Hub : Genes

Zfp296

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Zfp296	0.45	0.11	0.0e+00	0.5	0.51	0.5	0.5	2.1e-63	4.4e-65	5.1e-63	4.1e-63
2	NAcc	gene expression	Zfp296	0.24	0.1	0.0e+00	0.29	0.29	0.29	0.28	1.5e-44	9.9e-45	1.8e-44	4.2e-43
3	RMTg	gene expression	Zfp296	0.26	0.14	4.2e-07	0.13	0.16	0.16	0.17	2.8e-04	6.1e-05	5.2e-05	2.3e-05
4	BLA	gene expression	Zfp296	0.45	0.15	0.0e+00	0.35	0.37	0.35	0.36	1.5e-19	9.7e-21	3.0e-19	1.1e-19
5	IL	gene expression	Zfp296	0.61	0.21	1.1e-10	0.38	0.36	0.34	0.37	4.7e-10	1.6e-09	6.1e-09	7.9e-10
6	OFC	gene expression	Zfp296	0.37	0.14	1.9e-09	0.35	0.33	0.32	0.34	3.4e-09	1.1e-08	1.8e-08	8.8e-09
7	pVTA	gene expression	Zfp296	0.28	0.15	0.0e+00	0.19	0.2	0.18	0.19	3.9e-15	1.2e-15	2.7e-14	2.4e-15
8	LHb	gene expression	Zfp296	0.45	0.15	7.8e-12	0.48	0.45	0.48	0.48	5.5e-13	4.4e-12	6.8e-13	4.1e-13
9	Brain	gene expression	Zfp296	0.52	0.16	0.0e+00	0.51	0.51	0.51	0.51	1.2e-54	3.0e-55	5.1e-55	5.6e-55
10	IC	gene expression	Zfp296	0.33	0.16	3.6e-12	0.25	0.21	0.23	0.23	9.8e-11	3.8e-09	6.9e-10	3.4e-10
11	Adipose	gene expression	Zfp296	0.39	0.17	0.0e+00	0.32	0.31	0.32	0.32	1.3e-36	1.0e-34	8.6e-37	7.2e-36
12	Liver	gene expression	Zfp296	0.09	0.05	1.1e-13	0.11	0.11	0.11	0.11	5.9e-12	5.9e-12	4.7e-12	6.5e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bone: apparent density	0.0	0.1	0.3	-0.1	-0.0	-0.1	-0.1	-0.2	-0.2	-0.2	-0.2	-0.4	0.5	0.3	0.0
Area under the delay curve	1.4	2.1	3.3	1.4	1.5	1.4	1.3	-1.3	-1.3	1.4	1.6	1.4	-1.7	-1.8	-1.1
BMI with tail	0.6	2.0	2.7	-1.4	-1.2	-1.6	-1.5	1.3	1.3	-1.6	-1.5	-1.6	1.7	1.5	1.0
BMI without tail	0.3	1.7	2.1	-1.4	-1.3	-1.4	-1.4	1.3	1.3	-1.3	-1.4	-1.2	1.0	1.1	1.2
Body weight	1.1	5.0	6.7	-2.2	-2.0	-2.3	-2.3	2.1	2.1	-2.3	-2.2	-2.5	2.6	2.3	1.8
Weight adjusted by age	0.0	0.0	0.0	0.0	-0.1	-0.0	-0.0	0.1	0.1	-0.0	-0.0	0.1	0.2	0.0	-0.0
Bone surface	0.3	0.6	1.2	-0.8	-0.6	-0.8	-0.8	0.6	0.6	-0.8	-0.8	-1.0	1.1	1.0	0.6
Bone volume	0.2	0.5	1.0	-0.7	-0.5	-0.6	-0.6	0.4	0.4	-0.7	-0.7	-1.0	1.0	0.9	0.4
Breakpoint value in progressive ratio session	1.5	2.7	3.2	1.7	1.8	1.7	1.6	-1.6	-1.6	1.6	1.6	1.5	-1.5	-1.6	-1.6
Number of licking bursts	0.9	2.9	4.4	-1.7	-1.6	-1.7	-1.8	2.1	2.1	-1.7	-1.4	-1.6	1.5	1.5	1.6
Context. condit. distance diff. score	0.1	0.1	0.2	-0.3	-0.2	-0.3	-0.4	0.3	0.3	-0.4	-0.4	-0.5	0.4	0.4	-0.0
Locomotion velocity, session 1	0.1	0.1	0.2	0.3	0.5	0.3	0.2	-0.3	-0.3	0.2	0.3	0.1	0.4	-0.1	-0.4
Locomotion distance, session 1	0.1	0.2	0.6	-0.2	-0.2	-0.4	-0.3	0.1	0.1	-0.3	-0.3	-0.6	0.7	0.6	0.6
Locomotion velocity, session 2	0.9	1.1	1.6	-1.1	-1.2	-1.0	-1.1	1.3	1.3	-1.0	-1.0	-0.8	1.1	1.0	0.8
Locomotion distance, session 2	0.4	0.5	0.9	-0.7	-0.8	-0.7	-0.7	0.5	0.5	-0.7	-0.8	-0.7	0.9	0.9	0.7
Locomotion velocity, session 3	0.2	0.2	0.4	-0.5	-0.6	-0.4	-0.4	0.5	0.5	-0.4	-0.5	-0.3	0.3	0.4	0.2
Locomotion distance, session 3	0.7	0.8	1.4	0.9	0.6	1.0	1.0	-0.9	-0.9	0.9	0.9	1.2	-0.9	-0.8	-0.8
Stereotopy head waving bouts, day 3	0.7	0.8	1.5	-0.9	-1.1	-0.9	-0.9	1.1	1.1	-0.8	-0.7	-0.3	0.4	0.5	1.2
Stereotopy head waving duration, day 3	0.9	1.1	1.7	-1.1	-1.1	-1.2	-1.1	1.2	1.2	-1.1	-1.0	-0.8	0.6	0.8	1.3
Locomotion velocity, session 7	0.1	0.1	0.2	0.4	0.3	0.4	0.3	-0.4	-0.4	0.2	0.1	0.1	-0.4	-0.1	0.0
Locomotion distance, session 7	0.1	0.1	0.4	-0.1	-0.1	-0.1	-0.3	0.2	0.2	-0.3	-0.4	-0.4	0.6	0.4	-0.3
Stereotopy head waving bouts, day 7	0.8	1.0	1.2	-1.0	-1.0	-1.0	-1.0	1.0	1.0	-1.0	-1.0	-0.9	0.7	1.0	1.1
Stereotopy head waving duration, day 7	0.6	0.8	0.9	-0.9	-0.9	-0.9	-0.9	1.0	1.0	-0.9	-0.9	-0.8	0.6	0.8	0.8
Locomotion velocity, session 8	0.1	0.1	0.3	0.1	-0.1	0.2	0.1	-0.0	-0.0	0.2	0.2	0.4	-0.6	-0.3	-0.3
Locomotion distance, session 8	0.1	0.1	0.4	-0.2	-0.1	-0.1	-0.2	-0.0	-0.0	-0.2	-0.4	-0.4	0.6	0.4	-0.1
Degree of sensitization distance	0.6	0.7	1.2	-0.7	-0.5	-0.9	-0.9	0.8	0.8	-0.9	-0.9	-1.1	1.0	0.7	0.4
Degree of sensitization stereotypy	0.9	1.0	1.2	-1.0	-1.0	-1.0	-1.0	1.0	1.0	-1.0	-1.0	-1.0	0.8	1.1	1.0
Conditioned locomotion	0.1	0.1	0.4	0.3	-0.1	0.2	0.3	-0.2	-0.2	0.3	0.3	0.6	-0.4	-0.1	0.2
Cocaine response after cond. corrected	0.5	0.8	1.2	-0.7	-0.8	-0.8	-0.8	0.8	0.8	-0.9	-0.9	-0.8	1.1	1.1	0.7
Cocaine response after cond. not corrected	1.3	1.9	2.8	-1.2	-1.3	-1.4	-1.3	1.3	1.3	-1.4	-1.4	-1.3	1.7	1.7	1.0
Cocaine response before conditioning	1.4	1.7	2.2	-1.3	-1.5	-1.4	-1.3	1.3	1.3	-1.3	-1.4	-1.1	1.3	1.3	0.8
Saline control response	2.0	2.7	3.9	-1.8	-1.7	-1.6	-1.6	1.7	1.7	-1.6	-1.6	-1.6	1.3	1.5	2.0
Bone: connectivity density	0.0	0.0	0.1	0.0	0.1	0.0	0.1	-0.4	-0.4	-0.0	-0.0	-0.2	0.1	0.1	0.2
Bone: cortical apparent density	0.1	0.1	0.3	0.2	0.3	0.4	0.3	-0.4	-0.4	0.3	0.2	0.1	-0.5	-0.3	-0.3
Bone: cortical area	1.4	2.3	2.8	-1.7	-1.5	-1.5	-1.6	1.6	1.6	-1.5	-1.5	-1.6	1.4	1.5	1.3
Bone: cortical porosity	0.4	0.4	1.6	0.6	0.2	0.7	0.7	-0.3	-0.3	0.7	0.7	1.2	-0.3	-0.5	-0.5
Bone: cortical porosity	0.1	0.1	0.7	0.2	-0.2	0.3	0.3	0.1	0.1	0.3	0.3	0.8	-0.1	-0.2	0.1
Bone: cortical thickness	0.6	0.9	1.2	-1.1	-1.1	-1.0	-1.0	1.0	1.0	-1.0	-1.0	-0.9	0.7	0.9	1.1
Bone: cortical thickness	1.4	1.7	2.6	-1.4	-1.4	-1.4	-1.3	1.3	1.3	-1.3	-1.3	-1.2	1.6	1.4	0.8
Bone: cortical tissue density	0.1	0.2	0.4	0.4	0.4	0.5	0.4	-0.6	-0.6	0.4	0.3	0.2	-0.6	-0.4	-0.4
Condit. Reinf. active minus inactive responses	0.4	0.4	0.7	-0.6	-0.6	-0.7	-0.7	0.5	0.5	-0.8	-0.7	-0.8	0.8	0.8	0.2
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.8	-0.6	-0.5	-0.7	-0.6	0.3	0.3	-0.7	-0.8	-0.9	0.8	0.8	0.1
Condit. Reinf. active responses	0.3	0.4	0.7	-0.6	-0.5	-0.7	-0.6	0.4	0.4	-0.7	-0.7	-0.7	0.8	0.7	0.1
Condit. Reinf. inactive responses	0.0	0.0	0.1	-0.0	-0.0	-0.0	0.1	-0.3	-0.3	0.0	-0.1	-0.0	0.1	0.1	-0.2
Incentive salience index mean	0.2	0.3	0.4	-0.5	-0.5	-0.5	-0.5	0.4	0.4	-0.5	-0.5	-0.5	0.6	0.7	0.4
Condit. Reinf. lever presses	0.0	0.1	0.5	-0.0	-0.2	0.1	-0.0	0.0	0.0	-0.1	-0.1	-0.1	0.3	0.3	0.7
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	-0.3	-0.3	-0.5	-0.4	0.2	0.2	-0.4	-0.4	-0.4	0.5	0.5	-0.0
Condit. Reinf. active-inactive response ratio	0.4	0.7	1.2	-0.7	-0.8	-0.9	-0.7	0.6	0.6	-0.9	-0.9	-0.8	1.0	1.1	0.4
Condit. Reinf. active responses	0.1	0.1	0.2	0.3	0.2	0.2	0.3	-0.4	-0.4	0.3	0.3	0.4	-0.4	-0.4	-0.5
Condit. Reinf. inactive responses	0.7	1.1	1.7	0.9	0.9	1.0	1.0	-1.0	-1.0	1.0	1.0	1.1	-1.3	-1.3	-1.0
Condit. Reinf. lever presses	0.2	0.2	0.5	-0.4	-0.3	-0.6	-0.6	0.4	0.4	-0.6	-0.5	-0.7	0.6	0.4	0.2
Condit. Reinf. lever reinforcers received	0.1	0.1	0.2	0.4	0.3	0.3	0.4	-0.4	-0.4	0.4	0.3	0.5	-0.5	-0.4	-0.4
Conditioned reinforcement - actives	0.6	2.2	2.8	-1.6	-1.7	-1.6	-1.5	1.4	1.4	-1.5	-1.6	-1.3	1.2	1.3	1.5
Conditioned reinforcement - inactives	0.2	0.5	0.8	-0.7	-0.9	-0.8	-0.7	0.8	0.8	-0.7	-0.8	-0.6	0.6	0.6	0.9
Conditioned locomotion	2.0	3.0	3.5	-1.7	-1.8	-1.9	-1.8	1.7	1.7	-1.8	-1.8	-1.6	1.8	1.8	1.5
Patch foraging indifference point 0 sec	0.3	0.7	1.1	-0.8	-0.9	-0.9	-0.9	0.8	0.8	-0.8	-0.7	-0.8	1.0	0.9	0.8
Patch foraging indifference point AUC	1.6	3.8	5.3	-2.0	-2.1	-2.0	-2.0	2.2	2.2	-1.9	-2.0	-1.7	1.1	1.6	2.3
Delay disc. indifference point, 0s delay	1.3	1.5	2.1	1.2	1.1	1.2	1.3	-1.2	-1.2	1.3	1.3	1.4	-1.3	-1.3	-0.8
Delay disc. indifference point, 16s delay	1.0	1.4	2.2	1.0	1.2	1.1	1.0	-1.2	-1.2	1.1	1.3	1.0	-1.4	-1.5	-1.2
Delay disc. indifference point, 2s delay	3.7	4.2	5.5	2.2	2.3	2.1	2.0	-1.8	-1.8	2.1	2.3	1.9	-2.1	-2.3	-1.5
Delay disc. indifference point, 24s delay	0.1	0.2	0.6	-0.3	-0.1	-0.4	-0.5	0.2	0.2	-0.5	-0.4	-0.7	0.8	0.4	-0.5
Delay disc. indifference point, 4s delay	0.0	0.0	0.1	0.1	0.0	-0.1	0.0	0.1	0.1	0.1	0.1	0.3	-0.2	-0.3	0.2
Delay disc. indifference point, 8s delay	1.3	2.1	3.4	1.3	1.5	1.4	1.4	-1.3	-1.3	1.4	1.6	1.4	-1.8	-1.8	-1.2
Indifference point function ln k	0.4	1.2	2.0	1.0	1.1	1.1	1.1	-1.3	-1.3	1.0	1.0	0.8	-0.7	-0.9	-1.4
Indifference point function log k	0.4	1.2	2.0	1.0	1.1	1.1	1.1	-1.3	-1.3	1.0	1.0	0.8	-0.7	-0.9	-1.4
Patch foraging total patch changes 0 sec	0.4	1.3	2.0	-1.1	-1.1	-1.2	-1.1	1.0	1.0	-1.1	-1.0	-1.2	1.4	1.2	1.0
Patch foraging total patch changes 12 sec	1.1	1.5	2.2	-1.1	-1.3	-1.3	-1.2	1.4	1.4	-1.2	-1.1	-0.9	0.8	1.1	1.5
Patch foraging total patch changes 18 sec	1.3	3.1	3.8	-1.7	-1.6	-1.9	-1.8	1.7	1.7	-1.8	-1.7	-2.0	1.8	1.8	1.5
Patch foraging total patch changes 24 sec	0.2	0.6	0.9	-0.7	-0.7	-0.9	-0.8	0.7	0.7	-0.8	-0.7	-0.7	0.5	0.7	0.9
Patch foraging total patch changes 6 sec	2.1	3.6	4.7	-2.0	-2.2	-2.0	-1.9	1.9	1.9	-1.8	-1.9	-1.6	1.6	1.7	2.2
Patch foraging time to switch 0 sec	1.5	5.6	6.4	2.5	2.5	2.4	2.4	-2.2	-2.2	2.4	2.4	2.3	-2.1	-2.4	-2.4
Patch foraging water rate 0 sec	1.7	6.3	7.4	-2.5	-2.7	-2.6	-2.5	2.4	2.4	-2.6	-2.6	-2.4	2.1	2.5	2.7
Patch foraging water rate 12 sec	0.1	0.5	0.8	-0.7	-0.6	-0.7	-0.6	0.4	0.4	-0.7	-0.7	-0.8	0.8	0.7	0.9
Patch foraging water rate 18 sec	0.1	0.3	0.6	-0.6	-0.5	-0.5	-0.5	0.4	0.4	-0.5	-0.6	-0.7	0.7	0.5	0.6
Patch foraging water rate 24 sec	0.6	0.9	1.1	-1.0	-1.0	-1.0	-1.0	0.9	0.9	-1.0	-1.0	-1.0	0.7	0.9	0.9
Patch foraging water rate 6 sec	0.8	1.2	2.2	-1.1	-0.9	-1.1	-1.1	0.9	0.9	-1.2	-1.2	-1.5	1.0	1.1	1.0
Seeking ratio, delayed vs. immediate footshock	1.6	2.3	2.7	1.5	1.3	1.5	1.6	-1.6	-1.6	1.5	1.4	1.6	-1.7	-1.5	-1.4
Distance traveled before self-admin	0.1	0.1	0.2	-0.4	-0.3	-0.3	-0.3	0.3	0.3	-0.3	-0.2	-0.4	0.3	0.4	0.3
Distance traveled after self-admin	0.1	0.2	0.7	0.3	0.3	0.4	0.5	-0.4	-0.4	0.5	0.4	0.5	-0.8	-0.5	-0.4
Extensor digitorum longus weight	1.8	7.0	8.5	-2.8	-2.4	-2.6	-2.7	2.8	2.8	-2.6	-2.5	-2.9	2.9	2.7	2.2
Bone: elastic displacement	0.9	1.2	1.4	1.2	1.1	1.2	1.2	-1.1	-1.1	1.1	1.0	1.2	-0.6	-1.0	-1.1
Bone: elastic work	0.0	0.0	0.2	-0.1	-0.3	-0.1	-0.1	0.1	0.1	-0.1	-0.2	0.1	0.5	0.2	0.1
Bone: endosteal estimation	0.0	0.0	0.2	0.2	0.3	0.2	0.2	-0.2	-0.2	0.1	0.1	0.0	0.1	-0.0	-0.5
Bone: endosteal perimeter	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	-0.0	0.1	-0.2	0.1	0.0	-0.2
Epididymis fat weight	0.2	1.0	1.3	0.9	1.0	1.1	1.0	-0.9	-0.9	1.0	1.0	1.0	-1.0	-1.1	-1.2
Delta time in closed arm before/after self-admin	0.1	0.1	0.1	0.2	0.3	0.2	0.2	-0.4	-0.4	0.2	0.2	0.0	-0.1	-0.2	-0.2
Delta time in open arm before/after self-admin	0.0	0.0	0.1	0.1	0.0	0.2	0.2	-0.1	-0.1	0.2	0.1	0.3	-0.3	-0.2	-0.4
Diff in mean of infusions in LGA sessions	0.9	1.6	2.0	1.4	1.4	1.3	1.3	-1.3	-1.3	1.3	1.2	1.2	-1.2	-1.3	-1.1
Delay discount exponential model param	1.1	1.5	2.4	-1.1	-1.3	-1.1	-1.1	1.1	1.1	-1.2	-1.4	-1.1	1.4	1.5	1.0
Extinction: sum of active levers before priming	0.1	0.1	0.3	0.3	0.2	0.3	0.3	-0.2	-0.2	0.3	0.1	0.6	-0.2	-0.3	0.0
Active lever presses in extinction session 6	0.2	0.2	0.8	0.0	-0.1	-0.2	-0.3	0.2	0.2	-0.3	-0.3	-0.4	0.9	0.5	0.4
Bone: final force	0.4	0.6	0.8	-0.8	-0.8	-0.8	-0.8	0.8	0.8	-0.8	-0.7	-0.7	0.9	0.8	0.5
Bone: final moment	0.5	0.9	1.0	-0.9	-0.9	-1.0	-1.0	0.9	0.9	-1.0	-0.9	-0.8	0.9	1.0	0.8
Food consumed during 24 hour testing period	3.1	6.3	7.6	2.6	2.5	2.5	2.5	-2.8	-2.8	2.5	2.4	2.4	-2.3	-2.4	-2.6
Glucose	0.3	0.5	0.8	0.8	0.7	0.6	0.6	-0.6	-0.6	0.6	0.7	0.9	-0.8	-0.8	-0.3
Heart weight	2.0	3.2	3.6	-1.8	-1.8	-1.8	-1.8	1.9	1.9	-1.8	-1.8	-1.7	1.7	1.7	1.7
Delay discount hyperbolic model param	1.1	1.4	2.3	-1.1	-1.3	-1.1	-1.1	1.0	1.0	-1.2	-1.3	-1.1	1.4	1.5	0.9
Intermittent access intake day 1-15 change	0.0	0.2	0.4	-0.4	-0.3	-0.4	-0.5	0.4	0.4	-0.4	-0.4	-0.5	0.6	0.4	0.3
Intermittent access intake escalation	0.0	0.3	0.4	-0.5	-0.4	-0.6	-0.6	0.5	0.5	-0.5	-0.5	-0.6	0.6	0.5	0.4
Intermittent access intake escalation 2	0.0	0.0	0.1	-0.0	-0.1	-0.1	-0.1	0.1	0.1	-0.1	-0.2	-0.0	0.2	0.1	0.2
Intermitt. access day 1 inactive lever presses	0.0	0.0	0.3	-0.0	-0.0	-0.1	-0.1	0.1	0.1	-0.1	-0.1	-0.1	0.4	0.1	0.6
Intermitt. access day 15 inactive lever presses	0.0	0.0	0.1	-0.1	0.1	-0.0	-0.1	0.0	0.0	-0.1	-0.0	-0.4	0.2	-0.0	0.0
Intermitt. access escalation Index	0.1	0.3	0.4	0.6	0.6	0.7	0.6	-0.6	-0.6	0.6	0.6	0.5	-0.4	-0.5	0.2
Intermittent access day 1 total infusions	0.7	2.2	2.8	-1.6	-1.7	-1.6	-1.5	1.5	1.5	-1.5	-1.6	-1.3	0.9	1.1	1.6
Intermittent access day 15 total infusions	0.4	1.1	1.4	-1.1	-1.0	-1.2	-1.1	1.1	1.1	-1.1	-1.1	-1.1	0.8	0.8	1.0
Intermittent access terminal intake (last 3 days)	0.8	1.5	1.8	-1.3	-1.2	-1.3	-1.3	1.2	1.2	-1.3	-1.3	-1.2	1.0	0.9	1.2
Intermittent access total infusions	2.4	2.8	3.4	-1.8	-1.7	-1.8	-1.8	1.7	1.7	-1.8	-1.8	-1.6	1.4	1.4	1.6
Intermittent access day 1 locomotion	0.2	0.4	0.9	-0.6	-0.8	-0.7	-0.6	0.6	0.6	-0.6	-0.7	-0.4	0.3	0.5	0.9
Intermittent access day 15 total locomotion	0.1	0.2	0.3	-0.5	-0.6	-0.6	-0.5	0.5	0.5	-0.5	-0.5	-0.3	0.2	0.3	0.6
Intermittent access total locomotion	1.6	1.9	2.5	-1.4	-1.5	-1.6	-1.5	1.4	1.4	-1.5	-1.5	-1.2	0.9	1.1	1.4
Intermittent access standard deviation	0.0	0.2	0.3	0.5	0.5	0.4	0.4	-0.4	-0.4	0.4	0.4	0.5	-0.1	-0.4	-0.4
Left kidney weight	3.2	25.5	27.9	-5.3	-5.3	-5.2	-5.1	4.9	4.9	-5.2	-5.3	-5.0	5.2	5.2	3.9
Right kidney weight	3.3	23.2	24.7	-4.9	-4.9	-4.9	-4.9	4.7	4.7	-4.9	-4.9	-4.8	4.9	5.0	4.0
Cocaine induced anxiety	0.1	0.3	0.6	0.5	0.6	0.5	0.5	-0.5	-0.5	0.6	0.6	0.5	-0.7	-0.8	-0.2
Post-drug Anxiety	0.1	0.1	0.1	0.2	0.3	0.3	0.2	-0.1	-0.1	0.3	0.3	0.2	-0.3	-0.4	0.0
Baseline Anxiety	0.0	0.0	0.1	0.0	-0.1	-0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.1	0.1	-0.2
Tail length	0.2	1.1	1.4	-1.2	-1.1	-1.1	-1.1	1.1	1.1	-1.0	-1.0	-1.0	0.7	0.9	0.9
Length with tail	0.3	1.4	2.0	-1.3	-1.2	-1.2	-1.2	1.1	1.1	-1.2	-1.1	-1.3	1.4	1.2	0.9
Length without tail	0.3	1.7	4.7	-1.1	-0.9	-1.2	-1.3	0.9	0.9	-1.3	-1.1	-1.7	2.2	1.6	0.6
Times rat made contact with spout	0.1	0.1	0.3	0.0	0.0	-0.1	-0.0	-0.2	-0.2	-0.1	-0.2	-0.2	0.5	0.4	-0.5
Lifetime Intake	2.2	2.7	3.2	-1.8	-1.7	-1.8	-1.7	1.7	1.7	-1.7	-1.7	-1.5	1.3	1.4	1.6
Liver weight, left	1.7	3.0	3.9	-1.9	-2.0	-1.8	-1.7	1.9	1.9	-1.7	-1.6	-1.3	1.5	1.5	1.8
Liver weight, right	1.3	2.3	3.4	-1.6	-1.5	-1.6	-1.5	1.3	1.3	-1.6	-1.6	-1.7	1.8	1.6	1.0
Locomotor activity	1.9	3.0	4.3	-2.0	-2.0	-1.6	-1.7	2.0	2.0	-1.6	-1.6	-1.4	1.2	1.3	2.1
Locomotor testing distance	0.8	2.0	4.6	-1.5	-1.6	-1.3	-1.3	1.6	1.6	-1.2	-1.3	-1.1	0.8	1.0	2.1
Locomotor testing rearing	2.3	8.3	10.2	-2.9	-2.9	-2.9	-2.9	3.0	3.0	-2.9	-2.9	-2.8	2.5	2.7	3.2
Locomotion in novel chamber	0.1	0.2	0.4	0.4	0.4	0.5	0.4	-0.3	-0.3	0.4	0.4	0.4	-0.6	-0.5	0.1
Locomotion in novel chamber post-restriction	0.4	1.2	1.5	1.1	1.1	1.1	1.2	-1.2	-1.2	1.2	1.2	1.2	-1.1	-1.1	-0.3
Fecal boli incidents, locomotor time 1	0.0	0.0	0.1	-0.1	-0.2	-0.1	-0.1	0.2	0.2	-0.1	-0.1	-0.1	0.3	0.1	0.3
Change in fecal boli incidents, locomotor task	0.8	0.8	1.1	0.9	0.9	0.8	0.9	-0.9	-0.9	0.9	1.0	0.8	-1.0	-1.0	-0.9
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.2	-0.1	0.0	-0.1	-0.1	-0.1	-0.1	-0.2	-0.3	-0.2	0.0	0.2	-0.4
Bouts of movement, locomotor time 1	1.7	2.3	2.7	1.5	1.6	1.6	1.5	-1.7	-1.7	1.5	1.5	1.3	-1.3	-1.5	-1.3
Total resting periods, locomotor time 1	2.6	3.0	3.5	1.7	1.9	1.8	1.8	-1.9	-1.9	1.7	1.8	1.5	-1.6	-1.8	-1.5
Rest time, locomotor task time 1	0.1	0.2	0.4	0.4	0.4	0.4	0.4	-0.5	-0.5	0.4	0.4	0.3	-0.4	-0.5	-0.6
Distance moved, locomotor task time 1	0.2	0.5	0.7	-0.5	-0.8	-0.7	-0.6	0.8	0.8	-0.6	-0.6	-0.3	0.7	0.8	0.8
Vertical activity count, locomotor time 1	0.0	0.0	0.2	0.3	-0.0	0.1	0.2	-0.0	-0.0	0.2	0.2	0.5	0.1	-0.0	0.1
Time >=10cm from walls, locomotor time 2	0.0	0.1	0.3	0.5	0.3	0.1	0.3	-0.2	-0.2	0.3	0.3	0.6	-0.4	-0.3	0.2
Bouts of movement, locomotor time 2	1.8	6.0	8.1	2.7	2.8	2.6	2.5	-2.7	-2.7	2.4	2.4	2.0	-1.8	-2.2	-2.1
Total resting periods, locomotor time 2	1.3	5.2	7.0	2.5	2.6	2.5	2.4	-2.5	-2.5	2.3	2.3	1.9	-1.6	-2.0	-1.9
Rest time, locomotor task time 2	0.0	0.0	0.1	-0.0	-0.1	0.2	0.2	-0.3	-0.3	0.2	0.0	0.0	-0.1	-0.1	-0.2
Distance moved, locomotor task time 2	0.6	0.8	1.3	-0.7	-0.9	-1.0	-0.9	1.0	1.0	-0.9	-0.8	-0.6	1.0	0.9	1.1
Vertical activity count, locomotor time 2	0.1	0.1	0.4	0.6	0.5	0.3	0.4	-0.2	-0.2	0.4	0.5	0.5	0.1	-0.3	0.1
Light reinforcement 1	0.0	0.2	0.5	-0.4	-0.4	-0.5	-0.5	0.3	0.3	-0.5	-0.7	-0.5	0.6	0.5	0.1
Light reinforcement 2	0.1	0.1	0.3	-0.3	-0.2	-0.2	-0.3	0.3	0.3	-0.3	-0.5	-0.4	0.6	0.3	0.4
Bone: marrow area	0.0	0.0	0.2	0.2	0.3	0.1	0.1	-0.1	-0.1	0.1	0.1	0.0	0.1	0.1	-0.4
Bone: maximum diameter	1.9	3.9	4.4	-2.1	-1.8	-1.9	-2.0	2.1	2.1	-2.0	-1.9	-2.1	1.9	2.0	1.6
Bone: maximum force	0.1	0.3	0.4	-0.6	-0.6	-0.6	-0.6	0.5	0.5	-0.6	-0.5	-0.5	0.5	0.5	0.4
Bone: maximum moment	0.2	0.4	0.5	-0.7	-0.7	-0.7	-0.7	0.7	0.7	-0.7	-0.6	-0.6	0.5	0.6	0.6
Mean time between licks in bursts	0.0	0.1	0.2	0.3	0.2	0.1	0.3	-0.3	-0.3	0.3	0.3	0.5	-0.4	-0.3	-0.2
Mean num. licks in bursts	1.0	2.7	4.7	1.7	1.6	1.6	1.8	-2.2	-2.2	1.6	1.3	1.5	-1.1	-1.2	-1.9
Cd content in liver	0.1	0.1	0.3	0.2	0.3	0.0	0.0	-0.3	-0.3	-0.1	-0.1	-0.3	0.4	0.3	-0.5
Co content in liver	1.3	1.6	2.2	1.4	1.2	1.3	1.3	-1.2	-1.2	1.2	1.3	1.3	-1.1	-1.0	-1.5
Cu content in liver	0.2	0.3	0.5	-0.6	-0.5	-0.5	-0.6	0.7	0.7	-0.5	-0.3	-0.6	0.3	0.5	0.3
Fe content in liver	4.1	5.0	6.5	-2.5	-2.2	-2.2	-2.4	2.5	2.5	-2.2	-2.0	-2.4	2.2	2.0	1.6
K content in liver	0.1	0.1	0.2	-0.3	-0.3	-0.1	-0.2	0.5	0.5	-0.1	0.1	-0.0	0.0	0.1	0.2
Mg content in liver	0.3	0.3	0.7	-0.6	-0.8	-0.6	-0.6	0.8	0.8	-0.5	-0.4	-0.2	0.1	0.5	0.6
Mn content in liver	0.9	1.0	2.0	-0.9	-1.4	-1.0	-0.9	1.0	1.0	-1.0	-1.0	-0.4	0.8	1.1	1.1
Na content in liver	0.1	0.1	0.4	-0.4	-0.4	-0.3	-0.4	0.6	0.6	-0.3	-0.2	-0.1	0.4	0.2	-0.2
Rb content in liver	0.2	0.2	0.4	-0.4	-0.3	-0.4	-0.4	0.3	0.3	-0.5	-0.4	-0.6	0.4	0.6	-0.5
Se content in liver	3.1	3.6	5.2	-2.0	-2.2	-1.9	-1.9	2.2	2.2	-1.8	-1.8	-1.5	1.4	1.6	2.3
Sr content in liver	0.0	0.0	0.0	-0.1	-0.2	0.0	-0.0	0.2	0.2	0.0	-0.1	0.2	-0.1	-0.1	0.2
Zn content in liver	0.7	0.8	1.2	-0.8	-0.8	-0.9	-0.9	1.0	1.0	-0.9	-0.8	-0.9	1.0	1.1	0.4
Bone: minimum diameter	0.2	0.4	0.4	-0.6	-0.6	-0.7	-0.6	0.6	0.6	-0.6	-0.6	-0.7	0.6	0.6	0.4
Time in familiar zone, hab. session 1	0.2	0.2	0.7	-0.4	-0.3	-0.3	-0.4	0.5	0.5	-0.4	-0.4	-0.4	0.8	0.5	0.2
Time in novel zone, hab. session 1	0.5	0.5	0.9	-0.7	-0.7	-0.9	-0.8	0.8	0.8	-0.8	-0.8	-0.6	0.4	0.6	0.5
Total zone transitions, hab. session 1	0.3	0.4	1.5	-0.6	-0.5	-0.7	-0.6	0.4	0.4	-0.6	-0.7	-0.7	1.2	0.7	0.2
Total locomotion distance, hab. session 1	0.3	0.5	0.6	0.7	0.7	0.6	0.7	-0.7	-0.7	0.8	0.8	0.7	-0.2	-0.7	-0.8
Locomotion velocity, hab. session 1	1.1	1.5	1.8	1.3	1.3	1.2	1.3	-1.3	-1.3	1.3	1.3	1.2	-0.8	-1.2	-1.1
Time in familiar zone, hab. session 2	0.2	0.2	0.8	-0.4	-0.3	-0.5	-0.5	0.5	0.5	-0.4	-0.3	-0.6	0.4	0.3	0.9
Time in novel zone, hab. session 2	0.1	0.1	0.5	0.2	0.2	0.1	0.1	-0.2	-0.2	0.0	0.0	0.2	-0.1	-0.1	-0.7
Total zone transitions, hab. session 2	0.5	0.6	1.0	-0.6	-0.9	-0.8	-0.8	0.8	0.8	-0.7	-0.7	-0.6	1.0	0.9	0.9
Total locomotion distance, hab. session 2	0.5	0.7	1.0	1.0	0.8	0.9	0.9	-0.8	-0.8	0.9	1.0	0.9	-0.4	-0.7	-0.6
Locomotion velocity, hab. session 2	0.3	0.4	0.6	0.8	0.6	0.7	0.7	-0.7	-0.7	0.7	0.8	0.7	-0.1	-0.5	-0.4
Novel to familiar place preference ratio	0.8	1.1	1.7	-1.1	-1.0	-1.1	-1.0	0.7	0.7	-1.2	-1.3	-1.3	0.9	1.2	0.5
Novelty place preference	0.7	0.9	1.5	-1.0	-0.9	-1.0	-1.0	0.7	0.7	-1.1	-1.2	-1.2	0.8	1.1	0.5
Time in novel zone, NPP test	0.9	1.1	1.8	-1.1	-1.0	-1.2	-1.1	0.8	0.8	-1.2	-1.4	-1.2	0.9	1.2	0.6
Total zone transitions, NPP test	0.1	0.2	0.7	-0.4	-0.4	-0.3	-0.4	0.4	0.4	-0.4	-0.3	-0.5	0.8	0.5	0.3
Total locomotion distance, NPP test	0.2	0.2	1.0	-0.4	-0.2	-0.3	-0.4	0.4	0.4	-0.4	-0.3	-0.6	1.0	0.5	0.4
Locomotion velocity, NPP test	0.1	0.2	0.9	-0.4	-0.2	-0.2	-0.3	0.3	0.3	-0.3	-0.3	-0.6	1.0	0.5	0.4
Intraocular pressure	0.0	0.1	0.4	0.2	0.3	-0.1	-0.1	-0.1	-0.1	-0.1	0.0	-0.3	0.5	0.2	-0.6
Delta distance traveled before/after self-admin	1.9	2.1	2.9	1.4	1.4	1.4	1.5	-1.4	-1.4	1.5	1.3	1.5	-1.7	-1.5	-1.4
Delta ambulatory time before/after self-admin	0.3	0.6	1.0	0.6	0.6	0.7	0.7	-0.7	-0.7	0.7	0.6	0.9	-1.0	-0.9	-0.7
Parametrial fat weight	0.1	0.1	0.2	-0.3	-0.4	-0.4	-0.3	0.4	0.4	-0.3	-0.4	-0.1	0.2	0.4	0.5
Pavlov. Cond. lever latency	0.5	0.6	1.2	0.8	0.8	0.6	0.7	-0.7	-0.7	0.8	0.7	0.8	-1.1	-1.0	-0.7
Pavlov. Cond. magazine entry latency	0.1	0.2	0.7	-0.2	-0.1	-0.3	-0.3	0.2	0.2	-0.4	-0.3	-0.6	0.8	0.5	0.2
Pavlov. Cond. change in total contacts	0.5	0.5	0.8	0.9	0.8	0.7	0.8	-0.9	-0.9	0.7	0.7	0.6	-0.5	-0.4	-0.5
Pavlov. Cond. index score	0.3	0.4	1.1	-0.4	-0.5	-0.5	-0.5	0.5	0.5	-0.6	-0.5	-0.6	1.0	0.8	0.6
Pavlov. Cond. latency score	0.1	0.1	0.4	-0.1	-0.2	-0.1	-0.2	0.2	0.2	-0.2	-0.1	-0.3	0.6	0.4	0.3
Pavlov. Cond. lever contacts	0.3	0.4	0.9	-0.6	-0.6	-0.4	-0.5	0.5	0.5	-0.6	-0.5	-0.7	1.0	0.8	0.5
Pavlov. Cond. magazine entry number	0.1	0.1	0.4	-0.1	-0.1	0.1	0.1	0.0	0.0	0.2	0.1	0.4	-0.6	-0.4	-0.1
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.3	-0.3	-0.5	-0.4	-0.3	0.3	0.3	-0.4	-0.4	-0.1	-0.1	0.3	0.6
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	1.1	-0.4	-0.6	-0.5	-0.5	0.5	0.5	-0.6	-0.5	-0.6	1.0	0.8	0.8
Pavlov. Cond. response bias	1.0	1.2	2.6	-0.9	-0.9	-1.0	-1.0	0.9	0.9	-1.1	-1.0	-1.3	1.6	1.3	0.9
Pavlov. Cond. lever latency	0.0	0.1	0.5	0.0	0.0	0.2	0.2	-0.1	-0.1	0.2	0.1	0.2	-0.3	-0.2	-0.7
Pavlov. Cond. magazine entry latency	0.2	0.3	1.3	-0.1	0.1	-0.5	-0.4	0.0	0.0	-0.6	-0.6	-0.9	1.1	0.8	0.0
Pavlov. Cond. change in total contacts	0.0	0.1	0.3	0.5	0.6	0.1	0.3	-0.5	-0.5	0.2	0.2	0.1	0.2	-0.1	-0.2
Pavlov. Cond. index score	0.0	0.1	0.3	0.2	0.3	-0.2	-0.1	-0.2	-0.2	-0.2	-0.2	-0.4	0.5	0.3	0.2
Pavlov. Cond. latency score	0.0	0.1	0.2	0.3	0.4	-0.1	0.1	-0.3	-0.3	-0.1	-0.0	-0.2	0.3	0.1	0.1
Pavlov. Cond. lever contacts	0.1	0.2	0.6	-0.2	-0.2	-0.4	-0.4	0.3	0.3	-0.4	-0.3	-0.5	0.5	0.4	0.8
Pavlov. Cond. magazine entry number	0.2	0.2	0.9	-0.7	-0.9	-0.2	-0.3	0.7	0.7	-0.2	-0.3	0.2	-0.4	0.1	0.4
Pavlov. Cond. intertrial magazine entries	0.0	0.1	0.2	-0.2	-0.3	0.1	0.1	0.1	0.1	0.2	0.1	0.3	-0.3	-0.2	-0.5
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.5	-0.0	0.1	-0.4	-0.3	-0.0	-0.0	-0.4	-0.3	-0.5	0.7	0.5	0.3
Pavlov. Cond. response bias	0.0	0.1	0.3	0.1	0.2	-0.2	-0.1	-0.1	-0.1	-0.2	-0.1	-0.3	0.5	0.3	0.3
Time in closed arm before self-admin	0.6	1.1	1.3	-1.1	-1.0	-1.1	-1.1	1.0	1.0	-1.1	-1.0	-1.2	1.0	1.0	1.0
Time in closed arm after self-admin	0.6	0.7	1.1	0.8	1.1	0.8	0.7	-0.9	-0.9	0.8	0.9	0.5	-1.0	-1.0	-0.3
Time in open arm before self-admin	0.9	1.0	1.5	1.1	1.0	1.0	1.0	-0.9	-0.9	1.0	1.0	1.2	-1.0	-1.0	-1.0
Time in open arm after self-admin	0.2	0.2	0.7	0.5	0.1	0.5	0.5	-0.3	-0.3	0.5	0.3	0.9	-0.4	-0.3	-0.7
Bone: periosteal estimation	0.2	0.6	0.7	-0.8	-0.6	-0.7	-0.8	0.8	0.8	-0.8	-0.8	-0.8	0.8	0.8	0.5
Bone: periosteal perimeter	0.2	0.4	0.6	-0.7	-0.5	-0.6	-0.7	0.7	0.7	-0.6	-0.6	-0.8	0.5	0.6	0.4
Bone: post-yield work	0.6	1.0	1.5	0.9	1.0	0.8	0.9	-1.1	-1.1	0.9	0.9	0.7	-1.2	-1.1	-1.0
Progressive ratio test 1 active lever presses	1.7	3.0	4.5	-1.9	-2.1	-1.8	-1.7	1.8	1.8	-1.7	-1.7	-1.4	1.1	1.4	2.1
Progressive ratio test 1 breakpoint	1.5	2.6	4.0	-1.8	-2.0	-1.7	-1.6	1.7	1.7	-1.6	-1.6	-1.2	0.9	1.3	2.0
Progressive ratio test 1 inactive lever presses	0.7	1.9	2.3	-1.4	-1.3	-1.4	-1.4	1.4	1.4	-1.4	-1.4	-1.3	1.3	1.2	1.5
Progressive ratio test 2 active lever presses	1.6	2.3	2.8	-1.6	-1.5	-1.6	-1.6	1.7	1.7	-1.5	-1.5	-1.5	1.3	1.3	1.3
Progressive ratio test 2 breakpoint	2.0	2.6	3.1	-1.7	-1.6	-1.7	-1.7	1.7	1.7	-1.6	-1.6	-1.6	1.4	1.4	1.4
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.3	-0.4	-0.3	-0.4	-0.4	0.5	0.5	-0.4	-0.3	-0.4	0.3	0.2	0.6
Incentive Sensitization - Responses	0.5	1.5	2.2	-1.2	-0.9	-1.2	-1.3	1.3	1.3	-1.3	-1.2	-1.5	1.4	1.2	0.7
Incentive Sensitization - Breakpoint	0.6	1.3	2.0	-1.1	-0.8	-1.1	-1.2	1.2	1.2	-1.2	-1.1	-1.4	1.4	1.1	0.7
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.7	0.5	0.4	0.5	0.6	-0.5	-0.5	0.6	0.5	0.8	-0.7	-0.6	-0.0
Progressive ratio	0.6	1.9	3.1	1.3	1.5	1.5	1.3	-1.3	-1.3	1.4	1.3	1.1	-1.7	-1.5	-1.0
Food seeking constrained by brief footshock	4.8	6.0	7.4	2.5	2.3	2.3	2.6	-2.5	-2.5	2.5	2.4	2.7	-2.4	-2.4	-2.0
Seeking ratio, punishment vs. effort	0.3	0.6	1.1	0.8	0.6	0.6	0.9	-0.9	-0.9	0.8	0.7	1.0	-0.4	-0.6	-0.6
Retroperitoneal fat weight	0.0	0.1	0.3	-0.3	-0.0	-0.1	-0.3	0.3	0.3	-0.3	-0.3	-0.5	0.5	0.3	-0.2
Reaction time number correct	2.2	7.7	9.1	-2.9	-2.9	-3.0	-2.8	2.7	2.7	-2.8	-2.8	-2.5	2.6	2.5	2.8
Reaction time mean minus median	0.0	0.1	0.2	0.3	0.4	0.2	0.2	-0.3	-0.3	0.1	0.2	-0.0	-0.1	-0.0	0.1
Reaction time mean minus median AUC	0.1	0.3	0.7	-0.4	-0.2	-0.5	-0.6	0.4	0.4	-0.6	-0.6	-0.8	0.5	0.7	0.8
Reaction time num false alarms	3.5	5.9	7.2	-2.4	-2.2	-2.5	-2.5	2.4	2.4	-2.5	-2.5	-2.6	2.7	2.6	1.9
Reaction time num false alarms AUC	2.2	5.0	5.9	-2.2	-2.0	-2.3	-2.3	2.2	2.2	-2.3	-2.2	-2.3	2.4	2.3	1.9
Reaction time trials correct on left	2.2	7.7	9.1	-2.9	-2.9	-3.0	-2.8	2.7	2.7	-2.8	-2.8	-2.5	2.6	2.5	2.8
Reaction time trials on left	2.2	7.6	9.1	-2.9	-2.9	-3.0	-2.8	2.7	2.7	-2.8	-2.8	-2.5	2.6	2.5	2.8
Reaction time mean	0.6	1.3	2.0	1.4	1.4	1.2	1.2	-1.3	-1.3	1.0	0.9	0.9	-0.9	-0.8	-1.0
Reaction time mean AUC	0.4	0.9	1.4	1.2	1.2	1.0	1.0	-1.1	-1.1	0.9	0.8	0.7	-0.7	-0.6	-0.7
Median of all reaction times	1.1	1.7	2.5	1.6	1.5	1.3	1.3	-1.5	-1.5	1.2	1.1	1.1	-1.0	-1.0	-1.3
Reaction time omissions	0.0	0.0	0.2	-0.0	-0.1	-0.1	-0.2	-0.0	-0.0	-0.3	-0.3	-0.2	0.3	0.4	-0.0
Reaction time false alarm rate	0.1	0.1	0.3	-0.2	-0.1	-0.2	-0.4	0.4	0.4	-0.4	-0.3	-0.6	0.6	0.5	0.1
Reaction time premature initiation rate	0.3	0.5	0.7	0.8	0.7	0.8	0.8	-0.9	-0.9	0.7	0.7	0.7	-0.5	-0.5	-0.4
Reaction time premature initiations	0.2	0.5	1.2	-0.7	-0.8	-0.7	-0.7	0.6	0.6	-0.7	-0.7	-0.6	0.8	0.8	1.1
Std. dev. reaction times	0.1	0.2	0.4	0.6	0.6	0.5	0.4	-0.5	-0.5	0.4	0.4	0.3	-0.5	-0.3	0.1
Reaction time trials completed	2.2	7.6	9.1	-2.9	-2.9	-3.0	-2.8	2.7	2.7	-2.8	-2.8	-2.5	2.6	2.5	2.8
Reaction time trials AUC	2.7	9.3	11.0	-3.1	-3.2	-3.3	-3.1	3.0	3.0	-3.1	-3.1	-2.8	2.9	2.8	3.0
Run reversals in cocaine runway, females	0.2	0.3	0.6	0.5	0.6	0.6	0.5	-0.5	-0.5	0.5	0.5	0.3	-0.8	-0.6	-0.2
Run reversals in cocaine runway, males	0.5	0.5	1.1	-0.7	-0.7	-0.7	-0.7	0.7	0.7	-0.7	-0.7	-0.6	1.1	0.9	0.0
Latency to leave start box in cocaine runway	0.2	0.2	0.5	-0.6	-0.3	-0.4	-0.5	0.3	0.3	-0.5	-0.5	-0.7	0.5	0.4	0.4
Latency to leave start box in cocaine runway, F	0.7	0.9	1.2	-1.1	-1.0	-0.9	-1.0	1.0	1.0	-0.9	-1.0	-1.0	0.6	0.8	1.1
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	0.1	0.4	0.2	0.1	-0.4	-0.4	0.1	0.1	-0.3	0.3	-0.0	-0.4
Std. dev. time between licks in bursts	0.0	0.1	0.2	-0.2	-0.3	-0.2	-0.1	-0.0	-0.0	-0.2	-0.3	-0.3	0.5	0.3	0.2
Total sessions with >9 infusions	3.4	4.2	5.5	-2.2	-2.3	-2.2	-2.1	2.1	2.1	-2.1	-2.1	-1.8	1.3	1.7	2.2
Short access day 1 total inactive lever presses	0.3	0.6	1.0	-0.7	-0.6	-0.7	-0.8	0.8	0.8	-0.8	-0.7	-0.9	1.0	0.8	0.7
Short access day 10 total inactive lever presses	0.2	1.3	2.0	1.3	1.4	1.2	1.2	-1.1	-1.1	1.1	1.2	0.9	-0.7	-1.0	-1.2
Short access day 1 total infusions	1.1	2.2	3.1	-1.6	-1.8	-1.6	-1.5	1.6	1.6	-1.5	-1.6	-1.3	0.9	1.2	1.4
Short access day 10 total infusions	2.6	4.3	5.5	-2.3	-2.3	-2.3	-2.1	2.1	2.1	-2.1	-2.2	-1.8	1.6	1.8	2.1
Short access total infusions	1.7	2.5	3.3	-1.7	-1.8	-1.7	-1.6	1.7	1.7	-1.6	-1.7	-1.3	1.1	1.3	1.5
Short access day 1 locomotion	2.2	3.6	4.6	-2.0	-2.1	-2.1	-2.0	2.0	2.0	-2.0	-2.1	-1.7	1.3	1.7	1.8
Short access day 10 total locomotion	0.0	0.1	0.3	0.1	-0.2	-0.3	-0.1	0.0	0.0	-0.2	-0.3	-0.0	0.5	0.4	0.2
Short access total locomotion	0.6	1.0	1.9	-0.9	-1.3	-1.1	-0.9	0.9	0.9	-1.0	-1.1	-0.5	0.6	0.8	1.4
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.3	-0.1	-0.3	-0.3	0.2	0.2	-0.3	-0.2	-0.4	0.4	0.2	0.4
Compulsive drug intake	0.3	0.5	1.3	-0.6	-0.7	-0.6	-0.6	0.5	0.5	-0.6	-0.6	-0.7	0.9	0.9	1.1
One hour access (shock baseline)	0.5	1.2	1.4	-1.2	-1.0	-1.2	-1.2	1.1	1.1	-1.2	-1.2	-1.1	1.1	0.9	0.8
Social response proportion	1.3	1.7	3.2	-1.2	-1.1	-1.4	-1.2	1.0	1.0	-1.4	-1.4	-1.5	1.8	1.5	0.9
Social responses	0.9	1.2	1.5	-1.1	-1.0	-1.1	-1.1	1.0	1.0	-1.1	-1.2	-1.2	1.2	1.2	1.0
Social time	2.6	4.1	4.8	2.1	2.1	2.1	2.1	-2.1	-2.1	2.1	2.1	1.8	-2.2	-2.0	-1.5
Soleus weight	0.2	0.5	1.3	-0.8	-0.3	-0.5	-0.7	0.6	0.6	-0.6	-0.6	-1.2	1.1	0.6	-0.0
Bone: stiffness	0.7	1.3	1.6	-1.2	-1.0	-1.1	-1.2	1.2	1.2	-1.1	-1.0	-1.2	1.3	1.0	1.1
Tibialis anterior weight	3.3	11.3	13.7	-3.6	-3.1	-3.2	-3.4	3.4	3.4	-3.4	-3.4	-3.7	3.6	3.4	2.6
Time to tail flick, vehicle, before self-admin	2.4	2.9	4.2	-1.7	-2.0	-1.8	-1.6	1.8	1.8	-1.6	-1.8	-1.2	1.2	1.6	2.1
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.2	-0.2	0.1	-0.1	-0.2	0.2	0.2	-0.2	-0.1	-0.5	0.1	-0.0	-0.0
Time to tail flick, test, before self-admin	0.5	0.5	1.1	0.8	0.4	0.7	0.8	-0.7	-0.7	0.8	0.6	1.1	-0.7	-0.6	-0.5
Time to tail flick, test, after self-admin	0.3	0.3	0.8	0.4	0.4	0.4	0.5	-0.4	-0.4	0.5	0.5	0.6	-0.9	-0.7	-0.6
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.3	0.3	0.5	0.3	0.2	-0.3	-0.3	0.3	0.4	0.0	-0.1	-0.3	-0.5
Delta time to tail flick, test, before/after SA	0.6	0.8	1.2	-1.1	-0.8	-1.0	-1.0	1.0	1.0	-0.9	-0.9	-1.0	0.6	0.7	0.5
Tibia length	0.2	0.6	1.6	-0.7	-0.8	-0.9	-0.8	0.6	0.6	-0.8	-0.8	-0.8	1.3	1.0	0.2
Ambulatory time before self-admin	0.0	0.0	0.0	0.0	0.1	0.1	0.0	-0.0	-0.0	0.0	0.1	-0.1	-0.0	0.1	-0.1
Ambulatory time after self-admin	0.3	0.5	1.1	0.6	0.6	0.7	0.7	-0.7	-0.7	0.7	0.7	0.7	-1.0	-0.8	-0.6
Bone: tissue strength	0.8	0.8	1.5	1.0	0.8	0.8	0.9	-0.9	-0.9	0.8	0.8	1.0	-1.2	-0.8	-0.4
Total heroin consumption	0.0	0.0	0.0	0.2	0.1	0.1	0.1	-0.1	-0.1	0.1	0.1	0.1	0.1	-0.0	0.1
Bone: trabecular number	0.0	0.1	0.2	0.1	0.2	0.2	0.2	-0.4	-0.4	0.1	0.0	-0.1	0.3	0.0	-0.4
Bone: trabecular spacing	0.0	0.0	0.1	-0.1	-0.1	-0.1	-0.2	0.3	0.3	-0.1	0.0	-0.0	-0.3	0.1	0.1
Bone: trabecular thickness	1.4	1.9	2.5	-1.4	-1.4	-1.4	-1.4	1.2	1.2	-1.4	-1.5	-1.5	1.6	1.5	1.0
Bone: trabecular tissue density	0.3	0.5	0.7	-0.6	-0.6	-0.7	-0.7	0.6	0.6	-0.7	-0.7	-0.8	0.7	0.7	0.6
Water consumed over 24 hours	0.1	0.2	1.0	0.4	0.1	0.1	0.3	-0.5	-0.5	0.2	0.0	0.3	0.4	0.2	-1.0
Number of responses in last shaping day	2.3	2.9	3.4	-1.8	-1.8	-1.8	-1.9	1.8	1.8	-1.8	-1.8	-1.7	1.4	1.6	1.4