Hub : Genes

Phospho1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000007352 0.13 0.09 5.9e-04 0.01 0.01 0.01 0.01 6.9e-03 1.5e-02 2.6e-02 2.5e-02
2 Adipose alternative polyA ENSRNOT00000104900 0.12 0.09 6.3e-04 0.01 0.01 0.01 0.01 1.1e-02 1.5e-02 3.4e-02 3.2e-02
3 Adipose alternative polyA ENSRNOT00000007352 0.28 0.14 1.9e-09 0.07 0.06 0.08 0.06 4.4e-08 2.8e-07 8.8e-09 9.7e-08
4 Adipose alternative polyA ENSRNOT00000104900 0.27 0.14 2.7e-09 0.07 0.06 0.07 0.06 6.3e-08 3.9e-07 1.3e-08 1.6e-07
5 Adipose alternative TSS ENSRNOT00000007352 0.03 0.03 6.7e-03 0.02 0.01 0.01 0.01 5.2e-03 1.4e-02 2.6e-02 1.2e-02
6 Adipose alternative TSS ENSRNOT00000115688 0.08 0.06 3.4e-03 0 0.01 0.01 0 1.7e-01 3.0e-02 1.3e-02 1.4e-01
7 Adipose gene expression ENSRNOG00000005569 0.34 0.12 0.0e+00 0.31 0.29 0.3 0.3 3.4e-35 2.3e-32 1.8e-33 2.7e-34
8 Adipose isoform ratio ENSRNOT00000115688 0.02 0.02 4.1e-03 0.01 0.01 0.01 0.01 7.4e-03 3.4e-02 1.5e-02 1.2e-02
9 BLA isoform ratio ENSRNOT00000094757 0.05 0.04 7.6e-03 0.04 0.02 0.02 0.03 3.7e-03 1.8e-02 3.1e-02 1.4e-02
10 Brain alternative polyA ENSRNOT00000007352 0.02 0.02 9.9e-03 0.01 0.02 0 0.01 3.8e-02 1.2e-02 1.6e-01 3.9e-02
11 Brain alternative polyA ENSRNOT00000104900 0.02 0.02 8.3e-03 0.02 0.02 0.01 0.01 1.1e-02 1.0e-02 6.5e-02 1.5e-02
12 Brain gene expression ENSRNOG00000005569 0.09 0.06 2.6e-09 0.07 0.1 0.09 0.09 2.8e-07 9.5e-10 5.4e-09 7.8e-09
13 Eye gene expression ENSRNOG00000005569 0.31 0.17 2.9e-03 0.06 0.04 0.02 0.02 4.8e-02 8.0e-02 1.6e-01 1.8e-01
14 Liver alternative polyA ENSRNOT00000007352 0.11 0.06 0.0e+00 0.14 0.15 0.15 0.15 2.3e-15 2.6e-16 1.4e-16 1.9e-16
15 Liver alternative polyA ENSRNOT00000104900 0.12 0.07 0.0e+00 0.16 0.15 0.15 0.15 3.4e-17 2.1e-16 1.7e-16 2.6e-16
16 Liver alternative polyA ENSRNOT00000007352 0.31 0.1 0.0e+00 0.43 0.43 0.44 0.44 5.2e-52 2.2e-52 1.6e-53 1.2e-53
17 Liver alternative polyA ENSRNOT00000104900 0.31 0.1 0.0e+00 0.43 0.43 0.44 0.44 4.7e-52 1.4e-52 9.7e-54 7.1e-54
18 Liver alternative TSS ENSRNOT00000007352 0.08 0.04 2.4e-15 0.13 0.12 0.13 0.13 2.4e-14 1.3e-13 2.8e-14 1.2e-14
19 Liver alternative TSS ENSRNOT00000094757 0.02 0.01 6.2e-03 0.01 0.01 0.01 0.01 1.7e-02 2.5e-02 2.7e-02 1.7e-02
20 Liver alternative TSS ENSRNOT00000115688 0.1 0.05 0.0e+00 0.17 0.17 0.18 0.17 8.2e-19 2.5e-18 2.0e-19 1.6e-18
21 Liver gene expression ENSRNOG00000005569 0.5 0.1 0.0e+00 0.59 0.59 0.6 0.6 6.9e-82 2.1e-80 2.1e-83 9.4e-84
22 Liver isoform ratio ENSRNOT00000115688 0.02 0.02 9.5e-03 0.01 0.02 0.01 0.01 9.7e-03 2.2e-03 6.9e-02 1.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail14.747.769.9-7.37.3-7.77.8-7.12.2-7.3-7.28.4-6.26.3-5.7-1.2-7.47.2-7.17.2-7.1-7.37.4-7.2-7.8
BMI without tail0.71.52.9-1.31.3-1.51.6-1.0-0.5-1.3-1.21.7-0.80.8-0.51.3-1.41.5-1.11.1-1.0-1.21.3-1.1-1.4
Body weight0.83.35.4-1.81.8-1.41.4-1.71.4-1.8-1.62.1-1.91.9-1.8-1.2-2.22.3-1.81.8-1.8-1.92.0-1.8-1.9
Epididymis fat weight0.00.10.7-0.10.10.2-0.2-0.0-0.4-0.1-0.10.8-0.20.2-0.10.6-0.40.4-0.20.2-0.2-0.30.3-0.2-0.3
Glucose0.91.33.2-1.01.0-0.60.6-1.11.8-1.0-1.01.2-1.41.3-1.4-1.8-1.21.2-1.01.0-1.1-1.11.1-0.9-1.0
Heart weight0.70.93.4-0.80.8-0.50.5-1.00.5-0.8-0.71.8-1.11.1-1.0-0.8-1.11.0-0.90.9-1.0-1.31.1-0.9-1.0
Left kidney weight0.10.21.80.2-0.20.6-0.6-0.00.90.20.20.2-0.30.3-0.3-1.3-0.10.20.1-0.10.00.1-0.00.10.2
Right kidney weight0.51.55.5-0.80.8-0.40.4-1.42.0-0.8-0.71.1-1.51.5-1.6-2.4-1.21.3-1.01.0-1.1-1.11.1-1.0-1.0
Tail length14.844.759.27.0-7.07.7-7.77.1-2.57.07.0-7.76.1-6.15.72.06.9-6.67.0-7.06.97.1-7.07.17.4
Length with tail7.125.944.75.4-5.46.6-6.75.4-0.15.45.5-6.04.1-4.13.7-0.75.0-4.75.3-5.35.25.4-5.35.45.9
Length without tail0.20.56.50.1-0.10.8-0.80.01.60.10.2-0.1-0.50.5-0.7-2.5-0.10.2-0.00.0-0.1-0.00.00.00.2
Liver weight, left0.81.42.31.3-1.31.5-1.51.30.11.31.4-1.21.0-1.00.90.61.0-0.81.2-1.21.21.3-1.21.31.3
Liver weight, right0.61.13.41.1-1.11.8-1.91.11.01.11.1-0.90.4-0.50.4-1.00.5-0.31.1-1.11.00.8-0.91.11.2
Parametrial fat weight0.30.62.60.6-0.60.5-0.40.7-1.20.60.7-0.20.8-0.80.91.60.7-0.80.9-0.80.70.5-0.60.80.5
Retroperitoneal fat weight0.20.51.0-0.80.8-0.70.7-0.60.2-0.8-0.70.9-0.70.7-0.7-0.3-0.70.6-0.70.7-0.8-1.00.7-0.7-0.8
Intraocular pressure1.31.82.11.4-1.41.5-1.41.4-1.21.41.3-1.51.3-1.31.21.01.3-1.31.4-1.41.31.4-1.41.41.3
Extensor digitorum longus weight0.93.66.0-1.81.8-1.61.6-1.82.3-1.8-1.81.8-2.02.0-2.0-1.5-2.32.5-1.91.9-1.8-1.92.0-1.8-1.8
Soleus weight1.54.55.9-2.22.2-1.91.9-2.12.1-2.2-2.22.2-2.22.2-2.2-1.4-2.32.4-2.22.2-2.1-2.02.2-2.2-2.1
Tibialis anterior weight0.10.22.50.2-0.2-0.40.40.3-0.20.20.2-0.60.5-0.50.51.6-0.10.40.2-0.10.30.5-0.20.20.2
Tibia length0.61.64.5-1.11.1-0.70.7-1.21.7-1.1-1.11.3-1.51.5-1.5-2.1-1.21.1-1.11.1-1.2-1.21.2-1.1-1.2
Number of licking bursts1.51.74.31.3-1.31.1-1.11.1-2.11.31.3-0.81.4-1.41.41.41.4-1.61.3-1.31.21.0-1.31.31.1
Food consumed during 24 hour testing period1.82.22.91.5-1.51.5-1.51.6-0.91.51.6-1.71.5-1.51.51.11.5-1.41.6-1.61.61.6-1.51.61.6
Times rat made contact with spout0.91.01.70.9-0.91.0-1.00.9-0.90.91.1-0.60.9-0.91.00.51.2-1.31.1-1.11.01.0-1.01.11.0
Mean time between licks in bursts0.71.03.2-0.90.9-0.40.4-1.10.8-0.9-0.81.4-1.31.2-1.3-1.8-0.60.3-1.00.9-1.1-1.10.9-1.0-0.9
Mean num. licks in bursts0.20.21.8-0.40.4-0.0-0.0-0.31.3-0.4-0.30.2-0.50.5-0.6-1.0-0.30.4-0.30.3-0.2-0.20.3-0.3-0.1
Std. dev. time between licks in bursts0.70.91.3-0.90.9-1.01.0-1.10.6-0.9-0.90.8-1.01.0-1.0-1.1-0.80.7-1.01.0-1.1-0.90.9-1.0-1.0
Water consumed over 24 hours0.10.10.20.3-0.30.3-0.30.1-0.20.30.4-0.40.2-0.20.20.10.3-0.40.3-0.30.20.1-0.30.30.2
Indifference point 0 sec1.42.33.1-1.51.5-1.61.6-1.81.2-1.5-1.60.9-1.51.5-1.6-0.9-1.61.4-1.61.6-1.6-1.71.6-1.7-1.6
Indifference point AUC0.10.10.60.2-0.20.2-0.20.10.20.20.1-0.40.1-0.10.0-0.80.1-0.20.2-0.20.10.1-0.20.30.2
Indifference point function ln k0.00.00.30.1-0.10.0-0.00.2-0.10.10.2-0.30.2-0.20.20.60.1-0.00.1-0.10.10.2-0.10.10.1
Indifference point function log k0.00.00.30.1-0.10.0-0.00.2-0.10.10.2-0.30.2-0.20.20.60.1-0.00.1-0.10.10.2-0.10.10.1
Delay discounting total patch changes 0 sec1.52.53.3-1.51.5-1.61.6-1.81.3-1.5-1.71.1-1.71.7-1.7-1.1-1.61.4-1.71.7-1.7-1.81.7-1.7-1.6
Delay discounting total patch changes 12 sec0.00.00.30.0-0.0-0.10.1-0.4-0.50.0-0.30.1-0.10.1-0.1-0.30.1-0.3-0.00.0-0.0-0.40.1-0.1-0.1
Delay discounting total patch changes 18 sec2.22.93.8-1.61.6-1.61.6-1.91.2-1.6-2.01.5-1.81.8-1.8-1.5-1.71.4-1.81.8-1.9-1.91.7-1.8-1.8
Delay discounting total patch changes 24 sec1.21.52.1-1.21.2-1.41.4-1.41.0-1.2-1.30.8-1.21.2-1.2-0.6-1.31.2-1.21.2-1.2-1.41.3-1.2-1.2
Delay discounting total patch changes 6 sec1.11.72.1-1.41.4-1.41.4-1.41.0-1.4-1.40.9-1.31.3-1.3-1.0-1.31.1-1.31.3-1.3-1.41.3-1.3-1.3
Delay discounting time to switch 0 sec0.10.20.70.5-0.50.4-0.40.3-0.80.50.3-0.30.5-0.50.50.50.4-0.40.4-0.40.40.2-0.40.30.4
Delay discounting water rate 0 sec2.03.24.5-2.02.0-2.02.0-1.71.7-2.0-1.81.6-1.81.8-1.7-1.1-2.02.1-1.71.7-1.7-1.61.9-1.7-1.8
Delay discounting water rate 12 sec0.71.02.0-1.11.1-0.90.8-0.81.4-1.1-1.00.8-1.11.1-1.1-0.3-1.11.3-1.01.0-1.0-0.71.1-1.0-1.0
Delay discounting water rate 18 sec0.00.00.2-0.10.1-0.30.3-0.10.2-0.10.00.2-0.10.1-0.00.50.00.00.1-0.10.0-0.10.10.1-0.1
Delay discounting water rate 24 sec1.31.92.6-1.41.4-1.51.4-1.41.0-1.4-1.41.6-1.31.4-1.3-0.5-1.41.4-1.31.3-1.4-1.41.5-1.3-1.5
Delay discounting water rate 6 sec0.20.31.4-0.40.4-1.01.0-0.2-0.1-0.4-0.4-0.1-0.10.1-0.01.2-0.50.7-0.40.4-0.4-0.10.4-0.3-0.5
Locomotor activity0.20.31.6-0.50.5-0.90.9-0.2-1.3-0.5-0.50.4-0.00.00.10.9-0.30.3-0.50.5-0.5-0.30.4-0.6-0.6
Locomotor testing distance0.40.62.5-0.50.5-1.21.2-0.7-1.6-0.5-0.60.5-0.10.10.01.3-0.50.4-0.70.7-0.7-0.80.6-0.7-0.9
Locomotor testing rearing0.20.32.3-0.20.2-0.91.0-0.3-1.5-0.2-0.3-0.20.3-0.20.41.3-0.40.4-0.20.2-0.2-0.40.3-0.3-0.5
Light reinforcement 10.10.10.9-0.10.1-0.60.6-0.3-0.9-0.1-0.2-0.10.2-0.10.21.0-0.1-0.0-0.20.2-0.2-0.00.1-0.2-0.3
Light reinforcement 20.50.71.70.8-0.80.6-0.60.7-1.20.80.8-0.80.9-0.90.91.30.9-0.90.7-0.70.70.7-0.80.70.7
Reaction time number correct1.21.72.5-1.21.2-0.90.9-1.41.2-1.2-1.21.2-1.61.5-1.6-0.8-1.31.1-1.41.4-1.5-1.51.4-1.4-1.4
Reaction time mean minus median1.92.53.51.7-1.71.7-1.71.6-0.31.71.6-1.51.5-1.51.4-0.21.5-1.41.8-1.81.71.6-1.61.91.9
Reaction time mean minus median AUC3.03.85.12.0-2.02.1-2.12.0-0.82.02.0-1.61.9-1.91.80.41.9-1.82.2-2.22.22.0-2.02.32.2
Reaction time num false alarms0.60.91.90.8-0.80.5-0.51.0-1.10.80.8-1.11.1-1.11.11.01.1-1.00.7-0.70.81.4-1.00.70.9
Reaction time num false alarms AUC0.70.92.00.8-0.80.5-0.51.1-1.10.80.8-1.21.1-1.11.10.91.2-1.10.7-0.80.91.4-1.00.70.9
Reaction time trials correct on left1.21.72.5-1.21.2-0.90.9-1.41.2-1.2-1.21.2-1.61.5-1.6-0.8-1.31.1-1.41.4-1.5-1.51.4-1.4-1.4
Reaction time trials on left1.11.62.3-1.21.2-0.90.9-1.31.2-1.2-1.21.1-1.51.5-1.5-0.7-1.21.1-1.41.4-1.4-1.41.3-1.4-1.3
Reaction time mean1.11.52.51.2-1.21.6-1.61.50.11.21.2-0.81.1-1.11.1-0.61.0-0.91.4-1.41.51.3-1.21.51.5
Reaction time mean AUC1.41.82.81.3-1.31.6-1.71.6-0.11.31.4-0.91.3-1.31.3-0.41.1-1.01.6-1.61.61.4-1.31.61.7
Median of all reaction times0.40.61.10.7-0.71.0-1.01.00.20.70.7-0.30.7-0.70.7-0.50.5-0.40.9-0.91.00.8-0.70.91.0
Reaction time omissions1.11.51.91.3-1.31.2-1.21.0-1.11.31.3-1.01.3-1.31.20.61.3-1.31.4-1.31.31.3-1.31.41.2
Reaction time false alarm rate1.41.93.21.2-1.20.8-0.81.5-1.61.21.2-1.51.6-1.61.61.21.6-1.51.2-1.31.41.8-1.51.21.4
Reaction time premature initiation rate0.20.30.50.7-0.70.4-0.40.4-0.40.70.5-0.70.5-0.50.50.40.6-0.70.4-0.50.40.5-0.60.40.5
Reaction time premature initiations0.00.00.10.1-0.10.0-0.0-0.20.40.1-0.1-0.3-0.20.2-0.3-0.00.0-0.1-0.20.2-0.3-0.20.0-0.3-0.2
Std. dev. reaction times1.82.53.81.6-1.61.9-1.91.8-0.11.61.6-1.41.4-1.51.4-0.61.5-1.31.8-1.81.81.8-1.61.81.9
Reaction time trials completed1.11.62.3-1.21.2-0.90.9-1.31.2-1.2-1.21.1-1.51.5-1.5-0.7-1.21.1-1.41.4-1.4-1.41.3-1.4-1.3
Reaction time trials AUC1.11.62.3-1.21.2-0.90.9-1.31.2-1.2-1.21.1-1.51.5-1.5-0.7-1.31.2-1.41.4-1.5-1.41.3-1.4-1.4
Social response proportion1.81.92.61.4-1.41.2-1.21.6-0.81.41.5-1.61.5-1.51.51.61.3-1.21.4-1.41.31.5-1.41.41.5
Social responses0.20.32.4-0.40.4-0.90.9-0.1-0.6-0.4-0.1-0.50.2-0.20.31.5-0.10.2-0.20.2-0.2-0.10.2-0.3-0.3
Social time0.50.74.7-0.40.4-1.31.4-0.4-2.2-0.4-0.40.40.4-0.30.51.90.3-0.5-0.40.3-0.4-0.30.2-0.4-0.6
Conditioned locomotion1.41.73.3-1.21.2-1.31.3-1.70.5-1.2-1.31.5-1.31.3-1.3-0.6-1.20.8-1.31.3-1.4-1.81.4-1.3-1.5
Cocaine response after cond. corrected5.25.97.9-2.62.6-2.82.8-2.60.9-2.6-2.62.8-2.22.2-2.1-0.2-2.52.4-2.52.5-2.5-2.62.6-2.5-2.7
Cocaine response after cond. not corrected3.23.55.2-2.12.1-2.32.3-2.00.4-2.1-2.12.1-1.61.6-1.50.2-1.81.7-1.91.9-1.9-1.92.0-2.0-2.1
Cocaine response before conditioning2.22.73.81.4-1.41.6-1.61.9-1.21.41.5-1.91.6-1.61.61.11.9-1.91.6-1.61.72.0-1.71.61.8
Saline control response0.30.43.80.3-0.3-0.20.2-0.4-2.00.30.20.70.3-0.30.41.10.5-0.90.1-0.2-0.0-0.5-0.10.0-0.3
Condit. Reinf. active minus inactive responses0.40.52.00.5-0.50.4-0.40.4-1.40.50.7-0.20.7-0.70.81.40.6-0.60.7-0.60.60.5-0.60.60.4
Condit. Reinf. active-inactive response ratio1.01.17.80.6-0.60.1-0.00.5-2.50.60.6-0.11.1-1.11.32.80.7-0.90.7-0.70.70.5-0.60.60.3
Condit. Reinf. active responses0.20.20.40.5-0.50.6-0.60.4-0.60.50.6-0.30.5-0.50.50.40.3-0.30.6-0.50.50.4-0.40.50.4
Condit. Reinf. inactive responses0.20.22.40.0-0.00.3-0.3-0.11.00.00.0-0.1-0.40.3-0.4-1.6-0.20.3-0.10.1-0.1-0.10.1-0.00.1
Condit. Reinf. lever presses0.30.41.10.7-0.70.8-0.80.50.60.70.7-1.10.4-0.40.3-0.40.4-0.30.7-0.70.70.7-0.70.80.8
Condit. Reinf. lever reinforcers received0.20.30.50.6-0.60.7-0.60.4-0.50.60.7-0.40.5-0.50.50.40.3-0.30.6-0.60.60.5-0.50.60.5
Pavlov. Cond. lever latency2.02.85.61.5-1.51.4-1.41.8-2.41.51.6-1.01.8-1.81.91.91.8-2.01.6-1.61.61.5-1.61.61.5
Pavlov. Cond. magazine entry latency0.50.61.90.7-0.71.0-1.10.51.30.70.7-0.90.1-0.2-0.0-1.40.6-0.50.6-0.60.50.7-0.70.60.8
Pavlov. Cond. change in total contacts0.71.03.4-0.70.7-0.70.7-1.01.8-0.7-0.90.2-1.11.1-1.2-1.7-1.01.2-0.90.9-0.9-0.70.8-0.8-0.7
Pavlov. Cond. index score0.70.94.1-0.60.6-0.50.5-0.92.0-0.6-0.70.4-1.11.1-1.2-1.9-0.91.0-0.70.8-0.8-0.60.7-0.7-0.6
Pavlov. Cond. latency score0.50.63.5-0.50.5-0.30.3-0.61.9-0.5-0.50.1-0.80.8-1.0-1.8-0.60.7-0.50.5-0.6-0.40.5-0.5-0.3
Pavlov. Cond. lever contacts1.42.04.0-1.21.2-1.31.3-1.52.0-1.2-1.40.9-1.51.5-1.6-1.6-1.51.6-1.31.4-1.3-1.31.3-1.3-1.3
Pavlov. Cond. magazine entry number0.50.65.40.0-0.0-0.50.50.3-2.10.00.00.10.7-0.70.92.30.3-0.40.1-0.20.20.0-0.10.1-0.1
Pavlov. Cond. intertrial magazine entries2.02.66.41.5-1.51.3-1.31.7-2.51.51.4-1.21.8-1.81.82.31.7-1.71.4-1.41.41.5-1.51.41.4
Pavlov. Cond. lever-magazine prob. diff.0.91.14.5-0.80.8-0.60.6-1.02.1-0.8-0.80.4-1.21.2-1.3-2.0-1.01.1-0.80.9-0.9-0.70.8-0.8-0.7
Pavlov. Cond. response bias1.01.44.1-0.90.9-0.80.8-1.32.0-0.9-1.00.7-1.31.3-1.4-1.9-1.21.3-1.11.1-1.1-1.01.0-1.0-1.0
Conditioned reinforcement - actives0.50.51.30.8-0.80.7-0.70.5-1.20.80.70.00.6-0.70.80.80.5-0.50.7-0.70.60.5-0.60.70.4
Conditioned reinforcement - inactives0.30.41.80.6-0.60.9-0.80.3-1.40.60.50.10.4-0.50.50.50.6-0.70.5-0.50.40.2-0.40.50.3
Conditioned locomotion0.10.11.4-0.00.0-0.30.4-0.5-1.2-0.00.10.6-0.00.00.10.4-0.0-0.10.00.0-0.2-0.40.0-0.0-0.4
Intermittent access intake day 1-15 change0.70.71.1-0.70.7-0.91.0-1.00.3-0.7-0.90.7-0.70.8-0.70.1-1.00.9-1.01.0-1.0-0.90.9-1.0-1.0
Intermittent access intake escalation0.30.30.5-0.40.4-0.60.7-0.70.3-0.4-0.60.3-0.50.5-0.50.1-0.70.6-0.70.7-0.7-0.60.7-0.7-0.7
Intermittent access intake escalation 20.60.61.3-0.60.6-1.11.1-1.0-0.1-0.6-0.80.6-0.50.6-0.50.6-0.90.8-0.90.9-0.9-0.90.8-0.9-1.0
Intermitt. access day 1 inactive lever presses0.10.11.3-0.10.1-0.30.30.0-1.1-0.1-0.10.10.3-0.30.40.70.00.10.0-0.00.20.2-0.00.0-0.1
Intermitt. access day 15 inactive lever presses1.82.02.3-1.51.5-1.21.2-1.31.3-1.5-1.51.4-1.51.5-1.5-1.4-1.41.4-1.51.5-1.4-1.31.5-1.5-1.3
Intermitt. access escalation Index0.20.10.50.3-0.30.1-0.10.3-0.50.30.3-0.30.5-0.40.50.70.4-0.40.3-0.30.30.4-0.40.30.3
Intermittent access day 1 total infusions1.11.32.41.1-1.11.5-1.61.2-0.51.11.4-0.30.9-1.01.0-0.21.2-1.11.3-1.31.31.1-1.21.31.2
Intermittent access day 15 total infusions0.70.81.31.0-1.01.1-1.10.8-0.71.01.1-0.40.8-0.80.80.30.8-0.90.9-0.90.90.9-0.90.90.8
Intermittent access terminal intake (last 3 days)0.40.40.80.8-0.80.9-0.80.5-0.50.80.9-0.00.5-0.50.50.10.5-0.60.7-0.70.60.5-0.60.70.5
Intermittent access total infusions0.50.51.30.8-0.81.2-1.20.6-0.40.81.00.00.5-0.50.5-0.20.6-0.70.8-0.80.70.6-0.70.80.7
Intermittent access day 1 locomotion2.72.73.71.6-1.61.9-1.91.7-1.21.61.9-1.11.5-1.51.50.51.8-1.71.8-1.81.81.7-1.81.81.7
Intermittent access day 15 total locomotion0.80.91.91.1-1.11.4-1.40.9-0.71.11.1-0.30.7-0.80.8-0.01.0-1.10.9-0.90.80.8-0.90.90.9
Intermittent access total locomotion1.11.32.31.3-1.31.5-1.51.0-0.91.31.3-0.30.9-0.90.90.31.2-1.21.2-1.21.11.0-1.21.21.1
Intermittent access standard deviation0.50.60.9-0.50.5-0.60.6-0.90.3-0.5-0.71.0-0.80.8-0.8-0.2-0.80.7-0.90.9-0.9-0.90.8-0.9-0.9
Cocaine induced anxiety0.10.21.60.3-0.3-0.00.0-0.1-1.30.30.30.20.3-0.30.40.80.2-0.30.2-0.20.2-0.0-0.20.2-0.0
Post-drug Anxiety1.71.94.01.5-1.51.2-1.21.1-2.01.51.5-0.71.4-1.41.51.41.4-1.51.4-1.41.31.0-1.31.41.1
Baseline Anxiety0.00.00.4-0.00.00.1-0.10.10.6-0.0-0.10.2-0.20.2-0.2-0.3-0.10.0-0.10.0-0.1-0.20.1-0.10.0
Lifetime Intake0.40.40.80.7-0.70.8-0.90.6-0.20.70.9-0.30.5-0.50.5-0.10.6-0.60.7-0.70.70.7-0.70.70.7
Incentive Sensitization - Responses0.70.73.30.7-0.71.0-1.00.7-1.80.70.70.30.7-0.70.91.20.6-0.80.7-0.70.60.3-0.50.60.5
Incentive Sensitization - Breakpoint0.40.42.90.5-0.50.6-0.60.5-1.70.50.40.50.5-0.60.71.30.4-0.50.4-0.40.40.1-0.30.30.2
Progressive ratio test 1 active lever presses1.21.21.71.1-1.11.0-1.01.0-1.11.11.3-0.91.2-1.21.21.11.0-1.01.2-1.21.21.1-1.11.21.1
Progressive ratio test 1 breakpoint1.31.31.91.2-1.21.1-1.11.1-1.11.21.4-1.01.2-1.21.21.01.1-1.11.3-1.31.21.2-1.11.31.1
Progressive ratio test 1 inactive lever presses0.40.51.3-0.70.7-1.11.2-0.7-0.2-0.7-0.70.7-0.30.4-0.30.3-0.70.7-0.70.7-0.6-0.50.6-0.7-0.7
Progressive ratio test 2 active lever presses1.92.04.01.4-1.41.5-1.51.4-2.01.41.6-0.61.4-1.41.51.51.4-1.51.4-1.41.31.2-1.31.31.2
Progressive ratio test 2 breakpoint1.21.33.41.1-1.11.2-1.21.1-1.91.11.2-0.31.1-1.11.21.41.1-1.21.1-1.11.00.9-1.01.00.9
Progressive ratio test 2 inactive lever presses0.20.21.10.4-0.40.6-0.60.2-1.10.40.50.40.3-0.30.40.50.3-0.40.3-0.30.30.2-0.30.30.2
Total sessions with >9 infusions0.70.81.61.0-1.01.0-1.00.8-0.01.00.9-1.30.7-0.70.6-0.41.0-0.90.9-0.90.91.0-1.00.91.0
Short access day 1 total inactive lever presses0.10.10.70.3-0.30.4-0.40.3-0.30.30.2-0.80.3-0.30.2-0.10.3-0.30.3-0.30.30.4-0.30.30.4
Short access day 10 total inactive lever presses0.30.30.9-0.60.6-0.60.6-0.6-0.4-0.6-0.71.0-0.40.4-0.4-0.2-0.50.5-0.50.5-0.5-0.60.6-0.6-0.6
Short access day 1 total infusions0.00.10.4-0.00.0-0.00.0-0.10.5-0.00.0-0.7-0.10.1-0.2-0.60.1-0.10.0-0.00.10.1-0.10.00.2
Short access day 10 total infusions0.20.30.90.5-0.51.0-1.00.30.30.50.80.20.1-0.20.2-0.40.4-0.40.6-0.50.50.4-0.50.60.5
Short access total infusions0.10.10.80.0-0.00.2-0.3-0.10.70.00.2-0.2-0.20.2-0.3-0.90.1-0.00.1-0.00.10.1-0.10.10.1
Short access day 1 locomotion0.00.00.20.1-0.10.0-0.0-0.20.30.10.1-0.2-0.10.1-0.2-0.50.1-0.0-0.00.00.00.1-0.10.00.0
Short access day 10 total locomotion1.21.31.61.2-1.21.3-1.21.1-0.91.21.2-0.91.0-1.01.10.61.2-1.21.2-1.21.21.2-1.31.21.1
Short access total locomotion0.30.30.70.6-0.60.8-0.80.3-0.00.60.6-0.30.2-0.20.2-0.60.6-0.50.5-0.50.40.6-0.70.50.5
Compulsive drug intake5.45.37.52.0-2.01.9-2.02.7-1.52.02.1-2.72.5-2.52.42.02.4-2.22.4-2.52.62.7-2.42.42.6
One hour access (0.3 mA shock)0.91.01.51.0-1.00.9-0.91.0-1.01.01.2-0.41.0-1.11.10.61.0-0.91.2-1.11.11.1-0.91.21.0
One hour access (shock baseline)0.50.62.4-0.60.6-0.70.7-1.1-0.2-0.6-0.51.5-0.70.7-0.6-0.3-0.80.6-0.70.8-0.9-1.10.9-0.8-1.1
Number of responses in last shaping day1.91.92.7-1.31.3-1.01.0-1.51.2-1.3-1.41.6-1.61.6-1.6-1.5-1.31.3-1.51.5-1.5-1.21.3-1.5-1.5
Context. condit. distance diff. score0.91.11.6-1.11.1-1.11.1-1.10.6-1.1-1.01.0-1.01.0-1.0-0.7-1.31.2-1.01.0-1.0-1.21.2-1.0-1.1
Locomotion velocity, session 10.10.20.80.4-0.40.3-0.30.2-0.90.40.50.00.4-0.40.40.70.4-0.50.3-0.20.20.2-0.40.20.1
Locomotion distance, session 14.96.38.02.8-2.82.7-2.72.6-1.92.82.5-2.42.4-2.42.41.32.7-2.72.5-2.52.42.6-2.72.52.5
Locomotion velocity, session 21.01.22.21.1-1.11.4-1.51.20.21.11.0-1.20.8-0.80.6-0.71.3-1.31.0-1.01.01.2-1.21.11.3
Locomotion distance, session 26.28.811.73.1-3.12.8-2.83.1-2.63.13.0-3.03.0-3.03.01.73.4-3.42.9-3.02.93.1-3.22.93.0
Locomotion velocity, session 30.80.92.6-0.80.8-0.60.5-0.71.6-0.8-1.10.4-1.11.1-1.2-1.6-0.80.9-1.01.0-0.9-0.50.8-0.9-0.7
Locomotion distance, session 31.11.22.61.1-1.11.1-1.11.2-0.51.11.0-1.61.0-1.00.90.31.2-1.11.0-1.01.01.3-1.21.01.2
Stereotopy head waving bouts, day 34.35.16.0-2.42.4-2.42.3-2.22.0-2.4-2.42.3-2.22.3-2.2-2.2-2.22.2-2.32.3-2.3-2.02.3-2.2-2.3
Stereotopy head waving duration, day 33.03.64.3-1.81.8-1.71.7-1.92.0-1.8-1.92.1-2.02.0-2.0-2.0-2.02.0-1.91.9-1.9-1.91.9-1.8-1.9
Locomotion velocity, session 71.21.32.61.3-1.31.6-1.61.3-0.11.31.2-1.20.9-0.90.8-0.81.1-1.11.1-1.11.11.1-1.21.11.3
Locomotion distance, session 76.38.110.43.0-3.03.2-3.23.1-2.03.03.0-2.72.7-2.72.61.12.9-3.02.9-3.02.92.8-3.02.93.0
Stereotopy head waving bouts, day 70.50.61.0-0.70.7-0.90.9-0.80.9-0.7-0.80.6-0.70.7-0.8-1.0-0.70.9-0.80.8-0.7-0.50.7-0.7-0.7
Stereotopy head waving duration, day 70.40.51.4-0.60.6-0.70.7-0.71.2-0.6-0.80.4-0.80.8-0.8-1.0-0.70.8-0.70.7-0.7-0.30.6-0.7-0.6
Locomotion velocity, session 81.01.21.8-1.11.1-1.31.3-1.01.2-1.1-1.10.6-0.90.9-1.0-1.0-1.11.2-1.21.2-1.1-0.91.0-1.1-1.0
Locomotion distance, session 80.50.81.20.9-0.90.7-0.70.9-1.00.90.9-1.11.0-0.90.90.50.9-0.90.9-0.90.90.9-0.90.90.8
Degree of sensitization distance0.30.30.90.6-0.60.9-0.90.6-0.50.60.7-0.10.4-0.40.40.10.6-0.70.6-0.60.50.3-0.50.60.6
Degree of sensitization stereotypy0.20.20.30.4-0.40.1-0.10.4-0.40.40.4-0.50.5-0.50.50.50.4-0.30.4-0.40.50.6-0.40.50.4
Condit. Reinf. active minus inactive responses1.01.11.51.0-1.00.9-0.91.2-1.11.01.0-0.71.2-1.21.21.11.0-1.11.1-1.11.11.1-1.01.11.1
Condit. Reinf. active-inactive response ratio0.10.10.5-0.30.3-0.40.4-0.0-0.2-0.3-0.20.5-0.00.00.00.7-0.20.1-0.20.2-0.2-0.20.2-0.2-0.2
Condit. Reinf. active responses1.21.41.81.1-1.11.0-1.01.3-1.21.11.1-0.91.3-1.31.31.01.2-1.31.2-1.31.31.3-1.21.21.2
Condit. Reinf. inactive responses1.41.62.11.4-1.41.0-1.01.0-1.41.41.3-1.41.3-1.31.20.81.4-1.41.3-1.31.31.4-1.31.41.2
Incentive salience index mean2.02.43.21.4-1.41.2-1.21.6-1.81.41.5-1.31.7-1.71.71.51.6-1.71.6-1.61.61.5-1.51.51.5
Condit. Reinf. lever presses2.83.86.01.9-1.91.5-1.51.8-2.51.92.0-1.82.1-2.12.11.62.2-2.32.0-2.01.91.9-2.01.91.8
Time in familiar zone, hab. session 10.30.31.90.3-0.30.1-0.10.2-1.30.30.5-0.30.6-0.60.71.40.5-0.70.5-0.50.50.1-0.30.50.3
Time in novel zone, hab. session 13.23.16.2-1.61.6-1.41.4-1.42.5-1.6-1.81.3-1.81.8-1.8-2.2-2.02.3-1.81.8-1.7-1.31.7-1.8-1.5
Total zone transitions, hab. session 16.49.110.13.2-3.22.9-2.83.1-2.63.23.0-2.93.1-3.13.12.23.2-3.13.0-3.03.03.1-3.23.03.0
Total locomotion distance, hab. session 13.95.66.62.5-2.52.3-2.22.6-2.02.52.4-2.32.5-2.52.51.22.4-2.32.5-2.52.42.4-2.42.52.4
Locomotion velocity, hab. session 15.47.78.73.0-3.02.8-2.72.8-2.53.02.9-2.42.9-2.92.81.52.9-2.92.9-2.92.82.7-2.92.92.8
Time in familiar zone, hab. session 21.51.62.9-1.41.4-1.71.7-1.20.5-1.4-1.31.2-1.11.1-1.00.2-1.21.3-1.41.4-1.3-1.11.3-1.4-1.4
Time in novel zone, hab. session 20.30.30.60.7-0.70.7-0.70.4-0.30.70.5-0.40.5-0.50.4-0.40.5-0.50.6-0.60.50.3-0.50.60.5
Total zone transitions, hab. session 24.76.17.22.6-2.62.2-2.22.5-2.32.62.5-2.22.6-2.62.51.92.6-2.72.5-2.52.42.5-2.62.52.4
Total locomotion distance, hab. session 21.31.82.41.5-1.51.4-1.41.3-1.21.51.4-1.01.3-1.31.30.31.4-1.41.4-1.41.31.3-1.41.41.3
Locomotion velocity, hab. session 21.52.02.61.6-1.61.6-1.51.5-1.01.61.5-1.11.4-1.41.40.31.4-1.41.5-1.51.41.4-1.51.51.4
Novel to familiar place preference ratio0.30.31.20.6-0.60.6-0.50.6-0.60.60.6-0.40.7-0.70.71.10.10.10.6-0.60.60.3-0.40.60.5
Novelty place preference0.20.20.90.4-0.40.4-0.40.5-0.50.40.5-0.40.6-0.60.61.0-0.10.20.5-0.40.50.2-0.30.50.4
Time in novel zone, NPP test0.10.10.90.2-0.20.1-0.10.4-0.40.20.2-0.20.5-0.40.50.9-0.20.40.2-0.20.30.1-0.10.20.2
Total zone transitions, NPP test6.18.811.63.3-3.32.7-2.62.9-2.83.33.0-3.13.0-3.03.01.93.3-3.42.9-2.92.82.9-3.12.92.9
Total locomotion distance, NPP test2.53.55.02.2-2.21.9-1.91.7-1.92.22.0-1.71.9-1.91.80.72.0-2.11.9-1.91.71.6-2.01.91.8
Locomotion velocity, NPP test3.04.36.02.4-2.42.3-2.22.0-1.72.42.2-1.92.0-2.01.90.52.2-2.32.1-2.12.01.8-2.22.12.1
Pavlov. Cond. lever latency1.62.16.0-1.31.3-0.80.7-1.32.5-1.3-1.41.3-1.71.7-1.7-1.8-1.51.6-1.31.3-1.3-1.31.4-1.2-1.2
Pavlov. Cond. magazine entry latency0.20.31.70.0-0.0-0.30.40.5-1.10.00.2-0.40.7-0.70.81.30.2-0.10.3-0.30.40.5-0.20.30.2
Pavlov. Cond. change in total contacts3.84.06.61.7-1.71.4-1.32.0-2.61.71.9-1.92.3-2.32.42.42.0-2.02.0-2.02.12.0-1.92.01.9
Pavlov. Cond. index score1.01.34.70.8-0.80.3-0.21.1-2.20.81.0-1.01.5-1.41.62.01.0-1.01.0-1.01.11.1-1.01.00.9
Pavlov. Cond. latency score1.01.34.40.8-0.80.4-0.31.1-2.10.81.0-1.11.4-1.41.51.71.0-1.01.0-1.01.11.1-1.01.00.9
Pavlov. Cond. lever contacts2.73.27.51.7-1.71.1-1.11.6-2.71.71.8-1.82.1-2.02.11.91.9-2.01.7-1.71.71.6-1.81.71.6
Pavlov. Cond. magazine entry number0.60.82.9-0.60.6-0.30.3-1.01.5-0.6-0.80.7-1.11.1-1.2-1.7-0.70.6-0.80.8-0.9-0.80.7-0.8-0.7
Pavlov. Cond. intertrial magazine entries1.72.03.31.7-1.71.8-1.81.2-1.01.71.5-0.71.1-1.21.10.51.7-1.81.5-1.51.41.3-1.51.51.4
Pavlov. Cond. lever-magazine prob. diff.0.91.14.10.6-0.60.1-0.11.0-2.00.60.8-0.91.3-1.31.42.00.9-0.80.9-0.91.01.0-0.80.80.7
Pavlov. Cond. response bias0.81.03.80.7-0.70.2-0.11.0-1.90.70.8-1.01.3-1.31.41.90.9-0.80.8-0.90.90.9-0.80.80.7
Bone: apparent density0.91.52.9-1.11.1-1.11.1-1.20.9-1.1-1.11.5-1.11.1-1.0-0.1-1.61.7-1.11.2-1.1-1.51.3-1.1-1.3
Bone surface0.20.40.8-0.50.5-0.20.2-0.60.7-0.5-0.50.9-0.70.7-0.7-0.4-0.90.9-0.50.6-0.5-0.80.7-0.5-0.6
Bone volume0.71.22.2-0.90.9-0.50.5-1.01.4-0.9-0.81.4-1.21.2-1.2-0.9-1.41.5-0.91.0-1.0-1.31.1-0.9-1.0
Bone: connectivity density0.20.41.4-0.60.6-0.50.6-0.50.4-0.6-0.50.5-0.40.5-0.40.4-1.01.2-0.60.6-0.5-0.70.7-0.6-0.6
Bone: cortical apparent density4.25.47.42.4-2.42.5-2.52.5-0.62.42.5-2.72.2-2.22.10.02.3-2.12.5-2.52.52.6-2.52.52.7
Bone: cortical area0.30.51.0-0.60.6-0.30.3-0.60.6-0.6-0.61.0-0.80.8-0.8-0.9-0.70.6-0.60.6-0.7-0.90.7-0.6-0.6
Bone: cortical porosity0.20.30.6-0.50.5-0.40.4-0.50.1-0.5-0.60.8-0.50.5-0.5-0.5-0.40.3-0.60.5-0.6-0.60.5-0.6-0.6
Bone: cortical porosity0.10.10.5-0.30.3-0.20.2-0.3-0.1-0.3-0.40.7-0.40.4-0.4-0.5-0.20.2-0.40.4-0.4-0.40.3-0.4-0.4
Bone: cortical thickness0.20.41.8-0.60.6-0.30.2-0.41.1-0.6-0.50.6-0.70.7-0.7-1.4-0.60.6-0.50.5-0.6-0.60.6-0.5-0.4
Bone: cortical thickness0.20.21.20.4-0.40.4-0.40.70.30.40.4-1.10.5-0.50.40.20.00.20.4-0.40.50.6-0.30.50.6
Bone: cortical tissue density4.66.08.22.5-2.52.6-2.62.7-0.62.52.6-2.92.3-2.32.20.12.5-2.32.6-2.62.72.8-2.62.72.8
Bone: elastic displacement0.00.00.10.0-0.0-0.10.2-0.1-0.10.00.0-0.1-0.00.00.0-0.0-0.20.2-0.00.0-0.1-0.20.1-0.0-0.1
Bone: elastic work0.00.00.10.3-0.30.1-0.1-0.20.10.30.3-0.10.0-0.00.0-0.2-0.20.20.2-0.20.1-0.2-0.10.20.0
Bone: endosteal estimation0.00.00.10.2-0.20.3-0.3-0.1-0.30.20.20.3-0.10.0-0.00.2-0.20.20.1-0.10.1-0.2-0.00.1-0.1
Bone: endosteal perimeter0.10.10.5-0.30.3-0.20.2-0.4-0.2-0.3-0.30.7-0.40.4-0.4-0.1-0.40.3-0.30.3-0.4-0.60.4-0.4-0.4
Bone: final force0.00.10.60.0-0.00.1-0.0-0.2-0.30.0-0.00.8-0.20.1-0.10.1-0.30.2-0.00.0-0.1-0.50.1-0.0-0.3
Bone: final moment0.10.10.7-0.20.2-0.20.2-0.4-0.2-0.2-0.20.8-0.30.3-0.20.0-0.40.3-0.20.2-0.3-0.60.3-0.2-0.4
Bone: marrow area0.00.10.20.3-0.30.4-0.4-0.0-0.40.30.30.20.1-0.10.10.3-0.10.10.2-0.20.2-0.1-0.10.20.1
Bone: maximum diameter0.10.30.8-0.50.5-0.40.4-0.5-0.2-0.5-0.50.9-0.50.5-0.50.1-0.50.4-0.50.5-0.5-0.70.5-0.5-0.6
Bone: maximum force0.40.61.8-0.60.6-0.40.4-0.90.6-0.6-0.61.3-0.90.9-0.9-0.6-0.90.9-0.70.7-0.8-1.10.8-0.7-0.8
Bone: maximum moment0.50.91.7-0.80.8-0.60.6-1.00.7-0.8-0.81.3-1.11.0-1.0-0.7-1.11.0-0.80.9-0.9-1.20.9-0.8-1.0
Bone: minimum diameter0.10.10.80.2-0.20.6-0.60.00.40.20.20.5-0.30.2-0.3-0.9-0.00.00.1-0.10.1-0.1-0.10.10.1
Bone: periosteal estimation0.10.31.1-0.40.4-0.10.1-0.60.0-0.4-0.31.0-0.60.6-0.5-0.3-0.60.6-0.40.4-0.5-0.80.5-0.4-0.6
Bone: periosteal perimeter0.71.11.9-1.11.1-0.90.8-1.10.3-1.1-1.11.4-1.11.1-1.1-0.5-1.10.9-1.11.1-1.2-1.41.1-1.1-1.2
Bone: post-yield work0.70.91.2-1.01.0-0.70.6-1.01.1-1.0-0.91.1-1.11.1-1.1-1.1-1.01.1-0.90.9-0.9-0.90.9-0.9-0.9
Bone: stiffness0.00.00.40.1-0.10.3-0.3-0.0-0.00.10.10.6-0.20.2-0.10.0-0.10.10.1-0.1-0.0-0.30.00.0-0.0
Bone: tissue strength0.80.81.9-0.90.9-0.60.5-1.01.0-0.9-0.81.0-1.11.1-1.2-1.4-0.60.4-0.80.8-0.9-1.00.8-0.8-0.8
Bone: trabecular number0.00.10.4-0.00.0-0.00.1-0.10.1-0.00.00.4-0.00.00.00.5-0.50.6-0.00.10.0-0.30.2-0.0-0.2
Bone: trabecular spacing0.20.21.2-0.30.3-0.90.9-0.3-1.1-0.3-0.30.30.1-0.10.20.9-0.0-0.1-0.30.3-0.3-0.20.2-0.3-0.4
Bone: trabecular thickness3.74.49.6-2.02.0-1.11.1-1.93.1-2.0-1.91.7-2.42.4-2.5-2.8-2.32.3-2.02.0-2.0-2.12.1-2.0-1.7
Bone: trabecular tissue density0.10.11.5-0.10.10.1-0.20.00.4-0.1-0.1-0.3-0.20.2-0.3-1.20.5-0.6-0.1-0.0-0.10.1-0.1-0.00.1
Breakpoint value in progressive ratio session2.02.24.01.1-1.11.0-1.01.9-0.81.11.2-2.01.6-1.61.51.71.6-1.31.5-1.61.72.0-1.51.61.7
Distance traveled before self-admin3.33.56.11.8-1.81.5-1.51.8-2.51.81.8-1.52.1-2.12.12.31.8-1.91.9-1.91.91.7-1.81.81.7
Distance traveled after self-admin0.30.43.2-0.40.4-0.80.9-0.3-0.8-0.4-0.40.10.0-0.00.21.8-0.50.6-0.40.4-0.4-0.30.5-0.4-0.6
Delta time in closed arm before/after self-admin0.10.10.7-0.30.30.2-0.2-0.20.8-0.3-0.20.4-0.40.4-0.4-0.8-0.40.3-0.20.2-0.2-0.50.3-0.2-0.1
Delta time in open arm before/after self-admin0.00.00.1-0.00.0-0.10.10.00.2-0.0-0.1-0.10.0-0.0-0.0-0.10.00.00.1-0.10.1-0.1-0.00.10.1
Diff in mean of infusions in LGA sessions1.71.92.81.2-1.21.2-1.21.7-1.31.21.4-1.01.5-1.51.61.71.3-1.11.5-1.51.51.5-1.31.61.4
Extinction: sum of active levers before priming1.41.43.01.2-1.21.7-1.71.2-0.21.21.3-1.00.9-0.90.8-0.11.1-1.11.4-1.31.10.9-1.11.31.3
Active lever presses in extinction session 60.30.30.8-0.80.8-0.90.9-0.20.3-0.8-0.70.0-0.20.2-0.20.5-0.60.8-0.50.5-0.4-0.10.5-0.5-0.4
Delta distance traveled before/after self-admin3.13.34.1-1.81.8-1.91.9-1.91.4-1.8-1.81.5-1.81.8-1.8-0.7-2.02.0-1.92.0-2.0-1.81.9-1.9-2.0
Delta ambulatory time before/after self-admin3.03.33.9-1.81.8-1.81.9-1.91.4-1.8-1.81.9-1.81.8-1.7-0.8-2.02.0-1.92.0-1.9-1.71.9-1.9-2.0
Time in closed arm before self-admin2.63.03.9-1.61.6-1.21.2-1.51.4-1.6-1.81.9-1.91.8-1.8-2.0-1.81.8-1.91.9-1.9-1.91.8-1.9-1.8
Time in closed arm after self-admin2.62.75.3-1.41.4-0.50.5-1.51.7-1.4-1.52.0-1.91.9-1.9-2.3-1.71.6-1.61.6-1.7-2.01.6-1.7-1.6
Time in open arm before self-admin0.60.61.60.7-0.70.5-0.50.7-1.10.70.9-0.70.8-0.80.91.20.8-0.90.8-0.80.70.8-0.70.80.7
Time in open arm after self-admin0.30.30.60.5-0.50.1-0.10.5-0.70.50.5-0.70.7-0.70.60.80.7-0.70.6-0.60.60.6-0.50.60.5
Sum of active levers in priming session hrs 5-64.64.66.32.1-2.12.1-2.12.4-0.92.12.2-2.42.1-2.12.01.32.2-2.02.3-2.32.32.5-2.22.32.4
Time to tail flick, vehicle, before self-admin0.80.81.60.8-0.80.6-0.61.2-0.40.80.8-0.91.1-1.11.10.61.0-0.81.0-1.01.11.3-0.91.01.1
Time to tail flick, vehicle, after self-admin0.60.61.2-0.80.8-0.30.3-0.70.9-0.8-0.70.7-0.90.9-0.9-0.7-0.90.7-0.90.9-0.9-1.10.8-0.9-0.7
Time to tail flick, test, before self-admin1.21.23.1-1.11.1-0.80.7-0.61.8-1.1-1.10.6-1.11.1-1.2-1.4-1.01.3-1.11.1-1.0-0.71.0-1.1-0.8
Time to tail flick, test, after self-admin0.90.92.4-1.11.1-0.90.8-0.61.6-1.1-0.90.5-1.01.0-1.0-1.1-1.01.2-0.90.9-0.8-0.50.9-0.9-0.7
Delta time to tail flick, vehicle, before/after SA2.62.54.0-1.51.5-1.21.2-1.61.2-1.5-1.51.4-1.71.7-1.7-1.0-1.71.5-1.71.7-1.8-2.01.7-1.8-1.7
Delta time to tail flick, test, before/after SA0.30.30.60.4-0.40.1-0.10.5-0.30.40.5-0.80.6-0.60.60.60.5-0.60.5-0.50.60.7-0.50.60.5
Ambulatory time before self-admin2.52.76.31.6-1.61.4-1.41.6-2.51.61.6-1.11.7-1.71.82.11.6-1.71.6-1.61.51.2-1.51.51.3
Ambulatory time after self-admin0.30.31.2-0.50.5-0.60.6-0.4-0.5-0.5-0.40.5-0.30.3-0.11.1-0.60.6-0.50.5-0.6-0.50.6-0.5-0.7
Total heroin consumption0.20.31.40.1-0.1-0.30.30.6-0.30.10.3-0.70.7-0.70.71.20.4-0.20.5-0.50.70.8-0.40.50.5
Area under the delay curve0.00.00.20.1-0.10.2-0.20.10.20.1-0.1-0.5-0.00.0-0.10.20.0-0.1-0.10.10.0-0.0-0.1-0.10.1
Delay disc. indifference point, 0s delay0.10.10.30.4-0.40.5-0.5-0.2-0.20.40.2-0.3-0.10.0-0.10.20.0-0.20.0-0.0-0.0-0.4-0.10.00.0
Delay disc. indifference point, 16s delay1.51.51.9-1.31.3-1.31.3-1.01.4-1.3-1.40.8-1.21.2-1.3-0.5-1.31.4-1.41.4-1.2-1.11.2-1.3-1.2
Delay disc. indifference point, 2s delay0.30.31.00.8-0.81.0-1.00.20.10.80.7-0.50.2-0.20.10.10.4-0.70.5-0.50.4-0.0-0.50.50.4
Delay disc. indifference point, 24s delay0.60.61.10.6-0.60.7-0.71.1-0.60.60.6-0.90.8-0.80.80.90.7-0.70.7-0.70.90.9-0.80.70.8
Delay disc. indifference point, 4s delay1.01.12.91.2-1.21.7-1.71.20.51.21.0-1.70.7-0.70.5-0.30.8-0.80.9-0.90.90.9-1.00.91.2
Delay disc. indifference point, 8s delay0.10.10.30.3-0.30.3-0.30.3-0.10.30.0-0.60.2-0.20.20.30.3-0.40.1-0.20.30.2-0.30.20.3
Delay discount exponential model param0.10.10.4-0.20.2-0.40.4-0.3-0.2-0.2-0.00.6-0.10.1-0.1-0.2-0.10.2-0.00.1-0.2-0.10.2-0.1-0.3
Delay discount hyperbolic model param0.10.10.5-0.40.4-0.60.6-0.4-0.3-0.4-0.20.7-0.20.2-0.1-0.1-0.20.3-0.20.2-0.3-0.20.3-0.2-0.4
Fecal boli incidents, locomotor time 14.14.56.5-2.32.3-2.42.3-1.72.0-2.3-2.61.7-1.91.9-1.9-1.3-2.12.1-2.42.3-2.2-1.82.2-2.4-2.0
Change in fecal boli incidents, locomotor task2.72.53.81.7-1.72.0-1.91.5-1.21.71.9-1.21.4-1.51.51.41.4-1.51.7-1.71.61.4-1.61.71.6
Time >=10cm from walls, locomotor time 10.40.42.40.4-0.40.00.00.1-1.50.40.50.10.7-0.70.81.40.3-0.40.4-0.40.40.1-0.30.40.1
Bouts of movement, locomotor time 10.50.52.8-0.80.8-0.30.3-0.41.3-0.8-0.80.2-0.80.8-0.9-1.7-0.50.5-0.60.5-0.5-0.30.5-0.5-0.4
Total resting periods, locomotor time 10.91.03.0-1.11.1-0.70.6-0.71.5-1.1-1.10.6-1.11.1-1.2-1.7-0.80.8-0.90.9-0.8-0.60.8-0.8-0.7
Rest time, locomotor task time 10.10.10.3-0.20.2-0.00.0-0.40.5-0.2-0.40.1-0.50.5-0.5-0.4-0.1-0.0-0.30.2-0.5-0.40.3-0.3-0.3
Distance moved, locomotor task time 12.42.64.51.5-1.51.2-1.21.8-1.51.51.7-1.21.8-1.81.92.11.5-1.41.6-1.61.81.6-1.61.61.6
Vertical activity count, locomotor time 10.50.61.20.7-0.70.4-0.40.8-1.00.70.8-0.30.9-0.91.01.10.6-0.50.7-0.70.80.7-0.70.70.7
Time >=10cm from walls, locomotor time 20.50.51.40.6-0.60.5-0.50.8-1.20.60.6-0.40.8-0.80.81.20.7-0.80.6-0.60.60.5-0.60.60.6
Bouts of movement, locomotor time 20.00.00.20.2-0.20.00.0-0.2-0.20.20.20.20.0-0.00.10.3-0.1-0.10.4-0.30.2-0.40.10.3-0.0
Total resting periods, locomotor time 20.10.10.30.2-0.2-0.00.0-0.3-0.40.20.30.30.1-0.10.10.4-0.1-0.20.4-0.40.1-0.50.00.4-0.1
Rest time, locomotor task time 20.30.40.90.6-0.60.6-0.60.5-0.40.60.5-0.80.5-0.50.50.50.9-0.90.6-0.70.50.7-0.70.60.6
Distance moved, locomotor task time 20.10.10.40.2-0.20.5-0.50.70.50.20.3-0.60.2-0.20.2-0.20.10.00.2-0.20.40.5-0.30.30.5
Vertical activity count, locomotor time 20.10.10.30.3-0.30.5-0.50.5-0.00.30.4-0.20.3-0.30.3-0.20.10.00.3-0.30.30.2-0.30.30.4
Weight adjusted by age0.10.10.50.1-0.10.3-0.30.20.20.10.4-0.70.2-0.20.20.1-0.00.10.3-0.30.40.1-0.00.30.3
Seeking ratio, delayed vs. immediate footshock1.31.53.4-1.01.0-1.01.0-1.80.8-1.0-1.21.4-1.41.4-1.3-0.6-1.21.1-1.21.2-1.2-1.61.3-1.2-1.3
Locomotion in novel chamber0.50.61.60.9-0.90.9-0.80.7-1.20.91.1-0.20.8-0.80.91.30.4-0.40.9-0.80.80.5-0.50.80.5
Locomotion in novel chamber post-restriction0.50.53.4-0.10.1-0.00.1-1.2-0.7-0.1-0.01.8-0.80.7-0.7-0.5-0.50.0-0.40.4-0.8-1.40.6-0.5-1.0
Progressive ratio0.20.21.10.1-0.1-0.70.7-1.0-1.10.10.30.20.0-0.00.10.70.1-0.4-0.10.1-0.2-0.60.0-0.1-0.5
Food seeking constrained by brief footshock0.10.10.9-0.30.3-0.91.0-0.6-0.2-0.3-0.10.2-0.00.1-0.00.3-0.20.2-0.10.1-0.30.00.2-0.0-0.4
Seeking ratio, punishment vs. effort0.30.41.50.3-0.30.7-0.71.20.50.30.2-0.60.5-0.50.5-0.20.4-0.20.6-0.70.71.1-0.50.70.8
Run reversals in cocaine runway, females0.10.10.50.2-0.20.6-0.60.60.70.20.0-0.60.1-0.1-0.0-0.20.2-0.00.1-0.10.10.6-0.20.10.4
Run reversals in cocaine runway, males0.70.72.3-0.50.5-0.80.9-1.4-0.8-0.5-0.61.5-0.70.7-0.60.3-0.60.2-0.70.7-0.9-1.30.8-0.8-1.1
Latency to leave start box in cocaine runway4.75.17.6-2.12.1-1.61.6-2.42.8-2.1-2.12.5-2.52.4-2.4-2.1-2.72.7-2.02.0-2.1-2.72.4-2.0-2.1
Latency to leave start box in cocaine runway, F7.58.311.0-2.72.7-2.12.1-3.13.1-2.7-2.82.9-3.23.2-3.2-2.7-3.23.1-2.72.8-2.8-3.33.0-2.7-2.8
Latency to leave start box in cocaine runway, M0.10.10.3-0.10.1-0.10.10.00.2-0.10.20.60.0-0.10.10.3-0.40.60.3-0.20.2-0.40.20.30.1
Cd content in liver0.70.74.10.6-0.6-0.10.20.3-2.00.60.6-0.01.0-0.91.12.00.7-0.80.6-0.60.60.3-0.60.50.3
Co content in liver0.10.10.80.1-0.1-0.20.2-0.1-0.90.10.10.30.2-0.20.30.40.2-0.30.1-0.10.00.0-0.10.0-0.1
Cu content in liver11.313.615.03.9-3.93.8-3.83.7-3.33.93.9-2.93.7-3.73.72.33.8-3.83.9-3.93.83.6-3.83.93.7
Fe content in liver2.63.14.02.0-2.02.0-2.01.5-1.52.01.9-1.21.6-1.61.61.11.9-2.01.9-1.91.81.6-1.91.91.7
K content in liver1.31.33.71.3-1.31.9-1.91.0-0.11.31.2-0.40.7-0.70.6-0.81.1-1.21.2-1.21.10.8-1.11.21.3
Mg content in liver4.14.28.92.3-2.33.0-3.02.0-1.02.32.3-1.31.6-1.71.6-0.32.0-2.22.2-2.22.01.5-2.02.22.2
Mn content in liver3.13.65.31.9-1.91.7-1.72.0-1.21.91.9-2.32.0-2.01.91.12.0-1.92.0-2.02.01.9-2.02.02.1
Na content in liver0.70.82.11.0-1.01.4-1.50.90.01.01.0-0.60.6-0.60.6-0.60.7-0.71.0-0.90.90.6-0.80.91.0
Rb content in liver0.30.30.90.5-0.50.2-0.20.5-0.70.50.5-0.30.6-0.60.60.70.8-0.80.5-0.50.60.9-0.70.50.4
Se content in liver0.10.10.4-0.10.1-0.20.2-0.3-0.3-0.1-0.10.6-0.10.1-0.10.2-0.10.0-0.10.1-0.2-0.60.2-0.1-0.3
Sr content in liver0.60.51.30.8-0.81.1-1.10.70.50.80.8-0.90.4-0.40.3-0.70.7-0.60.8-0.80.70.5-0.70.70.9
Zn content in liver0.60.72.50.8-0.80.9-0.80.5-1.60.80.9-0.00.8-0.80.90.50.9-1.10.9-0.90.70.2-0.70.80.6