.81.61.81.8-1.01.0-0.51.11.7-1.8-2.11.81.8
Stereotopy head waving bouts, day 33.94.76.2-2.3-2.3-2.1-2.5-2.5-2.31.5-1.61.4-1.8-2.32.42.4-2.3-2.3
Stereotopy head waving duration, day 33.13.74.3-2.0-2.1-1.7-2.0-2.1-2.01.7-1.71.6-1.8-2.02.11.9-2.0-2.1
Locomotion velocity, session 71.11.21.91.21.21.41.01.11.2-0.70.7-0.20.61.1-1.2-1.41.21.2
Locomotion distance, session 74.35.57.42.62.62.52.62.62.6-1.41.5-1.31.92.5-2.5-2.72.62.5
Stereotopy head waving bouts, day 70.50.61.1-0.9-0.9-1.0-0.8-0.9-0.80.2-0.20.0-0.3-0.70.91.1-0.8-0.9
Stereotopy head waving duration, day 70.20.30.7-0.6-0.6-0.7-0.7-0.6-0.5-0.10.1-0.2-0.0-0.50.60.8-0.5-0.6
Locomotion velocity, session 80.30.31.3-0.3-0.3-0.1-0.9-0.6-0.40.4-0.41.1-0.9-0.60.3-0.0-0.4-0.3
Locomotion distance, session 80.50.71.61.00.91.10.91.00.9-0.10.10.10.30.8-1.0-1.30.91.0
Degree of sensitization distance0.00.00.00.10.00.2-0.0-0.00.10.1-0.10.2-0.10.0-0.0-0.10.00.0
Degree of sensitization stereotypy0.30.31.50.10.2-0.20.20.20.2-1.11.0-1.20.90.3-0.10.30.30.2
Condit. Reinf. active minus inactive responses0.20.20.60.30.30.20.60.60.4-0.30.3-0.80.70.5-0.4-0.20.40.3
Condit. Reinf. active-inactive response ratio0.20.20.4-0.5-0.5-0.7-0.1-0.2-0.30.4-0.4-0.2-0.0-0.30.50.6-0.4-0.5
Condit. Reinf. active responses0.20.20.90.20.30.10.70.50.4-0.40.4-0.90.70.5-0.20.00.40.2
Condit. Reinf. inactive responses0.50.51.10.60.80.40.80.60.6-1.01.0-1.10.90.7-0.6-0.30.70.6
Incentive salience index mean0.50.51.40.50.50.51.00.90.7-0.50.5-1.21.00.8-0.6-0.30.60.6
Condit. Reinf. lever presses1.11.52.91.01.01.11.31.31.2-1.31.3-1.71.61.2-1.2-0.71.11.1
Time in familiar zone, hab. session 11.01.03.10.70.90.50.40.30.6-1.81.7-1.51.30.7-0.7-0.30.80.8
Time in novel zone, hab. session 13.03.03.5-1.8-1.9-1.7-1.7-1.7-1.71.7-1.71.5-1.7-1.81.81.6-1.8-1.8
Total zone transitions, hab. session 15.78.09.53.03.03.12.92.93.0-2.32.4-2.02.52.9-3.1-3.03.03.0
Total locomotion distance, hab. session 12.53.65.01.92.02.22.11.92.0-1.71.7-1.71.92.0-1.9-1.82.01.9
Locomotion velocity, hab. session 13.14.56.82.22.32.62.42.32.3-1.51.5-1.41.82.2-2.2-2.22.22.2
Time in familiar zone, hab. session 20.40.41.1-0.7-0.5-0.6-1.1-0.9-0.7-0.50.5-0.1-0.2-0.70.71.0-0.6-0.6
Time in novel zone, hab. session 20.10.10.20.30.20.30.30.30.20.3-0.30.3-0.10.2-0.3-0.50.20.2
Total zone transitions, hab. session 21.92.43.81.51.51.52.01.71.6-1.11.1-1.61.71.7-1.6-1.41.61.5
Total locomotion distance, hab. session 20.10.10.40.10.10.60.60.30.20.1-0.1-0.30.20.2-0.1-0.10.10.1
Locomotion velocity, hab. session 20.10.10.60.20.20.70.80.40.30.4-0.4-0.10.10.3-0.2-0.30.20.2
Novel to familiar place preference ratio0.60.71.91.11.00.70.50.80.9-0.20.20.20.20.8-1.0-1.40.91.0
Novelty place preference0.80.82.11.21.10.80.60.91.0-0.30.30.10.30.9-1.1-1.41.01.1
Time in novel zone, NPP test0.60.61.51.01.00.60.40.70.8-0.50.50.00.30.8-1.0-1.20.91.0
Total zone transitions, NPP test3.24.67.22.22.12.42.72.52.4-1.51.5-1.82.12.3-2.2-2.12.22.2
Total locomotion distance, NPP test0.81.12.50.91.01.61.41.11.1-0.80.8-0.91.01.1-1.0-0.91.00.9
Locomotion velocity, NPP test1.21.73.81.31.32.01.81.51.5-0.60.6-0.81.11.4-1.2-1.31.31.2
Pavlov. Cond. lever latency1.62.03.5-1.2-1.2-1.3-1.2-1.2-1.31.9-1.91.8-1.8-1.41.30.8-1.3-1.3
Pavlov. Cond. magazine entry latency0.20.21.60.10.0-0.20.50.20.1-0.60.6-1.30.90.3-0.20.30.10.1
Pavlov. Cond. change in total contacts2.93.06.21.51.61.11.71.61.6-2.12.1-2.52.31.7-1.6-1.01.61.6
Pavlov. Cond. index score0.91.13.70.70.70.61.00.80.8-1.51.5-1.91.60.9-0.9-0.20.80.8
Pavlov. Cond. latency score0.91.13.10.80.70.81.00.90.9-1.41.4-1.81.51.0-0.9-0.40.90.9
Pavlov. Cond. lever contacts2.32.74.81.41.41.31.51.51.5-2.02.0-2.22.11.6-1.6-1.01.51.5
Pavlov. Cond. magazine entry number0.81.04.5-0.4-0.4-0.2-0.8-0.5-0.51.5-1.52.1-1.6-0.70.5-0.2-0.5-0.5
Pavlov. Cond. intertrial magazine entries0.40.40.90.80.90.70.50.70.7-0.50.5-0.10.30.7-0.6-0.80.80.7
Pavlov. Cond. lever-magazine prob. diff.0.81.13.70.70.60.41.00.80.7-1.41.4-1.91.60.9-0.9-0.20.70.8
Pavlov. Cond. response bias1.11.34.60.70.70.51.00.80.8-1.61.6-2.11.81.0-0.9-0.10.80.8
Bone: apparent density1.32.23.0-1.7-1.5-1.6-1.4-1.6-1.61.1-1.11.1-1.3-1.61.71.7-1.5-1.7
Bone surface0.50.81.6-0.9-0.7-0.7-1.0-0.9-0.80.9-0.91.3-1.2-0.91.00.6-0.7-0.9
Bone volume1.32.22.7-1.5-1.3-1.3-1.5-1.5-1.51.4-1.41.6-1.7-1.51.61.2-1.4-1.5
Bone: connectivity density0.10.20.5-0.5-0.2-0.7-0.4-0.4-0.4-0.20.2-0.20.0-0.30.50.7-0.3-0.5
Bone: cortical apparent density7.69.916.33.13.12.32.32.62.8-4.04.0-3.73.73.0-3.2-2.23.03.2
Bone: cortical area0.10.20.7-0.3-0.20.2-0.5-0.3-0.30.5-0.50.8-0.7-0.40.40.0-0.3-0.3
Bone: cortical porosity0.40.51.1-0.7-0.7-1.0-0.5-0.6-0.70.7-0.70.4-0.5-0.60.70.7-0.7-0.7
Bone: cortical porosity0.40.40.7-0.6-0.6-0.8-0.4-0.5-0.60.8-0.80.5-0.6-0.60.60.6-0.6-0.7
Bone: cortical thickness0.10.20.50.60.60.7-0.10.30.5-0.50.50.10.20.4-0.5-0.70.50.6
Bone: cortical thickness1.01.12.11.11.10.91.51.41.3-0.20.2-0.60.81.3-1.1-1.31.21.1
Bone: cortical tissue density8.010.416.83.23.22.42.52.72.9-4.14.1-3.83.83.1-3.3-2.33.13.3
Bone: elastic displacement0.10.20.4-0.4-0.5-0.2-0.2-0.3-0.40.6-0.60.3-0.4-0.40.30.3-0.5-0.4
Bone: elastic work0.10.10.60.0-0.10.10.00.1-0.10.8-0.80.7-0.5-0.1-0.0-0.3-0.10.0
Bone: endosteal estimation0.61.23.9-0.9-0.8-0.7-0.3-0.4-0.72.0-2.01.6-1.4-0.81.00.3-0.8-1.0
Bone: endosteal perimeter0.71.42.7-1.2-1.0-0.7-0.7-0.9-0.91.7-1.61.5-1.4-1.01.30.7-1.0-1.2
Bone: final force0.20.40.6-0.7-0.5-0.6-0.5-0.5-0.60.7-0.70.7-0.7-0.60.80.5-0.6-0.7
Bone: final moment0.30.60.9-0.7-0.6-0.7-0.6-0.6-0.60.9-0.90.9-0.9-0.70.90.5-0.7-0.7
Bone: marrow area0.40.93.1-0.7-0.7-0.6-0.1-0.3-0.61.8-1.71.4-1.2-0.70.80.2-0.7-0.8
Bone: maximum diameter0.50.91.4-1.1-0.9-0.7-0.7-0.8-0.91.2-1.21.0-1.0-0.91.20.8-0.9-1.1
Bone: maximum force0.81.32.6-1.0-0.9-0.9-0.9-0.8-1.01.6-1.61.6-1.5-1.11.10.6-1.0-1.0
Bone: maximum moment0.91.63.4-1.0-0.9-1.0-1.0-0.9-1.01.8-1.81.9-1.7-1.11.20.5-1.0-1.1
Bone: minimum diameter0.20.41.6-0.3-0.30.1-0.2-0.1-0.21.2-1.21.3-1.0-0.30.4-0.3-0.3-0.3
Bone: periosteal estimation0.61.12.4-1.0-0.9-0.6-0.7-0.7-0.81.6-1.51.5-1.4-0.91.10.5-0.9-1.0
Bone: periosteal perimeter0.61.12.6-0.9-0.8-0.4-1.1-1.0-0.81.2-1.21.6-1.4-1.01.00.5-0.8-1.0
Bone: post-yield work0.30.41.2-0.4-0.2-0.7-0.8-0.6-0.50.6-0.61.1-0.9-0.60.50.1-0.4-0.4
Bone: stiffness0.10.20.6-0.3-0.1-0.4-0.2-0.1-0.30.7-0.70.8-0.6-0.30.40.0-0.2-0.3
Bone: tissue strength0.10.10.5-0.2-0.2-0.3-0.7-0.5-0.5-0.00.00.4-0.4-0.40.10.2-0.3-0.2
Bone: trabecular number0.50.82.0-1.1-0.9-1.0-0.7-1.0-1.00.1-0.2-0.1-0.3-0.91.21.4-0.9-1.1
Bone: trabecular spacing0.00.10.20.1-0.00.5-0.10.00.1-0.40.4-0.30.30.1-0.2-0.00.00.2
Bone: trabecular thickness1.92.34.0-1.3-1.3-1.4-1.5-1.4-1.41.7-1.72.0-1.9-1.51.40.9-1.4-1.4
Bone: trabecular tissue density0.10.10.70.30.30.80.30.40.4-0.30.3-0.20.30.3-0.4-0.40.30.3
Breakpoint value in progressive ratio session3.64.05.12.22.22.11.71.92.2-1.81.8-1.31.72.1-2.1-2.22.32.2
Distance traveled before self-admin0.60.61.80.70.71.01.41.10.9-0.00.0-0.50.70.9-0.7-0.80.70.7
Distance traveled after self-admin1.21.33.6-0.9-1.0-1.5-0.5-0.4-1.01.9-1.91.1-1.2-1.00.90.7-1.1-0.9
Delta time in closed arm before/after self-admin0.10.10.20.40.4-0.2-0.5-0.10.0-0.30.30.2-0.10.0-0.4-0.30.20.3
Delta time in open arm before/after self-admin0.20.20.80.20.40.60.10.20.4-0.90.9-0.60.60.3-0.2-0.20.40.4
Diff in mean of infusions in LGA sessions0.70.82.00.61.00.30.60.60.8-1.41.4-1.21.20.9-0.5-0.40.90.7
Extinction: sum of active levers before priming1.01.01.81.21.00.71.01.21.0-0.40.4-0.50.71.0-1.3-1.31.01.2
Active lever presses in extinction session 60.10.10.2-0.4-0.4-0.2-0.1-0.2-0.30.4-0.40.0-0.2-0.30.40.5-0.3-0.4
Delta distance traveled before/after self-admin2.22.34.8-1.4-1.5-2.2-1.7-1.3-1.71.4-1.41.2-1.5-1.61.31.4-1.7-1.3
Delta ambulatory time before/after self-admin2.62.84.6-1.5-1.6-2.1-2.0-1.7-1.91.4-1.41.5-1.7-1.81.51.4-1.8-1.5
Time in closed arm before self-admin1.21.42.5-1.4-1.2-0.3-1.6-1.5-1.20.4-0.41.1-1.1-1.31.51.3-1.2-1.4
Time in closed arm after self-admin1.11.13.7-0.8-0.7-0.7-1.9-1.5-1.00.2-0.21.5-1.3-1.10.90.7-0.9-0.9
Time in open arm before self-admin0.40.41.00.80.6-0.20.70.80.4-0.40.3-0.70.60.5-1.0-0.60.50.9
Time in open arm after self-admin0.90.92.20.80.80.60.70.80.7-1.31.3-1.51.30.8-1.0-0.50.71.0
Sum of active levers in priming session hrs 5-63.53.55.11.91.81.32.22.12.0-1.41.4-1.92.02.1-1.9-1.71.91.9
Time to tail flick, vehicle, before self-admin2.12.13.41.41.40.81.11.21.3-1.81.8-1.61.61.5-1.4-1.21.51.5
Time to tail flick, vehicle, after self-admin0.20.20.4-0.5-0.2-0.4-0.6-0.5-0.4-0.10.10.3-0.3-0.40.50.6-0.4-0.4
Time to tail flick, test, before self-admin0.10.10.4-0.3-0.4-0.0-0.6-0.6-0.3-0.10.10.3-0.3-0.30.30.3-0.2-0.3
Time to tail flick, test, after self-admin0.10.10.4-0.1-0.1-0.6-0.4-0.2-0.30.5-0.50.6-0.6-0.3-0.0-0.1-0.3-0.1
Delta time to tail flick, vehicle, before/after SA1.51.52.1-1.3-1.1-0.8-1.4-1.4-1.30.9-0.91.2-1.3-1.31.31.3-1.3-1.3
Delta time to tail flick, test, before/after SA0.30.20.70.50.50.10.80.80.40.4-0.40.00.10.4-0.5-0.70.40.5
Ambulatory time before self-admin0.40.41.20.50.50.91.10.90.70.1-0.1-0.40.50.7-0.5-0.60.50.5
Ambulatory time after self-admin1.92.15.8-1.1-1.3-1.7-0.8-0.6-1.22.4-2.41.7-1.7-1.31.10.6-1.4-1.1
Total heroin consumption2.02.44.71.51.51.21.01.11.3-2.22.2-1.81.71.4-1.5-1.11.51.5
Area under the delay curve0.20.20.50.40.50.70.60.70.60.3-0.30.3-0.00.5-0.4-0.70.50.4
Delay disc. indifference point, 0s delay0.80.91.40.91.11.20.60.81.0-1.11.1-0.60.80.9-0.8-0.81.00.9
Delay disc. indifference point, 16s delay0.50.51.3-0.6-0.6-0.4-0.4-0.4-0.51.2-1.11.2-1.0-0.60.60.3-0.6-0.6
Delay disc. indifference point, 2s delay0.20.20.60.40.40.80.40.50.50.1-0.10.4-0.10.3-0.4-0.60.40.3
Delay disc. indifference point, 24s delay0.40.40.90.70.60.51.01.00.70.1-0.1-0.30.40.7-0.7-0.80.70.6
Delay disc. indifference point, 4s delay2.62.75.11.81.92.01.71.82.0-0.60.6-0.00.81.7-1.8-2.21.91.8
Delay disc. indifference point, 8s delay0.10.10.40.20.30.30.60.60.40.1-0.1-0.10.20.4-0.3-0.40.30.4
Delay discount exponential model param0.30.30.7-0.5-0.6-0.8-0.7-0.8-0.7-0.40.4-0.40.1-0.50.50.9-0.6-0.5
Delay discount hyperbolic model param0.50.51.1-0.7-0.8-1.0-0.8-0.9-0.8-0.20.1-0.3-0.1-0.70.71.0-0.8-0.7
Fecal boli incidents, locomotor time 12.93.24.3-1.9-1.8-1.4-2.0-2.1-1.91.2-1.21.6-1.8-1.92.01.9-1.8-1.9
Change in fecal boli incidents, locomotor task2.32.23.21.71.61.31.31.51.5-1.31.3-1.01.21.5-1.7-1.71.51.8
Time >=10cm from walls, locomotor time 10.40.41.40.50.50.00.10.50.4-1.01.0-1.21.00.6-0.6-0.20.50.6
Bouts of movement, locomotor time 10.10.10.4-0.2-0.2-0.0-0.3-0.3-0.20.5-0.40.6-0.5-0.30.20.0-0.2-0.2
Total resting periods, locomotor time 10.30.31.2-0.3-0.3-0.2-0.5-0.5-0.40.7-0.71.1-0.9-0.50.40.1-0.4-0.4
Rest time, locomotor task time 10.30.30.8-0.5-0.4-0.2-0.3-0.5-0.50.8-0.80.9-0.8-0.50.50.4-0.5-0.6
Distance moved, locomotor task time 11.01.11.61.11.00.71.21.31.1-0.70.7-1.01.11.2-1.1-1.21.11.2
Vertical activity count, locomotor time 10.40.40.70.70.40.00.40.70.5-0.50.5-0.80.70.6-0.8-0.70.50.8
Time >=10cm from walls, locomotor time 20.60.71.00.80.80.60.60.70.7-1.01.0-1.01.00.8-0.8-0.70.80.9
Bouts of movement, locomotor time 20.10.10.2-0.4-0.3-0.3-0.5-0.4-0.30.1-0.10.1-0.2-0.30.40.4-0.3-0.4
Total resting periods, locomotor time 20.10.10.3-0.4-0.3-0.2-0.5-0.5-0.4-0.00.00.1-0.2-0.40.40.5-0.3-0.4
Rest time, locomotor task time 21.21.43.21.11.21.20.60.71.0-1.81.8-1.31.31.1-1.1-0.71.11.2
Distance moved, locomotor task time 20.30.41.10.40.10.20.40.50.31.0-1.00.9-0.50.2-0.4-1.00.20.4
Vertical activity count, locomotor time 20.50.62.50.0-0.4-0.60.00.3-0.11.6-1.61.2-0.9-0.3-0.1-0.5-0.3-0.0
Weight adjusted by age0.70.81.31.10.81.00.50.90.9-1.01.0-0.70.80.9-1.2-1.00.91.0
Seeking ratio, delayed vs. immediate footshock0.30.41.0-0.5-0.4-0.9-1.0-0.9-0.7-0.20.20.2-0.4-0.60.60.7-0.5-0.5
Locomotion in novel chamber0.60.82.00.91.00.8-0.10.30.7-1.41.4-0.40.60.7-0.9-0.80.91.0
Locomotion in novel chamber post-restriction1.21.52.6-1.3-1.3-1.2-1.6-1.5-1.50.3-0.30.3-0.8-1.41.21.5-1.4-1.2
Progressive ratio0.20.21.4-0.00.41.2-0.5-0.40.3-0.60.70.4-0.10.10.1-0.10.3-0.1
Food seeking constrained by brief footshock0.60.71.3-1.0-0.8-0.8-0.3-0.4-0.71.1-1.10.5-0.7-0.71.10.9-0.8-1.0
Seeking ratio, punishment vs. effort0.30.31.90.0-0.3-1.40.70.6-0.31.0-1.0-0.50.1-0.1-0.10.1-0.30.1
Run reversals in cocaine runway, females0.30.30.90.60.30.10.60.80.40.7-0.70.4-0.10.4-0.7-1.00.40.6
Run reversals in cocaine runway, males1.01.02.2-0.8-0.9-0.6-1.5-1.4-1.0-1.01.0-0.70.1-0.90.71.5-0.9-0.8
Latency to leave start box in cocaine runway3.33.66.3-1.9-1.5-1.7-2.5-2.4-1.91.2-1.22.2-2.1-2.02.11.6-1.8-1.9
Latency to leave start box in cocaine runway, F5.05.58.6-2.3-2.0-1.9-2.9-2.8-2.41.7-1.82.8-2.8-2.52.41.9-2.3-2.3
Latency to leave start box in cocaine runway, M0.70.61.2-0.9-0.6-1.1-0.7-0.8-0.70.7-0.70.6-0.7-0.71.10.8-0.7-1.0
Cd content in liver0.70.71.80.80.91.00.20.40.7-1.41.4-0.70.80.7-0.8-0.70.80.8
Co content in liver0.10.10.3-0.1-0.1-0.2-0.4-0.4-0.20.3-0.30.6-0.5-0.20.2-0.0-0.1-0.2
Cu content in liver2.12.54.61.41.70.92.11.91.7-1.31.3-1.81.81.8-1.3-1.21.71.4
Fe content in liver1.01.22.41.21.41.11.21.41.3-0.40.4-0.10.51.2-1.1-1.61.31.2
K content in liver0.20.20.5-0.5-0.4-0.6-0.1-0.3-0.30.7-0.70.5-0.5-0.30.70.4-0.4-0.5
Mg content in liver0.60.61.00.70.90.70.70.70.8-1.01.0-0.80.90.9-0.6-0.60.90.7
Mn content in liver3.13.56.61.61.61.52.21.91.8-1.91.9-2.62.41.9-1.7-1.21.81.7
Na content in liver0.70.81.5-1.1-1.1-1.2-0.3-0.6-0.80.8-0.8-0.1-0.3-0.71.11.2-0.9-1.1
Rb content in liver0.40.52.10.00.50.4-0.1-0.10.1-1.51.4-1.00.80.20.00.40.30.1
Se content in liver0.20.30.6-0.6-0.4-0.1-0.7-0.7-0.50.1-0.10.5-0.5-0.50.70.6-0.4-0.6
Sr content in liver1.71.62.81.51.11.41.41.51.4-0.40.4-0.60.91.3-1.5-1.71.31.5
Zn content in liver0.10.10.2-0.2-0.2-0.3-0.4-0.4-0.2-0.50.5-0.40.2-0.20.20.4-0.2-0.2