Hub : Genes

Zfp579

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Zfp579 0.04 0.03 1.2e-03 0.01 0.01 0.02 0.01 2.4e-02 1.5e-02 1.4e-03 1.1e-02
2 Brain alternative TSS XM_006228256.5 0.04 0.03 1.5e-05 0.03 0.05 0.05 0.05 3.7e-04 9.9e-06 1.8e-05 1.7e-05
3 Brain alternative TSS NM_001126276.1 0.04 0.03 1.7e-05 0.03 0.05 0.05 0.05 3.4e-04 1.1e-05 2.5e-05 1.9e-05
4 BLA alternative TSS NM_001126276.1 0.09 0.06 3.8e-04 0.01 0.02 0.01 0.01 7.9e-02 4.3e-02 1.0e-01 9.7e-02
5 BLA alternative TSS XM_006228256.5 0.09 0.06 3.3e-04 0.01 0.02 0.01 0.01 7.6e-02 4.2e-02 8.9e-02 8.5e-02
6 Brain isoform ratio NM_001126276.1 0.03 0.02 6.7e-04 0.02 0.03 0.02 0.02 7.7e-03 1.6e-03 9.5e-03 8.4e-03
7 Brain isoform ratio XM_006228256.5 0.03 0.02 5.4e-04 0.02 0.03 0.02 0.02 4.4e-03 9.7e-04 5.6e-03 5.6e-03
8 IC alternative TSS XM_006228256.5 0.1 0.07 3.2e-03 0.03 0.04 0.02 0.04 1.4e-02 7.3e-03 5.0e-02 9.0e-03
9 IC alternative TSS NM_001126276.1 0.1 0.07 3.4e-03 0.03 0.04 0.03 0.04 1.4e-02 7.4e-03 1.5e-02 9.1e-03
10 NAcc alternative TSS NM_001126276.1 0.06 0.04 1.9e-09 0.05 0.06 0.05 0.06 2.0e-08 5.8e-09 4.9e-08 7.4e-09
11 NAcc alternative TSS XM_006228256.5 0.06 0.04 1.9e-09 0.06 0.06 0.05 0.06 3.3e-09 6.5e-09 1.9e-08 3.8e-09
12 IL gene expression Zfp579 0.35 0.16 1.9e-05 0.02 0.1 0.11 0.1 1.3e-01 2.8e-03 1.5e-03 2.7e-03
13 PL alternative TSS XM_006228256.5 0.04 0.03 4.9e-04 0.03 0.03 0.03 0.03 2.5e-04 6.7e-04 3.5e-04 5.0e-04
14 PL alternative TSS NM_001126276.1 0.04 0.03 5.7e-04 0.03 0.03 0.03 0.03 4.3e-04 8.0e-04 3.8e-04 7.5e-04
15 PL gene expression Zfp579 0.05 0.04 3.6e-04 0.01 0.02 0.03 0.02 9.6e-03 1.4e-03 8.5e-04 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.10.20.3-0.2-0.50.50.5-0.50.5-0.5-0.50.50.4-0.60.3-0.40.40.4
Area under the delay curve0.50.61.2-0.80.7-0.7-0.70.7-0.70.70.7-0.7-0.70.8-0.81.1-0.7-0.9
BMI with tail0.51.62.0-0.61.4-1.4-1.41.4-1.41.41.4-1.4-1.21.4-1.21.3-1.1-0.9
BMI without tail0.10.20.40.6-0.40.40.3-0.30.3-0.3-0.30.30.6-0.40.5-0.00.30.4
Body weight1.04.47.32.7-2.22.12.0-2.02.0-2.0-2.02.02.3-1.92.3-1.82.21.9
Weight adjusted by age0.40.61.00.5-0.80.81.0-1.01.0-1.0-0.90.90.5-0.80.5-0.60.30.1
Bone surface3.05.56.02.0-2.42.42.4-2.42.4-2.4-2.42.42.4-2.42.3-2.42.22.0
Bone volume2.64.75.41.7-2.32.32.2-2.22.2-2.2-2.32.32.2-2.32.1-2.22.11.9
Breakpoint value in progressive ratio session0.40.51.0-0.70.7-0.7-0.70.7-0.70.70.7-0.7-0.70.8-1.00.8-0.4-0.6
Number of licking bursts0.10.10.4-0.70.3-0.3-0.40.4-0.40.40.4-0.4-0.30.4-0.20.3-0.2-0.1
Context. condit. distance diff. score0.30.31.10.20.6-0.5-0.30.3-0.40.40.5-0.5-0.80.7-0.70.3-0.7-1.0
Locomotion velocity, session 10.30.31.8-0.70.2-0.20.3-0.30.2-0.3-0.00.0-0.8-0.0-0.80.0-1.1-1.4
Locomotion distance, session 11.92.43.51.3-1.61.61.9-1.91.8-1.9-1.71.71.0-1.61.1-1.91.20.5
Locomotion velocity, session 20.20.21.6-1.30.4-0.3-0.10.1-0.20.10.2-0.2-0.60.1-0.60.2-0.6-0.7
Locomotion distance, session 21.62.23.20.7-1.61.61.8-1.81.8-1.8-1.71.71.3-1.71.2-1.21.10.6
Locomotion velocity, session 30.00.00.1-0.10.2-0.2-0.10.1-0.10.10.1-0.1-0.30.1-0.0-0.30.30.0
Locomotion distance, session 30.20.20.50.3-0.40.40.5-0.50.5-0.5-0.40.40.1-0.40.3-0.70.50.1
Stereotopy head waving bouts, day 30.10.10.20.40.4-0.4-0.40.4-0.40.40.4-0.4-0.30.5-0.2-0.2-0.30.0
Stereotopy head waving duration, day 30.10.10.30.50.4-0.4-0.40.4-0.40.40.4-0.4-0.30.4-0.1-0.2-0.20.1
Locomotion velocity, session 70.10.10.50.2-0.20.20.3-0.30.3-0.3-0.30.3-0.0-0.30.1-0.70.20.1
Locomotion distance, session 70.10.10.6-0.7-0.10.10.2-0.20.2-0.2-0.10.1-0.2-0.1-0.30.1-0.6-0.6
Stereotopy head waving bouts, day 70.30.31.01.0-0.30.30.3-0.20.3-0.2-0.30.30.5-0.30.6-0.90.80.8
Stereotopy head waving duration, day 70.30.31.11.1-0.40.40.3-0.30.3-0.3-0.30.30.5-0.30.6-0.90.80.8
Locomotion velocity, session 80.10.10.2-0.40.1-0.10.1-0.10.1-0.10.0-0.0-0.50.0-0.5-0.4-0.2-0.5
Locomotion distance, session 80.10.10.50.3-0.20.20.5-0.50.4-0.5-0.30.3-0.2-0.1-0.1-0.2-0.2-0.7
Degree of sensitization distance0.00.00.1-0.1-0.00.00.1-0.10.1-0.1-0.00.0-0.00.0-0.10.1-0.3-0.2
Degree of sensitization stereotypy0.10.10.60.8-0.10.1-0.00.0-0.00.0-0.00.00.2-0.00.3-0.50.50.6
Conditioned locomotion0.10.10.3-0.6-0.00.00.2-0.20.2-0.2-0.10.1-0.2-0.0-0.2-0.4-0.3-0.3
Cocaine response after cond. corrected1.11.32.2-1.21.2-1.2-1.51.5-1.41.41.2-1.2-0.71.0-0.91.3-0.5-0.1
Cocaine response after cond. not corrected0.20.20.80.1-0.40.40.1-0.10.2-0.2-0.30.30.7-0.50.6-0.10.70.9
Cocaine response before conditioning6.57.89.42.8-2.92.93.1-3.13.0-3.0-2.92.92.6-2.82.8-2.72.21.8
Saline control response0.10.11.4-0.30.00.00.3-0.30.2-0.3-0.10.1-0.4-0.10.0-1.20.10.1
Bone: connectivity density0.00.00.2-0.50.2-0.1-0.20.2-0.20.20.1-0.1-0.10.1-0.10.1-0.10.0
Bone: cortical apparent density0.20.31.8-1.4-0.30.30.4-0.40.4-0.4-0.40.40.0-0.5-0.20.5-0.6-0.6
Bone: cortical area0.81.33.11.8-1.11.11.1-1.11.1-1.1-1.01.01.0-0.91.2-1.31.10.9
Bone: cortical porosity0.40.41.0-1.00.6-0.6-0.80.8-0.70.70.6-0.6-0.40.6-0.4-0.20.20.5
Bone: cortical porosity0.20.20.9-0.30.2-0.2-0.40.4-0.40.40.2-0.20.10.20.0-0.60.80.9
Bone: cortical thickness0.30.40.7-0.70.7-0.7-0.60.6-0.60.60.7-0.7-0.80.7-0.70.2-0.6-0.4
Bone: cortical thickness0.20.21.0-1.0-0.30.30.4-0.40.4-0.4-0.40.40.2-0.40.00.3-0.5-0.3
Bone: cortical tissue density0.20.31.8-1.3-0.30.30.4-0.40.4-0.4-0.40.40.0-0.5-0.20.5-0.6-0.6
Condit. Reinf. active minus inactive responses0.20.20.20.10.5-0.5-0.50.5-0.50.50.5-0.5-0.40.5-0.3-0.20.50.0
Condit. Reinf. active-inactive response ratio1.71.82.5-0.61.5-1.5-1.51.5-1.51.51.5-1.5-1.41.6-1.31.2-0.6-1.0
Condit. Reinf. active responses0.30.31.20.7-0.40.40.4-0.40.4-0.4-0.40.40.4-0.40.4-1.11.00.8
Condit. Reinf. inactive responses3.54.26.01.7-2.12.12.2-2.22.2-2.2-2.22.21.9-2.21.8-2.41.71.7
Incentive salience index mean0.10.10.60.6-0.30.30.3-0.30.3-0.3-0.30.30.2-0.30.2-0.40.80.2
Condit. Reinf. lever presses0.71.01.40.5-1.11.11.1-1.11.1-1.1-1.21.21.0-1.20.8-0.60.90.4
Condit. Reinf. active minus inactive responses3.24.25.01.5-2.22.22.2-2.22.2-2.2-2.22.22.1-2.12.0-1.91.61.6
Condit. Reinf. active-inactive response ratio5.46.38.01.8-2.72.72.6-2.62.6-2.6-2.72.72.8-2.72.5-2.12.12.2
Condit. Reinf. active responses2.33.14.21.3-1.91.92.0-2.02.0-2.0-1.91.91.6-1.71.7-1.91.41.1
Condit. Reinf. inactive responses0.10.10.20.40.2-0.2-0.00.0-0.10.10.2-0.2-0.50.5-0.1-0.40.1-0.4
Condit. Reinf. lever presses0.71.03.41.8-0.80.70.6-0.60.6-0.6-0.60.61.0-0.51.2-1.11.51.3
Condit. Reinf. lever reinforcers received3.14.35.51.7-2.22.22.3-2.32.3-2.3-2.22.21.9-2.02.0-2.21.61.3
Conditioned reinforcement - actives0.30.41.71.3-0.60.60.6-0.60.6-0.6-0.70.70.7-0.70.8-0.30.40.3
Conditioned reinforcement - inactives2.23.24.21.5-2.02.02.0-2.02.0-2.0-2.12.11.8-2.01.5-1.01.00.8
Conditioned locomotion0.10.10.30.5-0.40.40.4-0.40.4-0.4-0.40.40.5-0.50.30.10.10.0
Patch foraging indifference point 0 sec0.30.61.4-0.40.9-0.9-0.60.6-0.70.70.8-0.8-1.20.8-1.00.2-0.7-1.0
Patch foraging indifference point AUC0.40.50.7-0.30.8-0.8-0.90.9-0.80.80.8-0.8-0.70.7-0.60.5-0.6-0.3
Delay disc. indifference point, 0s delay0.10.20.7-0.70.1-0.10.1-0.10.1-0.10.1-0.1-0.50.2-0.40.4-0.7-0.9
Delay disc. indifference point, 16s delay0.50.61.1-0.60.8-0.8-1.01.0-1.01.00.9-0.9-0.40.7-0.60.7-0.1-0.1
Delay disc. indifference point, 2s delay0.80.82.4-1.60.8-0.8-0.70.7-0.70.70.7-0.7-0.80.7-0.81.3-1.1-1.1
Delay disc. indifference point, 24s delay0.70.81.2-1.10.8-0.8-0.90.9-0.90.90.9-0.9-0.60.8-1.01.1-0.4-0.6
Delay disc. indifference point, 4s delay0.00.00.10.3-0.20.20.2-0.20.2-0.2-0.20.20.3-0.20.30.00.30.2
Delay disc. indifference point, 8s delay0.20.20.5-0.30.4-0.4-0.30.3-0.40.30.4-0.4-0.50.5-0.50.7-0.5-0.7
Indifference point function ln k3.76.58.61.1-2.82.82.9-2.92.9-2.9-2.82.82.5-2.82.3-2.31.91.6
Indifference point function log k3.76.58.61.1-2.82.82.9-2.92.9-2.9-2.82.82.5-2.82.3-2.31.91.6
Patch foraging total patch changes 0 sec0.40.71.4-0.60.9-0.9-0.60.6-0.70.70.8-0.8-1.20.9-1.00.3-0.8-1.1
Patch foraging total patch changes 12 sec0.30.30.50.70.6-0.6-0.60.6-0.60.60.6-0.6-0.70.7-0.50.2-0.2-0.5
Patch foraging total patch changes 18 sec0.60.91.50.11.1-1.1-1.01.0-1.01.01.1-1.1-1.21.2-1.10.3-0.4-0.7
Patch foraging total patch changes 24 sec0.00.10.40.6-0.10.0-0.10.1-0.10.10.0-0.00.20.00.3-0.00.50.3
Patch foraging total patch changes 6 sec0.81.31.80.31.3-1.3-1.21.2-1.21.21.3-1.3-1.31.3-1.10.6-0.8-1.0
Patch foraging time to switch 0 sec1.32.75.00.71.7-1.8-2.22.2-2.22.21.9-1.9-0.91.8-0.91.50.10.1
Patch foraging water rate 0 sec0.20.51.1-0.1-0.70.81.0-1.11.0-1.0-0.80.80.3-0.70.3-0.5-0.3-0.4
Patch foraging water rate 12 sec0.91.93.50.6-1.51.51.8-1.91.8-1.8-1.61.60.9-1.31.1-1.30.50.1
Patch foraging water rate 18 sec0.60.91.6-0.1-1.01.01.3-1.31.2-1.2-1.11.10.6-0.90.7-1.00.10.2
Patch foraging water rate 24 sec0.60.81.30.0-1.01.01.1-1.11.1-1.1-1.01.00.7-1.00.8-1.10.40.4
Patch foraging water rate 6 sec5.58.09.02.3-2.92.92.9-2.92.9-2.9-2.92.92.9-2.93.0-2.92.72.6
Seeking ratio, delayed vs. immediate footshock0.10.21.10.00.1-0.10.3-0.30.2-0.2-0.00.0-0.60.2-0.50.2-0.8-1.0
Distance traveled before self-admin1.11.42.9-0.3-1.21.31.7-1.71.6-1.6-1.41.40.5-1.20.5-1.10.2-0.2
Distance traveled after self-admin0.91.13.3-1.80.8-0.7-0.40.4-0.40.40.7-0.7-1.30.9-1.51.0-1.4-1.6
Extensor digitorum longus weight0.20.81.51.2-0.90.90.8-0.80.8-0.8-0.80.81.1-0.81.0-0.60.80.8
Bone: elastic displacement0.20.20.60.10.6-0.6-0.50.5-0.50.50.5-0.5-0.80.6-0.5-0.6-0.0-0.1
Bone: elastic work0.50.71.71.3-0.70.80.9-0.90.8-0.9-0.80.80.5-0.70.8-1.00.60.4
Bone: endosteal estimation2.75.910.53.2-2.52.52.4-2.42.4-2.4-2.42.42.6-2.32.5-1.92.01.7
Bone: endosteal perimeter1.53.37.32.7-1.91.81.9-1.91.8-1.8-1.81.81.8-1.61.9-1.51.51.1
Epididymis fat weight0.10.55.12.3-0.00.0-0.30.3-0.30.30.1-0.10.50.10.40.10.70.7
Delta time in closed arm before/after self-admin0.10.10.2-0.10.1-0.1-0.20.2-0.10.10.1-0.1-0.10.0-0.20.5-0.5-0.3
Delta time in open arm before/after self-admin1.41.42.10.6-1.21.21.3-1.31.3-1.3-1.31.31.0-1.20.9-1.40.90.9
Diff in mean of infusions in LGA sessions0.00.00.30.10.00.00.2-0.20.2-0.2-0.10.1-0.30.1-0.20.2-0.4-0.5
Delay discount exponential model param0.40.41.00.7-0.60.60.6-0.60.6-0.6-0.60.60.6-0.70.7-1.00.60.8
Extinction: sum of active levers before priming0.10.10.4-0.50.3-0.3-0.20.2-0.20.20.3-0.3-0.50.4-0.60.4-0.4-0.6
Active lever presses in extinction session 60.10.10.20.10.1-0.1-0.40.4-0.40.40.2-0.20.30.10.20.50.10.4
Bone: final force2.23.54.21.9-2.02.02.0-2.02.0-2.0-2.02.02.0-2.11.9-1.41.21.2
Bone: final moment2.74.45.22.1-2.32.32.3-2.32.3-2.3-2.32.32.2-2.32.1-1.61.31.3
Food consumed during 24 hour testing period1.52.12.71.6-1.51.51.6-1.61.6-1.6-1.51.51.4-1.51.4-1.11.10.8
Glucose2.03.14.1-1.71.8-1.8-1.61.6-1.71.61.8-1.8-2.01.9-1.81.5-1.8-1.8
Heart weight1.42.13.21.3-1.61.61.4-1.41.5-1.5-1.61.61.8-1.71.4-0.71.31.2
Delay discount hyperbolic model param0.50.61.30.8-0.70.70.6-0.60.7-0.7-0.70.70.7-0.80.8-1.10.71.0
Intermittent access intake day 1-15 change0.50.91.20.2-1.11.11.0-1.01.0-1.0-1.11.11.1-1.10.9-0.70.80.8
Intermittent access intake escalation0.71.52.00.4-1.41.31.3-1.31.3-1.3-1.31.31.4-1.31.3-1.01.11.1
Intermittent access intake escalation 20.10.10.3-0.4-0.40.40.5-0.50.5-0.5-0.40.40.2-0.4-0.0-0.20.00.1
Intermitt. access day 1 inactive lever presses0.62.43.21.3-1.61.61.5-1.51.5-1.5-1.61.61.8-1.71.5-1.31.51.5
Intermitt. access day 15 inactive lever presses2.24.56.31.0-2.32.32.0-2.02.1-2.1-2.32.32.5-2.52.0-1.91.92.2
Intermitt. access escalation Index0.81.13.0-1.70.8-0.8-0.70.7-0.80.80.8-0.8-0.90.9-1.01.5-1.4-1.4
Intermittent access day 1 total infusions0.40.61.81.3-0.80.80.8-0.80.8-0.8-0.80.80.9-0.80.9-0.30.30.3
Intermittent access day 15 total infusions0.81.31.91.2-1.31.31.1-1.11.1-1.1-1.21.21.4-1.21.3-0.50.60.7
Intermittent access terminal intake (last 3 days)0.81.11.61.2-1.21.21.1-1.11.1-1.1-1.11.11.2-1.21.1-0.30.50.6
Intermittent access total infusions1.61.92.71.7-1.51.51.4-1.41.4-1.4-1.51.51.5-1.51.4-0.70.70.8
Intermittent access day 1 locomotion0.91.21.70.8-1.31.31.3-1.31.3-1.3-1.31.31.3-1.21.0-0.10.30.2
Intermittent access day 15 total locomotion0.61.01.9-0.1-1.21.21.4-1.41.3-1.3-1.21.20.9-1.00.9-0.2-0.0-0.0
Intermittent access total locomotion2.32.73.90.7-1.91.92.0-2.02.0-2.0-1.91.91.8-1.81.6-0.70.80.6
Intermittent access standard deviation0.20.50.9-0.90.6-0.6-0.50.5-0.50.50.6-0.6-0.70.6-0.60.9-1.0-0.8
Left kidney weight4.922.725.65.1-5.05.04.9-4.94.9-4.9-4.84.84.9-4.64.9-4.54.43.9
Right kidney weight5.223.533.35.8-5.05.04.8-4.84.8-4.8-4.94.95.1-4.74.9-4.34.63.9
Cocaine induced anxiety1.01.42.01.1-1.21.21.1-1.11.2-1.2-1.21.21.1-1.21.1-1.41.11.1
Post-drug Anxiety0.91.02.21.2-0.80.80.7-0.60.7-0.7-0.80.81.0-0.91.1-1.41.21.5
Baseline Anxiety0.50.60.8-0.40.8-0.8-0.90.9-0.90.90.9-0.9-0.70.8-0.60.7-0.5-0.4
Tail length3.112.113.43.2-3.73.73.6-3.63.6-3.5-3.63.63.7-3.63.6-3.23.32.9
Length with tail2.812.114.53.6-3.63.63.4-3.43.4-3.4-3.53.53.8-3.43.8-3.13.63.0
Length without tail1.34.37.12.7-2.12.11.8-1.81.8-1.8-1.91.92.4-1.82.5-1.72.42.2
Times rat made contact with spout0.10.10.20.50.3-0.3-0.30.3-0.30.30.3-0.3-0.10.3-0.00.10.10.1
Lifetime Intake1.11.32.01.4-1.31.31.2-1.21.2-1.2-1.31.31.3-1.31.2-0.60.60.7
Liver weight, left0.81.41.71.3-1.31.21.2-1.21.2-1.2-1.21.21.3-1.11.2-0.81.00.8
Liver weight, right0.10.11.11.10.1-0.1-0.00.0-0.00.00.1-0.1-0.10.2-0.1-0.00.3-0.3
Locomotor activity0.10.20.4-0.10.4-0.5-0.50.5-0.50.50.5-0.5-0.30.6-0.30.6-0.3-0.3
Locomotor testing distance0.00.10.40.6-0.10.1-0.10.1-0.10.1-0.00.00.30.00.30.10.30.3
Locomotor testing rearing0.20.51.91.4-0.70.70.7-0.70.7-0.7-0.60.60.7-0.50.7-0.30.50.3
Locomotion in novel chamber2.02.53.5-1.61.5-1.5-1.41.4-1.41.41.5-1.5-1.61.6-1.71.9-1.8-1.8
Locomotion in novel chamber post-restriction0.71.11.9-1.31.0-1.0-1.01.0-1.01.01.0-1.0-0.91.1-1.01.4-1.0-1.1
Fecal boli incidents, locomotor time 10.10.20.30.4-0.50.50.6-0.60.5-0.5-0.50.50.3-0.30.5-0.10.0-0.1
Change in fecal boli incidents, locomotor task3.03.03.9-2.01.7-1.7-1.71.7-1.71.61.7-1.7-1.81.6-1.81.9-1.8-1.6
Time >=10cm from walls, locomotor time 10.00.00.20.40.1-0.1-0.10.1-0.10.10.1-0.10.0-0.00.1-0.10.10.2
Bouts of movement, locomotor time 10.20.20.6-0.2-0.30.40.7-0.70.7-0.7-0.40.4-0.2-0.1-0.1-0.1-0.6-0.8
Total resting periods, locomotor time 10.20.20.9-0.60.1-0.10.1-0.20.1-0.10.1-0.1-0.50.3-0.40.4-0.9-0.9
Rest time, locomotor task time 11.01.21.51.0-1.21.21.2-1.21.2-1.2-1.21.21.2-1.11.2-0.60.70.7
Distance moved, locomotor task time 11.01.61.9-1.31.4-1.4-1.31.3-1.31.31.3-1.3-1.41.3-1.40.7-0.8-0.8
Vertical activity count, locomotor time 11.63.95.4-2.32.0-2.0-1.81.8-1.81.81.9-1.9-2.32.1-2.21.6-2.0-1.9
Time >=10cm from walls, locomotor time 20.40.50.8-0.70.8-0.8-0.90.9-0.90.90.8-0.8-0.60.6-0.60.6-0.5-0.2
Bouts of movement, locomotor time 20.00.00.10.4-0.10.10.1-0.10.1-0.1-0.10.10.00.00.10.1-0.0-0.1
Total resting periods, locomotor time 20.00.00.10.2-0.10.10.1-0.10.1-0.1-0.10.10.0-0.00.00.2-0.2-0.3
Rest time, locomotor task time 20.00.00.3-0.1-0.00.00.2-0.20.2-0.2-0.10.1-0.20.0-0.20.2-0.4-0.5
Distance moved, locomotor task time 20.10.10.3-0.50.4-0.4-0.40.4-0.40.40.4-0.4-0.40.4-0.40.0-0.2-0.1
Vertical activity count, locomotor time 20.30.40.6-0.50.6-0.6-0.50.5-0.60.60.6-0.6-0.80.8-0.60.6-0.8-0.8
Light reinforcement 10.10.10.4-0.70.1-0.10.2-0.20.2-0.2-0.10.1-0.5-0.2-0.6-0.5-0.4-0.5
Light reinforcement 21.11.74.2-2.11.4-1.3-1.21.2-1.21.21.3-1.3-1.51.2-1.40.7-1.4-0.9
Bone: marrow area2.75.910.93.3-2.52.52.4-2.42.4-2.4-2.42.42.6-2.32.5-2.02.11.8
Bone: maximum diameter1.01.86.32.5-1.31.21.2-1.21.2-1.1-1.11.11.3-1.01.5-1.31.41.1
Bone: maximum force3.15.59.13.0-2.42.42.4-2.42.4-2.4-2.42.42.4-2.32.5-2.01.91.7
Bone: maximum moment3.66.39.83.1-2.62.62.6-2.62.6-2.6-2.62.62.5-2.52.7-2.21.91.8
Mean time between licks in bursts0.30.71.7-1.30.8-0.7-0.60.6-0.60.60.6-0.6-0.90.5-1.20.9-1.2-1.1
Mean num. licks in bursts0.20.22.11.4-0.40.40.3-0.30.3-0.3-0.30.30.4-0.40.4-0.20.50.2
Cd content in liver1.82.02.61.0-1.61.61.6-1.61.6-1.6-1.61.61.4-1.51.4-1.20.60.9
Co content in liver1.01.12.0-0.8-1.11.11.2-1.21.3-1.3-1.21.20.8-1.40.9-0.9-0.20.5
Cu content in liver1.31.52.6-0.2-1.21.21.1-1.11.2-1.1-1.31.31.3-1.51.4-1.50.81.6
Fe content in liver0.40.50.8-0.3-0.70.70.6-0.60.7-0.6-0.70.70.7-0.80.7-0.90.50.9
K content in liver0.10.00.3-0.2-0.00.00.0-0.00.0-0.0-0.10.10.1-0.20.3-0.50.20.5
Mg content in liver0.10.10.3-0.20.2-0.2-0.40.4-0.30.30.2-0.20.00.10.1-0.00.10.5
Mn content in liver0.10.10.70.30.1-0.1-0.20.2-0.20.20.1-0.10.10.10.1-0.50.80.8
Na content in liver2.52.73.4-1.61.8-1.8-1.81.8-1.81.81.8-1.8-1.81.7-1.71.0-1.1-0.8
Rb content in liver3.54.06.41.8-1.91.91.7-1.71.7-1.7-1.91.92.1-2.02.2-2.52.42.5
Se content in liver2.32.73.7-0.51.8-1.8-1.81.8-1.81.81.8-1.8-1.61.9-1.61.5-1.2-1.1
Sr content in liver6.05.28.2-2.92.3-2.3-2.02.0-2.12.02.2-2.2-2.62.2-2.62.0-2.4-2.2
Zn content in liver0.40.41.1-1.10.6-0.6-0.80.8-0.80.80.7-0.7-0.20.5-0.40.8-0.50.1
Bone: minimum diameter3.36.012.13.5-2.42.42.5-2.52.4-2.4-2.42.42.3-2.32.4-2.52.31.7
Time in familiar zone, hab. session 12.22.13.80.7-1.61.61.9-1.91.9-1.9-1.71.71.1-1.51.1-0.4-0.2-0.4
Time in novel zone, hab. session 11.91.92.9-1.31.6-1.6-1.71.7-1.61.71.5-1.5-1.31.4-1.20.4-0.40.0
Total zone transitions, hab. session 10.60.91.6-0.2-0.91.01.2-1.31.2-1.3-1.11.10.4-1.20.3-1.10.4-0.0
Total locomotion distance, hab. session 10.20.30.5-0.7-0.40.40.7-0.70.7-0.7-0.60.6-0.0-0.6-0.2-0.3-0.3-0.5
Locomotion velocity, hab. session 10.20.20.5-0.7-0.40.40.6-0.60.6-0.6-0.50.50.0-0.5-0.1-0.2-0.1-0.4
Time in familiar zone, hab. session 22.42.63.81.9-1.71.71.5-1.51.5-1.5-1.61.61.9-1.52.0-1.01.41.4
Time in novel zone, hab. session 21.41.52.3-1.51.3-1.3-1.31.3-1.21.21.2-1.2-1.41.1-1.40.6-0.9-0.7
Total zone transitions, hab. session 21.92.53.51.9-1.61.61.8-1.81.8-1.8-1.61.61.1-1.51.1-1.81.30.5
Total locomotion distance, hab. session 20.10.10.60.2-0.00.10.3-0.30.3-0.3-0.20.2-0.3-0.1-0.4-0.1-0.2-0.8
Locomotion velocity, hab. session 20.10.10.80.00.1-0.10.2-0.20.2-0.2-0.00.0-0.50.0-0.6-0.0-0.3-0.9
Novel to familiar place preference ratio0.00.00.30.5-0.10.10.0-0.00.0-0.0-0.00.00.1-0.00.2-0.20.30.2
Novelty place preference0.10.10.40.7-0.30.30.3-0.30.3-0.3-0.30.30.3-0.20.3-0.40.40.3
Time in novel zone, NPP test0.10.10.60.8-0.30.30.3-0.30.3-0.3-0.30.30.3-0.20.4-0.30.30.2
Total zone transitions, NPP test0.20.30.50.7-0.50.50.7-0.70.6-0.6-0.50.50.1-0.40.3-0.40.3-0.3
Total locomotion distance, NPP test0.30.41.31.1-0.60.60.6-0.60.6-0.6-0.60.60.4-0.50.6-0.70.80.3
Locomotion velocity, NPP test0.30.41.01.0-0.60.60.7-0.70.7-0.7-0.60.60.4-0.50.6-0.90.80.3
Intraocular pressure0.00.10.2-0.40.1-0.1-0.10.1-0.10.10.0-0.0-0.1-0.10.2-0.50.50.5
Delta distance traveled before/after self-admin2.32.43.0-1.21.7-1.7-1.71.7-1.71.71.7-1.7-1.51.7-1.61.5-1.1-1.1
Delta ambulatory time before/after self-admin1.41.72.1-0.81.4-1.4-1.41.4-1.41.41.4-1.4-1.41.4-1.31.3-1.1-1.0
Parametrial fat weight2.04.65.5-1.82.2-2.2-2.22.2-2.22.22.3-2.3-2.12.4-1.92.2-1.9-1.8
Pavlov. Cond. lever latency0.10.10.6-0.70.3-0.3-0.30.3-0.20.20.2-0.2-0.30.2-0.1-0.1-0.20.1
Pavlov. Cond. magazine entry latency0.60.71.1-0.80.9-0.9-1.01.0-1.01.00.9-0.9-0.60.8-1.01.1-0.6-0.5
Pavlov. Cond. change in total contacts0.30.40.5-0.30.6-0.6-0.60.6-0.60.60.6-0.6-0.60.6-0.70.7-0.5-0.7
Pavlov. Cond. index score0.40.51.1-0.60.6-0.6-0.60.6-0.60.60.6-0.6-0.60.6-0.91.0-0.6-0.8
Pavlov. Cond. latency score0.30.41.1-0.40.5-0.5-0.50.5-0.50.50.5-0.5-0.50.6-0.91.1-0.6-0.9
Pavlov. Cond. lever contacts0.10.11.51.2-0.30.30.2-0.20.2-0.2-0.20.20.4-0.10.2-0.00.50.1
Pavlov. Cond. magazine entry number0.20.30.60.4-0.50.50.6-0.60.6-0.6-0.50.50.4-0.50.7-0.80.30.4
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.30.3-0.30.0-0.10.0-0.00.1-0.1-0.70.2-0.3-0.6-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.50.6-0.6-0.60.6-0.60.60.6-0.6-0.60.6-0.91.0-0.6-0.8
Pavlov. Cond. response bias0.00.00.10.30.1-0.1-0.20.2-0.20.20.1-0.10.10.1-0.10.30.30.1
Pavlov. Cond. lever latency0.30.41.21.1-0.60.60.7-0.70.7-0.7-0.70.70.5-0.70.3-0.00.2-0.2
Pavlov. Cond. magazine entry latency0.60.81.2-0.51.0-1.0-1.11.1-1.11.11.0-1.0-0.81.0-0.60.4-0.6-0.1
Pavlov. Cond. change in total contacts0.20.31.4-0.5-0.40.40.4-0.40.4-0.4-0.40.40.3-0.40.6-1.20.50.9
Pavlov. Cond. index score0.10.10.6-0.50.2-0.2-0.30.3-0.20.20.2-0.2-0.00.10.2-0.60.30.8
Pavlov. Cond. latency score0.30.30.7-0.80.6-0.6-0.70.7-0.70.70.6-0.6-0.40.6-0.2-0.2-0.10.5
Pavlov. Cond. lever contacts0.10.20.8-0.90.3-0.3-0.40.4-0.30.30.3-0.3-0.20.30.1-0.40.10.6
Pavlov. Cond. magazine entry number0.40.51.11.1-0.70.70.8-0.80.8-0.8-0.80.80.6-0.70.4-0.50.70.1
Pavlov. Cond. intertrial magazine entries2.84.24.91.5-2.22.22.2-2.22.2-2.2-2.22.22.1-2.21.8-1.81.81.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.7-0.90.3-0.3-0.40.4-0.30.30.3-0.3-0.20.20.0-0.3-0.00.6
Pavlov. Cond. response bias0.20.31.3-0.0-0.40.40.3-0.30.3-0.3-0.40.40.5-0.40.7-1.00.71.1
Time in closed arm before self-admin0.81.01.50.6-1.01.01.0-1.01.0-1.0-1.01.01.0-0.91.0-1.21.21.1
Time in closed arm after self-admin0.30.30.90.9-0.40.30.2-0.20.2-0.2-0.30.30.6-0.40.7-0.60.91.0
Time in open arm before self-admin2.02.22.6-1.01.6-1.6-1.51.5-1.51.51.5-1.5-1.51.5-1.41.6-1.5-1.4
Time in open arm after self-admin0.30.41.1-1.10.5-0.5-0.30.3-0.40.30.5-0.5-0.70.5-0.80.5-0.9-0.8
Bone: periosteal estimation2.14.48.93.0-2.12.12.1-2.12.1-2.1-2.12.12.1-1.92.2-1.91.81.5
Bone: periosteal perimeter1.72.94.62.1-1.71.71.7-1.71.7-1.7-1.71.71.6-1.61.8-1.71.41.2
Bone: post-yield work3.14.65.82.4-2.22.22.0-2.02.0-2.0-2.12.12.4-2.12.4-2.02.12.2
Progressive ratio test 1 active lever presses0.91.14.02.0-1.01.01.2-1.21.1-1.2-1.11.10.7-1.10.7-0.90.30.2
Progressive ratio test 1 breakpoint0.91.14.12.0-1.01.01.2-1.21.1-1.1-1.11.10.7-1.10.7-0.90.30.2
Progressive ratio test 1 inactive lever presses3.14.55.82.2-2.22.22.2-2.22.3-2.3-2.32.32.1-2.41.9-1.81.41.4
Progressive ratio test 2 active lever presses0.91.13.51.9-1.01.00.8-0.80.9-0.8-1.01.01.1-1.01.1-0.80.90.9
Progressive ratio test 2 breakpoint1.11.33.71.9-1.11.10.9-0.90.9-0.9-1.01.01.2-1.11.3-0.91.01.0
Progressive ratio test 2 inactive lever presses2.84.65.61.7-2.32.32.3-2.32.3-2.3-2.42.32.3-2.42.1-1.71.51.5
Incentive Sensitization - Responses1.52.23.31.7-1.51.51.2-1.21.3-1.2-1.41.41.8-1.41.8-1.41.61.7
Incentive Sensitization - Breakpoint1.11.52.41.3-1.21.21.0-0.91.0-1.0-1.11.11.5-1.21.6-1.11.41.5
Sum of active levers in priming session hrs 5-60.20.21.7-1.30.2-0.2-0.10.1-0.10.10.2-0.2-0.40.3-0.60.3-0.2-0.5
Progressive ratio0.00.00.40.6-0.00.00.1-0.10.1-0.1-0.10.1-0.2-0.0-0.1-0.3-0.2-0.1
Food seeking constrained by brief footshock0.60.73.7-0.90.1-0.00.7-0.70.6-0.6-0.20.2-1.10.1-1.20.3-1.5-1.9
Seeking ratio, punishment vs. effort0.30.40.7-0.2-0.70.70.9-0.90.8-0.8-0.70.70.4-0.60.2-0.20.2-0.2
Retroperitoneal fat weight3.816.120.6-2.04.3-4.3-4.54.5-4.54.54.4-4.4-3.74.4-3.64.1-2.9-2.7
Reaction time number correct0.20.52.2-0.40.5-0.5-0.40.4-0.50.50.5-0.5-0.60.6-0.40.9-1.5-1.0
Reaction time mean minus median0.10.22.7-1.6-0.00.00.0-0.00.0-0.0-0.00.00.0-0.0-0.20.6-0.3-0.3
Reaction time mean minus median AUC0.00.11.3-1.10.1-0.1-0.10.1-0.10.10.1-0.10.00.0-0.20.4-0.3-0.1
Reaction time num false alarms0.10.12.0-1.4-0.10.10.0-0.00.1-0.1-0.10.10.1-0.30.0-0.0-0.20.2
Reaction time num false alarms AUC0.40.55.8-2.40.4-0.4-0.30.3-0.30.30.3-0.3-0.50.2-0.60.4-0.8-0.5
Reaction time trials correct on left0.20.52.2-0.40.5-0.5-0.40.4-0.50.50.5-0.5-0.60.6-0.40.9-1.5-1.0
Reaction time trials on left0.20.52.2-0.50.5-0.5-0.40.4-0.40.40.5-0.5-0.60.6-0.40.9-1.5-1.0
Reaction time mean0.81.32.2-0.3-1.21.10.9-0.91.0-1.0-1.11.11.4-1.31.2-1.11.31.5
Reaction time mean AUC0.30.51.2-0.5-0.70.70.5-0.50.5-0.5-0.70.71.0-0.90.8-0.60.91.1
Median of all reaction times1.01.43.00.1-1.21.20.9-0.91.0-1.0-1.11.11.5-1.41.3-1.31.51.7
Reaction time omissions0.20.44.7-2.20.1-0.1-0.0-0.00.0-0.0-0.00.0-0.3-0.1-0.50.0-0.4-0.1
Reaction time false alarm rate0.20.34.0-2.00.1-0.1-0.00.0-0.00.0-0.00.0-0.1-0.1-0.3-0.1-0.10.1
Reaction time premature initiation rate0.00.00.20.2-0.00.00.0-0.0-0.00.0-0.00.00.10.00.20.10.40.0
Reaction time premature initiations0.10.10.30.00.3-0.3-0.30.3-0.30.30.4-0.4-0.20.4-0.10.5-0.3-0.4
Std. dev. reaction times0.30.61.0-0.8-0.80.80.7-0.70.7-0.7-0.80.81.0-0.90.7-0.50.70.8
Reaction time trials completed0.20.52.2-0.50.5-0.5-0.40.4-0.40.40.5-0.5-0.60.6-0.40.9-1.5-1.0
Reaction time trials AUC0.20.41.8-0.30.5-0.5-0.40.4-0.40.40.5-0.5-0.50.6-0.40.9-1.3-0.9
Run reversals in cocaine runway, females0.70.71.80.9-0.70.70.5-0.50.6-0.6-0.70.70.9-0.80.8-1.01.31.2
Run reversals in cocaine runway, males0.00.00.1-0.3-0.20.20.1-0.10.1-0.1-0.20.20.2-0.20.2-0.20.30.3
Latency to leave start box in cocaine runway0.70.71.20.3-0.90.90.8-0.80.8-0.8-0.90.90.9-0.91.1-1.00.91.0
Latency to leave start box in cocaine runway, F0.10.10.3-0.0-0.30.30.3-0.30.3-0.3-0.30.30.4-0.30.5-0.60.40.5
Latency to leave start box in cocaine runway, M1.51.41.70.6-1.31.21.2-1.21.2-1.2-1.21.21.3-1.31.3-1.01.21.2
Std. dev. time between licks in bursts0.20.21.3-1.20.2-0.20.1-0.10.1-0.10.0-0.0-0.6-0.1-0.8-0.2-0.8-0.7
Total sessions with >9 infusions0.81.01.50.6-1.11.11.2-1.21.2-1.2-1.21.20.9-1.10.7-0.60.40.2
Short access day 1 total inactive lever presses0.81.01.60.8-1.11.10.9-0.90.9-0.9-1.01.01.3-1.11.1-0.71.11.0
Short access day 10 total inactive lever presses0.10.20.6-0.7-0.40.40.4-0.40.4-0.4-0.40.40.5-0.40.4-0.10.40.4
Short access day 1 total infusions0.00.00.1-0.3-0.10.10.1-0.10.2-0.2-0.20.20.1-0.2-0.00.2-0.1-0.2
Short access day 10 total infusions0.00.10.30.00.1-0.1-0.00.0-0.00.00.0-0.0-0.20.1-0.20.5-0.5-0.6
Short access total infusions0.10.10.4-0.20.1-0.1-0.10.1-0.10.10.1-0.1-0.10.0-0.30.6-0.4-0.5
Short access day 1 locomotion0.30.40.60.8-0.70.70.7-0.70.7-0.7-0.70.70.7-0.70.7-0.10.50.2
Short access day 10 total locomotion0.30.61.1-1.0-0.80.81.0-1.01.0-1.0-0.80.80.3-0.60.20.2-0.3-0.6
Short access total locomotion0.30.41.5-0.6-0.40.40.7-0.70.6-0.6-0.50.5-0.1-0.2-0.30.7-0.8-1.2
One hour access (0.3 mA shock)4.04.65.71.7-2.42.42.3-2.32.3-2.3-2.32.32.4-2.32.3-1.61.51.7
Compulsive drug intake1.72.13.10.9-1.51.51.4-1.41.4-1.4-1.41.41.5-1.41.7-1.61.11.5
One hour access (shock baseline)0.50.82.61.6-0.90.90.7-0.70.8-0.7-0.90.91.1-1.10.8-0.30.50.6
Social response proportion1.11.22.10.5-1.11.10.9-0.90.9-0.9-1.11.11.4-1.31.2-0.91.41.4
Social responses3.74.85.81.8-2.22.22.1-2.12.1-2.1-2.22.22.3-2.42.2-2.32.42.2
Social time2.63.55.41.1-2.12.12.3-2.32.3-2.3-2.22.21.6-2.01.4-1.41.00.6
Soleus weight0.00.10.50.7-0.20.20.2-0.20.2-0.2-0.10.10.1-0.20.00.00.2-0.2
Bone: stiffness2.54.14.91.7-2.22.22.1-2.12.1-2.1-2.22.22.2-2.22.2-1.71.41.7
Tibialis anterior weight0.93.04.80.81.9-1.9-1.91.9-2.02.02.0-2.0-1.72.2-1.41.4-0.9-1.4
Time to tail flick, vehicle, before self-admin0.30.30.5-0.2-0.60.60.7-0.70.7-0.7-0.60.60.3-0.50.5-0.50.10.2
Time to tail flick, vehicle, after self-admin0.20.30.80.1-0.60.60.4-0.40.5-0.5-0.50.50.9-0.60.6-0.10.90.6
Time to tail flick, test, before self-admin0.50.52.0-0.80.5-0.5-0.20.2-0.20.20.4-0.4-1.00.7-0.80.7-1.0-1.4
Time to tail flick, test, after self-admin0.10.10.2-0.10.3-0.3-0.40.4-0.40.40.3-0.3-0.20.2-0.40.20.00.0
Delta time to tail flick, vehicle, before/after SA0.10.10.7-0.20.2-0.2-0.50.5-0.40.40.3-0.30.10.2-0.20.80.1-0.0
Delta time to tail flick, test, before/after SA0.40.41.60.7-0.50.50.2-0.20.3-0.3-0.50.50.8-0.60.7-0.81.01.3
Tibia length3.69.915.74.0-3.23.23.1-3.13.1-3.1-3.13.13.2-3.03.2-2.83.12.5
Ambulatory time before self-admin0.91.32.5-0.3-1.21.21.6-1.61.5-1.5-1.31.30.7-1.10.5-1.20.50.1
Ambulatory time after self-admin0.20.31.5-1.20.1-0.10.3-0.30.2-0.3-0.10.1-0.60.1-0.80.2-0.8-0.9
Bone: tissue strength0.30.31.70.4-0.20.20.5-0.50.5-0.5-0.30.3-0.3-0.1-0.40.4-0.9-1.3
Total heroin consumption0.00.00.3-0.20.1-0.1-0.00.0-0.10.10.1-0.1-0.30.2-0.50.3-0.2-0.4
Bone: trabecular number0.20.31.0-1.00.4-0.4-0.40.4-0.40.40.4-0.4-0.50.4-0.60.7-0.6-0.7
Bone: trabecular spacing0.10.22.51.60.0-0.0-0.10.1-0.10.10.1-0.10.00.10.2-0.20.30.1
Bone: trabecular thickness0.00.00.1-0.2-0.10.10.1-0.10.1-0.1-0.20.20.1-0.20.00.00.10.0
Bone: trabecular tissue density0.50.81.3-0.51.0-1.0-1.11.1-1.11.11.1-1.1-0.71.0-0.70.6-0.2-0.1
Water consumed over 24 hours0.70.91.40.9-1.01.01.2-1.21.2-1.2-1.11.10.8-1.00.8-0.80.50.2
Number of responses in last shaping day0.00.00.20.1-0.20.20.1-0.10.1-0.1-0.20.20.4-0.40.00.40.1-0.0