Hub : Genes

Pde2a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability ENSRNOG00000019560 0.06 0.04 2.4e-03 0.02 0.03 0.02 0.02 3.3e-02 1.4e-02 2.2e-02 3.4e-02
2 Brain alternative TSS ENSRNOT00000026586 0.13 0.09 6.9e-06 0.06 0.06 0.07 0.06 1.2e-06 3.7e-06 3.8e-07 1.9e-06
3 Brain alternative TSS ENSRNOT00000120138 0.13 0.09 8.0e-06 0.06 0.06 0.07 0.06 1.3e-06 3.0e-06 4.5e-07 2.3e-06
4 Brain gene expression ENSRNOG00000019560 0.1 0.05 3.3e-07 0.07 0.07 0.08 0.07 3.3e-07 4.8e-07 3.6e-08 3.2e-07
5 Brain mRNA stability ENSRNOG00000019560 0.08 0.05 1.2e-07 0.08 0.08 0.07 0.08 4.7e-08 8.6e-08 3.1e-07 4.5e-08
6 IL mRNA stability ENSRNOG00000019560 0.61 0.24 1.7e-06 0.16 0.17 0.16 0.12 1.3e-04 6.8e-05 1.3e-04 8.0e-04
7 Liver gene expression ENSRNOG00000019560 0.04 0.03 1.8e-04 0.01 0.03 0.02 0.02 7.0e-03 4.2e-04 1.2e-03 3.3e-03
8 Liver mRNA stability ENSRNOG00000019560 0.05 0.03 1.1e-04 0.01 0.02 0.02 0.02 1.2e-02 1.2e-03 2.4e-03 4.5e-03
9 NAcc isoform ratio ENSRNOT00000090959 0.06 0.05 6.7e-03 0.02 0.02 0.01 0.02 2.0e-02 7.2e-03 8.9e-02 1.1e-02
10 NAcc mRNA stability ENSRNOG00000019560 0.06 0.05 5.0e-03 0.03 0.02 0.01 0.02 1.5e-03 9.1e-03 7.2e-02 6.9e-03
11 OFC isoform ratio ENSRNOT00000120138 0.22 0.14 1.5e-03 0.01 0.09 0.04 0.04 1.6e-01 4.6e-03 3.2e-02 3.4e-02
12 OFC mRNA stability ENSRNOG00000019560 0.23 0.15 1.4e-03 0.01 0.04 0.02 0.01 1.7e-01 3.8e-02 1.1e-01 2.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.61.88.70.80.5-0.51.91.52.9-0.31.70.7-0.7-0.11.6
BMI without tail0.30.71.40.9-1.21.2-0.01.10.5-0.7-0.9-1.0-0.6-0.70.2
Body weight0.62.66.8-0.2-2.62.6-2.0-0.21.00.1-1.5-2.4-1.70.2-1.3
Epididymis fat weight0.41.03.4-1.0-0.60.6-0.2-0.8-0.41.20.4-1.3-1.81.2-0.9
Glucose0.50.81.70.90.8-0.80.90.90.5-0.70.41.11.3-0.71.2
Heart weight0.50.71.61.1-0.30.3-0.60.80.2-1.2-1.00.41.1-1.30.5
Left kidney weight0.51.53.71.0-1.91.9-1.30.90.8-1.0-1.6-1.3-0.3-1.0-0.2
Right kidney weight0.41.13.10.4-1.81.8-1.40.30.5-0.4-1.3-1.4-0.7-0.4-0.6
Tail length3.510.427.00.4-4.64.6-4.7-0.5-2.4-1.0-5.2-3.9-0.7-1.2-3.0
Length with tail2.79.925.9-0.5-4.64.6-5.1-1.2-0.9-0.0-4.2-4.1-1.6-0.2-3.3
Length without tail0.30.61.6-0.8-0.70.7-1.3-0.80.80.70.1-0.6-0.70.7-0.8
Liver weight, left3.15.08.6-2.7-1.31.3-2.1-2.9-1.22.4-0.4-2.7-2.72.4-2.9
Liver weight, right4.67.713.1-3.0-2.22.2-2.6-3.3-2.02.7-1.0-3.5-3.32.7-3.6
Parametrial fat weight0.30.52.0-0.20.7-0.71.40.10.10.61.30.1-0.60.70.7
Retroperitoneal fat weight2.06.616.5-2.7-2.52.5-1.4-2.20.22.90.4-3.5-4.13.0-2.6
Intraocular pressure1.82.55.70.82.4-2.42.00.6-1.6-0.70.81.91.9-0.71.6
Extensor digitorum longus weight0.10.30.9-0.4-0.50.5-0.4-0.30.40.60.3-0.8-1.00.7-0.3
Soleus weight0.92.75.7-1.4-1.81.8-1.8-1.40.41.3-0.5-2.4-2.41.4-1.8
Tibialis anterior weight0.31.02.2-0.4-1.51.5-1.4-0.50.10.3-0.9-1.4-1.00.3-1.1
Tibia length0.51.33.61.1-0.30.3-0.90.61.6-1.5-1.30.61.9-1.50.4
Number of licking bursts2.12.55.9-2.10.5-0.50.4-1.8-0.92.41.8-0.7-2.02.4-1.0
Food consumed during 24 hour testing period2.42.97.22.3-0.00.0-0.11.91.1-2.4-1.31.32.7-2.41.5
Times rat made contact with spout0.30.40.6-0.7-0.50.5-0.8-0.8-0.10.7-0.1-0.7-0.40.7-0.7
Mean time between licks in bursts4.56.315.50.6-3.93.9-3.70.10.4-1.1-3.8-2.9-1.0-1.2-2.0
Mean num. licks in bursts1.72.14.71.9-0.70.7-0.71.50.9-2.1-1.80.51.9-2.20.7
Std. dev. time between licks in bursts2.63.17.7-0.4-2.62.6-2.8-0.70.10.1-2.0-2.4-1.40.1-1.8
Water consumed over 24 hours0.30.30.7-0.60.8-0.80.5-0.6-0.40.60.80.40.20.70.1
Indifference point 0 sec1.22.04.21.9-0.90.9-0.81.51.6-2.0-1.60.31.4-2.00.8
Indifference point AUC0.40.51.2-0.1-1.11.1-0.3-0.2-0.30.0-0.9-1.1-0.8-0.0-0.7
Indifference point function ln k0.60.92.40.90.8-0.80.00.80.8-1.00.11.31.5-1.01.0
Indifference point function log k0.60.92.40.90.8-0.80.00.80.8-1.00.11.31.5-1.01.0
Delay discounting total patch changes 0 sec1.11.73.51.7-0.80.8-0.71.51.6-1.9-1.30.21.2-1.90.8
Delay discounting total patch changes 12 sec1.01.43.50.3-1.91.9-1.60.20.8-0.5-1.6-1.4-0.6-0.5-0.8
Delay discounting total patch changes 18 sec0.40.61.40.9-0.80.8-0.70.50.6-1.0-1.2-0.40.3-1.00.1
Delay discounting total patch changes 24 sec0.81.02.60.4-1.61.6-1.20.20.2-0.6-1.5-1.2-0.6-0.6-0.6
Delay discounting total patch changes 6 sec0.20.30.80.9-0.40.4-0.10.80.4-0.9-0.50.10.2-0.90.4
Delay discounting time to switch 0 sec1.72.75.6-2.21.4-1.40.9-1.8-1.22.32.10.0-1.42.4-0.8
Delay discounting water rate 0 sec1.21.94.31.9-0.90.9-0.81.61.0-2.0-1.60.21.3-2.10.7
Delay discounting water rate 12 sec2.23.37.32.60.0-0.00.62.72.4-2.4-0.41.31.4-2.42.1
Delay discounting water rate 18 sec1.72.24.82.2-1.01.0-0.32.21.1-2.2-1.40.21.1-2.21.1
Delay discounting water rate 24 sec1.01.43.71.30.6-0.60.61.41.9-1.30.31.31.2-1.21.4
Delay discounting water rate 6 sec1.11.63.61.70.1-0.10.31.71.9-1.6-0.21.01.3-1.61.4
Locomotor activity0.40.62.00.9-0.80.80.21.01.4-0.9-0.50.00.1-0.90.4
Locomotor testing distance1.22.03.51.7-1.71.7-0.81.61.9-1.8-1.5-0.30.6-1.70.5
Locomotor testing rearing1.01.54.40.4-2.12.1-1.60.30.7-0.6-1.6-1.3-0.5-0.6-0.7
Light reinforcement 11.01.86.2-1.01.4-1.41.9-0.3-0.41.52.50.6-1.11.60.5
Light reinforcement 22.53.28.01.41.8-1.82.82.00.8-0.91.72.21.4-0.82.5
Reaction time number correct0.30.41.20.40.6-0.60.30.61.1-0.40.50.90.6-0.40.7
Reaction time mean minus median0.50.61.50.2-1.21.2-1.10.21.0-0.3-0.9-0.8-0.3-0.3-0.5
Reaction time mean minus median AUC0.40.51.70.4-0.90.9-1.10.41.3-0.5-0.8-0.40.1-0.5-0.2
Reaction time num false alarms2.23.06.1-2.4-0.40.4-1.0-2.3-0.52.41.0-1.5-2.32.5-1.8
Reaction time num false alarms AUC1.62.24.7-2.1-0.10.1-0.7-2.0-0.12.11.1-1.1-1.92.2-1.4
Reaction time trials correct on left0.30.41.20.40.6-0.60.30.61.1-0.40.50.90.6-0.40.7
Reaction time trials on left0.30.41.40.40.6-0.60.30.61.2-0.40.51.00.6-0.40.7
Reaction time mean2.02.74.6-2.1-0.90.9-1.4-2.10.22.00.4-1.7-2.12.1-2.0
Reaction time mean AUC1.82.44.7-2.2-0.50.5-1.2-2.1-0.12.10.5-1.4-1.92.1-1.8
Median of all reaction times2.33.15.9-2.4-0.50.5-1.1-2.30.12.40.8-1.6-2.22.4-2.0
Reaction time omissions0.50.62.7-0.8-0.30.3-0.5-0.51.60.90.8-0.5-0.91.0-0.3
Reaction time false alarm rate1.72.44.9-2.1-0.40.4-0.6-2.0-0.42.10.9-1.4-2.12.2-1.5
Reaction time premature initiation rate1.11.53.90.6-2.02.0-1.20.3-0.3-0.7-1.9-1.6-0.5-0.8-0.7
Reaction time premature initiations0.50.81.70.8-1.31.3-0.70.60.7-0.9-1.3-0.7-0.0-0.9-0.1
Std. dev. reaction times1.52.13.9-1.2-1.71.7-2.0-1.30.30.9-1.0-2.0-1.40.9-1.8
Reaction time trials completed0.30.41.40.40.6-0.60.30.61.2-0.40.51.00.6-0.40.7
Reaction time trials AUC0.20.31.20.30.4-0.40.10.51.1-0.30.40.70.3-0.30.5
Social response proportion0.80.92.9-0.7-0.90.9-0.6-0.51.50.80.5-1.0-1.70.9-0.6
Social responses2.12.75.4-1.3-2.12.1-1.5-1.21.71.2-0.2-2.1-2.31.3-1.7
Social time0.81.02.9-1.30.7-0.70.8-0.70.21.41.70.3-1.01.5-0.3
Conditioned locomotion0.91.02.0-1.2-0.90.9-1.0-1.30.51.0-0.1-1.0-1.31.0-1.4
Cocaine response after cond. corrected0.80.92.1-1.20.2-0.20.1-0.8-0.21.41.0-0.6-1.51.5-0.6
Cocaine response after cond. not corrected0.30.41.2-0.30.8-0.80.90.10.20.51.10.3-0.30.60.5
Cocaine response before conditioning2.63.26.32.21.3-1.31.61.90.3-2.1-0.12.02.5-2.12.2
Saline control response1.52.06.20.6-2.02.0-2.20.0-0.1-1.0-2.5-1.30.4-1.1-1.0
Condit. Reinf. active minus inactive responses3.84.712.92.3-2.52.5-2.31.40.6-2.7-3.6-0.91.6-2.8-0.0
Condit. Reinf. active-inactive response ratio1.01.02.31.4-0.50.5-0.51.00.3-1.5-1.30.21.3-1.50.6
Condit. Reinf. active responses5.27.219.42.4-3.53.5-3.31.51.2-2.9-4.4-1.61.3-3.0-0.5
Condit. Reinf. inactive responses3.64.510.51.2-3.23.2-3.00.71.6-1.7-3.2-1.80.2-1.7-0.9
Condit. Reinf. lever presses8.311.521.94.1-3.23.2-2.93.12.6-4.6-4.7-0.43.0-4.71.0
Condit. Reinf. lever reinforcers received5.57.720.32.7-3.43.4-3.31.71.5-3.2-4.5-1.31.8-3.3-0.2
Pavlov. Cond. lever latency9.312.826.3-4.72.9-2.92.3-3.9-2.95.14.4-0.1-3.15.1-1.7
Pavlov. Cond. magazine entry latency4.34.910.13.1-0.40.40.23.22.9-3.0-0.91.42.0-3.02.4
Pavlov. Cond. change in total contacts8.612.125.74.7-2.42.4-1.94.02.8-5.0-4.00.63.5-5.12.0
Pavlov. Cond. index score7.910.421.34.3-2.32.3-1.73.83.2-4.6-3.50.52.9-4.61.9
Pavlov. Cond. latency score7.59.519.94.3-1.91.9-1.33.73.1-4.5-3.10.72.9-4.42.1
Pavlov. Cond. lever contacts9.513.226.74.7-3.03.0-2.63.93.0-5.1-4.60.13.3-5.21.6
Pavlov. Cond. magazine entry number5.77.014.5-3.80.8-0.80.2-3.6-2.73.81.9-1.4-2.83.8-2.4
Pavlov. Cond. intertrial magazine entries1.11.42.6-0.8-1.41.4-1.6-1.3-0.90.6-1.3-1.6-0.60.6-1.5
Pavlov. Cond. lever-magazine prob. diff.7.59.619.84.2-2.32.3-1.83.63.0-4.4-3.40.42.7-4.51.8
Pavlov. Cond. response bias10.314.229.45.0-2.82.8-2.24.33.4-5.4-4.40.43.5-5.42.0
Conditioned reinforcement - actives0.70.71.90.90.3-0.3-0.10.71.4-1.0-0.40.71.2-1.00.7
Conditioned reinforcement - inactives0.70.81.5-1.2-0.70.7-0.7-1.20.21.1-0.0-1.0-0.91.1-1.2
Conditioned locomotion1.92.24.01.90.5-0.50.31.71.8-1.9-0.41.52.0-1.91.7
Intermittent access intake day 1-15 change2.02.05.11.70.3-0.31.21.92.2-1.50.21.21.4-1.41.8
Intermittent access intake escalation2.22.16.31.60.4-0.41.21.92.5-1.50.31.31.5-1.41.8
Intermittent access intake escalation 20.40.43.10.4-0.10.10.60.61.8-0.20.40.00.0-0.10.6
Intermitt. access day 1 inactive lever presses1.31.43.3-1.7-0.40.4-0.8-1.80.71.60.4-1.1-1.11.7-1.4
Intermitt. access day 15 inactive lever presses0.20.30.80.5-0.10.10.50.60.9-0.6-0.30.50.6-0.60.3
Intermitt. access escalation Index0.10.10.2-0.2-0.40.4-0.4-0.20.30.0-0.4-0.4-0.10.1-0.4
Intermittent access day 1 total infusions0.50.62.30.4-0.90.9-1.10.00.1-0.8-1.5-0.50.6-0.8-0.5
Intermittent access day 15 total infusions0.91.04.01.0-0.60.6-0.30.92.0-1.2-0.90.21.1-1.20.5
Intermittent access terminal intake (last 3 days)0.70.82.90.8-0.80.8-0.50.61.7-1.0-1.1-0.10.9-1.00.1
Intermittent access total infusions0.50.51.40.5-0.70.7-0.80.31.2-0.8-1.1-0.20.7-0.8-0.1
Intermittent access day 1 locomotion0.10.10.5-0.20.1-0.1-0.3-0.50.1-0.0-0.40.10.7-0.0-0.3
Intermittent access day 15 total locomotion1.31.43.11.30.4-0.40.51.21.7-1.4-0.21.21.8-1.31.3
Intermittent access total locomotion0.50.51.70.8-0.40.4-0.40.61.3-0.9-0.70.31.0-0.90.4
Intermittent access standard deviation0.40.54.00.3-0.00.00.60.62.0-0.20.50.20.2-0.10.6
Cocaine induced anxiety2.02.35.4-2.30.5-0.5-0.0-2.0-0.82.31.4-0.6-1.62.3-1.4
Post-drug Anxiety1.61.83.2-1.6-0.70.7-1.0-1.6-1.71.5-0.3-1.4-1.31.4-1.8
Baseline Anxiety0.91.03.70.9-1.01.0-0.90.3-0.8-1.1-1.9-0.50.8-1.2-0.3
Lifetime Intake0.70.81.60.9-0.70.7-0.70.71.3-1.1-1.2-0.00.9-1.10.2
Incentive Sensitization - Responses1.01.02.30.3-1.31.3-1.5-0.11.4-0.6-1.5-0.80.3-0.6-0.6
Incentive Sensitization - Breakpoint0.80.82.60.4-1.11.1-1.20.11.6-0.7-1.2-0.60.5-0.7-0.3
Progressive ratio test 1 active lever presses0.00.00.20.10.0-0.00.30.0-0.4-0.1-0.20.10.4-0.10.0
Progressive ratio test 1 breakpoint0.00.00.20.0-0.10.10.0-0.1-0.5-0.1-0.3-0.00.3-0.1-0.1
Progressive ratio test 1 inactive lever presses0.20.21.10.1-0.30.3-0.5-0.21.1-0.2-0.4-0.10.4-0.2-0.1
Progressive ratio test 2 active lever presses0.40.41.20.1-0.80.8-0.9-0.30.8-0.4-1.1-0.50.6-0.3-0.5
Progressive ratio test 2 breakpoint0.40.51.40.1-0.90.9-1.0-0.30.8-0.4-1.2-0.60.6-0.4-0.5
Progressive ratio test 2 inactive lever presses0.40.43.00.4-0.30.3-0.30.21.7-0.6-0.50.30.8-0.50.1
Total sessions with >9 infusions2.72.96.22.40.0-0.00.32.21.2-2.5-1.11.32.2-2.51.7
Short access day 1 total inactive lever presses0.40.51.5-1.1-0.20.2-0.7-1.20.50.8-0.0-0.4-0.10.9-0.9
Short access day 10 total inactive lever presses0.40.40.9-0.90.4-0.40.3-0.80.90.90.9-0.1-0.51.0-0.3
Short access day 1 total infusions1.01.12.61.0-1.01.0-1.20.70.9-1.3-1.6-0.30.8-1.30.0
Short access day 10 total infusions0.80.92.20.9-1.01.0-1.00.60.9-1.2-1.5-0.30.9-1.20.0
Short access total infusions0.70.81.71.0-0.80.8-0.70.90.6-1.2-1.3-0.10.8-1.20.2
Short access day 1 locomotion1.92.04.41.51.2-1.21.11.30.8-1.50.11.82.1-1.51.7
Short access day 10 total locomotion0.70.76.60.5-0.60.6-0.30.62.6-0.50.00.00.3-0.30.4
Short access total locomotion0.30.31.10.50.2-0.20.10.51.0-0.50.00.60.9-0.50.6
Compulsive drug intake0.80.82.4-0.11.5-1.51.4-0.1-0.60.31.11.00.40.30.6
One hour access (0.3 mA shock)1.01.26.01.2-0.70.7-0.71.12.5-1.3-0.8-0.00.7-1.20.6
One hour access (shock baseline)1.21.44.30.8-1.61.6-1.50.72.1-1.0-1.4-0.70.3-1.0-0.2
Number of responses in last shaping day0.60.61.4-0.7-0.80.8-0.8-1.1-0.40.5-0.8-1.0-0.50.4-1.2
Context. condit. distance diff. score1.92.35.72.2-0.30.30.12.00.2-2.3-1.40.91.7-2.41.2
Locomotion velocity, session 11.21.33.00.51.6-1.61.70.60.5-0.31.41.50.8-0.21.4
Locomotion distance, session 11.31.72.61.60.5-0.50.91.61.6-1.50.01.31.6-1.51.6
Locomotion velocity, session 20.60.72.61.00.2-0.20.40.91.6-0.80.30.70.6-0.71.1
Locomotion distance, session 20.91.26.31.3-0.20.20.41.42.5-1.20.20.70.5-1.11.2
Locomotion velocity, session 30.50.51.50.90.2-0.20.20.7-0.3-1.0-0.70.71.2-1.10.5
Locomotion distance, session 31.31.44.01.40.8-0.80.71.3-0.5-1.4-0.51.42.0-1.51.2
Stereotopy head waving bouts, day 30.70.81.4-0.8-1.11.1-0.8-0.9-0.00.7-0.4-1.2-1.20.7-1.1
Stereotopy head waving duration, day 30.10.20.40.5-0.10.10.40.50.6-0.5-0.00.40.3-0.50.5
Locomotion velocity, session 70.40.41.40.30.8-0.81.20.5-0.0-0.10.80.70.2-0.10.8
Locomotion distance, session 70.20.30.9-0.6-0.10.1-0.2-0.7-0.30.70.3-0.5-0.90.7-0.6
Stereotopy head waving bouts, day 72.12.46.22.0-0.00.00.21.7-0.1-2.2-1.51.12.5-2.31.2
Stereotopy head waving duration, day 72.32.86.92.3-0.10.10.21.90.4-2.4-1.51.12.6-2.51.4
Locomotion velocity, session 80.70.82.01.2-0.50.5-0.40.8-0.2-1.4-1.20.31.1-1.40.4
Locomotion distance, session 81.92.96.12.4-0.80.8-0.22.22.0-2.5-1.30.81.6-2.51.4
Degree of sensitization distance3.03.06.7-1.4-2.02.0-1.9-1.50.61.3-0.5-2.3-2.61.4-1.9
Degree of sensitization stereotypy3.94.310.12.8-0.20.20.02.3-0.1-3.0-2.11.43.2-3.11.6
Condit. Reinf. active minus inactive responses0.80.91.8-0.3-1.21.2-1.3-0.3-0.80.1-1.3-1.2-0.5-0.0-1.1
Condit. Reinf. active-inactive response ratio1.21.33.1-0.3-1.31.3-1.6-0.7-1.50.0-1.8-1.4-0.3-0.1-1.4
Condit. Reinf. active responses0.70.91.7-0.8-1.11.1-1.3-0.80.10.6-0.8-1.2-0.80.5-1.3
Condit. Reinf. inactive responses0.30.42.5-0.5-0.20.2-0.2-0.41.60.50.6-0.2-0.60.6-0.2
Incentive salience index mean0.60.71.9-0.4-1.11.1-1.4-0.50.20.2-1.0-1.1-0.40.2-1.0
Condit. Reinf. lever presses0.10.11.1-0.1-0.10.1-0.4-0.21.1-0.0-0.1-0.00.40.1-0.0
Time in familiar zone, hab. session 10.10.10.20.3-0.50.5-0.30.3-0.3-0.3-0.4-0.30.0-0.40.0
Time in novel zone, hab. session 10.40.41.2-0.80.2-0.2-0.0-0.8-1.10.80.2-0.4-0.70.8-0.6
Total zone transitions, hab. session 10.71.02.41.00.9-0.90.91.0-0.0-0.90.11.31.6-1.01.2
Total locomotion distance, hab. session 11.42.04.3-1.2-1.51.5-1.5-1.1-0.51.2-0.5-1.9-2.11.1-1.6
Locomotion velocity, hab. session 11.11.63.4-1.0-1.51.5-1.5-1.00.31.0-0.4-1.7-1.91.0-1.4
Time in familiar zone, hab. session 21.11.13.50.6-1.21.2-1.30.2-1.1-0.9-1.9-0.9-0.1-1.0-0.7
Time in novel zone, hab. session 21.21.23.70.21.1-1.11.40.61.90.11.71.20.30.31.3
Total zone transitions, hab. session 21.92.55.22.2-0.10.10.22.10.9-2.2-1.01.32.1-2.31.5
Total locomotion distance, hab. session 22.02.66.8-0.3-2.62.6-2.3-0.20.90.2-1.3-2.1-1.90.1-1.4
Locomotion velocity, hab. session 22.22.97.4-0.4-2.72.7-2.4-0.40.90.3-1.3-2.2-2.00.3-1.6
Novel to familiar place preference ratio1.61.63.9-1.1-1.61.6-2.0-1.40.10.7-1.0-1.4-1.00.7-1.8
Novelty place preference1.51.63.7-1.0-1.61.6-1.9-1.30.10.6-1.1-1.4-0.90.6-1.7
Time in novel zone, NPP test1.61.64.0-0.9-1.71.7-2.0-1.20.10.5-1.2-1.4-0.90.4-1.7
Total zone transitions, NPP test1.31.84.01.40.8-0.81.01.62.0-1.30.61.51.5-1.11.8
Total locomotion distance, NPP test0.81.14.0-0.4-1.31.3-0.70.12.00.50.4-1.2-1.90.7-0.4
Locomotion velocity, NPP test0.71.03.6-0.5-1.01.0-0.50.11.90.70.7-1.0-1.90.9-0.3
Pavlov. Cond. lever latency0.40.51.6-0.50.8-0.81.00.0-0.60.71.30.3-0.80.80.2
Pavlov. Cond. magazine entry latency1.51.94.11.7-1.41.4-1.01.31.0-1.9-2.0-0.31.0-1.90.3
Pavlov. Cond. change in total contacts0.70.72.80.4-0.90.9-1.2-0.3-0.5-0.7-1.7-0.60.7-0.7-0.6
Pavlov. Cond. index score1.21.53.81.4-1.21.2-1.10.80.8-1.6-1.9-0.31.2-1.60.2
Pavlov. Cond. latency score1.11.43.71.2-1.21.2-1.20.60.9-1.5-1.9-0.41.1-1.50.0
Pavlov. Cond. lever contacts0.40.41.50.6-0.70.7-0.70.10.4-0.8-1.2-0.30.7-0.8-0.1
Pavlov. Cond. magazine entry number1.51.94.0-1.70.9-0.90.8-1.2-0.92.01.9-0.1-1.62.0-0.6
Pavlov. Cond. intertrial magazine entries0.40.51.2-1.10.4-0.40.2-0.9-0.61.10.7-0.1-0.51.1-0.6
Pavlov. Cond. lever-magazine prob. diff.0.91.23.01.3-0.90.9-0.90.70.6-1.5-1.7-0.11.3-1.50.2
Pavlov. Cond. response bias0.50.61.60.9-0.80.8-0.60.50.6-1.0-1.3-0.30.7-1.00.1
Bone: apparent density0.20.41.0-0.11.0-1.00.9-0.3-0.70.10.50.80.60.10.3
Bone surface0.20.41.60.5-0.40.4-0.6-0.0-0.7-0.8-1.3-0.11.0-0.8-0.2
Bone volume0.10.21.00.2-0.50.5-0.6-0.2-0.3-0.4-1.0-0.30.5-0.5-0.4
Bone: connectivity density1.32.14.20.92.0-2.02.00.8-0.4-0.71.01.91.7-0.61.7
Bone: cortical apparent density1.62.15.1-1.9-0.70.7-0.8-1.7-0.31.90.6-1.5-2.31.9-1.6
Bone: cortical area0.71.02.6-0.0-1.61.6-1.5-0.21.0-0.2-1.2-1.1-0.5-0.2-0.8
Bone: cortical porosity0.20.21.00.20.5-0.5-0.0-0.2-0.4-0.5-0.50.61.0-0.50.1
Bone: cortical porosity0.20.20.80.20.4-0.4-0.1-0.2-0.3-0.4-0.50.50.9-0.4-0.0
Bone: cortical thickness0.20.32.2-0.1-0.10.10.20.01.50.20.70.1-0.50.30.2
Bone: cortical thickness0.10.21.1-0.0-0.50.5-0.40.11.1-0.1-0.2-0.2-0.3-0.1-0.2
Bone: cortical tissue density1.62.15.1-1.8-0.60.6-0.7-1.7-0.41.90.6-1.4-2.31.9-1.5
Bone: elastic displacement1.31.54.0-0.41.8-1.81.9-0.0-0.10.72.01.30.10.80.9
Bone: elastic work2.53.38.6-0.12.7-2.72.90.40.00.52.72.10.50.61.8
Bone: endosteal estimation0.91.95.60.2-1.91.9-2.1-0.2-0.8-0.6-2.4-1.60.1-0.7-1.2
Bone: endosteal perimeter1.02.06.10.7-2.02.0-2.00.2-0.1-1.0-2.5-1.30.5-1.1-0.8
Bone: final force1.11.83.8-1.5-1.21.2-1.6-1.7-0.41.2-0.6-1.5-1.41.2-2.0
Bone: final moment0.91.53.1-1.2-1.31.3-1.6-1.4-0.20.9-0.8-1.4-1.20.9-1.8
Bone: marrow area0.81.74.90.1-1.81.8-2.0-0.3-0.9-0.4-2.2-1.6-0.1-0.5-1.3
Bone: maximum diameter1.12.16.00.9-2.12.1-2.00.40.2-1.2-2.5-1.20.5-1.3-0.7
Bone: maximum force0.50.91.9-0.9-0.90.9-1.3-1.3-0.60.7-0.7-1.1-0.70.6-1.4
Bone: maximum moment0.30.61.3-0.6-0.90.9-1.2-0.9-0.20.3-0.8-0.9-0.40.3-1.1
Bone: minimum diameter1.63.07.0-0.5-2.62.6-2.6-0.90.10.2-2.0-2.3-1.10.2-1.8
Bone: periosteal estimation0.81.64.10.2-1.91.9-2.0-0.20.1-0.5-2.0-1.4-0.0-0.6-1.0
Bone: periosteal perimeter0.91.43.50.7-1.81.8-1.70.40.8-0.9-1.9-1.00.3-0.9-0.5
Bone: post-yield work0.10.10.30.3-0.40.4-0.30.2-0.5-0.3-0.5-0.2-0.1-0.4-0.1
Bone: stiffness2.53.97.5-2.1-1.71.7-2.4-2.4-1.01.8-0.9-2.3-2.01.7-2.7
Bone: tissue strength2.12.04.20.81.8-1.82.10.90.6-0.51.52.01.2-0.51.8
Bone: trabecular number0.71.22.9-0.31.7-1.71.6-0.2-0.40.51.51.30.60.50.8
Bone: trabecular spacing1.01.34.01.50.0-0.00.31.52.0-1.4-0.10.80.9-1.31.4
Bone: trabecular thickness1.51.83.8-1.4-1.11.1-1.5-1.6-1.41.1-0.8-1.5-1.01.0-2.0
Bone: trabecular tissue density5.17.112.5-2.9-2.42.4-2.9-3.1-1.02.6-0.9-3.3-3.12.5-3.5
Breakpoint value in progressive ratio session0.30.30.60.40.6-0.60.60.60.7-0.20.70.80.3-0.20.8
Distance traveled before self-admin0.50.51.6-0.60.3-0.31.0-0.0-0.40.91.2-0.1-1.30.90.0
Distance traveled after self-admin0.50.51.50.80.5-0.5-0.01.20.1-0.60.41.10.7-0.70.9
Delta time in closed arm before/after self-admin2.72.67.4-1.7-1.21.2-0.1-1.5-1.01.80.0-2.2-2.71.8-1.9
Delta time in open arm before/after self-admin1.31.23.51.1-0.90.9-1.50.40.1-1.4-1.9-0.11.4-1.4-0.0
Diff in mean of infusions in LGA sessions1.82.14.1-2.0-0.00.0-0.8-2.0-1.91.90.3-1.0-1.11.9-1.6
Extinction: sum of active levers before priming0.00.00.3-0.20.1-0.1-0.1-0.10.50.20.30.0-0.10.30.0
Active lever presses in extinction session 62.42.34.11.80.7-0.70.71.91.2-1.8-0.11.82.0-1.81.7
Delta distance traveled before/after self-admin1.41.55.51.0-0.90.9-2.30.6-0.1-1.4-1.90.11.5-1.5-0.2
Delta ambulatory time before/after self-admin1.11.23.21.2-0.30.3-1.50.8-0.0-1.5-1.50.61.8-1.60.3
Time in closed arm before self-admin2.42.75.12.20.3-0.30.82.11.3-2.2-0.61.72.1-2.31.7
Time in closed arm after self-admin0.60.62.7-0.70.6-0.61.6-0.5-0.60.80.80.1-0.70.7-0.3
Time in open arm before self-admin2.72.96.7-2.21.2-1.20.9-1.6-0.62.52.4-0.4-2.12.6-0.6
Time in open arm after self-admin0.30.31.3-0.4-0.50.5-1.1-0.5-0.30.3-0.4-0.8-0.50.4-0.6
Sum of active levers in priming session hrs 5-60.20.20.60.5-0.30.3-0.80.70.7-0.40.10.40.2-0.40.4
Time to tail flick, vehicle, before self-admin0.20.20.50.5-0.40.4-0.60.60.5-0.5-0.40.20.7-0.50.2
Time to tail flick, vehicle, after self-admin1.41.55.31.40.2-0.2-0.41.00.1-1.7-1.31.02.3-1.80.8
Time to tail flick, test, before self-admin0.90.92.40.7-0.90.9-1.50.2-1.0-0.9-1.5-0.40.8-0.9-0.2
Time to tail flick, test, after self-admin1.91.95.0-0.1-1.91.9-2.2-0.4-1.0-0.2-2.0-1.7-0.5-0.3-1.4
Delta time to tail flick, vehicle, before/after SA0.80.82.40.90.9-0.90.70.5-0.0-1.0-0.40.91.6-1.00.8
Delta time to tail flick, test, before/after SA0.20.20.6-0.4-0.10.20.1-0.10.40.50.3-0.5-0.80.5-0.3
Ambulatory time before self-admin0.60.61.6-0.70.6-0.61.1-0.2-0.70.91.30.1-1.00.90.1
Ambulatory time after self-admin0.50.51.30.80.5-0.50.21.0-0.6-0.80.01.10.9-0.90.7
Total heroin consumption0.70.82.61.1-0.70.7-0.21.21.6-1.1-0.50.30.4-1.10.6
Area under the delay curve0.40.51.3-1.0-0.10.10.2-1.2-0.00.90.2-0.6-0.60.9-0.8
Delay disc. indifference point, 0s delay0.50.62.40.5-1.01.0-0.50.41.5-0.7-0.8-0.40.1-0.6-0.0
Delay disc. indifference point, 16s delay0.80.82.0-1.3-0.10.1-0.2-1.4-0.71.1-0.0-0.7-0.91.1-1.3
Delay disc. indifference point, 2s delay0.50.51.5-0.0-1.11.1-0.8-0.40.4-0.2-1.2-0.80.3-0.2-0.7
Delay disc. indifference point, 24s delay1.31.32.9-1.70.0-0.0-0.2-1.5-0.21.70.7-0.8-1.41.7-1.3
Delay disc. indifference point, 4s delay1.01.12.80.0-1.71.7-1.5-0.30.7-0.2-1.4-1.3-0.4-0.2-0.9
Delay disc. indifference point, 8s delay0.20.20.4-0.60.2-0.20.7-0.60.30.50.3-0.2-0.20.6-0.3
Delay discount exponential model param0.40.41.21.0-0.10.1-0.31.1-0.1-0.9-0.30.50.5-1.00.7
Delay discount hyperbolic model param0.30.41.00.90.2-0.2-0.11.0-0.2-0.8-0.00.60.5-0.80.7
Fecal boli incidents, locomotor time 10.60.61.4-0.91.2-1.20.7-1.10.60.80.80.40.20.8-0.2
Change in fecal boli incidents, locomotor task0.40.43.5-0.1-0.00.00.50.1-1.90.2-0.0-0.3-0.70.1-0.2
Time >=10cm from walls, locomotor time 10.20.20.60.5-0.20.2-0.00.10.1-0.7-0.80.10.5-0.7-0.0
Bouts of movement, locomotor time 10.20.30.7-0.4-0.50.5-0.9-0.7-0.30.2-0.6-0.40.10.2-0.7
Total resting periods, locomotor time 10.10.10.3-0.40.2-0.2-0.2-0.6-0.10.30.00.20.30.2-0.3
Rest time, locomotor task time 10.20.22.0-0.30.3-0.3-0.0-0.5-1.40.2-0.30.10.20.1-0.5
Distance moved, locomotor task time 10.20.20.80.2-0.70.7-0.70.30.9-0.1-0.1-0.5-0.30.00.0
Vertical activity count, locomotor time 10.60.62.0-0.3-1.01.0-1.4-0.31.40.2-0.4-0.9-0.60.3-0.6
Time >=10cm from walls, locomotor time 21.41.54.60.4-1.81.8-1.70.0-0.2-0.7-2.1-1.2-0.3-0.9-1.1
Bouts of movement, locomotor time 22.62.85.4-1.4-1.91.9-1.6-1.7-0.71.1-1.4-2.3-1.81.0-2.3
Total resting periods, locomotor time 22.22.44.7-1.5-1.61.6-1.2-1.8-0.61.3-0.9-2.1-1.81.2-2.2
Rest time, locomotor task time 21.21.43.0-1.41.0-1.01.3-0.9-0.61.61.70.2-1.21.6-0.3
Distance moved, locomotor task time 21.92.25.81.4-1.71.7-2.41.11.4-1.6-1.9-0.60.9-1.60.1
Vertical activity count, locomotor time 21.41.56.0-0.3-1.71.6-2.4-0.50.70.0-1.4-1.4-0.70.0-1.2
Weight adjusted by age0.40.51.10.6-0.90.9-0.40.5-0.9-0.6-1.0-0.7-0.3-0.6-0.2
Seeking ratio, delayed vs. immediate footshock1.01.23.5-0.61.9-1.90.4-0.5-0.60.81.71.00.30.90.6
Locomotion in novel chamber1.11.43.70.61.4-1.41.30.81.9-0.41.41.40.6-0.31.4
Locomotion in novel chamber post-restriction1.61.95.01.60.7-0.70.91.31.1-1.7-0.41.52.2-1.61.5
Progressive ratio0.60.71.70.70.9-0.91.30.90.3-0.60.51.11.0-0.51.1
Food seeking constrained by brief footshock1.01.22.90.7-1.61.6-1.60.60.1-0.9-1.7-0.90.1-1.0-0.4
Seeking ratio, punishment vs. effort1.41.85.8-0.0-2.02.0-2.4-0.40.2-0.2-1.6-1.7-0.9-0.2-1.2
Run reversals in cocaine runway, females1.11.03.0-0.1-1.71.7-0.7-0.0-0.10.2-0.8-1.7-1.40.2-0.7
Run reversals in cocaine runway, males0.40.42.2-0.50.7-0.71.5-0.6-0.20.50.50.30.20.5-0.0
Latency to leave start box in cocaine runway0.91.03.2-1.20.4-0.41.1-0.9-1.81.30.7-0.5-0.91.3-0.6
Latency to leave start box in cocaine runway, F1.11.22.5-1.4-0.30.3-0.0-1.3-1.61.40.2-1.2-1.21.4-1.2
Latency to leave start box in cocaine runway, M0.80.82.3-0.21.4-1.41.5-0.1-0.60.31.10.90.30.40.6
Cd content in liver0.30.30.8-0.80.3-0.3-0.1-0.7-0.80.90.4-0.4-0.50.9-0.4
Co content in liver1.82.15.7-0.0-2.02.0-2.4-0.6-0.7-0.4-2.4-1.6-0.1-0.5-1.5
Cu content in liver1.01.23.3-0.0-1.41.4-1.8-0.4-0.8-0.3-1.8-1.2-0.0-0.3-1.1
Fe content in liver0.40.41.3-0.7-0.30.3-0.6-1.2-0.90.6-0.4-0.6-0.20.5-0.9
K content in liver0.80.83.8-0.8-0.70.7-0.8-0.52.00.80.4-0.8-1.00.9-0.6
Mg content in liver0.30.32.60.3-0.40.4-0.30.41.6-0.3-0.0-0.00.1-0.20.2
Mn content in liver1.21.43.8-0.61.7-1.71.70.00.20.82.01.1-0.10.90.7
Na content in liver0.30.41.60.70.2-0.20.30.30.2-0.7-0.40.61.3-0.70.5
Rb content in liver0.30.41.30.4-0.50.5-0.9-0.00.2-0.6-1.2-0.21.0-0.6-0.2
Se content in liver1.82.24.5-1.91.5-1.51.0-1.6-0.92.12.00.3-0.82.1-0.5
Sr content in liver1.91.73.31.41.2-1.21.81.60.4-1.10.81.51.0-1.11.8
Zn content in liver2.32.55.32.2-0.50.5-0.12.02.1-2.3-1.20.61.5-2.31.4