Hub : Genes

Zfp110

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Zfp110 0.4 0.14 7.9e-14 0.06 0.11 0.1 0.09 5.0e-08 4.8e-13 4.3e-12 1.6e-10
2 BLA gene expression Zfp110 0.46 0.17 3.8e-04 0.01 0.06 0.07 0.02 7.1e-02 2.8e-04 1.4e-04 4.0e-02
3 Adipose gene expression Zfp110 0.13 0.08 2.3e-04 -0 0.02 0.02 0 6.8e-01 5.8e-03 3.0e-03 1.6e-01
4 PL gene expression Zfp110 0.45 0.14 2.0e-12 -0 0.11 0.11 0.09 6.2e-01 1.1e-11 9.2e-12 1.9e-10
5 Liver gene expression Zfp110 0.24 0.13 4.2e-07 0.03 0.04 0.05 0.03 5.7e-04 3.0e-05 7.2e-06 2.7e-04
6 Adipose isoform ratio NM_001024775.1 0.07 0.06 6.4e-03 0.01 -0 0 0 4.0e-02 4.0e-01 2.1e-01 1.3e-01
7 RMTg isoform ratio XM_006228111.4 0.11 0.09 7.2e-03 0.05 0.06 0.04 0.05 1.7e-02 1.3e-02 3.5e-02 2.3e-02
8 Brain gene expression Zfp110 0.33 0.16 5.2e-03 0 -0 -0 -0 2.2e-01 5.1e-01 4.5e-01 9.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.30.8-0.60.9-0.10.3-0.80.10.5-0.4
Area under the delay curve2.02.14.4-1.70.61.51.62.1-1.2-0.91.6
BMI with tail0.62.03.9-1.31.0-0.21.00.9-2.0-1.92.0
BMI without tail2.24.69.9-1.8-0.73.02.53.2-1.1-1.02.3
Body weight0.20.84.20.9-2.10.5-0.00.40.60.20.2
Weight adjusted by age0.70.81.9-0.3-0.41.40.80.31.01.3-0.7
Bone surface1.83.26.11.3-1.2-0.1-0.8-2.12.42.5-2.4
Bone volume1.62.85.01.3-1.0-0.3-1.0-2.22.12.1-2.1
Breakpoint value in progressive ratio session3.94.211.8-1.1-1.02.12.03.4-1.6-1.82.4
Number of licking bursts0.20.31.10.7-1.10.2-0.00.70.3-0.00.3
Context. condit. distance diff. score0.40.41.5-1.11.20.30.7-0.0-0.5-0.00.0
Locomotion velocity, session 10.40.41.0-0.5-0.11.00.60.40.50.9-0.8
Locomotion distance, session 11.92.45.20.2-1.22.10.90.71.92.3-1.8
Locomotion velocity, session 20.10.10.3-0.20.10.00.1-0.20.20.5-0.5
Locomotion distance, session 21.31.83.51.2-1.50.5-0.6-0.41.91.9-1.7
Locomotion velocity, session 30.30.41.40.40.1-1.2-0.5-0.80.10.1-0.5
Locomotion distance, session 31.01.12.7-0.81.6-0.70.2-1.60.31.0-1.2
Stereotopy head waving bouts, day 30.70.83.30.5-1.30.50.31.8-0.2-0.70.5
Stereotopy head waving duration, day 30.91.03.20.8-1.80.80.21.80.0-0.60.6
Locomotion velocity, session 70.20.20.40.5-0.50.2-0.0-0.50.70.6-0.6
Locomotion distance, session 70.10.10.2-0.2-0.10.50.50.20.20.3-0.2
Stereotopy head waving bouts, day 70.70.81.90.9-0.2-1.1-1.1-1.40.50.4-0.9
Stereotopy head waving duration, day 70.40.40.70.8-0.6-0.7-0.8-0.90.50.4-0.6
Locomotion velocity, session 80.20.20.6-0.3-0.00.70.80.70.30.5-0.1
Locomotion distance, session 80.20.30.8-0.40.40.30.4-0.40.40.9-0.8
Degree of sensitization distance0.90.92.50.3-1.41.30.51.60.1-0.40.7
Degree of sensitization stereotypy1.11.23.70.11.3-1.6-1.0-1.90.00.3-0.8
Conditioned locomotion0.70.93.0-0.7-0.11.21.41.7-0.00.20.2
Cocaine response after cond. corrected2.52.86.81.8-1.1-2.6-2.5-1.6-0.6-1.40.6
Cocaine response after cond. not corrected1.82.04.51.9-1.5-1.5-2.1-1.70.70.1-0.6
Cocaine response before conditioning2.63.28.8-0.1-0.62.20.9-0.42.43.0-2.2
Saline control response0.50.71.8-0.80.80.51.3-0.20.51.1-0.7
Bone: connectivity density0.40.62.7-0.91.7-0.50.4-0.7-0.40.2-0.3
Bone: cortical apparent density0.60.72.41.2-1.5-0.2-1.20.20.2-0.60.4
Bone: cortical area0.50.71.4-0.3-0.91.21.10.20.81.1-0.5
Bone: cortical porosity0.60.62.30.10.1-1.5-0.4-0.5-0.9-1.00.5
Bone: cortical porosity0.50.62.40.4-0.1-1.5-0.6-0.8-0.6-0.80.2
Bone: cortical thickness0.71.22.3-1.1-0.00.91.51.5-0.9-0.81.2
Bone: cortical thickness0.20.20.50.1-0.70.5-0.2-0.40.50.5-0.2
Bone: cortical tissue density0.60.82.41.3-1.6-0.3-1.30.10.2-0.50.3
Condit. Reinf. active minus inactive responses0.30.31.10.8-1.0-0.3-0.20.40.0-0.40.3
Condit. Reinf. active-inactive response ratio0.60.71.6-0.50.3-0.30.50.6-1.1-1.21.3
Condit. Reinf. active responses0.60.71.91.4-1.2-0.6-0.9-0.50.80.3-0.6
Condit. Reinf. inactive responses1.92.24.11.5-1.30.1-1.1-1.31.91.8-2.0
Incentive salience index mean0.30.41.60.7-1.20.4-0.10.60.60.3-0.2
Condit. Reinf. lever presses0.50.72.00.3-1.11.40.20.81.00.9-0.4
Condit. Reinf. active minus inactive responses2.02.56.50.9-1.10.7-0.2-1.22.32.5-2.1
Condit. Reinf. active-inactive response ratio2.62.75.21.5-1.20.1-1.2-1.42.32.2-2.1
Condit. Reinf. active responses1.72.36.90.1-0.81.40.7-0.82.12.6-1.9
Condit. Reinf. inactive responses0.81.03.0-1.30.41.51.70.70.20.60.1
Condit. Reinf. lever presses0.20.31.2-0.80.40.31.10.10.00.5-0.1
Condit. Reinf. lever reinforcers received1.92.78.20.2-0.71.20.6-1.12.32.9-2.2
Conditioned reinforcement - actives2.02.06.42.2-2.5-0.7-1.9-0.10.5-0.4-0.1
Conditioned reinforcement - inactives3.64.011.11.5-3.32.2-0.50.62.62.1-1.6
Conditioned locomotion2.22.79.32.5-3.1-0.4-2.10.20.9-0.2-0.3
Patch foraging indifference point 0 sec1.93.16.5-2.20.81.92.52.4-1.1-0.41.3
Patch foraging indifference point AUC0.40.51.1-0.41.0-0.90.00.0-0.9-0.80.4
Delay disc. indifference point, 0s delay3.33.68.5-2.92.42.22.81.1-0.40.80.1
Delay disc. indifference point, 16s delay1.41.43.11.3-1.0-1.5-1.8-0.0-0.7-1.50.7
Delay disc. indifference point, 2s delay0.91.02.0-1.10.01.41.11.1-0.6-0.41.2
Delay disc. indifference point, 24s delay0.60.61.50.7-0.8-0.5-0.70.6-0.7-1.20.9
Delay disc. indifference point, 4s delay0.00.10.2-0.20.10.20.4-0.20.20.3-0.1
Delay disc. indifference point, 8s delay2.22.26.4-1.60.31.81.62.5-0.8-0.61.3
Indifference point function ln k3.85.411.80.6-2.63.40.80.53.03.2-1.9
Indifference point function log k3.85.411.80.6-2.63.40.80.53.03.2-1.9
Patch foraging total patch changes 0 sec2.03.26.6-2.20.62.12.52.6-1.1-0.51.4
Patch foraging total patch changes 12 sec0.60.81.5-0.71.2-0.90.50.6-1.2-1.10.8
Patch foraging total patch changes 18 sec1.21.53.2-1.41.8-0.21.51.1-1.3-1.01.0
Patch foraging total patch changes 24 sec1.21.55.80.80.8-2.4-1.5-1.4-0.5-0.7-0.2
Patch foraging total patch changes 6 sec0.60.81.9-0.50.2-0.40.51.0-1.3-1.41.2
Patch foraging time to switch 0 sec4.46.821.62.2-0.1-4.6-3.1-1.6-1.9-3.21.5
Patch foraging water rate 0 sec1.11.85.2-1.30.52.31.70.60.91.6-0.7
Patch foraging water rate 12 sec3.65.619.6-1.6-0.74.42.92.21.72.4-0.7
Patch foraging water rate 18 sec1.72.39.5-0.8-1.03.11.71.50.91.3-0.2
Patch foraging water rate 24 sec0.71.02.6-0.6-0.11.61.00.11.01.4-0.8
Patch foraging water rate 6 sec3.34.910.41.7-2.11.1-0.5-1.23.23.2-2.9
Seeking ratio, delayed vs. immediate footshock3.74.39.5-3.02.22.63.11.7-0.50.70.3
Distance traveled before self-admin3.33.512.8-1.80.13.61.91.41.22.0-0.9
Distance traveled after self-admin5.05.613.5-3.72.73.33.01.6-0.41.30.0
Extensor digitorum longus weight0.00.10.40.0-0.30.50.2-0.10.50.6-0.3
Bone: elastic displacement1.11.33.1-1.20.11.31.61.7-0.8-0.60.8
Bone: elastic work1.21.65.1-1.4-0.22.31.81.30.20.70.1
Bone: endosteal estimation1.94.17.61.3-1.2-0.1-1.4-2.82.52.7-2.5
Bone: endosteal perimeter1.12.25.20.8-1.51.0-0.3-1.12.12.3-1.9
Epididymis fat weight0.40.92.30.8-0.5-1.2-0.80.6-0.9-1.51.1
Delta time in closed arm before/after self-admin0.30.21.1-0.51.0-0.50.0-0.4-0.4-0.20.2
Delta time in open arm before/after self-admin1.31.24.00.1-1.42.00.31.21.01.1-0.7
Diff in mean of infusions in LGA sessions3.53.910.4-2.20.23.22.92.6-0.30.20.8
Delay discount exponential model param1.92.04.71.5-0.3-1.5-1.5-2.21.10.9-1.5
Extinction: sum of active levers before priming2.72.75.8-2.31.32.22.41.6-0.40.30.6
Active lever presses in extinction session 61.91.84.71.8-1.0-1.9-2.2-0.8-0.5-1.00.3
Bone: final force1.01.53.00.9-1.20.4-0.6-1.21.71.7-1.5
Bone: final moment1.11.84.10.7-1.20.7-0.4-1.21.92.0-1.7
Food consumed during 24 hour testing period1.01.24.10.5-2.01.40.60.91.21.0-0.3
Glucose1.01.52.6-1.50.61.11.61.5-1.1-0.71.4
Heart weight2.63.712.5-0.3-2.23.51.82.11.51.6-0.4
Delay discount hyperbolic model param1.61.73.51.5-0.3-1.5-1.5-1.90.90.6-1.4
Intermittent access intake day 1-15 change2.12.17.21.0-2.71.90.11.31.40.9-0.3
Intermittent access intake escalation2.12.08.81.5-3.01.2-0.51.01.30.7-0.3
Intermittent access intake escalation 21.11.13.80.8-1.91.30.10.71.20.9-0.3
Intermitt. access day 1 inactive lever presses6.56.916.54.0-4.1-0.9-3.7-0.72.10.7-1.7
Intermitt. access day 15 inactive lever presses6.26.815.33.9-3.3-1.8-3.6-1.72.10.9-2.0
Intermitt. access escalation Index1.41.23.1-0.90.00.90.91.8-1.0-1.11.4
Intermittent access day 1 total infusions0.60.61.31.0-0.7-0.6-1.2-0.80.60.4-0.9
Intermittent access day 15 total infusions2.83.214.32.3-3.80.9-1.30.91.50.5-0.5
Intermittent access terminal intake (last 3 days)2.02.28.42.2-2.90.1-1.3-0.11.40.6-0.8
Intermittent access total infusions2.02.27.02.1-2.6-0.1-1.7-0.21.40.6-1.0
Intermittent access day 1 locomotion0.90.92.61.0-1.60.6-1.10.21.00.6-0.8
Intermittent access day 15 total locomotion2.62.810.11.0-3.22.4-0.02.11.10.50.0
Intermittent access total locomotion1.92.27.11.8-2.70.8-1.40.31.50.9-1.0
Intermittent access standard deviation2.02.16.22.3-2.5-1.0-1.80.20.2-0.80.4
Left kidney weight1.85.010.21.7-2.81.7-0.4-0.73.23.0-2.5
Right kidney weight1.64.412.01.9-3.51.8-0.7-0.02.82.3-1.6
Cocaine induced anxiety1.21.43.60.1-0.71.40.4-0.21.61.9-1.4
Post-drug Anxiety2.32.55.21.8-0.6-2.1-2.3-2.20.70.3-1.0
Baseline Anxiety3.33.511.71.9-0.1-3.4-2.5-1.9-0.8-1.50.4
Tail length1.75.017.4-0.7-2.24.22.32.71.51.7-0.0
Length with tail1.03.88.02.0-2.80.9-0.6-0.72.72.4-1.9
Length without tail1.73.76.22.3-1.0-2.2-2.2-2.51.61.2-2.0
Times rat made contact with spout0.60.62.1-0.91.40.31.00.8-0.5-0.30.5
Lifetime Intake0.91.03.71.4-1.90.1-1.10.10.90.4-0.7
Liver weight, left1.82.86.92.1-0.7-2.6-2.5-1.90.0-0.8-0.2
Liver weight, right0.40.71.71.1-0.8-1.3-1.2-0.5-0.1-0.50.1
Locomotor activity0.20.40.9-0.71.0-0.20.10.1-0.8-0.60.8
Locomotor testing distance0.20.41.0-0.31.0-0.5-0.6-1.0-0.4-0.30.3
Locomotor testing rearing0.30.51.5-0.10.9-0.3-0.6-1.20.40.6-0.6
Locomotion in novel chamber1.21.53.4-1.61.80.20.80.6-1.5-1.21.2
Locomotion in novel chamber post-restriction1.11.32.8-1.71.50.21.31.0-1.1-0.60.9
Fecal boli incidents, locomotor time 10.20.20.5-0.60.10.70.60.30.40.6-0.3
Change in fecal boli incidents, locomotor task2.62.54.0-1.91.80.21.30.9-2.0-1.61.9
Time >=10cm from walls, locomotor time 10.30.30.70.4-0.2-0.6-0.50.8-0.5-0.80.6
Bouts of movement, locomotor time 13.43.710.3-2.30.73.22.82.10.31.00.0
Total resting periods, locomotor time 11.51.63.8-1.80.82.01.91.3-0.10.40.3
Rest time, locomotor task time 11.71.85.00.80.1-1.2-1.2-2.21.41.3-1.7
Distance moved, locomotor task time 10.60.71.7-0.6-0.00.80.51.3-0.9-0.81.0
Vertical activity count, locomotor time 14.74.98.8-2.81.12.72.73.0-1.6-0.92.0
Time >=10cm from walls, locomotor time 21.01.14.00.20.7-2.0-0.7-0.5-1.0-1.20.7
Bouts of movement, locomotor time 20.10.10.6-0.40.8-0.30.30.1-0.20.1-0.1
Total resting periods, locomotor time 20.30.41.5-0.81.2-0.00.70.2-0.20.2-0.2
Rest time, locomotor task time 21.21.43.5-1.81.91.01.60.4-0.30.40.0
Distance moved, locomotor task time 20.00.00.0-0.0-0.1-0.10.0-0.0-0.1-0.10.1
Vertical activity count, locomotor time 21.01.12.4-1.60.71.41.31.3-0.5-0.10.6
Light reinforcement 10.71.23.3-1.71.01.51.80.5-0.10.6-0.0
Light reinforcement 20.30.41.0-0.40.5-0.50.2-0.2-1.0-1.00.8
Bone: marrow area1.94.17.91.3-1.2-0.1-1.4-2.82.52.7-2.6
Bone: maximum diameter0.61.02.00.1-1.41.40.70.21.21.4-0.8
Bone: maximum force0.91.63.40.8-1.30.7-0.3-1.21.81.8-1.5
Bone: maximum moment1.11.94.60.5-1.21.0-0.1-1.21.92.1-1.6
Mean time between licks in bursts0.91.22.6-1.61.20.81.10.7-1.3-0.91.1
Mean num. licks in bursts0.50.63.2-1.11.8-0.00.6-0.4-0.5-0.10.0
Cd content in liver1.01.14.4-1.0-0.22.11.21.00.60.9-0.1
Co content in liver0.50.62.00.9-1.40.7-0.30.60.90.5-0.2
Cu content in liver1.11.42.31.5-0.5-1.0-1.5-1.41.10.7-1.3
Fe content in liver0.20.20.70.7-0.8-0.3-0.5-0.30.40.1-0.1
K content in liver0.10.10.4-0.00.50.1-0.0-0.30.20.3-0.6
Mg content in liver0.10.10.20.10.5-0.4-0.4-0.2-0.4-0.5-0.0
Mn content in liver0.10.20.6-0.10.3-0.3-0.10.0-0.6-0.80.3
Na content in liver0.80.91.8-0.61.3-0.90.20.3-1.3-1.30.7
Rb content in liver0.50.61.90.50.2-0.7-0.9-1.40.40.4-0.9
Se content in liver1.31.53.2-0.91.3-0.50.40.8-1.8-1.81.5
Sr content in liver9.28.515.6-3.92.72.13.53.0-2.8-1.82.8
Zn content in liver0.80.82.11.3-0.8-1.4-1.3-0.4-0.2-0.70.2
Bone: minimum diameter1.52.77.70.4-0.90.90.3-1.42.22.8-2.4
Time in familiar zone, hab. session 12.12.04.8-1.10.12.01.40.11.42.2-1.4
Time in novel zone, hab. session 12.32.26.51.5-0.3-2.5-1.8-1.2-0.9-1.70.7
Total zone transitions, hab. session 10.81.13.1-0.10.40.10.1-1.11.21.8-1.7
Total locomotion distance, hab. session 10.81.12.3-1.30.81.41.51.00.41.1-0.6
Locomotion velocity, hab. session 10.50.71.1-1.00.51.01.10.90.30.9-0.5
Time in familiar zone, hab. session 21.81.82.81.7-1.5-0.6-1.4-1.11.61.2-1.5
Time in novel zone, hab. session 20.60.61.2-0.50.9-0.60.1-0.1-1.1-1.10.9
Total zone transitions, hab. session 21.21.54.5-0.4-0.11.40.80.01.42.1-1.7
Total locomotion distance, hab. session 21.31.73.9-1.80.81.82.01.6-0.20.60.1
Locomotion velocity, hab. session 21.72.35.1-2.11.02.02.31.8-0.30.50.3
Novel to familiar place preference ratio0.50.51.3-1.10.90.71.00.4-0.30.10.3
Novelty place preference0.20.20.6-0.70.60.60.70.10.00.3-0.0
Time in novel zone, NPP test0.10.10.3-0.60.40.40.5-0.00.10.3-0.1
Total zone transitions, NPP test0.30.40.9-0.70.10.81.00.60.20.6-0.2
Total locomotion distance, NPP test1.01.43.5-1.30.21.61.81.9-0.20.30.3
Locomotion velocity, NPP test1.21.74.2-1.50.31.82.01.9-0.10.50.1
Intraocular pressure0.20.30.70.7-0.1-0.6-0.8-0.70.40.3-0.6
Delta distance traveled before/after self-admin1.51.73.3-1.81.70.71.41.0-1.3-0.71.2
Delta ambulatory time before/after self-admin1.61.83.4-1.81.41.01.71.3-1.3-0.71.2
Parametrial fat weight3.05.911.8-1.81.8-0.71.12.1-3.3-3.43.4
Pavlov. Cond. lever latency0.10.10.50.3-0.2-0.3-0.2-0.70.1-0.1-0.0
Pavlov. Cond. magazine entry latency0.50.71.6-0.81.2-0.20.30.5-1.1-0.90.8
Pavlov. Cond. change in total contacts0.30.40.9-0.70.60.60.61.0-0.4-0.30.5
Pavlov. Cond. index score0.40.50.9-0.80.90.40.40.9-0.7-0.50.6
Pavlov. Cond. latency score0.40.61.4-0.90.70.50.61.2-0.7-0.50.7
Pavlov. Cond. lever contacts0.00.10.40.1-0.00.1-0.10.6-0.0-0.10.0
Pavlov. Cond. magazine entry number0.50.62.01.0-1.4-0.1-0.4-0.40.80.5-0.5
Pavlov. Cond. intertrial magazine entries0.30.30.9-0.4-0.21.00.8-0.00.40.7-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.40.7-0.70.80.30.30.8-0.7-0.60.6
Pavlov. Cond. response bias0.10.20.4-0.10.7-0.5-0.40.1-0.4-0.40.2
Pavlov. Cond. lever latency2.63.58.52.9-2.1-1.1-2.6-1.31.70.8-1.5
Pavlov. Cond. magazine entry latency1.51.82.6-1.61.20.21.51.1-1.6-1.21.6
Pavlov. Cond. change in total contacts1.11.43.9-1.91.21.42.00.4-0.10.8-0.1
Pavlov. Cond. index score1.21.63.9-2.01.50.71.80.7-1.2-0.51.0
Pavlov. Cond. latency score1.72.14.4-2.11.40.81.91.2-1.4-0.81.3
Pavlov. Cond. lever contacts1.21.64.4-2.11.70.61.90.6-1.0-0.20.7
Pavlov. Cond. magazine entry number0.70.81.71.3-1.10.0-1.0-0.41.10.7-1.0
Pavlov. Cond. intertrial magazine entries3.14.17.81.9-1.3-0.2-1.7-2.12.62.4-2.8
Pavlov. Cond. lever-magazine prob. diff.1.11.43.5-1.91.30.71.70.7-1.0-0.40.8
Pavlov. Cond. response bias0.60.82.4-1.51.40.31.3-0.2-0.40.30.1
Time in closed arm before self-admin1.21.36.11.7-2.50.4-0.50.30.90.3-0.6
Time in closed arm after self-admin0.50.51.21.1-0.8-0.9-0.9-0.60.1-0.3-0.2
Time in open arm before self-admin2.12.310.1-1.93.2-0.91.0-1.0-1.1-0.30.4
Time in open arm after self-admin0.80.83.0-1.51.70.31.10.0-0.40.20.0
Bone: periosteal estimation1.22.45.80.6-1.20.5-0.3-1.82.02.4-2.0
Bone: periosteal perimeter1.21.94.80.5-0.60.5-0.1-1.61.82.2-2.0
Bone: post-yield work2.12.88.11.7-0.8-1.2-1.7-2.81.61.4-1.5
Progressive ratio test 1 active lever presses0.80.82.2-0.30.30.60.0-0.71.11.5-1.4
Progressive ratio test 1 breakpoint0.70.71.9-0.20.20.60.0-0.61.01.4-1.4
Progressive ratio test 1 inactive lever presses3.03.35.61.9-1.90.2-1.7-1.12.32.0-2.4
Progressive ratio test 2 active lever presses1.51.66.61.5-2.60.9-0.80.51.30.7-0.7
Progressive ratio test 2 breakpoint1.82.07.81.8-2.80.7-1.10.31.50.8-0.9
Progressive ratio test 2 inactive lever presses2.83.39.52.0-3.11.0-1.30.12.21.6-1.6
Incentive Sensitization - Responses5.15.218.13.2-4.30.4-2.2-0.12.31.1-1.4
Incentive Sensitization - Breakpoint4.44.515.43.1-3.9-0.0-2.2-0.21.90.8-1.2
Sum of active levers in priming session hrs 5-63.83.710.3-1.3-1.13.22.23.1-0.2-0.21.3
Progressive ratio1.92.25.0-2.22.21.02.11.1-0.9-0.00.4
Food seeking constrained by brief footshock17.821.949.2-6.84.06.57.04.1-0.91.61.0
Seeking ratio, punishment vs. effort2.02.48.2-1.90.42.92.11.20.51.10.1
Retroperitoneal fat weight3.210.420.8-2.62.3-0.71.42.9-4.4-4.54.6
Reaction time number correct1.31.84.8-2.22.01.31.41.0-0.9-0.10.5
Reaction time mean minus median0.30.41.10.9-0.1-1.1-0.9-0.60.2-0.1-0.2
Reaction time mean minus median AUC0.70.92.80.90.5-1.7-1.3-1.20.0-0.2-0.4
Reaction time num false alarms0.30.41.9-0.4-0.20.90.31.4-0.1-0.10.4
Reaction time num false alarms AUC0.91.23.3-1.40.81.31.01.8-0.6-0.20.7
Reaction time trials correct on left1.31.84.8-2.22.01.31.41.0-0.9-0.10.5
Reaction time trials on left1.21.84.7-2.21.91.31.41.0-0.9-0.10.5
Reaction time mean2.33.28.22.9-2.3-1.4-2.6-1.01.30.4-1.0
Reaction time mean AUC2.02.77.02.6-2.1-1.5-2.5-0.80.8-0.1-0.5
Median of all reaction times1.82.46.32.5-2.2-0.9-2.2-0.71.20.3-0.8
Reaction time omissions0.00.10.1-0.20.30.1-0.10.3-0.2-0.20.3
Reaction time false alarm rate0.20.31.7-0.1-0.40.70.21.3-0.1-0.20.4
Reaction time premature initiation rate0.10.10.40.1-0.10.20.20.6-0.1-0.30.5
Reaction time premature initiations0.50.71.1-1.01.00.70.91.0-0.6-0.40.8
Std. dev. reaction times1.11.54.02.0-1.5-1.0-1.9-0.50.80.1-0.6
Reaction time trials completed1.21.84.7-2.21.91.31.41.0-0.9-0.10.5
Reaction time trials AUC1.21.74.3-2.11.91.21.31.0-0.9-0.10.5
Run reversals in cocaine runway, females1.00.94.21.3-2.1-0.1-0.80.90.3-0.40.3
Run reversals in cocaine runway, males0.60.61.90.70.1-1.2-0.7-1.40.30.2-0.6
Latency to leave start box in cocaine runway0.91.03.70.6-1.91.40.30.80.90.4-0.2
Latency to leave start box in cocaine runway, F0.80.92.8-0.2-1.21.70.91.20.40.20.2
Latency to leave start box in cocaine runway, M0.90.91.71.3-1.3-0.4-0.8-0.81.00.7-0.9
Std. dev. time between licks in bursts0.70.82.5-0.9-0.51.61.30.80.20.60.1
Total sessions with >9 infusions2.62.85.12.0-1.6-0.9-2.3-1.51.71.2-1.9
Short access day 1 total inactive lever presses2.93.27.42.7-2.0-1.9-2.5-1.51.00.1-0.9
Short access day 10 total inactive lever presses1.92.15.52.3-2.0-1.1-1.8-0.91.10.3-0.9
Short access day 1 total infusions0.10.10.3-0.10.4-0.10.1-0.30.20.4-0.6
Short access day 10 total infusions0.60.72.01.1-0.6-1.1-1.4-0.70.1-0.3-0.4
Short access total infusions0.30.30.6-0.80.50.30.50.7-0.6-0.40.4
Short access day 1 locomotion1.61.74.21.6-0.9-1.1-2.1-1.51.00.7-1.3
Short access day 10 total locomotion1.51.74.50.8-2.11.9-0.51.21.20.9-0.7
Short access total locomotion0.90.93.7-0.8-0.31.90.71.50.00.30.1
One hour access (0.3 mA shock)4.35.115.63.1-3.90.3-2.2-0.22.31.3-1.7
Compulsive drug intake1.01.02.41.1-1.60.7-0.20.31.31.0-0.9
One hour access (shock baseline)4.04.611.33.4-3.1-1.7-3.1-1.21.2-0.1-0.9
Social response proportion2.32.510.72.3-3.30.0-1.30.31.30.3-0.4
Social responses3.34.28.72.8-2.9-0.4-1.9-1.22.41.6-2.0
Social time2.63.49.2-0.5-1.13.01.51.02.12.6-1.5
Soleus weight0.30.72.0-0.8-0.11.41.21.1-0.10.10.6
Bone: stiffness1.52.34.01.7-2.00.1-1.2-1.31.91.6-1.5
Tibialis anterior weight1.24.16.6-2.62.00.71.91.7-2.4-1.92.4
Time to tail flick, vehicle, before self-admin0.20.20.60.2-0.50.6-0.10.10.80.7-0.3
Time to tail flick, vehicle, after self-admin2.42.67.82.6-2.8-0.5-2.0-0.51.30.3-0.5
Time to tail flick, test, before self-admin7.57.419.1-3.41.24.44.12.60.51.8-0.2
Time to tail flick, test, after self-admin0.10.10.20.3-0.2-0.2-0.40.00.0-0.1-0.2
Delta time to tail flick, vehicle, before/after SA1.01.02.91.7-1.5-1.0-1.2-0.40.2-0.50.1
Delta time to tail flick, test, before/after SA4.03.68.82.7-1.4-2.8-3.0-1.5-0.1-1.1-0.1
Tibia length1.54.39.91.2-1.70.9-0.5-1.42.93.1-2.9
Ambulatory time before self-admin1.81.95.6-1.40.52.41.20.71.01.8-1.0
Ambulatory time after self-admin5.05.516.0-3.11.54.03.02.00.21.7-0.2
Bone: tissue strength3.53.48.3-2.10.22.92.62.6-0.30.30.9
Total heroin consumption1.61.83.4-1.50.81.01.71.9-1.3-1.01.4
Bone: trabecular number0.60.93.7-1.51.90.11.1-0.2-0.50.20.0
Bone: trabecular spacing0.10.10.2-0.40.3-0.10.30.2-0.4-0.40.2
Bone: trabecular thickness0.20.20.60.5-0.2-0.4-0.7-0.80.1-0.1-0.0
Bone: trabecular tissue density1.82.65.41.7-1.0-2.3-2.0-0.6-1.0-2.11.1
Water consumed over 24 hours0.81.02.7-0.2-0.91.61.00.41.21.3-0.3
Number of responses in last shaping day1.81.94.52.1-2.1-0.9-2.0-0.70.8-0.0-0.3