Hub : Genes

Znf624l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA NM_001408870.1 0.02 0.02 1.9e-03 0.02 0.02 0.01 0.02 2.1e-03 2.3e-03 1.6e-02 2.8e-03
2 pVTA gene expression Znf624l 0.21 0.12 4.9e-08 0.19 0.17 0.19 0.2 1.4e-08 4.8e-08 1.3e-08 6.7e-09
3 Liver intron excision ratio chr7_7856802_7875052 0.04 0.03 3.4e-05 0.04 0.04 0.04 0.04 3.9e-05 5.0e-05 7.3e-05 4.3e-05
4 Liver intron excision ratio chr7_7856802_7890874 0.05 0.04 8.0e-06 0.04 0.04 0.04 0.04 1.6e-05 2.8e-05 2.4e-05 1.9e-05
5 Adipose gene expression Znf624l 0.27 0.13 0.0e+00 0.22 0.22 0.22 0.22 6.2e-24 6.3e-24 6.3e-24 2.6e-24
6 PL gene expression Znf624l 0.3 0.14 0.0e+00 0.34 0.33 0.34 0.34 1.3e-38 2.1e-37 2.4e-38 2.1e-38
7 Brain intron excision ratio chr7_7856802_7890874 0.03 0.03 2.1e-03 0.02 0.02 0.02 0.01 1.1e-02 1.2e-02 1.1e-02 1.4e-02
8 IL gene expression Znf624l 0.32 0.17 6.4e-06 0.17 0.15 0.18 0.17 6.3e-05 1.9e-04 5.1e-05 5.9e-05
9 Adipose intron excision ratio chr7_7856802_7875052 0.04 0.03 4.6e-05 0.03 0.03 0.03 0.03 9.3e-05 1.9e-04 2.8e-04 1.6e-04
10 Adipose intron excision ratio chr7_7856802_7890874 0.05 0.03 2.7e-05 0.04 0.03 0.03 0.03 6.2e-05 1.5e-04 2.8e-04 1.0e-04
11 Liver gene expression Znf624l 0.29 0.16 0.0e+00 0.24 0.23 0.23 0.24 2.9e-26 8.0e-26 1.0e-25 1.5e-26
12 BLA isoform ratio NM_001408870.1 0.04 0.03 8.0e-03 0.03 0.03 0.02 0.02 1.3e-02 1.5e-02 3.6e-02 2.4e-02
13 NAcc gene expression Znf624l 0.27 0.13 0.0e+00 0.3 0.28 0.29 0.29 8.7e-35 1.1e-32 1.0e-33 7.5e-34
14 NAcc isoform ratio NM_001408870.1 0.05 0.04 7.6e-07 0.05 0.05 0.05 0.05 1.1e-06 2.0e-06 2.8e-06 2.5e-06
15 OFC gene expression Znf624l 0.16 0.11 6.3e-04 0.14 0.14 0.15 0.13 3.9e-04 3.5e-04 2.4e-04 6.2e-04
16 BLA gene expression Znf624l 0.31 0.16 1.7e-16 0.32 0.31 0.32 0.31 1.2e-17 6.0e-17 7.5e-18 2.5e-17
17 LHb gene expression Znf624l 0.28 0.16 2.4e-05 0.18 0.2 0.18 0.18 3.6e-05 2.1e-05 4.9e-05 4.0e-05
18 Brain gene expression Znf624l 0.23 0.13 0.0e+00 0.17 0.17 0.17 0.17 1.2e-15 8.2e-16 8.2e-16 5.2e-16
19 Adipose mRNA stability Znf624l 0.06 0.04 3.2e-06 0.04 0.03 0.03 0.03 1.6e-05 1.2e-04 2.6e-04 1.1e-04
20 Brain mRNA stability Znf624l 0.05 0.04 3.8e-03 0.03 0.01 0.01 0.02 1.1e-03 3.0e-02 1.4e-02 6.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.11.87.61.21.2-1.21.21.2-1.21.2-1.2-1.21.21.21.2-1.21.2-0.6-1.41.81.60.52.8
Area under the delay curve1.41.42.5-1.2-1.21.2-1.2-1.21.2-1.21.21.3-1.3-1.2-1.21.2-1.21.31.1-0.8-1.21.60.3
BMI with tail6.019.622.5-4.5-4.54.6-4.6-4.64.6-4.54.64.7-4.7-4.6-4.64.6-4.64.74.3-3.9-4.24.6-0.8
BMI without tail2.65.46.7-2.4-2.42.4-2.4-2.42.4-2.42.42.4-2.4-2.6-2.42.4-2.42.42.3-2.3-2.42.0-1.0
Body weight1.25.15.7-2.4-2.42.4-2.4-2.42.4-2.32.42.3-2.3-2.3-2.32.3-2.32.42.2-2.1-2.32.2-0.6
Weight adjusted by age0.40.50.9-0.7-0.70.7-0.7-0.70.7-0.70.80.7-0.7-1.0-0.70.7-0.70.70.5-0.9-0.80.4-0.2
Bone surface3.05.415.12.22.2-2.22.22.2-2.22.2-2.2-2.22.22.22.2-2.22.2-1.4-2.53.02.60.23.9
Bone volume3.15.414.52.32.3-2.32.32.3-2.32.3-2.3-2.22.22.22.2-2.22.2-1.4-2.43.02.60.23.8
Breakpoint value in progressive ratio session3.63.96.42.02.0-2.02.02.0-2.02.0-2.0-2.12.12.12.0-2.02.0-2.3-1.71.52.0-2.5-0.9
Number of licking bursts0.50.61.2-0.9-0.90.8-0.8-0.80.8-0.80.80.8-0.8-0.7-0.80.8-0.80.50.8-1.1-0.30.0-1.0
Context. condit. distance diff. score0.40.50.9-0.7-0.70.7-0.7-0.70.7-0.70.70.6-0.6-0.7-0.60.6-0.60.70.6-0.6-0.90.7-0.1
Locomotion velocity, session 11.51.62.31.31.3-1.31.31.3-1.31.3-1.3-1.31.31.31.3-1.31.3-1.1-1.51.50.5-0.61.5
Locomotion distance, session 10.81.13.51.01.0-1.01.01.0-1.01.0-1.0-0.90.91.00.9-0.90.9-0.6-1.21.40.30.01.9
Locomotion velocity, session 25.66.67.92.72.7-2.72.72.7-2.72.7-2.7-2.62.62.62.6-2.62.6-2.4-2.72.82.2-1.72.1
Locomotion distance, session 23.04.25.82.12.1-2.12.12.1-2.12.1-2.1-2.02.02.12.0-2.02.0-1.8-2.32.41.3-1.02.3
Locomotion velocity, session 35.26.17.62.52.5-2.52.52.5-2.52.5-2.5-2.62.62.62.6-2.62.6-2.7-2.42.12.4-2.80.3
Locomotion distance, session 30.00.00.00.00.0-0.00.00.0-0.00.0-0.0-0.00.00.00.0-0.00.0-0.1-0.1-0.1-0.0-0.20.0
Stereotopy head waving bouts, day 35.05.96.42.52.5-2.52.52.5-2.52.5-2.5-2.52.52.52.5-2.52.5-2.5-2.42.32.4-2.20.9
Stereotopy head waving duration, day 35.46.47.12.62.6-2.62.62.6-2.62.6-2.6-2.62.62.62.6-2.62.6-2.7-2.52.42.4-2.50.7
Locomotion velocity, session 71.01.11.51.11.1-1.11.11.1-1.11.1-1.1-1.01.01.11.0-1.01.0-1.0-1.11.11.2-0.90.8
Locomotion distance, session 70.20.30.5-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.50.5-0.50.30.5-0.7-0.40.0-0.6
Stereotopy head waving bouts, day 70.30.41.70.50.5-0.50.50.5-0.50.5-0.5-0.60.60.60.6-0.60.6-0.2-0.70.90.20.31.3
Stereotopy head waving duration, day 70.80.92.10.90.9-0.90.90.9-0.90.9-0.9-1.01.01.01.0-1.01.0-0.6-1.11.30.7-0.01.5
Locomotion velocity, session 81.61.94.61.41.4-1.41.41.4-1.41.4-1.4-1.41.41.41.4-1.41.4-1.0-1.61.80.9-0.22.1
Locomotion distance, session 80.20.30.90.60.6-0.60.60.6-0.60.6-0.6-0.50.50.50.5-0.50.5-0.4-0.70.70.0-0.20.9
Degree of sensitization distance0.30.30.5-0.6-0.60.6-0.6-0.60.6-0.60.60.6-0.6-0.6-0.60.6-0.60.70.6-0.5-0.50.7-0.1
Degree of sensitization stereotypy0.80.92.7-0.9-0.90.9-0.9-0.90.9-0.90.90.9-0.9-0.9-0.90.9-0.91.20.7-0.4-1.11.60.9
Conditioned locomotion3.13.64.4-1.9-1.92.0-2.0-2.02.0-2.02.02.0-2.0-2.0-2.02.0-2.01.72.0-2.1-1.71.1-1.5
Cocaine response after cond. corrected7.18.09.8-2.9-2.92.9-2.9-2.92.9-2.92.92.9-2.9-2.9-3.03.0-3.02.72.8-2.9-3.12.1-1.2
Cocaine response after cond. not corrected7.98.710.2-3.0-3.03.1-3.1-3.13.1-3.13.13.1-3.1-3.0-3.13.1-3.12.82.9-3.1-3.22.1-1.4
Cocaine response before conditioning0.70.81.31.01.0-0.90.90.9-0.90.9-0.9-1.01.01.00.9-0.90.9-0.9-0.70.91.1-0.7-0.0
Saline control response0.10.20.7-0.3-0.30.4-0.4-0.40.4-0.40.40.5-0.5-0.4-0.40.4-0.40.30.6-0.5-0.50.1-0.9
Bone: connectivity density0.40.65.00.50.5-0.50.50.5-0.50.5-0.6-0.50.50.50.5-0.50.5-0.1-0.81.10.80.82.2
Bone: cortical apparent density1.01.41.8-1.2-1.21.2-1.2-1.21.2-1.21.21.1-1.1-1.1-1.11.1-1.11.31.2-1.1-1.31.3-0.4
Bone: cortical area0.10.22.4-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.1-0.10.1-0.10.5-0.10.30.21.21.6
Bone: cortical porosity0.91.01.31.01.0-1.01.01.0-1.01.0-1.0-1.01.01.01.0-1.01.0-0.9-1.11.01.2-0.61.0
Bone: cortical porosity0.40.51.70.60.6-0.60.60.6-0.60.6-0.6-0.60.60.60.6-0.60.6-0.4-0.80.80.80.11.3
Bone: cortical thickness0.60.92.3-0.9-0.90.9-0.9-0.90.9-0.91.01.0-1.0-1.0-1.01.0-1.01.20.8-0.7-0.81.50.6
Bone: cortical thickness0.10.10.6-0.2-0.20.2-0.2-0.20.2-0.20.20.3-0.3-0.3-0.30.3-0.30.00.3-0.5-0.3-0.3-0.8
Bone: cortical tissue density0.81.01.5-1.1-1.11.1-1.1-1.11.1-1.11.10.9-0.9-1.0-1.01.0-1.01.11.0-1.0-1.21.1-0.4
Condit. Reinf. active minus inactive responses4.04.55.32.22.2-2.22.22.2-2.22.2-2.2-2.12.12.22.1-2.12.1-2.3-2.21.91.9-2.20.8
Condit. Reinf. active-inactive response ratio1.41.53.01.31.3-1.31.31.3-1.31.3-1.2-1.21.21.21.2-1.21.2-1.5-1.20.81.2-1.7-0.2
Condit. Reinf. active responses4.65.66.42.52.5-2.52.52.5-2.52.5-2.5-2.32.32.42.4-2.42.4-2.4-2.52.42.2-2.01.6
Condit. Reinf. inactive responses1.82.12.71.51.5-1.51.51.5-1.51.5-1.5-1.31.31.41.4-1.41.4-1.3-1.61.71.4-0.71.6
Incentive salience index mean3.03.64.42.02.0-2.02.02.0-2.02.0-2.0-1.91.91.91.9-1.91.9-1.9-2.11.91.7-1.51.5
Condit. Reinf. lever presses0.91.25.51.01.0-1.01.01.0-1.01.0-1.0-0.90.91.00.9-0.90.9-0.6-1.31.40.80.22.3
Condit. Reinf. active minus inactive responses1.31.63.81.21.2-1.21.21.2-1.21.2-1.2-1.21.21.21.2-1.21.2-1.6-1.00.81.5-1.9-0.8
Condit. Reinf. active-inactive response ratio0.30.32.3-0.4-0.40.4-0.4-0.40.4-0.40.40.4-0.4-0.4-0.40.4-0.4-0.00.5-0.8-0.2-0.7-1.5
Condit. Reinf. active responses2.02.83.91.71.7-1.71.71.7-1.71.7-1.7-1.71.71.71.7-1.71.7-1.9-1.61.42.0-1.90.1
Condit. Reinf. inactive responses1.82.22.71.61.6-1.61.61.6-1.61.6-1.6-1.51.51.61.5-1.51.5-1.5-1.51.51.6-1.10.8
Condit. Reinf. lever presses1.62.14.01.51.5-1.41.41.4-1.41.4-1.5-1.41.41.41.4-1.41.4-1.8-1.11.01.6-2.0-1.1
Condit. Reinf. lever reinforcers received1.41.93.21.41.4-1.41.41.4-1.41.4-1.4-1.31.31.41.3-1.31.3-1.6-1.21.01.7-1.8-0.3
Conditioned reinforcement - actives2.82.83.11.71.7-1.71.71.7-1.71.7-1.7-1.71.71.61.7-1.71.7-1.7-1.81.61.7-1.60.8
Conditioned reinforcement - inactives1.51.72.3-1.4-1.41.4-1.4-1.41.4-1.41.41.3-1.3-1.2-1.41.4-1.41.11.4-1.5-1.40.6-1.2
Conditioned locomotion7.28.710.43.13.0-3.13.13.0-3.13.1-3.0-3.03.03.13.0-3.03.0-3.2-2.92.53.0-3.20.4
Patch foraging indifference point 0 sec0.10.20.3-0.3-0.30.4-0.4-0.40.4-0.40.40.5-0.5-0.3-0.50.5-0.50.40.4-0.3-0.40.50.1
Patch foraging indifference point AUC0.91.01.31.11.1-1.11.11.1-1.11.0-1.1-1.01.01.01.1-1.11.1-1.2-1.00.91.0-1.10.1
Delay disc. indifference point, 0s delay3.63.99.7-1.9-1.91.9-1.9-1.91.9-2.01.92.0-2.0-2.0-1.91.9-1.92.41.4-1.0-1.93.11.9
Delay disc. indifference point, 16s delay0.10.10.2-0.3-0.30.3-0.3-0.30.3-0.30.20.3-0.3-0.3-0.30.3-0.30.30.3-0.1-0.20.4-0.1
Delay disc. indifference point, 2s delay3.64.07.3-2.0-2.02.0-2.0-2.02.0-2.02.12.1-2.1-2.0-2.02.0-2.02.41.9-1.4-2.02.70.2
Delay disc. indifference point, 24s delay0.40.40.7-0.6-0.60.6-0.6-0.60.6-0.60.50.7-0.7-0.7-0.80.8-0.80.60.6-0.4-0.60.70.0
Delay disc. indifference point, 4s delay0.40.41.5-0.5-0.50.5-0.5-0.50.5-0.50.50.6-0.6-0.5-0.60.6-0.60.80.3-0.0-0.51.21.1
Delay disc. indifference point, 8s delay1.31.31.5-1.2-1.21.2-1.2-1.21.2-1.21.21.2-1.2-1.2-1.11.1-1.11.11.1-1.2-1.20.9-0.4
Indifference point function ln k0.30.40.5-0.7-0.70.7-0.7-0.70.7-0.70.70.7-0.7-0.6-0.70.7-0.70.70.6-0.6-0.60.6-0.1
Indifference point function log k0.30.40.5-0.7-0.70.7-0.7-0.70.7-0.70.70.7-0.7-0.6-0.70.7-0.70.70.6-0.6-0.60.6-0.1
Patch foraging total patch changes 0 sec0.10.20.3-0.4-0.40.5-0.5-0.50.5-0.40.40.5-0.5-0.4-0.50.5-0.50.40.4-0.4-0.40.4-0.0
Patch foraging total patch changes 12 sec0.60.81.0-0.8-0.80.8-0.8-0.80.8-0.80.81.0-1.0-1.0-1.01.0-1.00.71.0-1.0-0.80.3-0.9
Patch foraging total patch changes 18 sec0.81.01.21.01.0-1.01.01.0-1.01.0-1.0-1.11.11.01.1-1.11.1-1.1-0.90.91.1-1.0-0.1
Patch foraging total patch changes 24 sec0.10.10.20.40.4-0.40.40.4-0.40.4-0.4-0.40.40.30.4-0.40.4-0.4-0.20.50.4-0.2-0.3
Patch foraging total patch changes 6 sec0.10.20.40.60.6-0.50.50.5-0.50.6-0.5-0.30.30.50.3-0.30.3-0.6-0.40.30.3-0.60.2
Patch foraging time to switch 0 sec0.71.02.9-0.9-0.90.9-0.9-0.90.9-0.91.01.1-1.1-1.0-1.11.1-1.11.30.8-0.5-0.91.70.9
Patch foraging water rate 0 sec0.20.31.3-0.5-0.50.4-0.4-0.40.4-0.40.40.4-0.4-0.3-0.50.5-0.50.10.5-0.8-0.6-0.6-1.1
Patch foraging water rate 12 sec2.13.23.8-2.0-2.02.0-2.0-2.01.9-2.01.91.7-1.7-1.7-1.71.7-1.71.61.8-1.9-1.81.0-1.3
Patch foraging water rate 18 sec0.81.07.0-0.9-0.90.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.80.8-0.80.21.1-1.4-0.9-0.9-2.6
Patch foraging water rate 24 sec2.53.58.2-1.8-1.81.8-1.8-1.81.8-1.81.81.8-1.8-1.7-1.91.9-1.91.12.0-2.5-1.9-0.1-2.9
Patch foraging water rate 6 sec0.20.33.5-0.2-0.20.2-0.2-0.20.2-0.20.20.1-0.1-0.1-0.10.1-0.1-0.20.4-0.6-0.1-1.0-1.9
Seeking ratio, delayed vs. immediate footshock5.76.57.62.72.7-2.72.72.7-2.72.7-2.7-2.62.62.72.6-2.62.6-2.6-2.22.52.7-2.3-0.1
Distance traveled before self-admin0.10.10.4-0.3-0.30.3-0.3-0.30.3-0.30.20.3-0.3-0.4-0.20.2-0.20.40.3-0.1-0.20.60.1
Distance traveled after self-admin1.11.21.51.11.1-1.11.11.1-1.11.1-1.2-1.11.11.11.1-1.11.1-1.2-1.01.11.2-1.00.2
Extensor digitorum longus weight5.220.422.4-4.7-4.74.7-4.7-4.74.7-4.74.74.7-4.7-4.7-4.64.6-4.64.64.6-4.5-4.13.9-2.0
Bone: elastic displacement0.30.30.40.60.6-0.60.60.6-0.60.6-0.6-0.60.60.60.7-0.70.7-0.6-0.60.60.4-0.50.3
Bone: elastic work0.00.10.4-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.1-0.10.1-0.10.30.00.0-0.30.50.6
Bone: endosteal estimation0.10.10.8-0.2-0.20.2-0.2-0.20.2-0.20.30.2-0.2-0.2-0.20.2-0.20.50.10.0-0.20.90.9
Bone: endosteal perimeter0.71.42.51.21.2-1.21.21.2-1.21.2-1.1-1.21.21.21.3-1.31.3-0.9-1.31.41.4-0.31.6
Epididymis fat weight0.10.10.70.30.3-0.30.30.3-0.30.3-0.3-0.30.30.20.3-0.30.3-0.5-0.2-0.00.3-0.8-0.7
Delta time in closed arm before/after self-admin2.52.47.4-1.4-1.41.5-1.5-1.51.4-1.41.41.5-1.5-1.6-1.41.4-1.41.01.8-1.8-1.40.2-2.7
Delta time in open arm before/after self-admin1.01.01.7-1.1-1.11.0-1.0-1.01.1-1.11.01.0-1.0-0.9-1.01.0-1.01.20.8-0.8-1.01.30.5
Diff in mean of infusions in LGA sessions1.31.41.81.21.2-1.21.21.2-1.21.2-1.2-1.21.21.31.2-1.21.2-1.3-1.21.01.2-1.40.1
Delay discount exponential model param1.21.32.21.21.2-1.21.21.2-1.21.2-1.1-1.21.21.21.2-1.21.2-1.3-1.10.81.1-1.5-0.2
Extinction: sum of active levers before priming0.40.41.70.50.5-0.50.50.5-0.60.5-0.6-0.60.60.60.5-0.50.5-0.9-0.40.10.5-1.3-1.0
Active lever presses in extinction session 63.23.13.51.81.8-1.81.81.8-1.81.8-1.8-1.91.91.71.8-1.81.8-1.9-1.91.61.8-1.70.8
Bone: final force0.30.62.5-0.6-0.60.6-0.6-0.60.6-0.60.70.7-0.7-0.7-0.70.7-0.71.00.5-0.2-0.41.61.2
Bone: final moment0.30.42.1-0.5-0.50.5-0.5-0.50.5-0.50.60.6-0.6-0.6-0.60.6-0.60.90.4-0.1-0.31.41.2
Food consumed during 24 hour testing period0.50.60.7-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.80.8-0.80.80.7-0.7-0.80.8-0.1
Glucose1.11.72.0-1.3-1.31.3-1.3-1.31.3-1.31.31.4-1.4-1.4-1.41.4-1.41.41.3-1.2-1.41.2-0.4
Heart weight0.10.20.70.40.4-0.30.30.3-0.30.4-0.4-0.50.50.20.4-0.40.4-0.6-0.30.10.3-0.8-0.7
Delay discount hyperbolic model param1.81.93.21.41.4-1.41.41.4-1.41.4-1.4-1.51.51.41.4-1.41.4-1.6-1.31.01.4-1.8-0.2
Intermittent access intake day 1-15 change4.64.67.52.12.1-2.12.12.1-2.12.1-2.1-2.32.32.22.2-2.22.2-2.4-2.01.72.2-2.7-0.4
Intermittent access intake escalation3.02.98.11.61.6-1.61.61.6-1.61.6-1.6-1.71.71.71.7-1.71.7-2.1-1.31.01.6-2.8-1.6
Intermittent access intake escalation 24.34.29.92.02.0-2.02.02.0-2.02.0-2.0-2.12.12.12.1-2.12.1-2.5-1.61.32.0-3.2-1.5
Intermitt. access day 1 inactive lever presses0.10.10.90.30.3-0.30.30.3-0.30.3-0.3-0.20.20.40.3-0.30.3-0.6-0.3-0.10.2-0.9-0.5
Intermitt. access day 15 inactive lever presses0.10.10.60.30.3-0.30.30.3-0.30.3-0.3-0.40.40.40.2-0.20.2-0.5-0.50.00.2-0.70.2
Intermitt. access escalation Index0.20.21.80.20.2-0.20.20.2-0.20.2-0.3-0.30.30.20.2-0.20.20.1-0.30.60.30.81.4
Intermittent access day 1 total infusions0.10.10.2-0.3-0.30.3-0.3-0.30.3-0.30.20.1-0.1-0.2-0.30.3-0.30.30.3-0.2-0.30.4-0.1
Intermittent access day 15 total infusions0.80.92.20.90.9-0.90.90.9-0.90.9-0.9-1.11.10.90.9-0.90.9-1.1-0.60.50.8-1.5-0.9
Intermittent access terminal intake (last 3 days)0.80.91.41.01.0-1.01.01.0-1.01.0-1.0-1.21.21.01.0-1.01.0-1.0-0.80.81.0-1.1-0.1
Intermittent access total infusions0.00.00.20.10.1-0.10.10.1-0.10.1-0.1-0.30.30.20.1-0.10.1-0.20.0-0.00.1-0.4-0.5
Intermittent access day 1 locomotion0.10.10.30.20.2-0.20.20.2-0.20.2-0.2-0.40.40.30.2-0.20.2-0.4-0.10.00.2-0.5-0.4
Intermittent access day 15 total locomotion2.12.24.01.51.5-1.51.51.5-1.51.5-1.4-1.71.71.71.5-1.51.5-1.7-1.31.11.4-2.0-0.5
Intermittent access total locomotion0.70.81.20.90.9-0.90.90.9-0.90.9-0.9-1.11.11.00.9-0.90.9-0.9-0.70.70.9-1.0-0.3
Intermittent access standard deviation2.12.24.01.51.5-1.51.51.5-1.51.5-1.5-1.61.61.51.5-1.51.5-1.7-1.41.11.5-2.0-0.1
Left kidney weight0.20.71.80.80.8-0.80.80.8-0.80.8-0.8-0.80.80.60.8-0.80.8-0.5-0.91.10.90.01.3
Right kidney weight1.64.55.32.22.2-2.22.22.2-2.22.2-2.2-2.32.32.12.2-2.22.2-2.2-2.12.02.3-1.90.8
Cocaine induced anxiety1.82.02.71.51.5-1.51.51.5-1.51.5-1.5-1.41.41.31.5-1.51.5-1.3-1.51.61.5-0.71.2
Post-drug Anxiety1.82.03.31.51.5-1.51.51.5-1.51.5-1.5-1.31.31.21.5-1.51.5-1.2-1.51.81.5-0.41.6
Baseline Anxiety0.00.00.2-0.2-0.20.2-0.2-0.20.2-0.20.20.2-0.2-0.1-0.20.2-0.20.00.2-0.3-0.2-0.2-0.4
Tail length2.26.710.72.62.6-2.62.62.6-2.62.6-2.6-2.72.72.62.7-2.72.7-3.0-2.42.02.5-3.3-0.5
Length with tail1.76.37.52.52.5-2.52.52.6-2.52.6-2.6-2.72.72.72.7-2.72.7-2.7-2.52.22.3-2.60.4
Length without tail0.20.51.20.70.7-0.70.70.7-0.70.7-0.7-0.70.70.90.7-0.70.7-0.5-0.80.90.6-0.01.1
Times rat made contact with spout0.40.50.7-0.6-0.60.7-0.7-0.70.7-0.70.70.8-0.8-0.7-0.80.8-0.80.50.6-0.9-0.40.2-0.4
Lifetime Intake0.00.00.10.10.1-0.10.10.1-0.10.1-0.1-0.30.30.10.1-0.10.1-0.1-0.00.10.1-0.1-0.2
Liver weight, left2.64.24.9-2.1-2.12.1-2.1-2.12.1-2.12.22.1-2.1-2.2-2.12.1-2.12.12.1-2.0-1.91.8-0.9
Liver weight, right1.42.43.1-1.6-1.61.6-1.6-1.61.6-1.61.61.6-1.6-1.6-1.51.5-1.51.71.5-1.3-1.51.8-0.1
Locomotor activity4.26.78.12.62.6-2.72.72.7-2.72.6-2.7-2.72.72.82.7-2.72.7-2.5-2.62.62.8-2.01.2
Locomotor testing distance2.33.84.52.02.0-2.02.02.0-2.02.0-2.0-2.12.12.12.0-2.02.0-1.9-1.91.91.9-1.60.6
Locomotor testing rearing0.00.00.3-0.0-0.00.1-0.1-0.10.1-0.10.0-0.10.1-0.00.0-0.00.0-0.00.1-0.1-0.1-0.1-0.5
Locomotion in novel chamber0.30.40.70.70.7-0.70.70.7-0.70.7-0.7-0.50.50.50.5-0.50.5-0.8-0.50.50.7-0.8-0.3
Locomotion in novel chamber post-restriction0.60.81.00.90.9-0.90.90.9-0.90.9-0.9-0.90.90.81.0-1.01.0-0.9-0.70.81.0-0.8-0.5
Fecal boli incidents, locomotor time 12.52.83.6-1.7-1.71.7-1.7-1.71.7-1.61.61.7-1.7-1.7-1.71.7-1.71.51.8-1.8-1.91.0-1.3
Change in fecal boli incidents, locomotor task1.21.22.31.01.0-1.01.01.0-1.01.0-1.0-1.11.11.01.2-1.21.2-0.7-1.31.31.1-0.11.5
Time >=10cm from walls, locomotor time 10.10.11.7-0.2-0.20.2-0.2-0.20.2-0.10.10.2-0.2-0.2-0.20.2-0.20.4-0.10.2-0.20.71.3
Bouts of movement, locomotor time 10.10.10.30.30.3-0.30.30.3-0.30.4-0.4-0.40.40.40.3-0.30.3-0.5-0.40.20.2-0.50.4
Total resting periods, locomotor time 10.20.30.30.50.5-0.50.50.5-0.50.6-0.6-0.60.60.60.4-0.40.4-0.6-0.50.40.4-0.60.4
Rest time, locomotor task time 10.30.30.40.60.6-0.60.60.6-0.60.6-0.6-0.60.60.60.5-0.50.5-0.5-0.70.60.4-0.30.6
Distance moved, locomotor task time 10.10.21.4-0.2-0.20.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.20.2-0.20.5-0.00.2-0.00.91.2
Vertical activity count, locomotor time 10.10.10.2-0.3-0.30.3-0.3-0.30.3-0.30.30.4-0.4-0.3-0.30.3-0.30.20.3-0.4-0.30.0-0.3
Time >=10cm from walls, locomotor time 21.71.82.0-1.4-1.41.4-1.4-1.41.4-1.41.41.3-1.3-1.3-1.41.4-1.41.31.4-1.3-1.21.1-0.9
Bouts of movement, locomotor time 21.11.23.61.11.1-1.11.11.1-1.11.1-1.1-1.01.01.01.0-1.01.0-0.9-1.41.20.9-0.41.9
Total resting periods, locomotor time 21.21.34.41.11.1-1.11.11.1-1.11.1-1.1-1.01.01.11.0-1.01.0-0.9-1.41.31.0-0.42.1
Rest time, locomotor task time 21.01.21.51.21.2-1.21.21.2-1.21.2-1.2-1.11.11.10.9-0.90.9-1.0-1.11.21.0-0.61.0
Distance moved, locomotor task time 21.41.62.0-1.4-1.41.4-1.4-1.41.4-1.41.41.3-1.3-1.3-1.31.3-1.31.31.2-1.3-1.20.9-0.6
Vertical activity count, locomotor time 21.92.02.6-1.6-1.61.6-1.6-1.51.6-1.51.51.4-1.4-1.4-1.31.3-1.31.31.4-1.6-1.40.7-1.2
Light reinforcement 15.29.411.13.23.2-3.23.23.2-3.23.2-3.2-3.13.13.33.1-3.13.1-3.3-3.02.83.0-3.10.6
Light reinforcement 21.52.02.51.41.4-1.51.51.5-1.51.5-1.4-1.51.51.61.5-1.51.5-1.5-1.41.21.5-1.50.1
Bone: marrow area0.10.20.9-0.3-0.30.3-0.3-0.30.3-0.30.30.2-0.2-0.3-0.20.2-0.20.60.1-0.0-0.20.90.8
Bone: maximum diameter1.52.73.71.71.7-1.71.71.7-1.71.7-1.6-1.71.71.71.7-1.71.7-1.4-1.71.81.9-0.61.7
Bone: maximum force0.50.82.8-0.8-0.80.8-0.8-0.80.8-0.80.90.9-0.9-0.9-0.90.9-0.91.20.7-0.5-0.61.71.0
Bone: maximum moment0.40.72.4-0.7-0.70.7-0.7-0.70.7-0.70.80.8-0.8-0.8-0.80.8-0.81.10.6-0.4-0.51.61.1
Mean time between licks in bursts2.83.96.02.12.1-2.02.02.0-2.02.0-2.0-2.12.12.02.1-2.12.1-2.3-1.81.51.8-2.5-0.5
Mean num. licks in bursts0.10.10.40.30.3-0.20.20.2-0.20.2-0.2-0.10.10.10.1-0.10.1-0.1-0.30.4-0.20.10.6
Cd content in liver0.10.10.2-0.4-0.40.3-0.3-0.30.3-0.30.40.3-0.3-0.3-0.30.3-0.30.40.5-0.2-0.10.5-0.3
Co content in liver0.30.40.90.60.6-0.50.50.5-0.50.5-0.6-0.50.50.60.5-0.50.5-0.8-0.30.30.9-0.9-0.8
Cu content in liver0.20.21.90.20.2-0.20.20.2-0.20.2-0.2-0.20.20.30.2-0.20.20.0-0.50.60.40.51.4
Fe content in liver0.00.00.1-0.2-0.20.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.20.2-0.20.00.2-0.4-0.1-0.2-0.4
K content in liver0.30.31.40.50.5-0.50.50.5-0.50.5-0.5-0.50.50.50.5-0.50.5-0.3-0.60.80.30.21.2
Mg content in liver0.50.52.40.70.7-0.60.60.6-0.60.6-0.7-0.70.70.60.6-0.60.6-0.3-0.81.00.60.21.5
Mn content in liver3.64.18.82.02.0-2.02.02.0-2.02.0-2.0-2.02.01.92.0-2.02.0-1.5-2.32.41.6-0.53.0
Na content in liver0.50.51.4-0.6-0.60.7-0.7-0.70.7-0.70.70.7-0.7-0.7-0.70.7-0.70.90.5-0.3-0.71.20.8
Rb content in liver0.10.10.90.10.1-0.00.00.0-0.00.0-0.1-0.10.10.00.0-0.00.00.3-0.10.5-0.00.91.0
Se content in liver0.20.30.40.60.6-0.50.50.5-0.50.5-0.6-0.50.50.50.5-0.50.5-0.5-0.60.60.4-0.40.6
Sr content in liver0.30.31.8-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.50.5-0.50.20.6-0.8-0.5-0.3-1.3
Zn content in liver0.60.73.50.70.7-0.60.60.6-0.60.6-0.7-0.70.70.60.6-0.60.6-1.2-0.40.00.7-1.9-1.6
Bone: minimum diameter0.10.31.50.40.4-0.40.40.4-0.40.4-0.4-0.40.40.40.4-0.40.4-0.1-0.60.60.50.31.2
Time in familiar zone, hab. session 11.51.42.51.21.2-1.21.21.2-1.21.2-1.2-1.21.21.21.2-1.21.2-1.4-1.10.91.1-1.6-0.3
Time in novel zone, hab. session 10.30.31.5-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.50.5-0.50.80.2-0.0-0.11.21.2
Total zone transitions, hab. session 11.82.53.31.61.6-1.61.61.6-1.61.6-1.6-1.61.61.61.6-1.61.6-1.4-1.71.81.2-0.81.7
Total locomotion distance, hab. session 13.04.27.12.12.1-2.12.12.1-2.12.1-2.1-2.02.02.02.0-2.02.0-1.7-2.32.51.8-0.82.7
Locomotion velocity, hab. session 13.04.35.72.12.1-2.12.12.1-2.12.1-2.1-2.12.12.12.1-2.12.1-1.8-2.32.41.8-1.12.2
Time in familiar zone, hab. session 24.14.28.02.12.1-2.12.12.1-2.12.1-2.1-2.12.12.12.1-2.12.1-2.5-1.81.42.1-2.8-0.8
Time in novel zone, hab. session 22.62.65.9-1.6-1.61.6-1.6-1.61.6-1.61.61.6-1.6-1.6-1.61.6-1.62.01.3-1.0-1.62.41.1
Total zone transitions, hab. session 20.30.43.90.40.4-0.40.40.4-0.40.4-0.4-0.20.20.30.2-0.20.20.1-0.60.9-0.50.72.0
Total locomotion distance, hab. session 21.62.12.91.61.6-1.61.61.6-1.61.6-1.6-1.41.41.51.4-1.41.4-1.3-1.61.70.7-0.91.6
Locomotion velocity, hab. session 21.82.53.91.71.7-1.71.71.7-1.71.7-1.7-1.51.51.61.5-1.51.5-1.3-1.81.90.9-0.72.0
Novel to familiar place preference ratio1.81.95.2-1.3-1.31.3-1.3-1.31.3-1.31.31.3-1.3-1.3-1.31.3-1.31.71.0-0.6-1.52.31.2
Novelty place preference0.90.93.1-0.9-0.90.9-0.9-0.90.9-0.90.90.9-0.9-0.9-0.90.9-0.91.30.6-0.3-1.11.81.2
Time in novel zone, NPP test1.21.23.5-1.0-1.01.0-1.0-1.01.0-1.01.01.0-1.0-1.0-1.01.0-1.01.40.8-0.5-1.21.91.1
Total zone transitions, NPP test0.10.21.20.30.3-0.30.30.3-0.30.3-0.3-0.20.20.30.2-0.20.2-0.1-0.40.5-0.40.21.1
Total locomotion distance, NPP test0.20.32.50.50.5-0.50.50.5-0.50.5-0.5-0.30.30.40.3-0.30.3-0.2-0.60.8-0.10.31.6
Locomotion velocity, NPP test0.40.52.40.70.7-0.70.70.7-0.70.7-0.7-0.60.60.70.6-0.60.6-0.4-0.91.00.10.01.5
Intraocular pressure0.20.32.7-0.3-0.30.3-0.3-0.30.3-0.30.30.5-0.5-0.4-0.40.4-0.4-0.00.6-0.7-0.4-0.6-1.6
Delta distance traveled before/after self-admin1.51.61.91.31.3-1.31.31.3-1.31.3-1.3-1.31.31.41.3-1.31.3-1.4-1.21.11.3-1.30.1
Delta ambulatory time before/after self-admin2.12.32.51.61.6-1.61.61.6-1.61.6-1.6-1.51.51.61.5-1.51.5-1.5-1.51.51.6-1.30.6
Parametrial fat weight0.30.51.00.70.7-0.70.70.7-0.70.7-0.7-0.80.80.80.7-0.70.7-0.9-0.60.40.8-1.0-0.4
Pavlov. Cond. lever latency0.30.32.0-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.50.5-0.50.20.6-0.8-0.4-0.3-1.4
Pavlov. Cond. magazine entry latency2.02.63.71.71.7-1.71.71.7-1.71.7-1.7-1.71.71.71.7-1.71.7-1.8-1.61.31.4-1.90.0
Pavlov. Cond. change in total contacts0.10.10.10.30.3-0.30.30.3-0.30.3-0.3-0.30.30.30.3-0.30.3-0.3-0.40.30.0-0.30.3
Pavlov. Cond. index score0.70.91.11.01.0-1.01.01.0-1.01.0-1.0-0.90.91.00.9-0.90.9-0.8-1.11.10.7-0.51.1
Pavlov. Cond. latency score0.91.22.01.11.1-1.11.11.1-1.11.1-1.1-1.11.11.11.1-1.11.1-0.9-1.21.30.9-0.41.4
Pavlov. Cond. lever contacts0.70.83.20.80.8-0.80.80.8-0.80.8-0.8-0.80.80.80.8-0.80.8-0.5-1.01.20.80.11.8
Pavlov. Cond. magazine entry number0.50.60.7-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.80.8-0.80.90.8-0.7-0.60.8-0.3
Pavlov. Cond. intertrial magazine entries0.10.11.1-0.0-0.00.0-0.0-0.00.0-0.00.10.2-0.2-0.1-0.10.1-0.1-0.20.2-0.40.0-0.6-1.0
Pavlov. Cond. lever-magazine prob. diff.1.11.31.71.21.2-1.21.21.2-1.21.2-1.2-1.21.21.21.2-1.21.2-1.1-1.31.21.0-0.81.1
Pavlov. Cond. response bias1.01.21.41.11.1-1.11.11.1-1.11.1-1.1-1.11.11.11.1-1.11.1-1.2-1.11.01.0-1.10.4
Pavlov. Cond. lever latency1.01.31.7-1.2-1.21.2-1.2-1.21.2-1.21.21.2-1.2-1.2-1.21.2-1.21.20.9-1.1-1.31.10.4
Pavlov. Cond. magazine entry latency0.70.81.30.90.9-0.90.90.9-0.90.9-0.9-1.01.01.01.0-1.01.0-0.8-0.80.91.2-0.60.2
Pavlov. Cond. change in total contacts0.81.21.51.11.1-1.11.11.1-1.11.1-1.1-1.11.11.11.1-1.11.1-1.2-0.90.91.2-1.2-0.3
Pavlov. Cond. index score1.01.31.91.21.2-1.11.11.1-1.11.1-1.1-1.21.21.21.2-1.21.2-1.2-0.91.01.4-1.1-0.4
Pavlov. Cond. latency score1.11.32.11.21.2-1.11.11.1-1.11.1-1.2-1.21.21.21.2-1.21.2-1.2-1.01.11.4-1.0-0.0
Pavlov. Cond. lever contacts0.70.91.31.01.0-1.01.01.0-1.01.0-1.0-1.01.00.91.0-1.01.0-1.1-0.70.71.0-1.2-0.8
Pavlov. Cond. magazine entry number1.21.41.9-1.3-1.31.2-1.2-1.21.2-1.21.21.3-1.3-1.3-1.31.3-1.31.21.0-1.2-1.40.90.0
Pavlov. Cond. intertrial magazine entries0.91.22.0-1.1-1.11.1-1.1-1.11.1-1.11.11.2-1.2-1.1-1.21.2-1.21.01.2-1.2-1.40.6-1.0
Pavlov. Cond. lever-magazine prob. diff.1.11.42.01.31.3-1.21.21.2-1.21.2-1.2-1.31.31.21.3-1.31.3-1.2-1.01.11.4-1.1-0.2
Pavlov. Cond. response bias1.62.23.01.51.5-1.51.51.5-1.51.5-1.5-1.51.51.51.5-1.51.5-1.7-1.11.21.6-1.7-0.8
Time in closed arm before self-admin0.30.31.4-0.5-0.50.4-0.4-0.40.5-0.50.50.5-0.5-0.3-0.50.5-0.50.80.4-0.1-0.51.20.8
Time in closed arm after self-admin0.10.11.20.20.2-0.10.10.1-0.20.2-0.20.0-0.00.00.1-0.10.1-0.20.20.10.2-0.3-1.1
Time in open arm before self-admin0.80.91.61.01.0-0.90.90.9-1.01.0-0.9-0.90.90.80.9-0.90.9-1.1-1.00.71.0-1.30.2
Time in open arm after self-admin0.91.01.3-1.1-1.11.1-1.1-1.11.1-1.11.11.0-1.0-1.0-1.11.1-1.11.10.7-1.1-1.10.90.5
Bone: periosteal estimation0.10.22.6-0.0-0.00.0-0.0-0.00.0-0.00.10.0-0.0-0.0-0.00.0-0.00.5-0.20.40.21.21.6
Bone: periosteal perimeter0.61.03.10.90.9-0.90.90.9-0.90.9-0.9-1.01.01.01.0-1.01.0-0.5-1.11.21.20.21.8
Bone: post-yield work0.60.80.9-0.9-0.90.9-0.9-0.90.9-0.90.90.9-0.9-0.9-0.90.9-0.90.90.8-0.8-0.70.9-0.1
Progressive ratio test 1 active lever presses0.40.40.6-0.7-0.70.7-0.7-0.70.7-0.70.60.4-0.4-0.6-0.70.7-0.70.50.8-0.7-0.70.3-0.8
Progressive ratio test 1 breakpoint0.40.40.6-0.7-0.70.7-0.7-0.70.7-0.70.60.4-0.4-0.7-0.70.7-0.70.50.8-0.6-0.70.5-0.7
Progressive ratio test 1 inactive lever presses0.00.00.00.10.1-0.10.10.1-0.10.1-0.0-0.10.10.10.0-0.00.0-0.1-0.00.00.0-0.0-0.0
Progressive ratio test 2 active lever presses0.10.10.30.20.2-0.20.20.2-0.20.2-0.2-0.30.30.20.2-0.20.2-0.3-0.20.00.2-0.6-0.2
Progressive ratio test 2 breakpoint0.30.30.40.60.6-0.60.60.6-0.60.6-0.6-0.60.60.50.6-0.60.6-0.6-0.60.50.6-0.60.4
Progressive ratio test 2 inactive lever presses0.10.10.20.30.3-0.30.30.3-0.30.3-0.3-0.30.30.30.2-0.20.2-0.2-0.40.30.2-0.20.4
Incentive Sensitization - Responses0.20.20.50.40.4-0.40.40.4-0.40.4-0.4-0.30.30.30.4-0.40.4-0.5-0.50.20.4-0.7-0.0
Incentive Sensitization - Breakpoint0.30.30.60.60.6-0.60.60.6-0.60.6-0.6-0.50.50.40.6-0.60.6-0.6-0.60.40.6-0.80.2
Sum of active levers in priming session hrs 5-60.00.00.4-0.2-0.20.2-0.2-0.20.2-0.20.10.1-0.1-0.1-0.20.2-0.20.10.3-0.2-0.20.0-0.6
Progressive ratio0.30.30.5-0.5-0.50.5-0.5-0.50.5-0.50.50.7-0.7-0.7-0.50.5-0.50.40.2-0.6-0.60.20.5
Food seeking constrained by brief footshock0.10.10.20.30.3-0.30.30.3-0.30.3-0.3-0.30.30.30.3-0.30.3-0.4-0.30.30.5-0.30.0
Seeking ratio, punishment vs. effort0.10.10.60.30.3-0.30.30.3-0.30.3-0.3-0.40.40.50.3-0.30.3-0.30.10.40.4-0.2-0.8
Retroperitoneal fat weight0.82.53.3-1.7-1.71.6-1.6-1.61.6-1.61.61.5-1.5-1.4-1.61.6-1.61.51.6-1.7-1.81.1-1.1
Reaction time number correct1.31.92.3-1.4-1.41.4-1.4-1.41.4-1.41.41.4-1.4-1.4-1.41.4-1.41.21.4-1.5-1.40.6-1.2
Reaction time mean minus median1.01.31.81.31.3-1.21.21.2-1.21.3-1.2-1.21.21.01.2-1.21.2-1.2-1.01.11.0-1.0-0.1
Reaction time mean minus median AUC0.60.81.91.01.0-0.90.90.9-0.90.9-0.9-0.90.90.70.9-0.90.9-0.5-0.91.20.50.21.4
Reaction time num false alarms0.10.10.2-0.3-0.30.3-0.3-0.30.3-0.30.30.3-0.3-0.4-0.30.3-0.30.20.2-0.4-0.40.1-0.1
Reaction time num false alarms AUC0.20.30.6-0.5-0.50.6-0.6-0.60.6-0.60.60.6-0.6-0.7-0.60.6-0.60.40.6-0.7-0.70.1-0.6
Reaction time trials correct on left1.31.92.3-1.4-1.41.4-1.4-1.41.4-1.41.41.4-1.4-1.4-1.41.4-1.41.21.4-1.5-1.40.6-1.2
Reaction time trials on left1.21.82.1-1.4-1.41.4-1.4-1.41.4-1.41.41.3-1.3-1.3-1.31.3-1.31.21.4-1.5-1.40.6-1.1
Reaction time mean0.20.30.70.70.7-0.60.60.6-0.60.6-0.6-0.60.60.40.6-0.60.6-0.2-0.50.80.40.30.7
Reaction time mean AUC0.20.20.50.50.5-0.40.40.4-0.40.5-0.4-0.40.40.30.4-0.40.4-0.1-0.30.70.30.40.7
Median of all reaction times0.10.10.80.00.00.0-0.0-0.00.0-0.00.00.0-0.0-0.1-0.00.0-0.00.40.00.3-0.10.90.8
Reaction time omissions0.30.40.60.70.7-0.70.70.7-0.70.7-0.7-0.80.80.70.7-0.70.7-0.6-0.60.70.5-0.40.1
Reaction time false alarm rate0.00.00.10.20.2-0.10.10.1-0.10.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.10.1-0.00.10.2
Reaction time premature initiation rate0.30.41.70.70.7-0.60.60.6-0.60.6-0.6-0.50.50.70.6-0.60.6-0.9-0.50.20.3-1.3-0.7
Reaction time premature initiations0.20.22.2-0.0-0.00.1-0.1-0.10.1-0.10.10.2-0.20.0-0.10.1-0.1-0.40.2-0.6-0.4-1.1-1.5
Std. dev. reaction times0.60.91.21.11.1-1.01.01.0-1.01.0-1.0-1.01.00.81.0-1.01.0-0.8-0.91.00.6-0.40.6
Reaction time trials completed1.21.82.1-1.4-1.41.4-1.4-1.41.4-1.41.41.3-1.3-1.3-1.31.3-1.31.21.4-1.5-1.40.6-1.1
Reaction time trials AUC1.31.92.5-1.5-1.51.5-1.5-1.51.4-1.51.41.4-1.4-1.4-1.41.4-1.41.21.4-1.6-1.40.6-1.3
Run reversals in cocaine runway, females1.51.41.91.21.2-1.21.21.2-1.21.2-1.2-1.11.11.11.1-1.11.1-1.1-1.31.31.3-0.81.4
Run reversals in cocaine runway, males2.12.12.91.71.7-1.61.61.6-1.61.7-1.5-1.51.51.31.4-1.41.4-1.4-1.11.51.5-1.1-0.0
Latency to leave start box in cocaine runway2.02.23.01.51.5-1.51.51.5-1.51.5-1.6-1.61.61.61.5-1.51.5-1.2-1.51.71.5-0.61.4
Latency to leave start box in cocaine runway, F0.80.93.40.90.9-0.90.90.9-0.90.9-0.9-1.01.00.80.8-0.80.8-0.4-0.91.40.90.51.8
Latency to leave start box in cocaine runway, M1.31.23.20.90.9-1.01.01.0-1.00.9-1.1-1.21.21.11.2-1.21.2-1.4-1.10.61.0-1.8-0.6
Std. dev. time between licks in bursts1.51.82.21.31.3-1.31.31.3-1.31.3-1.4-1.31.31.41.3-1.31.3-1.2-1.41.51.4-0.71.3
Total sessions with >9 infusions0.30.30.70.50.5-0.50.50.5-0.50.5-0.5-0.70.70.40.5-0.50.5-0.2-0.50.70.50.20.9
Short access day 1 total inactive lever presses0.00.00.20.10.1-0.10.10.1-0.10.1-0.1-0.20.20.10.1-0.10.1-0.10.00.10.1-0.2-0.4
Short access day 10 total inactive lever presses0.10.10.6-0.2-0.20.2-0.2-0.20.2-0.20.20.1-0.1-0.1-0.20.2-0.2-0.10.2-0.4-0.2-0.4-0.8
Short access day 1 total infusions0.40.50.90.70.7-0.70.70.7-0.70.7-0.7-0.90.90.60.7-0.70.7-0.4-0.40.90.70.00.2
Short access day 10 total infusions0.00.00.10.00.0-0.00.00.0-0.00.00.0-0.10.1-0.1-0.00.0-0.00.00.10.0-0.00.1-0.2
Short access total infusions0.10.10.30.30.3-0.30.30.3-0.30.3-0.3-0.50.50.20.3-0.30.3-0.1-0.20.50.30.20.3
Short access day 1 locomotion0.80.81.40.90.9-0.90.90.9-0.90.9-0.9-1.21.21.10.9-0.90.9-0.8-0.80.90.9-0.70.4
Short access day 10 total locomotion2.52.85.21.71.7-1.71.71.7-1.71.7-1.6-1.81.81.81.7-1.71.7-1.9-1.61.21.7-2.3-0.3
Short access total locomotion0.80.91.50.90.9-0.90.90.9-0.90.9-0.9-1.21.21.11.0-1.01.0-0.9-0.80.91.0-0.80.0
One hour access (0.3 mA shock)0.30.40.5-0.7-0.70.7-0.7-0.70.7-0.70.70.5-0.5-0.6-0.70.7-0.70.70.6-0.6-0.70.5-0.1
Compulsive drug intake0.50.50.9-0.7-0.70.7-0.7-0.70.7-0.70.70.9-0.9-0.8-0.70.7-0.70.80.7-0.5-0.71.00.1
One hour access (shock baseline)0.10.10.2-0.3-0.30.3-0.3-0.30.3-0.30.30.1-0.1-0.2-0.30.3-0.30.10.3-0.5-0.3-0.2-0.4
Social response proportion1.01.11.51.11.1-1.11.11.1-1.01.1-1.0-1.01.01.01.1-1.11.1-1.0-1.21.00.9-0.81.2
Social responses9.312.013.43.63.6-3.63.63.6-3.63.6-3.6-3.73.73.53.6-3.63.6-3.5-3.53.43.3-3.01.5
Social time1.01.32.0-1.2-1.21.2-1.2-1.21.2-1.21.21.1-1.1-1.1-1.11.1-1.11.21.1-1.1-1.41.0-0.4
Soleus weight7.822.927.3-4.9-4.95.0-5.0-5.05.0-5.05.04.9-4.9-5.0-4.94.9-4.95.24.8-4.3-4.55.2-0.9
Bone: stiffness1.72.85.5-1.6-1.61.6-1.6-1.61.6-1.61.71.8-1.8-1.7-1.81.8-1.82.01.5-1.3-1.12.30.7
Tibialis anterior weight0.82.63.3-1.7-1.71.7-1.7-1.71.7-1.71.71.7-1.7-1.7-1.61.6-1.61.81.7-1.4-1.01.8-0.6
Time to tail flick, vehicle, before self-admin1.71.72.71.41.4-1.31.31.3-1.41.4-1.4-1.41.41.21.4-1.41.4-1.1-1.11.61.4-0.60.4
Time to tail flick, vehicle, after self-admin0.00.00.3-0.1-0.10.1-0.1-0.10.0-0.10.00.1-0.1-0.2-0.10.1-0.1-0.2-0.0-0.3-0.1-0.6-0.4
Time to tail flick, test, before self-admin1.11.12.91.01.0-1.01.01.0-1.01.0-0.9-1.11.10.91.0-1.01.0-0.7-1.21.31.0-0.11.7
Time to tail flick, test, after self-admin0.60.60.90.80.8-0.80.80.8-0.80.8-0.8-0.90.90.70.8-0.80.8-0.6-0.80.90.8-0.30.8
Delta time to tail flick, vehicle, before/after SA1.61.62.6-1.3-1.31.3-1.3-1.31.3-1.31.31.3-1.3-1.3-1.31.3-1.31.01.1-1.6-1.30.3-0.8
Delta time to tail flick, test, before/after SA0.10.11.5-0.2-0.20.2-0.2-0.20.1-0.20.10.1-0.1-0.1-0.10.1-0.1-0.10.4-0.4-0.1-0.5-1.2
Tibia length0.61.82.91.31.3-1.31.31.3-1.31.3-1.3-1.41.41.41.4-1.41.4-1.5-1.41.01.5-1.70.1
Ambulatory time before self-admin0.10.10.3-0.4-0.40.4-0.4-0.40.4-0.40.30.3-0.3-0.4-0.30.3-0.30.40.4-0.2-0.40.5-0.0
Ambulatory time after self-admin0.60.60.80.80.8-0.80.80.8-0.80.8-0.9-0.80.80.90.8-0.80.8-0.8-0.70.80.8-0.70.0
Bone: tissue strength1.41.42.5-1.2-1.21.2-1.2-1.21.2-1.21.21.1-1.1-1.1-1.11.1-1.11.41.1-0.9-1.41.60.3
Total heroin consumption2.12.52.91.71.7-1.61.61.6-1.61.7-1.6-1.71.71.61.6-1.61.6-1.6-1.61.51.6-1.50.5
Bone: trabecular number2.13.34.51.91.9-1.91.91.9-1.91.9-1.9-1.81.81.81.8-1.81.8-1.6-1.92.12.1-0.81.8
Bone: trabecular spacing2.53.27.0-1.8-1.81.8-1.8-1.81.8-1.81.81.7-1.7-1.8-1.71.7-1.71.21.9-2.2-2.10.2-2.7
Bone: trabecular thickness2.73.213.11.61.6-1.61.61.6-1.61.6-1.6-1.61.61.61.6-1.61.6-0.9-1.92.41.90.63.6
Bone: trabecular tissue density3.65.15.8-2.4-2.42.4-2.4-2.42.4-2.42.42.2-2.2-2.3-2.22.2-2.22.32.3-2.3-2.21.8-1.4
Water consumed over 24 hours0.10.21.2-0.2-0.20.3-0.3-0.30.3-0.30.30.3-0.3-0.3-0.30.3-0.30.50.10.10.11.01.1
Number of responses in last shaping day0.20.20.30.40.4-0.40.40.4-0.40.4-0.4-0.50.50.40.4-0.40.4-0.4-0.30.40.4-0.3-0.0