Zfp873

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Zfp873 0.15 0.11 2.2e-03 0.07 0.06 0.02 0.05 1.1e-02 1.7e-02 1.0e-01 2.5e-02
2 BLA mRNA stability Zfp873 0.12 0.08 7.5e-07 0.1 0.12 0.12 0.13 3.7e-06 4.9e-07 4.8e-07 3.0e-07
3 NAcc gene expression Zfp873 0.03 0.02 9.2e-04 0.03 0.02 0.02 0.03 2.3e-04 4.2e-03 6.8e-04 4.9e-04
4 PL alternative TSS XM_039080424.1 0.02 0.02 1.6e-03 0.03 0.02 0.02 0.03 4.0e-04 1.2e-03 9.2e-04 7.8e-04
5 pVTA gene expression Zfp873 0.09 0.06 8.8e-04 0.05 0.07 0.06 0.06 2.8e-03 6.7e-04 1.3e-03 1.2e-03
6 Liver mRNA stability Zfp873 0.05 0.04 5.0e-06 0.03 0.04 0.03 0.03 2.2e-04 6.8e-05 1.6e-04 1.5e-04
7 OFC gene expression Zfp873 0.11 0.08 5.9e-03 0.08 0.1 0.09 0.09 5.4e-03 2.8e-03 4.4e-03 4.2e-03
8 BLA gene expression Zfp873 0.17 0.1 5.6e-10 0.16 0.2 0.2 0.2 5.6e-09 9.5e-11 9.5e-11 1.1e-10
9 PL gene expression Zfp873 0.11 0.07 1.1e-12 0.11 0.12 0.12 0.12 4.4e-12 5.8e-13 3.6e-13 5.4e-13
10 PL mRNA stability Zfp873 0.02 0.02 6.1e-03 0.01 0.01 0.02 0.01 7.1e-03 1.3e-02 5.0e-03 2.6e-02
11 pVTA alternative TSS XM_039080424.1 0.07 0.05 2.6e-03 0.04 0.06 0.06 0.06 5.0e-03 1.2e-03 2.1e-03 1.7e-03
12 Brain gene expression Zfp873 0.17 0.1 6.1e-14 0.13 0.13 0.13 0.13 2.9e-12 7.1e-12 5.5e-12 5.6e-12
13 Brain intron excision ratio chr7_7930031_7951682 0.03 0.03 6.9e-03 0.02 0.01 0.01 0.01 7.8e-03 1.4e-02 4.8e-02 2.2e-02
14 BLA alternative TSS XM_039080424.1 0.05 0.04 5.0e-03 0.04 0.04 0.05 0.04 2.0e-03 3.0e-03 1.8e-03 2.4e-03
15 Adipose gene expression Zfp873 0.06 0.04 4.3e-05 0.04 0.02 0.02 0.03 4.3e-05 1.3e-03 1.5e-03 8.1e-04
16 Brain mRNA stability Zfp873 0.08 0.06 6.7e-06 0.05 0.05 0.05 0.05 3.3e-05 2.2e-05 1.5e-05 3.7e-05
17 NAcc mRNA stability Zfp873 0.04 0.03 7.8e-04 0.02 0.03 0.02 0.02 6.9e-04 2.0e-04 1.1e-03 1.6e-03
18 Liver gene expression Zfp873 0.04 0.03 1.9e-03 0.02 0.02 0.02 0.02 2.2e-03 2.1e-03 5.3e-03 2.1e-03
19 Liver isoform ratio NM_001421390.1 0.03 0.03 5.9e-03 0.01 0 0.01 0 1.9e-02 1.9e-01 5.7e-02 9.6e-02
20 Liver intron excision ratio chr7_7930031_7951682 0.11 0.07 1.1e-08 0.06 0.06 0.05 0.05 2.3e-07 6.0e-07 1.3e-06 2.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.32.27.71.2-1.21.2-1.2-0.50.5-0.40.40.01.70.0-0.61.6-1.3-0.52.2-1.92.82.62.6
Area under the delay curve1.51.52.6-1.11.2-1.21.21.4-1.41.4-1.4-1.5-1.0-1.5-1.6-1.21.2-1.5-0.8-1.50.60.50.4
BMI with tail5.317.123.2-4.64.6-4.64.64.7-4.74.7-4.8-4.8-4.3-4.7-4.6-4.34.4-4.6-3.6-3.1-0.2-1.1-0.8
BMI without tail2.24.66.3-2.52.5-2.42.42.3-2.42.3-2.3-2.4-2.5-2.2-2.0-2.42.3-2.1-2.2-1.0-0.8-1.6-1.0
Body weight1.04.35.7-2.42.3-2.32.32.4-2.42.4-2.4-2.3-2.2-2.4-2.2-2.32.3-2.2-2.0-1.4-0.3-0.6-0.6
Weight adjusted by age0.50.51.9-0.90.8-0.70.70.7-0.70.7-0.6-0.8-0.8-0.5-0.3-0.80.5-0.5-0.80.1-0.7-1.4-0.8
Bone surface3.15.416.22.3-2.22.2-2.2-1.31.3-1.11.00.62.80.6-0.32.5-2.2-0.23.4-2.44.03.93.9
Bone volume3.25.416.22.3-2.22.2-2.2-1.31.3-1.11.00.62.80.6-0.32.6-2.2-0.23.4-2.44.03.93.9
Breakpoint value in progressive ratio session3.64.07.11.9-2.02.0-2.0-2.32.3-2.32.32.51.52.42.72.0-1.72.51.42.2-0.8-0.6-0.4
Number of licking bursts0.50.61.9-0.80.8-0.80.80.5-0.50.5-0.4-0.2-0.9-0.30.0-0.30.7-0.0-0.70.8-1.4-1.4-1.4
Context. condit. distance diff. score0.30.40.9-0.70.7-0.60.60.7-0.70.7-0.7-0.6-0.6-0.7-0.6-0.90.6-0.7-0.8-0.4-0.2-0.2-0.2
Locomotion velocity, session 11.11.22.21.3-1.31.3-1.3-1.11.1-1.01.00.81.50.90.60.5-1.40.60.9-0.31.31.41.4
Locomotion distance, session 10.81.03.41.0-1.00.9-0.9-0.60.6-0.60.50.31.30.3-0.10.2-1.1-0.00.9-1.11.81.81.8
Locomotion velocity, session 24.35.17.92.7-2.72.6-2.6-2.42.4-2.32.32.12.82.01.62.1-2.71.72.40.11.92.12.1
Locomotion distance, session 22.33.25.62.1-2.12.0-2.0-1.81.8-1.71.61.42.41.40.91.3-2.21.01.8-0.42.02.12.1
Locomotion velocity, session 34.85.67.82.5-2.52.6-2.6-2.72.7-2.72.82.82.32.82.82.4-2.52.82.02.0-0.20.20.2
Locomotion distance, session 30.00.00.10.0-0.00.0-0.0-0.10.1-0.10.10.10.00.10.2-0.0-0.10.2-0.10.3-0.3-0.2-0.2
Stereotopy head waving bouts, day 34.14.96.42.5-2.52.5-2.5-2.52.5-2.52.52.42.42.42.22.4-2.42.22.21.20.71.01.0
Stereotopy head waving duration, day 34.65.57.22.6-2.62.6-2.6-2.72.7-2.72.72.62.52.62.52.4-2.52.52.21.50.40.80.8
Locomotion velocity, session 70.90.91.51.1-1.11.0-1.0-1.01.0-1.01.01.01.11.00.81.2-1.20.91.20.30.50.60.6
Locomotion distance, session 70.20.30.8-0.50.5-0.50.50.3-0.30.3-0.3-0.1-0.6-0.2-0.0-0.40.4-0.0-0.60.5-0.9-0.9-0.9
Stereotopy head waving bouts, day 70.40.52.10.5-0.50.6-0.6-0.20.2-0.20.20.00.8-0.0-0.20.1-0.6-0.30.6-1.01.41.41.4
Stereotopy head waving duration, day 70.70.92.70.9-1.01.0-1.0-0.60.6-0.60.50.41.20.30.10.7-0.90.01.1-0.91.61.71.7
Locomotion velocity, session 81.41.74.11.4-1.41.4-1.4-1.01.0-0.90.90.71.70.60.30.9-1.50.21.4-0.92.02.02.0
Locomotion distance, session 80.20.20.50.6-0.50.5-0.5-0.40.4-0.40.40.30.70.30.1-0.0-0.70.20.3-0.20.70.70.7
Degree of sensitization distance0.30.30.5-0.60.6-0.60.60.6-0.60.7-0.7-0.6-0.5-0.7-0.7-0.50.6-0.7-0.4-0.50.1-0.0-0.0
Degree of sensitization stereotypy1.31.43.3-0.90.9-0.90.91.2-1.21.3-1.3-1.4-0.6-1.5-1.6-1.10.8-1.6-0.5-1.81.21.01.0
Conditioned locomotion2.42.84.2-2.02.0-2.02.01.7-1.71.6-1.6-1.4-2.1-1.4-1.1-1.71.9-1.1-1.90.1-1.5-1.6-1.6
Cocaine response after cond. corrected5.66.39.8-2.92.9-3.03.02.7-2.72.7-2.6-2.5-2.9-2.4-2.1-3.12.6-2.1-3.0-0.6-1.5-1.8-1.8
Cocaine response after cond. not corrected6.26.910.1-3.13.1-3.13.12.8-2.82.8-2.7-2.5-3.0-2.5-2.1-3.22.7-2.1-3.1-0.6-1.7-1.9-1.9
Cocaine response before conditioning0.50.61.30.9-0.90.9-0.9-0.90.9-0.90.80.80.80.80.71.1-0.60.71.00.20.50.60.6
Saline control response0.10.20.4-0.40.4-0.40.40.3-0.30.3-0.3-0.3-0.5-0.2-0.2-0.50.6-0.1-0.60.2-0.4-0.5-0.5
Bone: connectivity density0.71.14.60.6-0.50.5-0.50.0-0.00.1-0.1-0.41.0-0.4-0.90.8-0.7-0.81.4-1.82.22.02.0
Bone: cortical apparent density1.01.31.8-1.21.2-1.11.11.3-1.31.3-1.3-1.2-1.2-1.3-1.2-1.41.3-1.3-1.2-0.9-0.0-0.2-0.2
Bone: cortical area0.60.83.2-0.10.1-0.10.10.6-0.70.7-0.7-0.90.2-0.9-1.20.20.1-1.20.7-1.81.61.41.4
Bone: cortical porosity0.70.81.41.0-1.01.0-1.0-0.90.9-0.90.90.81.10.80.61.1-1.10.61.20.00.70.80.8
Bone: cortical porosity0.40.51.40.6-0.60.6-0.6-0.30.3-0.30.30.10.80.1-0.10.7-0.7-0.11.0-0.81.21.21.2
Bone: cortical thickness0.81.32.5-0.91.0-1.01.01.3-1.31.3-1.3-1.4-0.8-1.5-1.6-0.81.0-1.5-0.4-1.60.80.60.6
Bone: cortical thickness0.20.20.8-0.20.2-0.30.30.1-0.10.0-0.00.0-0.40.10.2-0.20.30.3-0.50.7-0.9-0.8-0.8
Bone: cortical tissue density0.71.01.5-1.11.0-1.01.01.1-1.11.1-1.1-1.0-1.1-1.1-0.9-1.21.2-1.1-1.1-0.7-0.1-0.2-0.2
Condit. Reinf. active minus inactive responses3.43.95.12.2-2.22.1-2.1-2.22.2-2.22.32.32.12.22.11.9-2.32.21.71.40.20.40.4
Condit. Reinf. active-inactive response ratio1.61.73.01.3-1.21.2-1.2-1.41.5-1.51.51.61.01.61.71.2-1.21.70.81.6-0.7-0.4-0.5
Condit. Reinf. active responses3.64.46.52.5-2.52.4-2.4-2.32.3-2.32.32.12.52.11.92.2-2.52.02.20.81.01.21.3
Condit. Reinf. inactive responses1.41.62.71.5-1.51.4-1.4-1.21.2-1.11.10.91.60.90.61.4-1.50.71.6-0.31.41.41.5
Incentive salience index mean2.32.84.52.0-2.01.9-1.9-1.81.8-1.81.81.72.01.61.41.7-2.11.51.80.50.91.11.1
Condit. Reinf. lever presses0.91.24.21.0-1.00.9-0.9-0.50.5-0.40.40.21.30.1-0.30.8-1.2-0.21.4-1.32.12.02.0
Condit. Reinf. active minus inactive responses1.72.13.91.2-1.21.2-1.2-1.61.6-1.61.61.80.91.81.91.5-1.11.90.92.0-1.1-0.8-0.8
Condit. Reinf. active-inactive response ratio0.60.73.0-0.40.4-0.40.4-0.00.0-0.10.10.3-0.70.40.7-0.20.40.7-0.71.4-1.7-1.6-1.6
Condit. Reinf. active responses1.92.74.01.7-1.71.7-1.7-1.91.9-1.91.91.91.51.91.82.0-1.61.91.61.5-0.20.00.0
Condit. Reinf. inactive responses1.41.72.71.6-1.51.5-1.5-1.41.4-1.41.41.31.61.31.01.6-1.51.11.60.40.80.90.9
Condit. Reinf. lever presses1.72.34.01.4-1.41.4-1.4-1.71.7-1.81.81.91.01.92.01.6-1.12.01.01.9-0.8-0.6-0.6
Condit. Reinf. lever reinforcers received1.42.03.21.4-1.41.3-1.3-1.61.6-1.61.61.71.21.71.71.7-1.31.81.21.5-0.5-0.3-0.3
Conditioned reinforcement - actives2.42.43.41.7-1.71.7-1.7-1.71.7-1.71.71.61.71.71.71.7-1.81.51.61.00.30.20.5
Conditioned reinforcement - inactives1.11.32.4-1.31.4-1.41.41.1-1.11.1-1.1-0.7-1.4-0.9-0.6-1.41.3-0.5-1.50.2-1.2-0.9-1.3
Conditioned locomotion6.57.910.73.0-3.03.0-3.0-3.23.2-3.23.23.32.83.33.23.0-3.03.12.52.3-0.10.20.3
Patch foraging indifference point 0 sec0.10.20.4-0.40.5-0.50.50.5-0.50.5-0.5-0.4-0.3-0.6-0.6-0.40.4-0.5-0.3-0.50.20.40.1
Patch foraging indifference point AUC0.91.01.51.1-1.11.1-1.1-1.11.1-1.11.21.00.91.21.21.0-1.01.20.80.9-0.1-0.30.0
Delay disc. indifference point, 0s delay4.85.311.2-1.91.9-1.91.92.5-2.52.6-2.6-2.9-1.3-2.9-3.1-2.01.5-3.1-0.9-3.32.01.71.6
Delay disc. indifference point, 16s delay0.10.10.2-0.20.2-0.30.30.3-0.30.3-0.4-0.4-0.2-0.4-0.4-0.30.4-0.3-0.1-0.40.30.20.2
Delay disc. indifference point, 2s delay4.14.57.3-2.02.0-2.02.02.4-2.42.4-2.5-2.6-1.7-2.6-2.7-2.02.1-2.7-1.5-2.61.10.80.8
Delay disc. indifference point, 24s delay0.40.40.7-0.50.6-0.80.80.6-0.70.7-0.7-0.8-0.5-0.7-0.7-0.60.6-0.6-0.4-0.50.1-0.3-0.2
Delay disc. indifference point, 4s delay0.80.82.5-0.40.5-0.60.60.8-0.80.9-0.9-1.1-0.2-1.0-1.3-0.50.4-1.2-0.0-1.61.21.11.1
Delay disc. indifference point, 8s delay1.01.01.5-1.21.2-1.11.11.1-1.11.1-1.1-1.0-1.2-1.0-1.0-1.21.1-0.8-1.1-0.3-0.6-0.5-0.6
Indifference point function ln k0.20.30.5-0.70.7-0.70.70.7-0.70.7-0.6-0.5-0.6-0.6-0.6-0.60.6-0.6-0.6-0.3-0.2-0.1-0.3
Indifference point function log k0.20.30.5-0.70.7-0.70.70.7-0.70.7-0.6-0.5-0.6-0.6-0.6-0.60.6-0.6-0.6-0.3-0.2-0.1-0.3
Patch foraging total patch changes 0 sec0.10.20.3-0.50.5-0.50.50.5-0.50.5-0.5-0.4-0.4-0.5-0.5-0.40.4-0.5-0.3-0.3-0.00.3-0.1
Patch foraging total patch changes 12 sec0.50.61.0-0.90.9-1.01.00.7-0.70.7-0.7-0.7-1.0-0.6-0.5-0.80.9-0.3-1.00.2-0.8-0.9-0.9
Patch foraging total patch changes 18 sec0.70.91.31.0-1.11.1-1.1-1.11.1-1.11.11.20.91.11.21.1-0.91.10.80.8-0.1-0.10.1
Patch foraging total patch changes 24 sec0.10.10.20.5-0.50.4-0.4-0.40.4-0.40.40.20.30.40.20.4-0.20.30.30.10.30.10.3
Patch foraging total patch changes 6 sec0.10.20.40.5-0.40.3-0.3-0.40.4-0.40.40.60.40.40.40.3-0.40.60.30.4-0.10.3-0.1
Patch foraging time to switch 0 sec1.11.73.8-0.91.0-1.11.11.4-1.41.4-1.5-1.6-0.7-1.6-1.9-0.90.9-1.7-0.4-1.91.21.21.0
Patch foraging water rate 0 sec0.40.62.4-0.40.4-0.50.50.1-0.10.00.10.3-0.50.20.5-0.50.40.5-0.91.2-1.5-1.6-1.5
Patch foraging water rate 12 sec1.52.43.8-1.91.9-1.71.71.5-1.51.4-1.4-1.2-1.9-1.2-0.8-1.81.6-1.0-1.90.2-1.6-1.7-1.6
Patch foraging water rate 18 sec1.31.77.3-0.80.8-0.80.80.1-0.10.10.00.3-1.20.30.8-0.80.90.8-1.62.1-2.7-2.6-2.5
Patch foraging water rate 24 sec2.43.410.1-1.81.8-1.91.91.1-1.11.0-0.9-0.4-2.1-0.60.1-1.81.80.1-2.51.8-3.2-2.9-3.1
Patch foraging water rate 6 sec0.71.03.9-0.20.2-0.10.1-0.40.4-0.50.50.8-0.50.81.1-0.00.21.0-0.71.9-2.0-1.7-1.8
Seeking ratio, delayed vs. immediate footshock4.65.37.32.6-2.62.6-2.6-2.62.6-2.62.62.62.42.52.32.7-2.02.32.31.30.71.10.9
Distance traveled before self-admin0.10.20.4-0.20.2-0.20.20.4-0.40.4-0.4-0.5-0.2-0.5-0.6-0.20.4-0.4-0.1-0.70.50.50.4
Distance traveled after self-admin1.01.11.61.3-1.21.1-1.1-1.21.2-1.21.21.01.11.10.91.2-1.01.11.00.60.30.70.4
Extensor digitorum longus weight4.216.422.5-4.74.7-4.64.64.6-4.64.5-4.5-4.3-4.6-4.3-3.9-4.14.6-3.9-4.0-1.9-1.6-2.2-2.1
Bone: elastic displacement0.30.30.40.6-0.60.7-0.7-0.60.6-0.60.60.60.60.60.60.4-0.70.50.40.30.10.20.2
Bone: elastic work0.10.20.6-0.10.1-0.10.10.4-0.40.4-0.4-0.4-0.0-0.5-0.6-0.30.1-0.5-0.0-0.80.70.60.6
Bone: endosteal estimation0.20.41.2-0.30.3-0.20.20.5-0.50.6-0.6-0.6-0.0-0.7-0.8-0.20.2-0.90.1-1.10.90.80.8
Bone: endosteal perimeter0.61.22.51.1-1.21.3-1.3-0.90.9-0.80.80.71.40.60.41.3-1.30.31.6-0.51.41.41.4
Epididymis fat weight0.10.31.00.4-0.30.3-0.3-0.50.5-0.50.60.50.00.60.80.3-0.20.80.01.0-0.8-0.8-0.7
Delta time in closed arm before/after self-admin2.22.16.4-1.41.4-1.41.41.0-1.00.9-0.9-0.7-1.9-0.6-0.3-1.41.8-0.2-2.01.0-2.1-2.5-2.2
Delta time in open arm before/after self-admin1.01.01.5-1.01.0-1.01.01.2-1.11.2-1.1-1.1-0.8-1.2-1.2-1.00.8-1.2-0.7-1.00.30.50.2
Diff in mean of infusions in LGA sessions1.21.31.91.2-1.21.2-1.2-1.31.3-1.31.31.31.11.41.41.2-1.21.31.01.0-0.20.10.0
Delay discount exponential model param1.31.42.31.1-1.11.2-1.2-1.31.3-1.41.41.51.01.41.51.2-1.11.40.81.4-0.5-0.4-0.3
Extinction: sum of active levers before priming1.00.92.70.6-0.60.5-0.5-0.90.9-0.91.01.10.21.11.40.6-0.51.30.11.7-1.3-1.3-1.1
Active lever presses in extinction session 62.72.73.81.8-1.81.8-1.8-1.81.8-1.81.81.81.71.81.81.8-2.01.71.61.10.20.30.5
Bone: final force0.81.33.8-0.60.6-0.70.71.1-1.11.2-1.2-1.4-0.4-1.4-1.7-0.40.7-1.60.1-2.01.41.21.2
Bone: final moment0.71.13.3-0.50.5-0.60.61.0-1.01.1-1.1-1.2-0.3-1.3-1.5-0.30.5-1.40.2-1.81.41.11.1
Food consumed during 24 hour testing period0.40.50.6-0.80.8-0.80.80.8-0.80.8-0.8-0.8-0.7-0.8-0.8-0.80.7-0.8-0.7-0.5-0.1-0.2-0.2
Glucose1.01.52.1-1.31.3-1.41.41.4-1.41.4-1.4-1.4-1.3-1.3-1.3-1.41.3-1.2-1.3-0.7-0.2-0.4-0.4
Heart weight0.30.41.20.5-0.50.4-0.4-0.60.6-0.70.70.60.20.80.90.3-0.31.00.01.1-0.8-0.7-0.7
Delay discount hyperbolic model param1.92.03.31.3-1.41.4-1.4-1.61.6-1.61.71.81.21.71.81.4-1.41.71.01.6-0.6-0.5-0.4
Intermittent access intake day 1-15 change4.94.88.12.1-2.12.2-2.2-2.52.5-2.62.62.81.92.72.82.2-2.12.61.62.4-0.7-0.3-0.3
Intermittent access intake escalation4.34.28.91.6-1.61.7-1.7-2.22.3-2.32.32.81.22.63.01.7-1.42.70.83.0-1.7-1.3-1.3
Intermittent access intake escalation 25.45.310.22.0-2.02.1-2.1-2.62.6-2.72.73.01.52.93.22.1-1.83.01.23.1-1.6-1.3-1.1
Intermitt. access day 1 inactive lever presses0.40.41.40.3-0.30.3-0.3-0.50.5-0.60.60.70.10.70.90.3-0.41.0-0.11.2-1.0-0.8-0.9
Intermitt. access day 15 inactive lever presses0.30.30.90.3-0.30.2-0.2-0.50.5-0.50.50.80.30.60.80.2-0.70.90.10.9-0.7-0.4-0.6
Intermitt. access escalation Index0.60.52.30.3-0.30.2-0.20.2-0.20.2-0.2-0.50.5-0.4-0.70.2-0.2-0.70.7-1.41.51.01.4
Intermittent access day 1 total infusions0.10.10.2-0.20.2-0.30.30.3-0.30.4-0.4-0.2-0.3-0.4-0.2-0.30.4-0.3-0.2-0.40.20.10.1
Intermittent access day 15 total infusions1.11.22.90.8-0.90.9-0.9-1.21.2-1.21.21.60.61.31.70.9-0.71.50.41.6-0.9-0.8-0.7
Intermittent access terminal intake (last 3 days)0.80.81.60.9-1.01.0-1.0-1.11.1-1.11.01.10.81.11.31.0-0.91.00.80.8-0.1-0.10.1
Intermittent access total infusions0.10.10.40.1-0.10.1-0.1-0.20.2-0.30.20.50.00.30.60.1-0.10.4-0.10.6-0.5-0.3-0.4
Intermittent access day 1 locomotion0.20.20.50.3-0.20.2-0.2-0.40.4-0.40.40.70.10.40.70.2-0.20.60.00.6-0.5-0.3-0.4
Intermittent access day 15 total locomotion2.32.44.91.4-1.41.5-1.5-1.81.8-1.81.82.21.21.92.21.5-1.41.91.01.8-0.7-0.2-0.5
Intermittent access total locomotion0.70.81.50.8-0.90.9-0.9-1.01.0-1.01.01.20.71.01.20.9-0.81.00.60.9-0.20.1-0.1
Intermittent access standard deviation2.32.54.51.4-1.41.5-1.5-1.81.8-1.81.81.91.31.92.11.5-1.61.91.11.8-0.7-0.8-0.4
Left kidney weight0.20.61.70.8-0.80.8-0.8-0.50.5-0.50.50.21.00.30.00.8-0.80.11.1-0.71.30.81.3
Right kidney weight1.43.85.32.2-2.22.2-2.2-2.22.2-2.22.22.02.12.11.92.3-2.22.02.11.10.50.60.7
Cocaine induced anxiety1.41.62.71.5-1.51.5-1.5-1.21.2-1.21.20.81.51.00.61.5-1.40.81.7-0.21.31.21.4
Post-drug Anxiety1.51.73.71.6-1.51.5-1.5-1.11.0-1.01.00.41.50.70.31.5-1.30.51.8-0.81.91.31.9
Baseline Anxiety0.10.10.5-0.20.2-0.20.20.0-0.00.0-0.00.1-0.20.10.2-0.20.10.2-0.30.5-0.6-0.7-0.6
Tail length2.36.911.02.6-2.62.7-2.7-3.03.0-3.03.13.32.33.23.32.5-2.53.21.82.8-0.9-0.4-0.5
Length with tail1.55.68.42.6-2.62.7-2.7-2.72.7-2.72.72.92.42.72.62.3-2.52.62.01.80.10.90.4
Length without tail0.20.52.70.8-0.70.7-0.7-0.40.4-0.40.40.50.90.20.00.6-0.70.10.8-0.61.11.61.0
Times rat made contact with spout0.30.40.8-0.70.7-0.80.80.5-0.50.5-0.5-0.4-0.7-0.4-0.3-0.40.5-0.2-0.60.3-0.9-0.9-0.9
Lifetime Intake0.00.00.10.1-0.10.1-0.1-0.10.1-0.10.10.30.10.10.40.1-0.10.10.00.1-0.0-0.2-0.0
Liver weight, left2.23.54.6-2.22.1-2.12.12.1-2.12.1-2.1-2.1-2.1-2.0-1.8-1.92.1-1.8-1.8-1.0-0.6-1.1-0.9
Liver weight, right1.32.23.1-1.61.6-1.51.51.7-1.71.7-1.7-1.8-1.4-1.8-1.7-1.51.5-1.8-1.2-1.30.2-0.0-0.0
Locomotor activity3.45.58.12.7-2.72.7-2.7-2.52.5-2.52.42.52.72.32.02.8-2.52.02.70.81.21.81.4
Locomotor testing distance1.83.14.22.1-2.12.0-2.0-1.91.9-1.91.91.92.01.81.71.9-1.81.61.80.70.81.10.9
Locomotor testing rearing0.00.00.10.0-0.00.0-0.0-0.10.1-0.10.10.1-0.10.10.3-0.10.10.2-0.20.3-0.3-0.3-0.3
Locomotion in novel chamber0.40.50.80.7-0.70.5-0.5-0.80.8-0.80.80.60.60.90.90.7-0.60.90.50.8-0.3-0.7-0.4
Locomotion in novel chamber post-restriction0.50.61.00.8-0.91.0-1.0-0.90.9-0.90.90.80.60.90.91.0-0.60.80.80.60.1-0.10.2
Fecal boli incidents, locomotor time 12.12.33.9-1.61.6-1.71.71.6-1.61.6-1.5-1.4-1.7-1.5-1.2-1.91.9-1.0-2.0-0.3-1.0-1.2-1.0
Change in fecal boli incidents, locomotor task1.11.02.10.9-1.01.2-1.2-0.80.8-0.70.70.51.20.50.31.1-1.20.11.4-0.61.41.41.4
Time >=10cm from walls, locomotor time 10.40.41.4-0.10.2-0.20.20.4-0.40.4-0.5-0.60.2-0.6-0.7-0.3-0.2-0.70.2-1.21.11.01.0
Bouts of movement, locomotor time 10.10.10.30.4-0.40.3-0.3-0.30.4-0.40.40.40.40.40.50.2-0.50.60.20.4-0.2-0.2-0.2
Total resting periods, locomotor time 10.20.20.30.6-0.50.4-0.4-0.50.5-0.50.50.60.60.50.50.4-0.60.60.40.30.10.10.1
Rest time, locomotor task time 10.20.20.40.5-0.50.5-0.5-0.40.4-0.40.50.40.60.40.40.4-0.60.30.5-0.00.40.40.3
Distance moved, locomotor task time 10.40.41.5-0.20.2-0.20.20.4-0.40.4-0.5-0.60.1-0.6-0.8-0.0-0.0-0.80.4-1.21.11.21.0
Vertical activity count, locomotor time 10.10.10.2-0.30.3-0.30.30.2-0.20.2-0.2-0.2-0.3-0.2-0.2-0.20.3-0.0-0.30.2-0.4-0.2-0.4
Time >=10cm from walls, locomotor time 21.21.31.9-1.31.3-1.41.41.2-1.21.2-1.2-1.1-1.4-1.1-0.9-1.21.4-1.0-1.2-0.4-0.6-0.7-0.8
Bouts of movement, locomotor time 20.90.92.11.0-1.01.0-1.0-0.80.8-0.80.80.61.30.60.40.9-1.50.41.3-0.41.11.21.2
Total resting periods, locomotor time 20.91.02.31.1-1.11.0-1.0-0.80.8-0.80.70.51.40.60.30.9-1.50.41.4-0.51.31.31.3
Rest time, locomotor task time 20.70.81.41.1-1.10.9-0.9-0.90.9-0.90.80.71.20.70.61.0-1.10.61.1-0.10.90.80.9
Distance moved, locomotor task time 21.01.21.8-1.31.3-1.31.31.1-1.11.1-1.1-0.9-1.3-1.0-0.8-1.21.1-0.9-1.2-0.1-0.9-0.8-1.0
Vertical activity count, locomotor time 21.41.52.4-1.51.4-1.31.31.2-1.21.1-1.1-0.9-1.5-0.9-0.6-1.41.3-0.7-1.50.3-1.4-1.4-1.6
Light reinforcement 14.68.411.73.2-3.23.1-3.1-3.33.4-3.43.33.43.03.33.13.1-3.13.22.62.20.20.60.5
Light reinforcement 21.31.82.91.4-1.41.5-1.5-1.51.5-1.51.51.71.41.51.51.5-1.31.41.31.00.10.50.2
Bone: marrow area0.20.41.2-0.30.3-0.20.20.6-0.60.6-0.6-0.7-0.1-0.7-0.8-0.20.2-0.90.1-1.10.90.70.7
Bone: maximum diameter1.22.24.51.7-1.71.7-1.7-1.31.3-1.21.21.11.81.00.71.9-1.60.62.1-0.51.71.81.8
Bone: maximum force0.81.43.5-0.90.9-0.90.91.3-1.31.4-1.4-1.5-0.6-1.5-1.7-0.60.8-1.7-0.1-1.91.20.90.9
Bone: maximum moment0.71.23.1-0.80.8-0.80.81.2-1.21.2-1.2-1.4-0.5-1.4-1.6-0.60.7-1.6-0.1-1.81.10.90.9
Mean time between licks in bursts2.84.06.42.0-2.02.1-2.1-2.32.3-2.32.32.51.72.42.51.8-1.82.51.32.2-0.8-0.5-0.5
Mean num. licks in bursts0.10.10.30.2-0.20.1-0.1-0.10.1-0.10.1-0.10.30.0-0.2-0.2-0.3-0.10.1-0.40.50.50.5
Cd content in liver0.10.10.3-0.30.3-0.30.30.4-0.40.4-0.4-0.5-0.4-0.4-0.5-0.10.6-0.5-0.1-0.40.20.10.1
Co content in liver0.40.51.10.6-0.60.5-0.5-0.70.7-0.80.80.90.30.90.90.9-0.40.90.51.0-0.6-0.4-0.5
Cu content in liver0.30.41.60.2-0.20.2-0.20.0-0.00.1-0.1-0.20.5-0.3-0.50.3-0.4-0.50.7-1.01.21.31.2
Fe content in liver0.10.10.6-0.20.2-0.20.20.0-0.00.00.00.1-0.30.10.2-0.10.10.2-0.30.5-0.7-0.7-0.7
K content in liver0.40.41.40.5-0.50.5-0.5-0.30.3-0.20.20.10.70.0-0.20.3-0.6-0.20.6-0.81.21.11.1
Mg content in liver0.60.62.30.7-0.70.6-0.6-0.30.3-0.30.20.00.90.0-0.20.5-0.8-0.21.0-1.01.51.41.4
Mn content in liver2.93.36.92.0-2.02.0-2.0-1.51.4-1.41.31.02.41.00.51.6-2.20.52.3-1.12.62.52.6
Na content in liver0.70.71.7-0.70.7-0.70.70.9-0.90.9-1.0-1.0-0.4-1.1-1.2-0.80.5-1.2-0.4-1.30.80.70.6
Rb content in liver0.50.62.40.1-0.10.0-0.00.4-0.40.4-0.4-0.70.2-0.7-0.9-0.10.1-0.90.4-1.51.61.31.4
Se content in liver0.20.20.50.5-0.50.5-0.5-0.60.6-0.50.50.50.60.50.40.4-0.70.40.50.20.30.30.3
Sr content in liver0.50.51.8-0.40.4-0.50.50.2-0.20.1-0.10.0-0.70.10.3-0.40.60.3-0.81.0-1.4-1.3-1.3
Zn content in liver1.61.85.90.7-0.70.6-0.6-1.21.2-1.31.31.50.21.61.90.7-0.61.9-0.02.4-2.0-1.7-1.7
Bone: minimum diameter0.20.41.50.4-0.40.4-0.4-0.10.1-0.00.0-0.10.6-0.2-0.30.5-0.4-0.30.8-0.91.21.11.1
Time in familiar zone, hab. session 11.61.52.51.2-1.21.2-1.2-1.41.4-1.41.41.51.01.51.51.1-1.11.60.81.4-0.5-0.3-0.3
Time in novel zone, hab. session 10.80.82.5-0.50.5-0.50.50.8-0.80.8-0.9-1.0-0.1-1.0-1.2-0.10.3-1.20.3-1.61.31.21.2
Total zone transitions, hab. session 11.41.93.21.6-1.61.6-1.6-1.41.4-1.31.31.01.81.10.71.2-1.70.81.5-0.31.51.61.6
Total locomotion distance, hab. session 12.43.46.42.1-2.12.0-2.0-1.61.6-1.51.51.12.41.20.61.7-2.20.82.3-0.82.42.52.5
Locomotion velocity, hab. session 12.33.35.52.1-2.12.1-2.1-1.81.8-1.71.71.42.41.51.01.8-2.31.12.1-0.31.92.12.1
Time in familiar zone, hab. session 24.64.78.02.1-2.12.1-2.1-2.52.5-2.52.52.71.62.72.82.1-1.92.81.42.7-1.1-0.8-0.8
Time in novel zone, hab. session 23.33.36.1-1.61.6-1.61.62.0-2.02.0-2.1-2.2-1.2-2.2-2.4-1.61.4-2.4-0.9-2.51.31.01.0
Total zone transitions, hab. session 20.60.83.60.4-0.30.2-0.20.1-0.10.1-0.2-0.50.7-0.4-0.9-0.5-0.6-0.70.3-1.61.91.81.8
Total locomotion distance, hab. session 21.21.62.91.6-1.51.4-1.4-1.31.3-1.31.21.01.71.10.70.7-1.70.91.1-0.21.31.41.4
Locomotion velocity, hab. session 21.41.93.51.7-1.61.5-1.5-1.31.3-1.31.20.91.91.00.60.8-1.80.71.3-0.51.71.81.8
Novel to familiar place preference ratio2.72.86.3-1.31.3-1.31.31.7-1.81.8-1.8-2.0-0.9-2.0-2.2-1.51.1-2.3-0.8-2.51.61.31.3
Novelty place preference1.61.64.3-0.90.9-0.90.91.3-1.31.3-1.4-1.5-0.5-1.5-1.7-1.10.8-1.8-0.5-2.11.51.31.3
Time in novel zone, NPP test1.81.84.4-1.01.0-1.01.01.4-1.41.5-1.5-1.7-0.7-1.7-1.8-1.20.9-1.9-0.6-2.11.41.21.2
Total zone transitions, NPP test0.20.20.90.3-0.30.2-0.2-0.10.1-0.10.0-0.10.5-0.1-0.4-0.4-0.4-0.20.0-0.71.00.90.9
Total locomotion distance, NPP test0.30.52.00.5-0.40.3-0.3-0.10.1-0.10.0-0.20.7-0.1-0.5-0.1-0.6-0.30.4-1.01.41.41.4
Locomotion velocity, NPP test0.40.51.80.7-0.70.6-0.6-0.40.4-0.40.30.11.00.2-0.20.1-0.9-0.00.6-0.81.31.31.3
Intraocular pressure0.40.62.9-0.30.3-0.40.40.0-0.0-0.00.10.1-0.70.30.5-0.40.60.6-0.81.2-1.5-1.7-1.5
Delta distance traveled before/after self-admin1.31.42.01.3-1.31.3-1.3-1.41.4-1.41.41.41.21.41.31.3-1.21.31.10.90.00.50.2
Delta ambulatory time before/after self-admin1.71.92.61.6-1.61.5-1.5-1.51.5-1.51.51.41.51.41.31.6-1.51.31.50.60.50.60.7
Parametrial fat weight0.30.61.20.7-0.70.7-0.7-0.80.9-0.90.91.10.50.91.10.9-0.61.10.51.0-0.5-0.2-0.4
Pavlov. Cond. lever latency0.40.51.9-0.50.5-0.50.50.2-0.20.1-0.10.1-0.70.10.3-0.40.60.3-0.81.0-1.4-1.4-1.3
Pavlov. Cond. magazine entry latency1.92.53.71.7-1.71.7-1.7-1.81.8-1.91.91.91.51.91.91.4-1.61.91.11.6-0.3-0.1-0.1
Pavlov. Cond. change in total contacts0.10.10.10.3-0.30.3-0.3-0.30.3-0.30.30.30.30.30.20.0-0.40.30.10.10.10.10.2
Pavlov. Cond. index score0.50.71.21.0-1.00.9-0.9-0.80.8-0.80.80.71.10.70.50.7-1.10.50.9-0.10.80.90.9
Pavlov. Cond. latency score0.70.91.71.1-1.11.1-1.1-0.80.8-0.80.80.61.30.60.40.8-1.20.41.1-0.41.21.31.3
Pavlov. Cond. lever contacts0.70.82.70.8-0.80.8-0.8-0.50.5-0.40.40.21.10.2-0.10.8-1.0-0.11.2-1.01.61.61.6
Pavlov. Cond. magazine entry number0.40.60.8-0.80.8-0.80.80.9-0.90.9-0.9-0.9-0.8-0.9-0.8-0.60.9-0.8-0.6-0.6-0.0-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.20.21.0-0.00.0-0.10.1-0.10.1-0.10.20.3-0.30.30.40.00.20.6-0.30.9-1.0-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.01.71.2-1.21.2-1.2-1.11.1-1.01.00.91.30.90.80.9-1.30.81.10.10.80.90.9
Pavlov. Cond. response bias0.81.01.41.1-1.11.1-1.1-1.21.2-1.21.21.11.11.11.11.0-1.21.10.90.70.10.30.3
Pavlov. Cond. lever latency0.81.11.7-1.21.2-1.21.21.2-1.21.2-1.2-1.2-0.9-1.2-1.1-1.30.7-1.1-1.1-0.7-0.2-0.3-0.3
Pavlov. Cond. magazine entry latency0.60.71.30.9-0.91.0-1.0-0.90.9-0.80.90.80.80.80.81.2-0.70.61.10.20.50.60.6
Pavlov. Cond. change in total contacts0.81.11.61.1-1.11.1-1.1-1.21.2-1.21.21.20.91.21.21.3-0.91.20.91.0-0.2-0.0-0.0
Pavlov. Cond. index score0.91.11.91.1-1.21.2-1.2-1.21.2-1.21.21.20.91.21.21.4-0.81.11.10.80.10.20.2
Pavlov. Cond. latency score0.91.12.11.1-1.21.2-1.2-1.11.1-1.11.21.11.01.11.11.4-0.91.01.20.50.30.50.5
Pavlov. Cond. lever contacts0.60.91.41.0-1.01.0-1.0-1.11.1-1.11.11.10.71.11.21.0-0.61.20.71.0-0.3-0.1-0.1
Pavlov. Cond. magazine entry number0.91.11.9-1.21.2-1.31.31.2-1.21.2-1.2-1.1-1.1-1.1-1.0-1.40.9-0.9-1.2-0.4-0.5-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.71.02.1-1.11.1-1.21.20.9-0.90.9-0.9-0.7-1.1-0.8-0.7-1.41.1-0.6-1.50.1-0.8-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.91.22.01.2-1.21.3-1.3-1.21.2-1.21.21.21.01.21.21.4-0.91.11.20.60.30.40.4
Pavlov. Cond. response bias1.52.03.21.5-1.51.5-1.5-1.61.6-1.71.71.71.11.71.81.6-1.11.71.11.4-0.4-0.1-0.1
Time in closed arm before self-admin0.70.82.2-0.50.5-0.50.50.8-0.80.8-0.9-0.9-0.2-1.0-1.2-0.50.5-1.2-0.0-1.51.21.51.1
Time in closed arm after self-admin0.00.00.20.2-0.20.1-0.1-0.20.2-0.20.20.0-0.10.20.00.10.40.3-0.10.2-0.1-0.3-0.1
Time in open arm before self-admin0.91.01.50.9-0.90.9-0.9-1.11.1-1.11.11.10.91.21.21.0-1.11.20.71.1-0.4-0.4-0.3
Time in open arm after self-admin0.70.81.3-1.21.1-1.11.11.0-1.01.0-1.0-0.8-0.9-1.0-0.8-1.10.5-0.9-0.9-0.4-0.4-0.2-0.5
Bone: periosteal estimation0.40.93.4-0.00.0-0.00.00.6-0.60.6-0.6-0.80.3-0.9-1.20.20.0-1.20.7-1.81.81.61.6
Bone: periosteal perimeter0.61.03.10.9-0.91.0-1.0-0.50.5-0.40.40.31.20.2-0.11.2-0.9-0.21.6-1.11.81.71.7
Bone: post-yield work0.50.71.1-0.90.9-0.90.91.0-1.01.0-1.0-1.0-0.9-1.0-1.0-0.70.9-0.9-0.6-0.70.0-0.1-0.1
Progressive ratio test 1 active lever presses0.30.30.5-0.60.6-0.70.70.5-0.50.5-0.5-0.3-0.7-0.4-0.2-0.70.7-0.2-0.70.1-0.5-0.6-0.5
Progressive ratio test 1 breakpoint0.30.30.6-0.60.6-0.70.70.6-0.60.6-0.6-0.5-0.7-0.5-0.3-0.70.8-0.3-0.7-0.1-0.3-0.5-0.4
Progressive ratio test 1 inactive lever presses0.00.00.00.0-0.00.0-0.0-0.00.0-0.00.00.10.00.00.10.0-0.00.10.00.00.00.0-0.0
Progressive ratio test 2 active lever presses0.20.20.50.2-0.20.2-0.2-0.40.4-0.40.40.50.10.50.70.2-0.30.50.00.7-0.6-0.6-0.5
Progressive ratio test 2 breakpoint0.20.30.50.5-0.50.6-0.6-0.60.6-0.60.60.60.60.60.70.6-0.70.50.50.40.0-0.20.1
Progressive ratio test 2 inactive lever presses0.10.10.20.3-0.30.2-0.2-0.20.2-0.20.20.30.30.20.30.2-0.40.20.30.00.20.20.2
Incentive Sensitization - Responses0.30.30.60.4-0.40.4-0.4-0.50.5-0.60.60.50.30.60.80.4-0.60.70.20.8-0.5-0.6-0.4
Incentive Sensitization - Breakpoint0.30.40.60.5-0.60.6-0.6-0.70.7-0.70.70.60.50.70.80.6-0.70.70.40.7-0.3-0.4-0.1
Sum of active levers in priming session hrs 5-60.00.00.2-0.10.1-0.20.20.1-0.10.1-0.1-0.0-0.3-0.10.1-0.10.4-0.0-0.20.1-0.2-0.4-0.2
Progressive ratio0.20.20.8-0.50.5-0.50.50.4-0.50.4-0.4-0.5-0.4-0.3-0.2-0.5-0.0-0.2-0.50.1-0.5-0.9-0.6
Food seeking constrained by brief footshock0.10.10.20.4-0.30.3-0.3-0.40.4-0.40.30.30.30.40.20.5-0.30.40.40.3-0.0-0.10.1
Seeking ratio, punishment vs. effort0.10.10.30.3-0.30.3-0.3-0.30.3-0.30.30.40.20.30.10.40.20.20.30.00.30.50.3
Retroperitoneal fat weight0.61.93.3-1.61.6-1.61.61.5-1.51.5-1.4-1.1-1.6-1.4-1.1-1.81.6-1.1-1.8-0.3-0.9-0.7-1.0
Reaction time number correct1.01.42.4-1.41.4-1.41.41.1-1.11.0-1.0-0.9-1.5-0.8-0.6-1.41.3-0.6-1.50.3-1.3-1.5-1.3
Reaction time mean minus median0.71.01.51.2-1.21.2-1.2-1.11.1-1.11.21.01.01.11.01.0-0.81.00.90.50.30.30.5
Reaction time mean minus median AUC0.60.83.20.8-0.90.9-0.9-0.40.4-0.30.40.11.10.1-0.10.5-0.6-0.21.0-1.21.81.51.7
Reaction time num false alarms0.10.10.4-0.30.3-0.30.30.2-0.20.2-0.2-0.3-0.4-0.2-0.1-0.40.1-0.1-0.40.2-0.4-0.6-0.4
Reaction time num false alarms AUC0.20.31.2-0.60.6-0.60.60.4-0.40.4-0.4-0.4-0.7-0.3-0.1-0.70.5-0.1-0.80.4-0.8-1.1-0.8
Reaction time trials correct on left1.01.42.4-1.41.4-1.41.41.1-1.11.0-1.0-0.9-1.5-0.8-0.6-1.41.3-0.6-1.50.3-1.3-1.5-1.3
Reaction time trials on left0.91.32.2-1.41.4-1.31.31.1-1.11.0-1.0-0.9-1.4-0.9-0.6-1.31.2-0.7-1.50.2-1.2-1.4-1.2
Reaction time mean0.30.41.90.6-0.60.6-0.6-0.20.2-0.10.2-0.10.6-0.1-0.30.4-0.2-0.30.7-1.01.41.31.3
Reaction time mean AUC0.30.41.70.4-0.40.4-0.4-0.00.0-0.00.0-0.10.5-0.2-0.40.3-0.1-0.40.6-1.01.31.21.2
Median of all reaction times0.40.51.8-0.00.0-0.00.00.4-0.40.4-0.4-0.60.2-0.6-0.8-0.10.2-0.80.3-1.41.31.31.2
Reaction time omissions0.20.30.60.7-0.70.7-0.7-0.60.6-0.60.60.60.60.50.50.5-0.50.40.50.10.40.40.5
Reaction time false alarm rate0.00.00.00.1-0.10.1-0.10.0-0.00.0-0.0-0.10.0-0.0-0.1-0.1-0.1-0.00.0-0.20.20.00.2
Reaction time premature initiation rate0.60.82.50.6-0.60.6-0.6-0.90.9-0.91.01.20.41.11.30.4-0.71.3-0.01.6-1.2-0.7-1.0
Reaction time premature initiations0.70.93.8-0.10.1-0.10.1-0.40.4-0.50.50.8-0.40.81.1-0.30.01.1-0.91.9-1.9-1.6-1.8
Std. dev. reaction times0.40.61.01.0-1.01.0-1.0-0.70.7-0.70.80.51.00.60.50.6-0.70.50.8-0.20.90.71.0
Reaction time trials completed0.91.32.2-1.41.4-1.31.31.1-1.11.0-1.0-0.9-1.4-0.9-0.6-1.31.2-0.7-1.50.2-1.2-1.4-1.2
Reaction time trials AUC1.11.52.7-1.51.4-1.41.41.1-1.11.0-1.0-0.9-1.5-0.8-0.5-1.41.3-0.6-1.60.5-1.5-1.6-1.5
Run reversals in cocaine runway, females1.11.12.11.2-1.21.1-1.1-1.11.1-1.11.00.71.41.00.51.3-1.40.81.40.10.81.01.0
Run reversals in cocaine runway, males1.41.32.31.5-1.41.4-1.4-1.31.3-1.31.21.01.21.20.91.5-0.91.01.40.30.80.60.9
Latency to leave start box in cocaine runway1.61.73.01.5-1.51.5-1.5-1.21.2-1.21.21.11.70.90.81.5-1.40.61.7-0.41.51.51.5
Latency to leave start box in cocaine runway, F1.11.25.10.8-0.80.8-0.8-0.30.3-0.30.2-0.01.2-0.1-0.40.9-0.8-0.51.4-1.62.32.02.2
Latency to leave start box in cocaine runway, M2.12.04.11.2-1.21.2-1.2-1.51.5-1.51.61.81.01.72.01.1-1.21.90.52.0-1.2-1.0-1.0
Std. dev. time between licks in bursts1.21.42.51.3-1.31.3-1.3-1.21.1-1.11.11.01.51.00.71.4-1.40.71.6-0.11.11.21.2
Total sessions with >9 infusions0.30.31.20.5-0.50.5-0.5-0.20.2-0.20.2-0.10.60.0-0.10.5-0.4-0.20.8-0.71.10.61.1
Short access day 1 total inactive lever presses0.00.00.10.1-0.10.1-0.1-0.20.2-0.20.20.20.00.20.20.10.10.20.00.2-0.1-0.3-0.0
Short access day 10 total inactive lever presses0.20.20.8-0.10.1-0.20.2-0.10.1-0.10.10.3-0.30.20.4-0.20.10.5-0.40.8-0.9-0.8-0.8
Short access day 1 total infusions0.40.41.30.7-0.70.7-0.7-0.40.4-0.40.30.20.60.20.20.7-0.3-0.10.8-0.61.10.81.1
Short access day 10 total infusions0.00.00.1-0.00.0-0.00.00.0-0.00.0-0.00.0-0.1-0.00.2-0.00.1-0.1-0.0-0.00.0-0.30.1
Short access total infusions0.10.10.60.3-0.30.3-0.3-0.10.1-0.10.0-0.10.3-0.00.00.3-0.1-0.20.4-0.60.80.20.8
Short access day 1 locomotion0.70.71.30.9-0.90.9-0.9-0.90.9-0.90.81.11.00.80.90.9-0.90.60.90.30.50.90.5
Short access day 10 total locomotion2.83.25.81.6-1.61.7-1.7-2.02.0-2.12.02.41.52.22.41.7-1.82.21.22.1-0.8-0.3-0.5
Short access total locomotion0.70.71.20.9-0.91.0-1.0-1.01.0-1.00.91.10.90.91.11.0-0.80.80.80.50.20.40.3
One hour access (0.3 mA shock)0.30.30.5-0.70.7-0.70.70.6-0.60.6-0.6-0.4-0.5-0.6-0.4-0.70.5-0.5-0.6-0.2-0.2-0.2-0.3
Compulsive drug intake0.60.61.4-0.70.7-0.70.70.8-0.80.9-0.8-1.0-0.6-0.9-1.2-0.70.8-0.9-0.5-0.90.40.40.2
One hour access (shock baseline)0.10.20.6-0.30.3-0.30.30.1-0.10.1-0.10.3-0.30.10.4-0.30.10.2-0.50.6-0.8-0.8-0.7
Social response proportion0.70.81.71.0-1.01.1-1.1-0.90.9-0.90.90.71.10.90.70.9-1.30.71.00.20.50.60.6
Social responses7.39.413.13.5-3.63.6-3.6-3.43.4-3.43.43.13.43.33.03.3-3.52.93.11.41.21.41.5
Social time0.81.02.0-1.21.2-1.11.11.1-1.11.1-1.1-0.9-1.1-1.0-0.9-1.41.0-0.9-1.3-0.4-0.4-0.4-0.5
Soleus weight7.120.828.4-5.05.0-4.94.95.3-5.35.3-5.3-5.3-4.6-5.3-5.2-4.54.9-5.2-3.8-3.7-0.0-0.8-0.8
Bone: stiffness2.03.26.1-1.71.7-1.81.82.1-2.12.2-2.2-2.3-1.4-2.3-2.5-1.11.6-2.3-0.7-2.20.90.50.5
Tibialis anterior weight0.72.43.4-1.71.7-1.61.61.8-1.81.8-1.8-1.8-1.6-1.8-1.8-1.01.8-1.8-1.0-1.30.1-0.2-0.1
Time to tail flick, vehicle, before self-admin1.41.42.71.4-1.41.4-1.4-1.11.1-1.01.00.71.30.80.51.4-0.80.51.5-0.51.51.31.7
Time to tail flick, vehicle, after self-admin0.20.21.0-0.00.0-0.10.1-0.20.2-0.20.30.1-0.20.40.4-0.1-0.10.6-0.30.9-1.0-1.0-0.9
Time to tail flick, test, before self-admin0.90.92.60.9-0.91.0-1.0-0.60.6-0.60.50.21.10.40.10.9-1.1-0.11.3-0.91.61.31.6
Time to tail flick, test, after self-admin0.50.51.10.7-0.70.8-0.8-0.60.6-0.60.50.30.90.40.30.8-0.80.20.9-0.30.91.01.1
Delta time to tail flick, vehicle, before/after SA1.41.43.1-1.31.3-1.31.31.0-1.00.9-0.9-0.8-1.4-0.7-0.4-1.30.9-0.4-1.50.7-1.7-1.6-1.8
Delta time to tail flick, test, before/after SA0.30.21.1-0.10.1-0.10.1-0.10.1-0.10.20.4-0.30.30.5-0.10.30.5-0.50.9-1.1-0.7-1.0
Tibia length0.71.93.11.3-1.41.4-1.4-1.51.6-1.61.61.71.21.61.81.5-1.51.71.11.5-0.5-0.1-0.2
Ambulatory time before self-admin0.10.10.2-0.30.3-0.30.30.4-0.40.4-0.4-0.5-0.3-0.5-0.4-0.40.4-0.4-0.3-0.50.20.30.2
Ambulatory time after self-admin0.50.60.90.9-0.90.8-0.8-0.80.8-0.80.90.80.80.80.70.8-0.70.90.70.40.20.50.3
Bone: tissue strength1.51.52.5-1.21.2-1.11.11.4-1.41.4-1.4-1.4-1.0-1.5-1.5-1.41.1-1.6-1.0-1.30.40.20.2
Total heroin consumption1.72.02.61.6-1.61.6-1.6-1.61.6-1.61.61.41.51.51.51.6-1.51.41.40.80.40.20.5
Bone: trabecular number1.72.75.51.9-1.91.8-1.8-1.51.5-1.41.31.12.01.10.72.1-1.80.82.3-0.51.81.91.9
Bone: trabecular spacing2.32.97.0-1.81.8-1.71.71.1-1.11.1-1.0-0.7-2.1-0.7-0.1-2.01.8-0.2-2.51.4-2.6-2.6-2.6
Bone: trabecular thickness3.13.713.11.6-1.61.6-1.6-0.70.7-0.60.50.12.20.1-0.71.9-1.7-0.62.7-2.43.63.53.5
Bone: trabecular tissue density2.83.95.8-2.42.3-2.22.22.2-2.22.1-2.1-1.9-2.4-2.0-1.6-2.22.3-1.8-2.3-0.6-1.2-1.4-1.4
Water consumed over 24 hours0.40.51.9-0.30.3-0.30.30.6-0.60.6-0.7-0.80.0-0.8-1.00.10.2-1.00.5-1.41.21.11.1
Number of responses in last shaping day0.10.10.20.4-0.40.4-0.4-0.40.4-0.40.40.50.40.40.40.4-0.30.30.30.20.10.00.2