Hub : Genes

Zfp575

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Zfp575 0.48 0.13 5.3e-09 0.02 0.07 0.05 0.04 9.6e-04 2.8e-08 2.1e-06 1.0e-05
2 NAcc mRNA stability Zfp575 0.31 0.12 8.5e-12 0.05 0.08 0.07 0.07 1.2e-08 3.0e-12 1.6e-11 7.1e-11
3 OFC gene expression Zfp575 0.43 0.25 4.7e-05 0.09 0.16 0.12 0.12 3.1e-03 1.1e-04 7.6e-04 9.4e-04
4 PL gene expression Zfp575 0.04 0.03 1.8e-04 0.03 0.03 0.03 0.03 2.7e-04 4.2e-04 1.2e-04 3.0e-04
5 pVTA gene expression Zfp575 0.08 0.06 6.1e-05 0.06 0.05 0.05 0.06 2.1e-05 1.1e-04 9.8e-05 3.2e-05
6 NAcc gene expression Zfp575 0.05 0.04 8.2e-06 0.03 0.02 0.02 0.03 8.2e-06 1.8e-04 1.8e-04 1.9e-05
7 Brain mRNA stability Zfp575 0.04 0.04 6.9e-03 0.04 0.01 0.02 0.03 2.6e-04 6.1e-02 6.0e-03 1.7e-03
8 Brain gene expression Zfp575 0.07 0.05 3.0e-06 0.06 0.06 0.05 0.06 4.0e-06 2.4e-06 8.9e-06 4.0e-06
9 IC gene expression Zfp575 0.3 0.15 4.2e-08 0.12 0.12 0.12 0.11 7.5e-06 9.3e-06 1.3e-05 3.3e-05
10 IC mRNA stability Zfp575 0.17 0.1 6.6e-06 0.12 0.1 0.1 0.11 1.2e-05 3.9e-05 7.2e-05 1.8e-05
11 pVTA intron excision ratio chr1_89304300_89304567 0.05 0.04 4.0e-03 0.01 0.01 0.01 0 7.8e-02 2.3e-02 3.1e-02 1.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.20.60.70.2-0.40.6-0.60.40.4-0.40.30.2-0.4
Area under the delay curve0.20.31.5-0.1-0.10.7-0.30.3-0.4-0.50.3-0.7-0.1-1.2
BMI with tail0.82.74.3-1.6-1.7-2.12.0-2.01.61.4-2.01.50.8-0.9
BMI without tail0.21.22.00.5-0.1-1.31.2-1.21.31.0-1.21.41.2-0.3
Body weight1.56.49.1-1.5-1.7-2.82.9-2.93.02.7-2.82.92.5-1.5
Weight adjusted by age0.71.914.13.82.50.3-0.20.20.2-0.10.30.40.50.3
Bone surface0.40.81.3-0.8-0.9-1.11.1-1.10.80.7-1.10.70.4-0.6
Bone volume0.40.81.2-0.1-0.7-0.91.1-1.11.11.0-1.01.00.7-0.8
Breakpoint value in progressive ratio session0.61.01.90.20.61.4-1.31.2-1.0-1.21.1-1.0-1.1-0.4
Number of licking bursts0.51.63.0-0.1-1.1-1.21.3-1.31.51.5-1.31.71.4-0.7
Context. condit. distance diff. score0.20.20.40.10.0-0.60.6-0.60.50.3-0.60.40.5-0.4
Locomotion velocity, session 10.10.20.8-0.3-0.9-0.10.2-0.2-0.1-0.1-0.3-0.1-0.1-0.8
Locomotion distance, session 10.30.30.7-0.1-0.7-0.50.5-0.50.80.7-0.60.60.1-0.6
Locomotion velocity, session 20.10.10.60.2-0.8-0.40.1-0.1-0.2-0.1-0.20.10.10.5
Locomotion distance, session 20.20.32.4-0.5-1.5-0.30.1-0.10.10.1-0.20.0-0.50.5
Locomotion velocity, session 30.20.20.7-0.5-0.8-0.1-0.20.2-0.2-0.50.1-0.3-0.80.7
Locomotion distance, session 32.93.34.61.61.21.6-1.91.9-1.8-2.01.9-1.8-2.12.0
Stereotopy head waving bouts, day 30.20.21.60.10.3-0.4-0.10.10.30.20.00.20.21.3
Stereotopy head waving duration, day 30.70.91.5-1.0-1.2-1.21.0-1.00.90.9-1.00.90.6-0.0
Locomotion velocity, session 70.40.41.2-0.6-1.10.1-0.10.1-0.9-0.80.1-0.8-1.00.0
Locomotion distance, session 70.30.31.2-0.6-1.1-0.60.7-0.70.20.2-0.60.2-0.2-0.5
Stereotopy head waving bouts, day 70.20.21.0-1.0-0.3-0.80.4-0.40.10.1-0.5-0.1-0.20.6
Stereotopy head waving duration, day 70.20.30.9-0.9-0.6-0.90.6-0.60.30.3-0.70.10.10.1
Locomotion velocity, session 80.91.12.10.1-0.10.6-0.91.0-1.3-1.40.8-1.4-1.51.1
Locomotion distance, session 80.10.10.20.5-0.4-0.20.3-0.30.50.3-0.30.40.2-0.2
Degree of sensitization distance3.73.95.0-1.8-1.7-1.82.2-2.21.92.0-2.21.91.8-2.2
Degree of sensitization stereotypy0.20.20.7-0.7-0.3-0.80.5-0.50.20.2-0.6-0.10.10.4
Conditioned locomotion2.93.46.71.11.01.3-1.91.9-2.0-2.01.8-2.1-2.02.6
Cocaine response after cond. corrected0.20.20.6-0.2-0.2-0.50.3-0.30.60.7-0.20.70.40.8
Cocaine response after cond. not corrected0.30.41.6-0.3-0.5-0.80.4-0.40.70.8-0.40.80.41.3
Cocaine response before conditioning0.20.31.8-0.3-0.5-0.70.2-0.20.00.1-0.20.1-0.21.3
Saline control response0.91.22.4-0.8-1.2-1.61.4-1.40.90.9-1.40.90.8-0.6
Bone: connectivity density0.10.20.2-0.5-0.3-0.40.5-0.5-0.3-0.3-0.4-0.3-0.5-0.4
Bone: cortical apparent density0.20.30.90.50.50.10.2-0.20.60.6-0.10.71.0-0.6
Bone: cortical area1.11.83.21.2-0.2-1.31.3-1.31.71.8-1.21.71.5-0.5
Bone: cortical porosity4.44.89.21.01.51.9-2.52.5-2.2-2.32.4-2.1-2.13.0
Bone: cortical porosity2.73.07.30.61.11.3-1.91.9-1.7-1.71.9-1.7-1.62.7
Bone: cortical thickness0.60.92.21.50.1-0.70.7-0.71.31.4-0.61.21.1-0.1
Bone: cortical thickness0.70.91.90.1-0.5-1.00.8-0.81.31.4-0.81.31.00.2
Bone: cortical tissue density0.10.20.70.40.50.20.1-0.10.50.50.00.50.8-0.5
Condit. Reinf. active minus inactive responses0.30.40.9-0.4-0.3-0.80.7-0.70.90.6-0.60.80.3-0.0
Condit. Reinf. active-inactive response ratio0.70.71.2-0.6-0.7-1.11.1-1.11.00.7-1.01.00.4-0.4
Condit. Reinf. active responses0.10.10.4-0.6-0.1-0.60.5-0.50.30.1-0.40.20.20.1
Condit. Reinf. inactive responses0.10.10.4-0.30.60.0-0.20.2-0.5-0.30.1-0.50.10.1
Incentive salience index mean0.10.10.4-0.20.1-0.2-0.00.0-0.1-0.30.0-0.2-0.40.6
Condit. Reinf. lever presses0.40.61.4-0.30.00.3-0.60.5-1.1-1.10.5-1.2-1.10.6
Condit. Reinf. active minus inactive responses0.10.20.7-0.8-0.9-0.30.1-0.1-0.1-0.1-0.10.0-0.60.4
Condit. Reinf. active-inactive response ratio0.10.21.6-0.6-0.4-0.4-0.00.00.20.20.00.2-0.01.3
Condit. Reinf. active responses0.30.41.7-0.1-0.30.4-0.50.5-0.7-0.80.5-0.6-1.30.6
Condit. Reinf. inactive responses0.50.82.30.40.20.8-0.70.7-1.2-1.20.7-1.1-1.5-0.1
Condit. Reinf. lever presses0.91.21.7-0.0-1.0-1.11.3-1.31.21.2-1.31.30.8-1.1
Condit. Reinf. lever reinforcers received0.50.62.3-0.1-0.30.5-0.70.7-0.9-0.90.7-0.8-1.50.8
Conditioned reinforcement - actives0.31.12.4-1.3-0.6-1.51.1-1.11.10.9-1.21.10.80.3
Conditioned reinforcement - inactives0.41.05.0-2.2-2.0-0.70.5-0.50.60.4-0.50.4-0.20.3
Conditioned locomotion0.91.32.9-1.7-1.2-1.61.2-1.20.90.9-1.30.80.80.4
Patch foraging indifference point 0 sec0.20.53.21.80.5-0.50.2-0.2-0.4-0.4-0.3-0.4-1.10.3
Patch foraging indifference point AUC0.71.73.5-1.9-1.8-1.71.4-1.51.01.1-1.40.80.10.1
Delay disc. indifference point, 0s delay2.32.64.42.01.81.4-1.61.5-1.5-1.71.4-2.1-1.60.6
Delay disc. indifference point, 16s delay0.30.52.5-1.1-0.90.40.2-0.20.30.1-0.20.10.5-1.6
Delay disc. indifference point, 2s delay0.60.73.30.60.51.1-0.40.4-0.8-0.50.4-1.0-0.1-1.8
Delay disc. indifference point, 24s delay1.52.56.8-1.9-2.6-1.31.8-1.80.71.1-1.60.41.1-1.6
Delay disc. indifference point, 4s delay0.00.10.2-0.00.4-0.0-0.20.20.40.00.10.3-0.20.2
Delay disc. indifference point, 8s delay0.20.41.10.1-0.10.9-0.40.4-0.7-0.70.4-0.9-0.2-1.0
Indifference point function ln k0.10.41.71.30.90.9-0.60.6-0.2-0.30.7-0.00.2-0.3
Indifference point function log k0.10.41.71.30.90.9-0.60.6-0.2-0.30.7-0.00.2-0.3
Patch foraging total patch changes 0 sec0.20.52.01.40.1-1.00.8-0.7-0.1-0.0-0.8-0.0-0.7-0.2
Patch foraging total patch changes 12 sec0.30.51.7-0.6-1.0-0.70.2-0.30.20.4-0.30.1-1.31.0
Patch foraging total patch changes 18 sec1.02.44.8-1.3-1.5-2.22.0-2.11.21.3-2.11.10.2-0.9
Patch foraging total patch changes 24 sec0.41.34.9-2.2-1.9-1.10.9-0.90.50.5-1.00.4-0.9-0.2
Patch foraging total patch changes 6 sec0.30.51.7-0.3-0.5-1.30.7-0.7-0.1-0.1-0.8-0.1-1.00.8
Patch foraging time to switch 0 sec0.51.94.1-1.40.82.0-1.81.8-1.2-1.31.7-1.1-0.9-0.1
Patch foraging water rate 0 sec0.62.25.2-0.6-1.7-2.32.0-2.01.11.3-1.91.00.80.1
Patch foraging water rate 12 sec0.10.51.1-0.3-0.9-0.91.0-1.10.00.1-0.90.20.3-0.6
Patch foraging water rate 18 sec0.51.11.7-0.0-0.7-1.11.3-1.30.91.0-1.20.81.1-1.2
Patch foraging water rate 24 sec0.60.91.5-0.2-1.0-1.21.2-1.10.91.0-1.10.90.7-0.5
Patch foraging water rate 6 sec2.94.27.7-2.6-2.8-1.92.2-2.21.71.7-2.21.71.4-1.9
Seeking ratio, delayed vs. immediate footshock4.05.716.54.13.41.9-2.22.2-1.6-1.42.0-2.1-2.51.2
Distance traveled before self-admin0.71.512.13.51.9-0.10.1-0.20.2-0.2-0.1-0.40.9-0.0
Distance traveled after self-admin1.12.08.72.92.31.0-1.11.2-0.8-1.11.1-0.9-0.20.9
Extensor digitorum longus weight2.39.014.1-0.2-1.7-3.03.2-3.23.83.7-3.13.73.4-2.1
Bone: elastic displacement1.01.31.91.11.21.2-1.21.2-1.3-1.41.2-1.1-1.10.7
Bone: elastic work0.50.63.11.81.10.2-0.50.5-0.4-0.40.5-0.4-0.21.1
Bone: endosteal estimation0.00.10.4-0.5-0.6-0.20.0-0.0-0.1-0.1-0.2-0.2-0.3-0.1
Bone: endosteal perimeter0.10.10.50.2-0.2-0.20.4-0.40.40.3-0.40.50.3-0.7
Epididymis fat weight0.10.51.2-1.1-0.71.0-0.90.9-0.4-0.40.8-0.3-0.7-0.1
Delta time in closed arm before/after self-admin0.50.51.20.5-0.0-0.40.8-0.80.71.0-0.70.70.6-1.1
Delta time in open arm before/after self-admin0.60.73.3-1.8-1.20.5-0.40.4-0.5-0.30.5-0.6-1.10.6
Diff in mean of infusions in LGA sessions0.30.61.0-0.70.10.9-0.70.8-1.0-1.00.7-0.9-0.9-0.4
Delay discount exponential model param0.20.21.50.20.3-0.50.1-0.10.20.3-0.10.5-0.01.2
Extinction: sum of active levers before priming1.11.74.12.01.90.9-1.51.4-0.5-1.01.1-0.6-1.41.2
Active lever presses in extinction session 60.90.96.0-2.4-1.4-0.50.3-0.30.80.5-0.50.70.0-0.6
Bone: final force0.40.61.41.0-0.2-0.70.5-0.51.11.2-0.61.00.9-0.0
Bone: final moment0.50.71.51.20.0-0.80.5-0.51.21.2-0.71.00.90.2
Food consumed during 24 hour testing period1.42.85.7-0.11.01.8-1.81.8-1.9-1.91.7-1.9-2.40.3
Glucose0.30.51.20.60.40.5-0.40.4-1.1-1.10.5-1.0-0.90.4
Heart weight0.61.01.90.5-0.1-1.41.1-1.21.21.1-1.11.21.10.1
Delay discount hyperbolic model param0.20.21.60.10.2-0.50.0-0.00.20.3-0.00.50.11.3
Intermittent access intake day 1-15 change0.31.42.5-1.2-0.3-1.01.2-1.21.31.3-1.21.41.6-1.1
Intermittent access intake escalation0.31.62.7-1.2-0.3-1.11.3-1.31.41.3-1.31.41.7-1.1
Intermittent access intake escalation 20.50.84.92.21.9-0.10.0-0.0-0.1-0.10.10.10.40.3
Intermitt. access day 1 inactive lever presses0.00.21.01.00.2-0.10.4-0.40.20.1-0.20.30.5-0.4
Intermitt. access day 15 inactive lever presses0.31.63.30.2-0.2-0.91.4-1.41.41.3-1.21.41.4-1.8
Intermitt. access escalation Index0.10.21.4-0.4-0.30.5-0.40.4-0.2-0.20.3-0.3-1.2-0.3
Intermittent access day 1 total infusions0.72.05.6-2.4-2.1-1.71.4-1.41.21.1-1.51.00.4-0.1
Intermittent access day 15 total infusions1.94.716.0-4.0-2.7-1.91.9-1.91.91.9-2.01.81.0-1.3
Intermittent access terminal intake (last 3 days)2.34.011.4-3.4-2.7-2.01.9-1.91.81.8-2.01.60.9-1.1
Intermittent access total infusions4.75.516.3-4.0-3.2-2.32.2-2.22.12.1-2.31.91.3-1.0
Intermittent access day 1 locomotion0.40.63.6-1.9-1.1-0.4-0.10.1-0.2-0.2-0.1-0.5-1.00.9
Intermittent access day 15 total locomotion0.10.41.1-1.1-0.2-0.80.6-0.60.60.6-0.70.30.4-0.1
Intermittent access total locomotion2.02.49.1-3.0-1.8-1.71.3-1.31.31.2-1.41.01.00.0
Intermittent access standard deviation0.00.11.0-1.00.40.1-0.00.00.0-0.10.00.20.5-0.2
Left kidney weight1.310.518.8-1.8-2.3-4.33.5-3.53.93.7-3.53.62.90.5
Right kidney weight1.711.618.9-2.6-2.7-4.33.6-3.74.03.9-3.73.83.0-0.1
Cocaine induced anxiety0.61.67.2-2.6-2.7-0.10.6-0.60.70.8-0.50.60.2-1.3
Post-drug Anxiety1.82.112.0-3.5-2.7-0.20.5-0.50.70.7-0.50.5-0.3-1.0
Baseline Anxiety0.81.36.12.52.10.4-0.70.7-0.7-0.70.7-0.6-0.41.0
Tail length0.21.23.11.81.0-0.80.7-0.81.10.9-0.71.31.6-0.2
Length with tail0.52.24.1-0.4-0.7-1.31.4-1.52.01.9-1.32.01.9-0.8
Length without tail1.36.711.4-3.4-3.0-2.22.5-2.52.82.8-2.42.61.9-2.0
Times rat made contact with spout0.20.30.70.80.80.1-0.20.20.40.40.20.50.70.5
Lifetime Intake3.64.413.1-3.6-2.9-2.11.9-1.91.91.8-2.01.71.1-0.7
Liver weight, left0.30.51.1-0.2-0.4-1.00.6-0.60.90.8-0.60.80.40.9
Liver weight, right0.81.32.8-0.6-0.8-1.71.5-1.51.21.1-1.51.10.6-0.4
Locomotor activity0.30.40.9-0.3-0.4-0.90.6-0.60.80.7-0.70.90.60.4
Locomotor testing distance0.30.62.1-1.5-1.1-0.80.6-0.60.80.7-0.70.80.4-0.0
Locomotor testing rearing1.03.67.1-0.8-1.0-2.72.2-2.22.02.0-2.31.92.0-0.5
Locomotion in novel chamber0.30.42.21.50.80.6-0.60.6-0.3-0.40.5-0.4-0.3-0.1
Locomotion in novel chamber post-restriction0.31.04.01.02.01.2-1.21.2-0.2-0.41.1-0.10.30.3
Fecal boli incidents, locomotor time 10.30.83.61.61.90.1-0.0-0.10.00.20.10.31.40.1
Change in fecal boli incidents, locomotor task0.50.53.21.80.50.4-0.30.2-0.2-0.20.3-0.3-1.1-0.4
Time >=10cm from walls, locomotor time 11.11.45.0-2.2-2.1-0.71.1-1.20.71.0-0.90.50.4-0.8
Bouts of movement, locomotor time 11.01.34.42.11.41.0-0.80.7-1.4-1.00.7-1.3-0.8-0.6
Total resting periods, locomotor time 10.91.02.91.71.01.1-0.70.6-1.2-0.80.7-1.1-0.6-0.8
Rest time, locomotor task time 10.10.10.6-0.5-0.30.2-0.1-0.0-0.8-0.30.1-0.4-0.2-0.3
Distance moved, locomotor task time 10.10.41.5-0.2-0.60.0-0.50.6-0.2-0.40.4-0.4-1.01.2
Vertical activity count, locomotor time 10.53.215.33.92.70.9-1.51.5-0.7-1.11.2-0.7-1.21.5
Time >=10cm from walls, locomotor time 20.10.31.0-1.00.10.2-0.40.5-0.5-0.30.4-0.6-0.60.9
Bouts of movement, locomotor time 20.61.94.8-0.40.81.8-1.41.4-1.7-2.21.3-1.2-0.8-1.0
Total resting periods, locomotor time 20.51.84.8-0.60.61.7-1.41.4-1.7-2.21.2-1.3-1.0-0.9
Rest time, locomotor task time 20.81.44.81.72.20.7-0.90.8-1.4-1.30.8-1.0-0.00.7
Distance moved, locomotor task time 20.60.84.2-1.2-2.0-0.70.4-0.20.70.8-0.40.2-1.10.7
Vertical activity count, locomotor time 20.10.21.01.00.10.3-0.30.40.20.20.30.0-0.60.1
Light reinforcement 10.10.41.8-1.2-1.3-0.60.6-0.6-0.2-0.2-0.5-0.3-0.30.1
Light reinforcement 20.20.52.1-1.0-1.4-0.40.6-0.60.20.2-0.60.20.2-0.7
Bone: marrow area0.00.10.4-0.5-0.7-0.20.0-0.0-0.1-0.1-0.2-0.3-0.4-0.1
Bone: maximum diameter1.32.53.80.2-1.0-1.81.8-1.81.81.8-1.81.91.6-0.9
Bone: maximum force0.20.51.21.1-0.0-0.60.5-0.61.01.0-0.60.80.6-0.2
Bone: maximum moment0.30.61.61.30.1-0.70.5-0.51.01.0-0.60.80.6-0.0
Mean time between licks in bursts0.10.62.51.21.60.5-0.70.7-0.1-0.20.7-0.1-0.10.8
Mean num. licks in bursts0.72.02.70.51.61.3-1.61.6-1.5-1.51.5-1.6-1.21.3
Cd content in liver0.70.82.0-0.3-0.4-0.50.6-0.61.41.4-0.71.31.1-0.7
Co content in liver1.01.22.10.40.51.4-1.41.5-1.1-1.11.4-1.0-0.91.0
Cu content in liver0.60.72.8-0.0-0.2-0.30.5-0.61.01.0-0.51.01.7-0.7
Fe content in liver3.24.06.6-2.6-2.0-2.32.4-2.41.61.6-2.31.51.1-1.7
K content in liver0.30.30.5-0.0-0.20.5-0.60.6-0.7-0.70.5-0.7-0.50.6
Mg content in liver0.20.21.30.1-0.50.2-0.50.50.00.00.40.10.21.1
Mn content in liver1.71.910.6-0.3-0.30.3-1.21.2-1.1-1.11.1-1.1-1.43.3
Na content in liver0.00.00.3-0.1-0.5-0.0-0.00.00.0-0.0-0.0-0.0-0.10.2
Rb content in liver0.50.62.5-1.4-1.6-0.50.4-0.40.60.6-0.60.60.2-0.4
Se content in liver0.30.40.9-0.4-0.9-0.90.7-0.70.50.5-0.60.50.30.7
Sr content in liver1.00.83.51.91.30.4-0.60.6-0.7-0.70.6-0.7-0.70.8
Zn content in liver0.30.41.0-0.6-0.1-0.70.6-0.60.60.6-0.60.71.00.0
Bone: minimum diameter0.40.81.41.10.2-0.70.8-0.81.21.2-0.71.10.9-0.3
Time in familiar zone, hab. session 10.20.20.40.70.3-0.60.5-0.60.20.2-0.50.3-0.1-0.2
Time in novel zone, hab. session 10.60.71.2-1.1-0.8-0.80.6-0.61.00.9-0.61.01.00.1
Total zone transitions, hab. session 10.40.61.10.2-0.2-0.90.9-0.91.10.8-0.91.10.6-0.5
Total locomotion distance, hab. session 10.60.84.31.92.10.6-0.50.50.30.00.50.20.2-0.1
Locomotion velocity, hab. session 10.81.15.01.92.21.0-0.80.80.1-0.10.8-0.10.1-0.2
Time in familiar zone, hab. session 21.51.72.7-1.2-0.6-1.21.5-1.51.21.2-1.41.21.4-1.7
Time in novel zone, hab. session 20.10.10.30.50.00.1-0.30.30.10.10.20.1-0.10.5
Total zone transitions, hab. session 20.20.20.80.9-0.2-0.40.2-0.20.70.6-0.20.50.10.6
Total locomotion distance, hab. session 20.91.25.32.31.91.0-1.01.00.1-0.11.0-0.1-0.10.5
Locomotion velocity, hab. session 20.81.15.22.31.80.9-1.01.00.0-0.10.9-0.2-0.30.6
Novel to familiar place preference ratio0.70.91.70.1-0.1-1.31.1-1.11.11.1-1.11.31.0-0.2
Novelty place preference0.60.81.5-0.1-0.2-1.21.0-1.01.01.0-1.01.20.9-0.1
Time in novel zone, NPP test0.91.12.0-0.2-0.2-1.41.2-1.21.21.2-1.21.41.1-0.2
Total zone transitions, NPP test0.20.30.70.6-0.5-0.40.5-0.50.80.7-0.50.60.3-0.6
Total locomotion distance, NPP test1.01.33.21.30.9-0.60.8-0.81.81.6-0.81.51.2-0.9
Locomotion velocity, NPP test0.71.02.41.50.9-0.40.5-0.51.51.4-0.51.20.9-0.8
Intraocular pressure0.81.31.9-1.2-1.0-0.81.2-1.21.41.3-1.01.11.1-1.0
Delta distance traveled before/after self-admin1.01.12.3-0.30.31.5-1.31.4-1.1-1.01.3-0.7-1.10.3
Delta ambulatory time before/after self-admin0.30.61.1-0.10.21.0-0.91.0-0.8-0.61.0-0.3-0.80.6
Parametrial fat weight0.40.96.02.51.70.1-0.40.3-0.0-0.00.40.20.30.8
Pavlov. Cond. lever latency0.40.41.10.80.50.20.1-0.01.01.0-0.00.90.9-0.6
Pavlov. Cond. magazine entry latency0.50.61.0-0.3-0.5-0.70.8-0.81.00.9-0.90.90.6-1.0
Pavlov. Cond. change in total contacts1.01.12.5-0.30.60.8-1.00.9-1.4-1.60.9-1.4-1.40.6
Pavlov. Cond. index score0.10.10.3-0.4-0.5-0.30.1-0.1-0.3-0.4-0.2-0.4-0.50.1
Pavlov. Cond. latency score0.20.30.9-0.4-0.40.1-0.30.2-0.7-0.80.2-0.8-1.00.3
Pavlov. Cond. lever contacts0.20.20.6-0.7-0.2-0.2-0.00.0-0.7-0.80.0-0.7-0.60.4
Pavlov. Cond. magazine entry number0.10.20.30.00.30.3-0.30.4-0.6-0.40.4-0.5-0.10.6
Pavlov. Cond. intertrial magazine entries0.30.41.60.30.5-0.0-0.40.3-0.7-0.70.4-0.7-0.51.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.2-0.2-0.2-0.10.1-0.4-0.50.0-0.4-0.40.5
Pavlov. Cond. response bias0.50.61.0-0.8-0.7-1.00.9-0.90.70.6-1.00.60.6-0.5
Pavlov. Cond. lever latency0.20.31.5-1.2-0.30.2-0.30.3-0.6-0.60.3-0.70.00.2
Pavlov. Cond. magazine entry latency1.92.73.9-0.7-0.8-1.71.8-1.81.92.0-1.81.91.5-1.4
Pavlov. Cond. change in total contacts0.30.61.21.0-0.0-0.40.6-0.61.11.1-0.61.10.6-0.8
Pavlov. Cond. index score0.91.52.60.4-0.3-1.01.2-1.21.61.6-1.21.61.1-1.2
Pavlov. Cond. latency score0.71.12.10.4-0.2-0.91.0-1.01.51.4-1.01.50.9-1.1
Pavlov. Cond. lever contacts0.40.61.31.0-0.1-0.60.8-0.81.01.0-0.71.10.4-0.7
Pavlov. Cond. magazine entry number2.02.54.30.40.71.3-1.61.6-1.9-1.91.7-1.8-1.52.1
Pavlov. Cond. intertrial magazine entries0.81.83.7-0.4-0.31.1-1.21.2-1.8-1.91.2-1.7-1.61.2
Pavlov. Cond. lever-magazine prob. diff.1.01.52.70.3-0.3-1.11.3-1.31.61.6-1.31.61.2-1.1
Pavlov. Cond. response bias0.40.61.20.80.1-0.70.7-0.71.01.0-0.71.10.5-0.6
Time in closed arm before self-admin0.40.71.4-0.2-0.9-1.21.1-1.00.60.6-1.10.50.7-0.6
Time in closed arm after self-admin1.82.16.1-2.5-2.2-0.31.2-1.00.81.0-1.01.00.9-2.2
Time in open arm before self-admin3.94.820.44.54.31.4-1.71.5-1.0-1.41.5-0.70.50.9
Time in open arm after self-admin4.04.57.32.12.71.7-2.42.2-1.7-1.92.2-1.8-1.62.6
Bone: periosteal estimation0.20.50.90.5-0.4-0.80.8-0.81.01.0-0.80.80.7-0.4
Bone: periosteal perimeter0.30.60.80.50.0-0.70.8-0.80.90.8-0.80.90.9-0.7
Bone: post-yield work0.20.31.2-0.9-0.80.30.0-0.0-0.3-0.3-0.0-0.4-0.5-1.1
Progressive ratio test 1 active lever presses0.20.41.3-0.3-0.2-1.10.5-0.50.50.5-0.70.4-0.10.9
Progressive ratio test 1 breakpoint0.20.31.10.20.1-1.00.3-0.30.30.3-0.50.2-0.31.0
Progressive ratio test 1 inactive lever presses0.92.35.4-2.3-1.8-1.71.6-1.61.41.2-1.61.21.1-0.7
Progressive ratio test 2 active lever presses3.14.413.9-3.7-2.4-2.01.9-1.91.91.8-1.91.91.5-1.0
Progressive ratio test 2 breakpoint3.95.016.3-4.0-2.6-2.12.0-2.02.01.9-2.02.01.5-1.0
Progressive ratio test 2 inactive lever presses0.51.76.0-2.4-1.7-1.01.2-1.21.11.0-1.21.10.5-1.1
Incentive Sensitization - Responses3.08.229.7-5.5-3.6-2.22.5-2.52.32.3-2.42.42.1-2.0
Incentive Sensitization - Breakpoint3.78.532.3-5.7-3.7-2.12.5-2.52.32.3-2.42.42.0-2.1
Sum of active levers in priming session hrs 5-61.51.53.3-1.5-0.20.9-1.41.4-1.0-1.01.1-1.3-1.81.0
Progressive ratio0.10.41.40.30.60.7-0.50.5-0.2-0.30.3-1.0-0.5-1.2
Food seeking constrained by brief footshock8.911.214.63.73.13.0-3.23.3-3.7-3.63.2-3.8-3.62.0
Seeking ratio, punishment vs. effort1.12.44.31.41.11.4-1.41.4-2.1-1.91.6-1.3-1.61.7
Retroperitoneal fat weight0.20.91.7-0.0-1.3-0.50.9-1.01.01.0-0.91.00.8-1.3
Reaction time number correct1.24.49.31.4-0.1-2.62.4-2.42.12.2-2.22.23.0-0.1
Reaction time mean minus median0.00.31.8-1.3-0.6-0.40.3-0.4-0.1-0.1-0.5-0.2-0.1-0.7
Reaction time mean minus median AUC0.21.12.0-1.4-1.1-1.11.1-1.20.80.8-1.30.71.0-1.1
Reaction time num false alarms2.23.77.2-0.7-1.6-2.72.5-2.51.71.6-2.51.71.6-0.9
Reaction time num false alarms AUC1.12.65.50.2-1.0-2.32.2-2.21.41.3-2.11.31.4-0.7
Reaction time trials correct on left1.24.49.31.4-0.1-2.62.4-2.42.12.2-2.22.23.0-0.1
Reaction time trials on left1.34.49.31.4-0.1-2.62.4-2.42.12.2-2.22.23.0-0.1
Reaction time mean0.10.30.6-0.8-0.00.6-0.70.7-0.4-0.50.5-0.5-0.7-0.0
Reaction time mean AUC0.10.30.6-0.7-0.10.5-0.60.6-0.5-0.60.4-0.7-0.8-0.1
Median of all reaction times0.30.51.1-0.40.20.9-1.01.0-0.5-0.60.8-0.6-0.90.3
Reaction time omissions0.10.10.60.8-0.4-0.20.1-0.10.20.2-0.00.20.10.4
Reaction time false alarm rate0.20.30.8-0.6-0.9-0.60.6-0.6-0.0-0.1-0.7-0.1-0.4-0.7
Reaction time premature initiation rate0.61.03.6-1.9-0.20.9-1.00.9-0.8-0.80.9-0.8-1.00.6
Reaction time premature initiations0.10.20.8-0.9-0.1-0.40.2-0.30.30.3-0.20.40.70.5
Std. dev. reaction times0.10.21.3-1.1-0.6-0.0-0.00.0-0.3-0.4-0.1-0.4-0.5-0.4
Reaction time trials completed1.34.49.31.4-0.1-2.62.4-2.42.12.2-2.22.23.0-0.1
Reaction time trials AUC1.55.19.91.4-0.2-2.92.6-2.62.32.3-2.42.43.1-0.0
Run reversals in cocaine runway, females0.80.94.5-1.2-2.10.10.6-0.60.60.7-0.40.50.4-1.3
Run reversals in cocaine runway, males0.20.20.5-0.10.6-0.3-0.0-0.10.70.6-0.00.60.50.7
Latency to leave start box in cocaine runway1.52.04.7-2.2-1.4-1.11.3-1.41.21.5-1.41.40.9-1.5
Latency to leave start box in cocaine runway, F0.60.71.5-0.5-0.3-0.90.9-0.90.70.8-0.91.21.2-0.5
Latency to leave start box in cocaine runway, M2.82.611.0-3.3-2.4-0.91.1-1.31.11.3-1.30.80.0-1.8
Std. dev. time between licks in bursts0.00.10.30.50.0-0.20.1-0.1-0.3-0.4-0.1-0.3-0.60.2
Total sessions with >9 infusions2.43.014.0-3.7-2.3-1.81.1-1.11.41.2-1.41.10.80.5
Short access day 1 total inactive lever presses2.75.329.7-5.5-3.5-1.21.3-1.31.61.6-1.41.40.8-1.2
Short access day 10 total inactive lever presses0.00.20.70.7-0.10.9-0.30.3-0.2-0.30.5-0.10.4-0.8
Short access day 1 total infusions0.91.87.5-2.7-2.0-1.30.8-0.81.11.0-1.01.00.60.4
Short access day 10 total infusions0.91.43.5-1.2-1.1-1.91.3-1.21.01.0-1.40.91.10.5
Short access total infusions0.81.12.8-1.7-1.3-1.40.9-0.90.90.8-1.00.80.60.5
Short access day 1 locomotion1.93.111.2-3.3-2.0-1.81.3-1.31.61.5-1.51.51.50.2
Short access day 10 total locomotion0.31.33.61.81.90.3-0.90.9-0.9-1.00.7-1.2-0.11.4
Short access total locomotion0.40.63.6-0.30.6-0.3-0.60.6-0.5-0.60.3-0.8-0.41.9
One hour access (0.3 mA shock)4.45.231.9-5.6-3.7-1.11.2-1.31.21.0-1.41.30.1-1.4
Compulsive drug intake1.21.712.8-3.6-1.9-0.4-0.00.00.1-0.0-0.20.2-1.30.5
One hour access (shock baseline)2.15.620.9-4.6-3.4-1.92.0-2.01.81.8-2.01.71.3-1.4
Social response proportion0.81.02.3-0.4-1.2-1.51.3-1.10.80.6-1.30.90.6-0.3
Social responses1.01.35.5-2.3-2.1-1.20.9-0.90.10.0-1.00.3-0.3-0.2
Social time1.11.83.20.91.31.8-1.51.5-1.5-1.51.4-1.3-1.2-0.5
Soleus weight1.54.58.10.3-0.9-1.42.1-2.12.52.4-2.02.52.6-2.8
Bone: stiffness0.91.72.4-0.1-0.7-1.41.4-1.51.51.5-1.51.51.4-1.1
Tibialis anterior weight3.211.116.50.5-1.1-3.53.6-3.64.14.0-3.64.04.0-2.2
Time to tail flick, vehicle, before self-admin0.60.73.71.80.4-0.70.10.00.10.1-0.0-0.4-0.41.9
Time to tail flick, vehicle, after self-admin2.14.310.8-3.3-3.2-1.31.9-2.01.61.6-1.81.50.8-2.3
Time to tail flick, test, before self-admin4.04.67.02.62.41.6-2.12.1-2.2-2.02.1-2.4-1.52.3
Time to tail flick, test, after self-admin0.60.61.60.60.40.4-0.60.7-1.2-1.10.5-1.2-0.70.3
Delta time to tail flick, vehicle, before/after SA1.11.12.9-1.7-1.3-0.51.0-1.10.50.7-0.90.90.9-1.5
Delta time to tail flick, test, before/after SA1.21.52.1-1.3-1.4-1.31.4-1.41.01.0-1.41.00.9-1.1
Tibia length0.10.20.8-0.3-0.9-0.40.2-0.20.10.2-0.20.0-0.10.7
Ambulatory time before self-admin0.20.75.32.31.50.0-0.0-0.00.0-0.4-0.0-0.30.6-0.2
Ambulatory time after self-admin0.81.33.51.91.51.0-1.11.1-0.9-1.11.0-1.0-0.70.5
Bone: tissue strength1.31.43.61.91.61.0-1.01.0-1.0-1.01.1-1.0-0.90.9
Total heroin consumption0.30.41.00.60.60.2-0.50.5-0.6-0.60.3-1.0-1.00.1
Bone: trabecular number0.00.10.40.60.20.00.2-0.2-0.2-0.2-0.0-0.2-0.3-0.2
Bone: trabecular spacing0.00.00.10.00.4-0.0-0.10.10.20.20.00.30.30.2
Bone: trabecular thickness0.81.11.60.4-0.4-1.31.3-1.21.31.3-1.11.21.1-0.2
Bone: trabecular tissue density0.81.44.7-0.30.5-0.80.8-0.81.61.5-0.81.52.2-0.5
Water consumed over 24 hours0.50.92.80.50.40.6-1.01.0-0.9-0.81.0-0.9-1.21.7
Number of responses in last shaping day3.44.415.2-3.9-2.6-2.01.7-1.72.02.0-1.91.71.3-0.5