Hub : Genes

Zdhhc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Zdhhc1 0.11 0.08 4.3e-04 0.04 0.04 0.04 0.03 5.4e-04 1.8e-04 5.8e-04 1.3e-03
2 Adipose isoform ratio XM_063277915.1 0.03 0.03 5.2e-04 0.03 0.02 0.01 0.02 3.0e-04 2.0e-03 1.6e-02 1.4e-03
3 Adipose alternative TSS NM_001039099.1 0.11 0.08 8.6e-11 0.08 0.07 0.07 0.07 2.0e-09 1.4e-08 1.6e-08 1.3e-08
4 Adipose isoform ratio XM_017601227.3 0.04 0.03 1.2e-05 0.04 0.04 0.03 0.04 1.0e-05 5.8e-05 1.2e-04 7.7e-05
5 Adipose isoform ratio XM_063277920.1 0.15 0.1 0.0e+00 0.13 0.13 0.13 0.13 2.6e-14 4.1e-14 3.6e-14 3.0e-14
6 NAcc alternative TSS XM_063277920.1 0.03 0.03 2.7e-04 0.02 0.02 0.02 0.02 8.1e-04 1.1e-03 8.7e-04 7.1e-04
7 NAcc gene expression Zdhhc1 0.03 0.03 4.8e-03 0.01 0.01 0 0.01 5.1e-03 1.0e-02 8.6e-02 6.6e-03
8 NAcc mRNA stability Zdhhc1 0.03 0.03 9.0e-03 0.01 0.01 0.01 0.01 9.4e-03 3.0e-02 1.6e-02 2.7e-02
9 pVTA alternative TSS XM_063277920.1 0.04 0.04 8.8e-03 0.02 0.02 0.02 0.02 6.2e-03 6.8e-03 1.2e-02 1.0e-02
10 BLA gene expression Zdhhc1 0.06 0.07 4.3e-03 0.04 0.03 0.03 0.03 3.9e-03 9.5e-03 9.5e-03 1.3e-02
11 Liver mRNA stability Zdhhc1 0.03 0.03 8.3e-04 0.01 0.02 0.01 0.02 7.3e-03 2.1e-03 2.6e-02 3.4e-03
12 Adipose alternative TSS XM_063277920.1 0.17 0.1 0.0e+00 0.16 0.16 0.16 0.16 7.6e-17 2.3e-17 5.5e-17 3.5e-17
13 BLA mRNA stability Zdhhc1 0.06 0.05 7.4e-04 0.03 0.06 0.04 0.04 6.7e-03 6.9e-04 3.7e-03 2.7e-03
14 Adipose alternative TSS XM_063277917.1 0.02 0.02 2.4e-03 0.01 0.01 0 0.01 2.9e-02 8.0e-03 1.4e-01 6.0e-02
15 Adipose isoform ratio XM_017601226.3 0.1 0.07 1.2e-13 0.09 0.09 0.09 0.09 2.1e-10 1.8e-10 4.1e-10 2.5e-10
16 Liver gene expression Zdhhc1 0.13 0.08 1.4e-15 0.11 0.12 0.11 0.11 4.1e-12 8.3e-13 6.9e-12 3.2e-12
17 Adipose mRNA stability Zdhhc1 0.11 0.08 2.7e-11 0.07 0.08 0.07 0.07 3.0e-08 3.3e-09 5.3e-08 4.1e-08
18 Adipose alternative TSS XM_017601226.3 0.13 0.09 2.8e-15 0.1 0.11 0.11 0.11 2.3e-11 3.1e-12 8.2e-12 6.7e-12
19 Adipose gene expression Zdhhc1 0.2 0.11 0.0e+00 0.15 0.15 0.14 0.15 2.6e-16 1.4e-16 7.6e-16 1.3e-16
20 Adipose alternative TSS XM_017601226.3 0.11 0.09 1.5e-10 0.07 0.07 0.06 0.06 8.8e-08 2.0e-08 1.7e-07 1.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.10.4-0.6-0.50.5-0.50.5-0.30.5-0.50.3-0.30.3-0.30.30.30.20.2-0.20.2-0.20.2
Area under the delay curve0.00.00.10.20.0-0.00.0-0.00.1-0.10.1-0.10.1-0.00.10.00.00.0-0.00.0-0.0-0.1-0.1
BMI with tail0.00.10.2-0.40.1-0.10.1-0.1-0.20.4-0.30.3-0.40.3-0.20.30.30.30.2-0.20.2-0.30.2
BMI without tail0.00.10.30.50.6-0.60.6-0.60.3-0.20.2-0.50.4-0.00.10.00.00.00.00.00.0-0.1-0.0
Body weight0.31.31.7-1.1-1.11.1-1.11.1-1.21.1-1.30.9-1.11.2-1.21.21.21.21.2-1.21.2-1.21.2
Weight adjusted by age0.00.00.10.0-0.00.0-0.00.0-0.20.1-0.1-0.00.00.1-0.10.10.10.10.1-0.10.1-0.10.2
Bone surface1.32.63.7-1.9-1.71.7-1.71.7-1.51.8-1.71.6-1.61.6-1.61.51.51.51.5-1.51.5-1.41.5
Bone volume1.02.03.1-1.8-1.41.4-1.41.4-1.31.5-1.51.4-1.41.4-1.41.31.31.31.4-1.41.3-1.31.4
Breakpoint value in progressive ratio session1.12.12.61.11.1-1.11.1-1.11.5-1.41.5-1.31.3-1.61.5-1.6-1.6-1.6-1.61.6-1.61.6-1.6
Number of licking bursts0.30.91.2-1.1-1.01.0-1.01.0-0.91.0-1.01.0-1.01.0-1.01.01.00.90.9-0.90.9-0.90.9
Context. condit. distance diff. score0.00.00.1-0.10.2-0.20.2-0.20.2-0.00.3-0.0-0.0-0.20.1-0.2-0.2-0.2-0.10.1-0.10.3-0.1
Locomotion velocity, session 10.00.00.10.0-0.10.1-0.10.1-0.20.30.10.2-0.20.2-0.10.20.20.20.2-0.10.1-0.20.1
Locomotion distance, session 10.10.20.50.60.5-0.50.5-0.50.4-0.30.7-0.30.4-0.30.3-0.3-0.3-0.3-0.30.3-0.30.2-0.3
Locomotion velocity, session 20.70.92.01.21.1-1.11.1-1.11.0-0.91.4-0.90.8-0.80.8-0.9-0.9-0.8-0.70.7-0.70.7-0.7
Locomotion distance, session 20.10.20.80.70.6-0.60.6-0.60.5-0.30.9-0.30.3-0.40.3-0.3-0.3-0.3-0.20.3-0.30.3-0.2
Locomotion velocity, session 30.30.30.50.50.5-0.50.5-0.50.6-0.70.5-0.50.5-0.60.6-0.5-0.5-0.6-0.60.6-0.60.6-0.6
Locomotion distance, session 30.00.00.10.20.2-0.20.2-0.20.2-0.30.0-0.20.3-0.10.1-0.1-0.1-0.1-0.10.0-0.00.20.0
Stereotopy head waving bouts, day 30.10.10.2-0.1-0.40.4-0.40.4-0.30.3-0.50.4-0.40.3-0.30.30.40.40.3-0.30.3-0.40.3
Stereotopy head waving duration, day 30.50.71.0-0.8-0.80.8-0.80.8-0.80.8-0.90.9-1.00.8-0.70.80.80.80.7-0.70.7-0.80.7
Locomotion velocity, session 70.00.00.1-0.30.1-0.10.1-0.10.1-0.00.20.1-0.1-0.10.1-0.2-0.2-0.2-0.20.2-0.20.2-0.2
Locomotion distance, session 70.00.00.1-0.10.1-0.10.1-0.10.3-0.10.1-0.20.1-0.20.1-0.2-0.2-0.2-0.20.2-0.20.3-0.1
Stereotopy head waving bouts, day 70.20.20.6-0.8-0.60.6-0.60.6-0.50.4-0.70.6-0.60.4-0.40.40.40.30.3-0.30.3-0.30.3
Stereotopy head waving duration, day 70.60.71.3-1.1-1.01.0-1.01.0-1.00.7-1.20.9-0.90.7-0.70.80.70.70.6-0.60.6-0.60.6
Locomotion velocity, session 80.00.00.1-0.30.1-0.10.1-0.1-0.00.10.2-0.10.1-0.20.2-0.2-0.2-0.3-0.30.3-0.30.3-0.4
Locomotion distance, session 80.40.51.00.60.9-0.90.9-0.90.8-0.51.0-0.50.6-0.70.6-0.7-0.7-0.7-0.60.6-0.60.8-0.6
Degree of sensitization distance0.00.00.1-0.2-0.10.1-0.10.10.00.3-0.10.1-0.20.1-0.10.10.10.10.1-0.10.1-0.00.1
Degree of sensitization stereotypy0.30.40.7-0.9-0.70.7-0.70.7-0.70.5-0.70.7-0.70.5-0.50.50.50.50.4-0.40.4-0.50.4
Conditioned locomotion2.22.63.2-1.8-1.51.5-1.51.5-1.51.8-1.51.6-1.61.6-1.71.61.61.61.7-1.71.7-1.41.7
Cocaine response after cond. corrected0.20.30.5-0.6-0.50.5-0.50.5-0.60.6-0.70.7-0.60.6-0.40.60.60.60.4-0.40.4-0.70.3
Cocaine response after cond. not corrected0.00.00.10.0-0.10.1-0.10.1-0.10.0-0.20.1-0.00.00.10.10.10.0-0.10.1-0.1-0.2-0.2
Cocaine response before conditioning1.11.42.11.41.0-1.01.0-1.01.2-1.41.1-1.41.3-1.21.2-1.2-1.2-1.2-1.21.2-1.11.0-1.2
Saline control response4.25.86.6-2.2-2.22.2-2.22.2-2.32.5-2.12.6-2.62.5-2.52.52.52.52.5-2.52.5-2.42.5
Bone: connectivity density0.00.00.1-0.1-0.00.0-0.00.00.2-0.00.1-0.20.2-0.20.2-0.2-0.3-0.3-0.30.3-0.30.3-0.3
Bone: cortical apparent density0.81.21.60.71.0-1.01.0-1.01.0-1.10.7-1.21.2-1.11.1-1.1-1.1-1.2-1.21.2-1.21.3-1.2
Bone: cortical area0.30.50.8-0.9-0.50.5-0.50.5-0.70.8-0.70.9-0.90.7-0.70.70.70.70.7-0.70.7-0.70.7
Bone: cortical porosity0.20.20.50.50.7-0.70.7-0.70.5-0.40.4-0.30.3-0.40.3-0.4-0.4-0.4-0.30.3-0.30.5-0.2
Bone: cortical porosity0.20.20.50.50.7-0.70.7-0.70.5-0.40.4-0.30.3-0.40.3-0.4-0.4-0.4-0.30.3-0.30.5-0.3
Bone: cortical thickness0.10.10.5-0.7-0.30.3-0.30.3-0.50.4-0.50.5-0.50.4-0.30.30.30.30.3-0.30.2-0.30.3
Bone: cortical thickness0.00.00.1-0.30.2-0.20.2-0.2-0.20.2-0.10.2-0.20.1-0.30.10.10.10.2-0.30.3-0.10.3
Bone: cortical tissue density0.81.31.70.71.0-1.01.0-1.01.1-1.20.7-1.21.2-1.11.2-1.1-1.1-1.2-1.31.3-1.31.3-1.3
Condit. Reinf. active minus inactive responses4.24.85.32.12.2-2.22.2-2.22.2-2.12.3-2.22.1-2.22.2-2.2-2.2-2.2-2.22.2-2.22.3-2.2
Condit. Reinf. active-inactive response ratio3.84.04.91.82.0-2.02.0-2.01.9-2.01.9-2.12.0-2.02.0-2.0-2.0-2.0-2.02.0-2.02.2-2.0
Condit. Reinf. active responses2.93.74.81.92.0-2.02.0-2.02.0-1.92.2-1.91.8-1.91.9-1.9-1.9-1.9-1.81.8-1.81.9-1.8
Condit. Reinf. inactive responses0.10.20.40.50.5-0.50.5-0.50.4-0.50.6-0.40.4-0.40.4-0.4-0.4-0.4-0.40.4-0.40.4-0.3
Incentive salience index mean2.22.83.71.51.8-1.81.8-1.81.7-1.61.9-1.61.6-1.61.6-1.6-1.6-1.6-1.61.6-1.61.8-1.6
Condit. Reinf. lever presses0.20.20.60.30.6-0.60.6-0.60.4-0.30.8-0.40.3-0.40.4-0.5-0.5-0.5-0.40.5-0.50.6-0.5
Condit. Reinf. active minus inactive responses0.60.81.1-1.0-0.60.6-0.60.6-0.91.0-1.00.8-0.91.0-1.01.01.01.01.0-1.01.0-1.01.0
Condit. Reinf. active-inactive response ratio0.40.61.0-0.9-0.70.7-0.70.7-0.80.8-1.00.6-0.70.8-0.80.80.80.80.8-0.80.8-0.90.8
Condit. Reinf. active responses0.30.50.7-0.7-0.20.2-0.20.2-0.60.8-0.70.6-0.70.8-0.80.80.80.80.8-0.80.8-0.70.8
Condit. Reinf. inactive responses0.20.30.60.50.8-0.80.8-0.80.5-0.50.6-0.30.3-0.40.3-0.4-0.4-0.3-0.30.3-0.30.6-0.2
Condit. Reinf. lever presses2.23.23.71.61.9-1.91.9-1.91.8-1.81.7-1.81.7-1.81.7-1.8-1.8-1.8-1.71.6-1.71.8-1.6
Condit. Reinf. lever reinforcers received0.10.10.1-0.30.3-0.30.3-0.3-0.10.3-0.20.2-0.20.3-0.30.30.30.30.3-0.30.3-0.20.4
Conditioned reinforcement - actives0.41.52.91.71.5-1.51.5-1.51.3-1.31.3-1.41.4-1.01.1-1.0-1.0-1.0-0.91.0-0.90.8-1.0
Conditioned reinforcement - inactives0.00.11.1-1.0-0.30.3-0.30.3-0.40.3-0.50.3-0.40.2-0.20.30.20.10.0-0.00.00.1-0.0
Conditioned locomotion0.60.81.9-1.4-0.80.8-0.80.8-1.01.0-1.10.9-1.00.9-0.90.90.90.80.8-0.80.8-0.90.8
Patch foraging indifference point 0 sec2.05.56.1-2.2-2.32.3-2.32.3-2.42.4-2.22.3-2.22.4-2.42.42.42.42.4-2.42.4-2.52.4
Patch foraging indifference point AUC1.22.83.4-1.7-1.51.5-1.51.5-1.41.6-1.71.8-1.71.7-1.81.71.71.71.8-1.81.8-1.71.8
Delay disc. indifference point, 0s delay0.70.81.21.10.8-0.80.8-0.81.0-0.91.0-1.01.0-0.91.0-0.9-0.8-0.9-0.90.9-0.90.6-1.0
Delay disc. indifference point, 16s delay0.10.10.50.3-0.20.2-0.20.2-0.20.2-0.00.1-0.10.4-0.40.40.50.50.5-0.50.5-0.70.5
Delay disc. indifference point, 2s delay0.20.31.1-1.1-0.60.6-0.60.6-0.50.6-0.50.6-0.60.4-0.40.40.40.30.3-0.20.3-0.20.2
Delay disc. indifference point, 24s delay0.00.00.00.1-0.10.1-0.10.1-0.10.1-0.1-0.20.20.1-0.10.10.10.10.1-0.10.1-0.20.2
Delay disc. indifference point, 4s delay0.30.30.50.30.3-0.30.3-0.30.5-0.50.4-0.60.6-0.60.6-0.5-0.6-0.6-0.70.7-0.70.6-0.7
Delay disc. indifference point, 8s delay0.00.00.10.2-0.00.0-0.00.00.1-0.1-0.00.0-0.0-0.00.00.10.10.00.00.00.0-0.1-0.0
Indifference point function ln k0.20.50.60.70.6-0.60.6-0.60.6-0.70.7-0.70.8-0.70.7-0.6-0.6-0.7-0.70.8-0.70.7-0.8
Indifference point function log k0.20.50.60.70.6-0.60.6-0.60.6-0.70.7-0.70.8-0.70.7-0.6-0.6-0.7-0.70.8-0.70.7-0.8
Patch foraging total patch changes 0 sec1.95.56.1-2.2-2.32.3-2.32.3-2.32.3-2.22.3-2.22.4-2.42.42.42.42.4-2.42.5-2.52.5
Patch foraging total patch changes 12 sec3.14.24.7-1.9-2.12.1-2.12.1-2.01.9-2.01.9-1.92.0-2.12.02.02.12.1-2.12.1-2.02.2
Patch foraging total patch changes 18 sec1.94.45.3-2.1-2.02.0-2.02.0-2.02.0-2.12.0-2.02.1-2.22.12.12.12.2-2.22.2-2.12.3
Patch foraging total patch changes 24 sec0.20.61.2-1.0-1.11.1-1.11.1-0.90.6-0.80.5-0.50.6-0.70.60.60.60.6-0.70.6-0.60.7
Patch foraging total patch changes 6 sec1.93.33.6-1.9-1.91.9-1.91.9-1.71.8-1.81.8-1.71.8-1.81.81.81.81.8-1.81.8-1.71.8
Patch foraging time to switch 0 sec0.41.72.41.31.0-1.01.0-1.01.1-1.41.3-1.51.5-1.31.3-1.3-1.3-1.3-1.41.4-1.41.3-1.4
Patch foraging water rate 0 sec0.83.13.8-1.5-1.81.8-1.81.8-1.61.6-1.81.8-1.81.7-1.71.81.81.81.8-1.81.8-1.91.8
Patch foraging water rate 12 sec0.10.41.0-0.6-1.01.0-1.01.0-0.50.3-0.80.3-0.40.5-0.50.50.50.50.5-0.50.5-0.50.5
Patch foraging water rate 18 sec0.10.30.7-0.7-0.90.9-0.90.9-0.50.2-0.70.0-0.10.3-0.40.30.30.30.3-0.40.4-0.20.4
Patch foraging water rate 24 sec0.00.10.20.1-0.40.4-0.40.4-0.0-0.1-0.30.3-0.40.2-0.20.20.20.20.2-0.30.3-0.30.3
Patch foraging water rate 6 sec0.91.32.2-1.5-1.31.3-1.31.3-1.11.0-1.41.0-1.11.0-1.11.01.01.01.0-1.11.1-1.01.1
Seeking ratio, delayed vs. immediate footshock2.23.23.9-1.8-1.71.7-1.71.7-1.91.8-1.72.0-2.01.8-1.71.81.81.81.8-1.71.8-1.81.7
Distance traveled before self-admin0.61.37.6-2.8-1.21.2-1.21.2-1.11.3-1.41.3-1.10.8-1.00.70.60.60.6-0.70.6-0.20.7
Distance traveled after self-admin0.10.10.6-0.8-0.50.5-0.50.5-0.30.3-0.50.4-0.20.3-0.30.30.30.20.2-0.30.3-0.20.3
Extensor digitorum longus weight0.62.53.21.51.5-1.51.5-1.51.5-1.81.4-1.81.7-1.61.5-1.7-1.7-1.6-1.51.5-1.51.8-1.4
Bone: elastic displacement1.51.92.3-1.3-1.41.4-1.41.4-1.41.3-1.51.4-1.41.4-1.31.41.41.41.4-1.41.4-1.51.3
Bone: elastic work0.60.71.0-0.9-0.80.8-0.80.8-0.80.9-1.00.9-0.90.9-0.80.90.90.90.8-0.80.8-0.90.8
Bone: endosteal estimation0.10.10.3-0.2-0.20.2-0.20.2-0.20.3-0.40.3-0.30.4-0.40.40.40.50.5-0.50.5-0.30.5
Bone: endosteal perimeter0.20.40.7-0.5-0.30.3-0.30.3-0.40.7-0.40.7-0.70.7-0.70.70.70.70.8-0.80.8-0.70.8
Epididymis fat weight1.67.99.0-2.9-2.82.8-2.82.8-2.92.7-3.02.5-2.82.8-2.92.82.72.82.8-2.92.9-2.62.9
Delta time in closed arm before/after self-admin0.20.10.30.1-0.40.4-0.40.4-0.40.2-0.20.4-0.50.4-0.30.40.40.40.4-0.40.4-0.50.4
Delta time in open arm before/after self-admin0.10.10.7-0.8-0.10.1-0.10.1-0.00.2-0.10.1-0.1-0.30.2-0.3-0.3-0.4-0.50.5-0.50.8-0.5
Diff in mean of infusions in LGA sessions0.20.40.70.30.4-0.40.4-0.40.7-0.50.7-0.40.4-0.80.7-0.8-0.8-0.8-0.80.8-0.80.8-0.8
Delay discount exponential model param0.00.00.1-0.3-0.10.1-0.10.1-0.20.2-0.20.1-0.20.1-0.10.10.10.10.1-0.10.1-0.00.1
Extinction: sum of active levers before priming0.60.91.31.11.1-1.11.1-1.11.0-1.11.0-0.70.7-0.91.0-0.9-0.9-0.9-0.90.9-0.90.7-0.9
Active lever presses in extinction session 60.00.00.20.30.2-0.20.2-0.20.4-0.10.00.2-0.00.1-0.10.10.10.10.1-0.10.1-0.20.1
Bone: final force0.81.31.61.01.3-1.31.3-1.31.2-1.11.2-1.01.0-1.11.1-1.2-1.2-1.2-1.11.1-1.11.2-1.0
Bone: final moment0.30.60.60.70.8-0.80.8-0.80.8-0.70.8-0.60.6-0.80.7-0.8-0.8-0.7-0.70.7-0.70.8-0.7
Food consumed during 24 hour testing period0.20.41.0-0.3-0.40.4-0.40.4-0.30.4-0.40.5-0.50.6-0.80.70.70.80.9-0.90.9-0.71.0
Glucose1.72.73.41.61.4-1.41.4-1.41.5-1.61.6-1.81.8-1.71.7-1.6-1.6-1.7-1.81.7-1.71.7-1.8
Heart weight0.00.00.10.10.2-0.20.2-0.20.0-0.20.0-0.30.4-0.20.2-0.1-0.1-0.2-0.30.3-0.30.2-0.3
Delay discount hyperbolic model param0.00.10.1-0.3-0.20.2-0.20.2-0.30.3-0.30.2-0.20.2-0.30.20.20.20.3-0.30.2-0.20.3
Intermittent access intake day 1-15 change0.52.94.72.21.9-1.91.9-1.91.9-1.91.6-1.92.0-1.51.5-1.5-1.5-1.4-1.41.4-1.41.2-1.4
Intermittent access intake escalation0.63.24.92.21.9-1.91.9-1.92.0-2.01.7-2.02.1-1.61.6-1.6-1.6-1.6-1.51.5-1.51.3-1.5
Intermittent access intake escalation 20.91.52.91.71.3-1.31.3-1.31.4-1.31.2-1.51.5-1.11.1-1.0-1.0-1.0-1.01.0-1.00.8-1.0
Intermitt. access day 1 inactive lever presses0.00.10.40.60.4-0.40.4-0.40.4-0.50.4-0.30.3-0.20.3-0.1-0.1-0.1-0.20.2-0.20.1-0.2
Intermitt. access day 15 inactive lever presses0.00.10.3-0.30.2-0.20.2-0.20.3-0.30.2-0.20.2-0.40.4-0.4-0.4-0.5-0.50.5-0.50.5-0.5
Intermitt. access escalation Index0.20.51.1-0.3-1.11.1-1.11.1-0.70.4-0.50.6-0.60.6-0.60.60.60.60.6-0.60.6-1.00.6
Intermittent access day 1 total infusions0.10.21.21.10.5-0.50.5-0.50.4-0.50.4-0.50.3-0.20.3-0.1-0.0-0.0-0.10.2-0.1-0.2-0.2
Intermittent access day 15 total infusions1.43.47.32.72.2-2.22.2-2.22.0-2.11.9-2.02.0-1.61.7-1.4-1.4-1.4-1.41.5-1.51.1-1.5
Intermittent access terminal intake (last 3 days)2.64.68.83.02.4-2.42.4-2.42.3-2.42.2-2.32.3-1.92.0-1.8-1.8-1.8-1.81.8-1.81.5-1.9
Intermittent access total infusions2.83.37.52.72.1-2.12.1-2.12.0-2.01.9-2.01.9-1.61.7-1.5-1.4-1.4-1.41.5-1.41.1-1.5
Intermittent access day 1 locomotion0.71.32.3-0.6-1.01.0-1.01.0-1.11.0-1.11.1-1.31.2-1.11.31.41.31.2-1.21.2-1.51.1
Intermittent access day 15 total locomotion0.00.20.6-0.2-0.20.2-0.20.2-0.30.4-0.60.3-0.30.5-0.40.60.60.60.5-0.40.5-0.80.4
Intermittent access total locomotion0.00.00.10.20.2-0.20.2-0.20.00.1-0.20.0-0.10.20.00.20.30.20.1-0.00.0-0.3-0.0
Intermittent access standard deviation0.00.20.3-0.5-0.40.4-0.40.4-0.40.5-0.60.3-0.40.5-0.40.50.50.50.4-0.40.4-0.40.4
Left kidney weight0.86.27.61.92.2-2.22.2-2.22.3-2.62.3-2.72.7-2.62.4-2.7-2.7-2.7-2.62.5-2.52.8-2.4
Right kidney weight0.96.47.81.92.4-2.42.4-2.42.4-2.62.4-2.82.7-2.62.4-2.7-2.8-2.7-2.62.5-2.52.8-2.4
Cocaine induced anxiety1.33.44.3-2.1-1.81.8-1.81.8-2.02.0-1.92.0-2.01.9-1.71.81.81.81.7-1.71.7-2.01.6
Post-drug Anxiety0.50.60.8-0.9-0.90.9-0.90.9-0.90.7-0.80.9-0.80.7-0.60.70.70.70.6-0.60.6-0.70.6
Baseline Anxiety1.11.83.21.81.2-1.21.2-1.21.5-1.51.4-1.41.6-1.41.3-1.3-1.2-1.2-1.21.2-1.21.4-1.2
Tail length0.00.10.30.5-0.10.1-0.10.1-0.0-0.10.0-0.30.20.1-0.20.20.20.20.3-0.30.3-0.30.3
Length with tail0.20.91.7-0.8-1.31.3-1.31.3-1.00.7-1.00.6-0.70.8-0.90.80.80.81.0-1.01.0-0.81.0
Length without tail0.42.02.5-1.4-1.61.6-1.61.6-1.41.3-1.51.4-1.41.3-1.41.31.31.31.3-1.41.3-1.31.4
Times rat made contact with spout1.51.82.2-1.0-1.31.3-1.31.3-1.11.2-1.11.3-1.31.4-1.41.41.41.41.5-1.51.5-1.41.5
Lifetime Intake2.12.66.52.61.8-1.81.8-1.81.8-1.91.8-1.81.7-1.41.5-1.3-1.3-1.3-1.31.3-1.30.9-1.3
Liver weight, left0.30.51.1-0.8-1.01.0-1.01.0-0.70.6-0.80.5-0.60.6-0.60.50.50.60.6-0.60.6-0.50.6
Liver weight, right0.51.01.2-0.7-1.11.1-1.11.1-0.80.8-0.90.9-1.10.9-1.00.90.91.01.0-1.01.0-1.01.0
Locomotor activity2.74.36.2-2.5-1.91.9-1.91.9-2.02.2-2.12.2-2.22.1-2.12.02.02.02.0-2.02.0-1.92.0
Locomotor testing distance1.53.64.3-2.0-1.61.6-1.61.6-1.92.1-1.82.0-2.02.0-1.91.91.91.91.9-1.91.9-1.91.9
Locomotor testing rearing0.10.41.4-1.2-0.50.5-0.50.5-0.80.9-0.80.7-0.60.7-0.70.60.60.60.6-0.60.6-0.40.6
Locomotion in novel chamber2.02.73.4-1.8-1.51.5-1.51.5-1.81.7-1.61.8-1.81.7-1.71.71.71.71.6-1.61.6-1.71.6
Locomotion in novel chamber post-restriction0.92.63.5-1.1-1.41.4-1.41.4-1.61.6-1.51.6-1.61.7-1.71.71.81.81.8-1.81.8-1.91.8
Fecal boli incidents, locomotor time 10.51.32.8-0.2-1.01.0-1.01.0-1.10.8-1.10.7-0.71.2-1.31.21.31.41.4-1.51.4-1.71.5
Change in fecal boli incidents, locomotor task0.60.61.00.60.7-0.70.7-0.70.9-0.60.8-0.60.6-0.80.8-0.8-0.8-0.8-0.80.8-0.81.0-0.8
Time >=10cm from walls, locomotor time 10.30.40.70.2-0.50.5-0.50.5-0.40.5-0.60.4-0.40.7-0.70.70.80.80.8-0.80.9-0.80.8
Bouts of movement, locomotor time 10.00.00.20.2-0.20.2-0.20.2-0.00.0-0.2-0.00.00.2-0.10.20.20.20.2-0.10.1-0.50.1
Total resting periods, locomotor time 10.00.00.30.50.1-0.10.1-0.10.3-0.20.1-0.30.3-0.10.2-0.1-0.0-0.1-0.10.1-0.1-0.2-0.2
Rest time, locomotor task time 10.20.30.80.90.5-0.50.5-0.50.4-0.50.6-0.70.7-0.50.6-0.4-0.4-0.4-0.50.6-0.60.4-0.6
Distance moved, locomotor task time 10.10.20.4-0.6-0.50.5-0.50.5-0.50.4-0.40.5-0.50.4-0.50.40.40.40.5-0.50.5-0.30.5
Vertical activity count, locomotor time 10.21.41.9-1.0-1.11.1-1.11.1-1.11.0-1.11.1-1.11.2-1.31.21.21.21.3-1.41.3-1.41.4
Time >=10cm from walls, locomotor time 20.10.40.80.80.6-0.60.6-0.60.9-0.50.7-0.50.5-0.60.7-0.7-0.6-0.6-0.60.6-0.60.7-0.6
Bouts of movement, locomotor time 20.30.91.01.01.0-1.01.0-1.01.0-1.00.9-1.01.0-1.01.0-1.0-1.0-1.0-1.01.0-1.00.9-1.0
Total resting periods, locomotor time 20.31.21.41.11.1-1.11.1-1.11.1-1.21.0-1.11.1-1.11.2-1.1-1.1-1.1-1.11.1-1.11.0-1.1
Rest time, locomotor task time 20.50.92.51.61.0-1.01.0-1.01.1-1.10.9-1.21.2-0.80.9-0.8-0.8-0.7-0.80.8-0.80.5-0.8
Distance moved, locomotor task time 20.71.03.0-1.7-1.01.0-1.01.0-1.01.2-1.01.3-1.30.8-0.90.80.80.70.7-0.70.7-0.40.7
Vertical activity count, locomotor time 20.71.72.8-1.7-1.41.4-1.41.4-1.31.5-1.31.5-1.51.2-1.31.21.21.21.2-1.21.2-1.01.2
Light reinforcement 11.46.28.2-2.9-2.42.4-2.42.4-2.52.6-2.52.7-2.62.4-2.52.42.42.42.4-2.52.5-2.42.5
Light reinforcement 21.73.94.8-2.2-1.91.9-1.91.9-1.82.0-2.21.8-1.92.0-2.02.02.02.02.0-2.02.0-1.92.0
Bone: marrow area0.00.10.2-0.1-0.10.1-0.10.1-0.10.2-0.40.2-0.20.3-0.40.40.40.40.4-0.40.5-0.30.5
Bone: maximum diameter0.40.71.1-0.9-0.40.4-0.40.4-0.71.0-0.71.0-1.00.9-1.00.90.90.91.0-1.01.0-0.91.0
Bone: maximum force0.20.40.60.40.6-0.60.6-0.60.6-0.60.5-0.50.5-0.60.6-0.7-0.7-0.7-0.70.6-0.70.7-0.6
Bone: maximum moment0.00.00.10.00.1-0.10.1-0.10.1-0.20.1-0.10.1-0.20.2-0.3-0.3-0.3-0.30.3-0.30.3-0.3
Mean time between licks in bursts0.00.00.1-0.3-0.20.2-0.20.2-0.10.1-0.2-0.10.20.1-0.20.20.10.10.1-0.20.1-0.10.1
Mean num. licks in bursts0.00.00.10.30.1-0.10.1-0.10.1-0.10.1-0.00.00.0-0.00.00.00.10.1-0.10.1-0.20.2
Cd content in liver0.10.10.2-0.10.3-0.30.3-0.30.2-0.20.1-0.30.4-0.30.3-0.3-0.3-0.4-0.40.4-0.40.4-0.4
Co content in liver0.00.00.10.30.3-0.30.3-0.30.3-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.10.1-0.10.2-0.1
Cu content in liver0.70.91.51.20.7-0.70.7-0.71.0-1.01.1-1.01.0-1.01.0-1.0-1.0-1.0-0.90.9-0.90.9-0.9
Fe content in liver2.12.63.3-1.4-1.71.7-1.71.7-1.51.6-1.41.7-1.71.6-1.51.51.61.61.6-1.61.6-1.81.6
K content in liver0.20.20.40.60.6-0.60.6-0.60.5-0.40.5-0.40.4-0.40.4-0.3-0.3-0.3-0.30.3-0.30.4-0.3
Mg content in liver0.40.40.5-0.3-0.60.6-0.60.6-0.50.6-0.50.7-0.70.6-0.60.70.70.70.7-0.70.7-0.70.7
Mn content in liver0.60.60.8-0.8-0.90.9-0.90.9-0.90.7-0.90.8-0.70.8-0.80.80.80.80.7-0.70.8-0.70.7
Na content in liver0.00.00.10.3-0.00.0-0.00.00.1-0.00.3-0.0-0.0-0.10.1-0.0-0.0-0.0-0.10.1-0.10.0-0.1
Rb content in liver0.20.20.60.80.3-0.30.3-0.30.5-0.60.5-0.60.6-0.50.6-0.5-0.5-0.5-0.50.5-0.50.4-0.5
Se content in liver0.00.00.10.10.1-0.10.1-0.10.2-0.30.1-0.20.2-0.20.1-0.2-0.2-0.2-0.20.1-0.20.2-0.1
Sr content in liver1.31.11.4-1.1-1.21.2-1.21.2-1.11.0-1.01.0-1.01.0-1.11.01.01.01.0-1.11.0-0.91.1
Zn content in liver1.82.13.01.51.7-1.71.7-1.71.6-1.41.6-1.41.4-1.41.3-1.4-1.4-1.3-1.31.3-1.31.4-1.2
Bone: minimum diameter0.10.20.3-0.5-0.20.2-0.20.2-0.50.5-0.40.6-0.60.5-0.50.50.50.50.5-0.50.5-0.50.5
Time in familiar zone, hab. session 10.20.20.7-0.6-0.60.6-0.60.6-0.60.2-0.80.2-0.20.5-0.40.50.50.40.4-0.40.4-0.40.4
Time in novel zone, hab. session 10.20.20.50.60.5-0.50.5-0.50.5-0.20.7-0.10.2-0.40.5-0.5-0.5-0.4-0.40.4-0.40.4-0.4
Total zone transitions, hab. session 10.81.11.5-0.9-1.01.0-1.01.0-1.01.2-0.91.1-1.21.1-1.11.11.11.11.1-1.11.1-1.11.1
Total locomotion distance, hab. session 11.11.62.3-1.2-1.11.1-1.11.1-1.11.3-1.01.4-1.51.3-1.31.31.31.31.3-1.31.3-1.31.3
Locomotion velocity, hab. session 11.41.92.8-1.3-1.21.2-1.21.2-1.31.5-1.01.5-1.71.4-1.51.41.41.51.5-1.51.5-1.51.5
Time in familiar zone, hab. session 20.70.81.1-1.0-1.01.0-1.01.0-1.00.9-0.80.9-0.70.9-0.80.90.90.80.8-0.70.7-0.90.7
Time in novel zone, hab. session 24.14.55.12.32.1-2.12.1-2.12.2-2.12.1-2.12.0-2.22.1-2.2-2.2-2.1-2.12.1-2.12.1-2.1
Total zone transitions, hab. session 22.02.63.2-1.5-1.41.4-1.41.4-1.61.8-1.11.7-1.81.7-1.71.61.61.71.7-1.71.7-1.81.7
Total locomotion distance, hab. session 21.21.51.9-1.1-1.01.0-1.01.0-1.21.3-0.71.3-1.41.3-1.31.31.31.31.4-1.41.4-1.41.4
Locomotion velocity, hab. session 21.11.51.9-1.1-1.01.0-1.01.0-1.21.3-0.71.2-1.41.3-1.31.21.21.31.4-1.41.4-1.41.4
Novel to familiar place preference ratio1.82.32.91.31.3-1.31.3-1.31.6-1.61.1-1.51.5-1.61.6-1.6-1.6-1.6-1.71.7-1.71.7-1.7
Novelty place preference2.93.74.51.61.7-1.71.7-1.72.0-2.01.6-1.81.8-2.02.0-2.0-2.0-2.0-2.12.1-2.12.0-2.1
Time in novel zone, NPP test2.83.44.21.61.6-1.61.6-1.61.9-1.91.5-1.81.8-1.92.0-1.9-1.9-1.9-2.02.0-2.01.9-2.0
Total zone transitions, NPP test1.82.63.0-1.5-1.51.5-1.51.5-1.61.7-1.31.7-1.71.7-1.71.61.61.71.7-1.71.7-1.71.7
Total locomotion distance, NPP test1.01.41.8-1.1-1.01.0-1.01.0-1.01.2-0.91.2-1.31.2-1.31.11.21.21.3-1.31.3-1.31.3
Locomotion velocity, NPP test0.91.21.6-1.0-0.90.9-0.90.9-1.01.2-0.81.2-1.21.1-1.21.11.11.11.2-1.31.2-1.31.3
Intraocular pressure0.40.61.00.30.8-0.80.8-0.80.6-0.60.7-0.70.8-0.80.7-0.9-0.9-0.9-0.80.8-0.81.0-0.8
Delta distance traveled before/after self-admin0.50.50.91.00.6-0.60.6-0.60.6-0.80.8-0.80.7-0.70.8-0.7-0.7-0.7-0.70.7-0.70.7-0.8
Delta ambulatory time before/after self-admin0.61.12.61.61.1-1.11.1-1.11.0-1.11.2-1.01.0-1.01.1-0.9-0.9-0.9-0.90.9-0.90.8-0.9
Parametrial fat weight7.217.120.2-4.0-4.54.5-4.54.5-4.23.7-4.23.8-3.94.1-4.04.14.14.14.0-4.04.0-4.14.0
Pavlov. Cond. lever latency0.00.10.2-0.0-0.30.3-0.30.3-0.20.1-0.50.1-0.00.2-0.10.30.30.20.2-0.20.2-0.20.1
Pavlov. Cond. magazine entry latency0.50.61.60.91.0-1.01.0-1.00.8-0.61.3-0.60.6-0.70.6-0.8-0.8-0.7-0.60.6-0.60.7-0.5
Pavlov. Cond. change in total contacts0.80.81.00.70.9-0.90.9-0.90.8-0.91.0-1.00.9-0.90.9-1.0-1.0-1.0-0.90.9-0.91.0-0.9
Pavlov. Cond. index score0.30.41.20.50.8-0.80.8-0.80.6-0.41.1-0.50.4-0.60.5-0.7-0.7-0.6-0.50.5-0.50.6-0.4
Pavlov. Cond. latency score0.20.31.00.50.8-0.80.8-0.80.5-0.31.0-0.30.3-0.50.4-0.6-0.6-0.5-0.40.4-0.40.5-0.4
Pavlov. Cond. lever contacts0.50.61.10.60.9-0.90.9-0.90.8-0.61.0-0.70.6-0.70.7-0.8-0.8-0.8-0.70.7-0.70.8-0.7
Pavlov. Cond. magazine entry number0.60.71.4-1.0-1.01.0-1.01.0-0.90.8-1.20.7-0.60.8-0.70.80.80.80.7-0.60.6-0.80.6
Pavlov. Cond. intertrial magazine entries0.20.20.3-0.3-0.50.5-0.50.5-0.40.4-0.50.4-0.50.5-0.50.50.50.50.5-0.50.5-0.40.5
Pavlov. Cond. lever-magazine prob. diff.0.40.41.10.60.8-0.80.8-0.80.7-0.51.1-0.50.4-0.60.5-0.7-0.7-0.6-0.50.5-0.50.7-0.5
Pavlov. Cond. response bias0.30.30.90.60.7-0.70.7-0.70.6-0.40.9-0.40.3-0.50.4-0.6-0.6-0.5-0.40.4-0.40.5-0.4
Pavlov. Cond. lever latency1.21.82.3-1.2-1.51.5-1.51.5-1.41.3-1.21.4-1.31.3-1.21.31.31.31.2-1.21.2-1.21.1
Pavlov. Cond. magazine entry latency3.24.55.91.92.4-2.42.4-2.42.3-1.92.1-2.02.0-2.02.0-2.1-2.1-2.1-2.02.0-2.02.1-2.0
Pavlov. Cond. change in total contacts1.12.63.01.31.7-1.71.7-1.71.6-1.61.5-1.71.7-1.61.5-1.7-1.7-1.7-1.61.5-1.61.6-1.5
Pavlov. Cond. index score3.04.75.92.02.4-2.42.4-2.42.3-2.02.1-2.12.1-2.12.0-2.2-2.2-2.1-2.02.0-2.02.1-2.0
Pavlov. Cond. latency score2.94.75.92.02.4-2.42.4-2.42.3-2.12.1-2.12.1-2.12.0-2.2-2.2-2.1-2.12.0-2.12.1-2.0
Pavlov. Cond. lever contacts1.52.22.81.41.7-1.71.7-1.71.6-1.51.4-1.51.5-1.41.3-1.5-1.5-1.4-1.31.3-1.31.3-1.2
Pavlov. Cond. magazine entry number5.47.18.5-2.3-2.92.9-2.92.9-2.82.5-2.62.6-2.62.6-2.52.72.72.62.6-2.62.6-2.72.5
Pavlov. Cond. intertrial magazine entries3.16.77.7-2.5-2.22.2-2.22.2-2.72.6-2.52.8-2.72.7-2.72.72.72.72.7-2.72.7-2.72.8
Pavlov. Cond. lever-magazine prob. diff.3.55.36.92.22.6-2.62.6-2.62.5-2.22.2-2.32.2-2.22.1-2.3-2.3-2.2-2.22.1-2.22.2-2.1
Pavlov. Cond. response bias3.04.15.41.82.3-2.32.3-2.32.2-1.92.0-2.01.9-2.01.9-2.0-2.1-2.0-1.91.9-1.91.9-1.8
Time in closed arm before self-admin2.13.64.0-2.0-1.81.8-1.81.8-1.92.0-2.01.8-1.82.0-2.02.02.02.02.0-2.01.9-2.01.9
Time in closed arm after self-admin3.03.44.4-2.1-1.91.9-1.91.9-2.01.9-1.91.9-1.91.8-1.81.81.81.81.7-1.71.7-1.61.7
Time in open arm before self-admin1.21.52.01.31.3-1.31.3-1.31.4-1.41.3-1.11.1-1.31.1-1.3-1.3-1.2-1.11.1-1.11.1-1.0
Time in open arm after self-admin0.60.61.10.40.7-0.70.7-0.70.9-0.70.7-0.50.6-0.80.8-0.9-0.9-0.9-0.90.9-0.91.1-0.8
Bone: periosteal estimation0.20.50.7-0.8-0.50.5-0.50.5-0.60.7-0.80.8-0.80.8-0.80.70.70.80.8-0.80.8-0.70.8
Bone: periosteal perimeter0.71.31.6-1.2-0.90.9-0.90.9-1.01.2-1.01.3-1.31.2-1.21.11.11.21.2-1.21.2-1.21.3
Bone: post-yield work0.50.91.4-1.0-1.21.2-1.21.2-1.10.9-0.91.0-1.00.8-0.80.90.90.80.8-0.70.8-0.70.7
Progressive ratio test 1 active lever presses2.23.97.42.72.3-2.32.3-2.32.2-2.22.2-2.01.9-1.81.8-1.7-1.7-1.7-1.61.6-1.61.3-1.6
Progressive ratio test 1 breakpoint2.03.46.62.62.2-2.22.2-2.22.1-2.12.0-1.91.7-1.71.7-1.6-1.6-1.6-1.51.5-1.51.3-1.5
Progressive ratio test 1 inactive lever presses0.10.20.80.90.7-0.70.7-0.70.5-0.60.4-0.30.2-0.30.4-0.2-0.2-0.2-0.20.2-0.20.0-0.2
Progressive ratio test 2 active lever presses2.23.28.72.92.1-2.12.1-2.12.0-2.11.9-1.91.8-1.51.6-1.4-1.3-1.3-1.31.3-1.20.9-1.3
Progressive ratio test 2 breakpoint2.63.38.72.92.2-2.22.2-2.22.0-2.22.0-1.91.9-1.51.6-1.4-1.4-1.3-1.31.3-1.30.9-1.3
Progressive ratio test 2 inactive lever presses0.10.20.50.70.6-0.60.6-0.60.5-0.70.4-0.30.3-0.40.5-0.3-0.3-0.4-0.40.5-0.40.2-0.5
Incentive Sensitization - Responses0.51.34.72.21.4-1.41.4-1.41.3-1.41.2-1.21.2-0.80.9-0.8-0.7-0.7-0.60.7-0.70.3-0.7
Incentive Sensitization - Breakpoint0.71.55.42.31.5-1.51.5-1.51.4-1.51.3-1.31.3-0.91.0-0.9-0.8-0.7-0.70.8-0.70.4-0.8
Sum of active levers in priming session hrs 5-60.30.30.50.10.6-0.60.6-0.60.6-0.40.5-0.20.2-0.60.6-0.6-0.6-0.6-0.70.7-0.70.7-0.7
Progressive ratio0.10.22.2-1.5-0.20.2-0.20.2-0.40.4-0.30.6-0.60.0-0.1-0.1-0.2-0.2-0.20.1-0.20.5-0.1
Food seeking constrained by brief footshock1.31.62.21.01.1-1.11.1-1.11.0-1.31.2-1.21.2-1.31.3-1.4-1.4-1.4-1.31.3-1.31.5-1.3
Seeking ratio, punishment vs. effort0.40.92.71.60.8-0.80.8-0.80.9-1.11.0-1.31.3-0.90.9-0.8-0.8-0.8-0.80.8-0.70.7-0.8
Retroperitoneal fat weight6.328.331.4-5.5-5.35.3-5.35.3-5.45.2-5.65.1-5.35.3-5.35.45.45.35.3-5.25.2-5.25.2
Reaction time number correct0.62.23.21.81.7-1.71.7-1.71.7-1.51.5-1.41.3-1.41.4-1.4-1.4-1.3-1.31.3-1.31.3-1.3
Reaction time mean minus median0.21.52.60.41.3-1.31.3-1.31.1-0.81.0-1.01.0-1.21.2-1.3-1.3-1.4-1.31.3-1.41.6-1.3
Reaction time mean minus median AUC0.21.12.10.21.1-1.11.1-1.10.9-0.70.9-0.80.8-1.11.0-1.2-1.2-1.2-1.21.2-1.21.5-1.1
Reaction time num false alarms0.10.10.20.40.2-0.20.2-0.20.4-0.50.4-0.20.3-0.40.5-0.3-0.4-0.4-0.40.4-0.40.3-0.4
Reaction time num false alarms AUC0.00.00.10.2-0.10.1-0.10.10.0-0.10.00.2-0.10.1-0.00.10.10.10.1-0.10.1-0.20.1
Reaction time trials correct on left0.62.23.21.81.7-1.71.7-1.71.7-1.51.5-1.41.3-1.41.4-1.4-1.4-1.3-1.31.3-1.31.3-1.3
Reaction time trials on left0.72.33.41.91.8-1.81.8-1.81.8-1.61.5-1.41.3-1.41.4-1.4-1.4-1.3-1.31.3-1.31.3-1.3
Reaction time mean0.10.21.4-1.2-0.00.0-0.00.0-0.10.3-0.10.0-0.0-0.30.2-0.4-0.5-0.5-0.60.5-0.60.8-0.5
Reaction time mean AUC0.20.41.2-0.80.2-0.20.2-0.20.10.00.1-0.30.2-0.60.5-0.7-0.7-0.8-0.80.8-0.91.1-0.8
Median of all reaction times0.20.22.3-1.5-0.50.5-0.50.5-0.60.6-0.50.4-0.40.1-0.1-0.0-0.1-0.2-0.20.2-0.20.4-0.2
Reaction time omissions0.10.10.40.00.1-0.10.1-0.1-0.00.3-0.10.3-0.40.4-0.50.40.40.40.6-0.60.6-0.50.6
Reaction time false alarm rate0.40.60.8-0.6-0.90.9-0.90.9-0.80.6-0.70.8-0.70.7-0.70.70.70.70.7-0.70.7-0.80.7
Reaction time premature initiation rate1.01.62.11.01.1-1.11.1-1.11.2-1.31.2-1.21.2-1.31.2-1.4-1.4-1.3-1.31.3-1.31.5-1.2
Reaction time premature initiations1.44.14.52.02.0-2.02.0-2.02.1-2.12.0-2.01.9-2.02.0-2.1-2.1-2.0-2.02.0-2.02.1-1.9
Std. dev. reaction times0.10.41.1-0.40.7-0.70.7-0.70.4-0.20.3-0.40.4-0.60.6-0.7-0.8-0.8-0.80.8-0.81.1-0.8
Reaction time trials completed0.72.33.41.91.8-1.81.8-1.81.8-1.61.5-1.41.3-1.41.4-1.4-1.4-1.3-1.31.3-1.31.3-1.3
Reaction time trials AUC0.72.33.41.81.8-1.81.8-1.81.8-1.61.5-1.41.3-1.41.5-1.4-1.4-1.4-1.31.4-1.31.3-1.3
Run reversals in cocaine runway, females1.31.52.2-1.0-0.70.7-0.70.7-1.01.2-1.11.2-1.21.4-1.41.41.41.41.4-1.41.5-1.41.5
Run reversals in cocaine runway, males0.50.51.40.0-0.50.5-0.50.5-0.60.5-0.50.4-0.40.8-0.80.80.80.91.0-1.01.0-1.21.0
Latency to leave start box in cocaine runway0.20.30.50.20.2-0.20.2-0.20.3-0.40.3-0.50.5-0.60.6-0.6-0.6-0.6-0.70.7-0.70.6-0.7
Latency to leave start box in cocaine runway, F1.41.72.81.71.4-1.41.4-1.41.3-1.31.2-1.31.3-1.31.4-1.2-1.2-1.2-1.31.3-1.31.1-1.4
Latency to leave start box in cocaine runway, M1.61.54.8-2.2-1.71.7-1.71.7-1.51.3-1.31.1-1.10.9-1.00.80.70.70.7-0.80.7-0.40.8
Std. dev. time between licks in bursts1.52.83.5-1.8-1.61.6-1.61.6-1.51.9-1.61.8-1.81.7-1.81.71.61.71.7-1.71.7-1.61.7
Total sessions with >9 infusions1.62.05.02.21.7-1.71.7-1.71.5-1.61.7-1.51.4-1.21.2-1.2-1.1-1.1-1.01.0-1.00.6-1.0
Short access day 1 total inactive lever presses0.00.00.10.20.1-0.10.1-0.10.0-0.30.0-0.10.10.00.1-0.00.0-0.0-0.10.1-0.1-0.1-0.1
Short access day 10 total inactive lever presses0.00.20.3-0.5-0.30.3-0.30.3-0.40.4-0.50.4-0.30.5-0.50.50.50.50.5-0.50.5-0.30.5
Short access day 1 total infusions0.30.63.21.80.8-0.80.8-0.80.8-1.20.9-0.90.8-0.50.6-0.4-0.4-0.3-0.30.4-0.3-0.1-0.4
Short access day 10 total infusions0.30.52.61.60.8-0.80.8-0.80.8-0.80.9-1.00.9-0.50.6-0.5-0.4-0.4-0.40.5-0.40.0-0.5
Short access total infusions1.72.47.02.61.6-1.61.6-1.61.7-1.91.8-1.81.7-1.41.5-1.3-1.3-1.2-1.21.3-1.20.8-1.3
Short access day 1 locomotion0.20.31.51.20.8-0.80.8-0.80.7-0.70.7-0.50.4-0.40.4-0.3-0.3-0.2-0.20.2-0.2-0.1-0.2
Short access day 10 total locomotion0.62.42.9-1.7-1.51.5-1.51.5-1.61.6-1.61.5-1.71.6-1.51.61.61.61.5-1.41.4-1.41.4
Short access total locomotion0.20.30.5-0.4-0.60.6-0.60.6-0.60.4-0.50.5-0.60.5-0.40.60.60.60.5-0.50.5-0.70.4
One hour access (0.3 mA shock)1.51.84.82.21.7-1.71.7-1.71.4-1.51.4-1.51.5-1.11.1-1.0-0.9-0.9-0.90.9-0.90.6-1.0
Compulsive drug intake0.10.20.5-0.7-0.40.4-0.40.4-0.50.4-0.40.4-0.30.4-0.50.30.30.40.4-0.40.4-0.20.4
One hour access (shock baseline)0.71.96.12.51.7-1.71.7-1.71.5-1.51.5-1.61.5-1.11.3-1.0-1.0-1.0-1.01.1-1.00.5-1.1
Social response proportion0.60.82.31.50.9-0.90.9-0.91.0-1.01.1-1.21.2-0.80.8-0.7-0.7-0.7-0.70.7-0.70.6-0.7
Social responses0.00.00.20.40.2-0.20.2-0.20.3-0.10.4-0.20.2-0.0-0.00.00.00.10.1-0.10.10.00.1
Social time0.10.10.30.60.4-0.40.4-0.40.3-0.30.3-0.50.4-0.10.1-0.0-0.0-0.00.00.0-0.00.1-0.1
Soleus weight0.20.71.2-1.1-0.90.9-0.90.9-0.80.7-1.00.8-0.80.8-0.80.70.70.70.7-0.80.7-0.50.8
Bone: stiffness2.74.95.81.92.3-2.32.3-2.32.1-2.22.1-2.22.2-2.22.1-2.3-2.3-2.3-2.22.2-2.22.4-2.1
Tibialis anterior weight0.10.50.80.70.7-0.70.7-0.70.7-0.70.9-0.60.6-0.70.6-0.8-0.8-0.8-0.60.6-0.60.8-0.6
Time to tail flick, vehicle, before self-admin0.50.61.91.40.9-0.90.9-0.90.8-0.90.9-0.90.7-0.70.7-0.6-0.6-0.6-0.60.6-0.60.4-0.6
Time to tail flick, vehicle, after self-admin0.40.92.0-0.2-0.60.6-0.60.6-0.90.9-0.80.8-0.91.1-1.01.11.21.21.2-1.11.1-1.41.1
Time to tail flick, test, before self-admin3.03.44.3-1.2-2.02.0-2.02.0-2.01.6-1.81.3-1.41.9-1.91.91.91.92.0-2.02.0-2.11.9
Time to tail flick, test, after self-admin0.10.10.20.3-0.20.2-0.20.2-0.10.0-0.20.1-0.10.4-0.30.40.40.40.5-0.50.5-0.50.5
Delta time to tail flick, vehicle, before/after SA0.70.81.5-0.3-0.50.5-0.50.5-0.80.9-0.80.8-0.81.0-0.91.01.11.11.1-1.11.1-1.21.0
Delta time to tail flick, test, before/after SA0.91.21.71.11.2-1.21.2-1.21.3-1.11.1-1.01.0-1.01.0-1.0-1.0-1.0-1.00.9-0.91.0-0.9
Tibia length0.00.10.10.20.4-0.40.4-0.40.1-0.30.2-0.30.2-0.20.2-0.2-0.2-0.2-0.20.1-0.20.0-0.1
Ambulatory time before self-admin0.62.07.0-2.6-1.51.5-1.51.5-1.31.5-1.71.5-1.31.2-1.41.11.11.01.1-1.11.1-0.81.2
Ambulatory time after self-admin0.30.51.4-1.2-0.80.8-0.80.8-0.50.6-0.80.8-0.70.6-0.70.60.60.60.5-0.60.6-0.60.6
Bone: tissue strength0.30.30.50.60.1-0.10.1-0.10.6-0.60.3-0.70.7-0.60.7-0.5-0.5-0.5-0.70.7-0.60.6-0.7
Total heroin consumption1.11.31.91.20.9-0.90.9-0.91.4-1.21.2-1.01.1-1.21.2-1.2-1.2-1.2-1.21.2-1.21.2-1.3
Bone: trabecular number0.30.51.1-1.0-0.70.7-0.70.7-0.70.8-0.90.7-0.70.7-0.70.60.60.60.6-0.60.6-0.60.6
Bone: trabecular spacing0.10.10.10.0-0.30.3-0.30.3-0.30.0-0.10.2-0.20.3-0.30.30.30.30.4-0.40.4-0.30.4
Bone: trabecular thickness0.40.60.70.50.8-0.80.8-0.80.7-0.70.5-0.80.8-0.80.7-0.8-0.8-0.8-0.80.8-0.80.8-0.8
Bone: trabecular tissue density0.61.01.11.00.9-0.90.9-0.90.9-1.00.8-1.01.0-1.01.0-1.0-1.0-1.0-1.11.1-1.11.0-1.1
Water consumed over 24 hours0.20.40.7-0.5-0.60.6-0.60.6-0.50.6-0.60.5-0.50.7-0.70.70.70.70.8-0.80.8-0.60.8
Number of responses in last shaping day0.50.61.2-0.10.7-0.70.7-0.70.7-0.50.7-0.60.4-0.90.8-0.9-1.0-1.0-1.00.9-0.91.1-0.9