Hub : Genes

Zfp958l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Zfp958l1 0.16 0.08 0.0e+00 0.09 0.14 0.13 0.14 1.8e-13 5.8e-20 2.6e-19 5.2e-20
2 pVTA gene expression Zfp958l1 0.18 0.09 4.1e-15 0.1 0.18 0.19 0.14 1.2e-08 1.7e-14 6.1e-15 5.2e-11
3 PL gene expression Zfp958l1 0.07 0.04 1.4e-07 0.05 0.06 0.05 0.06 2.4e-06 7.6e-07 6.4e-06 9.5e-07
4 IC gene expression Zfp958l1 0.1 0.07 1.6e-03 0.06 0.06 0.07 0.06 1.8e-03 1.1e-03 9.7e-04 1.3e-03
5 IC mRNA stability Zfp958l1 0.27 0.15 6.9e-05 0.05 0.1 0.19 0.07 2.9e-03 3.7e-05 2.2e-08 5.2e-04
6 Eye mRNA stability Zfp958l1 0.36 0.18 2.7e-03 0.11 0.04 -0 0.06 8.3e-03 8.4e-02 3.5e-01 5.2e-02
7 Liver mRNA stability Zfp958l1 0.27 0.12 0.0e+00 0.19 0.2 0.2 0.2 2.0e-20 2.2e-22 7.5e-22 4.8e-22
8 BLA gene expression Zfp958l1 0.1 0.08 4.9e-04 0.04 0.04 0.06 0.06 1.9e-03 2.8e-03 5.1e-04 4.2e-04
9 LHb mRNA stability Zfp958l1 0.55 0.22 2.2e-06 0.18 0.23 0.19 0.21 4.8e-05 4.0e-06 2.6e-05 1.2e-05
10 Adipose mRNA stability Zfp958l1 0.77 0.08 0.0e+00 0.46 0.5 0.5 0.5 4.0e-57 1.1e-63 1.3e-63 1.3e-63
11 Adipose gene expression Zfp958l1 0.15 0.09 2.1e-11 0.03 0.06 0.07 0.07 7.2e-04 9.4e-08 3.3e-08 5.5e-08
12 OFC mRNA stability Zfp958l1 0.37 0.18 1.3e-04 0.1 0.12 0.11 0.12 2.2e-03 8.0e-04 1.7e-03 6.9e-04
13 Liver gene expression Zfp958l1 0.74 0.09 0.0e+00 0.52 0.52 0.52 0.52 1.8e-67 6.3e-67 4.0e-68 4.0e-68
14 NAcc mRNA stability Zfp958l1 0.57 0.13 0.0e+00 0.3 0.32 0.33 0.33 8.0e-47 6.7e-50 2.3e-51 5.1e-51
15 Brain mRNA stability Zfp958l1 0.79 0.07 0.0e+00 0.6 0.63 0.64 0.64 5.5e-69 3.8e-76 1.3e-76 9.8e-77
16 PL mRNA stability Zfp958l1 0.67 0.15 0.0e+00 0.32 0.34 0.34 0.34 9.1e-36 1.4e-37 2.6e-38 8.0e-39
17 Liver intron excision ratio chr12_9453960_9456804 0.14 0.08 1.6e-10 0.05 0.06 0.05 0.05 5.7e-06 5.9e-07 2.8e-06 1.3e-06
18 Liver intron excision ratio chr12_9456481_9456804 0.06 0.04 5.6e-05 0.03 0.03 0.02 0.02 5.2e-04 5.3e-04 1.1e-03 8.9e-04
19 BLA mRNA stability Zfp958l1 0.24 0.12 9.1e-07 0.13 0.1 0.13 0.14 3.2e-07 3.6e-06 1.7e-07 1.2e-07
20 RMTg mRNA stability Zfp958l1 0.51 0.15 6.5e-06 0.2 0.16 0.15 0.2 5.2e-06 4.3e-05 7.4e-05 6.4e-06
21 IL mRNA stability Zfp958l1 0.53 0.14 5.2e-11 0.34 0.4 0.39 0.39 4.6e-09 1.2e-10 1.7e-10 1.7e-10
22 pVTA mRNA stability Zfp958l1 0.33 0.13 7.8e-12 0.14 0.12 0.13 0.1 2.0e-11 1.8e-09 2.1e-10 2.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density6.911.918.8-3.6-4.3-4.3-3.6-2.44.14.1-4.34.04.0-0.23.83.83.63.73.70.3-2.53.13.02.53.0
Area under the delay curve0.70.81.91.21.41.31.41.3-1.3-1.11.0-1.0-1.01.2-0.6-0.4-0.4-0.5-0.50.50.4-0.2-0.1-0.3-0.3
BMI with tail3.110.719.6-2.9-3.8-3.9-3.2-2.24.44.2-3.54.14.2-0.23.53.33.33.23.11.0-3.33.02.73.12.2
BMI without tail1.95.813.6-3.5-3.5-3.2-3.7-3.53.22.9-3.02.62.7-2.01.91.81.51.61.6-1.4-1.01.10.80.80.5
Body weight7.833.969.2-8.1-8.3-8.3-8.0-7.98.37.6-6.76.76.6-4.54.94.54.14.14.0-2.2-3.52.92.12.71.8
Weight adjusted by age0.40.61.6-1.2-1.1-1.0-1.2-0.90.80.8-0.90.70.7-0.80.70.70.60.60.6-0.6-0.00.50.30.10.1
Bone surface6.011.018.4-3.8-4.3-4.2-3.7-2.44.03.9-4.23.73.8-0.63.63.73.53.53.5-0.2-2.02.92.72.22.6
Bone volume6.611.816.8-2.9-4.0-3.9-3.2-1.63.83.9-4.13.93.90.63.94.03.93.93.91.0-2.73.53.52.93.4
Breakpoint value in progressive ratio session0.10.10.3-0.5-0.6-0.4-0.6-0.20.20.2-0.50.30.2-0.20.30.40.50.40.4-0.30.30.40.5-0.10.4
Number of licking bursts2.94.79.1-0.20.70.9-0.3-1.9-1.0-1.41.8-1.7-1.8-2.7-2.5-2.6-2.7-2.6-2.7-2.62.3-2.9-3.0-2.6-3.0
Context. condit. distance diff. score4.35.29.7-2.8-2.9-3.1-2.1-1.43.12.9-2.92.62.6-0.72.42.52.32.32.20.1-1.81.91.51.61.6
Locomotion velocity, session 10.40.51.10.80.90.80.90.9-0.5-0.61.0-0.7-0.60.2-0.8-0.7-0.6-0.7-0.80.10.2-0.6-0.6-0.3-0.5
Locomotion distance, session 10.50.62.41.31.31.21.11.5-1.0-1.00.8-0.9-0.61.0-0.5-0.3-0.3-0.4-0.30.70.1-0.1-0.10.10.0
Locomotion velocity, session 21.82.12.90.81.51.51.00.6-1.5-1.71.6-1.7-1.5-0.4-1.7-1.6-1.7-1.7-1.7-0.91.4-1.7-1.6-1.5-1.5
Locomotion distance, session 21.72.34.11.21.81.91.01.1-1.8-2.01.7-2.0-1.60.0-1.6-1.5-1.5-1.6-1.5-0.71.8-1.3-1.3-1.4-1.3
Locomotion velocity, session 30.91.01.9-0.8-0.8-0.9-0.70.30.90.8-1.20.81.00.31.21.31.41.21.30.5-0.71.31.20.91.3
Locomotion distance, session 30.70.71.5-0.7-0.4-0.6-0.40.80.50.5-1.20.50.80.11.21.21.21.11.20.4-0.41.11.10.71.1
Stereotopy head waving bouts, day 30.91.13.4-1.8-1.6-1.5-1.5-1.61.31.2-1.11.01.0-0.90.70.90.80.60.8-0.9-0.20.50.50.10.2
Stereotopy head waving duration, day 30.10.10.50.2-0.1-0.00.30.10.00.10.30.20.10.70.10.40.40.20.30.4-0.20.40.50.20.3
Locomotion velocity, session 70.60.72.40.91.21.01.51.2-1.0-0.90.8-0.9-1.00.8-0.7-0.6-0.6-0.6-0.60.60.1-0.6-0.4-0.3-0.3
Locomotion distance, session 70.20.20.80.30.50.40.90.8-0.5-0.50.2-0.5-0.60.3-0.3-0.4-0.3-0.3-0.40.20.1-0.3-0.3-0.3-0.2
Stereotopy head waving bouts, day 70.60.72.20.51.11.11.01.5-1.3-1.30.6-1.2-1.00.3-0.6-0.3-0.4-0.5-0.3-0.31.3-0.3-0.2-0.8-0.3
Stereotopy head waving duration, day 71.31.52.91.21.71.61.61.7-1.7-1.71.4-1.6-1.50.4-1.1-0.9-0.9-1.1-0.9-0.21.4-0.7-0.7-1.0-0.7
Locomotion velocity, session 80.10.10.2-0.20.20.10.20.0-0.2-0.20.3-0.3-0.3-0.3-0.3-0.2-0.3-0.3-0.3-0.40.4-0.3-0.3-0.4-0.4
Locomotion distance, session 80.81.12.6-1.6-1.4-1.5-1.1-0.61.61.3-1.41.11.3-0.61.11.10.90.90.9-0.3-0.70.80.50.60.5
Degree of sensitization distance2.22.33.51.61.61.71.70.6-1.7-1.61.9-1.5-1.80.4-1.8-1.8-1.8-1.6-1.8-0.21.0-1.6-1.5-1.2-1.4
Degree of sensitization stereotypy0.70.73.80.61.21.11.12.0-1.2-1.20.6-1.1-0.90.5-0.4-0.2-0.2-0.3-0.20.11.1-0.00.0-0.5-0.0
Conditioned locomotion2.73.14.7-0.6-1.5-1.5-1.6-0.71.71.8-1.82.02.01.02.02.12.01.92.21.3-1.92.12.02.02.1
Cocaine response after cond. corrected0.70.91.80.1-0.4-0.4-0.20.40.40.6-0.90.80.81.21.21.11.11.21.21.0-0.91.21.31.11.3
Cocaine response after cond. not corrected1.72.03.2-0.0-0.7-0.8-0.20.60.91.1-1.41.31.31.61.71.71.71.81.81.4-1.51.71.81.71.8
Cocaine response before conditioning0.81.01.6-0.5-0.7-0.9-0.30.31.11.0-1.21.01.10.61.21.31.21.11.10.8-1.11.10.91.11.0
Saline control response1.72.210.5-2.3-1.1-1.1-1.2-2.10.60.3-0.4-0.2-0.2-3.2-0.7-0.9-1.1-1.0-1.1-2.61.3-1.6-1.7-1.7-1.8
Bone: connectivity density6.810.520.0-4.3-4.4-4.5-3.6-2.74.34.0-4.23.73.7-1.33.33.33.13.13.0-0.7-1.82.42.21.82.1
Bone: cortical apparent density0.20.31.11.10.70.70.60.0-0.4-0.50.9-0.4-0.50.4-0.6-0.6-0.5-0.5-0.50.5-0.0-0.5-0.4-0.0-0.3
Bone: cortical area1.32.04.1-1.7-2.0-2.0-1.8-1.61.91.9-1.41.71.6-0.81.31.31.21.21.1-0.2-1.00.90.90.90.8
Bone: cortical porosity0.30.41.20.20.70.60.61.1-0.6-0.80.6-0.9-0.5-0.1-0.5-0.5-0.5-0.6-0.5-0.50.8-0.5-0.3-0.6-0.5
Bone: cortical porosity0.50.62.10.61.00.91.01.4-0.8-1.00.8-1.0-0.80.1-0.6-0.6-0.6-0.6-0.6-0.20.8-0.5-0.3-0.6-0.5
Bone: cortical thickness1.52.54.6-1.8-2.2-2.1-2.1-1.52.12.0-1.81.91.9-0.61.51.61.51.41.4-0.2-1.11.11.01.01.1
Bone: cortical thickness0.40.51.8-1.3-1.1-1.0-1.2-1.10.80.6-0.70.40.4-1.40.20.20.20.10.1-0.90.4-0.2-0.2-0.4-0.2
Bone: cortical tissue density0.20.31.21.10.70.80.60.0-0.5-0.50.9-0.4-0.50.4-0.6-0.6-0.6-0.5-0.50.40.0-0.5-0.5-0.1-0.3
Condit. Reinf. active minus inactive responses0.20.31.10.90.20.20.1-0.10.20.30.40.50.30.90.10.20.20.00.21.0-1.00.40.40.80.4
Condit. Reinf. active-inactive response ratio0.20.30.90.6-0.10.00.1-0.10.10.30.00.50.41.00.40.40.40.20.40.9-0.90.50.50.80.5
Condit. Reinf. active responses0.10.10.30.50.10.1-0.10.00.20.20.10.30.40.60.10.20.20.10.20.6-0.60.30.30.60.3
Condit. Reinf. inactive responses0.20.30.60.50.70.70.40.6-0.5-0.70.5-0.7-0.5-0.0-0.6-0.5-0.5-0.5-0.5-0.20.5-0.5-0.6-0.4-0.4
Incentive salience index mean0.40.51.80.7-0.1-0.2-0.10.00.60.6-0.00.80.80.90.50.60.60.50.61.2-1.30.80.81.20.8
Condit. Reinf. lever presses0.50.72.00.5-0.3-0.4-0.20.20.70.8-0.30.90.91.00.70.90.90.90.91.2-1.41.01.01.31.1
Condit. Reinf. active minus inactive responses1.11.43.6-0.80.10.2-0.1-0.8-0.4-0.70.5-1.0-1.0-1.9-1.2-1.3-1.4-1.3-1.3-1.71.4-1.6-1.6-1.6-1.6
Condit. Reinf. active-inactive response ratio1.71.93.40.10.80.90.60.0-1.1-1.31.1-1.5-1.6-1.4-1.6-1.8-1.7-1.5-1.6-1.31.7-1.9-1.7-1.7-1.6
Condit. Reinf. active responses0.40.52.4-1.4-0.6-0.6-0.8-0.90.40.1-0.4-0.2-0.0-1.6-0.2-0.3-0.5-0.4-0.4-1.30.8-0.7-0.8-0.8-0.7
Condit. Reinf. inactive responses0.70.92.0-1.4-1.1-1.2-1.0-0.81.21.1-1.21.01.1-0.41.01.00.80.80.9-0.2-0.60.70.50.60.5
Condit. Reinf. lever presses1.01.42.0-0.9-1.2-1.3-0.9-0.51.41.4-1.41.41.40.11.41.31.21.31.40.7-1.31.21.11.21.2
Condit. Reinf. lever reinforcers received0.40.51.9-1.0-0.2-0.2-0.4-0.70.0-0.2-0.1-0.5-0.3-1.4-0.5-0.6-0.7-0.6-0.6-1.20.9-0.9-1.0-0.9-0.9
Conditioned reinforcement - actives1.01.75.3-2.3-1.9-1.7-2.1-2.21.71.3-1.41.01.2-1.80.60.70.40.40.5-1.40.30.1-0.3-0.2-0.2
Conditioned reinforcement - inactives0.30.41.4-0.80.10.0-0.6-0.3-0.1-0.5-0.1-0.7-0.3-1.1-0.4-0.3-0.4-0.5-0.4-1.11.2-0.6-0.6-0.9-0.6
Conditioned locomotion0.91.14.2-2.1-1.6-1.3-1.8-1.31.00.8-1.50.60.8-1.20.70.90.60.60.8-1.40.70.30.1-0.30.2
Patch foraging indifference point 0 sec1.73.14.8-1.0-1.5-1.8-1.3-0.82.02.1-1.62.12.20.61.91.82.01.91.81.2-2.21.91.92.01.7
Patch foraging indifference point AUC0.60.92.3-1.5-1.4-1.3-1.4-1.41.51.1-1.00.91.0-1.20.50.60.20.20.4-0.8-0.40.0-0.30.1-0.1
Delay disc. indifference point, 0s delay0.20.30.70.50.80.50.80.6-0.5-0.50.6-0.6-0.70.2-0.5-0.5-0.5-0.5-0.50.20.1-0.4-0.4-0.3-0.4
Delay disc. indifference point, 16s delay0.20.21.10.30.70.50.81.1-0.4-0.40.2-0.4-0.20.80.10.20.10.0-0.00.40.00.20.20.1-0.1
Delay disc. indifference point, 2s delay1.31.55.11.91.81.61.82.2-1.4-1.21.0-0.8-0.82.3-0.2-0.10.10.0-0.11.5-0.20.40.70.40.6
Delay disc. indifference point, 24s delay1.31.53.11.11.61.61.61.5-1.8-1.71.2-1.6-1.50.7-1.1-0.9-1.0-1.0-1.0-0.01.1-0.9-0.7-0.9-0.8
Delay disc. indifference point, 4s delay0.60.72.51.00.90.60.91.3-0.5-0.30.3-0.1-0.01.60.40.50.50.50.51.4-0.90.90.90.80.8
Delay disc. indifference point, 8s delay0.20.20.70.60.50.70.70.6-0.8-0.60.6-0.4-0.60.6-0.4-0.3-0.3-0.3-0.30.10.4-0.1-0.1-0.3-0.2
Indifference point function ln k0.30.61.20.00.50.40.0-0.9-0.5-0.50.8-0.5-0.7-0.8-0.9-1.1-0.8-0.8-1.0-0.70.8-0.9-0.8-0.8-1.0
Indifference point function log k0.30.61.20.00.50.40.0-0.9-0.5-0.50.8-0.5-0.7-0.8-0.9-1.1-0.8-0.8-1.0-0.70.8-0.9-0.8-0.8-1.0
Patch foraging total patch changes 0 sec1.93.65.6-1.1-1.6-2.0-1.5-1.02.22.3-1.82.32.40.52.11.92.12.01.91.2-2.32.02.02.21.9
Patch foraging total patch changes 12 sec3.64.78.8-1.4-2.0-2.4-1.8-1.23.02.7-2.22.62.80.22.32.12.22.12.11.3-2.82.11.92.41.8
Patch foraging total patch changes 18 sec1.42.13.5-1.0-1.3-1.6-1.2-0.31.81.7-1.51.71.90.41.71.71.61.51.60.7-1.61.61.41.61.5
Patch foraging total patch changes 24 sec1.32.23.8-1.0-1.5-1.7-1.3-1.12.01.9-1.51.91.90.21.51.51.51.41.50.8-1.91.51.11.61.4
Patch foraging total patch changes 6 sec1.82.75.0-1.3-1.8-2.0-1.7-1.22.22.1-1.62.02.10.21.61.61.61.51.60.6-1.91.51.31.61.4
Patch foraging time to switch 0 sec0.81.66.52.11.61.31.82.6-1.1-0.90.9-0.5-0.52.30.10.20.50.40.42.0-0.60.81.10.91.0
Patch foraging water rate 0 sec1.43.09.6-3.0-2.5-2.4-2.5-3.12.21.9-1.81.51.5-2.60.80.60.40.50.5-1.9-0.1-0.0-0.3-0.2-0.3
Patch foraging water rate 12 sec0.20.52.1-0.8-0.6-0.2-0.9-1.3-0.3-0.2-0.3-0.2-0.3-1.1-0.2-0.2-0.4-0.2-0.2-1.41.2-0.6-0.6-1.0-0.3
Patch foraging water rate 18 sec0.81.32.70.30.70.80.6-0.6-0.8-0.81.2-0.9-1.0-1.0-1.3-1.5-1.5-1.4-1.5-1.01.0-1.4-1.4-1.2-1.6
Patch foraging water rate 24 sec1.01.45.6-1.8-1.5-1.1-1.9-2.40.80.7-0.90.40.4-2.1-0.1-0.2-0.5-0.2-0.2-2.10.9-0.8-1.0-1.0-0.7
Patch foraging water rate 6 sec0.50.81.7-1.2-1.3-1.1-1.3-0.71.01.0-1.30.90.9-0.50.90.80.80.90.9-0.5-0.10.60.60.30.6
Seeking ratio, delayed vs. immediate footshock0.60.82.41.31.31.11.51.5-1.0-0.81.1-0.7-0.70.9-0.7-0.7-0.5-0.6-0.70.7-0.1-0.4-0.20.0-0.4
Distance traveled before self-admin0.40.51.91.20.90.81.11.4-0.5-0.50.8-0.4-0.21.3-0.3-0.2-0.1-0.3-0.30.9-0.40.00.10.40.1
Distance traveled after self-admin0.10.10.3-0.2-0.2-0.10.20.20.10.2-0.30.20.30.50.30.40.30.20.30.1-0.20.30.30.20.2
Extensor digitorum longus weight2.911.327.5-5.2-4.8-4.8-4.5-3.74.44.1-4.33.63.7-2.93.12.82.72.52.5-1.8-1.31.81.51.21.3
Bone: elastic displacement0.30.31.3-0.50.20.3-0.10.6-0.4-0.6-0.2-0.8-0.3-0.6-0.4-0.4-0.4-0.3-0.3-1.11.1-0.5-0.4-0.9-0.4
Bone: elastic work1.92.57.7-2.8-2.3-2.2-2.7-2.01.91.6-2.21.31.5-2.01.11.00.91.01.0-1.70.00.40.2-0.10.3
Bone: endosteal estimation0.40.83.0-1.7-1.1-1.0-1.4-1.70.50.5-0.70.30.2-1.70.10.00.00.00.0-1.50.8-0.2-0.3-0.7-0.5
Bone: endosteal perimeter0.71.43.4-1.8-1.8-1.8-1.7-1.81.51.6-1.11.41.1-1.20.90.80.90.80.7-0.6-0.50.60.60.30.2
Epididymis fat weight0.93.04.5-0.8-1.7-1.6-1.6-0.91.92.0-1.62.12.10.92.02.01.91.91.91.0-2.01.91.61.91.6
Delta time in closed arm before/after self-admin1.00.92.5-0.30.20.20.5-0.2-0.2-0.40.7-0.7-0.7-0.9-1.1-1.0-1.3-1.3-1.3-1.10.9-1.4-1.6-1.1-1.4
Delta time in open arm before/after self-admin1.71.76.51.81.51.21.32.5-1.3-0.90.3-0.5-0.31.70.60.51.01.00.82.0-0.61.31.81.01.4
Diff in mean of infusions in LGA sessions0.20.20.7-0.7-0.6-0.5-0.8-0.30.40.3-0.70.30.4-0.30.50.50.50.40.5-0.30.20.40.40.00.3
Delay discount exponential model param1.01.12.5-1.4-1.6-1.5-1.6-1.61.61.3-1.11.21.1-1.40.70.50.50.50.6-0.6-0.50.20.10.30.3
Extinction: sum of active levers before priming1.31.53.50.0-0.7-0.7-0.5-0.10.61.0-1.01.21.10.91.51.41.61.61.51.0-1.21.71.91.31.7
Active lever presses in extinction session 61.41.42.2-0.9-1.5-1.2-1.4-1.01.11.2-1.51.31.40.31.21.51.31.31.40.1-0.71.21.10.81.3
Bone: final force0.81.35.2-1.9-1.6-1.5-1.6-2.31.31.2-0.60.80.6-2.20.1-0.0-0.0-0.1-0.2-1.40.1-0.5-0.7-0.5-0.7
Bone: final moment0.71.14.7-1.7-1.4-1.4-1.5-2.21.11.0-0.40.70.5-2.1-0.0-0.1-0.1-0.2-0.3-1.40.1-0.5-0.7-0.5-0.7
Food consumed during 24 hour testing period0.50.72.0-0.40.20.10.1-0.2-0.1-0.40.5-0.6-0.6-1.4-0.9-1.1-0.9-1.0-1.1-1.00.9-1.1-1.1-0.9-1.2
Glucose0.61.03.41.91.31.61.00.8-1.4-1.31.3-1.0-1.01.4-0.9-0.6-0.8-0.8-0.50.80.2-0.4-0.4-0.1-0.2
Heart weight0.50.82.3-0.9-0.4-0.3-0.3-1.40.2-0.00.1-0.3-0.4-1.5-0.7-0.8-1.0-0.8-0.8-1.40.8-1.2-1.4-1.0-1.3
Delay discount hyperbolic model param0.80.92.2-1.3-1.5-1.3-1.5-1.51.41.2-1.01.00.9-1.40.60.40.30.40.4-0.7-0.30.1-0.00.20.1
Intermittent access intake day 1-15 change0.20.42.1-1.5-1.0-0.8-0.6-0.50.70.6-1.00.40.5-0.40.30.50.20.20.4-0.60.00.0-0.3-0.1-0.0
Intermittent access intake escalation0.10.31.9-1.4-0.9-0.8-0.5-0.40.70.5-0.80.30.4-0.40.20.40.10.10.4-0.50.0-0.0-0.3-0.1-0.1
Intermittent access intake escalation 20.00.00.1-0.2-0.10.10.20.0-0.1-0.0-0.1-0.0-0.10.3-0.00.1-0.0-0.10.20.2-0.2-0.0-0.10.10.1
Intermitt. access day 1 inactive lever presses0.10.31.0-0.6-0.00.0-0.3-0.1-0.1-0.4-0.2-0.5-0.4-0.8-0.4-0.4-0.3-0.4-0.4-0.91.0-0.6-0.5-0.8-0.5
Intermitt. access day 15 inactive lever presses0.20.51.90.50.30.10.71.40.10.1-0.10.20.41.10.40.40.50.50.51.1-0.80.60.80.90.9
Intermitt. access escalation Index0.20.30.40.30.30.40.60.4-0.4-0.50.6-0.5-0.6-0.3-0.6-0.7-0.7-0.6-0.6-0.30.3-0.7-0.6-0.5-0.5
Intermittent access day 1 total infusions0.30.41.00.61.00.90.60.8-0.8-0.90.7-0.9-0.8-0.0-0.6-0.6-0.5-0.5-0.6-0.10.8-0.5-0.3-0.5-0.4
Intermittent access day 15 total infusions0.10.10.6-0.50.20.20.20.6-0.2-0.4-0.2-0.6-0.3-0.2-0.2-0.1-0.2-0.2-0.1-0.50.8-0.3-0.3-0.5-0.2
Intermittent access terminal intake (last 3 days)0.10.10.4-0.10.40.40.30.6-0.3-0.50.0-0.6-0.30.0-0.2-0.1-0.2-0.2-0.1-0.10.5-0.2-0.2-0.3-0.0
Intermittent access total infusions0.10.20.60.20.70.60.30.8-0.5-0.70.2-0.7-0.40.1-0.2-0.1-0.1-0.1-0.1-0.10.6-0.1-0.1-0.30.1
Intermittent access day 1 locomotion0.20.31.30.71.00.90.61.1-0.8-0.80.4-0.7-0.50.5-0.2-0.2-0.1-0.0-0.10.30.60.10.3-0.10.3
Intermittent access day 15 total locomotion0.20.42.3-0.60.30.4-0.20.2-0.8-0.9-0.1-1.0-0.7-0.5-0.4-0.1-0.4-0.3-0.1-1.01.5-0.4-0.4-1.1-0.3
Intermittent access total locomotion0.10.20.50.20.70.60.30.7-0.6-0.70.2-0.7-0.50.1-0.1-0.1-0.1-0.10.00.10.60.10.1-0.20.2
Intermittent access standard deviation0.20.31.0-0.5-0.3-0.2-0.70.2-0.00.1-0.90.10.40.60.60.90.80.71.00.2-0.00.70.70.30.9
Left kidney weight5.726.358.2-7.6-7.4-7.4-6.7-6.27.36.6-6.45.75.8-4.64.53.93.63.73.6-2.5-2.52.51.72.01.5
Right kidney weight3.616.640.1-6.3-5.8-5.9-5.9-6.35.75.1-4.74.24.3-4.62.92.52.22.22.1-2.9-1.41.30.60.90.3
Cocaine induced anxiety0.40.51.10.3-0.4-0.5-0.4-0.40.70.7-0.40.80.80.90.70.80.70.70.81.0-1.00.80.81.00.9
Post-drug Anxiety1.41.56.02.41.51.31.71.6-1.0-0.61.2-0.3-0.52.2-0.2-0.20.00.00.12.3-1.20.60.71.10.9
Baseline Anxiety3.23.78.02.72.82.62.72.3-2.6-2.32.6-2.0-2.21.0-1.8-2.0-1.5-1.6-1.70.90.6-1.1-0.8-0.8-0.8
Tail length2.911.243.8-5.8-4.7-4.3-5.5-6.63.63.1-3.42.32.2-5.21.00.80.30.60.5-4.30.9-0.6-1.3-1.3-1.1
Length with tail6.427.779.2-8.9-7.6-7.6-8.0-8.67.06.1-6.14.84.9-6.83.32.82.32.42.3-4.8-0.80.8-0.10.1-0.0
Length without tail6.320.443.7-6.5-6.2-6.6-5.7-5.26.65.9-5.35.15.3-3.44.13.73.53.43.3-1.5-2.92.41.82.31.8
Times rat made contact with spout2.02.35.6-0.50.10.4-0.7-1.6-0.8-0.90.9-1.1-1.1-2.4-1.5-1.7-1.7-1.7-1.7-2.21.9-1.9-1.9-2.0-2.0
Lifetime Intake0.10.20.70.50.70.60.30.9-0.5-0.60.3-0.6-0.40.4-0.2-0.1-0.0-0.0-0.00.30.30.10.1-0.00.3
Liver weight, left2.74.510.2-3.2-3.0-3.1-2.9-2.93.12.8-2.42.42.3-2.01.81.51.41.31.3-1.1-1.00.90.50.70.5
Liver weight, right2.23.98.2-2.4-2.5-2.7-2.6-2.92.92.6-2.22.42.4-1.41.81.51.51.41.4-0.5-1.41.31.01.10.5
Locomotor activity0.91.45.5-1.8-0.9-0.8-1.2-1.80.80.30.1-0.10.0-2.3-0.6-0.8-1.0-1.0-0.9-2.11.2-1.2-1.4-1.3-1.3
Locomotor testing distance0.30.62.2-1.4-0.8-0.8-1.1-1.30.90.5-0.20.20.4-1.5-0.1-0.3-0.4-0.3-0.3-1.30.5-0.5-0.7-0.6-0.5
Locomotor testing rearing0.10.10.6-0.2-0.1-0.1-0.30.30.00.1-0.40.00.20.40.50.30.30.60.60.2-0.00.40.40.20.8
Locomotion in novel chamber1.62.06.9-1.1-0.20.2-0.9-1.6-0.5-0.80.2-1.1-0.9-1.9-1.3-1.1-1.5-1.4-1.2-2.62.3-1.6-1.8-2.1-1.7
Locomotion in novel chamber post-restriction1.42.48.6-1.3-0.7-0.0-1.3-1.8-0.5-0.70.1-0.9-0.9-2.4-1.3-1.2-1.5-1.3-1.2-2.92.4-1.7-1.9-2.3-1.5
Fecal boli incidents, locomotor time 10.50.72.7-1.6-0.8-1.0-1.1-1.50.90.5-0.70.10.3-1.4-0.00.0-0.3-0.3-0.1-1.20.4-0.6-0.8-0.5-0.6
Change in fecal boli incidents, locomotor task0.30.30.60.80.60.70.40.3-0.6-0.60.8-0.5-0.6-0.0-0.6-0.6-0.6-0.5-0.5-0.00.3-0.4-0.3-0.3-0.4
Time >=10cm from walls, locomotor time 10.70.73.31.20.60.61.71.8-0.5-0.20.60.1-0.21.60.10.10.20.20.11.4-0.80.60.60.70.5
Bouts of movement, locomotor time 10.80.93.2-1.5-1.3-1.1-1.7-1.81.00.8-1.00.70.7-1.30.40.40.20.30.2-1.30.4-0.1-0.2-0.4-0.4
Total resting periods, locomotor time 10.80.82.7-1.5-1.3-1.2-1.5-1.71.10.9-1.10.80.8-1.20.50.50.30.30.2-1.20.20.0-0.2-0.2-0.4
Rest time, locomotor task time 11.11.32.7-1.7-1.4-1.6-1.6-1.21.61.3-1.61.11.4-0.91.11.21.01.00.9-0.7-0.40.70.60.40.3
Distance moved, locomotor task time 10.71.02.11.11.01.21.20.6-1.2-1.11.4-1.0-1.20.3-1.1-1.1-1.1-1.1-1.10.00.6-0.9-0.9-0.7-0.9
Vertical activity count, locomotor time 10.20.40.8-0.1-0.00.30.0-0.4-0.4-0.50.6-0.5-0.6-0.3-0.7-0.5-0.8-0.8-0.7-0.90.8-0.7-0.8-0.9-0.8
Time >=10cm from walls, locomotor time 20.81.22.1-0.4-0.7-0.90.00.61.21.1-1.01.11.30.91.31.41.21.21.31.0-1.41.41.31.31.1
Bouts of movement, locomotor time 21.21.94.6-1.7-1.7-1.6-1.8-0.81.31.4-2.11.41.5-0.41.61.61.51.61.6-0.3-0.41.31.30.71.0
Total resting periods, locomotor time 21.42.45.2-1.7-1.8-1.8-1.9-0.81.61.6-2.31.61.7-0.31.81.81.71.81.7-0.1-0.61.51.50.91.2
Rest time, locomotor task time 20.50.61.70.0-0.3-0.6-0.3-0.20.90.9-0.61.00.90.20.80.60.90.90.60.9-1.30.80.91.10.7
Distance moved, locomotor task time 21.31.53.30.00.50.90.50.1-1.1-1.21.1-1.2-1.3-0.7-1.3-1.2-1.4-1.5-1.4-1.51.8-1.4-1.5-1.7-1.5
Vertical activity count, locomotor time 20.81.25.4-1.6-0.9-0.5-0.9-1.10.1-0.2-0.3-0.4-0.4-1.4-0.6-0.2-0.8-0.8-0.6-2.31.8-1.0-1.2-1.6-1.2
Light reinforcement 10.51.26.31.61.71.32.22.5-1.1-1.11.0-1.0-0.91.2-0.5-0.6-0.3-0.4-0.51.10.1-0.10.20.10.0
Light reinforcement 20.40.61.30.80.90.81.10.7-0.6-0.71.1-0.7-0.90.2-0.9-0.8-0.9-1.0-1.00.20.5-0.7-0.8-0.4-0.8
Bone: marrow area0.40.83.0-1.7-1.1-1.0-1.4-1.70.50.5-0.60.30.2-1.70.1-0.0-0.00.0-0.0-1.50.8-0.3-0.3-0.7-0.5
Bone: maximum diameter1.01.94.1-1.8-2.0-2.0-1.9-2.01.71.8-1.31.61.4-1.01.11.11.11.01.1-0.4-0.80.90.80.60.6
Bone: maximum force0.91.64.6-2.1-1.9-2.0-1.7-1.91.81.7-1.21.41.2-1.90.80.60.60.60.5-0.9-0.60.20.00.2-0.0
Bone: maximum moment0.81.44.0-2.0-1.7-1.8-1.6-1.91.71.6-1.01.31.1-1.80.70.50.50.50.4-0.9-0.50.2-0.00.2-0.1
Mean time between licks in bursts0.51.22.81.71.51.61.31.1-1.4-1.41.4-1.2-1.20.9-1.0-0.9-0.9-1.0-0.80.40.6-0.5-0.5-0.5-0.5
Mean num. licks in bursts0.71.12.4-0.3-0.6-0.6-0.20.80.50.7-1.10.80.90.81.31.31.41.31.40.8-0.81.41.51.01.4
Cd content in liver2.12.34.10.51.11.30.4-0.3-1.3-1.51.6-1.6-1.4-0.9-1.8-1.8-1.9-1.9-1.9-1.51.5-1.9-2.0-1.7-1.9
Co content in liver0.91.02.0-0.10.60.50.1-0.6-0.5-0.80.9-0.9-0.9-1.1-1.1-1.2-1.2-1.3-1.4-1.21.1-1.3-1.3-1.3-1.4
Cu content in liver0.10.10.7-0.0-0.2-0.0-0.7-0.90.00.10.00.10.1-0.0-0.0-0.0-0.1-0.10.0-0.2-0.1-0.00.0-0.00.0
Fe content in liver3.13.86.5-1.4-2.3-2.3-1.9-1.82.32.5-2.02.52.2-0.02.02.01.91.91.90.9-2.31.81.61.91.5
K content in liver0.30.31.10.30.1-0.00.41.10.20.1-0.20.20.30.80.50.50.50.40.60.7-0.60.60.80.60.8
Mg content in liver0.20.20.4-0.20.20.10.40.30.1-0.20.4-0.4-0.3-0.5-0.4-0.5-0.5-0.6-0.5-0.40.1-0.6-0.5-0.4-0.6
Mn content in liver0.91.02.10.60.91.11.31.1-1.5-1.30.7-1.3-1.5-0.1-1.0-1.0-1.0-0.9-0.8-0.30.9-1.0-0.8-1.0-0.6
Na content in liver0.30.31.0-0.9-0.9-1.0-0.4-0.30.90.9-0.60.70.5-0.30.40.50.40.30.4-0.1-0.40.10.30.30.3
Rb content in liver1.21.45.02.11.41.31.62.0-1.0-0.70.8-0.3-0.32.20.20.20.50.50.52.0-0.80.91.21.01.1
Se content in liver4.45.28.7-0.8-2.0-2.1-1.2-0.32.52.5-2.12.62.51.32.62.62.62.62.61.9-2.92.62.52.72.5
Sr content in liver0.30.30.7-0.3-0.2-0.0-0.4-0.8-0.1-0.10.4-0.1-0.2-0.7-0.5-0.6-0.6-0.7-0.6-0.90.5-0.7-0.7-0.6-0.6
Zn content in liver1.82.06.8-2.2-2.1-1.8-2.6-2.41.71.5-1.61.31.4-1.51.00.80.60.70.7-1.4-0.30.30.2-0.00.1
Bone: minimum diameter0.20.41.20.40.70.60.70.2-0.5-0.61.1-0.6-0.7-0.3-0.8-0.9-0.8-0.9-0.9-0.10.4-0.7-0.5-0.5-0.8
Time in familiar zone, hab. session 10.10.10.40.50.40.30.50.5-0.2-0.10.1-0.0-0.10.40.10.10.10.10.10.6-0.40.20.10.30.2
Time in novel zone, hab. session 10.10.10.6-0.5-0.5-0.3-0.8-0.80.10.1-0.10.10.2-0.40.10.10.00.10.1-0.70.50.00.1-0.3-0.0
Total zone transitions, hab. session 11.01.42.91.21.71.61.31.3-1.6-1.61.4-1.5-1.30.3-1.0-1.1-1.0-1.1-1.00.11.0-0.7-0.6-0.8-0.7
Total locomotion distance, hab. session 10.50.73.20.80.80.51.01.8-0.3-0.3-0.0-0.20.11.20.60.50.60.50.71.3-0.61.01.00.81.0
Locomotion velocity, hab. session 10.81.17.11.41.41.11.82.7-0.9-0.90.4-0.7-0.51.50.20.10.20.20.31.5-0.30.60.70.60.8
Time in familiar zone, hab. session 20.10.10.60.40.00.10.10.3-0.3-0.0-0.20.1-0.10.80.40.40.40.50.50.5-0.20.50.60.30.6
Time in novel zone, hab. session 20.20.20.50.30.50.40.50.1-0.1-0.30.7-0.4-0.3-0.3-0.7-0.7-0.6-0.7-0.7-0.10.2-0.5-0.6-0.2-0.6
Total zone transitions, hab. session 21.21.62.7-0.10.90.80.20.0-0.9-1.21.0-1.4-1.1-1.4-1.3-1.3-1.5-1.5-1.5-1.41.6-1.5-1.7-1.5-1.6
Total locomotion distance, hab. session 20.40.51.80.41.10.90.91.3-0.7-1.00.5-1.1-0.7-0.1-0.5-0.6-0.6-0.6-0.5-0.10.8-0.4-0.5-0.5-0.4
Locomotion velocity, hab. session 20.40.61.90.41.10.90.81.4-0.9-1.10.4-1.2-0.8-0.2-0.6-0.6-0.6-0.7-0.5-0.20.9-0.5-0.6-0.6-0.4
Novel to familiar place preference ratio1.51.72.40.61.31.31.00.5-1.3-1.41.4-1.5-1.4-0.7-1.5-1.6-1.5-1.5-1.5-0.81.3-1.4-1.3-1.3-1.4
Novelty place preference1.92.02.91.01.61.51.30.8-1.5-1.61.7-1.7-1.5-0.5-1.7-1.7-1.6-1.7-1.6-0.61.4-1.5-1.3-1.3-1.5
Time in novel zone, NPP test1.51.62.50.71.31.31.00.4-1.2-1.41.5-1.4-1.3-0.5-1.5-1.5-1.5-1.6-1.5-0.71.2-1.4-1.3-1.2-1.4
Total zone transitions, NPP test0.20.30.6-0.30.40.2-0.2-0.2-0.2-0.40.4-0.6-0.3-0.6-0.4-0.3-0.5-0.6-0.6-0.70.8-0.5-0.7-0.6-0.7
Total locomotion distance, NPP test0.30.42.3-0.20.3-0.00.41.50.2-0.0-0.6-0.10.40.50.70.70.70.70.70.6-0.20.80.80.50.8
Locomotion velocity, NPP test0.20.22.0-0.40.30.10.21.4-0.1-0.3-0.5-0.30.10.10.50.50.50.40.50.00.40.60.50.10.5
Intraocular pressure1.82.65.3-2.2-2.0-2.1-2.3-1.41.81.7-2.31.51.7-0.81.71.71.51.61.7-0.4-0.61.31.20.81.2
Delta distance traveled before/after self-admin0.20.21.1-1.1-0.6-0.6-0.5-0.80.40.4-0.70.20.2-0.90.20.2-0.00.10.2-0.70.2-0.0-0.2-0.3-0.2
Delta ambulatory time before/after self-admin0.00.00.1-0.20.00.10.2-0.2-0.1-0.00.0-0.1-0.1-0.1-0.1-0.1-0.3-0.2-0.1-0.1-0.0-0.1-0.2-0.1-0.2
Parametrial fat weight0.41.01.9-0.2-0.8-0.8-0.10.21.21.2-0.71.31.10.71.10.91.11.11.01.0-1.41.11.21.30.9
Pavlov. Cond. lever latency0.60.72.6-1.6-1.1-1.0-1.1-1.60.70.6-0.70.40.3-1.50.2-0.1-0.2-0.1-0.1-1.30.4-0.4-0.6-0.6-0.6
Pavlov. Cond. magazine entry latency0.20.20.8-0.3-0.4-0.1-0.8-0.70.1-0.0-0.1-0.10.1-0.8-0.3-0.4-0.4-0.3-0.3-0.90.4-0.5-0.5-0.5-0.4
Pavlov. Cond. change in total contacts0.30.31.10.90.40.30.30.60.00.00.20.20.31.00.20.30.30.30.31.1-0.70.50.60.80.5
Pavlov. Cond. index score0.00.10.20.50.00.1-0.20.00.00.1-0.10.10.20.40.00.10.20.20.20.3-0.30.20.20.30.3
Pavlov. Cond. latency score0.10.10.50.70.30.3-0.00.3-0.1-0.10.20.00.10.5-0.00.10.20.10.20.4-0.20.30.30.30.3
Pavlov. Cond. lever contacts0.50.62.41.51.01.01.01.5-0.6-0.60.6-0.4-0.21.4-0.20.00.10.10.11.2-0.40.40.50.60.5
Pavlov. Cond. magazine entry number0.10.10.50.20.30.10.70.7-0.00.00.10.1-0.10.60.20.30.20.20.20.7-0.40.30.30.40.3
Pavlov. Cond. intertrial magazine entries0.20.20.90.70.60.60.90.6-0.5-0.40.5-0.3-0.50.6-0.5-0.4-0.4-0.4-0.40.4-0.1-0.4-0.4-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.50.10.1-0.20.0-0.00.1-0.10.20.20.40.10.20.20.20.20.4-0.40.20.20.40.3
Pavlov. Cond. response bias0.00.00.3-0.0-0.2-0.1-0.5-0.40.10.1-0.10.10.2-0.3-0.1-0.1-0.00.0-0.0-0.30.0-0.1-0.1-0.1-0.0
Pavlov. Cond. lever latency0.10.20.5-0.10.20.2-0.1-0.4-0.0-0.20.3-0.3-0.2-0.4-0.4-0.4-0.4-0.5-0.6-0.60.4-0.5-0.5-0.5-0.7
Pavlov. Cond. magazine entry latency1.31.54.62.11.71.81.81.8-1.7-1.51.5-1.2-1.31.2-0.9-0.9-0.7-0.6-0.70.90.3-0.5-0.3-0.2-0.1
Pavlov. Cond. change in total contacts0.10.10.20.40.30.30.30.0-0.3-0.30.4-0.3-0.5-0.2-0.4-0.5-0.5-0.4-0.4-0.00.2-0.5-0.5-0.3-0.3
Pavlov. Cond. index score0.20.31.31.20.70.80.80.8-0.8-0.60.7-0.4-0.60.7-0.3-0.3-0.3-0.1-0.10.7-0.1-0.1-0.10.10.2
Pavlov. Cond. latency score0.30.31.41.20.80.80.90.8-0.7-0.50.8-0.4-0.50.7-0.3-0.4-0.3-0.1-0.20.8-0.2-0.1-0.00.20.2
Pavlov. Cond. lever contacts0.20.30.80.2-0.1-0.10.20.70.00.2-0.40.30.30.60.60.50.50.70.70.8-0.60.60.60.60.9
Pavlov. Cond. magazine entry number1.21.53.4-1.8-1.7-1.7-1.6-1.51.71.5-1.61.31.5-0.81.11.21.00.90.9-0.5-0.60.80.60.60.5
Pavlov. Cond. intertrial magazine entries0.40.62.4-1.5-0.8-0.9-1.0-1.40.70.5-0.70.30.4-1.60.0-0.1-0.2-0.2-0.2-1.30.4-0.5-0.5-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.61.20.91.01.00.9-1.0-0.80.9-0.6-0.80.6-0.6-0.6-0.5-0.3-0.40.60.1-0.3-0.3-0.1-0.0
Pavlov. Cond. response bias0.20.31.40.90.40.50.71.2-0.5-0.30.1-0.1-0.20.90.20.20.30.40.40.9-0.30.40.50.50.8
Time in closed arm before self-admin0.91.13.8-1.2-0.6-0.3-1.2-1.70.1-0.2-0.1-0.5-0.2-1.6-0.8-0.7-0.9-0.8-0.7-1.91.4-1.1-1.3-1.3-1.2
Time in closed arm after self-admin2.93.17.3-1.2-0.30.1-0.7-1.8-0.3-0.70.6-1.1-1.1-2.3-1.8-1.6-2.1-2.0-1.9-2.72.1-2.4-2.6-2.3-2.5
Time in open arm before self-admin0.10.10.40.1-0.0-0.10.1-0.40.10.10.30.0-0.2-0.3-0.4-0.4-0.5-0.5-0.5-0.30.1-0.5-0.6-0.3-0.5
Time in open arm after self-admin1.11.23.41.20.80.70.81.9-0.7-0.3-0.10.00.11.60.90.81.21.21.01.7-0.61.51.81.11.5
Bone: periosteal estimation0.71.54.5-2.1-1.9-1.7-1.9-2.01.31.3-1.21.11.0-1.70.70.60.60.60.6-1.20.10.20.2-0.10.0
Bone: periosteal perimeter1.01.73.2-1.4-1.8-1.8-1.4-1.21.71.8-1.21.71.5-0.51.31.21.31.21.10.1-1.21.01.21.00.8
Bone: post-yield work2.13.04.7-1.3-1.7-1.8-1.1-0.21.91.9-2.01.92.00.32.21.92.02.12.10.9-1.72.01.91.81.9
Progressive ratio test 1 active lever presses0.40.51.9-1.2-0.8-0.6-1.4-1.10.60.3-0.70.10.3-1.30.20.2-0.00.10.1-1.31.0-0.1-0.2-0.6-0.2
Progressive ratio test 1 breakpoint0.40.51.8-1.1-0.8-0.6-1.3-1.10.60.2-0.80.10.3-1.30.20.2-0.00.10.2-1.21.0-0.1-0.2-0.6-0.2
Progressive ratio test 1 inactive lever presses0.30.41.7-1.2-0.4-0.3-0.8-0.30.4-0.1-0.5-0.30.0-1.3-0.1-0.2-0.2-0.2-0.2-1.31.3-0.5-0.5-0.8-0.6
Progressive ratio test 2 active lever presses0.60.73.0-1.3-0.6-0.5-1.2-1.00.3-0.1-0.6-0.3-0.1-1.5-0.2-0.1-0.3-0.2-0.2-1.71.4-0.5-0.6-1.1-0.6
Progressive ratio test 2 breakpoint0.60.72.8-1.2-0.5-0.4-1.1-0.90.2-0.2-0.5-0.4-0.1-1.5-0.3-0.2-0.3-0.3-0.2-1.71.4-0.6-0.7-1.1-0.6
Progressive ratio test 2 inactive lever presses0.91.46.0-2.4-1.4-1.2-2.0-1.71.10.6-1.50.20.6-2.00.20.30.00.20.3-2.01.3-0.3-0.5-0.9-0.5
Incentive Sensitization - Responses0.00.10.4-0.00.40.30.20.6-0.4-0.40.0-0.4-0.30.1-0.10.00.10.00.0-0.20.40.10.1-0.30.1
Incentive Sensitization - Breakpoint0.10.10.30.00.40.30.20.6-0.4-0.40.1-0.4-0.30.1-0.10.00.10.00.0-0.20.40.10.1-0.30.1
Sum of active levers in priming session hrs 5-62.72.54.7-0.4-1.1-1.1-0.90.01.11.4-1.51.61.61.11.91.92.02.02.01.3-1.52.12.21.82.0
Progressive ratio0.81.22.51.31.51.31.50.8-0.9-1.01.6-1.1-1.00.1-1.2-1.4-1.1-1.3-1.30.20.2-1.1-1.1-0.5-1.0
Food seeking constrained by brief footshock0.40.51.80.3-0.3-0.0-0.30.2-0.10.3-0.50.50.61.30.70.90.80.80.90.7-0.70.91.00.81.0
Seeking ratio, punishment vs. effort0.81.23.0-1.4-1.6-1.2-1.7-1.00.70.9-1.60.91.0-0.11.21.41.01.21.3-0.60.11.01.00.20.9
Retroperitoneal fat weight1.25.310.20.3-1.4-1.3-0.40.51.92.2-1.62.62.52.42.52.42.62.72.52.7-3.22.82.83.12.6
Reaction time number correct0.30.61.9-1.3-1.1-0.9-1.3-1.20.60.5-0.70.30.3-1.30.10.1-0.10.00.1-1.40.7-0.4-0.4-0.7-0.1
Reaction time mean minus median0.20.51.60.10.90.70.40.9-1.1-1.00.2-1.1-0.9-0.4-0.5-0.4-0.4-0.4-0.4-0.61.3-0.4-0.3-0.9-0.5
Reaction time mean minus median AUC0.51.32.90.61.61.31.01.4-1.6-1.60.9-1.7-1.5-0.3-1.0-0.9-0.9-0.9-0.9-0.61.6-0.8-0.7-1.3-0.8
Reaction time num false alarms0.91.22.90.71.10.70.6-0.4-0.2-0.71.7-0.8-0.8-0.8-1.3-1.5-1.4-1.7-1.7-0.50.6-1.3-1.4-0.7-1.6
Reaction time num false alarms AUC0.20.31.00.20.40.00.1-0.80.50.10.9-0.1-0.0-0.7-0.6-0.7-0.7-1.0-1.0-0.20.0-0.6-0.7-0.1-0.9
Reaction time trials correct on left0.30.61.9-1.3-1.1-0.9-1.3-1.20.60.5-0.70.30.3-1.30.10.1-0.10.00.1-1.40.7-0.4-0.4-0.7-0.1
Reaction time trials on left0.30.62.0-1.2-1.1-0.8-1.2-1.10.50.4-0.60.20.2-1.3-0.00.0-0.2-0.0-0.0-1.40.8-0.5-0.5-0.7-0.1
Reaction time mean2.84.510.02.73.22.92.92.7-2.9-2.72.4-2.6-2.51.1-1.8-1.8-1.7-1.7-1.60.71.2-1.2-0.9-1.1-1.1
Reaction time mean AUC2.64.19.12.63.02.82.82.6-2.8-2.62.3-2.5-2.41.2-1.7-1.7-1.6-1.6-1.50.81.1-1.1-0.9-1.0-1.1
Median of all reaction times3.75.311.53.23.43.23.33.0-3.0-2.92.7-2.6-2.61.6-1.9-2.0-1.8-1.8-1.71.20.9-1.2-1.0-0.9-1.1
Reaction time omissions0.60.92.51.21.41.31.41.6-1.3-1.20.9-1.2-1.00.4-0.6-0.6-0.5-0.6-0.70.30.7-0.4-0.2-0.5-0.6
Reaction time false alarm rate0.20.31.30.80.90.40.6-0.20.2-0.21.1-0.2-0.2-0.0-0.6-0.7-0.6-0.9-0.90.4-0.3-0.4-0.50.1-0.8
Reaction time premature initiation rate0.50.72.20.50.80.81.41.5-0.7-0.90.6-1.0-0.9-0.1-0.7-0.9-0.8-0.7-0.80.00.7-0.9-0.8-0.6-0.9
Reaction time premature initiations0.20.40.9-0.10.20.30.70.8-0.3-0.50.2-0.7-0.6-0.5-0.6-0.8-0.7-0.5-0.6-0.50.8-0.9-0.8-0.7-0.7
Std. dev. reaction times0.91.63.81.22.01.71.41.7-1.8-1.81.2-1.8-1.50.2-1.0-1.0-0.9-1.0-0.9-0.11.3-0.7-0.5-1.0-0.7
Reaction time trials completed0.30.62.0-1.2-1.1-0.8-1.2-1.10.50.4-0.60.20.2-1.3-0.00.0-0.2-0.0-0.0-1.40.8-0.5-0.5-0.7-0.1
Reaction time trials AUC0.20.41.5-1.1-1.0-0.8-1.1-1.00.50.4-0.70.30.3-1.10.10.1-0.10.10.1-1.20.7-0.3-0.3-0.60.1
Run reversals in cocaine runway, females0.60.62.40.70.70.60.51.6-0.7-0.5-0.3-0.2-0.11.50.50.60.70.70.81.2-0.50.80.90.61.2
Run reversals in cocaine runway, males0.40.51.7-0.0-0.1-0.00.4-0.80.10.00.6-0.1-0.4-0.6-0.8-0.9-0.9-0.7-1.1-0.60.3-1.0-1.0-0.6-1.3
Latency to leave start box in cocaine runway0.20.31.10.70.40.41.10.5-0.2-0.10.9-0.0-0.30.5-0.4-0.6-0.5-0.5-0.60.7-0.5-0.4-0.40.2-0.4
Latency to leave start box in cocaine runway, F0.10.10.70.1-0.1-0.20.5-0.30.30.40.40.40.10.3-0.0-0.1-0.3-0.3-0.30.5-0.8-0.3-0.30.4-0.3
Latency to leave start box in cocaine runway, M0.20.20.40.70.30.50.60.6-0.5-0.30.6-0.2-0.40.2-0.3-0.5-0.3-0.4-0.50.10.2-0.2-0.1-0.2-0.3
Std. dev. time between licks in bursts0.50.71.7-0.20.30.10.4-0.5-0.1-0.30.7-0.6-0.6-1.1-1.0-1.0-1.1-1.2-1.1-0.90.7-1.2-1.3-0.9-1.3
Total sessions with >9 infusions0.20.20.90.60.50.30.50.90.1-0.00.20.00.10.60.20.10.20.20.10.9-0.50.30.30.60.4
Short access day 1 total inactive lever presses0.10.20.5-0.4-0.6-0.6-0.7-0.50.70.5-0.60.40.5-0.20.40.40.30.40.4-0.10.00.30.20.20.3
Short access day 10 total inactive lever presses0.71.83.7-1.7-1.5-1.6-1.9-1.01.51.3-1.91.11.5-0.31.51.61.41.41.6-0.1-0.61.31.10.81.2
Short access day 1 total infusions0.40.52.01.00.50.40.51.2-0.2-0.00.20.20.21.20.40.40.60.60.51.4-0.80.80.91.01.0
Short access day 10 total infusions0.91.12.20.30.0-0.20.21.20.50.5-0.80.70.91.31.11.21.31.31.21.5-1.21.41.41.41.5
Short access total infusions0.40.51.91.10.60.50.51.2-0.2-0.10.10.10.11.20.40.40.60.60.51.4-0.70.80.90.91.0
Short access day 1 locomotion0.81.02.20.91.31.31.21.5-1.4-1.30.9-1.2-1.10.3-0.9-0.9-0.8-0.7-0.9-0.00.9-0.7-0.6-0.7-0.6
Short access day 10 total locomotion0.00.10.3-0.10.3-0.00.10.60.20.0-0.2-0.00.30.20.30.30.30.20.30.3-0.10.30.30.30.2
Short access total locomotion0.40.42.01.11.11.00.81.4-0.8-0.80.5-0.6-0.40.9-0.1-0.1-0.00.0-0.00.70.30.20.40.10.4
One hour access (0.3 mA shock)1.21.45.2-1.5-0.00.2-0.7-0.3-0.6-1.0-0.3-1.3-0.9-1.8-0.8-0.6-0.9-0.8-0.7-2.22.3-1.2-1.3-1.9-1.2
Compulsive drug intake0.70.83.11.11.21.40.80.6-1.8-1.31.1-1.1-1.20.8-0.8-0.7-0.6-0.7-0.60.20.5-0.4-0.2-0.6-0.3
One hour access (shock baseline)0.50.72.8-1.4-0.6-0.6-0.8-0.60.60.0-0.5-0.30.1-1.7-0.3-0.3-0.5-0.4-0.4-1.71.2-0.8-1.0-1.0-0.9
Social response proportion2.12.38.7-2.1-0.8-0.5-1.1-1.90.0-0.2-0.3-0.7-0.6-3.0-1.0-0.9-1.3-1.2-1.2-2.82.0-1.5-1.8-2.0-2.0
Social responses0.81.04.8-2.2-0.9-1.0-0.8-0.70.70.4-1.2-0.00.2-2.20.10.2-0.2-0.1-0.1-1.81.1-0.4-0.6-0.9-1.0
Social time3.64.98.32.32.92.72.61.9-2.5-2.62.7-2.5-2.60.2-2.4-2.4-2.3-2.2-2.5-0.01.6-2.0-1.8-1.6-1.9
Soleus weight1.95.610.0-3.1-3.0-3.1-2.3-1.43.12.9-3.22.72.8-1.22.52.42.42.42.1-0.3-1.52.01.91.51.3
Bone: stiffness0.20.31.1-0.8-0.7-0.9-0.5-1.00.90.80.00.60.4-1.00.1-0.0-0.1-0.1-0.2-0.2-0.5-0.2-0.30.1-0.4
Tibialis anterior weight3.210.728.2-5.3-4.7-4.7-4.5-3.84.34.0-4.13.53.5-3.22.92.62.42.32.2-2.0-1.21.71.20.91.0
Time to tail flick, vehicle, before self-admin0.20.31.31.10.60.50.60.2-0.3-0.20.8-0.1-0.21.1-0.3-0.1-0.1-0.2-0.20.7-0.60.00.00.30.1
Time to tail flick, vehicle, after self-admin0.20.30.60.30.1-0.10.4-0.70.30.20.70.1-0.3-0.6-0.6-0.7-0.6-0.7-0.70.2-0.4-0.7-0.70.0-0.7
Time to tail flick, test, before self-admin0.70.72.3-1.3-1.0-1.0-0.4-1.51.20.8-0.30.50.4-1.2-0.3-0.3-0.6-0.5-0.5-0.90.0-0.7-1.0-0.3-1.1
Time to tail flick, test, after self-admin0.20.21.10.70.40.20.60.70.20.20.30.30.20.80.10.10.20.00.11.1-1.00.20.20.80.4
Delta time to tail flick, vehicle, before/after SA0.10.00.20.0-0.0-0.20.30.00.30.20.10.1-0.1-0.5-0.1-0.3-0.2-0.2-0.20.3-0.2-0.2-0.20.2-0.2
Delta time to tail flick, test, before/after SA0.60.62.21.30.90.90.61.5-0.8-0.50.4-0.3-0.11.40.30.30.50.40.41.2-0.50.60.80.71.0
Tibia length1.54.216.2-3.6-2.7-2.5-3.5-4.02.01.8-1.71.21.2-3.40.50.30.10.10.0-2.80.7-0.4-0.7-1.0-1.0
Ambulatory time before self-admin0.20.31.10.50.20.10.41.00.10.1-0.00.20.41.00.40.40.60.40.40.8-0.60.60.60.70.6
Ambulatory time after self-admin0.30.30.7-0.0-0.3-0.30.20.40.40.4-0.40.50.70.90.50.70.60.50.60.6-0.80.70.60.70.6
Bone: tissue strength0.40.41.3-0.4-0.5-0.7-0.4-0.31.00.9-0.50.80.9-0.10.50.40.50.50.40.4-1.10.50.40.80.4
Total heroin consumption0.80.94.51.41.31.21.32.1-1.2-0.90.6-0.6-0.41.40.00.10.40.30.31.2-0.30.60.90.50.9
Bone: trabecular number4.57.413.3-3.1-3.7-3.5-3.3-2.53.33.4-3.53.23.1-0.52.82.82.62.72.7-0.1-1.82.11.91.82.0
Bone: trabecular spacing2.12.86.72.62.52.32.62.0-1.9-1.82.3-1.6-1.71.1-1.5-1.5-1.3-1.4-1.41.20.1-0.9-0.8-0.3-0.7
Bone: trabecular thickness6.68.313.8-3.0-3.7-3.5-3.2-1.93.33.3-3.73.33.3-0.13.23.23.03.13.20.1-1.92.72.62.02.6
Bone: trabecular tissue density0.50.71.80.61.00.71.30.9-0.6-0.71.0-0.9-0.9-0.2-0.9-0.9-1.0-0.9-1.00.10.4-0.9-1.1-0.5-0.8
Water consumed over 24 hours2.22.910.4-1.5-0.4-0.4-0.8-2.00.1-0.30.5-0.8-0.8-3.2-1.5-1.8-1.8-1.8-1.9-2.61.8-2.2-2.3-2.1-2.4
Number of responses in last shaping day0.10.10.50.50.30.10.50.70.20.00.10.00.20.0-0.0-0.20.10.10.00.4-0.20.10.20.30.3