Best TWAS P=2.480881e-15 · Best GWAS P=0.0693673 conditioned to 9.226924e-11
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Eral1 | gene expression | ENSRNOG00000010673 | 0.04 | 0.01 | enet | 183 | 0.02 | 0.00088 | 0.61 | 7.9 | 2.5e-15 | 0.76 | 0.05 | 0.05 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.