Hub : Genes

Zmat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Zmat3 0.01 0.01 4.2e-03 0.02 0.01 0.01 0.01 6.7e-04 6.6e-03 1.9e-02 1.0e-02
2 pVTA gene expression Zmat3 0.04 0.03 8.5e-04 0.04 0.03 0.03 0.03 3.0e-04 1.3e-03 1.8e-03 8.6e-04
3 BLA gene expression Zmat3 0.15 0.08 1.4e-08 0.11 0.13 0.09 0.15 2.6e-06 2.5e-07 2.5e-05 3.1e-08
4 LHb gene expression Zmat3 0.11 0.07 3.1e-03 0 -0.01 -0.01 -0.01 2.7e-01 7.0e-01 9.6e-01 7.4e-01
5 IC gene expression Zmat3 0.11 0.07 4.6e-04 0.03 0.06 0.03 0.04 1.5e-02 1.3e-03 1.5e-02 9.0e-03
6 Brain gene expression Zmat3 0.05 0.03 3.6e-05 0.05 0.04 0.04 0.04 3.2e-05 1.3e-04 1.5e-04 1.7e-04
7 PL gene expression Zmat3 0.06 0.04 1.1e-05 0.05 0.04 0.04 0.04 1.4e-06 1.1e-05 2.0e-05 1.4e-05
8 NAcc intron excision ratio chr2_117061055_117065112 0.01 0.01 7.5e-03 0.01 0 -0 0 3.7e-02 1.8e-01 7.3e-01 2.2e-01
9 OFC gene expression Zmat3 0.17 0.11 5.6e-03 0.06 0.08 0 0.06 1.6e-02 5.2e-03 3.2e-01 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.13.66.5-2.4-2.5-2.4-2.3-2.0-1.3-1.31.2-0.6
Area under the delay curve0.91.11.4-1.1-1.0-1.1-1.1-1.1-1.2-0.90.9-0.8
BMI with tail0.72.54.4-1.0-1.0-1.1-1.2-1.6-1.8-2.12.1-1.8
BMI without tail0.51.62.1-1.0-1.2-1.1-1.1-1.4-1.2-1.51.4-1.4
Body weight0.10.61.5-0.4-0.4-0.6-0.7-0.8-0.6-1.21.2-0.8
Weight adjusted by age1.92.95.31.11.11.31.41.81.72.3-2.31.9
Bone surface0.10.20.5-0.5-0.6-0.4-0.3-0.10.50.1-0.10.7
Bone volume0.20.41.0-0.7-0.8-0.6-0.5-0.10.60.3-0.41.0
Breakpoint value in progressive ratio session1.82.22.7-1.6-1.6-1.6-1.6-1.7-1.5-1.21.2-1.1
Number of licking bursts1.52.43.9-1.2-1.3-1.1-1.0-1.7-2.0-1.71.7-2.0
Context. condit. distance diff. score2.83.46.8-2.3-2.3-2.5-2.6-1.9-0.9-1.11.1-0.2
Locomotion velocity, session 11.01.12.41.51.41.31.10.5-0.3-0.80.8-1.1
Locomotion distance, session 10.60.71.60.90.70.70.7-0.1-0.6-1.11.1-1.3
Locomotion velocity, session 21.61.93.71.91.81.91.90.9-0.3-0.20.2-1.2
Locomotion distance, session 20.60.81.81.31.21.31.30.70.1-0.10.1-0.5
Locomotion velocity, session 30.00.00.10.20.00.10.1-0.10.0-0.40.4-0.3
Locomotion distance, session 30.20.20.50.70.50.60.70.30.00.1-0.1-0.4
Stereotopy head waving bouts, day 30.00.00.10.20.30.20.10.2-0.20.3-0.30.1
Stereotopy head waving duration, day 30.60.81.0-1.0-0.9-1.0-1.0-0.9-1.0-0.70.7-0.6
Locomotion velocity, session 70.80.91.20.80.70.91.01.11.10.9-0.90.9
Locomotion distance, session 70.91.11.50.90.91.01.01.11.21.1-1.11.0
Stereotopy head waving bouts, day 71.11.22.5-0.6-0.7-0.6-0.6-1.1-1.4-1.41.4-1.6
Stereotopy head waving duration, day 72.02.43.4-1.2-1.2-1.2-1.2-1.7-1.7-1.91.9-1.8
Locomotion velocity, session 82.42.94.2-1.5-1.5-1.5-1.4-1.8-2.0-1.81.8-1.7
Locomotion distance, session 80.60.81.6-0.9-1.0-1.1-1.3-0.9-0.3-0.90.9-0.1
Degree of sensitization distance1.71.73.00.80.90.90.81.41.71.6-1.61.7
Degree of sensitization stereotypy2.72.93.9-1.4-1.5-1.4-1.3-1.9-1.8-2.02.0-2.0
Conditioned locomotion0.30.30.9-0.1-0.1-0.3-0.30.30.80.7-0.70.9
Cocaine response after cond. corrected0.10.20.60.10.20.1-0.00.40.40.6-0.50.8
Cocaine response after cond. not corrected0.40.50.90.60.70.60.50.80.90.7-0.60.9
Cocaine response before conditioning0.00.10.30.10.10.10.10.10.6-0.20.20.0
Saline control response0.30.41.10.50.50.30.20.71.00.6-0.50.9
Bone: connectivity density1.52.33.3-1.8-1.8-1.8-1.7-1.7-1.1-1.31.3-1.0
Bone: cortical apparent density0.00.10.1-0.3-0.3-0.3-0.3-0.20.20.1-0.00.1
Bone: cortical area0.81.23.6-0.1-0.1-0.2-0.20.71.91.3-1.31.9
Bone: cortical porosity0.10.10.2-0.2-0.3-0.2-0.20.0-0.20.4-0.50.4
Bone: cortical porosity0.20.20.5-0.2-0.3-0.3-0.30.10.10.6-0.60.7
Bone: cortical thickness0.50.82.4-0.5-0.5-0.6-0.70.31.50.9-0.91.5
Bone: cortical thickness0.20.30.70.50.50.30.3-0.1-0.6-0.50.5-0.9
Bone: cortical tissue density0.00.10.1-0.3-0.3-0.3-0.3-0.20.10.0-0.00.0
Condit. Reinf. active minus inactive responses1.41.62.41.51.41.51.51.41.10.9-0.90.7
Condit. Reinf. active-inactive response ratio1.51.62.11.41.31.31.31.41.41.1-1.11.1
Condit. Reinf. active responses0.60.81.51.11.01.21.20.90.70.5-0.50.3
Condit. Reinf. inactive responses0.20.20.4-0.3-0.3-0.1-0.0-0.4-0.5-0.60.6-0.6
Incentive salience index mean1.41.72.71.71.61.71.61.51.20.8-0.80.6
Condit. Reinf. lever presses0.40.51.01.01.01.00.90.70.4-0.10.1-0.1
Condit. Reinf. active minus inactive responses1.11.41.81.11.01.21.21.31.31.1-1.11.1
Condit. Reinf. active-inactive response ratio1.21.41.71.11.01.01.01.31.31.2-1.21.2
Condit. Reinf. active responses2.12.94.31.91.82.02.11.91.61.3-1.31.1
Condit. Reinf. inactive responses0.91.12.51.41.41.51.60.90.40.2-0.2-0.3
Condit. Reinf. lever presses0.40.50.90.60.50.80.90.80.90.6-0.60.7
Condit. Reinf. lever reinforcers received2.02.74.01.81.72.02.01.91.61.2-1.21.1
Conditioned reinforcement - actives0.20.40.90.91.00.80.70.60.00.5-0.5-0.1
Conditioned reinforcement - inactives0.00.00.10.20.30.10.10.0-0.40.1-0.1-0.2
Conditioned locomotion0.30.41.00.91.00.80.80.4-0.20.2-0.1-0.4
Patch foraging indifference point 0 sec0.81.42.5-1.4-1.6-1.2-1.0-1.4-1.4-0.70.7-1.0
Patch foraging indifference point AUC2.73.97.4-1.3-1.1-1.1-1.1-2.0-2.2-2.72.7-2.5
Delay disc. indifference point, 0s delay0.20.20.40.40.60.60.50.50.30.1-0.20.2
Delay disc. indifference point, 16s delay0.91.01.9-1.2-1.3-1.4-1.4-1.0-0.9-0.20.4-0.2
Delay disc. indifference point, 2s delay0.80.91.3-1.1-0.8-0.9-0.9-1.0-0.8-1.11.0-0.6
Delay disc. indifference point, 24s delay0.80.81.9-1.1-1.2-1.4-1.4-0.9-0.5-0.00.2-0.1
Delay disc. indifference point, 4s delay0.60.71.4-0.8-0.4-0.5-0.6-0.8-1.2-1.00.9-0.9
Delay disc. indifference point, 8s delay0.30.30.8-0.4-0.4-0.4-0.4-0.6-0.9-0.60.5-0.7
Indifference point function ln k1.83.15.81.21.01.11.11.81.82.4-2.42.2
Indifference point function log k1.83.15.81.21.01.11.11.81.82.4-2.42.2
Patch foraging total patch changes 0 sec0.71.42.2-1.3-1.5-1.2-0.9-1.3-1.4-0.80.8-1.1
Patch foraging total patch changes 12 sec1.31.62.3-1.2-1.2-0.9-0.7-1.4-1.5-1.41.4-1.5
Patch foraging total patch changes 18 sec1.21.83.1-1.1-1.0-0.7-0.6-1.4-1.8-1.61.6-1.8
Patch foraging total patch changes 24 sec3.35.66.8-2.5-2.3-2.2-2.0-2.6-2.5-2.52.5-2.1
Patch foraging total patch changes 6 sec3.85.77.3-2.6-2.7-2.3-2.0-2.7-2.6-2.22.2-2.2
Patch foraging time to switch 0 sec0.20.40.70.30.30.20.20.50.80.8-0.80.8
Patch foraging water rate 0 sec0.30.50.9-0.9-1.0-0.7-0.5-0.8-0.7-0.70.7-0.5
Patch foraging water rate 12 sec0.20.41.2-0.1-0.10.00.20.40.31.1-1.10.9
Patch foraging water rate 18 sec0.20.30.70.50.50.70.80.4-0.30.4-0.4-0.1
Patch foraging water rate 24 sec0.91.22.1-1.3-1.5-1.2-1.0-1.2-1.3-0.70.7-0.7
Patch foraging water rate 6 sec0.00.00.1-0.2-0.2-0.10.1-0.0-0.10.3-0.30.1
Seeking ratio, delayed vs. immediate footshock0.50.61.7-0.7-0.7-1.0-1.3-0.30.50.4-0.40.7
Distance traveled before self-admin1.62.12.7-1.4-1.4-1.3-1.3-1.6-1.3-1.61.6-1.3
Distance traveled after self-admin0.30.40.9-0.5-0.6-0.3-0.1-0.7-0.9-0.60.6-1.0
Extensor digitorum longus weight0.31.33.4-0.4-0.5-0.5-0.5-1.1-0.7-1.81.8-1.5
Bone: elastic displacement0.30.31.0-0.1-0.0-0.2-0.30.30.41.0-1.00.8
Bone: elastic work2.02.65.40.80.80.70.61.61.82.3-2.32.3
Bone: endosteal estimation0.51.11.50.90.80.91.01.21.11.0-1.11.2
Bone: endosteal perimeter0.40.91.61.11.01.21.21.10.90.7-0.70.7
Epididymis fat weight0.10.30.50.50.70.70.60.40.3-0.40.4-0.1
Delta time in closed arm before/after self-admin0.80.81.7-0.9-1.0-1.2-1.3-0.8-0.2-0.80.80.1
Delta time in open arm before/after self-admin0.20.20.40.30.40.60.70.3-0.00.4-0.4-0.2
Diff in mean of infusions in LGA sessions0.10.10.4-0.4-0.3-0.3-0.20.10.30.4-0.40.7
Delay discount exponential model param1.21.31.71.21.11.21.31.21.31.1-1.10.9
Extinction: sum of active levers before priming2.22.54.00.71.01.21.31.71.92.0-2.01.9
Active lever presses in extinction session 60.20.20.3-0.5-0.5-0.5-0.5-0.4-0.4-0.10.1-0.2
Bone: final force0.61.02.60.50.40.40.31.01.61.2-1.21.5
Bone: final moment0.61.02.60.20.10.20.10.91.61.3-1.31.6
Food consumed during 24 hour testing period0.00.00.20.10.10.00.00.10.40.0-0.10.2
Glucose0.81.22.01.31.21.31.41.20.51.1-1.00.5
Heart weight0.10.10.2-0.2-0.2-0.2-0.4-0.3-0.2-0.40.4-0.3
Delay discount hyperbolic model param1.21.31.71.21.01.11.21.21.31.2-1.10.9
Intermittent access intake day 1-15 change0.51.11.5-1.0-1.0-0.9-0.9-1.2-1.2-1.11.1-1.1
Intermittent access intake escalation0.81.62.6-1.1-1.1-1.0-1.0-1.4-1.6-1.31.3-1.5
Intermittent access intake escalation 20.00.00.1-0.2-0.2-0.10.1-0.00.00.2-0.20.1
Intermitt. access day 1 inactive lever presses0.10.20.60.20.10.10.00.40.40.7-0.80.8
Intermitt. access day 15 inactive lever presses0.20.40.90.90.90.90.90.4-0.40.1-0.1-0.5
Intermitt. access escalation Index0.10.20.7-0.1-0.2-0.2-0.30.20.50.6-0.50.8
Intermittent access day 1 total infusions3.25.18.22.82.92.72.52.51.61.9-1.81.0
Intermittent access day 15 total infusions0.30.41.30.50.60.40.4-0.2-1.0-0.40.4-1.1
Intermittent access terminal intake (last 3 days)0.71.02.11.41.41.31.21.00.40.6-0.60.0
Intermittent access total infusions0.81.02.31.41.51.31.20.7-0.30.2-0.2-0.7
Intermittent access day 1 locomotion1.62.03.41.81.81.71.61.50.91.3-1.20.5
Intermittent access day 15 total locomotion0.20.31.0-0.2-0.1-0.1-0.1-0.5-1.0-0.40.5-0.9
Intermittent access total locomotion0.30.41.30.50.60.50.4-0.1-0.9-0.40.4-1.1
Intermittent access standard deviation0.10.20.4-0.6-0.5-0.5-0.4-0.5-0.5-0.30.3-0.3
Left kidney weight0.10.61.8-0.7-0.6-0.6-0.60.11.30.3-0.31.3
Right kidney weight0.41.93.2-1.7-1.8-1.7-1.6-1.4-0.8-1.31.3-0.4
Cocaine induced anxiety0.20.30.90.80.80.90.90.50.1-0.10.1-0.2
Post-drug Anxiety0.30.30.80.70.70.80.90.50.10.0-0.0-0.2
Baseline Anxiety0.00.00.1-0.1-0.1-0.1-0.1-0.1-0.2-0.10.1-0.2
Tail length0.00.10.50.30.20.20.30.30.70.2-0.20.2
Length with tail0.20.91.71.01.00.90.91.11.30.7-0.70.9
Length without tail0.00.10.30.40.50.40.30.40.30.1-0.10.4
Times rat made contact with spout0.91.01.61.21.21.21.21.10.80.9-0.90.4
Lifetime Intake1.11.32.91.71.71.61.51.0-0.10.4-0.4-0.5
Liver weight, left1.11.83.81.91.91.91.81.31.00.1-0.0-0.1
Liver weight, right0.20.30.70.40.40.50.40.60.70.5-0.50.9
Locomotor activity2.33.66.22.02.01.51.22.12.51.7-1.72.0
Locomotor testing distance1.42.54.61.81.71.41.21.82.11.3-1.31.5
Locomotor testing rearing0.40.71.90.50.40.20.10.81.41.0-1.11.2
Locomotion in novel chamber0.40.41.50.50.50.60.8-0.1-0.5-0.60.6-1.2
Locomotion in novel chamber post-restriction0.10.10.2-0.4-0.3-0.4-0.5-0.3-0.1-0.50.50.2
Fecal boli incidents, locomotor time 10.91.31.71.11.21.31.21.31.11.2-1.20.8
Change in fecal boli incidents, locomotor task0.30.30.4-0.4-0.5-0.6-0.5-0.6-0.4-0.30.5-0.6
Time >=10cm from walls, locomotor time 10.20.20.50.10.10.10.20.40.40.7-0.60.7
Bouts of movement, locomotor time 10.50.61.8-0.50.10.0-0.00.61.30.8-0.81.3
Total resting periods, locomotor time 10.50.61.6-0.30.20.20.20.61.30.9-0.91.2
Rest time, locomotor task time 10.60.81.30.91.11.00.90.91.10.7-0.70.3
Distance moved, locomotor task time 11.52.34.1-1.0-1.1-1.1-1.0-1.5-1.9-2.02.0-1.5
Vertical activity count, locomotor time 10.92.14.0-1.1-1.2-1.1-1.0-1.4-1.7-1.92.0-1.3
Time >=10cm from walls, locomotor time 20.10.20.50.30.50.40.60.40.70.4-0.40.1
Bouts of movement, locomotor time 20.10.20.8-0.9-0.5-0.4-0.3-0.10.10.4-0.40.5
Total resting periods, locomotor time 20.10.20.4-0.6-0.3-0.3-0.20.00.20.5-0.60.5
Rest time, locomotor task time 20.20.30.8-0.1-0.2-0.2-0.10.20.50.9-0.90.6
Distance moved, locomotor task time 20.91.13.50.10.30.1-0.1-0.5-1.0-1.91.8-1.3
Vertical activity count, locomotor time 20.70.92.00.80.90.81.0-0.0-0.6-1.21.3-1.4
Light reinforcement 10.71.73.50.70.70.60.51.31.61.7-1.71.9
Light reinforcement 20.00.10.20.30.40.40.40.30.00.1-0.10.1
Bone: marrow area0.30.81.00.70.70.80.91.01.00.8-0.91.0
Bone: maximum diameter0.20.31.1-0.0-0.10.00.00.41.10.6-0.61.0
Bone: maximum force1.32.24.50.80.80.80.81.52.11.8-1.82.0
Bone: maximum moment1.32.34.70.60.60.60.61.42.21.9-1.92.2
Mean time between licks in bursts0.92.33.61.11.11.21.31.71.71.7-1.71.9
Mean num. licks in bursts1.82.83.51.61.61.51.41.91.81.7-1.71.7
Cd content in liver2.42.75.02.02.02.12.21.70.71.3-1.30.3
Co content in liver0.20.30.60.60.50.60.60.0-0.4-0.40.4-0.8
Cu content in liver0.20.30.40.60.60.50.40.60.20.6-0.60.3
Fe content in liver0.20.30.50.50.50.50.50.50.20.7-0.70.3
K content in liver0.90.91.9-1.0-1.1-1.0-1.0-0.10.80.7-0.71.4
Mg content in liver1.11.13.4-0.8-0.8-0.9-0.90.21.11.1-1.11.8
Mn content in liver0.60.61.6-0.5-0.5-0.4-0.40.30.81.1-1.11.3
Na content in liver0.90.91.4-0.8-0.8-0.9-0.9-1.0-1.2-1.21.2-0.8
Rb content in liver0.50.61.3-0.9-0.9-1.1-1.1-0.5-0.30.4-0.40.4
Se content in liver0.60.71.01.01.00.90.90.90.60.8-0.80.5
Sr content in liver0.60.61.6-0.1-0.10.00.1-0.6-1.1-1.01.0-1.3
Zn content in liver0.20.20.30.30.30.30.40.50.30.6-0.60.5
Bone: minimum diameter1.83.37.10.90.90.91.01.82.62.1-2.12.7
Time in familiar zone, hab. session 10.40.41.00.40.50.30.1-0.2-0.4-0.90.9-1.0
Time in novel zone, hab. session 11.31.32.9-1.6-1.7-1.6-1.4-1.0-0.7-0.00.00.2
Total zone transitions, hab. session 10.60.81.6-0.7-0.8-0.7-0.7-0.9-0.7-1.21.2-0.8
Total locomotion distance, hab. session 12.02.94.1-2.0-2.0-2.0-1.9-1.8-1.4-1.51.5-0.8
Locomotion velocity, hab. session 11.72.43.6-1.8-1.9-1.8-1.8-1.7-1.2-1.41.4-0.7
Time in familiar zone, hab. session 20.10.10.40.30.20.10.10.30.60.2-0.20.4
Time in novel zone, hab. session 20.90.91.6-1.3-1.2-1.2-1.1-1.0-0.9-0.30.3-0.3
Total zone transitions, hab. session 20.10.10.30.20.10.20.3-0.1-0.4-0.50.5-0.6
Total locomotion distance, hab. session 20.20.20.4-0.3-0.4-0.4-0.4-0.5-0.5-0.60.6-0.5
Locomotion velocity, hab. session 20.10.10.3-0.1-0.2-0.2-0.1-0.3-0.4-0.50.5-0.5
Novel to familiar place preference ratio5.86.410.0-3.2-3.0-3.1-3.1-2.7-1.8-1.91.9-1.1
Novelty place preference7.47.912.3-3.5-3.4-3.5-3.5-3.0-2.1-2.02.0-1.2
Time in novel zone, NPP test8.18.613.5-3.7-3.6-3.7-3.7-3.2-2.1-2.12.1-1.2
Total zone transitions, NPP test0.71.02.21.51.31.41.30.6-0.1-0.50.5-0.7
Total locomotion distance, NPP test0.30.30.70.80.70.70.70.2-0.2-0.50.5-0.6
Locomotion velocity, NPP test0.40.51.21.10.91.01.00.50.2-0.20.2-0.3
Intraocular pressure0.71.01.71.31.01.00.91.10.91.0-1.00.8
Delta distance traveled before/after self-admin0.70.71.11.11.01.01.00.90.40.8-0.80.3
Delta ambulatory time before/after self-admin0.20.20.50.70.60.60.50.50.10.5-0.50.0
Parametrial fat weight0.20.50.90.91.01.00.90.70.50.1-0.10.1
Pavlov. Cond. lever latency0.81.12.2-1.5-1.4-1.5-1.4-0.9-0.40.1-0.10.4
Pavlov. Cond. magazine entry latency0.30.41.10.10.10.1-0.0-0.3-0.4-1.11.1-0.8
Pavlov. Cond. change in total contacts0.50.50.70.70.70.80.70.1-0.3-0.80.8-0.8
Pavlov. Cond. index score0.81.01.90.90.80.80.7-0.1-0.6-1.41.4-1.4
Pavlov. Cond. latency score0.70.91.51.21.21.21.10.4-0.1-0.90.9-0.9
Pavlov. Cond. lever contacts0.91.12.21.51.41.51.40.90.5-0.10.1-0.2
Pavlov. Cond. magazine entry number1.31.64.00.10.20.20.31.01.42.0-2.01.9
Pavlov. Cond. intertrial magazine entries0.50.61.00.30.40.50.70.71.01.0-1.00.9
Pavlov. Cond. lever-magazine prob. diff.0.70.91.90.70.70.60.5-0.2-0.6-1.41.4-1.3
Pavlov. Cond. response bias0.91.13.00.20.10.1-0.0-0.7-1.0-1.71.7-1.6
Pavlov. Cond. lever latency0.20.20.40.50.50.30.00.50.40.6-0.60.6
Pavlov. Cond. magazine entry latency0.30.31.0-0.2-0.2-0.00.1-0.5-0.5-0.80.8-1.0
Pavlov. Cond. change in total contacts0.30.51.50.90.81.11.20.60.30.0-0.1-0.2
Pavlov. Cond. index score0.30.31.0-0.1-0.10.10.3-0.4-0.6-0.90.9-1.0
Pavlov. Cond. latency score0.30.41.10.0-0.00.20.4-0.4-0.5-0.90.9-1.0
Pavlov. Cond. lever contacts0.20.30.4-0.6-0.7-0.4-0.2-0.6-0.5-0.60.6-0.6
Pavlov. Cond. magazine entry number0.60.81.70.40.50.40.20.90.81.3-1.31.3
Pavlov. Cond. intertrial magazine entries0.10.10.30.20.20.20.10.30.40.3-0.40.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.1-0.0-0.10.20.4-0.4-0.6-0.90.9-1.1
Pavlov. Cond. response bias0.10.20.3-0.4-0.5-0.2-0.0-0.5-0.4-0.50.5-0.5
Time in closed arm before self-admin0.20.20.6-0.7-0.8-0.7-0.6-0.5-0.3-0.00.00.1
Time in closed arm after self-admin0.30.30.7-0.6-0.8-0.8-0.8-0.30.20.0-0.00.6
Time in open arm before self-admin0.60.71.3-0.5-0.4-0.7-1.0-0.8-0.7-1.11.1-0.7
Time in open arm after self-admin0.10.10.4-0.2-0.0-0.1-0.1-0.3-0.5-0.50.5-0.6
Bone: periosteal estimation0.71.53.50.60.50.60.61.21.81.4-1.41.9
Bone: periosteal perimeter0.71.22.70.50.40.50.61.11.71.3-1.31.7
Bone: post-yield work0.91.32.31.51.51.51.51.10.80.6-0.6-0.1
Progressive ratio test 1 active lever presses1.62.03.81.81.91.71.61.50.91.1-1.00.5
Progressive ratio test 1 breakpoint1.82.24.01.92.01.81.71.60.91.2-1.10.5
Progressive ratio test 1 inactive lever presses0.81.22.31.41.51.41.31.10.30.9-0.90.2
Progressive ratio test 2 active lever presses1.11.23.90.91.00.80.6-0.3-1.5-1.01.0-2.0
Progressive ratio test 2 breakpoint1.11.24.00.80.90.60.5-0.4-1.6-1.11.1-2.0
Progressive ratio test 2 inactive lever presses0.20.40.90.50.60.50.5-0.1-0.8-0.40.4-1.0
Incentive Sensitization - Responses0.60.92.80.50.50.30.2-0.5-1.3-1.11.1-1.7
Incentive Sensitization - Breakpoint0.81.03.20.40.50.30.1-0.6-1.4-1.21.2-1.8
Sum of active levers in priming session hrs 5-62.01.82.41.51.51.51.41.41.01.4-1.40.7
Progressive ratio0.10.10.3-0.4-0.3-0.5-0.2-0.3-0.1-0.20.20.0
Food seeking constrained by brief footshock0.20.30.8-0.6-0.6-0.9-0.9-0.40.1-0.10.10.4
Seeking ratio, punishment vs. effort0.30.50.9-0.7-0.7-0.7-0.9-0.7-0.7-0.50.5-0.4
Retroperitoneal fat weight0.00.20.50.50.70.50.20.20.1-0.50.5-0.2
Reaction time number correct1.12.24.92.22.22.11.81.30.20.5-0.4-0.5
Reaction time mean minus median0.00.10.10.30.30.20.20.00.2-0.30.3-0.4
Reaction time mean minus median AUC0.10.30.8-0.2-0.2-0.3-0.3-0.5-0.3-0.80.7-0.9
Reaction time num false alarms0.00.00.00.0-0.1-0.1-0.2-0.00.1-0.00.00.1
Reaction time num false alarms AUC0.00.00.10.30.10.20.10.10.0-0.00.0-0.0
Reaction time trials correct on left1.12.24.92.22.22.11.81.30.20.5-0.4-0.5
Reaction time trials on left1.22.35.12.22.32.11.81.40.30.5-0.5-0.4
Reaction time mean1.42.23.01.61.71.71.71.61.41.3-1.30.8
Reaction time mean AUC1.11.82.31.41.51.51.51.41.31.2-1.20.7
Median of all reaction times1.62.33.11.61.61.71.71.61.41.5-1.50.9
Reaction time omissions2.02.94.71.31.31.31.21.92.21.9-1.92.1
Reaction time false alarm rate0.50.61.4-1.0-1.2-1.1-1.0-0.8-0.3-0.40.40.0
Reaction time premature initiation rate0.40.51.1-1.0-1.0-1.0-0.9-0.7-0.3-0.20.20.0
Reaction time premature initiations0.00.00.10.30.30.30.20.1-0.20.1-0.1-0.2
Std. dev. reaction times0.10.20.40.60.60.50.60.30.4-0.00.0-0.2
Reaction time trials completed1.22.35.12.22.32.11.81.40.30.5-0.5-0.4
Reaction time trials AUC1.22.24.82.22.22.11.81.40.30.6-0.6-0.3
Run reversals in cocaine runway, females0.30.31.3-0.5-0.5-0.2-0.3-0.6-1.1-0.30.3-0.8
Run reversals in cocaine runway, males0.20.20.40.50.60.60.70.2-0.3-0.30.3-0.5
Latency to leave start box in cocaine runway0.10.10.20.40.30.40.30.30.40.2-0.20.2
Latency to leave start box in cocaine runway, F0.00.00.10.10.20.20.10.20.10.0-0.00.1
Latency to leave start box in cocaine runway, M0.10.10.20.40.20.30.30.40.50.3-0.40.4
Std. dev. time between licks in bursts0.50.61.30.50.50.81.00.91.10.6-0.60.9
Total sessions with >9 infusions3.13.85.42.32.32.22.02.11.41.9-1.81.2
Short access day 1 total inactive lever presses1.31.73.1-1.1-1.1-1.2-1.2-1.5-1.8-1.31.2-1.3
Short access day 10 total inactive lever presses1.43.34.8-2.2-2.2-2.1-2.1-2.0-1.4-1.61.6-0.9
Short access day 1 total infusions0.70.91.51.21.21.21.21.00.30.7-0.70.2
Short access day 10 total infusions2.22.84.72.22.22.12.01.81.01.3-1.30.5
Short access total infusions2.43.15.32.32.32.22.11.90.91.3-1.30.6
Short access day 1 locomotion0.10.10.30.30.30.20.1-0.0-0.5-0.00.0-0.4
Short access day 10 total locomotion0.00.00.0-0.0-0.00.00.00.10.10.2-0.20.2
Short access total locomotion1.01.22.01.41.41.31.21.20.51.1-1.10.4
One hour access (0.3 mA shock)0.40.41.20.60.60.60.5-0.1-0.7-0.60.7-1.1
Compulsive drug intake0.30.40.70.50.40.70.80.70.60.7-0.70.6
One hour access (shock baseline)0.30.51.30.70.90.70.6-0.0-0.8-0.50.6-1.2
Social response proportion3.03.44.71.71.71.82.02.01.72.2-2.21.5
Social responses0.00.00.1-0.2-0.3-0.20.1-0.2-0.10.2-0.2-0.1
Social time3.75.16.32.22.11.81.72.52.52.5-2.52.3
Soleus weight7.321.435.3-5.8-5.8-5.9-5.9-4.9-2.6-3.33.3-1.5
Bone: stiffness0.60.92.40.40.40.50.40.91.51.1-1.11.3
Tibialis anterior weight0.41.22.3-0.8-0.7-0.7-0.8-1.2-1.2-1.51.5-1.3
Time to tail flick, vehicle, before self-admin2.02.12.71.41.51.51.51.61.61.4-1.41.2
Time to tail flick, vehicle, after self-admin0.91.22.31.51.41.41.51.00.50.8-0.8-0.1
Time to tail flick, test, before self-admin1.11.22.2-1.4-1.5-1.4-1.4-1.1-0.8-0.30.3-0.1
Time to tail flick, test, after self-admin2.93.04.7-2.0-2.1-2.1-2.2-2.0-1.3-1.31.3-0.9
Delta time to tail flick, vehicle, before/after SA0.20.20.60.80.60.60.70.30.10.1-0.1-0.3
Delta time to tail flick, test, before/after SA1.51.52.0-1.1-1.1-1.2-1.2-1.4-1.1-1.41.4-1.2
Tibia length2.97.910.23.13.03.13.03.22.82.4-2.42.2
Ambulatory time before self-admin0.50.81.0-0.9-1.0-0.9-0.8-1.0-0.7-0.90.9-0.6
Ambulatory time after self-admin0.00.00.1-0.1-0.3-0.10.0-0.2-0.20.0-0.0-0.2
Bone: tissue strength3.53.59.70.30.30.30.31.62.72.4-2.53.1
Total heroin consumption4.04.77.2-2.3-2.4-2.6-2.7-2.4-2.0-1.71.7-1.3
Bone: trabecular number6.210.312.9-3.4-3.5-3.4-3.4-3.6-3.2-2.92.9-2.5
Bone: trabecular spacing4.76.38.12.52.42.52.42.82.82.5-2.52.2
Bone: trabecular thickness0.20.30.6-0.8-0.8-0.8-0.7-0.6-0.2-0.10.10.0
Bone: trabecular tissue density0.71.01.70.90.91.01.01.11.30.8-0.81.0
Water consumed over 24 hours0.00.00.10.20.20.20.20.20.40.1-0.10.1
Number of responses in last shaping day0.40.51.3-0.2-0.2-0.3-0.3-0.7-1.1-0.70.8-1.1