Zfp541

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA XM_063288451.1 0.02 0.02 3.5e-04 0.02 0.01 0.02 0.01 3.2e-04 2.4e-03 1.2e-03 5.1e-03
2 NAcc alternative polyA XM_063288451.1 0.02 0.02 4.4e-04 0.02 0.01 0.01 0.01 3.9e-04 3.2e-03 1.9e-03 7.8e-03
3 Liver gene expression Zfp541 0.56 0.16 4.5e-05 -0 0.04 0.03 0 6.4e-01 9.3e-06 9.8e-05 2.0e-01
4 Liver alternative polyA XM_063288451.1 0.05 0.04 1.0e-04 0.02 0.03 0.02 0.03 1.6e-03 3.6e-04 1.2e-03 5.9e-04
5 Liver alternative polyA XM_063288451.1 0.05 0.04 1.0e-04 0.02 0.03 0.03 0.03 1.6e-03 3.5e-04 4.1e-04 4.9e-04
6 Liver alternative polyA NM_001107458.2 0.04 0.03 1.1e-04 0.02 0.03 0.02 0.02 2.9e-03 4.0e-04 1.8e-03 9.6e-04
7 Liver alternative polyA NM_001107458.2 0.04 0.03 1.1e-04 0.02 0.03 0.02 0.02 3.0e-03 4.1e-04 1.5e-03 8.9e-04
8 Adipose gene expression Zfp541 0.06 0.04 7.6e-08 0.05 0.06 0.05 0.05 1.4e-06 3.4e-07 4.3e-06 1.2e-06
9 Adipose alternative polyA NM_001107458.2 0.03 0.03 1.2e-03 0.02 0.02 0.01 0.02 2.4e-03 4.2e-03 1.4e-02 5.2e-03
10 Adipose alternative polyA NM_001107458.2 0.03 0.03 1.2e-03 0.02 0.02 0.01 0.02 2.4e-03 4.1e-03 1.4e-02 5.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.30.63.8-0.2-0.2-1.9-0.4-0.40.50.50.50.70.7
Area under the delay curve0.60.61.7-1.3-1.30.6-0.7-0.70.60.60.60.50.5
BMI with tail1.24.28.01.91.92.81.81.8-1.9-1.9-1.9-2.2-2.2
BMI without tail2.16.38.72.22.23.02.42.4-2.4-2.4-2.5-2.8-2.8
Body weight2.310.211.42.92.92.53.43.4-3.3-3.3-3.3-3.4-3.4
Weight adjusted by age0.60.81.20.70.70.81.11.1-1.0-1.0-1.0-0.8-0.8
Bone surface0.30.61.60.70.7-1.30.80.8-0.7-0.7-0.7-0.3-0.3
Bone volume0.30.54.30.30.3-2.10.40.4-0.3-0.3-0.20.10.1
Breakpoint value in progressive ratio session1.51.72.6-1.0-1.00.2-1.6-1.61.61.51.51.31.3
Number of licking bursts1.82.94.52.12.11.41.61.6-1.6-1.6-1.6-1.6-1.6
Context. condit. distance diff. score0.00.00.0-0.1-0.10.20.20.2-0.2-0.2-0.2-0.1-0.1
Locomotion velocity, session 10.70.71.2-0.9-0.9-1.1-0.8-0.80.80.80.80.80.8
Locomotion distance, session 10.10.10.7-0.2-0.2-0.80.10.1-0.0-0.00.10.50.5
Locomotion velocity, session 21.21.41.81.31.30.41.21.2-1.2-1.2-1.2-1.2-1.2
Locomotion distance, session 20.91.21.90.90.90.61.41.4-1.3-1.3-1.2-1.0-1.0
Locomotion velocity, session 30.10.10.10.20.20.20.40.4-0.4-0.3-0.3-0.3-0.3
Locomotion distance, session 30.50.52.1-1.5-1.5-0.3-0.2-0.20.30.30.40.50.5
Stereotopy head waving bouts, day 30.30.31.11.01.00.30.30.3-0.3-0.3-0.4-0.5-0.5
Stereotopy head waving duration, day 30.20.21.11.11.10.20.00.0-0.1-0.1-0.1-0.2-0.2
Locomotion velocity, session 71.11.21.6-1.1-1.1-1.1-1.0-1.01.11.11.11.21.2
Locomotion distance, session 70.10.10.7-0.2-0.2-0.8-0.2-0.20.20.20.20.30.3
Stereotopy head waving bouts, day 70.40.51.00.50.51.00.70.7-0.7-0.7-0.7-0.7-0.7
Stereotopy head waving duration, day 70.40.40.50.60.60.70.70.7-0.7-0.7-0.7-0.7-0.7
Locomotion velocity, session 80.10.20.3-0.4-0.4-0.6-0.3-0.30.30.30.30.50.5
Locomotion distance, session 80.10.20.40.10.10.40.60.6-0.6-0.5-0.5-0.3-0.3
Degree of sensitization distance0.20.20.91.01.0-0.50.10.1-0.1-0.1-0.1-0.1-0.1
Degree of sensitization stereotypy0.91.01.90.50.51.41.11.1-1.1-1.1-1.0-1.0-1.0
Conditioned locomotion0.10.10.7-0.2-0.20.90.20.2-0.2-0.2-0.2-0.4-0.4
Cocaine response after cond. corrected0.10.10.40.50.50.6-0.0-0.0-0.1-0.1-0.1-0.2-0.2
Cocaine response after cond. not corrected0.60.71.21.11.10.80.70.7-0.7-0.7-0.8-0.7-0.7
Cocaine response before conditioning2.32.84.01.71.70.82.02.0-1.9-1.9-1.8-1.3-1.3
Saline control response1.01.31.91.01.00.41.41.4-1.3-1.3-1.3-0.9-0.9
Bone: connectivity density0.10.11.00.10.1-1.0-0.1-0.10.10.10.20.30.3
Bone: cortical apparent density0.20.30.5-0.7-0.70.5-0.6-0.60.60.60.50.50.5
Bone: cortical area1.01.52.21.51.5-0.31.31.3-1.2-1.2-1.2-1.1-1.1
Bone: cortical porosity0.10.10.30.50.50.20.10.1-0.1-0.1-0.1-0.3-0.3
Bone: cortical porosity0.40.50.60.80.80.70.60.6-0.6-0.6-0.6-0.8-0.8
Bone: cortical thickness0.10.20.60.80.8-0.60.20.2-0.2-0.2-0.2-0.3-0.3
Bone: cortical thickness0.30.31.00.60.6-1.00.40.4-0.5-0.5-0.5-0.6-0.6
Bone: cortical tissue density0.30.40.7-0.9-0.90.4-0.7-0.70.60.60.60.60.6
Condit. Reinf. active minus inactive responses1.01.13.61.01.01.90.90.9-0.9-0.9-0.9-1.0-1.0
Condit. Reinf. active-inactive response ratio1.41.54.71.01.02.21.01.0-1.0-1.0-1.1-1.1-1.1
Condit. Reinf. active responses0.50.61.90.60.61.40.70.7-0.7-0.7-0.7-0.7-0.7
Condit. Reinf. inactive responses0.40.41.6-0.7-0.7-1.2-0.4-0.40.50.50.50.60.6
Incentive salience index mean0.70.92.00.90.91.40.90.9-0.9-0.9-0.9-0.9-0.9
Condit. Reinf. lever presses0.20.30.40.50.50.50.60.6-0.6-0.6-0.6-0.6-0.6
Condit. Reinf. active minus inactive responses0.10.10.4-0.3-0.3-0.60.20.2-0.1-0.1-0.00.10.1
Condit. Reinf. active-inactive response ratio0.20.21.7-0.3-0.3-1.30.20.2-0.1-0.1-0.00.10.1
Condit. Reinf. active responses0.10.10.3-0.5-0.5-0.40.20.2-0.1-0.10.00.20.2
Condit. Reinf. inactive responses0.10.10.3-0.5-0.50.2-0.2-0.20.30.30.30.40.4
Condit. Reinf. lever presses0.60.82.10.50.51.51.01.0-0.9-0.9-0.9-0.8-0.8
Condit. Reinf. lever reinforcers received0.10.10.3-0.5-0.5-0.50.30.3-0.2-0.2-0.10.20.2
Conditioned reinforcement - actives1.93.35.82.42.41.61.61.6-1.6-1.6-1.6-1.7-1.7
Conditioned reinforcement - inactives0.71.13.21.81.8-0.10.80.8-0.9-0.8-0.8-0.5-0.5
Conditioned locomotion1.11.43.82.02.00.80.90.9-0.9-0.9-0.9-1.0-1.0
Patch foraging indifference point 0 sec0.10.10.40.60.60.60.10.1-0.1-0.1-0.10.10.1
Patch foraging indifference point AUC3.44.95.81.91.92.42.32.3-2.3-2.3-2.3-2.2-2.2
Delay disc. indifference point, 0s delay0.30.30.9-1.0-1.0-0.1-0.4-0.40.40.40.50.50.5
Delay disc. indifference point, 16s delay0.30.40.5-0.7-0.70.6-0.7-0.70.60.60.60.40.4
Delay disc. indifference point, 2s delay0.80.92.7-1.6-1.60.4-0.8-0.80.80.80.70.70.7
Delay disc. indifference point, 24s delay0.30.32.20.50.51.50.20.2-0.2-0.2-0.3-0.3-0.3
Delay disc. indifference point, 4s delay0.10.10.3-0.2-0.20.60.40.4-0.4-0.4-0.4-0.4-0.4
Delay disc. indifference point, 8s delay1.11.32.6-1.6-1.60.1-1.1-1.11.11.11.00.90.9
Indifference point function ln k2.64.511.2-1.7-1.7-3.3-1.8-1.81.91.91.92.32.3
Indifference point function log k2.64.511.2-1.7-1.7-3.3-1.8-1.81.91.91.92.32.3
Patch foraging total patch changes 0 sec0.10.10.60.80.80.20.20.2-0.2-0.2-0.20.00.0
Patch foraging total patch changes 12 sec1.62.13.01.41.41.71.41.4-1.4-1.4-1.4-1.4-1.4
Patch foraging total patch changes 18 sec1.31.92.21.41.41.41.51.5-1.5-1.5-1.4-1.2-1.2
Patch foraging total patch changes 24 sec1.42.42.71.61.61.71.61.6-1.6-1.6-1.6-1.4-1.4
Patch foraging total patch changes 6 sec1.21.83.51.41.41.91.21.2-1.3-1.3-1.3-1.1-1.1
Patch foraging time to switch 0 sec1.12.23.3-1.4-1.4-0.4-1.8-1.81.71.71.61.21.2
Patch foraging water rate 0 sec1.12.43.21.81.80.41.71.7-1.7-1.7-1.6-1.3-1.3
Patch foraging water rate 12 sec0.10.20.90.30.3-1.00.10.10.00.00.10.40.4
Patch foraging water rate 18 sec0.10.21.20.20.2-1.1-0.1-0.10.20.20.20.60.6
Patch foraging water rate 24 sec0.20.31.3-0.1-0.1-1.1-0.3-0.30.40.40.40.70.7
Patch foraging water rate 6 sec1.62.33.41.31.30.71.81.8-1.7-1.7-1.6-1.4-1.4
Seeking ratio, delayed vs. immediate footshock2.42.94.4-2.0-2.0-2.1-1.5-1.51.61.61.61.61.6
Distance traveled before self-admin0.10.10.3-0.3-0.3-0.50.30.3-0.2-0.2-0.10.10.1
Distance traveled after self-admin0.60.81.1-0.9-0.9-1.0-0.8-0.80.80.80.81.01.0
Extensor digitorum longus weight1.56.08.52.92.9-0.82.62.6-2.6-2.6-2.6-2.2-2.2
Bone: elastic displacement2.02.34.2-0.9-0.9-2.0-1.6-1.61.51.51.51.61.6
Bone: elastic work0.20.31.80.40.4-1.3-0.2-0.20.20.20.30.50.5
Bone: endosteal estimation0.10.10.3-0.2-0.2-0.60.50.5-0.4-0.4-0.3-0.0-0.0
Bone: endosteal perimeter0.00.10.20.20.20.30.40.4-0.4-0.4-0.3-0.2-0.2
Epididymis fat weight0.31.11.9-0.9-0.9-1.4-1.1-1.11.11.11.10.90.9
Delta time in closed arm before/after self-admin0.30.30.8-0.9-0.9-0.6-0.3-0.30.30.30.30.10.1
Delta time in open arm before/after self-admin0.30.30.80.90.90.50.50.5-0.5-0.5-0.4-0.2-0.2
Diff in mean of infusions in LGA sessions1.11.32.5-1.6-1.6-0.2-1.1-1.11.11.11.11.01.0
Delay discount exponential model param0.40.51.31.11.1-0.60.50.5-0.5-0.5-0.5-0.4-0.4
Extinction: sum of active levers before priming0.00.00.10.20.2-0.2-0.1-0.10.10.10.10.30.3
Active lever presses in extinction session 62.22.27.30.50.52.71.31.3-1.4-1.4-1.4-1.6-1.6
Bone: final force0.81.31.81.11.1-0.21.31.3-1.3-1.3-1.2-1.0-1.0
Bone: final moment0.91.52.01.21.2-0.71.41.4-1.3-1.3-1.2-1.1-1.1
Food consumed during 24 hour testing period2.93.94.2-2.0-2.0-1.5-2.0-2.02.02.02.12.02.0
Glucose1.72.73.3-1.7-1.7-0.5-1.8-1.81.81.81.71.51.5
Heart weight0.71.12.81.71.70.70.90.9-0.9-0.9-0.9-0.8-0.8
Delay discount hyperbolic model param0.40.41.21.11.1-0.70.50.4-0.4-0.4-0.4-0.3-0.3
Intermittent access intake day 1-15 change0.10.20.30.30.30.20.50.5-0.5-0.5-0.5-0.6-0.6
Intermittent access intake escalation0.20.50.70.50.50.50.70.7-0.7-0.7-0.7-0.8-0.8
Intermittent access intake escalation 20.10.10.4-0.6-0.6-0.6-0.1-0.10.10.10.10.10.1
Intermitt. access day 1 inactive lever presses0.10.40.80.80.80.90.40.4-0.5-0.5-0.5-0.5-0.5
Intermitt. access day 15 inactive lever presses0.30.70.90.80.80.50.90.9-0.9-0.9-0.9-0.8-0.8
Intermitt. access escalation Index0.20.32.6-0.2-0.21.6-0.0-0.0-0.0-0.0-0.1-0.4-0.4
Intermittent access day 1 total infusions1.01.73.61.91.91.11.11.1-1.1-1.1-1.1-1.1-1.1
Intermittent access day 15 total infusions0.60.91.51.21.21.10.70.7-0.7-0.7-0.8-0.9-0.9
Intermittent access terminal intake (last 3 days)0.30.41.21.11.10.50.40.4-0.5-0.5-0.5-0.6-0.6
Intermittent access total infusions1.21.42.91.71.71.11.01.0-1.0-1.0-1.0-1.1-1.1
Intermittent access day 1 locomotion0.20.31.31.21.2-0.6-0.1-0.10.00.00.00.20.2
Intermittent access day 15 total locomotion0.10.10.50.70.7-0.5-0.2-0.20.20.20.20.20.2
Intermittent access total locomotion0.50.62.41.51.5-0.70.30.3-0.3-0.3-0.3-0.1-0.1
Intermittent access standard deviation0.10.20.5-0.7-0.70.4-0.4-0.40.40.40.3-0.0-0.0
Left kidney weight4.822.227.14.94.92.45.25.2-5.1-5.1-4.9-4.4-4.4
Right kidney weight3.717.021.04.34.31.64.64.6-4.5-4.5-4.4-3.9-3.9
Cocaine induced anxiety0.40.52.4-0.2-0.2-1.5-0.5-0.50.50.50.60.80.8
Post-drug Anxiety0.30.31.3-0.3-0.3-1.1-0.4-0.40.50.50.50.70.7
Baseline Anxiety0.70.91.0-1.0-1.0-0.6-1.0-1.01.01.01.00.90.9
Tail length1.35.26.72.02.01.32.62.6-2.5-2.5-2.4-2.3-2.3
Length with tail0.83.34.51.71.70.32.12.1-2.0-2.0-2.0-1.8-1.8
Length without tail0.41.31.71.31.3-0.41.31.3-1.2-1.2-1.2-1.0-1.0
Times rat made contact with spout0.70.80.9-0.7-0.7-0.9-1.0-1.00.90.90.90.80.8
Lifetime Intake1.72.13.71.91.91.61.21.2-1.3-1.3-1.3-1.3-1.3
Liver weight, left4.87.99.12.42.42.33.03.0-3.0-3.0-3.0-3.0-3.0
Liver weight, right1.93.34.21.61.62.01.91.9-1.9-1.9-1.9-1.8-1.8
Locomotor activity1.72.63.11.81.81.71.51.5-1.5-1.5-1.6-1.7-1.7
Locomotor testing distance1.32.33.51.91.91.21.41.4-1.4-1.4-1.5-1.5-1.5
Locomotor testing rearing4.69.310.33.23.22.53.13.1-3.1-3.1-3.1-3.1-3.1
Locomotion in novel chamber2.53.23.7-1.2-1.2-1.9-1.9-1.91.91.91.91.91.9
Locomotion in novel chamber post-restriction0.61.01.5-1.2-1.2-0.5-1.0-1.01.01.01.00.90.9
Fecal boli incidents, locomotor time 10.10.10.60.60.6-0.8-0.1-0.10.10.10.10.10.1
Change in fecal boli incidents, locomotor task0.70.71.4-1.2-1.2-0.3-0.9-0.90.80.80.80.50.5
Time >=10cm from walls, locomotor time 10.00.00.10.20.20.2-0.2-0.20.20.20.10.10.1
Bouts of movement, locomotor time 11.51.73.8-2.0-2.0-0.8-1.1-1.11.21.21.21.11.1
Total resting periods, locomotor time 12.83.25.0-2.2-2.2-1.5-1.7-1.71.71.71.71.61.6
Rest time, locomotor task time 10.70.93.2-0.8-0.8-1.8-0.7-0.70.70.70.70.90.9
Distance moved, locomotor task time 11.01.53.71.31.31.91.01.0-1.0-1.0-1.1-1.2-1.2
Vertical activity count, locomotor time 10.20.41.80.40.41.30.40.4-0.4-0.4-0.5-0.7-0.7
Time >=10cm from walls, locomotor time 20.00.10.2-0.0-0.0-0.30.10.1-0.1-0.1-0.1-0.5-0.5
Bouts of movement, locomotor time 21.82.94.4-2.1-2.1-0.4-1.7-1.71.71.71.71.61.6
Total resting periods, locomotor time 22.03.54.6-2.2-2.2-0.7-1.9-1.91.91.91.91.91.9
Rest time, locomotor task time 21.51.93.3-0.6-0.6-1.8-1.3-1.31.41.41.41.81.8
Distance moved, locomotor task time 21.92.23.41.21.21.21.51.5-1.5-1.5-1.5-1.8-1.8
Vertical activity count, locomotor time 20.71.01.70.20.21.21.01.0-1.0-1.0-1.0-1.3-1.3
Light reinforcement 10.30.81.31.21.20.70.90.9-0.9-0.9-0.9-0.8-0.8
Light reinforcement 21.11.72.31.51.51.21.21.2-1.2-1.2-1.2-1.4-1.4
Bone: marrow area0.10.20.4-0.1-0.1-0.40.60.6-0.5-0.5-0.4-0.2-0.2
Bone: maximum diameter2.95.45.92.42.42.02.42.4-2.4-2.4-2.3-2.2-2.2
Bone: maximum force0.40.71.00.80.8-0.31.01.0-0.9-0.9-0.9-0.6-0.6
Bone: maximum moment0.40.81.10.90.9-0.91.01.0-0.9-0.9-0.9-0.6-0.6
Mean time between licks in bursts0.00.10.20.30.30.30.10.1-0.1-0.1-0.1-0.4-0.4
Mean num. licks in bursts3.45.26.9-2.6-2.6-2.2-2.2-2.22.22.22.22.22.2
Cd content in liver0.70.82.5-0.6-0.6-1.6-0.7-0.70.80.80.80.90.9
Co content in liver0.70.81.1-1.1-1.1-0.3-0.9-0.90.90.90.90.90.9
Cu content in liver0.50.60.80.60.6-0.70.90.9-0.9-0.9-0.8-0.7-0.7
Fe content in liver3.03.74.21.71.71.92.12.1-2.0-2.0-2.0-1.9-1.9
K content in liver0.80.71.10.60.60.11.11.1-1.0-1.0-1.0-0.8-0.8
Mg content in liver1.71.82.01.01.01.41.41.4-1.4-1.4-1.4-1.4-1.4
Mn content in liver0.60.70.90.50.50.80.90.9-0.9-0.9-0.9-1.0-1.0
Na content in liver0.10.10.5-0.2-0.2-0.70.20.2-0.2-0.2-0.2-0.2-0.2
Rb content in liver0.30.30.50.20.2-0.60.70.7-0.7-0.7-0.6-0.5-0.5
Se content in liver8.29.714.92.52.53.93.03.0-3.1-3.1-3.1-3.3-3.3
Sr content in liver0.20.20.40.50.50.6-0.5-0.50.40.40.30.10.1
Zn content in liver2.42.74.12.02.01.11.51.5-1.6-1.6-1.6-1.6-1.6
Bone: minimum diameter0.30.62.00.40.4-1.40.90.9-0.8-0.8-0.7-0.5-0.5
Time in familiar zone, hab. session 10.50.43.10.70.7-1.8-0.0-0.10.10.10.10.40.4
Time in novel zone, hab. session 11.51.55.20.50.52.31.11.1-1.1-1.1-1.2-1.3-1.3
Total zone transitions, hab. session 10.10.11.00.10.1-1.00.20.2-0.2-0.2-0.10.10.1
Total locomotion distance, hab. session 10.40.51.0-0.6-0.6-1.0-0.6-0.60.70.70.70.80.8
Locomotion velocity, hab. session 11.01.41.8-1.1-1.1-1.4-1.1-1.11.21.21.21.31.3
Time in familiar zone, hab. session 20.10.10.60.60.6-0.8-0.2-0.20.20.20.20.10.1
Time in novel zone, hab. session 20.30.31.5-0.5-0.51.20.40.4-0.4-0.4-0.4-0.3-0.3
Total zone transitions, hab. session 20.30.40.70.70.7-0.40.90.9-0.8-0.8-0.7-0.3-0.3
Total locomotion distance, hab. session 20.40.60.7-0.8-0.8-0.8-0.7-0.70.70.70.70.80.8
Locomotion velocity, hab. session 20.20.30.4-0.6-0.6-0.7-0.5-0.50.50.50.50.60.6
Novel to familiar place preference ratio0.60.60.80.60.60.10.90.9-0.9-0.9-0.9-0.8-0.8
Novelty place preference0.50.50.70.60.6-0.00.80.8-0.8-0.8-0.8-0.7-0.7
Time in novel zone, NPP test0.50.50.70.60.60.00.80.8-0.8-0.8-0.8-0.7-0.7
Total zone transitions, NPP test0.20.30.40.60.60.30.60.6-0.6-0.6-0.6-0.3-0.3
Total locomotion distance, NPP test0.10.10.10.30.30.20.30.3-0.3-0.3-0.3-0.1-0.1
Locomotion velocity, NPP test0.10.10.10.30.30.00.40.4-0.3-0.3-0.3-0.1-0.1
Intraocular pressure0.20.30.5-0.7-0.7-0.7-0.4-0.40.50.50.50.40.4
Delta distance traveled before/after self-admin0.40.40.6-0.6-0.60.1-0.8-0.80.80.80.70.60.6
Delta ambulatory time before/after self-admin0.30.30.5-0.2-0.2-0.2-0.7-0.70.70.70.60.60.6
Parametrial fat weight0.20.60.9-0.5-0.5-0.5-1.0-0.90.90.90.80.70.7
Pavlov. Cond. lever latency0.81.01.3-0.9-0.9-0.8-1.0-1.01.11.11.11.11.1
Pavlov. Cond. magazine entry latency0.91.21.80.90.91.30.90.9-1.0-1.0-1.0-1.4-1.4
Pavlov. Cond. change in total contacts0.10.10.2-0.5-0.50.5-0.3-0.30.30.30.2-0.0-0.0
Pavlov. Cond. index score1.11.42.21.01.01.21.11.1-1.2-1.2-1.2-1.5-1.5
Pavlov. Cond. latency score0.60.71.20.70.70.90.80.8-0.8-0.8-0.8-1.1-1.1
Pavlov. Cond. lever contacts0.70.81.00.80.80.80.90.9-0.9-0.9-0.9-1.0-1.0
Pavlov. Cond. magazine entry number0.70.81.5-0.5-0.5-1.0-0.8-0.80.90.90.91.21.2
Pavlov. Cond. intertrial magazine entries0.30.41.2-0.0-0.0-1.1-0.5-0.50.50.50.60.90.9
Pavlov. Cond. lever-magazine prob. diff.1.21.52.31.01.01.21.21.2-1.2-1.2-1.2-1.5-1.5
Pavlov. Cond. response bias2.02.53.51.31.31.51.61.6-1.6-1.6-1.6-1.9-1.9
Pavlov. Cond. lever latency0.20.31.1-0.3-0.3-1.1-0.5-0.50.50.50.50.50.5
Pavlov. Cond. magazine entry latency0.20.32.30.20.21.50.20.2-0.2-0.2-0.2-0.4-0.4
Pavlov. Cond. change in total contacts0.20.30.7-0.8-0.8-0.4-0.4-0.40.40.40.50.50.5
Pavlov. Cond. index score0.10.21.10.10.11.10.30.3-0.3-0.3-0.3-0.3-0.3
Pavlov. Cond. latency score0.10.10.8-0.0-0.00.90.00.0-0.0-0.00.0-0.0-0.0
Pavlov. Cond. lever contacts0.40.61.70.50.51.30.80.8-0.8-0.8-0.7-0.7-0.7
Pavlov. Cond. magazine entry number0.10.10.80.20.2-0.90.30.3-0.3-0.3-0.3-0.2-0.2
Pavlov. Cond. intertrial magazine entries0.10.21.6-0.2-0.2-1.30.10.1-0.1-0.1-0.10.30.3
Pavlov. Cond. lever-magazine prob. diff.0.20.31.30.30.31.20.50.5-0.4-0.4-0.4-0.4-0.4
Pavlov. Cond. response bias0.20.31.10.10.11.10.60.6-0.6-0.6-0.5-0.5-0.5
Time in closed arm before self-admin0.20.30.80.90.90.00.40.4-0.4-0.4-0.5-0.4-0.4
Time in closed arm after self-admin0.50.51.2-1.1-1.1-0.5-0.6-0.60.60.60.60.40.4
Time in open arm before self-admin0.20.20.3-0.6-0.60.2-0.4-0.40.40.40.40.30.3
Time in open arm after self-admin0.10.10.30.50.50.2-0.1-0.10.10.10.10.20.2
Bone: periosteal estimation0.40.81.30.70.7-0.41.11.1-1.0-1.0-0.9-0.7-0.7
Bone: periosteal perimeter0.40.71.00.90.9-0.11.01.0-0.9-0.9-0.8-0.7-0.7
Bone: post-yield work0.10.10.3-0.6-0.6-0.4-0.1-0.10.20.20.20.50.5
Progressive ratio test 1 active lever presses1.21.43.41.81.80.31.11.1-1.1-1.1-1.1-0.9-0.9
Progressive ratio test 1 breakpoint1.01.23.01.71.70.31.01.0-1.0-1.0-1.0-0.8-0.8
Progressive ratio test 1 inactive lever presses1.52.23.11.71.71.11.61.5-1.5-1.5-1.5-1.3-1.3
Progressive ratio test 2 active lever presses2.73.26.32.52.51.71.41.4-1.5-1.5-1.5-1.6-1.6
Progressive ratio test 2 breakpoint3.03.46.72.62.61.71.51.5-1.6-1.6-1.6-1.7-1.7
Progressive ratio test 2 inactive lever presses1.11.82.81.71.70.61.41.4-1.4-1.4-1.4-1.2-1.2
Incentive Sensitization - Responses1.62.25.02.22.21.31.11.1-1.2-1.2-1.2-1.3-1.3
Incentive Sensitization - Breakpoint1.72.35.02.22.21.41.21.2-1.2-1.2-1.2-1.3-1.3
Sum of active levers in priming session hrs 5-60.50.50.7-0.8-0.8-0.1-0.7-0.70.70.70.70.50.5
Progressive ratio0.10.20.7-0.8-0.80.1-0.3-0.30.40.40.40.30.3
Food seeking constrained by brief footshock3.34.07.5-2.0-2.0-2.7-1.7-1.71.81.81.92.12.1
Seeking ratio, punishment vs. effort0.71.03.2-0.7-0.7-1.8-0.8-0.80.80.80.81.11.1
Retroperitoneal fat weight0.20.71.5-0.5-0.5-0.2-1.2-1.21.11.10.90.30.3
Reaction time number correct1.42.74.42.12.11.11.61.6-1.6-1.6-1.6-1.5-1.5
Reaction time mean minus median0.41.11.6-1.2-1.2-0.7-1.0-1.01.01.01.01.01.0
Reaction time mean minus median AUC0.10.20.4-0.5-0.5-0.6-0.3-0.30.40.40.40.50.5
Reaction time num false alarms5.27.37.82.72.72.82.62.6-2.7-2.7-2.7-2.8-2.8
Reaction time num false alarms AUC3.75.86.12.52.52.42.42.4-2.4-2.4-2.4-2.4-2.4
Reaction time trials correct on left1.42.74.42.12.11.11.61.6-1.6-1.6-1.6-1.5-1.5
Reaction time trials on left1.52.84.52.12.11.11.61.6-1.6-1.6-1.6-1.5-1.5
Reaction time mean1.62.53.0-1.7-1.7-1.1-1.5-1.51.61.61.61.71.7
Reaction time mean AUC1.32.22.3-1.5-1.5-1.3-1.5-1.51.51.51.41.51.5
Median of all reaction times1.31.92.3-1.5-1.5-0.8-1.4-1.41.41.41.41.51.5
Reaction time omissions0.10.10.70.60.60.80.10.1-0.1-0.1-0.10.10.1
Reaction time false alarm rate0.81.12.60.80.81.61.01.0-1.0-1.0-1.0-1.1-1.1
Reaction time premature initiation rate1.62.22.9-1.0-1.0-1.4-1.6-1.61.61.61.61.71.7
Reaction time premature initiations0.30.61.40.10.1-1.2-0.8-0.80.70.70.70.90.9
Std. dev. reaction times0.81.41.5-1.2-1.2-1.0-1.2-1.21.21.21.21.21.2
Reaction time trials completed1.52.84.52.12.11.11.61.6-1.6-1.6-1.6-1.5-1.5
Reaction time trials AUC1.93.55.82.42.41.31.81.8-1.8-1.8-1.8-1.7-1.7
Run reversals in cocaine runway, females1.51.52.1-0.2-0.2-1.2-1.5-1.51.41.41.41.31.3
Run reversals in cocaine runway, males0.50.50.60.30.30.70.80.8-0.8-0.8-0.8-0.8-0.8
Latency to leave start box in cocaine runway0.40.40.8-0.3-0.3-0.9-0.7-0.70.70.70.70.60.6
Latency to leave start box in cocaine runway, F0.10.20.30.10.1-0.6-0.5-0.50.50.50.40.30.3
Latency to leave start box in cocaine runway, M0.00.00.1-0.2-0.2-0.30.10.1-0.0-0.00.00.10.1
Std. dev. time between licks in bursts0.60.82.00.40.41.40.90.9-0.9-0.9-0.9-1.0-1.0
Total sessions with >9 infusions2.02.43.92.02.01.11.51.5-1.5-1.5-1.5-1.3-1.3
Short access day 1 total inactive lever presses2.12.83.51.91.91.41.71.7-1.6-1.6-1.6-1.6-1.6
Short access day 10 total inactive lever presses0.51.22.1-0.8-0.8-1.5-1.1-1.11.11.11.11.21.2
Short access day 1 total infusions1.41.83.21.81.81.51.11.1-1.2-1.2-1.2-1.2-1.2
Short access day 10 total infusions3.74.77.32.32.32.72.02.0-2.0-2.0-2.0-2.1-2.1
Short access total infusions2.22.84.52.02.02.11.51.5-1.5-1.5-1.5-1.6-1.6
Short access day 1 locomotion2.43.04.42.12.11.31.71.7-1.7-1.7-1.7-1.6-1.6
Short access day 10 total locomotion0.40.73.00.00.0-1.7-0.7-0.70.70.70.70.90.9
Short access total locomotion0.30.41.31.11.1-0.50.40.4-0.4-0.4-0.3-0.2-0.2
One hour access (0.3 mA shock)0.10.10.30.60.60.20.10.1-0.1-0.1-0.1-0.1-0.1
Compulsive drug intake0.10.10.20.40.40.30.40.4-0.4-0.4-0.4-0.2-0.2
One hour access (shock baseline)0.50.81.31.11.11.10.70.7-0.7-0.7-0.8-1.0-1.0
Social response proportion1.11.32.40.90.91.51.11.1-1.1-1.1-1.1-1.1-1.1
Social responses2.12.73.41.21.21.71.81.8-1.8-1.8-1.8-1.6-1.6
Social time0.60.83.3-1.8-1.8-0.2-0.2-0.20.30.30.40.60.6
Soleus weight0.51.42.51.61.60.21.11.1-1.1-1.1-1.1-1.1-1.1
Bone: stiffness1.11.82.61.11.10.41.61.6-1.5-1.5-1.5-1.4-1.4
Tibialis anterior weight3.110.614.63.83.81.93.23.2-3.3-3.3-3.3-3.1-3.1
Time to tail flick, vehicle, before self-admin0.20.31.00.80.8-1.00.10.1-0.1-0.1-0.20.20.2
Time to tail flick, vehicle, after self-admin0.20.30.9-1.0-1.0-0.3-0.5-0.50.50.50.50.30.3
Time to tail flick, test, before self-admin1.92.03.1-1.3-1.3-1.7-1.3-1.31.41.41.41.51.5
Time to tail flick, test, after self-admin0.20.20.40.50.5-0.7-0.4-0.40.30.30.30.20.2
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.9-0.90.2-0.2-0.20.20.20.2-0.1-0.1
Delta time to tail flick, test, before/after SA1.01.12.71.61.60.40.80.8-0.8-0.8-0.9-0.9-0.9
Tibia length1.54.15.11.51.52.02.32.3-2.2-2.2-2.1-2.1-2.1
Ambulatory time before self-admin0.10.10.4-0.5-0.5-0.60.20.2-0.1-0.1-0.00.20.2
Ambulatory time after self-admin0.80.91.3-0.9-0.9-1.1-0.8-0.80.90.90.91.11.1
Bone: tissue strength0.20.20.3-0.4-0.4-0.2-0.4-0.40.40.40.40.50.5
Total heroin consumption0.10.20.80.10.10.90.30.3-0.3-0.3-0.3-0.3-0.3
Bone: trabecular number0.20.31.2-0.2-0.2-1.1-0.4-0.40.40.40.40.60.6
Bone: trabecular spacing0.00.10.20.00.00.50.20.2-0.2-0.2-0.2-0.3-0.3
Bone: trabecular thickness0.40.50.90.90.9-0.40.70.7-0.7-0.7-0.7-0.7-0.7
Bone: trabecular tissue density0.50.75.60.50.52.40.20.2-0.3-0.3-0.3-0.5-0.5
Water consumed over 24 hours0.81.12.3-0.9-0.9-1.5-0.9-0.91.01.01.01.11.1
Number of responses in last shaping day2.52.84.41.81.82.11.41.4-1.5-1.5-1.5-1.7-1.7