Hub : Genes

Zfp579

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_006228256.4 0.04 0.03 1.9e-04 0.03 0.03 0.04 0.03 3.0e-04 9.8e-05 2.4e-05 1.1e-04
2 Brain isoform ratio NM_001126276.1 0.03 0.02 3.6e-04 0.04 0.03 0.03 0.03 2.8e-04 4.2e-04 1.4e-03 6.0e-04
3 IL gene expression Zfp579 0.33 0.16 1.8e-05 0.14 0.13 0.14 0.14 2.8e-04 4.3e-04 3.6e-04 3.1e-04
4 BLA alternative TSS XM_006228256.4 0.08 0.05 3.4e-04 0.04 0.04 0.04 0.03 5.5e-03 2.5e-03 1.8e-03 6.2e-03
5 Brain alternative TSS XM_006228256.4 0.05 0.04 3.7e-07 0.05 0.07 0.04 0.06 9.5e-06 6.8e-07 6.2e-05 4.0e-06
6 Brain alternative TSS NM_001126276.1 0.05 0.03 9.2e-07 0.06 0.07 0.05 0.06 8.0e-06 9.4e-07 4.0e-05 3.8e-06
7 BLA alternative TSS NM_001126276.1 0.07 0.05 6.2e-04 0.03 0.04 0.04 0.03 7.3e-03 3.6e-03 3.6e-03 7.5e-03
8 NAcc alternative TSS NM_001126276.1 0.07 0.06 2.5e-07 0.06 0.06 0.07 0.06 2.0e-07 1.4e-07 2.4e-08 2.1e-07
9 Brain isoform ratio XM_006228256.4 0.03 0.02 3.9e-04 0.03 0.03 0.02 0.03 4.7e-04 4.5e-04 2.3e-03 6.1e-04
10 PL alternative TSS NM_001126276.1 0.06 0.04 2.7e-07 0.05 0.06 0.06 0.05 3.7e-06 6.6e-07 9.4e-07 2.2e-06
11 PL alternative TSS XM_006228256.4 0.06 0.04 1.9e-06 0.04 0.04 0.03 0.04 9.7e-05 1.1e-05 1.4e-04 7.3e-05
12 PL gene expression Zfp579 0.05 0.04 5.6e-04 0.03 0.03 0.02 0.03 3.1e-04 2.4e-04 1.6e-03 4.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.20.31.01.0-0.3-0.40.2-0.50.50.5-0.9-0.50.5-0.50.3
Area under the delay curve0.90.91.1-0.91.01.0-0.41.0-1.0-1.00.91.0-1.01.1-1.0
BMI with tail1.03.44.4-1.22.12.1-2.02.0-2.0-2.01.72.0-1.91.8-1.3
BMI without tail0.20.50.7-0.10.80.8-0.30.8-0.8-0.80.40.8-0.90.8-0.8
Body weight0.20.71.70.2-1.2-0.80.2-0.90.90.7-0.3-0.71.0-1.01.3
Weight adjusted by age1.51.74.62.2-1.0-1.01.8-1.11.11.2-1.9-1.20.9-0.90.1
Bone surface3.66.38.83.0-2.5-2.61.9-2.52.52.5-2.9-2.52.5-2.51.9
Bone volume2.95.08.12.9-2.1-2.21.3-2.22.22.2-2.7-2.22.3-2.31.8
Breakpoint value in progressive ratio session1.92.02.7-1.21.41.5-0.71.5-1.5-1.41.31.4-1.61.6-1.6
Number of licking bursts0.00.10.4-0.60.1-0.00.10.1-0.1-0.10.40.1-0.10.1-0.1
Context. condit. distance diff. score0.40.51.8-0.50.40.60.30.7-0.7-0.50.40.5-0.90.9-1.3
Locomotion velocity, session 10.70.73.61.20.60.60.80.3-0.30.1-0.9-0.1-0.70.8-1.9
Locomotion distance, session 12.22.85.92.4-1.4-1.42.2-1.51.51.8-2.2-1.81.2-1.1-0.1
Locomotion velocity, session 20.10.20.80.20.50.40.40.2-0.2-0.0-0.3-0.0-0.40.4-0.9
Locomotion distance, session 21.92.74.72.2-1.6-1.51.5-1.61.61.8-2.0-1.81.4-1.40.6
Locomotion velocity, session 30.10.10.2-0.30.30.4-0.30.2-0.2-0.20.20.2-0.30.3-0.3
Locomotion distance, session 30.20.20.70.7-0.2-0.20.8-0.30.30.5-0.7-0.50.2-0.1-0.3
Stereotopy head waving bouts, day 30.20.20.4-0.60.40.4-0.30.5-0.5-0.50.60.5-0.50.5-0.3
Stereotopy head waving duration, day 30.10.10.2-0.50.20.2-0.40.3-0.3-0.30.50.3-0.20.20.1
Locomotion velocity, session 70.10.10.30.5-0.2-0.00.1-0.20.20.3-0.5-0.30.1-0.1-0.3
Locomotion distance, session 70.10.10.50.30.00.30.10.1-0.10.1-0.2-0.1-0.20.3-0.7
Stereotopy head waving bouts, day 70.20.30.50.2-0.5-0.70.4-0.50.50.5-0.2-0.50.6-0.60.7
Stereotopy head waving duration, day 70.20.30.50.4-0.5-0.70.4-0.60.60.5-0.4-0.50.6-0.70.7
Locomotion velocity, session 80.10.21.00.60.20.30.20.1-0.10.0-0.4-0.1-0.40.4-1.0
Locomotion distance, session 80.20.20.90.6-0.4-0.10.9-0.10.10.3-0.5-0.3-0.20.2-1.0
Degree of sensitization distance0.00.00.00.0-0.10.0-0.00.1-0.1-0.00.10.0-0.10.1-0.2
Degree of sensitization stereotypy0.10.10.3-0.0-0.2-0.40.2-0.30.30.2-0.0-0.20.3-0.40.5
Conditioned locomotion0.10.10.60.5-0.00.00.70.0-0.00.1-0.3-0.1-0.20.3-0.8
Cocaine response after cond. corrected1.41.54.7-1.11.21.1-2.21.2-1.2-1.41.31.4-0.80.70.4
Cocaine response after cond. not corrected0.30.41.70.4-0.4-0.6-0.7-0.40.40.2-0.2-0.20.7-0.71.3
Cocaine response before conditioning6.88.210.22.8-3.0-3.13.2-3.03.03.1-2.9-3.12.7-2.71.5
Saline control response0.20.20.60.8-0.1-0.10.6-0.20.20.4-0.7-0.5-0.00.1-0.8
Bone: connectivity density0.00.00.10.40.20.1-0.20.1-0.1-0.1-0.20.1-0.10.1-0.1
Bone: cortical apparent density0.10.10.50.60.40.2-0.70.0-0.00.0-0.2-0.00.0-0.00.0
Bone: cortical area0.40.70.90.6-1.0-0.70.9-0.90.80.8-0.9-0.80.8-0.80.6
Bone: cortical porosity0.91.02.9-0.91.11.1-1.70.9-0.9-1.10.91.0-0.70.70.0
Bone: cortical porosity0.40.41.8-0.60.60.6-1.30.5-0.5-0.70.60.7-0.30.20.5
Bone: cortical thickness0.71.21.8-1.01.31.4-1.11.1-1.1-1.10.91.0-1.11.1-0.9
Bone: cortical thickness0.10.10.20.4-0.2-0.30.5-0.30.30.3-0.4-0.40.1-0.1-0.2
Bone: cortical tissue density0.10.10.50.70.30.2-0.7-0.00.00.0-0.3-0.10.1-0.10.1
Condit. Reinf. active minus inactive responses0.20.30.4-0.60.50.6-0.40.5-0.5-0.50.60.5-0.40.4-0.3
Condit. Reinf. active-inactive response ratio2.02.23.7-1.91.41.5-0.81.5-1.5-1.51.81.5-1.51.5-1.1
Condit. Reinf. active responses0.10.10.20.4-0.3-0.30.1-0.40.40.4-0.3-0.40.4-0.40.4
Condit. Reinf. inactive responses3.64.36.92.6-2.1-2.11.5-2.12.12.2-2.4-2.22.0-2.01.3
Incentive salience index mean0.00.10.10.2-0.3-0.10.3-0.20.20.3-0.2-0.30.2-0.20.1
Condit. Reinf. lever presses0.81.12.21.5-1.0-0.80.8-1.01.01.1-1.4-1.11.0-1.00.7
Condit. Reinf. active minus inactive responses4.35.37.01.7-2.6-2.62.2-2.52.52.5-2.0-2.52.4-2.31.6
Condit. Reinf. active-inactive response ratio7.17.58.92.3-3.0-2.91.8-2.92.92.8-2.5-2.83.0-3.02.6
Condit. Reinf. active responses3.04.16.11.3-2.4-2.32.5-2.22.22.3-1.7-2.31.9-1.80.9
Condit. Reinf. inactive responses0.20.31.1-0.7-0.2-0.21.00.1-0.10.10.5-0.1-0.30.4-0.9
Condit. Reinf. lever presses0.50.71.2-0.8-1.1-1.00.6-0.80.80.60.3-0.60.9-0.91.1
Condit. Reinf. lever reinforcers received3.55.07.51.4-2.6-2.52.7-2.42.42.5-1.9-2.52.1-2.01.0
Conditioned reinforcement - actives0.50.51.50.7-0.7-0.9-0.2-0.60.60.5-0.4-0.50.8-0.91.2
Conditioned reinforcement - inactives5.56.18.02.8-2.5-2.62.4-2.52.52.6-2.6-2.62.4-2.41.6
Conditioned locomotion0.81.02.11.0-1.0-1.1-0.0-1.01.00.8-0.8-0.81.2-1.21.4
Patch foraging indifference point 0 sec0.61.03.40.41.00.90.41.0-1.0-0.80.20.8-1.31.4-1.8
Patch foraging indifference point AUC0.40.50.6-0.70.80.6-0.60.7-0.7-0.70.80.7-0.70.7-0.5
Delay disc. indifference point, 0s delay0.40.41.51.10.40.40.90.3-0.3-0.1-0.60.1-0.60.6-1.2
Delay disc. indifference point, 16s delay1.11.14.3-2.10.60.6-1.60.7-0.7-0.91.60.9-0.40.30.5
Delay disc. indifference point, 2s delay0.50.61.0-0.31.00.8-0.60.8-0.8-0.80.60.7-0.90.9-0.9
Delay disc. indifference point, 24s delay0.70.71.7-1.30.70.6-1.00.8-0.8-0.91.20.9-0.60.6-0.1
Delay disc. indifference point, 4s delay0.00.00.1-0.3-0.1-0.1-0.1-0.10.10.10.1-0.10.2-0.20.3
Delay disc. indifference point, 8s delay0.10.10.4-0.20.30.40.30.4-0.4-0.30.20.3-0.50.5-0.6
Indifference point function ln k5.17.28.52.8-2.9-2.62.8-2.82.82.9-2.9-2.92.5-2.51.4
Indifference point function log k5.17.28.52.8-2.9-2.62.8-2.82.82.9-2.9-2.92.5-2.51.4
Patch foraging total patch changes 0 sec0.71.13.40.11.00.90.41.1-1.1-0.90.40.8-1.41.4-1.9
Patch foraging total patch changes 12 sec0.50.60.90.20.80.6-0.50.9-0.9-0.90.50.9-0.90.9-0.8
Patch foraging total patch changes 18 sec1.01.31.9-1.01.11.0-0.31.2-1.3-1.21.21.2-1.41.4-1.3
Patch foraging total patch changes 24 sec0.10.10.2-0.40.2-0.1-0.50.2-0.2-0.30.50.3-0.10.00.3
Patch foraging total patch changes 6 sec0.81.21.9-0.31.21.0-0.31.3-1.3-1.20.81.2-1.41.4-1.3
Patch foraging time to switch 0 sec2.84.312.5-2.71.71.7-3.51.8-1.8-2.22.62.2-1.21.00.8
Patch foraging water rate 0 sec0.61.04.91.1-0.8-0.92.2-0.70.70.9-0.9-1.00.3-0.2-0.8
Patch foraging water rate 12 sec1.82.811.21.4-1.7-1.63.3-1.51.51.7-1.6-1.81.0-0.9-0.5
Patch foraging water rate 18 sec0.81.03.10.9-1.0-0.91.8-1.01.01.2-0.9-1.20.7-0.6-0.3
Patch foraging water rate 24 sec0.60.82.00.5-1.0-1.01.4-0.90.91.1-0.6-1.10.7-0.6-0.1
Patch foraging water rate 6 sec4.97.29.91.4-3.1-3.02.2-3.03.02.9-2.0-2.92.9-2.92.3
Seeking ratio, delayed vs. immediate footshock0.50.62.51.30.30.41.00.3-0.3-0.1-0.70.1-0.70.8-1.6
Distance traveled before self-admin2.42.58.12.5-1.1-1.12.8-1.31.31.5-2.1-1.60.8-0.7-0.6
Distance traveled after self-admin0.80.94.41.10.20.32.10.1-0.10.2-1.1-0.2-0.50.6-1.6
Extensor digitorum longus weight0.20.81.30.5-1.1-0.80.5-0.90.90.8-0.7-0.81.0-1.01.1
Bone: elastic displacement0.20.20.60.20.50.60.00.4-0.4-0.3-0.10.3-0.50.5-0.8
Bone: elastic work0.60.71.91.0-0.8-0.71.4-0.80.80.9-1.1-0.90.6-0.5-0.1
Bone: endosteal estimation3.27.19.42.3-3.1-2.82.6-2.82.72.7-2.6-2.72.7-2.72.1
Bone: endosteal perimeter2.14.56.91.8-2.5-2.22.6-2.12.12.2-2.1-2.12.0-2.01.3
Epididymis fat weight1.12.510.3-3.21.01.3-1.11.3-1.3-1.42.41.4-1.11.0-0.3
Delta time in closed arm before/after self-admin0.10.10.30.60.50.2-0.50.3-0.3-0.3-0.10.3-0.20.2-0.1
Delta time in open arm before/after self-admin1.21.23.01.4-1.0-0.91.7-1.01.01.2-1.3-1.20.7-0.7-0.1
Diff in mean of infusions in LGA sessions0.30.41.80.70.40.40.90.3-0.3-0.1-0.30.1-0.60.7-1.3
Delay discount exponential model param0.70.70.90.9-0.9-0.90.3-0.90.90.9-0.8-0.90.9-0.90.9
Extinction: sum of active levers before priming0.60.62.80.50.50.61.10.5-0.5-0.2-0.30.2-0.80.9-1.7
Active lever presses in extinction session 60.60.62.4-1.50.20.3-1.20.4-0.4-0.51.10.6-0.10.00.7
Bone: final force1.62.63.41.1-1.8-1.60.9-1.81.81.7-1.4-1.71.8-1.81.7
Bone: final moment2.03.24.01.4-1.9-1.71.2-2.02.01.9-1.8-1.92.0-2.01.7
Food consumed during 24 hour testing period1.82.23.51.5-1.6-1.91.4-1.51.51.5-1.3-1.51.4-1.40.9
Glucose1.11.62.9-1.31.21.5-0.31.3-1.3-1.11.01.1-1.51.5-1.7
Heart weight2.23.14.92.2-1.8-1.91.6-1.81.81.8-2.1-1.81.6-1.61.0
Delay discount hyperbolic model param0.40.50.60.7-0.7-0.70.2-0.70.70.7-0.7-0.70.8-0.80.7
Intermittent access intake day 1-15 change1.31.21.90.4-1.4-1.11.2-1.31.31.3-0.8-1.31.1-1.10.6
Intermittent access intake escalation1.01.01.7-0.0-1.3-1.00.8-1.21.21.2-0.5-1.21.1-1.00.7
Intermittent access intake escalation 20.70.71.0-0.3-1.0-0.90.9-1.01.01.0-0.3-1.00.9-0.80.4
Intermitt. access day 1 inactive lever presses3.53.86.21.2-2.1-2.10.7-2.12.11.9-1.4-1.82.3-2.32.5
Intermitt. access day 15 inactive lever presses5.45.911.32.0-2.4-2.60.2-2.52.52.2-2.0-2.22.9-3.03.4
Intermitt. access escalation Index1.51.32.7-0.30.91.5-0.41.2-1.2-1.10.51.1-1.41.5-1.7
Intermittent access day 1 total infusions0.40.50.70.8-0.8-0.80.6-0.70.70.6-0.6-0.60.7-0.70.6
Intermittent access day 15 total infusions1.21.42.60.1-1.6-1.31.0-1.31.31.3-0.5-1.31.3-1.21.0
Intermittent access terminal intake (last 3 days)1.11.22.2-0.4-1.5-1.20.8-1.21.21.1-0.2-1.11.2-1.21.1
Intermittent access total infusions1.31.42.30.7-1.5-1.30.9-1.31.31.2-0.8-1.21.3-1.31.2
Intermittent access day 1 locomotion0.80.91.50.9-1.1-1.01.2-0.90.90.9-0.8-0.90.8-0.80.5
Intermittent access day 15 total locomotion0.70.71.6-0.7-1.2-0.81.3-0.90.91.00.0-1.00.8-0.70.3
Intermittent access total locomotion1.31.52.80.3-1.7-1.31.3-1.41.41.4-0.7-1.31.3-1.30.9
Intermittent access standard deviation1.31.411.3-3.4-0.30.0-0.80.0-0.0-0.22.10.20.1-0.10.8
Left kidney weight3.39.413.52.5-3.7-3.32.8-3.33.33.2-2.7-3.23.2-3.12.4
Right kidney weight2.46.710.01.9-3.2-2.92.2-2.82.82.7-2.0-2.62.7-2.72.3
Cocaine induced anxiety2.62.98.12.8-1.4-1.51.6-1.61.61.7-2.4-1.71.4-1.40.6
Post-drug Anxiety0.30.31.30.2-0.5-0.5-0.6-0.50.50.3-0.2-0.30.7-0.71.1
Baseline Anxiety1.92.18.4-2.90.80.9-2.10.9-0.9-1.22.21.2-0.50.50.7
Tail length1.23.66.41.5-2.3-2.02.5-1.91.92.0-1.8-1.91.7-1.70.9
Length with tail2.07.210.81.8-3.3-2.92.3-2.92.92.8-2.1-2.72.9-2.82.4
Length without tail0.81.83.10.4-1.6-1.40.6-1.51.51.3-0.7-1.31.6-1.61.8
Times rat made contact with spout0.00.00.1-0.20.20.1-0.30.2-0.2-0.30.20.3-0.20.10.1
Lifetime Intake0.60.71.10.6-1.0-0.90.6-0.90.90.9-0.6-0.80.9-0.90.7
Liver weight, left0.10.20.4-0.60.20.3-0.60.4-0.4-0.60.50.6-0.30.20.4
Liver weight, right0.10.20.5-0.70.00.1-0.50.3-0.3-0.50.70.5-0.10.10.4
Locomotor activity0.20.31.0-1.00.20.4-0.10.5-0.5-0.50.80.5-0.40.4-0.2
Locomotor testing distance0.00.10.3-0.5-0.3-0.20.2-0.10.1-0.00.40.00.2-0.20.4
Locomotor testing rearing0.50.71.21.0-1.0-1.01.1-0.80.80.8-0.9-0.80.7-0.70.5
Locomotion in novel chamber3.44.35.7-1.81.92.3-1.22.1-2.1-2.01.82.0-2.32.4-2.3
Locomotion in novel chamber post-restriction0.50.60.90.40.80.9-0.30.9-0.9-0.90.10.9-0.90.9-0.8
Fecal boli incidents, locomotor time 10.40.41.40.4-0.8-0.61.2-0.60.60.7-0.6-0.70.5-0.40.1
Change in fecal boli incidents, locomotor task3.83.64.8-1.22.22.1-1.42.1-2.1-2.01.51.9-2.12.1-1.9
Time >=10cm from walls, locomotor time 10.10.10.3-0.20.30.3-0.50.3-0.3-0.30.30.3-0.20.2-0.0
Bouts of movement, locomotor time 10.91.05.01.5-0.5-0.12.2-0.30.30.6-1.3-0.6-0.10.2-1.3
Total resting periods, locomotor time 10.40.42.00.20.00.41.40.2-0.20.0-0.3-0.0-0.50.6-1.3
Rest time, locomotor task time 12.02.23.50.7-1.9-1.61.4-1.61.61.6-1.1-1.61.6-1.61.3
Distance moved, locomotor task time 11.21.31.8-0.91.41.2-0.91.2-1.2-1.21.01.2-1.21.2-1.0
Vertical activity count, locomotor time 12.83.05.3-0.72.11.9-0.41.8-1.8-1.61.11.6-2.12.1-2.3
Time >=10cm from walls, locomotor time 21.11.22.3-1.21.11.1-1.51.1-1.1-1.11.21.1-0.90.9-0.4
Bouts of movement, locomotor time 20.00.00.1-0.2-0.10.10.20.0-0.0-0.00.10.0-0.10.1-0.1
Total resting periods, locomotor time 20.00.00.20.0-0.00.10.40.1-0.1-0.0-0.00.0-0.10.2-0.3
Rest time, locomotor task time 20.20.20.70.80.10.20.80.1-0.1-0.0-0.50.0-0.30.4-0.8
Distance moved, locomotor task time 20.10.10.2-0.40.30.3-0.40.3-0.3-0.30.30.3-0.20.2-0.1
Vertical activity count, locomotor time 20.40.40.9-0.80.60.70.30.6-0.6-0.50.60.5-0.80.8-0.9
Light reinforcement 10.40.74.62.10.40.40.20.1-0.10.2-1.3-0.2-0.40.4-1.2
Light reinforcement 21.41.93.6-1.21.61.9-1.41.4-1.3-1.21.11.2-1.41.4-1.3
Bone: marrow area3.37.29.62.3-3.1-2.82.7-2.82.82.7-2.7-2.72.7-2.72.2
Bone: maximum diameter0.91.72.70.7-1.6-1.31.5-1.31.31.3-1.2-1.31.3-1.31.1
Bone: maximum force2.54.35.61.4-2.4-2.11.5-2.22.22.1-1.8-2.12.3-2.32.1
Bone: maximum moment2.95.16.41.7-2.5-2.21.8-2.42.42.3-2.1-2.32.4-2.42.1
Mean time between licks in bursts0.71.01.6-0.31.21.1-0.61.1-1.1-1.00.50.9-1.21.2-1.3
Mean num. licks in bursts0.10.10.30.5-0.3-0.10.1-0.20.20.1-0.4-0.10.2-0.20.3
Cd content in liver1.11.34.11.5-1.1-1.02.0-0.90.91.1-1.3-1.10.6-0.5-0.3
Co content in liver0.40.42.31.50.0-0.10.1-0.40.40.5-1.2-0.60.3-0.3-0.1
Cu content in liver0.60.81.31.0-0.7-0.9-0.1-0.90.90.8-0.9-0.81.0-1.01.2
Fe content in liver0.10.10.70.80.20.1-0.1-0.10.10.1-0.6-0.10.00.0-0.2
K content in liver0.00.00.10.30.10.1-0.1-0.10.10.1-0.1-0.10.1-0.1-0.0
Mg content in liver0.30.30.4-0.60.50.5-0.60.5-0.5-0.50.60.5-0.40.4-0.2
Mn content in liver0.20.30.9-0.90.30.5-0.60.4-0.4-0.40.70.4-0.30.20.1
Na content in liver2.72.94.1-1.12.01.8-1.51.8-1.8-1.71.41.7-1.81.8-1.6
Rb content in liver0.20.30.70.6-0.4-0.7-0.3-0.50.50.4-0.4-0.40.6-0.60.8
Se content in liver2.43.04.9-2.21.61.8-1.21.7-1.7-1.82.01.8-1.71.7-1.2
Sr content in liver5.44.98.0-0.32.72.8-1.02.4-2.4-2.10.92.1-2.62.6-2.8
Zn content in liver0.20.20.9-0.80.10.1-1.00.2-0.2-0.30.70.30.0-0.10.7
Bone: minimum diameter3.46.47.92.5-2.8-2.72.6-2.62.62.6-2.7-2.62.5-2.41.7
Time in familiar zone, hab. session 12.82.66.71.6-1.8-1.72.6-1.51.51.8-1.7-1.81.1-1.1-0.1
Time in novel zone, hab. session 12.32.34.0-1.41.81.7-2.01.5-1.5-1.61.51.6-1.31.2-0.4
Total zone transitions, hab. session 10.81.14.02.0-0.4-0.61.2-0.80.81.1-1.7-1.10.5-0.5-0.5
Total locomotion distance, hab. session 10.30.41.31.1-0.2-0.21.0-0.40.40.6-1.0-0.60.1-0.0-0.8
Locomotion velocity, hab. session 10.20.30.91.0-0.2-0.20.7-0.30.30.5-0.8-0.50.1-0.1-0.6
Time in familiar zone, hab. session 23.03.14.60.7-2.1-2.21.5-1.91.91.7-1.1-1.71.9-1.91.9
Time in novel zone, hab. session 22.02.03.0-0.81.71.7-1.51.5-1.5-1.41.01.4-1.41.4-1.1
Total zone transitions, hab. session 22.02.65.62.4-1.4-1.52.2-1.41.41.6-2.1-1.61.1-1.10.0
Total locomotion distance, hab. session 20.30.31.31.10.00.00.9-0.00.00.2-0.8-0.2-0.30.3-1.0
Locomotion velocity, hab. session 20.30.41.41.10.20.20.90.1-0.10.1-0.8-0.1-0.40.4-1.2
Novel to familiar place preference ratio0.00.00.0-0.1-0.1-0.10.2-0.10.00.00.0-0.00.1-0.10.2
Novelty place preference0.10.10.20.1-0.3-0.30.4-0.30.30.3-0.2-0.30.3-0.30.2
Time in novel zone, NPP test0.10.10.20.1-0.4-0.40.5-0.30.30.3-0.2-0.30.3-0.30.2
Total zone transitions, NPP test0.20.31.60.6-0.4-0.41.3-0.30.30.5-0.5-0.50.1-0.1-0.6
Total locomotion distance, NPP test0.20.30.70.5-0.6-0.60.9-0.50.50.6-0.4-0.50.4-0.40.0
Locomotion velocity, NPP test0.30.41.00.7-0.6-0.61.0-0.50.50.6-0.6-0.60.4-0.3-0.1
Intraocular pressure0.00.10.40.40.20.1-0.6-0.10.10.1-0.3-0.10.1-0.10.2
Delta distance traveled before/after self-admin1.21.31.5-1.11.21.2-0.51.2-1.2-1.10.91.1-1.21.2-1.1
Delta ambulatory time before/after self-admin0.91.01.4-0.71.11.1-0.31.1-1.1-1.00.71.0-1.21.2-1.1
Parametrial fat weight5.210.211.4-3.33.33.3-2.93.3-3.3-3.43.33.4-3.23.1-2.2
Pavlov. Cond. lever latency0.10.10.6-0.20.20.2-0.70.1-0.1-0.10.20.1-0.10.10.0
Pavlov. Cond. magazine entry latency0.30.41.9-0.60.50.5-1.40.5-0.5-0.70.70.7-0.20.10.6
Pavlov. Cond. change in total contacts0.20.20.3-0.10.60.40.20.5-0.5-0.40.20.4-0.50.5-0.5
Pavlov. Cond. index score0.20.20.4-0.20.60.5-0.30.6-0.6-0.60.30.6-0.60.5-0.4
Pavlov. Cond. latency score0.20.20.3-0.20.50.5-0.00.5-0.5-0.50.30.5-0.50.5-0.4
Pavlov. Cond. lever contacts0.10.20.60.4-0.4-0.40.8-0.30.30.2-0.3-0.20.3-0.30.4
Pavlov. Cond. magazine entry number0.10.20.20.2-0.5-0.50.5-0.50.50.5-0.4-0.50.4-0.40.2
Pavlov. Cond. intertrial magazine entries0.30.42.20.40.40.11.20.2-0.20.0-0.2-0.0-0.60.7-1.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.3-0.20.60.5-0.30.5-0.5-0.60.40.6-0.50.5-0.3
Pavlov. Cond. response bias0.10.21.00.2-0.2-0.3-0.5-0.20.20.0-0.0-0.00.4-0.51.0
Pavlov. Cond. lever latency0.81.03.01.7-0.8-1.00.9-0.90.90.9-1.4-0.90.8-0.90.5
Pavlov. Cond. magazine entry latency1.11.23.2-1.81.01.1-0.91.0-1.0-1.11.51.1-0.90.9-0.4
Pavlov. Cond. change in total contacts0.10.10.3-0.2-0.4-0.20.3-0.50.50.5-0.2-0.50.4-0.30.1
Pavlov. Cond. index score0.30.41.8-1.40.40.5-0.80.3-0.3-0.41.00.4-0.20.20.2
Pavlov. Cond. latency score0.60.72.8-1.70.60.8-1.10.6-0.6-0.71.30.7-0.50.50.0
Pavlov. Cond. lever contacts0.20.31.8-1.30.10.3-0.60.1-0.1-0.20.90.2-0.00.10.3
Pavlov. Cond. magazine entry number0.50.62.31.5-0.6-0.80.7-0.60.60.7-1.2-0.70.5-0.50.2
Pavlov. Cond. intertrial magazine entries3.64.75.82.4-2.3-2.41.7-2.22.22.2-2.3-2.22.2-2.21.6
Pavlov. Cond. lever-magazine prob. diff.0.20.31.5-1.20.30.4-0.70.2-0.2-0.30.80.3-0.10.10.2
Pavlov. Cond. response bias0.20.20.7-0.6-0.5-0.3-0.2-0.50.50.40.2-0.40.6-0.60.8
Time in closed arm before self-admin0.70.81.30.3-1.0-0.90.2-1.01.00.9-0.6-0.91.1-1.11.1
Time in closed arm after self-admin0.20.21.1-0.4-0.0-0.3-1.0-0.20.2-0.00.20.00.4-0.51.0
Time in open arm before self-admin0.91.01.4-0.11.21.0-0.81.2-1.1-1.10.71.1-1.11.1-0.9
Time in open arm after self-admin0.30.31.50.60.40.50.60.4-0.4-0.3-0.10.3-0.70.7-1.2
Bone: periosteal estimation2.14.45.81.8-2.4-2.12.2-2.22.22.1-2.2-2.12.1-2.11.6
Bone: periosteal perimeter1.82.93.91.4-2.0-1.72.0-1.81.81.8-1.8-1.81.7-1.61.1
Bone: post-yield work2.43.34.70.8-2.2-2.11.2-2.01.91.8-1.1-1.82.1-2.12.1
Progressive ratio test 1 active lever presses1.81.85.62.4-1.1-1.21.6-1.21.21.3-1.8-1.31.0-0.90.2
Progressive ratio test 1 breakpoint1.71.85.22.3-1.1-1.21.6-1.21.21.3-1.8-1.31.0-1.00.3
Progressive ratio test 1 inactive lever presses4.85.36.72.6-2.3-2.42.1-2.42.42.4-2.4-2.32.3-2.31.7
Progressive ratio test 2 active lever presses1.01.12.1-0.1-1.4-1.20.8-1.21.21.1-0.4-1.11.1-1.10.9
Progressive ratio test 2 breakpoint1.31.52.70.1-1.6-1.40.8-1.41.41.3-0.5-1.31.4-1.41.2
Progressive ratio test 2 inactive lever presses3.23.74.71.4-2.2-2.11.6-2.12.12.0-1.6-2.02.1-2.01.6
Incentive Sensitization - Responses3.73.86.20.4-2.5-2.10.9-2.22.22.0-1.0-2.02.3-2.32.2
Incentive Sensitization - Breakpoint2.62.64.50.0-2.1-1.80.5-1.81.81.7-0.6-1.61.9-1.92.0
Sum of active levers in priming session hrs 5-60.30.21.30.20.30.40.70.3-0.3-0.1-0.10.1-0.60.6-1.1
Progressive ratio0.30.41.20.00.70.60.50.6-0.6-0.50.10.4-0.80.8-1.1
Food seeking constrained by brief footshock2.22.79.02.80.60.42.90.4-0.40.2-1.9-0.2-1.11.2-3.0
Seeking ratio, punishment vs. effort0.50.62.21.5-0.6-0.51.3-0.50.50.7-1.1-0.70.2-0.2-0.5
Retroperitoneal fat weight6.220.427.6-5.34.44.7-3.44.6-4.6-4.65.14.6-4.54.5-3.4
Reaction time number correct0.30.51.1-1.00.40.50.60.6-0.6-0.50.60.5-0.80.8-1.0
Reaction time mean minus median0.00.00.2-0.4-0.20.10.0-0.10.10.10.1-0.10.1-0.10.1
Reaction time mean minus median AUC0.00.00.3-0.5-0.10.2-0.30.1-0.1-0.10.30.1-0.00.00.2
Reaction time num false alarms0.00.00.30.40.10.1-0.5-0.10.10.1-0.2-0.10.1-0.10.2
Reaction time num false alarms AUC0.20.30.60.40.70.7-0.50.5-0.4-0.3-0.00.3-0.60.6-0.8
Reaction time trials correct on left0.30.51.1-1.00.40.50.60.6-0.6-0.50.60.5-0.80.8-1.0
Reaction time trials on left0.30.41.0-1.00.40.50.60.6-0.6-0.50.60.5-0.70.8-1.0
Reaction time mean0.81.23.00.2-1.1-1.0-0.3-1.11.11.0-0.4-1.01.4-1.41.7
Reaction time mean AUC0.40.62.1-0.2-0.7-0.6-0.7-0.70.70.50.1-0.51.0-1.01.5
Median of all reaction times0.81.02.80.3-0.9-1.0-0.3-1.11.10.9-0.3-0.91.3-1.31.7
Reaction time omissions0.10.10.3-0.00.50.6-0.20.3-0.3-0.2-0.20.2-0.30.3-0.3
Reaction time false alarm rate0.10.10.50.60.40.3-0.70.1-0.1-0.1-0.20.0-0.10.1-0.2
Reaction time premature initiation rate0.10.21.0-1.0-0.4-0.20.3-0.10.0-0.00.80.00.1-0.10.2
Reaction time premature initiations0.30.42.7-1.6-0.10.10.30.3-0.3-0.41.20.4-0.30.3-0.2
Std. dev. reaction times0.40.61.4-0.1-1.0-0.70.1-0.80.80.7-0.2-0.71.0-1.01.2
Reaction time trials completed0.30.41.0-1.00.40.50.60.6-0.6-0.50.60.5-0.70.8-1.0
Reaction time trials AUC0.30.41.1-1.10.20.40.70.5-0.5-0.40.60.4-0.70.7-0.9
Run reversals in cocaine runway, females0.60.51.20.9-0.6-0.8-0.2-0.70.70.6-0.7-0.60.8-0.91.1
Run reversals in cocaine runway, males0.10.10.20.2-0.2-0.3-0.1-0.30.30.2-0.2-0.20.3-0.30.4
Latency to leave start box in cocaine runway0.30.40.50.1-0.7-0.70.4-0.70.70.7-0.3-0.70.7-0.70.5
Latency to leave start box in cocaine runway, F0.10.10.2-0.2-0.3-0.30.4-0.30.30.4-0.1-0.40.3-0.30.1
Latency to leave start box in cocaine runway, M0.60.61.10.1-1.0-0.90.1-0.80.80.8-0.2-0.80.9-0.90.9
Std. dev. time between licks in bursts0.30.31.41.00.30.20.50.0-0.00.2-0.8-0.2-0.30.4-1.2
Total sessions with >9 infusions1.41.62.51.0-1.6-1.20.9-1.41.41.3-1.1-1.31.3-1.31.1
Short access day 1 total inactive lever presses0.80.93.3-0.7-1.0-0.9-0.4-0.90.90.60.2-0.61.2-1.21.8
Short access day 10 total inactive lever presses0.60.71.60.6-0.9-0.80.1-0.90.90.7-0.7-0.71.0-1.11.3
Short access day 1 total infusions0.00.00.20.1-0.2-0.10.4-0.20.20.2-0.1-0.20.1-0.1-0.1
Short access day 10 total infusions0.10.10.7-0.9-0.1-0.10.10.0-0.0-0.10.70.1-0.00.00.1
Short access total infusions0.20.30.6-0.10.50.5-0.00.6-0.6-0.50.40.5-0.60.7-0.8
Short access day 1 locomotion0.80.92.41.5-0.9-0.90.8-0.90.90.9-1.1-0.80.9-0.90.6
Short access day 10 total locomotion0.60.72.50.6-0.9-0.71.6-0.80.80.9-0.7-0.90.5-0.4-0.2
Short access total locomotion0.30.31.20.9-0.00.11.10.1-0.10.1-0.6-0.1-0.30.4-1.0
One hour access (0.3 mA shock)3.03.55.60.6-2.4-2.11.2-2.12.12.0-1.1-2.02.1-2.11.9
Compulsive drug intake0.70.81.30.2-1.2-0.70.8-1.01.01.0-0.6-1.00.9-0.90.6
One hour access (shock baseline)1.11.33.10.7-1.3-1.4-0.1-1.21.21.0-0.6-0.91.4-1.41.8
Social response proportion1.11.22.41.0-1.0-1.2-0.2-1.11.11.0-0.9-1.01.3-1.31.6
Social responses3.64.65.62.4-2.1-2.21.1-2.22.22.1-2.2-2.12.3-2.32.1
Social time4.35.714.33.8-2.0-2.12.9-2.12.12.3-3.3-2.41.7-1.70.4
Soleus weight0.00.10.30.2-0.4-0.00.6-0.20.10.2-0.3-0.20.1-0.0-0.1
Bone: stiffness2.33.64.81.2-2.1-2.10.9-2.02.01.9-1.5-1.92.2-2.22.2
Tibialis anterior weight0.93.26.0-2.41.31.7-0.71.8-1.9-1.92.22.0-1.81.8-1.2
Time to tail flick, vehicle, before self-admin0.60.70.90.4-1.0-0.90.8-0.90.90.9-0.6-0.90.8-0.80.5
Time to tail flick, vehicle, after self-admin0.90.91.7-1.1-1.1-0.90.2-1.01.00.90.2-0.91.1-1.11.3
Time to tail flick, test, before self-admin1.21.24.62.1-0.3-0.12.0-0.20.20.5-1.6-0.6-0.30.4-1.6
Time to tail flick, test, after self-admin0.20.21.21.1-0.1-0.3-0.6-0.20.20.1-0.5-0.10.3-0.40.5
Delta time to tail flick, vehicle, before/after SA0.60.63.5-1.90.10.2-0.90.2-0.2-0.41.30.4-0.00.00.5
Delta time to tail flick, test, before/after SA0.50.42.1-0.1-0.1-0.4-1.4-0.20.2-0.00.30.00.6-0.71.4
Tibia length3.710.413.53.1-3.6-3.72.6-3.43.33.2-2.9-3.23.3-3.42.8
Ambulatory time before self-admin2.02.05.22.3-1.2-1.02.2-1.21.21.4-1.9-1.40.8-0.7-0.3
Ambulatory time after self-admin1.51.66.82.3-0.4-0.42.6-0.50.50.9-1.9-0.90.1-0.0-1.2
Bone: tissue strength0.40.41.90.4-0.00.01.30.1-0.10.1-0.2-0.1-0.50.5-1.4
Total heroin consumption1.01.11.8-0.71.21.2-0.51.1-1.1-1.00.91.0-1.21.3-1.3
Bone: trabecular number0.10.10.40.40.40.3-0.00.3-0.3-0.2-0.10.2-0.40.4-0.6
Bone: trabecular spacing0.10.10.2-0.30.20.4-0.30.3-0.4-0.40.30.4-0.30.3-0.1
Bone: trabecular thickness0.10.10.30.6-0.0-0.1-0.2-0.10.10.1-0.4-0.10.2-0.20.2
Bone: trabecular tissue density1.11.53.6-1.71.11.1-1.91.1-1.1-1.31.61.3-0.70.70.3
Water consumed over 24 hours0.91.11.81.3-1.0-1.11.3-1.01.01.2-1.2-1.20.8-0.80.0
Number of responses in last shaping day0.30.40.90.2-0.6-0.80.1-0.60.60.5-0.1-0.50.7-0.81.0