Hub : Genes

Slc16a3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	ENSRNOG00000036677	0.06	0.04	2.9e-03	0.04	0.05	0.04	0.04	2.1e-03	1.6e-03	2.9e-03	3.6e-03
2	Brain	gene expression	ENSRNOG00000036677	0.03	0.02	6.5e-03	0.01	0.01	0.01	0.01	5.9e-02	2.9e-02	2.4e-02	6.1e-02
3	Brain	mRNA stability	ENSRNOG00000036677	0.04	0.03	1.5e-03	0.02	0.03	0.03	0.03	4.7e-03	4.6e-04	1.2e-03	1.2e-03
4	NAcc	gene expression	ENSRNOG00000036677	0.26	0.11	0.0e+00	0.22	0.22	0.19	0.23	1.8e-16	3.8e-16	2.1e-14	9.3e-17
5	NAcc	isoform ratio	ENSRNOT00000054939	0.15	0.09	1.5e-08	0.12	0.11	0.11	0.12	2.6e-09	2.3e-08	8.4e-09	4.9e-09
6	NAcc	isoform ratio	ENSRNOT00000086096	0.15	0.09	1.2e-08	0.12	0.11	0.12	0.12	2.0e-09	1.6e-08	6.9e-09	3.6e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	0.4	1.3	2.0	-1.2	-0.5	-0.7	-1.3	-1.4	1.4
BMI without tail	9.1	19.0	20.9	-4.6	-4.4	-4.5	-3.9	-4.4	4.4
Body weight	3.1	12.9	17.5	-3.6	-2.5	-2.5	-4.2	-4.2	4.2
Epididymis fat weight	1.0	2.4	2.8	-1.7	-1.4	-1.6	-1.5	-1.6	1.6
Glucose	5.9	9.0	14.7	3.2	3.8	3.7	1.8	2.4	-2.4
Heart weight	0.3	0.4	0.7	-0.5	-0.0	-0.0	-0.9	-0.8	0.8
Left kidney weight	0.1	0.3	1.1	0.4	0.7	1.0	-0.2	-0.0	0.0
Right kidney weight	0.1	0.3	0.9	0.6	0.5	1.0	0.2	0.3	-0.3
Tail length	8.2	24.8	26.3	-5.1	-5.1	-4.9	-4.7	-5.0	5.0
Length with tail	1.9	6.9	10.1	-2.6	-1.8	-1.7	-3.2	-3.0	3.0
Length without tail	2.1	4.6	9.3	2.2	3.0	3.1	0.9	1.4	-1.4
Liver weight, left	0.6	1.0	2.1	1.0	1.5	1.4	0.4	0.6	-0.6
Liver weight, right	1.3	2.2	3.2	-1.4	-0.8	-0.9	-1.8	-1.8	1.8
Parametrial fat weight	1.8	3.5	4.3	-1.8	-1.7	-1.5	-1.9	-2.1	2.1
Retroperitoneal fat weight	4.3	14.3	16.0	-4.0	-3.4	-3.5	-3.9	-4.0	4.0
Intraocular pressure	1.3	1.9	2.4	-1.3	-1.6	-1.4	-1.3	-1.4	1.4
Extensor digitorum longus weight	0.3	1.1	2.2	-1.1	-1.5	-1.5	-0.3	-0.7	0.7
Soleus weight	1.5	4.4	4.9	-2.2	-2.0	-2.0	-2.1	-2.2	2.2
Tibialis anterior weight	0.2	0.6	1.3	-0.8	-1.0	-1.1	-0.4	-0.6	0.6
Tibia length	5.8	16.2	30.1	-3.6	-1.4	-1.6	-5.5	-5.0	5.0
Number of licking bursts	0.3	0.3	0.6	-0.6	-0.8	-0.8	-0.3	-0.4	0.4
Food consumed during 24 hour testing period	0.5	0.6	0.8	-0.8	-0.9	-0.9	-0.6	-0.7	0.7
Times rat made contact with spout	0.6	0.7	1.2	-0.8	-0.5	-0.6	-1.1	-0.9	0.9
Mean time between licks in bursts	1.2	1.7	2.6	1.3	0.8	1.0	1.6	1.5	-1.5
Mean num. licks in bursts	0.1	0.1	0.2	-0.1	0.2	0.2	-0.4	-0.3	0.3
Std. dev. time between licks in bursts	1.9	2.2	4.8	-1.6	-2.2	-2.0	-0.6	-1.0	1.0
Water consumed over 24 hours	0.2	0.2	0.4	0.5	0.6	0.6	0.2	0.3	-0.3
Indifference point 0 sec	0.0	0.1	0.2	-0.3	-0.5	-0.3	-0.1	-0.1	0.1
Indifference point AUC	0.1	0.2	0.4	-0.3	-0.7	-0.4	-0.3	-0.3	0.3
Indifference point function ln k	1.0	1.4	1.7	1.2	1.1	1.1	1.3	1.2	-1.2
Indifference point function log k	1.0	1.4	1.7	1.2	1.1	1.1	1.3	1.2	-1.2
Delay discounting total patch changes 0 sec	0.1	0.1	0.3	-0.4	-0.6	-0.3	-0.1	-0.2	0.2
Delay discounting total patch changes 12 sec	0.0	0.0	0.1	-0.2	-0.4	-0.1	-0.2	-0.1	0.1
Delay discounting total patch changes 18 sec	0.1	0.2	0.5	-0.2	-0.7	-0.5	0.2	0.1	-0.1
Delay discounting total patch changes 24 sec	0.4	0.5	0.7	-0.8	-0.8	-0.7	-0.6	-0.6	0.6
Delay discounting total patch changes 6 sec	0.2	0.3	0.4	-0.6	-0.6	-0.4	-0.7	-0.6	0.6
Delay discounting time to switch 0 sec	0.5	0.7	0.9	0.8	0.7	0.6	0.9	0.9	-0.9
Delay discounting water rate 0 sec	2.6	4.2	4.7	-2.1	-1.9	-1.8	-2.1	-2.2	2.2
Delay discounting water rate 12 sec	0.3	0.5	0.7	-0.7	-0.6	-0.6	-0.7	-0.8	0.8
Delay discounting water rate 18 sec	0.9	1.2	1.3	-1.1	-1.1	-1.1	-0.8	-1.1	1.1
Delay discounting water rate 24 sec	2.5	3.5	3.8	-1.9	-1.8	-1.9	-1.6	-1.9	1.9
Delay discounting water rate 6 sec	0.1	0.1	0.2	-0.2	-0.2	-0.1	-0.4	-0.5	0.5
Locomotor activity	1.0	1.5	1.8	1.1	1.2	1.0	1.3	1.4	-1.4
Locomotor testing distance	1.2	1.9	3.0	1.2	1.1	0.8	1.7	1.6	-1.6
Locomotor testing rearing	0.3	0.4	0.9	0.4	0.2	-0.0	0.9	0.8	-0.8
Light reinforcement 1	1.4	2.6	4.3	-1.9	-1.7	-2.1	-1.2	-1.3	1.3
Light reinforcement 2	2.0	2.6	3.4	-1.8	-1.3	-1.7	-1.6	-1.6	1.6
Reaction time number correct	1.3	1.9	4.3	-1.4	-2.1	-2.1	-0.1	-0.7	0.7
Reaction time mean minus median	0.3	0.4	0.9	0.7	1.0	0.7	0.4	0.5	-0.5
Reaction time mean minus median AUC	0.0	0.1	0.3	0.2	0.5	0.2	0.0	0.0	-0.0
Reaction time num false alarms	0.2	0.2	0.4	0.5	0.2	0.4	0.6	0.6	-0.6
Reaction time num false alarms AUC	0.4	0.6	0.9	0.8	0.4	0.5	1.0	0.9	-0.9
Reaction time trials correct on left	1.3	1.9	4.3	-1.4	-2.1	-2.1	-0.1	-0.7	0.7
Reaction time trials on left	1.4	2.0	4.5	-1.4	-2.1	-2.1	-0.1	-0.7	0.7
Reaction time mean	0.2	0.3	0.4	-0.6	-0.5	-0.6	-0.5	-0.6	0.6
Reaction time mean AUC	0.3	0.4	0.6	-0.7	-0.6	-0.8	-0.4	-0.5	0.5
Median of all reaction times	0.4	0.5	0.5	-0.7	-0.7	-0.7	-0.6	-0.7	0.7
Reaction time omissions	0.1	0.2	0.5	-0.5	-0.6	-0.7	0.1	-0.1	0.1
Reaction time false alarm rate	1.1	1.5	2.1	1.3	1.3	1.5	0.9	1.2	-1.2
Reaction time premature initiation rate	1.0	1.3	1.9	1.1	0.6	0.9	1.4	1.4	-1.4
Reaction time premature initiations	0.4	0.5	1.3	0.2	-0.6	-0.4	1.1	0.8	-0.8
Std. dev. reaction times	0.3	0.3	0.5	0.6	0.5	0.4	0.7	0.7	-0.7
Reaction time trials completed	1.4	2.0	4.5	-1.4	-2.1	-2.1	-0.1	-0.7	0.7
Reaction time trials AUC	1.4	2.0	4.6	-1.4	-2.1	-2.1	-0.1	-0.7	0.7
Social response proportion	0.2	0.3	0.4	0.6	0.3	0.5	0.7	0.5	-0.5
Social responses	0.2	0.2	0.4	0.5	0.3	0.4	0.6	0.5	-0.5
Social time	0.1	0.1	0.2	0.3	0.5	0.3	0.5	0.4	-0.4
Conditioned locomotion	5.8	6.8	7.6	-2.7	-2.7	-2.6	-2.4	-2.6	2.6
Cocaine response after cond. corrected	0.2	0.2	0.4	0.5	0.6	0.6	0.1	0.2	-0.2
Cocaine response after cond. not corrected	0.5	0.6	0.8	0.9	0.9	0.9	0.5	0.6	-0.6
Cocaine response before conditioning	0.5	0.6	1.2	0.7	0.3	0.4	1.1	0.9	-0.9
Saline control response	3.2	4.3	5.0	-2.1	-1.7	-1.9	-2.2	-2.2	2.2
Condit. Reinf. active minus inactive responses	1.1	1.4	1.9	-1.1	-0.9	-0.9	-1.3	-1.4	1.4
Condit. Reinf. active-inactive response ratio	2.0	2.1	3.4	-1.4	-0.8	-0.8	-1.8	-1.8	1.8
Condit. Reinf. active responses	0.5	0.6	0.8	-0.8	-0.7	-0.7	-0.8	-0.9	0.9
Condit. Reinf. inactive responses	0.2	0.2	0.4	0.5	0.2	0.3	0.7	0.6	-0.6
Condit. Reinf. lever presses	0.4	0.6	0.9	-0.8	-0.9	-0.9	-0.5	-0.7	0.7
Condit. Reinf. lever reinforcers received	0.5	0.7	0.8	-0.8	-0.9	-0.8	-0.8	-0.9	0.9
Pavlov. Cond. lever latency	1.0	1.4	2.3	1.3	1.3	1.5	0.8	1.0	-1.0
Pavlov. Cond. magazine entry latency	0.8	0.9	2.0	0.7	0.3	0.1	1.4	1.2	-1.2
Pavlov. Cond. change in total contacts	0.1	0.1	0.2	-0.1	-0.3	-0.5	0.4	0.3	-0.3
Pavlov. Cond. index score	0.1	0.1	0.4	-0.2	-0.4	-0.6	0.3	0.2	-0.2
Pavlov. Cond. latency score	0.2	0.2	0.6	-0.4	-0.6	-0.8	0.3	0.1	-0.1
Pavlov. Cond. lever contacts	1.6	2.2	3.6	-1.6	-1.6	-1.9	-1.0	-1.3	1.3
Pavlov. Cond. magazine entry number	0.6	0.7	1.6	-0.5	-0.1	0.1	-1.3	-1.1	1.1
Pavlov. Cond. intertrial magazine entries	2.3	2.9	3.7	-1.6	-1.5	-1.3	-1.9	-1.9	1.9
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	-0.1	-0.3	-0.5	0.5	0.3	-0.3
Pavlov. Cond. response bias	0.4	0.5	1.2	-0.8	-0.8	-1.1	-0.2	-0.4	0.4
Conditioned reinforcement - actives	0.2	0.2	0.5	-0.4	-0.7	-0.6	-0.1	-0.3	0.3
Conditioned reinforcement - inactives	1.0	1.2	1.9	-1.1	-0.9	-0.7	-1.4	-1.2	1.2
Conditioned locomotion	0.1	0.1	0.2	-0.3	-0.5	-0.4	-0.1	-0.3	0.3
Intermittent access intake day 1-15 change	1.2	1.2	1.3	-1.1	-1.1	-1.0	-1.1	-1.1	1.1
Intermittent access intake escalation	1.2	1.2	1.7	-1.1	-1.3	-1.2	-0.9	-1.0	1.0
Intermittent access intake escalation 2	0.9	0.9	1.6	-1.0	-0.4	-0.6	-1.3	-1.1	1.1
Intermitt. access day 1 inactive lever presses	0.5	0.6	1.1	-0.8	-0.4	-0.5	-1.1	-0.8	0.8
Intermitt. access day 15 inactive lever presses	1.2	1.3	1.6	-1.3	-1.2	-1.3	-1.0	-1.0	1.0
Intermitt. access escalation Index	2.0	1.8	2.9	-1.4	-1.7	-1.7	-0.9	-1.1	1.1
Intermittent access day 1 total infusions	0.5	0.6	0.9	-0.8	-1.0	-0.7	-0.8	-0.7	0.7
Intermittent access day 15 total infusions	1.4	1.5	2.4	-1.2	-1.6	-1.3	-1.0	-1.1	1.1
Intermittent access terminal intake (last 3 days)	1.7	1.8	2.2	-1.4	-1.5	-1.3	-1.3	-1.3	1.3
Intermittent access total infusions	1.1	1.2	1.8	-1.1	-1.4	-1.1	-1.0	-1.0	1.0
Intermittent access day 1 locomotion	0.6	0.6	0.9	-0.7	-0.9	-0.7	-0.7	-0.8	0.8
Intermittent access day 15 total locomotion	0.6	0.6	0.9	-0.7	-0.9	-0.6	-0.8	-0.8	0.8
Intermittent access total locomotion	0.6	0.7	1.0	-0.7	-1.0	-0.6	-0.8	-0.9	0.9
Intermittent access standard deviation	1.4	1.5	2.6	1.2	1.6	1.5	0.7	1.0	-1.0
Cocaine induced anxiety	1.6	1.8	4.8	-1.0	0.4	0.1	-2.2	-1.6	1.6
Post-drug Anxiety	0.2	0.2	0.4	0.1	0.6	0.7	-0.6	-0.1	0.1
Baseline Anxiety	5.0	5.3	8.8	2.2	1.0	1.5	3.0	2.7	-2.7
Lifetime Intake	0.4	0.4	0.8	-0.6	-0.9	-0.7	-0.5	-0.5	0.5
Incentive Sensitization - Responses	0.5	0.5	0.8	-0.8	-0.9	-0.8	-0.6	-0.6	0.6
Incentive Sensitization - Breakpoint	0.4	0.4	0.6	-0.7	-0.8	-0.6	-0.5	-0.5	0.5
Progressive ratio test 1 active lever presses	1.7	1.8	2.0	-1.4	-1.4	-1.4	-1.3	-1.3	1.3
Progressive ratio test 1 breakpoint	2.2	2.3	2.4	-1.6	-1.5	-1.5	-1.5	-1.5	1.5
Progressive ratio test 1 inactive lever presses	2.9	3.1	3.5	-1.8	-1.6	-1.6	-1.8	-1.9	1.9
Progressive ratio test 2 active lever presses	0.7	0.8	1.0	-0.9	-1.0	-0.8	-0.8	-0.8	0.8
Progressive ratio test 2 breakpoint	1.1	1.2	1.7	-1.1	-1.3	-1.1	-0.9	-1.0	1.0
Progressive ratio test 2 inactive lever presses	0.3	0.3	0.5	-0.6	-0.5	-0.4	-0.7	-0.6	0.6
Total sessions with >9 infusions	0.1	0.1	0.3	0.3	-0.2	0.2	0.5	0.4	-0.4
Short access day 1 total inactive lever presses	0.2	0.2	0.4	-0.3	-0.7	-0.7	0.2	-0.0	0.0
Short access day 10 total inactive lever presses	2.7	2.9	4.5	-1.8	-1.1	-1.3	-2.1	-1.9	1.9
Short access day 1 total infusions	1.8	2.0	2.3	1.5	1.1	1.3	1.5	1.5	-1.5
Short access day 10 total infusions	0.7	0.8	1.0	-0.8	-0.9	-0.7	-1.0	-1.0	1.0
Short access total infusions	0.0	0.0	0.1	-0.1	-0.3	-0.1	-0.1	-0.0	0.0
Short access day 1 locomotion	0.8	0.9	1.3	1.0	0.9	1.1	0.8	0.8	-0.8
Short access day 10 total locomotion	0.4	0.5	1.0	0.7	0.8	1.0	0.4	0.5	-0.5
Short access total locomotion	0.6	0.6	1.0	0.9	0.7	1.0	0.6	0.7	-0.7
Compulsive drug intake	0.4	0.4	0.6	-0.7	-0.3	-0.5	-0.7	-0.8	0.8
One hour access (0.3 mA shock)	2.4	2.8	3.0	-1.7	-1.7	-1.7	-1.6	-1.6	1.6
One hour access (shock baseline)	0.6	0.7	1.6	-0.9	-1.2	-1.1	-0.5	-0.6	0.6
Number of responses in last shaping day	0.5	0.5	0.7	-0.7	-0.8	-0.5	-0.7	-0.7	0.7
Context. condit. distance diff. score	1.6	2.0	4.0	-1.5	-2.0	-1.9	-0.7	-1.0	1.0
Locomotion velocity, session 1	3.4	3.7	4.7	2.1	2.0	2.2	1.5	1.8	-1.8
Locomotion distance, session 1	1.6	2.1	3.7	1.4	0.6	0.9	1.9	1.7	-1.7
Locomotion velocity, session 2	4.9	5.7	6.4	2.5	2.1	2.2	2.5	2.5	-2.5
Locomotion distance, session 2	0.1	0.2	0.4	0.2	-0.4	-0.1	0.7	0.4	-0.4
Locomotion velocity, session 3	2.9	3.4	3.9	2.0	1.8	2.0	1.7	1.8	-1.8
Locomotion distance, session 3	3.8	4.1	4.6	2.1	1.6	1.9	2.1	2.1	-2.1
Stereotopy head waving bouts, day 3	1.0	1.2	1.5	1.1	1.2	1.2	0.9	1.0	-1.0
Stereotopy head waving duration, day 3	0.5	0.6	0.7	0.8	0.8	0.8	0.7	0.7	-0.7
Locomotion velocity, session 7	0.7	0.8	1.3	0.8	0.5	0.6	1.1	1.1	-1.1
Locomotion distance, session 7	1.5	1.9	3.9	1.2	0.3	0.4	2.0	1.7	-1.7
Stereotopy head waving bouts, day 7	0.1	0.1	0.1	-0.3	-0.2	-0.2	-0.3	-0.3	0.3
Stereotopy head waving duration, day 7	0.2	0.2	0.3	-0.4	-0.2	-0.2	-0.5	-0.5	0.5
Locomotion velocity, session 8	0.1	0.1	0.3	0.1	-0.4	-0.2	0.5	0.3	-0.3
Locomotion distance, session 8	1.3	2.0	5.3	-1.3	-2.3	-1.9	-0.2	-0.7	0.7
Degree of sensitization distance	1.6	1.6	2.6	-1.3	-1.4	-1.6	-0.9	-1.0	1.0
Degree of sensitization stereotypy	0.3	0.3	0.4	-0.6	-0.5	-0.5	-0.6	-0.6	0.6
Condit. Reinf. active minus inactive responses	2.7	3.1	3.6	-1.8	-1.6	-1.5	-1.8	-1.9	1.9
Condit. Reinf. active-inactive response ratio	0.9	0.9	1.2	-1.0	-0.7	-0.7	-1.1	-1.1	1.1
Condit. Reinf. active responses	5.4	6.5	7.2	-2.6	-2.4	-2.3	-2.6	-2.7	2.7
Condit. Reinf. inactive responses	1.9	2.2	2.6	-1.5	-1.6	-1.5	-1.4	-1.5	1.5
Incentive salience index mean	2.3	2.8	3.0	-1.7	-1.7	-1.6	-1.6	-1.7	1.7
Condit. Reinf. lever presses	0.2	0.2	0.6	-0.4	-0.8	-0.7	0.1	-0.1	0.1
Time in familiar zone, hab. session 1	0.1	0.1	0.3	0.3	0.5	0.5	-0.1	0.0	-0.0
Time in novel zone, hab. session 1	0.0	0.0	0.1	-0.2	-0.3	-0.3	0.0	-0.1	0.1
Total zone transitions, hab. session 1	0.2	0.2	0.4	0.5	0.3	0.4	0.6	0.5	-0.5
Total locomotion distance, hab. session 1	0.1	0.2	0.3	-0.4	-0.6	-0.5	-0.2	-0.3	0.3
Locomotion velocity, hab. session 1	0.1	0.2	0.4	-0.5	-0.7	-0.6	-0.2	-0.3	0.3
Time in familiar zone, hab. session 2	0.1	0.1	0.3	0.3	-0.1	0.0	0.6	0.4	-0.4
Time in novel zone, hab. session 2	0.0	0.0	0.1	0.2	0.4	0.3	0.1	0.1	-0.1
Total zone transitions, hab. session 2	0.3	0.3	1.1	-0.4	-1.1	-0.8	0.3	-0.0	0.0
Total locomotion distance, hab. session 2	1.4	1.8	3.5	-1.4	-1.9	-1.8	-0.6	-1.0	1.0
Locomotion velocity, hab. session 2	1.7	2.3	3.9	-1.6	-2.0	-1.9	-0.8	-1.2	1.2
Novel to familiar place preference ratio	1.5	1.6	3.3	-1.0	-0.2	-0.3	-1.8	-1.6	1.6
Novelty place preference	1.4	1.5	3.2	-0.9	-0.1	-0.2	-1.8	-1.5	1.5
Time in novel zone, NPP test	1.2	1.3	2.7	-0.9	-0.1	-0.2	-1.7	-1.4	1.4
Total zone transitions, NPP test	0.4	0.6	1.6	-0.3	-1.2	-1.0	0.7	0.3	-0.3
Total locomotion distance, NPP test	1.0	1.4	3.6	-1.2	-1.9	-1.8	-0.0	-0.5	0.5
Locomotion velocity, NPP test	0.9	1.3	3.1	-1.2	-1.8	-1.6	-0.2	-0.6	0.6
Pavlov. Cond. lever latency	0.2	0.3	0.8	0.2	-0.4	-0.3	0.9	0.6	-0.6
Pavlov. Cond. magazine entry latency	1.1	1.4	3.1	-0.9	-0.3	-0.2	-1.8	-1.5	1.5
Pavlov. Cond. change in total contacts	0.3	0.3	0.8	0.4	0.8	0.9	-0.3	-0.0	0.0
Pavlov. Cond. index score	1.6	2.1	3.8	-1.3	-0.7	-0.7	-1.9	-1.7	1.7
Pavlov. Cond. latency score	1.0	1.3	2.8	-1.0	-0.3	-0.4	-1.7	-1.4	1.4
Pavlov. Cond. lever contacts	0.2	0.2	0.6	-0.4	-0.1	-0.1	-0.8	-0.6	0.6
Pavlov. Cond. magazine entry number	0.8	0.9	2.5	0.5	-0.2	-0.3	1.6	1.2	-1.2
Pavlov. Cond. intertrial magazine entries	0.9	1.1	1.8	-1.1	-1.3	-1.3	-0.6	-0.9	0.9
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.1	3.9	-1.3	-0.6	-0.6	-2.0	-1.7	1.7
Pavlov. Cond. response bias	0.7	0.9	2.3	-0.6	0.1	0.1	-1.5	-1.2	1.2
Bone: apparent density	0.2	0.4	0.5	-0.7	-0.7	-0.7	-0.4	-0.6	0.6
Bone surface	0.3	0.5	0.6	-0.7	-0.7	-0.7	-0.6	-0.6	0.6
Bone volume	0.4	0.6	0.7	-0.8	-0.8	-0.8	-0.6	-0.8	0.8
Bone: connectivity density	0.2	0.3	0.8	-0.5	-0.9	-0.8	0.1	-0.1	0.1
Bone: cortical apparent density	3.0	3.9	4.4	2.1	1.7	1.8	2.0	2.1	-2.1
Bone: cortical area	3.8	5.7	9.7	-2.1	-1.1	-0.7	-3.1	-3.0	3.0
Bone: cortical porosity	0.7	0.7	1.9	0.3	1.4	1.1	-0.8	-0.4	0.4
Bone: cortical porosity	0.5	0.5	1.1	-0.0	0.9	0.7	-1.0	-0.6	0.6
Bone: cortical thickness	2.5	4.1	8.6	-1.4	-0.1	0.2	-2.9	-2.6	2.6
Bone: cortical thickness	0.8	0.9	1.8	-0.6	0.2	0.3	-1.3	-1.2	1.2
Bone: cortical tissue density	3.4	4.4	5.1	2.2	1.8	1.9	2.2	2.3	-2.3
Bone: elastic displacement	0.7	0.8	1.5	-0.8	-0.2	-0.3	-1.2	-1.1	1.1
Bone: elastic work	3.7	4.8	10.0	-1.7	-0.3	-0.3	-3.2	-2.8	2.8
Bone: endosteal estimation	0.3	0.5	1.2	-0.7	-1.1	-1.1	-0.1	-0.4	0.4
Bone: endosteal perimeter	0.6	1.3	1.5	-1.2	-1.0	-1.1	-1.2	-1.2	1.2
Bone: final force	4.0	6.5	10.5	-2.3	-1.2	-1.0	-3.2	-3.2	3.2
Bone: final moment	4.4	7.2	11.7	-2.4	-1.2	-1.0	-3.4	-3.4	3.4
Bone: marrow area	0.2	0.5	1.1	-0.6	-1.1	-1.1	-0.1	-0.4	0.4
Bone: maximum diameter	0.9	1.7	2.6	-1.3	-0.8	-0.7	-1.6	-1.6	1.6
Bone: maximum force	4.4	7.7	12.0	-2.5	-1.4	-1.3	-3.4	-3.5	3.5
Bone: maximum moment	4.8	8.4	13.3	-2.7	-1.4	-1.4	-3.6	-3.6	3.6
Bone: minimum diameter	2.1	3.9	5.8	-1.9	-1.3	-1.1	-2.4	-2.4	2.4
Bone: periosteal estimation	1.7	3.4	4.9	-1.8	-1.4	-1.2	-2.1	-2.2	2.2
Bone: periosteal perimeter	1.7	2.8	5.3	-1.4	-0.4	-0.3	-2.3	-2.1	2.1
Bone: post-yield work	0.1	0.1	0.2	-0.3	-0.5	-0.4	-0.0	-0.2	0.2
Bone: stiffness	0.6	1.0	1.9	-0.7	-0.2	-0.1	-1.3	-1.4	1.4
Bone: tissue strength	1.6	1.5	1.9	-1.2	-1.2	-1.0	-1.2	-1.4	1.4
Bone: trabecular number	0.0	0.1	0.1	-0.2	-0.4	-0.3	-0.1	-0.1	0.1
Bone: trabecular spacing	1.0	1.2	2.6	-1.2	-1.6	-1.6	-0.3	-0.7	0.7
Bone: trabecular thickness	0.3	0.4	0.6	0.1	0.8	0.7	-0.7	-0.5	0.5
Bone: trabecular tissue density	0.8	1.1	1.2	1.1	1.0	0.9	1.1	1.1	-1.1
Breakpoint value in progressive ratio session	0.2	0.2	0.7	0.1	0.8	0.6	-0.5	-0.2	0.2
Distance traveled before self-admin	0.3	0.3	0.8	-0.5	0.3	0.1	-0.9	-0.6	0.6
Distance traveled after self-admin	1.1	1.2	2.2	-1.2	-1.4	-1.5	-0.7	-0.8	0.8
Delta time in closed arm before/after self-admin	0.1	0.1	0.2	-0.1	-0.4	-0.3	0.2	0.1	-0.1
Delta time in open arm before/after self-admin	0.0	0.0	0.0	-0.0	0.1	-0.1	0.2	0.2	-0.2
Diff in mean of infusions in LGA sessions	0.6	0.7	1.8	0.7	1.3	0.6	0.6	0.6	-0.6
Extinction: sum of active levers before priming	3.2	3.2	5.0	1.9	2.2	2.0	1.4	1.6	-1.6
Active lever presses in extinction session 6	2.1	2.0	3.7	1.5	1.8	1.9	0.8	1.1	-1.1
Delta distance traveled before/after self-admin	0.3	0.3	0.8	-0.2	-0.9	-0.9	0.5	0.2	-0.2
Delta ambulatory time before/after self-admin	0.4	0.4	1.0	0.2	-0.6	-0.5	1.0	0.7	-0.7
Time in closed arm before self-admin	0.4	0.4	0.9	0.6	1.0	1.0	0.2	0.3	-0.3
Time in closed arm after self-admin	1.2	1.3	2.2	1.2	1.4	1.5	0.7	0.9	-0.9
Time in open arm before self-admin	0.1	0.1	0.2	0.1	-0.3	-0.2	0.4	0.2	-0.2
Time in open arm after self-admin	0.1	0.1	0.2	0.1	-0.1	-0.1	0.5	0.4	-0.4
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.7	-0.3	0.1	0.1	-0.8	-0.6	0.6
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.3	-0.4	-0.5	-0.5	-0.3	-0.4	0.4
Time to tail flick, vehicle, after self-admin	2.0	2.2	2.7	1.5	1.4	1.3	1.6	1.5	-1.5
Time to tail flick, test, before self-admin	0.2	0.2	0.3	-0.3	-0.5	-0.3	-0.5	-0.4	0.4
Time to tail flick, test, after self-admin	0.5	0.5	0.7	0.8	0.5	0.7	0.7	0.8	-0.8
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.4	0.3	0.1	-0.0	0.7	0.5	-0.5
Delta time to tail flick, test, before/after SA	1.7	1.5	2.1	1.3	1.3	1.4	1.0	1.1	-1.1
Ambulatory time before self-admin	0.8	0.9	1.9	-0.9	-0.1	-0.3	-1.4	-1.1	1.1
Ambulatory time after self-admin	0.4	0.5	0.8	-0.8	-0.9	-0.9	-0.5	-0.5	0.5
Total heroin consumption	1.1	1.3	3.3	1.0	1.8	1.6	0.4	0.5	-0.5
Area under the delay curve	1.5	1.6	2.0	1.3	1.0	1.1	1.4	1.3	-1.3
Delay disc. indifference point, 0s delay	0.2	0.2	0.2	0.4	0.5	0.5	0.4	0.3	-0.3
Delay disc. indifference point, 16s delay	0.9	0.9	2.0	0.8	0.1	0.2	1.4	1.1	-1.1
Delay disc. indifference point, 2s delay	0.5	0.6	0.6	0.8	0.7	0.8	0.8	0.7	-0.7
Delay disc. indifference point, 24s delay	6.2	6.0	6.8	2.6	2.2	2.4	2.4	2.6	-2.6
Delay disc. indifference point, 4s delay	0.5	0.5	0.8	0.7	0.9	0.7	0.7	0.6	-0.6
Delay disc. indifference point, 8s delay	1.2	1.2	1.5	1.2	1.2	1.2	0.9	1.1	-1.1
Delay discount exponential model param	2.2	2.4	2.6	-1.6	-1.4	-1.4	-1.6	-1.6	1.6
Delay discount hyperbolic model param	2.2	2.3	2.6	-1.6	-1.4	-1.4	-1.6	-1.6	1.6
Fecal boli incidents, locomotor time 1	0.3	0.3	0.5	0.6	0.2	0.3	0.7	0.7	-0.7
Change in fecal boli incidents, locomotor task	3.0	2.8	3.6	1.7	1.9	1.8	1.4	1.6	-1.6
Time >=10cm from walls, locomotor time 1	2.0	2.0	3.7	-1.5	-1.9	-1.8	-0.8	-1.0	1.0
Bouts of movement, locomotor time 1	1.9	2.2	2.7	1.5	1.6	1.3	1.4	1.5	-1.5
Total resting periods, locomotor time 1	2.5	2.7	3.3	1.7	1.8	1.6	1.5	1.6	-1.6
Rest time, locomotor task time 1	0.4	0.5	0.7	0.7	0.9	0.8	0.5	0.6	-0.6
Distance moved, locomotor task time 1	0.7	0.7	0.8	-0.9	-0.8	-0.9	-0.7	-0.9	0.9
Vertical activity count, locomotor time 1	1.3	1.4	1.9	-1.3	-1.1	-1.4	-0.9	-1.1	1.1
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.3	-0.3	-0.5	-0.2	-0.2	-0.2	0.2
Bouts of movement, locomotor time 2	0.8	0.8	1.0	0.9	0.8	0.6	1.0	1.0	-1.0
Total resting periods, locomotor time 2	0.3	0.3	0.6	0.6	0.3	0.2	0.7	0.7	-0.7
Rest time, locomotor task time 2	0.0	0.0	0.0	0.0	0.2	-0.2	0.1	0.0	-0.0
Distance moved, locomotor task time 2	0.0	0.0	0.0	0.1	0.1	0.2	0.0	-0.0	0.0
Vertical activity count, locomotor time 2	0.1	0.1	0.2	-0.4	-0.5	-0.4	-0.1	-0.3	0.3
Weight adjusted by age	1.2	1.4	2.3	-1.2	-0.6	-0.7	-1.5	-1.4	1.4
Seeking ratio, delayed vs. immediate footshock	1.7	1.9	2.2	-1.5	-1.2	-1.3	-1.4	-1.4	1.4
Locomotion in novel chamber	0.2	0.3	0.5	0.4	0.1	0.1	0.7	0.7	-0.7
Locomotion in novel chamber post-restriction	3.3	3.9	4.3	-2.0	-1.9	-1.7	-2.1	-2.0	2.0
Progressive ratio	0.5	0.6	0.7	0.8	0.6	0.7	0.8	0.8	-0.8
Food seeking constrained by brief footshock	0.3	0.4	0.5	0.7	0.7	0.7	0.4	0.5	-0.5
Seeking ratio, punishment vs. effort	0.2	0.3	0.4	-0.6	-0.6	-0.6	-0.5	-0.5	0.5
Run reversals in cocaine runway, females	0.4	0.3	0.8	0.2	-0.2	-0.2	0.9	0.8	-0.8
Run reversals in cocaine runway, males	0.5	0.5	1.1	-0.6	-0.1	-0.1	-1.1	-0.8	0.8
Latency to leave start box in cocaine runway	0.0	0.1	0.2	0.1	-0.1	-0.2	0.4	0.2	-0.2
Latency to leave start box in cocaine runway, F	0.1	0.1	0.3	-0.1	-0.3	-0.5	0.5	0.3	-0.3
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	-0.3	-0.3	-0.2	-0.5	-0.4	0.4
Cd content in liver	1.3	1.5	2.0	1.3	0.8	1.1	1.4	1.3	-1.3
Co content in liver	0.1	0.2	0.4	0.3	-0.0	0.1	0.6	0.5	-0.5
Cu content in liver	0.2	0.2	0.5	0.2	0.5	0.7	-0.5	-0.2	0.2
Fe content in liver	0.9	1.0	1.8	0.9	0.5	0.5	1.3	1.2	-1.2
K content in liver	3.2	3.2	4.8	-1.9	-2.2	-2.0	-1.4	-1.5	1.5
Mg content in liver	1.6	1.6	3.9	-1.3	-2.0	-1.8	-0.3	-0.6	0.6
Mn content in liver	0.1	0.2	0.3	-0.4	-0.3	-0.2	-0.5	-0.5	0.5
Na content in liver	0.0	0.0	0.1	0.0	0.1	-0.0	0.2	0.3	-0.3
Rb content in liver	1.5	1.9	2.6	-1.5	-1.6	-1.5	-1.2	-1.2	1.2
Se content in liver	0.6	0.7	1.2	-0.9	-1.0	-1.1	-0.6	-0.7	0.7
Sr content in liver	1.0	0.9	1.8	1.0	1.3	1.3	0.3	0.6	-0.6
Zn content in liver	0.0	0.0	0.0	0.1	-0.2	0.1	0.0	0.1	-0.1