Zfp110

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	Zfp110	0.45	0.16	3.1e-04	-0	0.06	0.06	0.01	7.6e-01	4.0e-04	3.0e-04	1.3e-01
2	NAcc	alternative TSS	NM_001024775.1	0.13	0.09	1.2e-03	-0	0.02	0.02	-0	4.8e-01	3.9e-04	1.1e-03	5.5e-01
3	NAcc	alternative TSS	XM_006228111.5	0.16	0.1	1.7e-04	-0	0.02	0.02	0	5.6e-01	4.6e-04	1.5e-03	1.8e-01
4	NAcc	gene expression	Zfp110	0.42	0.12	0.0e+00	0.1	0.18	0.18	0.16	2.5e-14	5.6e-26	4.4e-26	4.0e-24
5	Adipose	gene expression	Zfp110	0.13	0.07	1.2e-04	0	0.02	0.02	0	3.3e-01	1.5e-03	1.2e-03	2.1e-01
6	pVTA	gene expression	Zfp110	0.28	0.12	4.2e-08	0.01	0.1	0.07	0.04	4.9e-02	3.4e-08	1.6e-06	2.3e-04
7	PL	gene expression	Zfp110	0.42	0.13	5.4e-13	0.01	0.12	0.12	0.1	1.4e-02	1.1e-12	1.8e-13	1.5e-10
8	Brain	gene expression	Zfp110	0.39	0.15	3.3e-04	0.02	0.03	0.03	0.03	2.5e-03	5.5e-04	1.9e-03	4.0e-04
9	Liver	gene expression	Zfp110	0.19	0.1	4.6e-07	0.03	0.04	0.04	0.02	5.6e-04	5.5e-05	3.4e-05	9.5e-04
10	IC	gene expression	Zfp110	0.57	0.13	1.3e-11	0.06	0.25	0.26	0.26	1.3e-03	5.0e-11	3.2e-11	3.2e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.3	0.5	2.2	-1.5	-0.9	0.8	-0.3	0.1	-0.4	0.2	0.8	0.6	0.5
Area under the delay curve	0.8	1.0	1.7	-0.6	-0.8	0.8	-1.2	-0.5	-0.5	-1.3	-1.3	-1.1	-1.3
BMI with tail	0.3	1.0	2.9	0.7	0.2	-0.2	-0.1	1.7	1.0	-1.2	-1.7	-1.1	-0.5
BMI without tail	0.1	0.4	2.7	1.6	0.2	-0.0	-0.0	-0.0	-0.1	-0.7	-0.8	-0.4	-0.4
Body weight	0.2	0.9	2.8	1.1	0.1	0.0	0.9	-1.7	-1.0	0.8	1.2	0.5	0.5
Weight adjusted by age	0.7	1.1	2.9	-0.5	-1.5	1.5	-0.8	-1.3	-1.7	-0.4	0.7	-0.2	0.5
Bone surface	1.5	2.8	9.3	-1.3	-0.6	0.5	0.8	-1.2	-1.2	1.8	3.1	2.4	1.9
Bone volume	1.4	2.5	8.2	-1.1	-0.4	0.3	1.1	-0.9	-0.9	1.8	2.9	2.4	1.9
Breakpoint value in progressive ratio session	1.1	1.3	3.9	1.2	0.7	-0.6	-0.8	-0.3	0.6	-1.0	-1.9	-1.2	-2.0
Number of licking bursts	0.2	0.3	1.3	1.2	0.8	-0.8	0.4	0.3	0.3	-0.5	-0.3	0.1	-0.1
Context. condit. distance diff. score	0.6	0.7	2.6	-1.6	-1.1	1.1	-1.2	-0.6	-0.5	-0.1	0.0	-0.3	-0.3
Locomotion velocity, session 1	1.5	1.6	4.2	-1.5	-1.5	1.5	-1.4	-2.0	-1.5	-0.4	0.7	-0.5	-0.5
Locomotion distance, session 1	2.9	3.6	13.4	-1.8	-2.0	1.9	-1.3	-3.7	-2.7	0.1	1.8	-0.2	-0.3
Locomotion velocity, session 2	0.4	0.5	1.7	-1.3	-0.8	0.8	-0.8	-0.7	-0.6	-0.1	0.5	-0.0	-0.3
Locomotion distance, session 2	0.8	1.1	3.3	-0.6	-0.6	0.6	0.4	-1.6	-1.3	1.2	1.8	1.0	0.7
Locomotion velocity, session 3	0.2	0.2	0.5	-0.4	0.2	-0.2	0.2	0.4	0.4	0.7	0.5	0.6	0.3
Locomotion distance, session 3	1.9	2.1	9.0	-3.0	-1.8	1.7	-1.1	-0.6	-0.9	0.7	1.5	0.8	0.5
Stereotopy head waving bouts, day 3	0.6	0.7	2.6	1.6	1.0	-0.9	0.3	-0.4	0.4	-0.3	-0.9	-0.9	-0.9
Stereotopy head waving duration, day 3	0.8	1.0	3.5	1.9	1.1	-1.0	0.5	-0.6	0.3	-0.3	-1.0	-1.2	-1.1
Locomotion velocity, session 7	0.2	0.2	0.7	-0.2	-0.1	0.2	0.1	-0.8	-0.4	0.6	0.5	0.2	-0.1
Locomotion distance, session 7	0.1	0.2	0.3	-0.3	-0.6	0.6	-0.3	-0.5	-0.6	0.3	0.2	0.1	0.0
Stereotopy head waving bouts, day 7	0.4	0.5	1.2	-0.3	0.7	-0.8	0.8	-0.0	0.6	1.1	0.8	0.7	0.3
Stereotopy head waving duration, day 7	0.1	0.2	0.4	-0.0	0.5	-0.5	0.6	-0.3	0.2	0.6	0.5	0.3	0.1
Locomotion velocity, session 8	0.4	0.5	1.2	-0.7	-0.9	0.9	-0.8	-1.1	-0.8	-0.2	0.0	-0.3	-0.3
Locomotion distance, session 8	0.8	1.2	3.3	-1.8	-1.4	1.4	-1.1	-1.2	-1.1	0.3	0.8	0.1	0.0
Degree of sensitization distance	0.6	0.7	3.0	1.7	0.5	-0.4	0.2	-0.7	-0.2	-0.5	-0.9	-0.9	-0.8
Degree of sensitization stereotypy	0.6	0.7	2.6	-1.6	0.0	-0.1	0.2	0.6	0.6	0.9	1.1	1.0	0.8
Conditioned locomotion	0.6	0.7	1.2	-0.5	-0.9	1.0	-1.1	-1.1	-0.9	-0.5	-0.3	-0.8	-0.7
Cocaine response after cond. corrected	4.3	5.2	9.4	2.9	3.1	-3.0	2.5	2.9	2.7	1.3	-0.7	0.7	0.4
Cocaine response after cond. not corrected	1.8	2.1	4.3	1.9	1.9	-1.9	2.1	0.9	1.1	1.5	0.5	1.1	0.7
Cocaine response before conditioning	4.3	5.1	14.8	-2.3	-2.5	2.5	-1.2	-3.8	-3.2	0.1	2.5	0.7	0.6
Saline control response	1.1	1.5	5.3	-2.3	-1.5	1.4	-1.2	-1.1	-1.2	-0.2	1.2	0.6	0.2
Bone: connectivity density	0.4	0.7	3.6	-1.9	-0.8	0.7	-0.6	0.9	0.1	0.0	0.5	0.6	0.2
Bone: cortical apparent density	0.4	0.6	4.3	2.1	0.5	-0.4	0.8	0.4	-0.1	0.0	-0.5	0.1	-0.0
Bone: cortical area	1.1	1.7	3.4	-1.5	-1.8	1.8	-1.1	-1.4	-1.8	-0.7	1.0	-0.1	0.0
Bone: cortical porosity	0.2	0.2	0.6	0.2	0.5	-0.5	-0.0	0.6	0.8	0.3	-0.7	-0.3	-0.2
Bone: cortical porosity	0.4	0.5	1.0	0.6	0.9	-0.9	0.5	0.8	1.0	0.7	-0.3	0.1	0.1
Bone: cortical thickness	0.6	1.0	2.6	-0.0	-1.0	1.0	-1.1	-0.0	-0.7	-1.6	-1.1	-1.2	-1.0
Bone: cortical thickness	0.1	0.1	0.2	0.3	-0.3	0.4	0.1	-0.1	-0.4	0.4	0.4	0.5	0.3
Bone: cortical tissue density	0.5	0.7	4.6	2.1	0.7	-0.6	0.9	0.5	0.1	0.1	-0.4	0.2	0.0
Condit. Reinf. active minus inactive responses	0.7	0.8	3.2	1.8	1.2	-1.2	0.9	0.3	0.6	0.4	-0.5	0.2	-0.0
Condit. Reinf. active-inactive response ratio	0.6	0.6	2.1	0.9	0.6	-0.5	-0.2	0.8	0.7	-0.6	-1.5	-0.7	-0.7
Condit. Reinf. active responses	0.7	0.9	1.7	1.3	1.2	-1.2	1.3	-0.0	0.4	1.2	0.5	0.9	0.5
Condit. Reinf. inactive responses	1.1	1.4	4.3	-0.2	0.0	-0.0	1.0	-1.5	-0.8	1.6	2.1	1.4	0.9
Incentive salience index mean	0.3	0.3	1.5	1.2	0.5	-0.5	0.7	-0.6	-0.2	0.5	0.1	0.3	0.1
Condit. Reinf. lever presses	0.3	0.5	2.1	0.4	-0.5	0.5	0.3	-1.4	-1.1	0.4	0.5	0.2	0.1
Condit. Reinf. active minus inactive responses	1.6	2.1	5.3	-1.5	-1.2	1.1	-0.2	-2.3	-1.8	0.7	2.3	1.0	1.0
Condit. Reinf. active-inactive response ratio	1.5	1.7	5.5	-0.9	-0.4	0.4	0.8	-1.9	-1.1	1.5	2.4	1.2	1.1
Condit. Reinf. active responses	2.4	3.3	7.8	-2.0	-2.0	2.0	-1.2	-2.8	-2.5	0.1	2.1	0.7	0.7
Condit. Reinf. inactive responses	1.3	1.7	3.9	-1.2	-1.7	1.7	-2.0	-1.1	-1.5	-1.3	-0.1	-0.4	-0.3
Condit. Reinf. lever presses	0.7	1.0	2.3	-1.4	-1.2	1.2	-1.5	-0.8	-1.0	-0.9	0.1	-0.4	-0.3
Condit. Reinf. lever reinforcers received	2.8	3.9	8.4	-2.4	-2.1	2.0	-1.2	-2.9	-2.6	0.3	2.5	1.1	1.0
Conditioned reinforcement - actives	1.8	3.0	13.9	3.7	1.9	-1.7	2.2	0.7	1.0	1.6	0.3	0.4	0.8
Conditioned reinforcement - inactives	1.3	1.8	8.1	2.8	-0.2	0.4	1.0	-1.8	-1.5	1.1	1.1	0.3	1.2
Conditioned locomotion	1.3	1.7	8.3	2.9	1.4	-1.3	1.8	0.5	0.8	0.9	-0.0	0.1	0.4
Patch foraging indifference point 0 sec	1.8	3.3	6.3	-1.3	-2.1	2.1	-2.5	-1.2	-1.4	-2.1	-1.2	-2.0	-1.7
Patch foraging indifference point AUC	0.5	0.7	2.2	0.2	1.0	-1.1	0.7	1.5	1.4	-0.0	-0.5	-0.1	-0.1
Delay disc. indifference point, 0s delay	4.4	4.8	11.0	-3.0	-3.3	3.2	-2.3	-1.8	-2.6	-1.2	-0.0	-1.1	-0.3
Delay disc. indifference point, 16s delay	2.5	2.7	6.8	1.4	2.6	-2.6	1.4	1.6	2.3	0.2	-1.2	0.4	-0.9
Delay disc. indifference point, 2s delay	0.8	0.9	1.6	-0.4	-0.8	0.9	-1.3	-0.9	-0.7	-1.0	-1.0	-1.3	-1.1
Delay disc. indifference point, 24s delay	1.2	1.4	3.1	1.4	1.8	-1.7	1.0	1.1	1.5	0.1	-0.9	-0.3	-0.6
Delay disc. indifference point, 4s delay	0.1	0.1	0.3	-0.1	-0.3	0.3	0.1	-0.2	-0.4	0.0	0.3	0.4	0.5
Delay disc. indifference point, 8s delay	1.7	2.0	3.5	-0.7	-1.4	1.4	-1.7	-1.0	-0.9	-1.6	-1.5	-1.7	-1.9
Indifference point function ln k	3.0	5.2	21.3	-0.8	-2.3	2.4	-1.2	-4.6	-3.7	0.5	2.1	0.3	0.1
Indifference point function log k	3.0	5.2	21.3	-0.8	-2.3	2.4	-1.2	-4.6	-3.7	0.5	2.1	0.3	0.1
Patch foraging total patch changes 0 sec	1.7	3.3	5.9	-1.1	-2.1	2.1	-2.4	-1.1	-1.4	-2.2	-1.3	-2.0	-1.8
Patch foraging total patch changes 12 sec	0.2	0.3	1.6	-0.3	0.4	-0.4	0.2	1.3	0.9	-0.4	-0.5	-0.0	-0.1
Patch foraging total patch changes 18 sec	0.5	0.8	1.9	-1.3	-0.6	0.5	-1.1	0.5	0.2	-1.4	-0.8	-1.0	-0.8
Patch foraging total patch changes 24 sec	1.2	2.0	3.9	0.2	1.5	-1.6	2.0	1.9	1.8	1.2	0.8	1.1	1.0
Patch foraging total patch changes 6 sec	0.5	0.8	2.4	0.6	0.4	-0.4	-0.3	1.2	0.9	-1.1	-1.6	-1.0	-0.8
Patch foraging time to switch 0 sec	7.3	15.0	30.8	4.1	5.1	-5.0	4.1	5.5	5.1	1.7	-1.4	1.3	1.2
Patch foraging water rate 0 sec	2.4	4.9	8.6	-2.7	-2.9	2.8	-2.5	-2.9	-2.7	-1.1	0.7	-1.1	-0.9
Patch foraging water rate 12 sec	4.5	9.4	23.6	-2.4	-3.7	3.8	-3.5	-4.9	-4.2	-1.6	0.5	-1.5	-1.2
Patch foraging water rate 18 sec	2.7	4.1	10.5	-1.2	-2.4	2.4	-2.5	-3.2	-2.6	-1.2	0.0	-1.4	-1.2
Patch foraging water rate 24 sec	1.4	2.0	5.1	-1.6	-1.6	1.6	-1.5	-2.3	-1.8	-0.4	1.0	-0.4	-0.4
Patch foraging water rate 6 sec	2.4	3.5	10.8	-1.0	-0.9	0.9	0.2	-3.3	-2.3	1.6	3.1	1.6	1.2
Seeking ratio, delayed vs. immediate footshock	6.8	8.3	15.7	-3.5	-3.9	3.8	-4.0	-2.5	-2.9	-2.3	-0.4	-1.8	-1.1
Distance traveled before self-admin	6.5	8.5	20.3	-1.5	-4.4	4.5	-2.3	-3.8	-4.4	-0.9	0.6	-1.7	-0.0
Distance traveled after self-admin	8.8	10.8	21.0	-3.8	-4.6	4.5	-4.1	-2.5	-3.3	-2.8	-0.9	-2.6	-1.6
Extensor digitorum longus weight	0.0	0.2	0.4	-0.2	-0.4	0.4	-0.1	-0.3	-0.6	0.1	0.5	0.5	0.4
Bone: elastic displacement	1.2	1.4	3.6	-0.2	-0.7	0.7	-1.6	-0.5	-0.3	-1.9	-1.4	-1.6	-1.3
Bone: elastic work	1.8	2.3	4.2	-1.2	-2.0	2.1	-2.0	-1.8	-1.8	-1.5	-0.2	-0.8	-0.7
Bone: endosteal estimation	1.6	3.5	10.1	-1.9	-0.6	0.6	0.9	-2.3	-1.2	2.4	3.2	2.0	1.9
Bone: endosteal perimeter	0.9	1.9	5.0	-1.6	-1.2	1.1	0.1	-1.8	-1.4	1.0	2.2	1.0	1.0
Epididymis fat weight	0.8	2.8	5.0	1.8	2.2	-2.2	2.0	2.1	2.0	0.9	0.0	0.7	1.0
Delta time in closed arm before/after self-admin	0.3	0.2	1.9	-1.4	-0.5	0.4	-0.2	0.1	-0.1	-0.3	0.1	-0.1	0.0
Delta time in open arm before/after self-admin	1.0	1.0	4.1	2.0	-0.2	0.3	0.9	-1.3	-1.0	1.2	0.6	0.2	0.5
Diff in mean of infusions in LGA sessions	1.9	2.3	3.6	0.0	-1.7	1.8	-1.9	-1.9	-1.7	-1.4	-0.9	-1.5	-1.1
Delay discount exponential model param	0.7	0.8	1.4	0.3	0.7	-0.8	1.0	0.5	0.5	1.2	1.2	1.1	1.2
Extinction: sum of active levers before priming	0.2	0.3	1.9	-1.4	-0.5	0.4	-0.1	0.2	-0.2	0.0	0.3	0.2	0.1
Active lever presses in extinction session 6	4.6	4.6	8.0	2.3	2.8	-2.8	2.7	2.4	2.4	1.8	0.4	1.3	1.0
Bone: final force	1.1	1.7	3.8	-0.8	-1.2	1.2	0.0	-1.9	-1.9	0.5	1.9	1.1	1.0
Bone: final moment	1.6	2.6	5.8	-1.4	-1.7	1.7	-0.3	-2.4	-2.3	0.5	2.2	1.2	1.0
Food consumed during 24 hour testing period	0.5	0.7	3.6	0.6	-0.6	0.7	-0.1	-1.9	-1.4	-0.2	0.2	-0.3	-0.4
Glucose	1.2	1.8	4.8	-0.1	-0.9	0.9	-1.4	-0.3	-0.4	-1.9	-2.2	-2.0	-1.5
Heart weight	0.4	0.7	4.1	2.0	0.5	-0.3	0.7	-1.1	-0.7	0.2	-0.1	0.1	0.1
Delay discount hyperbolic model param	1.0	1.1	1.8	0.4	1.0	-1.0	1.3	0.6	0.7	1.3	1.3	1.3	1.2
Intermittent access intake day 1-15 change	0.7	1.5	8.1	2.8	1.1	-1.0	1.6	-0.4	0.0	1.0	0.5	0.7	0.7
Intermittent access intake escalation	1.3	2.7	12.7	3.6	1.6	-1.4	2.3	-0.3	0.2	1.5	0.7	0.8	1.1
Intermittent access intake escalation 2	0.5	0.6	1.4	1.1	-0.7	0.8	-0.4	-1.2	-1.1	-0.4	-0.1	-0.5	-0.2
Intermitt. access day 1 inactive lever presses	1.2	4.6	19.5	4.4	2.1	-1.8	3.0	-0.5	0.6	2.8	0.5	0.7	0.6
Intermitt. access day 15 inactive lever presses	2.1	4.3	10.8	3.3	1.9	-1.7	3.0	-0.0	0.4	2.9	1.5	1.8	1.7
Intermitt. access escalation Index	0.5	0.6	1.6	0.7	0.5	-0.5	-0.1	0.5	0.5	-1.3	-1.0	-1.2	-0.9
Intermittent access day 1 total infusions	0.6	1.0	3.2	1.8	0.9	-0.8	1.2	0.4	0.5	1.4	0.7	0.5	1.0
Intermittent access day 15 total infusions	2.8	4.2	21.0	4.6	2.4	-2.2	2.5	-0.0	0.9	1.6	0.2	0.5	0.6
Intermittent access terminal intake (last 3 days)	1.8	2.4	12.6	3.5	1.7	-1.5	1.7	-0.2	0.5	1.5	0.3	0.5	0.6
Intermittent access total infusions	2.5	3.0	13.1	3.6	1.7	-1.5	2.0	-0.1	0.6	2.0	0.8	0.9	1.1
Intermittent access day 1 locomotion	1.0	1.3	4.5	2.1	1.0	-0.9	1.6	-0.5	0.2	1.5	0.7	0.7	0.8
Intermittent access day 15 total locomotion	1.0	1.9	6.8	2.6	-0.8	1.1	0.2	-2.4	-1.8	0.3	-0.0	-1.0	-0.3
Intermittent access total locomotion	2.0	2.4	10.0	3.2	0.7	-0.5	1.9	-1.3	-0.6	2.0	1.2	0.7	1.2
Intermittent access standard deviation	0.5	1.1	3.4	1.8	0.1	0.1	-0.7	-0.5	-0.1	-0.9	-1.4	-1.5	-1.3
Left kidney weight	1.5	6.9	24.5	0.3	-1.1	1.2	1.1	-5.0	-3.3	2.9	3.8	2.2	1.5
Right kidney weight	1.3	5.8	16.5	1.2	-0.1	0.2	1.7	-4.1	-2.6	2.9	3.6	2.4	1.7
Cocaine induced anxiety	0.4	0.6	1.1	0.4	0.3	-0.3	0.9	-0.9	-0.5	1.0	0.9	1.1	0.6
Post-drug Anxiety	1.8	1.9	4.5	0.4	1.6	-1.6	1.8	0.4	1.0	1.8	1.0	2.1	0.9
Baseline Anxiety	0.5	0.6	2.9	-1.7	0.2	-0.3	-0.6	0.7	0.8	-0.4	-0.6	0.2	-0.8
Tail length	0.8	2.9	13.1	0.6	-0.6	0.8	0.2	-3.6	-2.4	1.3	2.4	1.3	0.6
Length with tail	0.8	3.6	9.9	0.8	0.6	-0.5	1.7	-2.7	-1.4	2.5	3.1	2.1	1.6
Length without tail	1.8	5.8	12.9	2.0	2.7	-2.7	3.6	0.2	1.0	3.0	2.5	2.4	2.1
Times rat made contact with spout	0.2	0.2	0.6	-0.8	-0.5	0.4	-0.7	0.3	-0.0	-0.6	-0.4	-0.2	-0.4
Lifetime Intake	2.0	2.4	9.6	3.1	1.6	-1.4	1.9	0.2	0.6	1.8	0.8	0.9	1.1
Liver weight, left	0.4	0.6	1.5	0.8	0.1	-0.0	0.6	-1.2	-0.8	0.8	1.0	0.9	0.6
Liver weight, right	0.4	0.6	1.2	-0.1	-0.9	1.0	-1.1	-0.7	-0.8	-0.9	-0.5	-0.9	-0.5
Locomotor activity	0.1	0.2	0.6	-0.1	-0.1	0.1	-0.3	0.7	0.4	-0.4	-0.8	-0.2	-0.3
Locomotor testing distance	0.3	0.5	1.2	0.4	0.8	-0.9	0.8	1.1	0.9	0.5	-0.1	0.7	0.4
Locomotor testing rearing	0.1	0.3	1.5	-1.2	-0.3	0.3	-0.1	-0.3	-0.2	0.4	0.7	0.3	0.2
Locomotion in novel chamber	0.9	1.1	3.8	-1.9	0.0	-0.2	-1.4	0.2	0.6	-1.5	-1.0	-0.3	-1.2
Locomotion in novel chamber post-restriction	0.9	1.4	4.1	-2.0	-0.2	0.1	-1.7	0.3	0.2	-1.9	-1.1	-0.8	-1.3
Fecal boli incidents, locomotor time 1	0.5	0.7	1.3	-0.4	-1.1	1.2	-1.0	-1.0	-1.1	-0.1	0.2	-0.7	-0.3
Change in fecal boli incidents, locomotor task	1.4	1.4	3.1	-1.0	-0.1	0.1	-1.3	0.5	0.6	-1.7	-1.8	-1.3	-1.7
Time >=10cm from walls, locomotor time 1	0.5	0.5	1.1	0.7	1.0	-1.0	0.5	0.9	1.1	0.2	-0.5	0.5	-0.2
Bouts of movement, locomotor time 1	4.7	5.3	10.3	-2.0	-3.2	3.2	-2.3	-2.8	-2.9	-1.7	-0.3	-1.5	-1.0
Total resting periods, locomotor time 1	2.6	2.9	4.4	-2.1	-2.1	2.0	-1.9	-2.0	-1.8	-1.5	-0.6	-1.1	-1.3
Rest time, locomotor task time 1	0.4	0.4	1.2	-1.1	-0.1	-0.0	0.3	-0.5	-0.5	0.5	1.0	1.0	0.6
Distance moved, locomotor task time 1	0.3	0.4	1.0	0.5	0.1	-0.0	-0.4	0.5	0.4	-0.9	-1.0	-0.9	-0.6
Vertical activity count, locomotor time 1	1.9	4.5	7.9	-1.1	-2.4	2.5	-2.8	-0.7	-1.3	-2.7	-2.0	-2.6	-1.9
Time >=10cm from walls, locomotor time 2	0.8	1.2	3.2	0.1	1.5	-1.6	0.8	1.7	1.8	0.2	-0.4	0.8	-0.0
Bouts of movement, locomotor time 2	0.4	0.6	3.7	-1.9	-0.5	0.4	-1.0	-0.2	-0.1	-0.6	-0.2	0.5	-0.4
Total resting periods, locomotor time 2	0.5	1.0	6.0	-2.4	-0.8	0.6	-1.2	-0.3	-0.3	-0.8	-0.1	0.5	-0.4
Rest time, locomotor task time 2	2.0	2.5	9.0	-3.0	-1.9	1.8	-1.8	-1.1	-1.3	-1.3	-0.1	-0.4	-0.8
Distance moved, locomotor task time 2	0.1	0.1	0.7	0.8	0.1	-0.1	0.2	0.5	0.1	0.1	0.1	-0.1	0.6
Vertical activity count, locomotor time 2	0.6	0.9	2.2	-0.1	-1.4	1.5	-1.3	-0.2	-0.9	-1.0	-0.3	-0.9	0.0
Light reinforcement 1	0.9	2.3	4.3	-2.0	-2.1	2.0	-2.0	-1.4	-1.6	-1.1	0.1	-0.7	-0.5
Light reinforcement 2	0.3	0.5	1.2	0.6	0.5	-0.5	-0.2	1.1	0.8	-0.8	-1.0	-0.5	-0.2
Bone: marrow area	1.6	3.6	10.2	-1.9	-0.6	0.6	0.9	-2.3	-1.2	2.5	3.2	2.1	1.9
Bone: maximum diameter	0.6	1.1	2.3	-1.2	-1.5	1.5	-0.5	-1.2	-1.5	-0.2	1.1	0.1	0.1
Bone: maximum force	1.3	2.3	5.1	-1.2	-1.7	1.6	-0.4	-2.2	-2.3	0.3	1.9	1.0	0.9
Bone: maximum moment	1.9	3.3	7.0	-1.7	-2.1	2.1	-0.8	-2.6	-2.6	0.3	2.1	1.0	0.9
Mean time between licks in bursts	0.4	0.9	1.9	-0.0	-0.9	0.9	-1.2	0.0	-0.4	-1.4	-1.3	-1.2	-1.1
Mean num. licks in bursts	0.3	0.5	2.2	-1.5	-1.0	0.9	-0.7	-0.1	-0.4	0.3	0.2	0.0	-0.0
Cd content in liver	0.5	0.6	1.9	0.1	0.1	-0.1	0.8	-1.1	-0.7	0.9	1.4	0.5	0.6
Co content in liver	0.4	0.4	0.9	1.0	0.2	-0.2	0.5	-0.9	-0.7	0.7	0.7	0.6	0.4
Cu content in liver	2.0	2.4	5.1	0.9	1.5	-1.5	2.3	-0.1	0.5	2.2	1.9	1.8	1.3
Fe content in liver	1.4	1.7	3.3	1.8	1.6	-1.5	1.8	0.7	0.8	1.3	0.7	1.1	0.8
K content in liver	0.1	0.1	0.3	-0.4	0.3	-0.3	0.4	-0.1	0.2	0.5	0.5	-0.0	-0.1
Mg content in liver	0.9	0.9	1.9	0.6	1.4	-1.4	1.1	1.0	1.2	0.9	0.2	0.4	0.0
Mn content in liver	0.5	0.6	1.3	0.7	1.1	-1.1	0.9	0.7	1.1	0.6	-0.1	0.3	0.1
Na content in liver	0.6	0.7	2.3	-0.1	1.0	-1.0	0.2	1.2	1.5	0.1	-0.8	-0.3	-0.5
Rb content in liver	1.9	2.2	6.1	-0.1	1.1	-1.2	1.7	-1.4	0.1	2.5	2.3	1.5	1.1
Se content in liver	1.0	1.1	3.1	0.5	0.7	-0.7	-0.3	1.5	1.4	-0.8	-1.8	-1.0	-1.0
Sr content in liver	6.4	5.5	10.9	-1.5	-2.2	2.2	-3.2	0.2	-0.6	-3.3	-3.0	-2.8	-2.3
Zn content in liver	3.0	3.3	6.2	2.1	2.5	-2.5	2.2	2.2	2.2	1.2	-0.3	0.6	0.5
Bone: minimum diameter	2.3	4.2	8.2	-2.9	-2.3	2.2	-1.0	-2.7	-2.5	0.5	2.7	0.8	0.9
Time in familiar zone, hab. session 1	5.3	5.1	11.5	-2.4	-3.0	3.0	-1.7	-3.4	-3.1	-0.3	1.6	-0.0	0.3
Time in novel zone, hab. session 1	4.7	4.7	10.2	2.3	3.0	-3.0	1.9	3.2	2.9	0.6	-0.9	0.6	0.2
Total zone transitions, hab. session 1	1.9	2.7	6.1	-2.5	-1.7	1.7	-0.9	-2.2	-1.8	1.1	2.0	0.8	0.5
Total locomotion distance, hab. session 1	2.2	3.1	5.9	-2.4	-2.4	2.4	-2.2	-1.9	-2.0	-0.7	0.6	-0.7	-0.6
Locomotion velocity, hab. session 1	1.4	2.0	3.6	-1.9	-1.9	1.9	-1.7	-1.6	-1.6	-0.4	0.5	-0.5	-0.5
Time in familiar zone, hab. session 2	1.2	1.2	2.8	0.8	0.7	-0.7	1.2	-0.2	-0.1	1.5	1.6	1.7	1.3
Time in novel zone, hab. session 2	0.4	0.4	1.0	0.0	0.5	-0.5	0.1	1.0	0.9	-0.4	-0.9	-0.6	-0.4
Total zone transitions, hab. session 2	3.7	4.7	11.0	-3.0	-2.6	2.6	-1.7	-3.3	-2.7	0.1	1.9	-0.2	-0.3
Total locomotion distance, hab. session 2	3.2	4.2	7.6	-2.4	-2.7	2.7	-2.8	-1.7	-2.0	-1.7	-0.2	-1.5	-1.3
Locomotion velocity, hab. session 2	3.7	4.9	8.9	-2.6	-2.9	2.9	-3.0	-1.9	-2.1	-1.9	-0.4	-1.8	-1.4
Novel to familiar place preference ratio	1.0	1.1	1.8	-1.2	-1.1	1.1	-1.3	-1.2	-0.9	-1.2	-0.3	-0.9	-0.6
Novelty place preference	0.7	0.7	1.9	-1.0	-0.9	0.9	-1.0	-1.4	-0.9	-0.8	0.0	-0.6	-0.3
Time in novel zone, NPP test	0.5	0.5	1.5	-0.8	-0.7	0.7	-0.8	-1.2	-0.8	-0.6	0.1	-0.4	-0.2
Total zone transitions, NPP test	0.8	1.2	2.4	-1.3	-1.5	1.5	-1.1	-1.4	-1.4	-0.4	0.3	-0.5	-0.4
Total locomotion distance, NPP test	1.7	2.3	4.4	-1.4	-1.9	1.9	-2.1	-1.3	-1.5	-1.6	-0.4	-1.5	-1.1
Locomotion velocity, NPP test	2.2	3.1	5.5	-1.7	-2.2	2.2	-2.3	-1.6	-1.8	-1.6	-0.3	-1.5	-1.1
Intraocular pressure	0.2	0.3	1.1	0.2	0.5	-0.5	0.5	0.5	0.4	0.6	0.5	1.0	0.5
Delta distance traveled before/after self-admin	1.4	1.4	2.8	-1.0	-0.3	0.3	-1.7	0.5	0.6	-1.7	-1.6	-1.3	-1.6
Delta ambulatory time before/after self-admin	1.2	1.5	3.3	-0.7	-0.5	0.5	-1.7	0.1	0.2	-1.8	-1.7	-1.5	-1.8
Parametrial fat weight	1.2	2.8	8.0	0.5	-0.4	0.5	-1.0	1.3	0.6	-2.1	-2.8	-2.5	-2.2
Pavlov. Cond. lever latency	0.0	0.0	0.1	0.0	0.3	-0.3	0.0	0.3	0.3	-0.1	0.1	0.1	0.1
Pavlov. Cond. magazine entry latency	0.4	0.5	1.6	-0.1	-0.0	-0.0	-0.5	1.3	0.6	-0.8	-1.0	-0.6	-0.6
Pavlov. Cond. change in total contacts	0.1	0.1	0.2	-0.3	-0.4	0.4	-0.4	-0.0	-0.1	-0.3	-0.5	-0.5	-0.4
Pavlov. Cond. index score	0.2	0.2	0.5	-0.2	-0.3	0.3	-0.5	0.3	0.0	-0.5	-0.7	-0.6	-0.5
Pavlov. Cond. latency score	0.2	0.2	0.6	-0.1	-0.4	0.4	-0.6	0.2	-0.1	-0.6	-0.8	-0.7	-0.6
Pavlov. Cond. lever contacts	0.0	0.0	0.1	0.1	0.1	-0.1	0.2	0.0	0.0	0.3	-0.0	0.1	0.0
Pavlov. Cond. magazine entry number	0.2	0.2	0.6	0.8	0.4	-0.4	0.6	-0.8	-0.2	0.4	0.4	0.2	0.3
Pavlov. Cond. intertrial magazine entries	0.7	0.8	2.2	-1.0	-1.1	1.1	-1.0	-1.5	-1.1	-0.5	0.4	-0.3	-0.0
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.6	-0.1	-0.3	0.3	-0.5	0.3	0.1	-0.5	-0.7	-0.6	-0.5
Pavlov. Cond. response bias	0.1	0.1	0.7	-0.2	0.2	-0.2	0.1	0.9	0.5	0.3	-0.1	0.2	0.1
Pavlov. Cond. lever latency	2.8	3.8	9.6	2.2	2.2	-2.1	3.1	0.5	1.1	2.4	1.3	1.8	1.5
Pavlov. Cond. magazine entry latency	1.1	1.3	2.8	-0.7	-0.5	0.5	-1.6	0.7	0.2	-1.7	-1.7	-1.4	-1.3
Pavlov. Cond. change in total contacts	1.9	3.1	6.3	-2.5	-2.4	2.3	-2.4	-1.4	-1.7	-1.4	0.1	-0.8	-0.6
Pavlov. Cond. index score	1.5	2.0	5.0	-1.8	-1.6	1.5	-2.2	-0.3	-0.8	-1.8	-0.9	-1.2	-1.1
Pavlov. Cond. latency score	1.7	2.2	5.4	-1.4	-1.4	1.4	-2.3	0.1	-0.5	-2.0	-1.4	-1.6	-1.3
Pavlov. Cond. lever contacts	2.5	3.4	8.4	-2.3	-2.1	2.1	-2.9	-0.7	-1.2	-2.2	-0.9	-1.6	-1.3
Pavlov. Cond. magazine entry number	0.6	0.7	1.5	0.8	0.6	-0.5	1.2	-0.8	-0.1	1.2	1.1	0.8	0.7
Pavlov. Cond. intertrial magazine entries	1.6	2.4	8.4	-0.4	-0.1	0.1	1.3	-2.0	-1.2	1.7	2.9	1.7	1.7
Pavlov. Cond. lever-magazine prob. diff.	1.4	1.9	4.7	-1.7	-1.5	1.4	-2.2	-0.2	-0.7	-1.8	-0.9	-1.2	-1.0
Pavlov. Cond. response bias	1.9	2.6	5.9	-2.4	-2.1	2.0	-2.4	-1.0	-1.4	-1.6	-0.1	-0.9	-0.8
Time in closed arm before self-admin	0.7	0.9	6.5	2.6	0.2	-0.0	0.3	-1.1	-0.6	0.5	0.0	-0.4	-0.0
Time in closed arm after self-admin	0.1	0.2	0.5	0.4	0.7	-0.7	0.1	-0.1	0.4	0.4	0.1	0.4	-0.0
Time in open arm before self-admin	1.6	1.7	9.7	-3.1	-0.9	0.7	-1.4	1.0	0.3	-1.6	-0.6	-0.4	-0.5
Time in open arm after self-admin	0.2	0.2	1.4	-1.2	-0.6	0.6	-0.3	0.2	-0.2	-0.3	-0.0	-0.1	-0.1
Bone: periosteal estimation	1.4	3.0	7.1	-2.4	-1.7	1.6	-0.2	-2.1	-1.9	1.1	2.7	1.3	1.2
Bone: periosteal perimeter	1.4	2.4	7.0	-2.2	-1.4	1.3	-0.0	-1.2	-1.4	0.8	2.7	1.5	1.5
Bone: post-yield work	1.7	2.5	5.9	-0.2	0.7	-0.7	1.8	-0.5	-0.2	2.3	2.4	2.2	2.0
Progressive ratio test 1 active lever presses	0.6	0.8	1.8	0.4	-1.1	1.2	0.1	-1.0	-1.3	0.6	0.9	0.3	1.0
Progressive ratio test 1 breakpoint	0.6	0.8	1.8	0.3	-1.2	1.2	0.1	-1.0	-1.3	0.6	0.8	0.2	0.9
Progressive ratio test 1 inactive lever presses	2.0	2.8	7.2	2.7	0.6	-0.4	2.2	-0.8	-0.6	2.7	1.6	1.4	1.8
Progressive ratio test 2 active lever presses	2.6	3.1	14.3	3.8	1.9	-1.7	2.3	0.5	0.9	1.7	0.4	0.5	0.7
Progressive ratio test 2 breakpoint	3.0	3.5	15.1	3.9	2.1	-1.8	2.4	0.5	1.0	1.8	0.5	0.7	0.9
Progressive ratio test 2 inactive lever presses	2.2	3.5	11.9	3.4	0.7	-0.5	2.4	-1.2	-0.8	2.7	1.7	1.2	1.7
Incentive Sensitization - Responses	3.8	5.3	21.8	4.7	2.7	-2.5	3.1	0.4	1.1	2.1	0.7	0.9	0.9
Incentive Sensitization - Breakpoint	4.0	5.2	20.7	4.5	2.8	-2.6	3.0	0.6	1.3	2.0	0.5	0.8	0.8
Sum of active levers in priming session hrs 5-6	1.3	1.2	2.0	0.1	-0.9	1.0	-1.1	-1.4	-1.0	-1.2	-1.0	-1.4	-1.3
Progressive ratio	1.1	1.7	4.1	-1.8	-2.0	2.0	-1.6	-0.7	-1.2	-0.8	-0.1	-0.5	-0.4
Food seeking constrained by brief footshock	28.0	34.3	71.4	-5.7	-8.4	8.4	-6.9	-5.5	-6.8	-4.9	-0.9	-4.0	-2.1
Seeking ratio, punishment vs. effort	1.9	2.8	6.0	-1.0	-2.2	2.2	-1.5	-2.5	-2.4	-1.2	0.2	-1.1	-0.2
Retroperitoneal fat weight	2.6	11.0	30.8	3.0	2.8	-2.7	0.7	5.5	4.3	-2.3	-4.7	-2.7	-1.7
Reaction time number correct	1.1	2.2	5.0	-2.2	-1.8	1.7	-2.2	-0.4	-0.8	-1.5	-0.6	-1.2	-1.1
Reaction time mean minus median	0.2	0.6	1.3	0.6	0.9	-0.9	1.1	0.6	0.8	1.1	0.4	0.4	0.5
Reaction time mean minus median AUC	0.4	1.1	2.1	0.2	1.2	-1.2	1.5	1.2	1.2	1.2	0.7	0.7	0.8
Reaction time num false alarms	0.2	0.2	0.4	0.5	-0.4	0.5	-0.5	-0.5	-0.4	-0.2	-0.6	-0.4	-0.6
Reaction time num false alarms AUC	0.5	0.7	1.3	-0.3	-1.1	1.2	-1.2	-0.6	-0.7	-0.8	-0.8	-0.7	-0.9
Reaction time trials correct on left	1.1	2.2	5.0	-2.2	-1.8	1.7	-2.2	-0.4	-0.8	-1.5	-0.6	-1.2	-1.1
Reaction time trials on left	1.2	2.2	4.9	-2.2	-1.8	1.7	-2.2	-0.4	-0.8	-1.4	-0.7	-1.2	-1.1
Reaction time mean	2.4	3.8	7.7	2.5	2.3	-2.2	2.7	0.5	1.3	2.8	1.0	1.6	1.2
Reaction time mean AUC	2.5	4.0	7.6	2.8	2.5	-2.4	2.6	1.0	1.7	2.5	0.5	1.3	1.1
Median of all reaction times	2.9	4.1	7.6	2.8	2.5	-2.3	2.7	0.6	1.4	2.7	0.9	1.7	1.3
Reaction time omissions	0.2	0.3	0.5	-0.1	-0.6	0.6	-0.6	-0.7	-0.5	-0.2	-0.3	-0.6	-0.6
Reaction time false alarm rate	0.1	0.2	0.8	0.9	-0.1	0.2	-0.0	-0.5	-0.3	-0.0	-0.5	-0.2	-0.4
Reaction time premature initiation rate	0.1	0.1	0.4	0.4	0.1	-0.0	-0.1	-0.3	-0.0	-0.2	-0.7	-0.5	-0.5
Reaction time premature initiations	0.4	0.7	1.3	-0.6	-0.7	0.7	-1.1	-0.2	-0.3	-1.0	-1.0	-1.0	-0.9
Std. dev. reaction times	0.9	1.6	3.7	1.7	1.5	-1.4	1.8	0.2	0.9	1.9	0.6	0.6	0.6
Reaction time trials completed	1.2	2.2	4.9	-2.2	-1.8	1.7	-2.2	-0.4	-0.8	-1.4	-0.7	-1.2	-1.1
Reaction time trials AUC	1.1	2.0	4.5	-2.1	-1.7	1.6	-2.1	-0.3	-0.7	-1.4	-0.7	-1.2	-1.1
Run reversals in cocaine runway, females	0.7	0.7	2.1	1.5	1.3	-1.2	0.4	-0.0	0.8	-0.1	-0.5	0.1	-0.7
Run reversals in cocaine runway, males	0.9	0.9	1.5	0.4	0.9	-0.9	1.2	0.9	0.8	0.9	0.8	1.2	1.1
Latency to leave start box in cocaine runway	0.7	0.8	4.1	2.0	0.6	-0.5	1.2	-1.1	-0.6	-0.0	0.0	0.0	0.1
Latency to leave start box in cocaine runway, F	0.6	0.6	3.6	1.9	0.4	-0.3	0.6	-0.8	-0.5	-0.7	-0.6	-0.6	-0.3
Latency to leave start box in cocaine runway, M	1.4	1.3	2.5	1.3	0.8	-0.7	1.6	-0.4	-0.2	1.3	1.3	1.5	1.2
Std. dev. time between licks in bursts	1.1	1.5	2.4	-0.8	-1.6	1.5	-1.6	-1.3	-1.4	-1.4	-0.2	-0.7	-0.8
Total sessions with >9 infusions	1.3	1.5	3.6	1.2	0.1	-0.1	1.5	-0.1	-0.4	1.9	1.7	1.3	1.9
Short access day 1 total inactive lever presses	2.8	3.6	8.8	2.7	2.0	-1.9	3.0	0.7	1.0	2.3	1.3	1.3	1.5
Short access day 10 total inactive lever presses	0.1	0.1	0.5	0.7	0.2	-0.1	0.3	-0.7	-0.2	0.5	0.1	-0.1	-0.2
Short access day 1 total infusions	0.3	0.5	0.8	0.5	0.6	-0.7	0.9	0.7	0.5	0.6	0.7	0.6	0.9
Short access day 10 total infusions	0.3	0.4	1.6	1.3	0.5	-0.4	0.6	0.7	0.5	0.7	0.2	0.1	0.5
Short access total infusions	0.2	0.2	0.7	0.6	0.4	-0.3	0.3	0.8	0.5	0.3	0.2	0.2	0.5
Short access day 1 locomotion	3.6	4.5	9.7	2.2	2.1	-2.1	3.1	1.5	1.4	2.6	1.6	1.9	2.1
Short access day 10 total locomotion	0.6	1.2	4.7	0.6	-1.2	1.3	-0.3	-2.2	-1.8	0.5	0.6	0.1	0.2
Short access total locomotion	1.1	1.3	3.5	-0.2	-1.8	1.9	-0.8	-1.5	-1.8	0.1	0.5	-0.3	0.3
One hour access (0.3 mA shock)	3.6	4.1	16.1	4.0	1.6	-1.3	2.4	-1.2	-0.1	2.8	1.3	1.4	1.4
Compulsive drug intake	1.6	1.9	4.1	2.0	0.8	-0.7	2.0	-0.7	-0.4	1.8	1.3	1.4	1.5
One hour access (shock baseline)	2.0	3.1	10.5	3.2	2.3	-2.1	1.9	0.7	1.5	1.8	0.1	0.8	0.4
Social response proportion	3.2	3.7	12.9	3.6	2.4	-2.3	2.7	0.3	0.9	1.7	0.4	0.9	1.0
Social responses	2.4	3.2	6.1	2.1	1.7	-1.6	2.5	-0.7	0.0	2.3	1.9	1.9	1.5
Social time	3.3	4.6	14.6	-1.6	-2.5	2.6	-1.4	-3.8	-3.3	-0.1	1.7	0.0	-0.0
Soleus weight	0.2	0.5	1.2	-0.1	-1.0	1.0	-1.1	-0.1	-0.8	-1.0	-0.4	-0.2	-0.1
Bone: stiffness	0.8	1.3	3.4	-0.1	-0.5	0.5	0.6	-1.8	-1.5	1.1	1.8	1.1	1.0
Tibialis anterior weight	0.8	2.6	6.6	-0.8	-1.1	1.1	-2.1	1.5	0.3	-2.6	-2.3	-1.9	-1.1
Time to tail flick, vehicle, before self-admin	0.9	1.0	2.4	0.1	-1.3	1.4	-0.5	-1.4	-1.5	-0.5	-0.2	-0.9	-0.4
Time to tail flick, vehicle, after self-admin	1.9	2.5	5.0	1.3	2.1	-2.1	2.2	0.5	1.2	1.7	0.7	1.8	0.8
Time to tail flick, test, before self-admin	7.1	7.4	15.0	-2.9	-3.9	3.8	-3.1	-2.6	-3.1	-2.2	-0.4	-2.0	-1.0
Time to tail flick, test, after self-admin	0.1	0.1	0.2	-0.1	0.3	-0.3	0.3	0.4	0.5	-0.0	-0.4	-0.2	-0.3
Delta time to tail flick, vehicle, before/after SA	2.6	2.4	5.1	0.6	2.2	-2.3	1.9	1.4	1.8	1.3	0.7	1.7	0.9
Delta time to tail flick, test, before/after SA	4.0	4.1	8.0	2.1	2.8	-2.8	2.6	1.8	2.3	1.8	0.3	1.4	0.6
Tibia length	1.5	4.1	11.7	-1.9	-1.5	1.4	0.0	-3.4	-2.5	1.4	3.1	1.6	1.0
Ambulatory time before self-admin	3.6	5.4	12.8	-1.8	-3.6	3.6	-1.6	-2.8	-3.5	-0.4	1.0	-0.8	0.5
Ambulatory time after self-admin	7.6	8.9	18.3	-2.8	-4.3	4.3	-3.4	-3.0	-3.5	-2.3	-0.6	-2.3	-1.2
Bone: tissue strength	4.3	4.3	7.3	-1.0	-2.7	2.7	-2.7	-2.2	-2.6	-2.1	-0.8	-1.5	-1.4
Total heroin consumption	0.2	0.2	0.8	0.1	-0.5	0.5	-0.3	-0.2	-0.4	-0.6	-0.3	-0.9	-0.3
Bone: trabecular number	0.6	1.0	4.9	-2.2	-1.4	1.3	-0.9	0.7	-0.3	-0.3	0.4	0.2	0.2
Bone: trabecular spacing	0.1	0.1	0.2	-0.1	-0.1	0.1	-0.3	-0.5	-0.2	-0.5	-0.2	-0.4	-0.2
Bone: trabecular thickness	0.2	0.3	0.8	0.3	0.4	-0.5	0.8	0.9	0.5	0.3	0.3	0.4	0.4
Bone: trabecular tissue density	2.8	4.2	8.8	3.0	2.8	-2.8	2.2	2.1	2.4	0.7	-1.4	-0.0	0.0
Water consumed over 24 hours	1.0	1.4	3.6	-0.9	-1.4	1.4	-1.2	-1.8	-1.9	-0.6	0.7	0.2	-0.1
Number of responses in last shaping day	3.9	4.3	9.3	3.0	2.7	-2.6	2.6	1.6	1.9	1.7	0.5	1.5	0.9