Hub : Genes

Zfp207

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	isoform ratio	NM_001039020.2	0.05	0.05	1.9e-04	0.06	0.04	0.04	0.06	4.8e-06	1.4e-04	5.5e-05	6.3e-06
2	Brain	isoform ratio	NM_001393767.1	0.05	0.05	2.2e-04	0.06	0.04	0.04	0.06	6.0e-06	1.5e-04	5.3e-05	6.9e-06
3	Brain	intron excision ratio	chr10_65891761_65893962	0.02	0.02	8.0e-03	0.03	0.01	0.01	0.02	1.2e-03	1.3e-02	1.3e-02	2.7e-03
4	NAcc	intron excision ratio	chr10_65889356_65891117	0.2	0.02	3.4e-07	0.04	0.05	0.04	0.04	4.1e-07	6.1e-08	4.5e-07	4.9e-07
5	Liver	gene expression	Zfp207	0.04	0.03	1.4e-04	0.02	0.02	0.04	0.02	3.5e-03	2.3e-03	6.1e-05	4.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Bone: apparent density	1.8	3.4	4.2	-2.1	2.1	-2.1	-1.8	-1.0
Area under the delay curve	0.0	0.0	0.1	-0.3	0.3	-0.3	0.1	0.0
BMI with tail	0.6	2.2	8.3	-0.8	0.8	-0.8	-1.0	-2.9
BMI without tail	0.2	1.3	2.5	-1.1	1.1	-1.1	-1.6	-0.6
Body weight	2.1	9.2	10.8	-3.3	3.3	-3.3	-2.8	-2.4
Weight adjusted by age	0.2	0.7	1.4	0.7	-0.7	0.7	0.9	1.2
Bone surface	0.5	1.0	1.4	-1.2	1.2	-1.2	-0.7	-0.1
Bone volume	0.9	1.7	2.3	-1.5	1.5	-1.5	-1.3	-0.3
Breakpoint value in progressive ratio session	0.9	1.5	2.0	-1.4	1.4	-1.4	-1.1	0.5
Number of licking bursts	0.1	0.3	0.4	0.6	-0.6	0.6	0.3	0.4
Context. condit. distance diff. score	0.2	0.2	0.3	-0.6	0.6	-0.6	-0.4	-0.2
Locomotion velocity, session 1	1.2	1.3	1.8	-1.3	1.3	-1.3	-0.5	-1.1
Locomotion distance, session 1	0.0	0.1	0.2	-0.1	0.1	-0.1	0.2	0.5
Locomotion velocity, session 2	0.0	0.0	0.2	-0.1	0.1	-0.1	-0.1	0.4
Locomotion distance, session 2	0.4	0.5	0.8	-0.8	0.8	-0.8	-0.9	-0.3
Locomotion velocity, session 3	1.9	2.1	2.6	1.6	-1.6	1.6	1.5	0.9
Locomotion distance, session 3	0.4	0.5	0.7	0.7	-0.7	0.7	0.8	0.5
Stereotopy head waving bouts, day 3	0.2	0.3	1.2	0.3	-0.3	0.3	0.2	1.1
Stereotopy head waving duration, day 3	0.4	0.5	2.0	0.5	-0.5	0.5	0.2	1.4
Locomotion velocity, session 7	0.4	0.4	1.1	-0.3	0.3	-0.3	-0.8	1.0
Locomotion distance, session 7	0.2	0.3	0.8	-0.2	0.2	-0.2	-0.6	0.9
Stereotopy head waving bouts, day 7	0.6	0.7	0.8	-0.9	0.9	-0.9	-0.7	0.9
Stereotopy head waving duration, day 7	0.3	0.4	0.6	-0.6	0.6	-0.6	-0.4	0.8
Locomotion velocity, session 8	0.1	0.1	0.2	-0.3	0.3	-0.3	0.3	-0.4
Locomotion distance, session 8	0.1	0.2	0.2	-0.5	0.5	-0.5	-0.3	-0.2
Degree of sensitization distance	1.6	1.8	2.6	-1.4	1.4	-1.4	-1.6	0.1
Degree of sensitization stereotypy	0.7	0.8	1.1	-1.1	1.1	-1.1	-0.8	0.2
Conditioned locomotion	2.6	3.1	3.4	1.8	-1.8	1.8	1.6	1.6
Cocaine response after cond. corrected	0.8	1.2	1.7	-1.0	1.0	-1.0	-1.3	-1.1
Cocaine response after cond. not corrected	1.6	2.3	2.8	-1.5	1.5	-1.5	-1.7	-1.4
Cocaine response before conditioning	0.3	0.3	0.4	-0.7	0.7	-0.7	-0.6	0.2
Saline control response	0.3	0.5	1.5	0.6	-0.6	0.6	0.1	1.2
Bone: connectivity density	2.2	3.6	4.8	-2.2	2.2	-2.2	-1.6	-1.0
Bone: cortical apparent density	0.3	0.4	1.0	0.6	-0.6	0.6	-0.3	1.0
Bone: cortical area	1.9	3.0	5.2	1.8	-1.8	1.8	0.8	2.3
Bone: cortical porosity	0.1	0.2	0.3	0.4	-0.4	0.4	0.1	0.6
Bone: cortical porosity	0.2	0.2	0.2	0.5	-0.5	0.5	-0.1	0.5
Bone: cortical thickness	3.0	5.1	9.2	2.3	-2.3	2.3	0.9	3.0
Bone: cortical thickness	0.6	0.7	1.6	0.7	-0.7	0.7	-0.7	1.3
Bone: cortical tissue density	0.2	0.2	0.5	0.4	-0.4	0.4	-0.5	0.7
Condit. Reinf. active minus inactive responses	0.2	0.2	0.5	0.3	-0.3	0.3	-0.1	0.7
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.5	0.4	-0.4	0.4	0.1	0.7
Condit. Reinf. active responses	0.1	0.2	0.7	0.2	-0.2	0.2	-0.3	0.8
Condit. Reinf. inactive responses	0.0	0.0	0.0	0.1	-0.1	0.1	-0.0	0.2
Incentive salience index mean	0.1	0.2	0.5	0.3	-0.3	0.3	-0.2	0.7
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.3	0.3	-0.3	-0.5	0.2
Condit. Reinf. active minus inactive responses	0.2	0.3	0.4	0.7	-0.7	0.7	0.1	0.4
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	0.3	-0.3	0.3	0.0	-0.0
Condit. Reinf. active responses	0.3	0.4	0.6	0.8	-0.8	0.8	0.2	0.3
Condit. Reinf. inactive responses	0.2	0.3	0.4	0.6	-0.6	0.6	0.2	0.5
Condit. Reinf. lever presses	0.8	1.1	2.5	1.0	-1.0	1.0	0.3	1.6
Condit. Reinf. lever reinforcers received	0.4	0.6	0.9	0.9	-0.9	0.9	0.4	0.5
Conditioned reinforcement - actives	0.1	0.4	0.7	0.8	-0.8	0.8	0.4	0.2
Conditioned reinforcement - inactives	0.6	1.5	2.7	1.1	-1.1	1.1	1.1	1.6
Conditioned locomotion	1.0	1.4	1.9	1.4	-1.4	1.4	1.1	0.3
Patch foraging indifference point 0 sec	0.1	0.4	1.3	-0.4	0.4	-0.4	-0.6	1.1
Patch foraging indifference point AUC	0.9	2.1	2.8	1.7	-1.7	1.7	1.4	0.6
Delay disc. indifference point, 0s delay	0.5	0.5	0.7	0.8	-0.8	0.8	0.5	0.6
Delay disc. indifference point, 16s delay	0.1	0.1	0.2	-0.5	0.5	-0.5	-0.1	-0.3
Delay disc. indifference point, 2s delay	0.3	0.3	0.5	0.6	-0.6	0.6	0.7	0.1
Delay disc. indifference point, 24s delay	0.1	0.2	0.6	-0.3	0.3	-0.3	-0.5	0.8
Delay disc. indifference point, 4s delay	1.5	1.6	2.1	-1.4	1.4	-1.4	-1.3	-0.0
Delay disc. indifference point, 8s delay	0.3	0.5	0.7	-0.8	0.8	-0.8	-0.4	-0.7
Indifference point function ln k	2.5	7.5	8.9	-3.0	3.0	-3.0	-2.3	-2.4
Indifference point function log k	2.5	7.5	8.9	-3.0	3.0	-3.0	-2.3	-2.4
Patch foraging total patch changes 0 sec	0.1	0.4	1.4	-0.3	0.3	-0.3	-0.5	1.2
Patch foraging total patch changes 12 sec	0.2	0.3	1.4	0.2	-0.2	0.2	0.1	1.2
Patch foraging total patch changes 18 sec	0.7	1.5	4.1	1.1	-1.1	1.1	0.2	2.0
Patch foraging total patch changes 24 sec	0.3	1.2	1.4	1.1	-1.1	1.1	0.8	1.2
Patch foraging total patch changes 6 sec	1.6	2.7	4.2	1.6	-1.6	1.6	1.2	2.0
Patch foraging time to switch 0 sec	0.0	0.1	0.5	-0.2	0.2	-0.2	0.1	0.7
Patch foraging water rate 0 sec	0.1	0.6	0.7	0.8	-0.8	0.8	0.4	-0.8
Patch foraging water rate 12 sec	0.6	2.2	2.6	-1.6	1.6	-1.6	-1.2	-1.4
Patch foraging water rate 18 sec	1.4	3.2	3.5	-1.9	1.9	-1.9	-1.5	-1.8
Patch foraging water rate 24 sec	0.6	0.9	2.3	-0.7	0.7	-0.7	-0.8	-1.5
Patch foraging water rate 6 sec	0.2	0.3	1.6	0.1	-0.1	0.1	0.1	-1.2
Seeking ratio, delayed vs. immediate footshock	0.8	1.2	1.9	1.4	-1.4	1.4	-0.2	0.6
Distance traveled before self-admin	0.5	1.1	2.7	0.8	-0.8	0.8	1.0	1.6
Distance traveled after self-admin	0.1	0.2	0.5	0.4	-0.4	0.4	-0.5	0.7
Extensor digitorum longus weight	0.3	1.0	3.2	-0.8	0.8	-0.8	0.0	-1.8
Bone: elastic displacement	0.9	1.1	1.4	1.2	-1.2	1.2	0.2	1.2
Bone: elastic work	5.5	7.3	8.4	2.9	-2.9	2.9	1.9	2.8
Bone: endosteal estimation	0.1	0.2	0.7	0.1	-0.1	0.1	0.9	-0.0
Bone: endosteal perimeter	0.2	0.4	0.6	-0.8	0.8	-0.8	-0.0	-0.5
Epididymis fat weight	5.3	26.6	31.9	-5.6	5.6	-5.6	-5.3	-3.1
Delta time in closed arm before/after self-admin	0.2	0.2	0.8	0.2	-0.2	0.2	-0.0	-0.9
Delta time in open arm before/after self-admin	0.6	0.7	0.9	-0.9	0.9	-0.9	-0.8	-0.3
Diff in mean of infusions in LGA sessions	0.2	0.3	0.5	-0.7	0.7	-0.7	0.2	0.2
Delay discount exponential model param	0.1	0.1	0.2	0.5	-0.5	0.5	-0.0	-0.0
Extinction: sum of active levers before priming	0.2	0.2	0.3	-0.6	0.6	-0.6	0.3	0.2
Active lever presses in extinction session 6	0.4	0.4	1.7	-0.1	0.1	-0.1	0.5	1.3
Bone: final force	0.9	1.5	3.4	1.1	-1.1	1.1	0.2	1.8
Bone: final moment	0.8	1.2	2.4	1.1	-1.1	1.1	0.3	1.6
Food consumed during 24 hour testing period	0.2	0.3	0.8	0.5	-0.5	0.5	0.9	0.3
Glucose	1.1	1.7	2.3	1.5	-1.5	1.5	0.2	1.3
Heart weight	1.0	1.7	2.4	-1.5	1.5	-1.5	-1.1	-0.1
Delay discount hyperbolic model param	0.1	0.1	0.1	0.4	-0.4	0.4	-0.0	0.0
Intermittent access intake day 1-15 change	0.1	0.6	1.0	1.0	-1.0	1.0	0.4	-0.1
Intermittent access intake escalation	0.1	0.7	1.0	1.0	-1.0	1.0	0.4	-0.4
Intermittent access intake escalation 2	0.3	0.5	0.9	0.9	-0.9	0.9	0.1	-0.2
Intermitt. access day 1 inactive lever presses	0.0	0.6	1.0	0.8	-0.8	0.8	1.0	0.4
Intermitt. access day 15 inactive lever presses	0.8	4.3	6.4	2.0	-2.0	2.0	2.5	1.7
Intermitt. access escalation Index	0.7	2.2	4.6	-1.5	1.5	-1.5	-0.2	-2.1
Intermittent access day 1 total infusions	0.1	0.3	1.1	0.1	-0.1	0.1	0.6	1.0
Intermittent access day 15 total infusions	0.2	0.4	0.5	0.6	-0.6	0.6	0.7	0.4
Intermittent access terminal intake (last 3 days)	0.0	0.0	0.0	-0.1	0.1	-0.1	0.1	0.2
Intermittent access total infusions	0.1	0.1	0.3	0.3	-0.3	0.3	0.6	0.2
Intermittent access day 1 locomotion	0.7	1.3	1.8	1.1	-1.1	1.1	1.0	1.3
Intermittent access day 15 total locomotion	0.3	1.0	1.3	1.1	-1.1	1.1	1.1	0.3
Intermittent access total locomotion	0.7	0.8	1.1	1.0	-1.0	1.0	0.9	0.4
Intermittent access standard deviation	0.5	2.5	4.5	1.4	-1.4	1.4	1.3	2.1
Left kidney weight	0.0	0.3	0.9	-0.5	0.5	-0.5	-1.0	-0.3
Right kidney weight	0.0	0.3	0.3	-0.5	0.5	-0.5	-0.6	-0.5
Cocaine induced anxiety	0.1	0.3	0.4	-0.6	0.6	-0.6	-0.6	-0.2
Post-drug Anxiety	1.2	1.3	1.6	-1.3	1.3	-1.3	-1.2	0.8
Baseline Anxiety	0.3	0.6	1.9	0.6	-0.6	0.6	0.3	1.4
Tail length	0.6	3.1	3.7	-1.7	1.7	-1.7	-1.9	1.7
Length with tail	1.8	8.0	11.2	-3.4	3.4	-3.4	-2.5	0.1
Length without tail	0.8	4.3	5.9	-2.4	2.4	-2.4	-1.4	-1.4
Times rat made contact with spout	0.2	0.2	0.5	-0.3	0.3	-0.3	-0.7	-0.3
Lifetime Intake	0.2	0.2	0.8	0.3	-0.3	0.3	0.9	0.4
Liver weight, left	3.6	6.2	8.5	-2.9	2.9	-2.9	-2.1	-1.2
Liver weight, right	4.2	7.4	9.5	-3.1	3.1	-3.1	-2.9	-0.4
Locomotor activity	0.9	1.4	3.8	-0.7	0.7	-0.7	-2.0	1.2
Locomotor testing distance	0.8	1.9	5.7	-0.4	0.4	-0.4	-1.9	2.4
Locomotor testing rearing	0.2	0.9	2.5	0.6	-0.6	0.6	-1.0	1.6
Locomotion in novel chamber	0.8	1.1	1.6	1.2	-1.2	1.2	1.3	0.1
Locomotion in novel chamber post-restriction	0.7	2.0	3.1	-1.5	1.5	-1.5	-1.8	-0.8
Fecal boli incidents, locomotor time 1	0.1	0.2	0.7	-0.0	0.0	-0.0	-0.6	0.8
Change in fecal boli incidents, locomotor task	0.8	0.9	2.9	-0.7	0.7	-0.7	-0.4	-1.7
Time >=10cm from walls, locomotor time 1	1.4	1.8	2.9	1.7	-1.7	1.7	-0.1	-0.0
Bouts of movement, locomotor time 1	2.2	2.9	4.5	1.8	-1.8	1.8	2.1	-0.1
Total resting periods, locomotor time 1	2.8	3.2	4.8	1.9	-1.9	1.9	2.2	0.2
Rest time, locomotor task time 1	0.6	1.0	1.1	1.1	-1.1	1.1	1.0	0.7
Distance moved, locomotor task time 1	0.2	0.7	1.1	-0.9	0.9	-0.9	-1.0	0.3
Vertical activity count, locomotor time 1	0.3	2.2	3.8	-1.3	1.3	-1.3	-1.9	-1.3
Time >=10cm from walls, locomotor time 2	0.5	1.5	2.4	1.5	-1.5	1.5	-0.3	0.5
Bouts of movement, locomotor time 2	0.1	0.4	0.5	0.7	-0.7	0.7	0.5	-0.5
Total resting periods, locomotor time 2	0.1	0.5	0.6	0.8	-0.8	0.8	0.7	-0.4
Rest time, locomotor task time 2	0.8	1.3	1.5	1.2	-1.2	1.2	1.0	1.2
Distance moved, locomotor task time 2	0.2	0.3	0.4	-0.6	0.6	-0.6	-0.3	-0.1
Vertical activity count, locomotor time 2	0.3	0.6	1.4	-0.7	0.7	-0.7	-1.2	-0.5
Light reinforcement 1	0.4	1.8	3.8	-1.0	1.0	-1.0	-1.4	2.0
Light reinforcement 2	0.2	0.4	1.5	-0.3	0.3	-0.3	-0.4	1.2
Bone: marrow area	0.1	0.2	0.8	0.1	-0.1	0.1	0.9	0.1
Bone: maximum diameter	0.3	0.5	0.7	0.7	-0.7	0.7	0.9	0.5
Bone: maximum force	1.3	2.6	5.2	1.5	-1.5	1.5	0.6	2.3
Bone: maximum moment	1.2	2.2	3.9	1.5	-1.5	1.5	0.7	2.0
Mean time between licks in bursts	0.0	0.1	0.2	0.2	-0.2	0.2	0.0	0.4
Mean num. licks in bursts	0.2	0.6	0.7	-0.8	0.8	-0.8	-0.8	-0.4
Cd content in liver	0.1	0.1	0.1	-0.3	0.3	-0.3	0.2	-0.3
Co content in liver	0.2	0.3	0.3	0.5	-0.5	0.5	0.5	0.5
Cu content in liver	1.8	2.1	4.0	1.4	-1.4	1.4	2.0	1.0
Fe content in liver	1.6	1.9	2.6	-1.6	1.6	-1.6	-0.8	-1.1
K content in liver	0.9	0.9	4.0	-0.2	0.2	-0.2	0.5	-2.0
Mg content in liver	0.4	0.4	0.7	0.6	-0.6	0.6	0.8	-0.5
Mn content in liver	0.3	0.4	1.0	0.5	-0.5	0.5	1.0	-0.4
Na content in liver	1.7	1.9	5.0	-1.2	1.2	-1.2	-0.7	-2.2
Rb content in liver	0.3	0.3	1.2	0.4	-0.4	0.4	0.2	1.1
Se content in liver	1.5	1.7	2.9	1.2	-1.2	1.2	1.7	1.0
Sr content in liver	0.1	0.1	0.4	-0.3	0.3	-0.3	0.0	0.6
Zn content in liver	0.2	0.2	0.3	-0.5	0.5	-0.5	-0.4	0.1
Bone: minimum diameter	0.2	0.4	1.1	0.4	-0.4	0.4	0.7	1.1
Time in familiar zone, hab. session 1	0.1	0.1	0.4	0.1	-0.1	0.1	0.3	0.7
Time in novel zone, hab. session 1	0.1	0.1	0.4	-0.1	0.1	-0.1	-0.7	-0.3
Total zone transitions, hab. session 1	0.1	0.2	0.5	0.3	-0.3	0.3	0.0	0.7
Total locomotion distance, hab. session 1	0.2	0.3	1.3	0.3	-0.3	0.3	0.1	1.1
Locomotion velocity, hab. session 1	0.5	0.7	1.1	0.7	-0.7	0.7	0.8	1.1
Time in familiar zone, hab. session 2	0.2	0.3	0.8	-0.1	0.1	-0.1	0.9	-0.7
Time in novel zone, hab. session 2	0.6	0.7	2.5	0.4	-0.4	0.4	-0.6	1.6
Total zone transitions, hab. session 2	0.1	0.1	0.5	-0.0	0.0	-0.0	-0.3	0.7
Total locomotion distance, hab. session 2	0.7	0.9	2.8	0.8	-0.8	0.8	0.5	1.7
Locomotion velocity, hab. session 2	0.6	0.8	2.1	0.8	-0.8	0.8	0.5	1.5
Novel to familiar place preference ratio	0.6	0.7	1.9	-0.6	0.6	-0.6	-1.4	-0.8
Novelty place preference	1.2	1.5	3.5	-1.0	1.0	-1.0	-1.9	-0.9
Time in novel zone, NPP test	1.3	1.6	3.7	-1.1	1.1	-1.1	-1.9	-0.9
Total zone transitions, NPP test	0.2	0.3	1.3	0.1	-0.1	0.1	0.0	1.1
Total locomotion distance, NPP test	1.3	1.8	4.7	1.1	-1.1	1.1	0.8	2.2
Locomotion velocity, NPP test	1.4	2.0	4.6	1.2	-1.2	1.2	0.8	2.2
Intraocular pressure	1.0	1.6	3.7	1.2	-1.2	1.2	0.5	1.9
Delta distance traveled before/after self-admin	0.5	0.6	2.2	-0.4	0.4	-0.4	-1.5	-0.6
Delta ambulatory time before/after self-admin	0.8	1.3	3.2	-1.0	1.0	-1.0	-1.8	-0.8
Parametrial fat weight	6.0	14.2	18.3	-4.3	4.3	-4.3	-4.0	-0.5
Pavlov. Cond. lever latency	0.1	0.1	0.7	0.1	-0.1	0.1	0.0	-0.8
Pavlov. Cond. magazine entry latency	0.6	0.8	2.6	-0.7	0.7	-0.7	0.2	-1.6
Pavlov. Cond. change in total contacts	0.1	0.2	0.3	0.3	-0.3	0.3	0.5	0.5
Pavlov. Cond. index score	0.0	0.1	0.1	-0.3	0.3	-0.3	0.1	-0.2
Pavlov. Cond. latency score	0.1	0.1	0.1	-0.3	0.3	-0.3	0.1	-0.1
Pavlov. Cond. lever contacts	0.1	0.1	0.3	-0.3	0.3	-0.3	-0.2	0.5
Pavlov. Cond. magazine entry number	0.2	0.2	0.5	0.4	-0.4	0.4	-0.1	0.7
Pavlov. Cond. intertrial magazine entries	1.2	1.4	4.9	0.9	-0.9	0.9	0.2	2.2
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.1	0.1	-0.2	0.2	-0.2	0.3	-0.3
Pavlov. Cond. response bias	0.2	0.2	0.3	-0.6	0.6	-0.6	-0.1	-0.3
Pavlov. Cond. lever latency	0.9	1.3	1.9	-1.2	1.2	-1.2	-0.1	-1.4
Pavlov. Cond. magazine entry latency	0.3	0.4	0.8	-0.6	0.6	-0.6	-0.9	0.2
Pavlov. Cond. change in total contacts	0.2	0.4	0.7	0.8	-0.8	0.8	0.1	0.2
Pavlov. Cond. index score	0.3	0.5	1.2	0.7	-0.7	0.7	-0.1	1.1
Pavlov. Cond. latency score	0.5	0.7	1.3	0.9	-0.9	0.9	-0.0	1.1
Pavlov. Cond. lever contacts	0.5	0.7	1.4	0.8	-0.8	0.8	-0.3	1.2
Pavlov. Cond. magazine entry number	0.4	0.5	1.3	0.6	-0.6	0.6	1.1	-0.6
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.2	0.1	-0.1	0.1	-0.5	0.1
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.8	0.5	-0.5	0.5	-0.3	0.9
Pavlov. Cond. response bias	0.1	0.2	0.5	0.3	-0.3	0.3	-0.3	0.7
Time in closed arm before self-admin	2.0	3.5	7.0	-1.8	1.8	-1.8	-2.6	0.9
Time in closed arm after self-admin	0.3	0.3	1.2	-0.3	0.3	-0.3	-1.1	0.5
Time in open arm before self-admin	1.3	1.5	2.4	1.3	-1.3	1.3	1.6	-0.1
Time in open arm after self-admin	0.4	0.4	1.1	0.3	-0.3	0.3	1.0	-0.8
Bone: periosteal estimation	0.5	1.2	1.6	1.1	-1.1	1.1	1.1	1.3
Bone: periosteal perimeter	0.0	0.1	0.3	0.1	-0.1	0.1	0.0	0.5
Bone: post-yield work	0.2	0.3	0.8	-0.5	0.5	-0.5	-0.1	0.9
Progressive ratio test 1 active lever presses	0.5	0.8	1.5	0.8	-0.8	0.8	1.2	0.9
Progressive ratio test 1 breakpoint	0.5	0.9	1.7	0.8	-0.8	0.8	1.3	0.9
Progressive ratio test 1 inactive lever presses	1.5	3.9	4.9	2.2	-2.2	2.2	2.0	1.0
Progressive ratio test 2 active lever presses	1.7	2.3	3.1	1.7	-1.7	1.7	1.8	0.2
Progressive ratio test 2 breakpoint	1.9	2.4	3.4	1.7	-1.7	1.7	1.9	0.2
Progressive ratio test 2 inactive lever presses	0.5	1.5	2.2	1.5	-1.5	1.5	0.9	0.5
Incentive Sensitization - Responses	0.5	1.3	1.5	1.2	-1.2	1.2	1.2	-0.7
Incentive Sensitization - Breakpoint	0.5	1.1	1.4	1.2	-1.2	1.2	1.1	-0.6
Sum of active levers in priming session hrs 5-6	1.4	1.3	2.1	-1.4	1.4	-1.4	-0.6	-0.4
Progressive ratio	1.1	3.1	6.6	1.6	-1.6	1.6	1.3	2.6
Food seeking constrained by brief footshock	0.3	0.4	2.0	0.1	-0.1	0.1	-0.1	1.4
Seeking ratio, punishment vs. effort	0.6	1.4	1.8	-1.1	1.1	-1.1	-1.3	-1.4
Retroperitoneal fat weight	2.1	9.4	11.4	-3.4	3.4	-3.4	-3.3	-1.4
Reaction time number correct	0.4	1.4	2.2	-1.2	1.2	-1.2	-1.5	-0.7
Reaction time mean minus median	0.1	0.4	0.6	-0.8	0.8	-0.8	-0.2	-0.5
Reaction time mean minus median AUC	0.4	2.4	4.1	-1.5	1.5	-1.5	-1.0	-2.0
Reaction time num false alarms	1.9	3.2	4.1	2.0	-2.0	2.0	1.3	1.3
Reaction time num false alarms AUC	1.9	4.3	5.5	2.4	-2.4	2.4	1.7	1.4
Reaction time trials correct on left	0.4	1.4	2.2	-1.2	1.2	-1.2	-1.5	-0.7
Reaction time trials on left	0.4	1.5	2.2	-1.2	1.2	-1.2	-1.5	-0.8
Reaction time mean	0.8	1.8	2.4	-1.6	1.6	-1.6	-1.2	-0.6
Reaction time mean AUC	0.7	1.7	2.2	-1.5	1.5	-1.5	-1.1	-0.8
Median of all reaction times	1.1	1.8	2.2	-1.5	1.5	-1.5	-1.4	-0.6
Reaction time omissions	1.6	2.7	3.8	-1.6	1.6	-1.6	-1.3	-1.9
Reaction time false alarm rate	4.0	5.5	6.7	2.6	-2.6	2.6	2.2	1.6
Reaction time premature initiation rate	1.6	2.4	3.3	-1.8	1.8	-1.8	-0.5	-1.5
Reaction time premature initiations	1.2	3.6	4.5	-2.1	2.1	-2.1	-1.0	-1.8
Std. dev. reaction times	0.2	0.7	0.9	-1.0	1.0	-1.0	-0.4	-0.7
Reaction time trials completed	0.4	1.5	2.2	-1.2	1.2	-1.2	-1.5	-0.8
Reaction time trials AUC	0.4	1.4	2.2	-1.1	1.1	-1.1	-1.5	-0.8
Run reversals in cocaine runway, females	0.1	0.1	0.2	0.2	-0.2	0.2	0.5	0.4
Run reversals in cocaine runway, males	0.9	1.0	3.1	-0.6	0.6	-0.6	-0.8	1.8
Latency to leave start box in cocaine runway	0.3	0.4	1.2	-0.0	0.0	-0.0	1.1	0.9
Latency to leave start box in cocaine runway, F	0.3	0.4	1.9	0.1	-0.1	0.1	0.3	1.4
Latency to leave start box in cocaine runway, M	0.6	0.6	2.6	-0.2	0.2	-0.2	1.6	-0.5
Std. dev. time between licks in bursts	0.9	1.8	2.5	1.6	-1.6	1.6	0.8	0.9
Total sessions with >9 infusions	0.2	0.3	0.5	-0.6	0.6	-0.6	0.7	0.2
Short access day 1 total inactive lever presses	0.0	0.1	0.1	-0.3	0.3	-0.3	-0.4	-0.0
Short access day 10 total inactive lever presses	0.1	0.5	0.7	0.6	-0.6	0.6	0.8	-0.8
Short access day 1 total infusions	0.2	0.4	1.6	-0.2	0.2	-0.2	1.3	-0.7
Short access day 10 total infusions	0.0	0.1	0.3	-0.2	0.2	-0.2	0.5	0.1
Short access total infusions	0.3	0.4	1.2	0.3	-0.3	0.3	1.1	0.6
Short access day 1 locomotion	0.5	0.8	3.2	0.5	-0.5	0.5	1.8	-0.3
Short access day 10 total locomotion	0.6	2.6	3.6	1.7	-1.7	1.7	1.9	0.9
Short access total locomotion	1.6	2.5	5.2	1.5	-1.5	1.5	2.3	0.4
One hour access (0.3 mA shock)	1.0	1.2	1.5	1.2	-1.2	1.2	1.1	0.6
Compulsive drug intake	0.9	1.3	1.7	-1.3	1.3	-1.3	0.1	-1.2
One hour access (shock baseline)	0.5	1.2	1.7	1.3	-1.3	1.3	0.6	0.7
Social response proportion	2.0	2.5	3.0	-1.7	1.7	-1.7	-1.7	-0.9
Social responses	1.4	1.9	3.8	-1.0	1.0	-1.0	-1.6	1.9
Social time	0.5	0.8	1.0	-1.0	1.0	-1.0	-0.9	0.3
Soleus weight	1.7	5.0	5.9	-2.4	2.4	-2.4	-2.2	-1.5
Bone: stiffness	0.2	0.4	0.5	-0.7	0.7	-0.7	-0.7	0.1
Tibialis anterior weight	0.8	2.9	4.3	-2.1	2.1	-2.1	-1.1	-0.7
Time to tail flick, vehicle, before self-admin	0.0	0.0	0.0	-0.1	0.1	-0.1	0.1	0.2
Time to tail flick, vehicle, after self-admin	0.5	1.1	2.0	-1.0	1.0	-1.0	-1.4	0.6
Time to tail flick, test, before self-admin	0.2	0.2	1.0	0.1	-0.1	0.1	-1.0	0.1
Time to tail flick, test, after self-admin	0.4	0.4	1.1	0.4	-0.4	0.4	1.0	-0.7
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.9	-0.2	0.2	-0.2	-0.9	0.8
Delta time to tail flick, test, before/after SA	1.1	1.3	4.3	0.8	-0.8	0.8	2.1	-0.4
Tibia length	0.2	0.7	2.7	0.5	-0.5	0.5	-0.0	1.6
Ambulatory time before self-admin	0.1	0.2	0.8	0.1	-0.1	0.1	0.3	0.9
Ambulatory time after self-admin	1.0	1.6	3.4	-1.2	1.2	-1.2	-1.8	-0.2
Bone: tissue strength	0.1	0.1	0.2	0.4	-0.4	0.4	0.4	0.2
Total heroin consumption	1.5	1.7	2.4	-1.6	1.6	-1.6	-1.1	0.4
Bone: trabecular number	2.3	4.4	5.8	-2.4	2.4	-2.4	-1.8	-1.1
Bone: trabecular spacing	0.7	1.1	1.4	1.2	-1.2	1.2	1.0	-0.4
Bone: trabecular thickness	0.3	0.4	0.8	-0.6	0.6	-0.6	-0.9	0.5
Bone: trabecular tissue density	0.4	0.8	1.1	1.1	-1.1	1.1	0.3	0.7
Water consumed over 24 hours	0.3	0.7	1.8	-0.7	0.7	-0.7	-0.1	-1.3
Number of responses in last shaping day	1.0	1.3	2.6	0.7	-0.7	0.7	1.5	-1.6