Hub : Genes

Znf235

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA intron excision ratio chr1_88830013_88833453 0.07 0.05 2.2e-03 0.02 0.02 0.04 0.04 2.0e-02 1.8e-02 4.2e-03 4.1e-03
2 RMTg mRNA stability Znf235 0.24 0.15 5.1e-04 0.04 0.04 0.01 0.03 3.2e-02 3.3e-02 1.5e-01 7.1e-02
3 NAcc gene expression Znf235 0.11 0.06 1.9e-15 0.1 0.09 0.09 0.09 1.2e-14 1.2e-13 1.1e-13 4.8e-14
4 PL gene expression Znf235 0.03 0.02 1.2e-03 0.02 0.03 0.04 0.03 3.6e-03 9.1e-04 1.0e-04 8.6e-04
5 Liver gene expression Znf235 0.05 0.04 1.1e-04 0.03 0.03 0.02 0.03 2.0e-04 5.4e-04 2.0e-03 4.6e-04
6 LHb intron excision ratio chr1_88830013_88830131 0.18 0.12 2.6e-03 0.06 0.11 0.1 0.08 1.7e-02 1.6e-03 2.4e-03 6.6e-03
7 LHb intron excision ratio chr1_88830013_88833453 0.21 0.12 1.5e-03 0.06 0.12 0.1 0.09 1.9e-02 1.2e-03 2.7e-03 4.4e-03
8 Adipose gene expression Znf235 0.45 0.25 2.4e-07 0.04 0.05 0.05 0.05 1.8e-05 4.5e-06 2.2e-06 2.8e-06
9 OFC gene expression Znf235 0.16 0.1 2.7e-03 0.11 0.13 0.12 0.12 1.2e-03 4.8e-04 1.1e-03 8.8e-04
10 Liver mRNA stability Znf235 0.06 0.05 1.4e-04 0.02 0.03 0.03 0.03 3.1e-03 1.9e-04 1.0e-04 1.3e-04
11 Brain gene expression Znf235 0.22 0.1 0.0e+00 0.19 0.19 0.18 0.19 1.7e-17 9.7e-18 1.0e-16 2.7e-17
12 Adipose mRNA stability Znf235 0.08 0.06 3.8e-05 0.03 0.03 0.02 0.03 2.8e-04 2.4e-04 9.7e-04 6.7e-04
13 pVTA gene expression Znf235 0.05 0.04 8.9e-03 0 0.01 0.01 0 3.3e-01 4.8e-02 2.0e-02 2.0e-01
14 pVTA intron excision ratio chr1_88830013_88833453 0.04 0.03 7.1e-03 0.01 0.02 0.02 0.01 6.5e-02 1.5e-02 4.4e-03 4.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.10.20.40.4-0.30.50.60.5-0.10.00.5-0.50.1-0.5-0.20.40.5
Area under the delay curve0.91.43.9-1.21.4-0.2-0.8-0.11.9-1.91.1-0.01.1-0.3-2.01.00.8
BMI with tail0.72.54.31.8-1.92.01.62.1-1.31.22.0-1.8-1.6-1.70.31.00.9
BMI without tail0.21.22.11.5-1.41.01.31.3-1.11.11.3-1.1-1.2-1.00.60.40.4
Body weight1.14.79.02.5-2.43.02.32.9-1.61.52.4-2.7-1.8-2.60.31.71.0
Weight adjusted by age0.00.00.2-0.2-0.0-0.2-0.3-0.1-0.10.1-0.40.2-0.30.20.2-0.3-0.2
Bone surface0.40.71.31.1-0.91.10.91.1-0.60.61.0-1.0-0.5-1.00.11.0-0.2
Bone volume0.30.61.21.1-0.71.10.71.0-0.30.30.8-1.0-0.1-1.0-0.21.1-0.4
Breakpoint value in progressive ratio session0.71.33.1-1.01.6-1.1-1.0-0.91.8-1.80.40.81.50.6-1.50.20.3
Number of licking bursts0.51.55.02.2-1.31.31.41.3-0.80.80.6-1.3-1.3-1.20.21.0-0.7
Context. condit. distance diff. score0.40.42.00.8-0.50.70.30.6-0.20.20.8-0.6-0.1-0.6-0.10.9-1.4
Locomotion velocity, session 10.20.20.6-0.00.30.3-0.60.30.6-0.6-0.2-0.40.4-0.5-0.80.8-0.5
Locomotion distance, session 10.20.21.00.4-0.20.60.60.5-0.0-0.0-0.0-0.6-0.2-0.6-0.20.71.0
Locomotion velocity, session 20.50.61.80.8-0.80.30.60.2-0.90.9-1.3-0.1-0.80.10.9-0.8-0.7
Locomotion distance, session 20.30.41.50.5-0.60.20.70.1-0.80.8-1.2-0.1-0.70.10.8-0.60.4
Locomotion velocity, session 30.30.30.90.3-0.4-0.10.1-0.2-0.70.7-0.80.3-0.40.40.9-0.6-0.9
Locomotion distance, session 31.82.14.5-1.40.9-1.9-1.2-1.90.00.1-2.02.10.72.11.0-1.9-0.4
Stereotopy head waving bouts, day 30.70.92.70.6-0.9-0.00.8-0.1-1.41.5-0.60.4-1.00.51.6-1.10.5
Stereotopy head waving duration, day 30.70.92.01.4-1.31.01.20.9-1.11.10.3-0.7-1.2-0.70.80.2-0.2
Locomotion velocity, session 70.10.10.40.10.1-0.10.5-0.20.1-0.1-0.40.10.10.1-0.1-0.20.7
Locomotion distance, session 70.20.20.50.7-0.50.60.60.7-0.10.10.4-0.6-0.3-0.6-0.20.4-0.2
Stereotopy head waving bouts, day 70.50.61.51.0-1.00.41.00.4-1.21.20.2-0.2-1.0-0.11.2-0.00.1
Stereotopy head waving duration, day 70.40.51.01.0-0.90.70.70.6-0.90.90.3-0.5-1.0-0.40.70.3-0.8
Locomotion velocity, session 80.60.71.9-0.50.3-0.8-0.9-0.9-0.20.2-1.11.00.21.00.7-1.1-1.4
Locomotion distance, session 80.10.10.40.5-0.10.40.40.2-0.10.1-0.6-0.3-0.0-0.30.00.30.0
Degree of sensitization distance2.42.65.81.6-1.12.21.42.20.0-0.12.2-2.3-0.6-2.4-1.22.00.2
Degree of sensitization stereotypy0.50.61.31.0-1.00.50.90.5-1.11.10.2-0.4-1.0-0.21.00.2-0.2
Conditioned locomotion2.32.79.3-0.60.3-1.8-0.3-1.9-0.91.0-3.12.1-0.12.32.0-2.20.8
Cocaine response after cond. corrected0.50.71.51.0-1.00.10.90.3-1.21.2-0.8-0.1-1.10.11.2-0.60.2
Cocaine response after cond. not corrected1.21.74.01.5-1.60.21.30.3-2.02.0-0.8-0.1-1.70.32.0-1.1-0.0
Cocaine response before conditioning1.11.33.71.1-1.3-0.00.70.0-1.81.8-0.20.1-1.40.41.9-1.1-1.0
Saline control response1.11.52.51.5-1.51.31.61.5-1.11.11.5-1.4-1.1-1.20.50.80.3
Bone: connectivity density0.20.31.50.0-0.10.30.60.30.1-0.11.0-0.40.2-0.4-0.20.51.2
Bone: cortical apparent density0.10.10.4-0.10.3-0.10.10.10.5-0.50.4-0.20.4-0.3-0.70.50.4
Bone: cortical area0.71.22.41.6-1.31.31.01.2-1.00.90.6-1.2-1.0-1.10.40.7-1.2
Bone: cortical porosity4.24.612.4-1.61.0-2.4-1.1-2.5-0.60.7-3.52.70.32.92.0-3.31.8
Bone: cortical porosity2.93.28.3-1.00.5-1.9-0.6-1.9-0.91.0-2.92.2-0.12.42.0-2.81.9
Bone: cortical thickness0.20.41.01.0-0.80.70.90.6-0.70.7-0.0-0.6-0.7-0.50.40.20.1
Bone: cortical thickness0.81.01.81.3-1.21.01.20.8-1.31.3-0.8-0.7-1.3-0.51.0-0.40.5
Bone: cortical tissue density0.10.10.4-0.20.4-0.20.0-0.00.6-0.60.3-0.10.5-0.2-0.60.40.5
Condit. Reinf. active minus inactive responses0.50.61.50.9-0.90.50.80.8-0.70.71.0-0.6-0.4-0.50.40.2-1.2
Condit. Reinf. active-inactive response ratio0.70.71.21.0-1.00.90.91.0-0.70.71.0-0.9-0.6-0.80.30.6-1.1
Condit. Reinf. active responses0.30.40.70.9-0.80.30.80.6-0.70.70.7-0.4-0.4-0.30.5-0.0-0.6
Condit. Reinf. inactive responses0.00.10.60.0-0.0-0.10.2-0.0-0.00.00.40.10.00.10.1-0.20.8
Incentive salience index mean0.20.20.60.5-0.5-0.20.80.1-0.70.70.20.1-0.30.20.8-0.6-0.1
Condit. Reinf. lever presses0.40.54.7-0.00.1-0.70.8-0.4-0.20.2-0.60.4-0.10.60.4-0.72.2
Condit. Reinf. active minus inactive responses0.20.31.10.7-0.50.10.20.0-0.70.7-0.20.0-0.60.10.7-0.3-1.1
Condit. Reinf. active-inactive response ratio0.71.02.91.0-1.00.00.5-0.1-1.51.5-1.20.3-1.20.51.7-0.8-0.8
Condit. Reinf. active responses0.20.21.0-0.30.3-0.5-0.5-0.70.00.0-0.20.60.00.60.3-0.7-1.0
Condit. Reinf. inactive responses0.50.71.8-1.31.1-0.8-0.9-0.81.1-1.10.70.61.00.4-0.8-0.5-0.3
Condit. Reinf. lever presses0.71.02.81.1-0.71.30.81.2-0.10.11.7-1.3-0.7-1.3-0.51.0-0.5
Condit. Reinf. lever reinforcers received0.20.30.8-0.40.3-0.7-0.5-0.8-0.00.1-0.30.80.00.80.4-0.9-0.9
Conditioned reinforcement - actives0.41.73.11.0-1.71.11.71.1-1.81.70.8-0.8-1.5-0.71.4-0.31.6
Conditioned reinforcement - inactives0.10.30.80.0-0.90.10.70.4-0.90.9-0.2-0.2-0.2-0.10.7-0.50.7
Conditioned locomotion1.31.93.81.5-1.91.21.61.2-2.01.90.2-0.9-1.9-0.71.6-0.30.1
Patch foraging indifference point 0 sec0.10.31.00.7-0.70.30.70.3-0.70.70.4-0.2-0.3-0.10.6-0.21.0
Patch foraging indifference point AUC0.82.03.21.6-1.71.41.81.3-1.81.81.3-1.1-1.7-0.91.30.2-0.1
Delay disc. indifference point, 0s delay1.11.22.2-1.41.2-1.5-0.9-1.41.0-0.9-1.01.30.41.2-0.4-0.91.3
Delay disc. indifference point, 16s delay0.91.34.3-0.81.10.3-0.30.41.8-1.81.2-0.51.2-0.7-2.11.10.6
Delay disc. indifference point, 2s delay2.62.98.1-1.52.2-0.3-1.4-0.22.7-2.81.1-0.01.7-0.4-2.81.60.8
Delay disc. indifference point, 24s delay0.91.53.21.2-0.61.80.81.80.0-0.11.1-1.6-1.0-1.7-0.91.70.5
Delay disc. indifference point, 4s delay0.10.10.4-0.1-0.1-0.10.1-0.0-0.10.10.60.2-0.30.10.10.20.6
Delay disc. indifference point, 8s delay0.81.33.3-1.41.4-0.3-1.0-0.31.8-1.80.70.21.5-0.1-1.80.80.2
Indifference point function ln k0.20.61.2-0.91.0-0.6-1.0-0.61.1-1.1-0.80.41.00.3-0.90.2-0.1
Indifference point function log k0.20.61.2-0.91.0-0.6-1.0-0.61.1-1.1-0.80.41.00.3-0.90.2-0.1
Patch foraging total patch changes 0 sec0.20.71.31.1-0.90.81.10.8-0.80.80.9-0.8-0.4-0.70.40.31.1
Patch foraging total patch changes 12 sec0.70.92.31.0-1.10.31.10.2-1.51.5-0.0-0.0-1.10.21.5-1.00.3
Patch foraging total patch changes 18 sec1.12.76.22.0-1.82.01.71.9-1.41.32.5-1.9-1.3-1.80.51.2-0.3
Patch foraging total patch changes 24 sec0.20.82.30.9-0.90.91.20.8-0.80.81.5-0.7-0.6-0.70.40.21.2
Patch foraging total patch changes 6 sec1.01.73.61.4-1.70.71.70.8-1.91.90.7-0.5-1.5-0.31.7-0.61.2
Patch foraging time to switch 0 sec0.93.57.2-2.42.4-1.7-2.7-1.72.2-2.2-0.71.42.31.1-1.6-0.1-1.6
Patch foraging water rate 0 sec1.14.39.12.5-2.61.93.01.8-2.42.41.1-1.5-2.6-1.21.70.22.2
Patch foraging water rate 12 sec0.20.83.30.7-0.80.91.10.8-0.40.41.4-0.9-0.6-0.9-0.00.61.8
Patch foraging water rate 18 sec0.40.91.80.7-0.61.20.81.3-0.0-0.01.3-1.3-0.2-1.4-0.61.11.3
Patch foraging water rate 24 sec0.50.81.30.9-1.11.00.91.1-0.80.71.0-1.0-1.1-1.00.30.60.3
Patch foraging water rate 6 sec1.82.65.51.7-1.22.01.72.0-0.30.22.3-2.2-0.8-2.2-0.71.91.0
Seeking ratio, delayed vs. immediate footshock1.31.84.8-1.31.6-2.2-1.1-2.11.0-0.9-0.11.90.81.8-0.1-1.10.5
Distance traveled before self-admin0.00.10.40.3-0.20.20.00.2-0.20.20.3-0.2-0.1-0.10.1-0.1-0.7
Distance traveled after self-admin0.40.82.4-1.00.5-1.0-1.1-1.00.3-0.2-0.61.00.61.00.2-0.9-1.6
Extensor digitorum longus weight1.45.512.32.9-2.53.52.23.1-1.41.32.1-3.2-1.9-3.0-0.02.2-0.2
Bone: elastic displacement1.01.33.6-1.41.2-1.2-0.9-1.30.6-0.6-1.11.20.81.1-0.1-1.21.9
Bone: elastic work0.60.82.6-0.1-0.1-0.20.3-0.5-0.70.7-1.40.7-0.40.81.1-1.51.6
Bone: endosteal estimation0.10.23.00.1-0.00.4-0.40.3-0.00.00.1-0.1-0.0-0.2-0.10.2-1.7
Bone: endosteal perimeter0.20.54.10.10.00.6-0.50.30.4-0.40.6-0.50.2-0.5-0.60.9-2.0
Epididymis fat weight0.20.92.6-1.31.1-0.7-1.6-0.81.1-1.1-0.30.71.00.6-0.8-0.2-1.1
Delta time in closed arm before/after self-admin0.40.41.1-0.10.20.70.10.70.5-0.51.1-0.70.1-0.9-0.90.90.3
Delta time in open arm before/after self-admin0.30.41.6-0.40.2-0.7-0.5-0.7-0.10.1-1.30.60.40.70.4-0.7-0.8
Diff in mean of infusions in LGA sessions0.40.81.7-0.91.3-0.7-1.0-0.71.3-1.30.30.51.10.3-1.10.10.2
Delay discount exponential model param0.81.13.31.0-1.1-0.00.6-0.1-1.61.6-1.20.2-0.90.41.8-1.1-0.7
Extinction: sum of active levers before priming0.50.72.3-0.40.3-1.20.1-1.0-0.10.1-0.71.1-0.01.20.6-1.51.1
Active lever presses in extinction session 60.50.52.61.1-0.20.61.30.60.0-0.10.1-0.60.3-0.6-0.40.41.6
Bone: final force0.30.51.41.2-0.91.00.70.6-0.80.8-0.1-0.5-0.7-0.50.50.4-0.6
Bone: final moment0.40.61.61.2-1.01.00.80.6-1.01.0-0.1-0.5-0.9-0.40.80.2-0.5
Food consumed during 24 hour testing period1.32.75.4-2.32.3-1.8-2.1-1.81.8-1.80.11.71.51.4-1.1-0.70.7
Glucose0.10.20.4-0.50.3-0.6-0.2-0.50.3-0.20.40.60.40.5-0.1-0.40.5
Heart weight1.01.64.02.0-1.71.11.71.2-1.51.50.5-1.0-1.5-0.81.10.20.5
Delay discount hyperbolic model param0.91.13.30.9-1.1-0.10.6-0.2-1.61.6-1.30.2-0.90.51.8-1.2-0.5
Intermittent access intake day 1-15 change0.20.92.30.7-0.21.21.11.2-0.10.01.5-1.2-0.5-1.3-0.51.00.9
Intermittent access intake escalation0.21.02.50.8-0.41.21.31.3-0.20.21.6-1.2-0.6-1.3-0.41.01.0
Intermittent access intake escalation 20.20.32.00.40.0-0.00.8-0.1-0.30.30.30.1-0.60.10.4-0.31.4
Intermitt. access day 1 inactive lever presses0.00.33.2-0.3-0.1-0.00.40.40.2-0.2-0.2-0.30.5-0.3-0.30.31.8
Intermitt. access day 15 inactive lever presses0.31.43.60.0-0.01.30.31.40.6-0.71.6-1.41.0-1.6-1.41.90.4
Intermitt. access escalation Index0.10.31.4-0.40.9-0.50.1-0.30.7-0.7-0.10.20.60.1-0.60.11.2
Intermittent access day 1 total infusions0.51.42.70.7-1.61.41.31.4-1.51.51.0-1.1-1.2-1.00.9-0.2-0.7
Intermittent access day 15 total infusions0.81.94.00.9-1.01.91.61.9-0.70.62.0-1.7-0.9-1.9-0.21.10.9
Intermittent access terminal intake (last 3 days)1.11.93.61.1-1.21.91.51.9-0.90.91.9-1.7-1.2-1.80.11.10.8
Intermittent access total infusions2.32.74.81.5-1.72.22.02.2-1.41.41.6-1.9-1.7-1.90.51.00.8
Intermittent access day 1 locomotion0.30.51.50.0-0.8-0.30.7-0.0-1.11.1-0.50.2-0.90.31.2-1.1-0.2
Intermittent access day 15 total locomotion0.10.30.6-0.2-0.50.40.60.6-0.60.60.8-0.5-0.7-0.60.4-0.3-0.5
Intermittent access total locomotion1.31.63.30.8-1.61.21.61.3-1.61.61.0-1.0-1.8-1.01.1-0.3-0.3
Intermittent access standard deviation0.00.21.3-0.30.40.1-0.1-0.10.3-0.30.40.00.0-0.1-0.30.41.1
Left kidney weight1.814.429.05.4-5.13.64.63.6-4.94.91.2-2.9-4.6-2.33.60.1-0.2
Right kidney weight1.913.626.25.1-4.93.74.83.7-4.54.41.5-3.2-4.5-2.63.10.40.9
Cocaine induced anxiety0.30.82.4-0.60.50.5-0.30.51.0-1.10.7-0.60.7-0.8-1.41.60.9
Post-drug Anxiety0.40.41.4-0.50.30.5-0.20.50.7-0.70.5-0.50.8-0.6-1.01.2-0.2
Baseline Anxiety0.40.75.2-0.40.0-0.6-0.6-0.7-0.40.4-0.60.70.10.80.8-1.2-2.3
Tail length0.10.61.11.1-0.90.70.90.8-0.70.70.8-0.7-0.5-0.70.40.4-0.9
Length with tail0.21.12.71.4-1.11.71.21.4-0.70.70.8-1.3-0.6-1.30.10.90.0
Length without tail0.63.07.61.8-1.52.81.62.4-0.50.41.6-2.4-0.9-2.4-0.62.10.8
Times rat made contact with spout0.20.20.90.5-0.2-0.2-0.0-0.2-0.40.4-0.60.2-1.00.30.6-0.6-0.3
Lifetime Intake1.82.23.91.3-1.72.01.81.9-1.51.41.4-1.6-1.7-1.60.70.60.5
Liver weight, left0.91.53.51.3-1.50.71.50.7-1.91.9-0.2-0.3-1.3-0.11.8-0.91.2
Liver weight, right1.01.72.91.6-1.61.61.41.7-1.31.31.2-1.3-1.3-1.20.70.60.7
Locomotor activity0.50.81.71.2-1.30.81.10.7-1.31.30.5-0.6-1.0-0.41.1-0.10.2
Locomotor testing distance0.30.71.81.1-1.00.81.30.6-0.90.81.0-0.6-0.7-0.50.60.41.1
Locomotor testing rearing1.34.98.32.8-2.82.42.92.4-2.32.32.2-2.1-2.4-1.91.31.00.9
Locomotion in novel chamber0.10.20.4-0.30.6-0.4-0.5-0.40.6-0.60.50.30.30.3-0.50.2-0.1
Locomotion in novel chamber post-restriction0.41.14.3-1.31.2-1.1-0.7-1.01.0-1.0-0.61.01.20.8-0.6-0.22.1
Fecal boli incidents, locomotor time 10.00.10.50.1-0.10.00.30.0-0.10.10.10.0-0.40.00.1-0.30.7
Change in fecal boli incidents, locomotor task0.60.61.3-1.10.8-0.4-0.9-0.30.9-0.90.60.21.20.1-0.80.4-1.2
Time >=10cm from walls, locomotor time 10.30.41.00.5-0.30.91.00.9-0.00.0-0.0-0.8-0.4-0.9-0.30.60.6
Bouts of movement, locomotor time 11.11.43.3-1.81.4-0.6-1.6-0.51.6-1.60.50.51.80.3-1.40.40.1
Total resting periods, locomotor time 11.61.84.1-1.91.6-0.6-1.6-0.51.9-1.90.70.42.00.2-1.80.60.4
Rest time, locomotor task time 10.20.30.9-0.80.4-0.1-0.80.00.5-0.50.50.00.9-0.1-0.50.1-0.9
Distance moved, locomotor task time 10.41.12.50.7-0.6-0.50.9-0.6-1.01.0-1.60.6-1.30.81.3-1.11.5
Vertical activity count, locomotor time 10.21.23.20.20.2-1.30.2-1.4-0.30.4-1.81.3-0.61.41.0-1.51.6
Time >=10cm from walls, locomotor time 20.10.31.2-0.2-0.1-0.40.5-0.6-0.40.4-0.50.7-0.10.70.8-0.51.1
Bouts of movement, locomotor time 21.03.27.6-1.82.5-1.0-1.7-0.92.8-2.80.00.72.70.4-2.50.71.2
Total resting periods, locomotor time 20.72.96.8-1.82.3-1.0-1.6-0.92.6-2.60.00.72.60.5-2.30.61.1
Rest time, locomotor task time 20.30.52.2-0.90.2-0.8-0.9-0.60.1-0.0-0.10.70.80.70.3-0.6-1.5
Distance moved, locomotor task time 20.91.13.11.1-0.90.21.4-0.0-1.21.2-1.2-0.0-1.50.11.3-0.81.8
Vertical activity count, locomotor time 20.30.89.00.60.4-0.30.7-0.50.2-0.2-0.80.3-0.30.3-0.1-0.03.0
Light reinforcement 10.10.30.90.9-0.80.50.90.3-0.70.70.4-0.4-0.7-0.30.5-0.1-0.4
Light reinforcement 20.20.30.91.0-0.20.80.90.50.0-0.1-0.4-0.6-0.1-0.6-0.30.60.8
Bone: marrow area0.10.22.80.2-0.10.4-0.30.3-0.10.10.0-0.1-0.1-0.1-0.00.1-1.7
Bone: maximum diameter1.12.24.52.1-1.81.71.41.7-1.31.21.0-1.8-1.4-1.60.51.0-1.8
Bone: maximum force0.20.31.00.7-0.71.00.50.6-0.50.50.4-0.5-0.5-0.50.20.4-0.5
Bone: maximum moment0.20.41.00.8-0.81.00.60.5-0.70.70.4-0.5-0.6-0.40.50.3-0.3
Mean time between licks in bursts0.10.52.8-0.20.3-0.70.2-0.7-0.10.2-0.50.7-0.80.70.5-0.91.7
Mean num. licks in bursts0.61.63.8-1.91.1-1.6-1.4-1.60.4-0.3-1.21.70.71.60.4-1.60.6
Cd content in liver0.20.30.70.6-0.30.80.40.6-0.0-0.00.3-0.7-0.4-0.7-0.30.8-0.0
Co content in liver1.11.34.2-1.01.2-1.4-0.9-1.50.5-0.5-2.01.50.71.40.2-1.2-0.1
Cu content in liver0.40.53.70.7-0.30.50.10.60.1-0.1-0.1-0.7-0.2-0.7-0.40.7-1.9
Fe content in liver2.73.46.22.2-1.81.91.52.4-0.90.82.5-2.4-0.9-2.3-0.21.8-2.1
K content in liver0.30.31.0-0.10.1-0.7-0.1-0.6-0.10.1-1.00.5-0.10.60.4-0.7-0.8
Mg content in liver0.80.93.50.3-0.4-0.60.3-0.6-0.90.9-1.90.6-0.80.81.2-1.4-1.1
Mn content in liver3.84.211.40.5-1.1-1.30.7-1.3-2.42.5-3.21.7-1.72.13.4-3.1-0.1
Na content in liver0.30.33.80.2-0.20.0-0.3-0.0-0.20.2-0.60.0-0.30.10.2-0.5-1.9
Rb content in liver0.30.43.60.6-0.40.30.30.4-0.20.2-0.4-0.6-0.4-0.5-0.0-0.3-1.9
Se content in liver1.11.32.81.6-1.50.41.70.6-1.61.6-0.5-0.4-1.4-0.21.5-0.30.0
Sr content in liver0.30.20.7-0.30.1-0.7-0.2-0.5-0.20.3-0.80.6-0.10.70.6-0.6-0.0
Zn content in liver0.50.61.60.8-1.00.50.60.6-0.80.8-0.4-0.6-1.1-0.40.6-0.1-1.3
Bone: minimum diameter0.20.41.70.5-0.80.90.30.7-0.50.50.8-0.7-0.4-0.60.20.2-1.3
Time in familiar zone, hab. session 10.30.31.60.5-0.50.50.60.5-0.30.30.4-0.5-0.5-0.50.10.21.3
Time in novel zone, hab. session 10.50.50.90.9-1.00.60.70.6-0.90.90.5-0.5-1.0-0.40.70.1-0.9
Total zone transitions, hab. session 10.30.41.00.8-0.61.00.60.8-0.50.50.4-0.8-0.7-0.80.10.40.7
Total locomotion distance, hab. session 10.30.40.9-0.90.9-0.6-0.9-0.50.7-0.7-0.10.40.80.3-0.5-0.20.8
Locomotion velocity, hab. session 10.71.02.1-1.41.4-0.8-1.2-0.81.2-1.2-0.20.71.30.4-0.9-0.21.2
Time in familiar zone, hab. session 21.21.32.70.6-0.41.51.01.40.3-0.31.7-1.5-0.1-1.6-1.01.51.4
Time in novel zone, hab. session 20.20.21.80.1-0.2-0.3-0.4-0.2-0.30.3-0.30.3-0.40.40.4-0.3-1.3
Total zone transitions, hab. session 20.50.61.90.6-0.70.21.00.1-1.01.0-1.4-0.0-1.00.11.0-0.80.8
Total locomotion distance, hab. session 20.60.82.0-0.90.9-1.0-0.7-1.00.6-0.5-1.40.90.60.8-0.1-0.81.1
Locomotion velocity, hab. session 20.50.72.3-0.90.8-1.0-0.5-0.90.3-0.3-1.50.90.40.90.2-1.01.1
Novel to familiar place preference ratio0.81.11.61.3-1.31.11.11.1-1.11.11.1-1.0-1.2-0.90.70.6-0.3
Novelty place preference0.81.01.61.2-1.31.01.11.0-1.11.11.0-0.9-1.3-0.80.70.4-0.1
Time in novel zone, NPP test1.11.42.21.5-1.51.11.41.2-1.31.31.3-1.0-1.5-1.00.80.50.1
Total zone transitions, NPP test0.10.10.30.3-0.20.50.20.40.0-0.0-0.5-0.5-0.1-0.5-0.20.2-0.0
Total locomotion distance, NPP test0.30.41.30.4-0.20.70.40.80.0-0.10.5-0.9-0.2-0.9-0.50.71.1
Locomotion velocity, NPP test0.20.20.90.20.00.40.20.50.2-0.20.1-0.70.1-0.7-0.50.50.9
Intraocular pressure0.30.61.70.7-0.40.80.21.00.0-0.10.7-1.0-0.3-1.1-0.61.3-0.9
Delta distance traveled before/after self-admin1.21.42.8-1.71.4-1.2-1.5-1.41.3-1.2-0.71.21.21.1-0.7-0.5-0.5
Delta ambulatory time before/after self-admin0.30.51.0-1.00.7-0.8-0.8-1.00.5-0.4-0.81.00.40.9-0.0-0.9-0.2
Parametrial fat weight0.10.30.80.1-0.3-0.50.2-0.3-0.60.7-0.80.4-0.70.50.9-0.9-0.2
Pavlov. Cond. lever latency0.30.41.1-0.90.60.4-1.0-0.10.7-0.70.4-0.00.4-0.2-0.80.6-1.0
Pavlov. Cond. magazine entry latency0.40.50.90.8-0.30.80.80.90.1-0.10.4-1.0-0.4-1.0-0.50.80.7
Pavlov. Cond. change in total contacts0.40.41.4-0.40.7-1.2-0.0-0.80.4-0.4-0.50.80.60.80.0-0.50.8
Pavlov. Cond. index score0.20.31.30.8-0.4-0.01.00.3-0.40.4-0.4-0.2-0.5-0.10.4-0.21.1
Pavlov. Cond. latency score0.10.20.90.4-0.0-0.40.6-0.1-0.10.1-0.60.1-0.10.20.2-0.40.9
Pavlov. Cond. lever contacts0.20.20.90.7-0.3-0.30.80.1-0.50.5-0.2-0.0-0.30.10.5-0.51.0
Pavlov. Cond. magazine entry number0.20.20.6-0.60.1-0.3-0.7-0.5-0.10.10.00.50.20.50.3-0.4-0.8
Pavlov. Cond. intertrial magazine entries0.40.51.60.1-0.6-0.30.6-0.3-1.01.00.00.6-0.50.71.3-0.80.7
Pavlov. Cond. lever-magazine prob. diff.0.40.52.60.8-0.5-0.21.20.1-0.60.6-0.90.0-0.60.20.7-0.61.6
Pavlov. Cond. response bias0.70.82.21.5-1.00.81.51.1-0.70.70.3-1.0-0.9-0.90.20.50.8
Pavlov. Cond. lever latency0.10.21.2-0.50.2-0.3-0.5-0.30.1-0.1-0.60.30.10.30.1-0.4-1.1
Pavlov. Cond. magazine entry latency1.31.83.91.3-1.12.01.11.9-0.50.41.8-1.7-1.1-1.8-0.41.50.7
Pavlov. Cond. change in total contacts0.10.30.90.3-0.20.70.40.60.3-0.30.9-0.6-0.2-0.7-0.60.71.0
Pavlov. Cond. index score0.61.02.50.9-0.61.40.91.3-0.0-0.01.6-1.2-0.5-1.3-0.61.21.0
Pavlov. Cond. latency score0.50.82.10.7-0.41.20.61.10.1-0.11.4-1.0-0.3-1.1-0.61.10.9
Pavlov. Cond. lever contacts0.30.41.00.8-0.40.80.70.7-0.10.11.0-0.8-0.3-0.7-0.30.70.9
Pavlov. Cond. magazine entry number1.51.94.1-0.80.3-1.8-0.6-1.7-0.50.6-2.01.70.22.01.5-2.0-1.1
Pavlov. Cond. intertrial magazine entries0.71.56.2-1.00.5-1.3-1.3-1.30.00.0-1.31.20.41.40.6-1.6-2.5
Pavlov. Cond. lever-magazine prob. diff.0.71.12.31.0-0.71.50.91.3-0.20.21.5-1.2-0.6-1.3-0.41.11.0
Pavlov. Cond. response bias0.30.41.10.8-0.40.80.70.7-0.20.10.9-0.7-0.4-0.7-0.20.71.0
Time in closed arm before self-admin0.50.92.21.5-0.91.21.21.1-0.70.70.6-1.1-0.9-1.00.30.50.4
Time in closed arm after self-admin1.51.74.5-0.30.81.2-0.00.91.5-1.61.6-1.10.7-1.4-2.11.71.5
Time in open arm before self-admin0.70.92.2-1.30.8-1.5-0.8-1.20.6-0.6-0.31.30.81.2-0.1-0.9-0.2
Time in open arm after self-admin2.73.07.4-1.20.4-2.4-0.9-2.2-0.50.6-2.72.30.52.41.6-2.6-1.0
Bone: periosteal estimation0.30.73.41.0-0.81.00.30.9-0.60.60.4-0.8-0.6-0.70.20.5-1.8
Bone: periosteal perimeter0.30.64.20.6-0.50.90.10.7-0.20.10.8-0.8-0.2-0.8-0.20.8-2.1
Bone: post-yield work0.50.92.2-0.90.90.1-0.9-0.11.3-1.31.0-0.20.9-0.4-1.50.9-1.4
Progressive ratio test 1 active lever presses0.81.43.60.6-1.60.61.40.7-1.91.90.2-0.3-1.2-0.11.8-1.00.4
Progressive ratio test 1 breakpoint0.71.33.40.6-1.50.41.30.5-1.81.90.1-0.2-1.30.01.8-1.10.3
Progressive ratio test 1 inactive lever presses0.51.43.11.0-1.41.41.61.8-1.01.01.4-1.4-0.5-1.40.30.60.3
Progressive ratio test 2 active lever presses1.31.83.61.0-1.41.81.41.9-1.11.11.6-1.7-1.0-1.70.31.00.1
Progressive ratio test 2 breakpoint1.62.04.01.2-1.51.91.52.0-1.21.11.6-1.8-1.1-1.80.31.10.1
Progressive ratio test 2 inactive lever presses0.20.61.5-0.2-0.31.00.51.20.0-0.11.0-1.10.6-1.2-0.60.90.7
Incentive Sensitization - Responses1.02.86.01.6-1.12.31.42.5-0.50.42.1-2.4-0.7-2.4-0.72.10.1
Incentive Sensitization - Breakpoint1.22.76.01.5-1.02.31.42.4-0.40.32.0-2.4-0.6-2.5-0.82.20.2
Sum of active levers in priming session hrs 5-60.60.61.4-0.40.5-1.1-0.1-1.10.2-0.1-0.41.20.01.20.3-1.11.2
Progressive ratio0.61.83.9-1.31.5-0.4-1.5-0.21.8-1.82.00.01.4-0.3-1.81.5-1.2
Food seeking constrained by brief footshock4.35.411.8-2.42.3-3.4-2.5-3.31.5-1.3-2.33.11.43.00.0-2.30.2
Seeking ratio, punishment vs. effort1.02.28.7-0.80.5-1.7-0.4-1.8-0.00.1-3.01.70.21.80.9-2.31.8
Retroperitoneal fat weight0.20.71.90.6-0.20.8-0.21.00.5-0.50.8-1.00.3-1.1-1.01.3-1.4
Reaction time number correct1.55.410.32.9-3.22.33.12.4-2.72.61.2-1.9-2.9-1.71.80.61.7
Reaction time mean minus median0.00.20.60.40.10.40.40.60.3-0.30.6-0.50.1-0.6-0.50.80.2
Reaction time mean minus median AUC0.11.02.01.3-0.61.21.11.4-0.20.11.2-1.3-0.6-1.3-0.41.3-0.2
Reaction time num false alarms2.74.610.73.3-2.52.72.82.5-2.01.91.2-2.3-2.1-2.10.91.40.6
Reaction time num false alarms AUC1.63.89.03.0-2.22.42.72.2-1.81.70.9-2.0-1.9-1.80.91.20.9
Reaction time trials correct on left1.55.410.32.9-3.22.33.12.4-2.72.61.2-1.9-2.9-1.71.80.61.7
Reaction time trials on left1.65.510.33.0-3.22.33.12.4-2.72.61.1-1.9-2.9-1.71.80.61.7
Reaction time mean0.10.30.6-0.40.8-0.6-0.5-0.30.7-0.7-0.10.50.60.4-0.50.10.3
Reaction time mean AUC0.10.20.5-0.30.7-0.5-0.4-0.20.6-0.6-0.10.30.60.3-0.50.10.2
Median of all reaction times0.30.50.9-0.60.9-0.9-0.8-0.70.7-0.7-0.40.80.70.7-0.4-0.20.0
Reaction time omissions0.20.31.30.7-0.60.20.50.4-0.50.5-1.10.0-0.80.20.5-0.30.0
Reaction time false alarm rate0.20.30.80.9-0.10.80.60.7-0.0-0.00.4-0.7-0.0-0.7-0.30.80.0
Reaction time premature initiation rate0.50.72.5-0.70.9-1.0-0.3-1.00.4-0.4-1.10.90.60.90.1-1.01.6
Reaction time premature initiations0.30.95.30.8-0.80.21.30.2-0.90.9-0.6-0.1-0.80.00.9-0.62.3
Std. dev. reaction times0.00.10.40.20.40.00.20.30.4-0.40.2-0.10.2-0.2-0.50.50.6
Reaction time trials completed1.65.510.33.0-3.22.33.12.4-2.72.61.1-1.9-2.9-1.71.80.61.7
Reaction time trials AUC1.96.612.53.3-3.52.53.42.6-3.02.91.2-2.1-3.2-1.82.00.61.9
Run reversals in cocaine runway, females0.50.62.0-0.30.70.5-0.20.41.1-1.20.2-0.60.7-0.7-1.41.20.3
Run reversals in cocaine runway, males0.50.51.70.8-0.90.10.30.1-1.01.00.00.1-1.30.21.0-0.3-0.9
Latency to leave start box in cocaine runway1.01.45.60.8-0.31.40.51.50.2-0.32.4-1.5-0.2-1.6-0.91.80.5
Latency to leave start box in cocaine runway, F0.50.71.71.1-0.70.91.10.9-0.60.51.3-0.9-0.6-0.80.20.80.7
Latency to leave start box in cocaine runway, M1.41.44.10.20.11.3-0.21.40.7-0.82.0-1.40.2-1.6-1.51.90.1
Std. dev. time between licks in bursts0.20.32.8-0.0-0.20.10.70.1-0.30.3-0.5-0.00.3-0.00.3-0.21.7
Total sessions with >9 infusions1.92.44.71.4-2.21.21.91.3-2.22.20.8-1.0-2.1-0.81.7-0.7-0.4
Short access day 1 total inactive lever presses0.40.92.01.1-0.61.21.11.4-0.20.20.8-1.4-0.6-1.4-0.41.00.7
Short access day 10 total inactive lever presses0.10.92.2-0.31.1-0.7-0.6-0.31.5-1.5-0.60.21.10.1-1.40.51.4
Short access day 1 total infusions0.61.32.61.0-1.60.81.30.9-1.61.60.4-0.6-1.5-0.51.3-0.9-0.7
Short access day 10 total infusions1.52.55.21.4-2.31.41.71.4-2.32.20.7-1.0-2.3-0.81.8-0.4-0.1
Short access total infusions1.01.43.20.9-1.71.01.21.0-1.81.80.4-0.7-1.8-0.51.5-0.7-0.5
Short access day 1 locomotion1.52.55.21.9-2.11.32.11.5-2.02.01.0-1.1-2.3-1.01.5-0.5-0.5
Short access day 10 total locomotion0.20.92.40.4-0.3-1.00.5-0.7-0.90.9-1.20.8-1.21.01.3-1.50.3
Short access total locomotion1.21.84.90.3-1.1-0.61.1-0.5-1.81.9-0.90.7-1.81.02.2-2.00.6
One hour access (0.3 mA shock)0.70.81.90.1-0.31.20.51.30.2-0.21.4-1.20.3-1.4-0.80.90.9
Compulsive drug intake0.20.30.5-0.0-0.5-0.40.70.1-0.70.7-0.4-0.00.60.10.7-0.50.5
One hour access (shock baseline)0.82.04.61.4-1.22.11.41.9-0.70.61.7-1.8-1.3-1.9-0.21.20.9
Social response proportion1.31.62.91.7-1.71.31.51.6-1.21.20.3-1.2-1.4-1.10.60.61.5
Social responses0.70.91.71.1-1.30.91.31.0-1.00.91.0-0.9-1.0-0.80.50.41.1
Social time1.72.75.4-2.32.2-1.5-1.8-1.52.2-2.2-0.11.02.10.8-1.80.20.8
Soleus weight1.02.87.70.8-0.42.50.22.00.8-0.91.9-2.40.2-2.5-1.92.8-0.4
Bone: stiffness0.71.32.71.2-1.11.60.71.5-0.50.41.4-1.5-0.6-1.5-0.21.3-0.7
Tibialis anterior weight2.27.716.53.5-3.24.12.73.6-2.01.82.4-3.7-2.6-3.40.32.3-0.1
Time to tail flick, vehicle, before self-admin1.92.36.81.1-1.80.11.3-0.1-2.32.4-1.20.4-1.90.72.6-1.40.9
Time to tail flick, vehicle, after self-admin1.02.15.80.8-0.21.80.41.80.7-0.72.4-1.9-0.3-2.1-1.62.1-0.1
Time to tail flick, test, before self-admin2.22.66.2-0.80.6-2.1-0.8-2.2-0.30.4-2.52.2-0.32.31.4-2.50.4
Time to tail flick, test, after self-admin0.30.31.7-0.50.3-0.4-1.0-0.50.3-0.30.60.50.20.4-0.10.3-1.3
Delta time to tail flick, vehicle, before/after SA0.70.71.70.00.30.8-0.30.90.8-0.81.3-1.00.3-1.2-1.31.1-0.5
Delta time to tail flick, test, before/after SA1.11.43.50.9-0.91.50.41.5-0.40.31.9-1.4-0.3-1.4-0.31.7-1.6
Tibia length0.20.61.21.0-0.90.40.40.2-1.11.1-1.1-0.0-0.70.21.1-0.5-0.3
Ambulatory time before self-admin0.00.10.70.10.10.1-0.10.10.2-0.20.6-0.20.3-0.2-0.30.1-0.8
Ambulatory time after self-admin0.40.61.3-1.00.7-0.9-0.9-0.90.6-0.6-0.20.80.90.8-0.3-0.8-1.1
Bone: tissue strength0.50.51.5-0.80.6-0.9-0.3-1.20.2-0.2-0.01.10.31.10.3-0.40.6
Total heroin consumption0.10.20.90.50.2-0.30.5-0.20.1-0.10.50.2-0.50.2-0.1-0.31.0
Bone: trabecular number0.00.00.20.00.00.00.20.20.2-0.20.2-0.10.5-0.1-0.30.00.2
Bone: trabecular spacing0.00.10.4-0.1-0.0-0.1-0.1-0.1-0.20.2-0.00.1-0.40.10.3-0.1-0.6
Bone: trabecular thickness0.81.12.61.6-1.51.11.51.1-1.21.20.3-1.0-1.0-0.90.70.1-0.2
Bone: trabecular tissue density0.30.51.21.1-0.60.80.90.9-0.50.40.6-0.9-0.6-0.90.10.80.2
Water consumed over 24 hours0.61.23.10.4-0.2-1.0-0.1-1.0-0.80.9-1.81.2-1.11.41.4-1.70.3
Number of responses in last shaping day2.02.66.02.4-2.01.72.11.8-1.61.61.7-1.5-1.9-1.50.90.40.0