Zfp110

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Zfp110 0.45 0.16 3.1e-04 -0 0.06 0.06 0.01 7.6e-01 4.0e-04 2.8e-04 1.2e-01
2 NAcc alternative TSS NM_001024775.1 0.13 0.09 1.2e-03 -0 0.02 0.02 -0 4.8e-01 3.9e-04 1.1e-03 5.6e-01
3 NAcc alternative TSS XM_006228111.5 0.16 0.1 1.7e-04 -0 0.02 0.02 0 5.6e-01 4.6e-04 1.4e-03 2.2e-01
4 NAcc gene expression Zfp110 0.42 0.12 0.0e+00 0.1 0.18 0.18 0.16 2.5e-14 5.6e-26 4.3e-26 3.6e-24
5 Adipose gene expression Zfp110 0.13 0.07 1.2e-04 0 0.02 0.02 0 3.3e-01 1.5e-03 1.2e-03 1.7e-01
6 pVTA gene expression Zfp110 0.28 0.12 4.2e-08 0.01 0.1 0.07 0.04 4.9e-02 3.4e-08 1.6e-06 2.2e-04
7 PL gene expression Zfp110 0.42 0.13 5.4e-13 0.01 0.12 0.12 0.1 1.4e-02 1.1e-12 2.1e-13 1.5e-10
8 Brain gene expression Zfp110 0.39 0.15 3.3e-04 0.02 0.03 0.03 0.03 2.5e-03 5.5e-04 2.0e-03 3.9e-04
9 IC gene expression Zfp110 0.57 0.13 1.3e-11 0.06 0.25 0.26 0.26 1.3e-03 5.0e-11 3.2e-11 3.3e-11
10 Liver gene expression Zfp110 0.19 0.1 4.6e-07 0.03 0.04 0.04 0.02 5.6e-04 5.5e-05 3.8e-05 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.30.52.11.5-0.90.80.3-0.1-0.4-0.20.8-0.5-0.7
Area under the delay curve0.61.01.70.7-0.80.81.20.5-0.51.3-1.31.31.1
BMI with tail0.31.03.0-0.60.2-0.20.1-1.71.01.1-1.70.81.0
BMI without tail0.10.42.6-1.60.2-0.00.00.0-0.10.7-0.90.50.4
Body weight0.20.92.8-1.20.10.0-0.91.7-1.0-0.81.2-0.5-0.5
Weight adjusted by age0.41.12.90.5-1.51.50.81.3-1.70.40.70.10.2
Bone surface1.52.910.01.1-0.60.5-0.81.2-1.2-1.83.2-2.1-2.5
Bone volume1.32.68.80.9-0.40.3-1.10.9-0.9-1.83.0-2.1-2.4
Breakpoint value in progressive ratio session0.71.24.0-1.10.7-0.60.80.30.61.0-2.01.61.2
Number of licking bursts0.10.31.3-1.10.8-0.8-0.4-0.30.30.5-0.30.1-0.1
Context. condit. distance diff. score0.60.82.51.6-1.11.11.20.6-0.50.10.00.50.3
Locomotion velocity, session 11.41.64.21.4-1.51.51.42.0-1.50.40.70.70.5
Locomotion distance, session 12.83.613.41.6-2.01.91.33.7-2.7-0.11.80.20.2
Locomotion velocity, session 20.40.51.71.3-0.80.80.80.7-0.60.10.50.20.1
Locomotion distance, session 20.91.23.50.5-0.60.6-0.41.6-1.3-1.11.9-1.0-1.0
Locomotion velocity, session 30.20.20.50.40.2-0.2-0.2-0.40.4-0.70.5-0.5-0.6
Locomotion distance, session 31.82.18.72.9-1.81.71.10.6-0.9-0.61.6-0.6-0.9
Stereotopy head waving bouts, day 30.60.72.6-1.61.0-0.9-0.30.40.40.3-1.00.91.0
Stereotopy head waving duration, day 30.81.03.4-1.91.1-1.0-0.50.60.30.3-1.11.01.3
Locomotion velocity, session 70.10.20.70.2-0.10.2-0.10.8-0.4-0.60.5-0.1-0.1
Locomotion distance, session 70.10.20.30.3-0.60.60.30.5-0.6-0.30.30.0-0.1
Stereotopy head waving bouts, day 70.40.51.20.20.7-0.8-0.80.00.6-1.10.8-0.6-0.6
Stereotopy head waving duration, day 70.10.20.4-0.00.5-0.5-0.60.30.2-0.60.5-0.3-0.3
Locomotion velocity, session 80.40.51.20.7-0.90.90.81.1-0.80.20.00.40.3
Locomotion distance, session 80.81.23.11.8-1.41.41.11.2-1.1-0.30.9-0.0-0.1
Degree of sensitization distance0.60.72.9-1.70.5-0.4-0.20.7-0.20.5-1.00.80.9
Degree of sensitization stereotypy0.70.72.51.60.0-0.1-0.2-0.60.6-0.91.1-0.9-1.1
Conditioned locomotion0.60.71.20.5-0.91.01.11.1-0.90.5-0.30.90.8
Cocaine response after cond. corrected3.55.29.4-2.83.1-3.0-2.5-2.92.7-1.3-0.8-0.9-0.7
Cocaine response after cond. not corrected1.52.24.3-1.91.9-1.9-2.1-0.91.1-1.50.5-1.1-1.1
Cocaine response before conditioning4.25.114.82.1-2.52.51.23.8-3.2-0.12.5-0.4-0.7
Saline control response1.11.55.02.2-1.51.41.21.1-1.20.21.2-0.3-0.6
Bone: connectivity density0.40.73.71.9-0.80.70.6-0.90.1-0.00.6-0.3-0.6
Bone: cortical apparent density0.40.64.2-2.10.5-0.4-0.8-0.4-0.1-0.0-0.5-0.0-0.1
Bone: cortical area1.01.73.41.4-1.81.81.11.4-1.80.71.00.10.1
Bone: cortical porosity0.20.20.6-0.20.5-0.50.0-0.60.8-0.3-0.80.30.3
Bone: cortical porosity0.40.51.0-0.60.9-0.9-0.5-0.81.0-0.7-0.4-0.2-0.1
Bone: cortical thickness0.61.02.60.1-1.01.01.10.0-0.71.6-1.11.21.2
Bone: cortical thickness0.10.10.2-0.3-0.30.4-0.10.1-0.4-0.40.4-0.3-0.5
Bone: cortical tissue density0.40.74.5-2.10.7-0.6-0.9-0.50.1-0.1-0.4-0.1-0.2
Condit. Reinf. active minus inactive responses0.70.83.1-1.81.2-1.2-0.9-0.30.6-0.4-0.6-0.0-0.2
Condit. Reinf. active-inactive response ratio0.60.62.2-0.80.6-0.50.2-0.80.70.6-1.50.80.7
Condit. Reinf. active responses0.71.01.8-1.31.2-1.2-1.30.00.4-1.20.5-0.7-0.9
Condit. Reinf. inactive responses1.11.44.50.10.0-0.0-1.01.5-0.8-1.62.1-1.2-1.3
Incentive salience index mean0.30.31.5-1.20.5-0.5-0.70.6-0.2-0.50.0-0.2-0.3
Condit. Reinf. lever presses0.30.52.1-0.5-0.50.5-0.31.4-1.1-0.40.6-0.1-0.2
Condit. Reinf. active minus inactive responses1.42.15.51.3-1.21.10.22.3-1.8-0.72.3-1.0-1.0
Condit. Reinf. active-inactive response ratio1.11.85.80.8-0.40.4-0.81.9-1.1-1.42.4-1.4-1.2
Condit. Reinf. active responses2.33.27.81.9-2.02.01.22.8-2.5-0.02.2-0.5-0.7
Condit. Reinf. inactive responses1.21.73.91.2-1.71.72.01.1-1.51.3-0.10.80.4
Condit. Reinf. lever presses0.71.02.31.4-1.21.21.50.8-1.00.90.10.50.4
Condit. Reinf. lever reinforcers received2.73.88.42.2-2.12.01.22.9-2.6-0.32.6-0.8-1.1
Conditioned reinforcement - actives0.83.013.8-3.71.9-1.7-2.2-0.71.0-1.60.4-0.9-0.3
Conditioned reinforcement - inactives0.71.88.6-2.9-0.20.4-1.01.8-1.5-1.11.1-0.7-0.3
Conditioned locomotion1.11.78.2-2.91.4-1.3-1.8-0.50.8-0.90.1-0.5-0.0
Patch foraging indifference point 0 sec1.33.56.31.4-2.12.12.51.2-1.42.1-1.32.22.0
Patch foraging indifference point AUC0.30.72.2-0.21.0-1.1-0.7-1.51.40.0-0.6-0.20.1
Delay disc. indifference point, 0s delay4.34.911.03.0-3.33.22.31.8-2.61.2-0.00.91.0
Delay disc. indifference point, 16s delay1.92.66.8-1.32.6-2.6-1.4-1.62.3-0.2-1.2-0.1-0.4
Delay disc. indifference point, 2s delay0.91.01.80.4-0.80.91.30.9-0.71.0-1.01.41.3
Delay disc. indifference point, 24s delay0.81.33.1-1.41.8-1.7-1.0-1.11.5-0.1-0.80.10.3
Delay disc. indifference point, 4s delay0.10.10.20.0-0.30.3-0.10.2-0.4-0.00.3-0.4-0.4
Delay disc. indifference point, 8s delay1.22.13.60.8-1.41.41.71.0-0.91.6-1.51.91.7
Indifference point function ln k1.75.221.30.6-2.32.41.24.6-3.7-0.52.10.2-0.2
Indifference point function log k1.75.221.30.6-2.32.41.24.6-3.7-0.52.10.2-0.2
Patch foraging total patch changes 0 sec1.23.55.91.1-2.12.12.41.1-1.42.2-1.42.32.0
Patch foraging total patch changes 12 sec0.20.31.60.30.4-0.4-0.2-1.30.90.4-0.5-0.0-0.0
Patch foraging total patch changes 18 sec0.40.81.91.3-0.60.51.1-0.50.21.4-0.81.01.0
Patch foraging total patch changes 24 sec0.62.13.9-0.21.5-1.6-2.0-1.91.8-1.20.8-1.4-1.1
Patch foraging total patch changes 6 sec0.50.92.6-0.50.4-0.40.3-1.20.91.1-1.60.91.0
Patch foraging time to switch 0 sec3.915.030.8-3.95.1-5.0-4.1-5.55.1-1.8-1.5-1.8-1.3
Patch foraging water rate 0 sec1.35.08.62.6-2.92.82.52.9-2.71.10.71.21.1
Patch foraging water rate 12 sec2.49.523.62.3-3.73.83.54.9-4.21.60.61.81.5
Patch foraging water rate 18 sec1.94.210.51.1-2.42.42.53.2-2.61.2-0.01.61.5
Patch foraging water rate 24 sec1.42.05.11.5-1.61.61.52.3-1.80.41.00.60.5
Patch foraging water rate 6 sec2.43.510.80.7-0.90.9-0.23.3-2.3-1.63.2-1.4-1.6
Seeking ratio, delayed vs. immediate footshock5.98.515.73.4-3.93.84.02.5-2.92.4-0.51.91.8
Distance traveled before self-admin4.08.720.31.4-4.44.52.33.8-4.41.00.61.41.7
Distance traveled after self-admin6.411.321.03.8-4.64.54.12.5-3.32.9-0.92.72.5
Extensor digitorum longus weight0.00.20.40.2-0.40.40.10.3-0.6-0.10.6-0.3-0.6
Bone: elastic displacement1.21.63.70.3-0.70.71.60.5-0.31.9-1.51.71.6
Bone: elastic work1.82.44.21.1-2.02.12.01.8-1.81.5-0.21.10.8
Bone: endosteal estimation1.53.610.81.7-0.60.6-0.92.3-1.2-2.43.3-2.1-2.0
Bone: endosteal perimeter0.81.95.41.5-1.21.1-0.11.8-1.4-1.02.3-1.1-1.0
Epididymis fat weight0.62.85.0-1.82.2-2.2-2.0-2.12.0-1.00.0-1.1-0.7
Delta time in closed arm before/after self-admin0.30.21.91.4-0.50.40.2-0.1-0.10.30.1-0.20.1
Delta time in open arm before/after self-admin0.81.04.3-2.1-0.20.3-0.91.3-1.0-1.20.7-0.2-0.1
Diff in mean of infusions in LGA sessions1.42.43.6-0.0-1.71.81.91.9-1.71.4-0.91.61.5
Delay discount exponential model param0.60.81.5-0.40.7-0.8-1.0-0.50.5-1.21.2-1.2-1.1
Extinction: sum of active levers before priming0.20.31.91.4-0.50.40.1-0.2-0.2-0.00.3-0.3-0.2
Active lever presses in extinction session 64.74.78.0-2.22.8-2.8-2.7-2.42.4-1.80.5-1.5-1.3
Bone: final force1.11.73.90.7-1.21.2-0.01.9-1.9-0.52.0-0.9-1.1
Bone: final moment1.62.65.81.2-1.71.70.32.4-2.3-0.52.3-0.9-1.2
Food consumed during 24 hour testing period0.40.73.6-0.7-0.60.70.11.9-1.40.20.20.50.3
Glucose1.32.05.00.2-0.90.91.40.3-0.41.9-2.21.92.0
Heart weight0.40.74.2-2.10.5-0.3-0.71.1-0.7-0.1-0.10.0-0.1
Delay discount hyperbolic model param0.91.22.0-0.41.0-1.0-1.3-0.60.7-1.31.2-1.4-1.3
Intermittent access intake day 1-15 change0.31.58.3-2.91.1-1.0-1.60.40.0-1.00.5-0.7-0.6
Intermittent access intake escalation0.52.713.0-3.61.6-1.4-2.30.30.2-1.50.8-1.0-0.7
Intermittent access intake escalation 20.30.61.4-1.1-0.70.80.41.2-1.10.4-0.10.50.6
Intermitt. access day 1 inactive lever presses0.44.719.8-4.52.1-1.8-3.00.50.6-2.80.5-1.1-0.6
Intermitt. access day 15 inactive lever presses0.84.511.3-3.41.9-1.7-3.00.00.4-3.01.5-2.0-1.8
Intermitt. access escalation Index0.20.61.6-0.60.5-0.50.1-0.50.51.3-1.01.01.2
Intermittent access day 1 total infusions0.41.13.3-1.80.9-0.8-1.2-0.40.5-1.40.7-1.0-0.5
Intermittent access day 15 total infusions1.74.221.2-4.62.4-2.2-2.50.00.9-1.60.2-0.8-0.5
Intermittent access terminal intake (last 3 days)1.42.412.7-3.61.7-1.5-1.70.20.5-1.50.3-0.8-0.5
Intermittent access total infusions2.63.013.4-3.71.7-1.5-2.00.10.6-2.10.8-1.2-0.9
Intermittent access day 1 locomotion0.71.44.7-2.21.0-0.9-1.60.50.2-1.50.7-1.1-0.7
Intermittent access day 15 total locomotion0.52.07.1-2.7-0.81.1-0.22.4-1.8-0.3-0.00.71.1
Intermittent access total locomotion2.02.410.6-3.30.7-0.5-1.91.3-0.6-2.01.2-1.2-0.6
Intermittent access standard deviation0.21.13.2-1.80.10.10.70.5-0.10.9-1.41.61.5
Left kidney weight0.97.024.5-0.6-1.11.2-1.15.0-3.3-2.93.8-1.7-2.1
Right kidney weight0.85.916.5-1.5-0.10.2-1.74.1-2.6-2.83.7-2.0-2.3
Cocaine induced anxiety0.20.61.1-0.50.3-0.3-0.90.9-0.5-1.00.9-0.9-1.1
Post-drug Anxiety1.92.14.4-0.51.6-1.6-1.8-0.41.0-1.90.9-1.6-2.1
Baseline Anxiety0.30.53.01.70.2-0.30.6-0.70.80.4-0.70.2-0.2
Tail length0.63.013.1-0.8-0.60.8-0.23.6-2.4-1.22.4-0.8-1.2
Length with tail0.83.810.2-1.10.6-0.5-1.72.7-1.4-2.43.2-1.9-2.0
Length without tail1.26.112.9-2.12.7-2.7-3.6-0.21.0-3.02.6-2.7-2.4
Times rat made contact with spout0.20.20.60.8-0.50.40.7-0.3-0.00.6-0.40.40.1
Lifetime Intake2.02.59.8-3.11.6-1.4-1.9-0.20.6-1.80.8-1.2-0.9
Liver weight, left0.30.61.5-0.90.1-0.0-0.61.2-0.8-0.81.0-0.5-0.8
Liver weight, right0.40.71.20.1-0.91.01.10.7-0.80.9-0.50.90.9
Locomotor activity0.10.20.60.2-0.10.10.3-0.70.40.4-0.80.40.2
Locomotor testing distance0.20.51.2-0.40.8-0.9-0.8-1.10.9-0.5-0.1-0.6-0.7
Locomotor testing rearing0.10.31.41.2-0.30.30.10.3-0.2-0.40.8-0.4-0.3
Locomotion in novel chamber0.81.13.92.00.0-0.21.4-0.20.61.5-1.10.90.3
Locomotion in novel chamber post-restriction0.51.44.32.1-0.20.11.7-0.30.21.9-1.21.20.8
Fecal boli incidents, locomotor time 10.30.71.30.3-1.11.21.01.0-1.10.10.20.50.7
Change in fecal boli incidents, locomotor task1.21.33.21.1-0.10.11.3-0.50.61.7-1.81.41.3
Time >=10cm from walls, locomotor time 10.40.51.1-0.71.0-1.0-0.5-0.91.1-0.2-0.5-0.2-0.5
Bouts of movement, locomotor time 14.25.410.32.0-3.23.22.32.8-2.91.8-0.31.51.5
Total resting periods, locomotor time 12.63.04.32.1-2.12.01.92.0-1.81.5-0.71.41.1
Rest time, locomotor task time 10.30.51.11.0-0.1-0.0-0.30.5-0.5-0.50.9-1.0-1.1
Distance moved, locomotor task time 10.10.40.9-0.40.1-0.00.4-0.50.40.9-0.91.00.9
Vertical activity count, locomotor time 10.74.97.91.2-2.42.52.80.7-1.32.7-2.02.72.6
Time >=10cm from walls, locomotor time 20.41.33.2-0.01.5-1.6-0.8-1.71.8-0.2-0.3-0.6-0.8
Bouts of movement, locomotor time 20.20.63.71.9-0.50.41.00.2-0.10.6-0.30.0-0.5
Total resting periods, locomotor time 20.20.95.82.4-0.80.61.20.3-0.30.8-0.30.0-0.6
Rest time, locomotor task time 21.52.58.83.0-1.91.81.81.1-1.31.3-0.20.70.4
Distance moved, locomotor task time 20.10.10.6-0.80.1-0.1-0.2-0.50.1-0.10.2-0.10.0
Vertical activity count, locomotor time 20.40.92.20.1-1.41.51.30.2-0.91.0-0.20.80.8
Light reinforcement 10.52.34.32.0-2.12.02.01.4-1.61.20.11.00.6
Light reinforcement 20.20.51.2-0.50.5-0.50.2-1.10.80.8-1.00.50.5
Bone: marrow area1.53.710.91.7-0.60.6-0.92.3-1.2-2.43.3-2.1-2.1
Bone: maximum diameter0.51.12.31.1-1.51.50.51.2-1.50.21.1-0.2-0.1
Bone: maximum force1.12.25.11.1-1.71.60.42.2-2.3-0.32.0-0.7-1.0
Bone: maximum moment1.73.27.01.6-2.12.10.82.6-2.6-0.22.2-0.7-1.1
Mean time between licks in bursts0.21.12.30.1-0.90.91.2-0.0-0.41.4-1.31.51.2
Mean num. licks in bursts0.20.52.21.5-1.00.90.70.1-0.4-0.30.2-0.0-0.1
Cd content in liver0.50.61.9-0.10.1-0.1-0.81.1-0.7-0.91.4-0.7-0.5
Co content in liver0.40.41.1-1.00.2-0.2-0.50.9-0.7-0.60.7-0.6-0.5
Cu content in liver2.12.55.1-1.01.5-1.5-2.30.10.5-2.21.9-1.7-1.8
Fe content in liver1.41.73.4-1.91.6-1.5-1.8-0.70.8-1.40.7-1.1-1.1
K content in liver0.10.10.30.30.3-0.3-0.40.10.2-0.50.5-0.10.0
Mg content in liver0.80.91.9-0.61.4-1.4-1.1-1.01.2-0.90.1-0.4-0.4
Mn content in liver0.50.61.3-0.71.1-1.1-0.9-0.71.1-0.6-0.1-0.3-0.3
Na content in liver0.60.72.30.21.0-1.0-0.2-1.21.5-0.1-0.80.40.3
Rb content in liver2.02.36.2-0.01.1-1.2-1.71.40.1-2.52.3-1.5-1.5
Se content in liver1.01.23.3-0.40.7-0.70.3-1.51.40.8-1.81.11.0
Sr content in liver6.85.911.01.7-2.22.23.2-0.2-0.63.3-3.02.92.8
Zn content in liver2.93.46.2-2.12.5-2.5-2.2-2.22.2-1.2-0.3-0.8-0.6
Bone: minimum diameter2.24.17.92.7-2.32.21.02.7-2.5-0.52.8-0.9-0.9
Time in familiar zone, hab. session 14.65.011.52.3-3.03.01.73.4-3.10.31.70.20.0
Time in novel zone, hab. session 14.24.710.2-2.23.0-3.0-1.9-3.22.9-0.6-1.0-0.8-0.6
Total zone transitions, hab. session 11.92.75.52.3-1.71.70.92.2-1.8-1.12.1-0.6-0.8
Total locomotion distance, hab. session 12.23.15.92.3-2.42.42.21.9-2.00.70.60.70.7
Locomotion velocity, hab. session 11.42.03.61.8-1.91.91.71.6-1.60.50.50.60.6
Time in familiar zone, hab. session 21.11.32.9-0.90.7-0.7-1.20.2-0.1-1.51.7-1.4-1.7
Time in novel zone, hab. session 20.30.41.00.00.5-0.5-0.1-1.00.90.4-1.00.20.6
Total zone transitions, hab. session 23.64.711.02.9-2.62.61.73.3-2.7-0.11.90.20.2
Total locomotion distance, hab. session 23.24.27.62.4-2.72.72.81.7-2.01.7-0.21.51.5
Locomotion velocity, hab. session 23.85.08.92.6-2.92.93.01.9-2.11.9-0.41.71.8
Novel to familiar place preference ratio0.81.11.81.2-1.11.11.31.2-0.91.2-0.30.90.9
Novelty place preference0.60.71.91.0-0.90.91.01.4-0.90.80.10.50.6
Time in novel zone, NPP test0.40.51.50.8-0.70.70.81.2-0.80.60.10.30.4
Total zone transitions, NPP test0.81.22.41.2-1.51.51.11.4-1.40.40.30.50.5
Total locomotion distance, NPP test1.72.44.41.4-1.91.92.11.3-1.51.6-0.51.31.5
Locomotion velocity, NPP test2.23.15.51.7-2.22.22.31.6-1.81.6-0.31.41.5
Intraocular pressure0.20.41.1-0.20.5-0.5-0.5-0.50.4-0.70.6-0.8-1.0
Delta distance traveled before/after self-admin1.31.52.81.1-0.30.31.7-0.50.61.7-1.61.71.3
Delta ambulatory time before/after self-admin0.91.63.30.8-0.50.51.7-0.10.21.8-1.71.81.5
Parametrial fat weight1.22.98.7-0.3-0.40.51.0-1.30.62.1-2.92.42.5
Pavlov. Cond. lever latency0.00.00.1-0.00.3-0.3-0.0-0.30.30.10.1-0.2-0.1
Pavlov. Cond. magazine entry latency0.40.51.60.2-0.0-0.00.5-1.30.60.8-1.00.60.6
Pavlov. Cond. change in total contacts0.10.10.20.3-0.40.40.40.0-0.10.3-0.50.50.5
Pavlov. Cond. index score0.20.20.50.3-0.30.30.5-0.30.00.5-0.70.60.6
Pavlov. Cond. latency score0.20.30.60.2-0.40.40.6-0.2-0.10.6-0.80.70.6
Pavlov. Cond. lever contacts0.00.00.1-0.10.1-0.1-0.2-0.00.0-0.3-0.0-0.0-0.1
Pavlov. Cond. magazine entry number0.20.20.7-0.80.4-0.4-0.60.8-0.2-0.40.4-0.3-0.2
Pavlov. Cond. intertrial magazine entries0.70.82.20.9-1.11.11.01.5-1.10.50.40.30.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.60.2-0.30.30.5-0.30.10.5-0.80.60.6
Pavlov. Cond. response bias0.10.10.70.30.2-0.2-0.1-0.90.5-0.3-0.1-0.2-0.3
Pavlov. Cond. lever latency2.94.09.6-2.32.2-2.1-3.1-0.51.1-2.41.3-2.0-1.8
Pavlov. Cond. magazine entry latency1.01.43.00.8-0.50.51.6-0.70.21.7-1.71.51.4
Pavlov. Cond. change in total contacts1.33.26.22.5-2.42.32.41.4-1.71.50.11.10.8
Pavlov. Cond. index score1.42.15.01.8-1.61.52.20.3-0.81.8-0.91.51.2
Pavlov. Cond. latency score1.52.45.41.5-1.41.42.3-0.1-0.52.1-1.51.81.5
Pavlov. Cond. lever contacts2.53.68.42.3-2.12.12.90.7-1.22.2-1.01.81.6
Pavlov. Cond. magazine entry number0.60.81.5-0.90.6-0.5-1.20.8-0.1-1.21.1-1.0-0.8
Pavlov. Cond. intertrial magazine entries1.22.58.80.2-0.10.1-1.32.0-1.2-1.73.0-1.9-1.7
Pavlov. Cond. lever-magazine prob. diff.1.32.04.71.7-1.51.42.20.2-0.71.8-0.91.51.2
Pavlov. Cond. response bias2.02.75.92.4-2.12.02.41.0-1.41.6-0.11.20.8
Time in closed arm before self-admin0.50.96.6-2.60.2-0.0-0.31.1-0.6-0.50.10.30.4
Time in closed arm after self-admin0.10.20.5-0.40.7-0.7-0.10.10.4-0.40.0-0.2-0.4
Time in open arm before self-admin1.41.710.03.2-0.90.71.4-1.00.31.6-0.60.40.3
Time in open arm after self-admin0.20.21.51.2-0.60.60.3-0.2-0.20.3-0.00.10.1
Bone: periosteal estimation1.33.07.62.2-1.71.60.22.1-1.9-1.02.8-1.3-1.3
Bone: periosteal perimeter1.22.47.62.1-1.41.30.01.2-1.4-0.82.8-1.5-1.6
Bone: post-yield work1.52.66.40.10.7-0.7-1.80.5-0.2-2.32.5-2.2-2.2
Progressive ratio test 1 active lever presses0.40.71.8-0.5-1.11.2-0.11.0-1.3-0.61.0-0.5-0.2
Progressive ratio test 1 breakpoint0.40.71.8-0.4-1.21.2-0.11.0-1.3-0.60.9-0.5-0.2
Progressive ratio test 1 inactive lever presses1.12.97.7-2.80.6-0.4-2.20.8-0.6-2.71.7-1.8-1.3
Progressive ratio test 2 active lever presses2.23.114.3-3.81.9-1.7-2.3-0.50.9-1.70.4-0.9-0.4
Progressive ratio test 2 breakpoint2.83.515.2-3.92.1-1.8-2.4-0.51.0-1.90.6-1.1-0.6
Progressive ratio test 2 inactive lever presses1.13.612.6-3.50.7-0.5-2.41.2-0.8-2.71.8-1.6-1.2
Incentive Sensitization - Responses2.05.422.0-4.72.7-2.5-3.1-0.41.1-2.10.7-1.4-0.8
Incentive Sensitization - Breakpoint2.35.320.8-4.62.8-2.6-3.0-0.61.3-2.00.6-1.2-0.7
Sum of active levers in priming session hrs 5-61.31.32.2-0.1-0.91.01.11.4-1.01.2-1.01.51.4
Progressive ratio0.61.74.11.7-2.02.01.60.7-1.20.8-0.10.60.5
Food seeking constrained by brief footshock28.535.671.45.6-8.48.46.95.5-6.84.9-0.94.14.0
Seeking ratio, punishment vs. effort1.32.96.01.0-2.22.21.52.5-2.41.20.21.01.1
Retroperitoneal fat weight2.511.130.8-2.62.8-2.7-0.7-5.54.32.2-4.82.02.7
Reaction time number correct0.62.35.12.3-1.81.72.20.4-0.81.5-0.61.41.2
Reaction time mean minus median0.10.61.3-0.60.9-0.9-1.1-0.60.8-1.10.4-0.7-0.4
Reaction time mean minus median AUC0.21.12.1-0.21.2-1.2-1.5-1.21.2-1.20.8-1.0-0.7
Reaction time num false alarms0.10.20.4-0.5-0.40.50.50.5-0.40.2-0.60.60.4
Reaction time num false alarms AUC0.30.81.30.3-1.11.21.20.6-0.70.8-0.81.00.8
Reaction time trials correct on left0.62.35.12.3-1.81.72.20.4-0.81.5-0.61.41.2
Reaction time trials on left0.72.35.02.2-1.81.72.20.4-0.81.4-0.71.41.2
Reaction time mean1.84.07.8-2.52.3-2.2-2.7-0.51.3-2.81.0-1.8-1.5
Reaction time mean AUC1.74.17.7-2.82.5-2.4-2.6-1.01.7-2.60.5-1.6-1.3
Median of all reaction times2.84.37.8-2.82.5-2.3-2.7-0.61.4-2.80.8-1.9-1.6
Reaction time omissions0.20.30.50.1-0.60.60.60.7-0.50.2-0.40.50.6
Reaction time false alarm rate0.10.20.8-0.9-0.10.20.00.5-0.30.0-0.50.30.2
Reaction time premature initiation rate0.10.10.5-0.40.1-0.00.10.3-0.00.2-0.70.40.5
Reaction time premature initiations0.20.71.30.6-0.70.71.10.2-0.31.0-1.01.01.1
Std. dev. reaction times0.51.63.7-1.71.5-1.4-1.8-0.20.9-1.90.6-1.0-0.5
Reaction time trials completed0.72.35.02.2-1.81.72.20.4-0.81.4-0.71.41.2
Reaction time trials AUC0.62.14.62.1-1.71.62.10.3-0.71.4-0.71.41.2
Run reversals in cocaine runway, females0.60.62.1-1.51.3-1.2-0.40.00.80.1-0.60.1-0.1
Run reversals in cocaine runway, males0.80.91.5-0.40.9-0.9-1.2-0.90.8-0.90.8-1.2-1.2
Latency to leave start box in cocaine runway0.60.84.2-2.10.6-0.5-1.21.1-0.60.0-0.0-0.2-0.0
Latency to leave start box in cocaine runway, F0.50.63.5-1.90.4-0.3-0.60.8-0.50.7-0.50.40.6
Latency to leave start box in cocaine runway, M1.41.32.5-1.40.8-0.7-1.60.4-0.2-1.31.3-1.5-1.4
Std. dev. time between licks in bursts0.81.62.40.8-1.61.51.61.3-1.41.5-0.31.30.7
Total sessions with >9 infusions1.21.53.5-1.30.1-0.1-1.50.1-0.4-1.91.7-1.7-1.2
Short access day 1 total inactive lever presses1.93.88.8-2.82.0-1.9-3.0-0.71.0-2.31.3-1.7-1.3
Short access day 10 total inactive lever presses0.00.10.5-0.70.2-0.1-0.30.7-0.2-0.50.1-0.10.1
Short access day 1 total infusions0.20.50.9-0.50.6-0.7-0.9-0.70.5-0.60.7-0.9-0.6
Short access day 10 total infusions0.20.41.6-1.20.5-0.4-0.6-0.70.5-0.70.3-0.4-0.1
Short access total infusions0.10.20.7-0.60.4-0.3-0.3-0.80.5-0.30.3-0.5-0.2
Short access day 1 locomotion2.84.79.7-2.22.1-2.1-3.1-1.51.4-2.61.7-2.5-1.9
Short access day 10 total locomotion0.31.24.7-0.7-1.21.30.32.2-1.8-0.40.5-0.1-0.1
Short access total locomotion0.91.33.50.1-1.81.90.81.5-1.8-0.00.50.10.3
One hour access (0.3 mA shock)3.64.317.0-4.11.6-1.3-2.41.2-0.1-2.81.2-1.7-1.4
Compulsive drug intake1.31.94.3-2.10.8-0.7-2.00.7-0.4-1.81.3-1.4-1.4
One hour access (shock baseline)1.23.110.5-3.22.3-2.1-1.9-0.71.5-1.90.2-1.0-0.7
Social response proportion2.93.713.1-3.62.4-2.3-2.7-0.30.9-1.70.4-1.1-0.9
Social responses2.53.36.1-2.21.7-1.6-2.50.70.0-2.32.0-1.8-1.9
Social time2.94.514.61.5-2.52.61.43.8-3.30.21.80.40.0
Soleus weight0.20.51.20.1-1.01.01.10.1-0.81.0-0.30.50.2
Bone: stiffness0.71.33.60.0-0.50.5-0.61.8-1.5-1.11.9-1.0-1.1
Tibialis anterior weight0.82.86.60.9-1.11.12.1-1.50.32.6-2.31.81.8
Time to tail flick, vehicle, before self-admin0.81.02.4-0.1-1.31.40.51.4-1.50.5-0.20.80.9
Time to tail flick, vehicle, after self-admin1.32.75.0-1.32.1-2.1-2.2-0.51.2-1.70.7-1.6-1.8
Time to tail flick, test, before self-admin6.77.615.02.9-3.93.83.12.6-3.12.2-0.51.92.0
Time to tail flick, test, after self-admin0.10.10.20.10.3-0.3-0.3-0.40.50.0-0.40.00.2
Delta time to tail flick, vehicle, before/after SA2.52.65.1-0.72.2-2.3-1.9-1.41.8-1.30.6-1.6-1.7
Delta time to tail flick, test, before/after SA3.54.38.0-2.12.8-2.8-2.6-1.82.3-1.80.3-1.5-1.4
Tibia length1.54.111.71.7-1.51.4-0.03.4-2.5-1.33.2-1.1-1.5
Ambulatory time before self-admin1.85.412.81.7-3.63.61.62.8-3.50.41.00.60.8
Ambulatory time after self-admin5.89.318.32.7-4.34.33.43.0-3.52.3-0.62.32.3
Bone: tissue strength4.34.57.31.0-2.72.72.72.2-2.62.1-0.81.91.5
Total heroin consumption0.20.20.8-0.1-0.50.50.30.2-0.40.6-0.30.50.9
Bone: trabecular number0.51.05.02.2-1.41.30.9-0.7-0.30.30.4-0.2-0.3
Bone: trabecular spacing0.10.10.30.1-0.10.10.30.5-0.20.5-0.20.40.4
Bone: trabecular thickness0.20.30.8-0.30.4-0.5-0.8-0.90.5-0.30.3-0.6-0.4
Bone: trabecular tissue density2.44.18.2-2.92.8-2.8-2.2-2.12.4-0.7-1.4-0.20.1
Water consumed over 24 hours0.71.43.60.8-1.41.41.21.8-1.90.60.70.3-0.2
Number of responses in last shaping day3.44.49.2-3.02.7-2.6-2.6-1.61.9-1.70.5-1.4-1.4