Hub : Genes

Zdhhc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Zdhhc1 0.3 0.16 2.4e-03 0 0.01 0.01 -0 2.1e-01 1.6e-02 5.6e-02 6.9e-01
2 pVTA gene expression Zdhhc1 0.16 0.12 4.9e-03 0.03 0.03 -0 0.02 2.6e-02 1.6e-02 3.9e-01 3.6e-02
3 RMTg isoform ratio XM_039097614.1 0.15 0.11 4.5e-04 0.06 0.12 0.13 0.11 1.2e-02 4.4e-04 2.4e-04 7.9e-04
4 RMTg alternative TSS XM_039097614.1 0.09 0.08 8.1e-03 0.04 0.08 0.09 0.07 2.6e-02 4.5e-03 2.3e-03 7.4e-03
5 Liver mRNA stability Zdhhc1 0.03 0.03 3.0e-03 0.01 0.01 0.01 0.01 9.9e-03 2.0e-02 1.3e-02 2.3e-02
6 Adipose isoform ratio XM_008772485.3 0.02 0.02 5.6e-03 0.01 0.01 0 0.01 2.2e-02 3.1e-02 1.9e-01 4.0e-02
7 Adipose alternative TSS XM_039097615.1 0.09 0.08 4.9e-10 0.07 0.07 0.07 0.07 1.2e-08 2.2e-08 1.4e-08 1.3e-08
8 Adipose alternative TSS XM_017601228.2 0.08 0.06 5.1e-10 0.06 0.07 0.07 0.07 1.8e-07 1.8e-08 6.6e-08 7.1e-08
9 Adipose alternative TSS XM_017601228.2 0.06 0.05 1.3e-07 0.05 0.05 0.05 0.05 4.0e-06 1.7e-06 4.1e-06 4.7e-06
10 BLA mRNA stability Zdhhc1 0.06 0.05 3.8e-04 0.05 0.07 0.06 0.06 8.4e-04 1.8e-04 5.7e-04 3.4e-04
11 Adipose isoform ratio XM_039097615.1 0.09 0.07 7.7e-11 0.08 0.08 0.08 0.08 5.4e-09 2.5e-09 5.1e-09 6.0e-09
12 Adipose alternative TSS NM_001039099.1 0.07 0.05 1.8e-09 0.06 0.07 0.06 0.06 3.2e-07 6.6e-08 1.6e-07 1.6e-07
13 Adipose isoform ratio XM_017601227.2 0.04 0.03 1.3e-05 0.04 0.04 0.03 0.04 7.2e-05 5.2e-05 1.1e-04 7.5e-05
14 NAcc alternative TSS NM_001039099.1 0.02 0.02 6.0e-03 0.01 0.01 0.01 0.01 2.6e-02 1.3e-02 6.7e-02 4.3e-02
15 Adipose alternative TSS XM_017601226.2 0.02 0.02 4.8e-03 0.02 0.02 0.02 0.02 3.3e-03 6.5e-03 4.7e-03 5.8e-03
16 Adipose alternative TSS XM_017601226.2 0.03 0.03 5.6e-04 0.03 0.02 0.03 0.02 6.0e-04 1.1e-03 7.6e-04 8.6e-04
17 Liver gene expression Zdhhc1 0.13 0.09 1.4e-14 0.1 0.11 0.1 0.1 2.0e-11 9.5e-12 8.2e-11 4.0e-11
18 BLA gene expression Zdhhc1 0.06 0.06 7.4e-03 0.04 0.03 0.02 0.03 5.4e-03 8.2e-03 1.8e-02 9.3e-03
19 Adipose gene expression Zdhhc1 0.21 0.12 0.0e+00 0.15 0.14 0.14 0.15 5.4e-16 9.1e-16 3.1e-15 6.5e-16
20 Adipose mRNA stability Zdhhc1 0.07 0.08 2.0e-04 0.02 0.02 0.04 0.02 1.6e-03 1.6e-03 2.2e-05 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.20.32.11.5-0.7-0.3-0.2-0.6-0.40.50.40.40.4-0.5-0.40.4-0.4-0.4-0.40.4-0.50.10.5
Area under the delay curve0.10.11.0-1.00.3-0.10.20.30.2-0.3-0.2-0.2-0.10.20.1-0.10.10.10.1-0.20.20.1-0.3
BMI with tail0.10.41.3-1.10.60.80.90.60.5-0.4-0.7-0.7-0.60.60.7-0.60.70.30.3-0.70.6-0.4-0.4
BMI without tail1.43.03.7-1.91.91.81.71.71.8-1.8-1.7-1.7-1.71.71.7-1.71.71.71.7-1.71.9-1.4-1.5
Body weight0.10.51.21.1-0.7-0.9-0.7-0.8-0.60.60.80.80.7-0.7-0.70.7-0.7-0.4-0.40.8-0.70.70.8
Weight adjusted by age0.10.10.6-0.80.1-0.3-0.7-0.1-0.10.30.20.20.2-0.2-0.20.2-0.2-0.1-0.10.2-0.00.50.3
Bone surface1.52.76.92.6-1.9-1.7-1.8-1.8-1.61.31.61.61.6-1.6-1.61.6-1.6-1.2-1.21.6-1.71.41.6
Bone volume1.32.37.02.6-1.8-1.5-1.4-1.7-1.41.31.51.51.4-1.5-1.51.5-1.4-1.1-1.11.4-1.51.11.4
Breakpoint value in progressive ratio session3.33.65.2-0.91.72.32.31.91.8-1.6-2.0-2.0-2.01.92.0-2.02.01.81.8-2.01.7-2.3-1.7
Number of licking bursts0.81.01.21.1-1.1-1.0-0.9-1.0-1.00.91.01.01.0-1.0-1.01.0-1.0-0.9-0.91.0-1.10.90.9
Context. condit. distance diff. score0.20.22.91.7-0.1-0.1-0.4-0.0-0.1-0.4-0.0-0.0-0.10.10.0-0.10.10.60.6-0.0-0.00.10.0
Locomotion velocity, session 10.10.10.70.8-0.4-0.3-0.2-0.4-0.20.40.20.20.3-0.2-0.20.2-0.2-0.4-0.40.1-0.10.10.3
Locomotion distance, session 10.10.10.3-0.00.40.40.40.50.4-0.2-0.4-0.4-0.40.40.4-0.40.40.20.2-0.40.6-0.5-0.2
Locomotion velocity, session 20.50.61.0-0.80.90.90.30.80.7-0.9-0.7-0.7-0.80.70.7-0.80.71.01.0-0.60.7-0.4-0.5
Locomotion distance, session 20.10.20.3-0.10.50.40.50.60.4-0.5-0.4-0.4-0.50.50.4-0.50.40.50.5-0.40.6-0.5-0.4
Locomotion velocity, session 30.20.20.80.20.30.50.90.40.6-0.2-0.6-0.5-0.50.50.5-0.50.60.20.2-0.60.4-0.6-0.3
Locomotion distance, session 30.10.10.40.50.30.00.10.30.3-0.5-0.2-0.2-0.30.30.2-0.30.20.60.6-0.20.30.0-0.2
Stereotopy head waving bouts, day 30.20.21.7-1.3-0.1-0.2-0.0-0.2-0.30.70.30.30.4-0.4-0.30.4-0.3-0.7-0.70.3-0.50.30.4
Stereotopy head waving duration, day 30.50.51.2-0.2-0.7-0.6-0.5-0.7-0.90.80.70.70.7-0.8-0.70.8-0.8-0.8-0.80.8-1.10.50.7
Locomotion velocity, session 70.10.12.01.4-0.30.30.2-0.10.0-0.1-0.1-0.1-0.10.10.1-0.10.10.20.2-0.2-0.0-0.3-0.1
Locomotion distance, session 70.10.10.80.9-0.00.20.30.20.1-0.3-0.2-0.2-0.20.20.2-0.20.20.50.5-0.2-0.0-0.2-0.2
Stereotopy head waving bouts, day 70.40.41.11.0-0.9-0.4-0.3-0.7-0.60.70.60.60.6-0.6-0.60.6-0.6-0.7-0.70.6-0.90.30.6
Stereotopy head waving duration, day 70.50.71.10.6-1.0-0.7-0.3-0.9-0.81.00.70.70.8-0.8-0.70.8-0.7-1.1-1.10.7-1.00.50.8
Locomotion velocity, session 80.30.34.52.1-0.30.30.4-0.10.3-0.1-0.3-0.3-0.20.20.3-0.20.30.20.2-0.40.4-0.7-0.3
Locomotion distance, session 80.30.51.81.30.30.40.50.60.5-0.7-0.6-0.6-0.60.60.6-0.70.60.90.9-0.60.6-0.5-0.5
Degree of sensitization distance0.00.00.10.2-0.2-0.1-0.2-0.2-0.30.20.20.20.2-0.2-0.20.2-0.2-0.2-0.20.2-0.30.20.2
Degree of sensitization stereotypy0.30.30.60.8-0.7-0.4-0.1-0.6-0.50.60.50.50.5-0.5-0.50.5-0.5-0.6-0.60.4-0.70.30.5
Conditioned locomotion1.92.26.42.5-1.6-1.6-1.8-1.6-1.60.91.61.51.4-1.5-1.51.4-1.5-0.7-0.71.6-1.61.21.2
Cocaine response after cond. corrected0.50.62.0-0.6-0.7-0.6-0.1-0.6-0.51.20.40.50.7-0.5-0.50.7-0.5-1.4-1.40.4-0.50.70.8
Cocaine response after cond. not corrected0.20.31.8-1.3-0.1-0.00.2-0.10.00.8-0.1-0.00.20.0-0.00.2-0.0-1.0-1.0-0.1-0.00.50.3
Cocaine response before conditioning1.11.43.4-1.81.51.20.51.21.3-1.2-1.2-1.1-1.11.21.1-1.11.11.01.0-1.11.2-0.6-1.1
Saline control response3.64.87.1-0.4-2.0-2.3-1.7-2.1-2.52.12.32.32.3-2.3-2.32.3-2.3-2.3-2.32.3-2.72.01.8
Bone: connectivity density0.10.12.51.6-0.30.20.1-0.00.1-0.0-0.1-0.1-0.10.00.1-0.10.10.20.2-0.10.0-0.10.1
Bone: cortical apparent density1.21.63.8-0.30.91.42.01.11.3-0.6-1.4-1.4-1.21.31.4-1.31.40.70.7-1.41.3-1.7-1.0
Bone: cortical area0.60.91.91.4-1.0-1.0-1.1-1.0-0.70.90.90.90.9-0.9-0.90.9-0.9-0.7-0.70.9-0.80.71.0
Bone: cortical porosity0.20.31.2-0.40.60.2-0.20.40.4-1.1-0.2-0.2-0.40.30.2-0.30.21.01.0-0.10.3-0.1-0.7
Bone: cortical porosity0.20.31.1-0.30.60.2-0.10.40.5-1.0-0.3-0.3-0.40.40.3-0.40.30.90.9-0.20.4-0.3-0.7
Bone: cortical thickness0.20.20.60.8-0.6-0.4-0.3-0.5-0.40.70.40.40.5-0.5-0.40.5-0.4-0.6-0.60.4-0.40.20.6
Bone: cortical thickness0.20.32.11.5-0.1-0.3-0.90.0-0.3-0.60.40.30.1-0.3-0.30.1-0.30.80.80.4-0.30.40.0
Bone: cortical tissue density1.11.43.6-0.30.91.41.91.11.3-0.5-1.3-1.3-1.21.31.3-1.21.30.70.7-1.41.2-1.7-1.0
Condit. Reinf. active minus inactive responses3.54.05.6-1.72.02.12.42.12.0-1.9-2.1-2.1-2.02.12.1-2.02.11.71.7-2.12.0-1.8-1.9
Condit. Reinf. active-inactive response ratio3.43.64.8-1.51.91.92.22.01.9-2.0-2.0-1.9-1.92.01.9-1.91.91.81.8-2.01.9-1.6-2.0
Condit. Reinf. active responses2.53.03.6-1.61.81.81.91.81.7-1.7-1.8-1.8-1.81.81.8-1.81.81.61.6-1.81.8-1.5-1.6
Condit. Reinf. inactive responses0.10.20.40.30.40.40.10.40.4-0.4-0.4-0.4-0.50.40.4-0.40.40.60.6-0.40.5-0.5-0.2
Incentive salience index mean1.72.13.1-0.91.41.51.81.41.4-1.4-1.5-1.5-1.51.51.5-1.51.51.41.4-1.51.4-1.4-1.4
Condit. Reinf. lever presses0.10.10.20.30.00.40.40.00.0-0.4-0.2-0.2-0.20.20.2-0.20.20.40.4-0.20.0-0.3-0.4
Condit. Reinf. active minus inactive responses0.91.21.51.0-1.1-1.2-1.0-1.2-1.10.91.21.21.1-1.1-1.11.1-1.1-0.8-0.81.2-1.20.91.0
Condit. Reinf. active-inactive response ratio0.91.01.30.9-1.0-0.9-1.0-1.1-0.91.11.01.01.0-1.0-0.91.0-0.9-1.0-1.00.9-1.11.01.1
Condit. Reinf. active responses0.40.61.00.8-0.8-0.8-0.7-0.9-0.80.40.90.90.8-0.9-0.90.8-0.9-0.3-0.30.9-1.00.60.5
Condit. Reinf. inactive responses0.30.30.9-0.50.60.50.60.60.3-1.0-0.3-0.4-0.50.40.4-0.40.30.90.9-0.30.4-0.6-0.8
Condit. Reinf. lever presses2.33.26.20.21.62.01.41.61.6-2.3-1.6-1.7-1.91.61.7-1.81.72.52.5-1.61.5-1.8-1.9
Condit. Reinf. lever reinforcers received0.10.10.30.5-0.4-0.3-0.3-0.4-0.5-0.10.50.40.3-0.5-0.40.4-0.40.20.20.5-0.60.10.1
Conditioned reinforcement - actives0.90.91.5-1.01.20.70.51.11.0-1.2-0.9-0.9-1.01.00.9-1.00.91.11.1-0.91.1-0.4-1.1
Conditioned reinforcement - inactives0.10.11.81.4-0.2-0.10.2-0.10.20.0-0.2-0.2-0.10.30.2-0.20.3-0.2-0.2-0.30.2-0.4-0.3
Conditioned locomotion2.12.57.32.7-1.9-1.8-1.7-1.6-1.51.41.51.51.5-1.4-1.51.5-1.4-1.4-1.41.4-1.51.61.3
Patch foraging indifference point 0 sec3.45.47.51.5-2.3-2.7-2.6-2.4-2.52.02.42.42.4-2.4-2.42.4-2.4-2.1-2.12.4-2.32.42.1
Patch foraging indifference point AUC1.92.29.03.0-1.7-1.4-1.6-1.5-1.51.11.41.41.3-1.4-1.41.3-1.4-0.8-0.81.4-1.61.31.3
Delay disc. indifference point, 0s delay1.01.13.6-1.91.11.11.41.11.0-0.8-1.1-1.0-0.91.01.0-0.91.00.50.5-1.10.9-1.0-1.0
Delay disc. indifference point, 16s delay0.50.54.2-2.10.2-0.8-0.8-0.3-0.2-0.10.50.50.5-0.4-0.50.5-0.6-0.2-0.20.6-0.11.10.2
Delay disc. indifference point, 2s delay0.50.68.32.9-1.0-0.4-0.0-0.5-0.50.20.30.30.3-0.2-0.20.3-0.2-0.3-0.30.1-0.5-0.10.2
Delay disc. indifference point, 24s delay0.10.10.40.10.0-0.4-0.6-0.0-0.1-0.50.20.20.2-0.1-0.20.1-0.20.20.20.20.00.4-0.0
Delay disc. indifference point, 4s delay0.30.40.70.70.30.70.80.50.60.1-0.7-0.7-0.60.60.7-0.60.70.10.1-0.70.6-0.8-0.2
Delay disc. indifference point, 8s delay0.10.11.0-1.00.2-0.3-0.10.10.0-0.20.00.00.10.0-0.10.0-0.1-0.2-0.20.00.00.3-0.1
Indifference point function ln k0.20.30.6-0.30.50.40.80.50.5-0.4-0.6-0.6-0.50.70.6-0.60.60.20.2-0.70.7-0.6-0.6
Indifference point function log k0.20.30.6-0.30.50.40.80.50.5-0.4-0.6-0.6-0.50.70.6-0.60.60.20.2-0.70.7-0.6-0.6
Patch foraging total patch changes 0 sec3.35.37.21.4-2.2-2.7-2.7-2.3-2.42.02.42.42.4-2.4-2.42.4-2.4-2.0-2.02.4-2.32.42.1
Patch foraging total patch changes 12 sec2.63.35.12.3-1.9-2.1-2.1-1.9-1.81.41.91.91.8-1.8-1.91.8-1.9-1.3-1.31.9-1.71.81.7
Patch foraging total patch changes 18 sec3.03.86.92.3-1.9-2.3-2.6-1.9-2.11.12.12.11.9-2.0-2.11.9-2.1-1.0-1.02.2-2.02.11.7
Patch foraging total patch changes 24 sec0.50.68.32.9-0.8-0.5-1.0-0.5-0.50.30.50.40.3-0.4-0.40.4-0.40.00.00.4-0.30.20.6
Patch foraging total patch changes 6 sec2.33.46.22.5-2.0-2.0-1.8-1.8-1.91.71.81.81.8-1.8-1.81.8-1.8-1.6-1.61.8-1.81.51.7
Patch foraging time to switch 0 sec1.32.03.1-0.71.41.51.51.31.6-1.3-1.5-1.4-1.41.41.4-1.41.41.31.3-1.51.8-1.6-1.3
Patch foraging water rate 0 sec2.33.65.5-0.4-1.6-2.0-2.3-1.8-2.01.62.02.02.0-2.0-2.02.0-2.0-1.8-1.82.0-2.12.31.7
Patch foraging water rate 12 sec0.30.41.11.0-0.5-0.7-1.0-0.6-0.30.70.50.50.5-0.5-0.50.5-0.5-0.5-0.50.6-0.40.80.8
Patch foraging water rate 18 sec0.50.78.02.8-0.6-0.6-1.4-0.5-0.20.60.50.50.4-0.4-0.50.4-0.4-0.2-0.20.5-0.20.61.0
Patch foraging water rate 24 sec0.10.21.8-1.30.3-0.3-0.80.10.00.20.20.20.2-0.2-0.20.2-0.2-0.2-0.20.3-0.30.70.4
Patch foraging water rate 6 sec1.31.98.93.0-1.5-1.2-1.7-1.3-1.11.11.31.21.1-1.2-1.21.1-1.2-0.9-0.91.2-1.21.31.4
Seeking ratio, delayed vs. immediate footshock2.73.23.91.2-1.8-1.8-1.8-1.7-2.01.81.71.71.8-1.7-1.81.8-1.7-1.9-1.91.7-1.91.81.8
Distance traveled before self-admin3.63.853.67.3-2.4-0.7-0.8-1.4-1.31.10.90.90.9-1.0-0.80.8-0.7-0.7-0.70.7-1.40.31.4
Distance traveled after self-admin0.30.30.70.5-0.6-0.4-0.5-0.4-0.50.80.40.40.5-0.4-0.40.4-0.4-0.7-0.70.4-0.60.60.8
Extensor digitorum longus weight0.62.54.11.51.31.61.11.51.6-1.8-1.4-1.5-1.71.51.5-1.61.62.02.0-1.51.6-1.6-1.4
Bone: elastic displacement1.82.02.4-0.1-1.3-1.5-1.3-1.3-1.51.51.51.51.5-1.5-1.51.5-1.5-1.5-1.51.5-1.51.51.4
Bone: elastic work0.81.01.4-0.2-0.9-0.8-0.8-0.8-1.11.21.01.01.0-1.0-1.01.0-1.0-1.2-1.21.0-1.11.11.0
Bone: endosteal estimation0.00.10.3-0.3-0.0-0.5-0.2-0.0-0.20.30.30.30.2-0.2-0.30.2-0.3-0.3-0.30.3-0.20.30.4
Bone: endosteal perimeter0.40.83.21.8-0.8-1.2-1.5-0.9-0.70.30.90.90.8-0.8-0.90.8-0.9-0.0-0.01.0-0.70.90.8
Epididymis fat weight4.29.714.03.0-3.0-3.5-3.7-3.1-3.12.63.33.23.1-3.2-3.23.1-3.2-2.4-2.43.3-3.03.43.2
Delta time in closed arm before/after self-admin0.20.20.8-0.9-0.1-0.5-0.2-0.2-0.00.20.40.40.4-0.3-0.40.4-0.4-0.3-0.30.4-0.40.60.2
Delta time in open arm before/after self-admin0.80.812.63.5-0.70.40.7-0.1-0.20.5-0.3-0.3-0.30.20.3-0.30.4-0.1-0.1-0.4-0.3-1.10.2
Diff in mean of infusions in LGA sessions1.61.83.00.41.01.61.31.31.2-1.6-1.3-1.3-1.41.21.3-1.31.31.61.6-1.31.0-1.7-1.4
Delay discount exponential model param0.10.10.80.9-0.4-0.0-0.2-0.3-0.30.40.20.20.2-0.3-0.20.2-0.2-0.2-0.20.2-0.30.00.3
Extinction: sum of active levers before priming1.81.86.1-2.51.51.31.61.51.4-0.7-1.3-1.3-1.31.31.3-1.31.31.01.0-1.31.0-1.4-1.0
Active lever presses in extinction session 60.70.69.7-3.10.90.30.40.50.6-0.8-0.3-0.3-0.30.30.2-0.20.20.30.3-0.20.3-0.2-0.4
Bone: final force0.71.21.6-0.31.11.00.81.21.2-1.2-1.1-1.1-1.11.11.1-1.11.11.31.3-1.11.1-1.1-1.0
Bone: final moment0.30.40.7-0.30.70.60.50.80.7-0.6-0.7-0.7-0.70.70.7-0.70.70.60.6-0.70.7-0.7-0.5
Food consumed during 24 hour testing period0.50.62.70.6-0.2-1.1-1.7-0.5-0.40.10.80.80.6-0.7-0.80.6-0.80.10.10.9-0.61.40.9
Glucose0.40.61.1-1.00.70.91.00.70.6-0.2-0.9-0.9-0.70.80.8-0.80.80.20.2-0.90.9-0.5-0.3
Heart weight0.30.40.8-0.9-0.6-0.6-0.5-0.7-0.80.40.60.60.7-0.6-0.60.7-0.7-0.6-0.60.6-0.70.50.3
Delay discount hyperbolic model param0.10.10.20.5-0.3-0.1-0.3-0.3-0.30.40.30.30.2-0.3-0.30.3-0.3-0.2-0.20.3-0.30.20.3
Intermittent access intake day 1-15 change1.21.21.6-0.01.11.01.01.21.1-1.0-1.1-1.1-1.21.11.1-1.21.11.21.2-1.11.3-1.0-0.9
Intermittent access intake escalation0.60.61.0-0.61.00.70.60.90.9-0.6-0.8-0.8-0.80.80.8-0.80.80.80.8-0.71.0-0.6-0.5
Intermittent access intake escalation 20.20.21.3-1.20.70.0-0.20.50.4-0.4-0.2-0.2-0.30.30.2-0.30.20.30.3-0.10.6-0.1-0.3
Intermitt. access day 1 inactive lever presses1.01.11.6-0.81.11.01.31.11.2-0.9-1.1-1.1-1.11.21.1-1.11.10.70.7-1.21.2-1.1-1.0
Intermitt. access day 15 inactive lever presses1.11.29.33.00.10.90.50.60.8-0.7-1.0-1.0-0.91.01.0-1.01.00.90.9-1.10.8-0.9-0.7
Intermitt. access escalation Index0.60.63.0-1.7-0.3-0.5-0.8-0.5-0.50.70.60.60.7-0.6-0.60.7-0.7-0.8-0.80.6-0.71.10.8
Intermittent access day 1 total infusions0.60.711.6-3.40.7-0.1-0.10.20.4-0.2-0.2-0.1-0.00.20.1-0.00.1-0.2-0.2-0.10.30.6-0.4
Intermittent access day 15 total infusions1.61.815.8-4.01.80.80.71.21.4-0.9-1.0-1.0-1.01.11.0-1.00.90.70.7-0.91.3-0.1-1.0
Intermittent access terminal intake (last 3 days)2.02.28.4-2.91.91.10.91.51.6-1.4-1.4-1.4-1.31.51.3-1.41.31.31.3-1.31.6-0.7-1.4
Intermittent access total infusions2.52.814.5-3.82.11.30.81.61.8-1.7-1.5-1.4-1.41.51.4-1.41.41.31.3-1.41.6-0.6-1.6
Intermittent access day 1 locomotion1.01.11.9-1.3-0.8-1.1-0.7-0.9-1.01.00.90.91.1-0.9-0.91.0-1.0-1.4-1.40.9-1.21.40.7
Intermittent access day 15 total locomotion0.70.71.40.1-0.8-1.0-0.9-0.8-0.70.80.70.80.9-0.7-0.80.8-0.8-1.2-1.20.7-0.61.20.7
Intermittent access total locomotion0.10.10.6-0.8-0.2-0.20.1-0.2-0.20.00.00.10.2-0.1-0.10.2-0.1-0.5-0.50.0-0.20.3-0.2
Intermittent access standard deviation0.20.20.80.9-0.6-0.40.0-0.4-0.40.90.30.30.4-0.4-0.30.4-0.3-0.7-0.70.3-0.30.00.2
Left kidney weight1.33.734.95.90.41.40.60.91.3-1.6-1.2-1.3-1.51.31.3-1.51.42.42.4-1.31.5-1.9-0.8
Right kidney weight2.15.836.16.00.82.21.21.51.7-2.2-1.9-1.9-2.21.92.0-2.12.12.92.9-2.02.1-2.5-1.7
Cocaine induced anxiety1.92.23.4-1.8-1.1-1.6-1.4-1.4-1.41.11.51.51.6-1.5-1.61.6-1.6-1.6-1.61.6-1.51.50.9
Post-drug Anxiety0.91.09.6-3.10.1-0.9-0.8-0.5-0.50.30.80.80.8-0.8-0.90.8-0.9-0.7-0.70.9-0.50.80.3
Baseline Anxiety1.21.31.80.61.01.21.31.21.1-0.8-1.1-1.2-1.21.21.2-1.21.21.21.2-1.21.2-1.3-0.8
Tail length0.10.20.70.40.4-0.1-0.20.20.4-0.6-0.1-0.1-0.30.20.1-0.30.20.80.8-0.10.6-0.2-0.2
Length with tail0.41.53.11.6-1.0-1.6-1.8-1.2-0.90.91.41.31.2-1.2-1.31.2-1.3-0.5-0.51.4-1.11.11.2
Length without tail2.45.26.32.0-2.4-2.5-2.3-2.3-2.32.42.32.32.3-2.3-2.32.3-2.3-2.2-2.22.3-2.52.12.2
Times rat made contact with spout1.41.63.0-0.3-0.9-1.5-1.7-1.1-1.21.11.41.41.3-1.3-1.41.3-1.4-1.1-1.11.4-1.21.61.4
Lifetime Intake1.82.114.6-3.81.91.00.61.31.5-1.3-1.2-1.1-1.11.21.1-1.11.11.01.0-1.11.3-0.3-1.3
Liver weight, left0.20.42.31.5-0.7-0.5-0.7-0.6-0.60.10.60.60.5-0.6-0.60.5-0.60.20.20.6-0.60.50.5
Liver weight, right0.30.54.9-2.20.1-0.4-0.7-0.2-0.50.20.50.50.4-0.5-0.50.5-0.5-0.4-0.40.6-0.40.80.2
Locomotor activity2.74.313.53.7-2.6-2.0-1.8-2.2-2.31.62.02.02.0-2.0-2.02.0-1.9-1.6-1.61.9-2.11.41.6
Locomotor testing distance2.54.15.41.8-2.3-2.1-2.1-2.2-2.31.82.12.12.1-2.1-2.12.1-2.1-1.9-1.92.0-2.01.81.7
Locomotor testing rearing0.50.89.63.1-1.1-0.3-0.5-0.7-0.90.30.60.60.5-0.6-0.50.5-0.5-0.1-0.10.5-0.6-0.10.3
Locomotion in novel chamber1.51.82.41.0-1.6-1.5-1.4-1.3-1.41.31.31.31.4-1.3-1.31.4-1.3-1.4-1.41.2-1.41.31.3
Locomotion in novel chamber post-restriction1.92.33.4-1.6-1.0-1.6-1.4-1.3-1.41.31.51.61.6-1.5-1.61.6-1.6-1.6-1.61.6-1.41.91.3
Fecal boli incidents, locomotor time 12.12.34.8-2.2-0.4-1.5-1.8-1.1-1.01.81.51.51.4-1.5-1.51.4-1.5-1.4-1.41.7-0.91.71.8
Change in fecal boli incidents, locomotor task0.30.30.6-0.70.50.50.70.50.50.0-0.6-0.6-0.50.60.6-0.60.60.10.1-0.60.4-0.4-0.3
Time >=10cm from walls, locomotor time 11.21.216.2-4.00.4-0.7-0.7-0.1-0.30.70.60.60.6-0.6-0.70.6-0.7-1.0-1.00.7-0.51.00.6
Bouts of movement, locomotor time 10.30.44.0-2.0-0.2-0.2-0.1-0.3-0.30.60.30.30.4-0.4-0.30.4-0.4-0.6-0.60.3-0.70.40.3
Total resting periods, locomotor time 10.20.23.9-2.00.1-0.00.1-0.10.00.50.00.10.2-0.1-0.10.2-0.1-0.4-0.40.0-0.30.10.2
Rest time, locomotor task time 10.40.56.4-2.50.0-0.20.0-0.3-0.00.90.10.10.3-0.2-0.20.3-0.2-0.7-0.70.1-0.00.30.4
Distance moved, locomotor task time 10.30.45.92.4-0.5-0.2-0.4-0.3-0.3-0.10.30.30.2-0.2-0.30.2-0.2-0.1-0.10.3-0.10.20.1
Vertical activity count, locomotor time 11.11.25.12.3-0.9-1.1-1.6-0.9-0.90.21.11.10.9-1.0-1.10.9-1.0-0.4-0.41.1-0.91.10.9
Time >=10cm from walls, locomotor time 20.80.86.2-2.51.10.90.91.00.7-0.4-0.7-0.7-0.70.70.7-0.70.70.40.4-0.70.5-0.6-0.7
Bouts of movement, locomotor time 20.91.01.3-1.11.01.00.71.00.9-1.1-1.0-1.0-1.01.01.0-1.01.00.90.9-1.00.8-1.0-1.1
Total resting periods, locomotor time 21.11.21.4-1.11.11.20.81.11.1-1.2-1.2-1.2-1.11.11.2-1.11.11.01.0-1.20.9-1.2-1.1
Rest time, locomotor task time 21.31.517.9-4.21.60.80.51.01.1-0.1-0.8-0.8-0.70.80.7-0.70.70.20.2-0.70.9-0.4-0.3
Distance moved, locomotor task time 21.51.720.84.6-1.7-0.6-0.3-1.1-1.20.70.80.80.8-0.8-0.70.8-0.7-0.6-0.60.7-1.10.40.5
Vertical activity count, locomotor time 21.92.112.43.5-1.7-1.2-1.2-1.4-1.40.91.31.31.2-1.3-1.31.2-1.2-0.9-0.91.2-1.31.11.0
Light reinforcement 13.56.417.84.2-2.9-2.5-2.7-2.6-2.71.82.52.52.4-2.5-2.42.4-2.4-1.6-1.62.4-2.72.32.2
Light reinforcement 23.14.16.62.6-2.2-2.0-2.1-2.0-2.12.02.02.02.0-2.0-2.02.0-2.0-1.9-1.92.0-1.91.92.1
Bone: marrow area0.00.10.2-0.40.0-0.5-0.2-0.0-0.20.30.30.30.2-0.2-0.30.2-0.2-0.3-0.30.3-0.20.20.4
Bone: maximum diameter0.81.52.31.2-1.2-1.5-1.5-1.3-1.01.21.31.31.2-1.2-1.31.2-1.2-1.0-1.01.3-1.11.11.3
Bone: maximum force0.20.30.50.00.40.60.60.60.6-0.5-0.6-0.6-0.60.60.6-0.60.60.50.5-0.60.5-0.7-0.5
Bone: maximum moment0.00.00.1-0.00.10.10.30.20.20.1-0.2-0.2-0.10.20.2-0.20.2-0.1-0.1-0.20.1-0.30.0
Mean time between licks in bursts0.20.23.92.0-0.2-0.3-0.6-0.20.2-0.00.10.10.0-0.0-0.10.0-0.10.10.10.10.3-0.00.2
Mean num. licks in bursts0.10.10.9-1.00.4-0.1-0.40.20.2-0.1-0.0-0.0-0.10.00.0-0.10.00.20.20.00.20.30.1
Cd content in liver0.30.31.51.20.20.4-0.10.20.4-0.9-0.3-0.3-0.40.30.4-0.40.41.01.0-0.30.4-0.4-0.5
Co content in liver0.00.00.5-0.70.30.0-0.20.00.2-0.1-0.1-0.1-0.10.10.1-0.10.10.10.1-0.10.20.30.0
Cu content in liver0.50.60.9-0.91.00.80.61.00.8-0.7-0.8-0.8-0.80.80.8-0.80.80.70.7-0.80.8-0.5-0.7
Fe content in liver0.50.61.00.1-0.8-0.5-0.5-0.8-0.90.90.70.70.7-0.8-0.70.8-0.7-1.0-1.00.6-0.90.70.7
K content in liver0.20.21.5-1.20.50.10.60.40.20.6-0.3-0.3-0.20.30.2-0.30.3-0.6-0.6-0.20.3-0.30.1
Mg content in liver0.20.20.7-0.7-0.0-0.40.0-0.1-0.20.80.20.20.3-0.2-0.20.2-0.2-0.8-0.80.2-0.20.20.4
Mn content in liver0.50.61.40.3-0.7-0.8-0.4-0.6-0.71.10.70.70.8-0.7-0.70.7-0.7-1.2-1.20.6-0.70.40.7
Na content in liver0.50.61.6-1.10.70.71.30.70.60.9-0.7-0.7-0.60.60.6-0.60.7-0.8-0.8-0.70.6-0.9-0.1
Rb content in liver0.20.30.5-0.60.40.50.70.50.4-0.6-0.5-0.5-0.50.50.5-0.50.50.60.6-0.50.4-0.6-0.6
Se content in liver0.10.10.90.9-0.10.0-0.1-0.20.1-0.3-0.0-0.0-0.00.00.0-0.00.00.20.2-0.00.2-0.3-0.3
Sr content in liver1.31.22.01.4-1.1-1.4-1.2-1.0-1.20.51.21.21.1-1.1-1.21.1-1.2-0.5-0.51.2-1.21.10.8
Zn content in liver4.04.45.5-1.32.32.12.22.32.2-2.0-2.1-2.2-2.22.22.1-2.32.22.02.0-2.12.2-1.9-2.0
Bone: minimum diameter0.30.51.31.1-0.7-0.8-0.8-0.7-0.40.80.60.60.6-0.6-0.60.6-0.6-0.6-0.60.6-0.40.40.9
Time in familiar zone, hab. session 10.40.40.80.8-0.6-0.8-0.7-0.7-0.20.80.50.50.6-0.5-0.50.6-0.5-0.7-0.70.5-0.30.80.9
Time in novel zone, hab. session 10.50.41.5-1.20.60.80.80.70.2-0.8-0.5-0.5-0.60.50.6-0.50.50.60.6-0.50.3-0.8-1.0
Total zone transitions, hab. session 10.81.21.41.0-1.1-1.1-1.2-1.1-1.21.01.11.11.1-1.1-1.11.1-1.1-0.9-0.91.1-1.01.11.1
Total locomotion distance, hab. session 11.01.42.00.6-1.2-1.2-1.3-1.1-1.40.81.31.21.2-1.3-1.21.2-1.3-0.8-0.81.3-1.31.41.0
Locomotion velocity, hab. session 11.21.72.50.7-1.3-1.4-1.5-1.3-1.60.91.41.41.3-1.4-1.41.4-1.4-0.8-0.81.5-1.51.51.1
Time in familiar zone, hab. session 20.90.91.80.6-1.0-1.0-0.6-1.0-0.81.30.90.91.0-0.9-0.91.0-0.9-1.3-1.30.8-0.90.71.0
Time in novel zone, hab. session 24.74.76.0-2.12.32.52.32.32.0-2.1-2.2-2.2-2.22.22.2-2.22.22.02.0-2.22.1-2.1-2.1
Total zone transitions, hab. session 21.92.53.61.9-1.8-1.5-1.6-1.7-1.71.51.61.61.5-1.7-1.61.6-1.6-1.3-1.31.6-1.61.31.6
Total locomotion distance, hab. session 21.11.52.01.2-1.3-1.2-1.4-1.3-1.40.91.31.31.2-1.3-1.31.2-1.3-0.7-0.71.3-1.41.41.2
Locomotion velocity, hab. session 21.11.52.31.5-1.3-1.2-1.5-1.3-1.40.81.31.31.2-1.3-1.31.2-1.3-0.6-0.61.3-1.31.31.2
Novel to familiar place preference ratio1.61.72.5-1.01.21.61.61.31.4-0.8-1.5-1.5-1.31.41.4-1.41.50.70.7-1.51.4-1.1-1.0
Novelty place preference2.72.84.4-1.51.62.02.11.61.7-1.1-1.9-1.8-1.71.81.8-1.71.81.01.0-1.91.7-1.6-1.4
Time in novel zone, NPP test2.42.54.2-1.61.51.92.11.61.6-1.0-1.8-1.7-1.61.71.7-1.61.70.90.9-1.81.6-1.5-1.3
Total zone transitions, NPP test1.72.54.01.8-1.6-1.6-2.0-1.6-1.81.21.61.61.5-1.6-1.61.6-1.6-1.0-1.01.6-1.61.71.5
Total locomotion distance, NPP test1.01.32.40.9-1.1-1.0-1.6-1.1-1.40.71.21.21.1-1.2-1.21.1-1.2-0.6-0.61.2-1.31.51.1
Locomotion velocity, NPP test0.81.22.41.0-1.1-0.9-1.6-1.0-1.30.61.21.11.0-1.2-1.11.1-1.1-0.4-0.41.2-1.21.41.0
Intraocular pressure0.81.16.22.50.20.90.70.50.5-1.4-0.7-0.7-0.80.70.8-0.80.81.51.5-0.80.6-0.9-1.0
Delta distance traveled before/after self-admin0.91.03.2-1.81.10.91.21.11.0-0.6-1.0-1.0-0.91.00.9-0.90.90.50.5-1.01.0-0.8-1.0
Delta ambulatory time before/after self-admin1.92.118.2-4.31.81.01.21.51.4-0.9-1.1-1.1-1.11.21.1-1.11.00.60.6-1.01.3-0.7-1.2
Parametrial fat weight5.210.118.54.3-3.5-3.2-3.1-3.3-3.13.03.23.23.1-3.2-3.13.1-3.1-2.7-2.73.1-3.22.73.1
Pavlov. Cond. lever latency0.10.10.6-0.1-0.1-0.6-0.3-0.30.20.60.20.20.4-0.2-0.30.3-0.2-0.7-0.70.20.10.20.3
Pavlov. Cond. magazine entry latency0.40.61.3-0.30.90.80.30.90.6-0.9-0.6-0.7-0.80.70.7-0.80.71.21.2-0.60.6-0.5-0.6
Pavlov. Cond. change in total contacts0.80.81.40.60.71.00.90.90.8-0.9-0.9-0.9-1.00.91.0-1.01.01.21.2-0.90.9-0.9-0.7
Pavlov. Cond. index score0.40.51.50.30.60.70.30.70.4-1.0-0.5-0.6-0.70.50.6-0.70.61.21.2-0.50.4-0.6-0.6
Pavlov. Cond. latency score0.30.31.10.20.50.60.20.60.2-0.8-0.4-0.4-0.60.40.5-0.60.51.11.1-0.40.3-0.4-0.4
Pavlov. Cond. lever contacts0.20.30.60.00.40.70.60.50.2-0.6-0.4-0.5-0.50.40.5-0.50.50.80.8-0.40.2-0.6-0.5
Pavlov. Cond. magazine entry number0.70.91.70.7-1.1-0.9-0.7-1.1-0.91.10.80.91.0-0.9-0.91.0-0.9-1.3-1.30.8-0.90.80.8
Pavlov. Cond. intertrial magazine entries0.20.20.5-0.2-0.4-0.7-0.4-0.5-0.40.20.50.50.5-0.4-0.50.5-0.5-0.4-0.40.5-0.40.50.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.40.40.50.70.30.60.3-0.9-0.5-0.5-0.70.50.5-0.60.51.21.2-0.40.4-0.5-0.5
Pavlov. Cond. response bias0.10.10.4-0.10.30.40.10.40.0-0.5-0.2-0.2-0.30.20.2-0.30.20.60.6-0.10.1-0.3-0.2
Pavlov. Cond. lever latency1.31.83.7-0.1-1.3-1.4-0.8-1.3-1.21.81.21.21.4-1.2-1.31.3-1.2-1.9-1.91.2-1.11.21.4
Pavlov. Cond. magazine entry latency3.23.75.6-0.41.82.11.71.91.8-2.3-1.9-1.9-2.01.91.9-2.01.92.42.4-1.91.7-1.9-2.0
Pavlov. Cond. change in total contacts1.92.66.31.71.11.60.91.31.5-2.2-1.3-1.4-1.61.41.5-1.61.42.52.5-1.41.3-1.6-1.5
Pavlov. Cond. index score3.13.96.9-0.31.92.11.51.91.9-2.5-1.9-1.9-2.11.91.9-2.01.92.62.6-1.91.8-1.9-2.1
Pavlov. Cond. latency score3.44.27.4-0.21.92.21.72.01.9-2.6-1.9-2.0-2.12.02.0-2.12.02.72.7-1.91.8-2.0-2.1
Pavlov. Cond. lever contacts1.41.94.2-0.31.41.40.81.31.2-2.0-1.2-1.2-1.41.21.2-1.31.22.12.1-1.11.1-1.3-1.5
Pavlov. Cond. magazine entry number5.56.79.50.6-2.4-2.8-2.3-2.6-2.43.02.62.62.7-2.6-2.62.7-2.6-3.1-3.12.6-2.42.62.6
Pavlov. Cond. intertrial magazine entries4.65.97.31.6-2.5-2.7-2.0-2.5-2.42.52.52.52.5-2.5-2.52.5-2.5-2.4-2.42.5-2.52.32.5
Pavlov. Cond. lever-magazine prob. diff.3.74.77.8-0.62.12.31.72.12.1-2.7-2.1-2.1-2.32.12.1-2.22.12.82.8-2.02.0-2.1-2.2
Pavlov. Cond. response bias2.43.36.5-0.01.72.01.31.71.6-2.4-1.6-1.7-1.91.71.7-1.81.72.62.6-1.61.5-1.8-1.9
Time in closed arm before self-admin3.03.414.53.8-2.3-1.6-1.7-1.8-2.01.91.61.61.6-1.6-1.61.6-1.5-1.5-1.51.5-1.71.31.7
Time in closed arm after self-admin2.62.77.42.7-2.0-1.5-1.5-1.7-1.61.71.51.51.6-1.5-1.51.5-1.5-1.5-1.51.4-1.71.31.4
Time in open arm before self-admin1.71.84.2-2.01.81.20.51.51.5-1.8-1.1-1.1-1.31.21.1-1.21.11.71.7-1.01.3-0.9-1.1
Time in open arm after self-admin0.60.61.30.40.70.90.90.80.7-0.7-0.8-0.8-0.90.80.8-0.90.90.80.8-0.80.6-1.1-0.5
Bone: periosteal estimation0.30.61.11.0-0.7-1.0-0.9-0.7-0.70.80.80.80.7-0.8-0.80.7-0.8-0.6-0.60.8-0.70.60.9
Bone: periosteal perimeter1.11.84.12.0-1.3-1.6-1.9-1.4-1.20.91.41.41.3-1.3-1.41.3-1.4-0.6-0.61.4-1.21.41.3
Bone: post-yield work0.60.81.50.5-1.0-1.1-0.6-1.1-0.81.10.80.81.0-0.8-0.80.9-0.8-1.2-1.20.8-0.80.80.9
Progressive ratio test 1 active lever presses3.03.112.1-3.52.21.51.11.81.7-2.0-1.6-1.6-1.61.71.6-1.61.51.71.7-1.51.4-0.7-1.8
Progressive ratio test 1 breakpoint2.82.95.2-2.32.01.51.31.81.7-2.0-1.7-1.7-1.71.71.7-1.71.61.81.8-1.61.4-1.0-1.8
Progressive ratio test 1 inactive lever presses0.91.05.9-2.41.20.81.01.00.9-0.8-0.9-0.9-0.80.90.9-0.90.90.50.5-0.90.7-0.5-0.8
Progressive ratio test 2 active lever presses3.53.828.6-5.32.61.31.01.91.8-1.7-1.5-1.5-1.51.61.5-1.51.51.41.4-1.41.7-0.5-1.6
Progressive ratio test 2 breakpoint3.13.523.4-4.82.41.41.01.81.8-1.7-1.6-1.5-1.51.61.5-1.51.51.41.4-1.41.6-0.6-1.6
Progressive ratio test 2 inactive lever presses0.20.20.6-0.80.40.40.40.40.4-0.5-0.6-0.5-0.40.50.5-0.50.50.20.2-0.60.3-0.2-0.6
Incentive Sensitization - Responses2.32.330.4-5.52.00.70.21.11.2-1.0-0.9-0.8-0.80.90.8-0.80.70.60.6-0.71.10.1-0.9
Incentive Sensitization - Breakpoint2.42.431.2-5.62.10.70.21.21.2-1.0-0.9-0.9-0.90.90.8-0.90.80.60.6-0.71.10.1-1.0
Sum of active levers in priming session hrs 5-60.20.20.50.6-0.00.50.70.30.2-0.6-0.5-0.5-0.40.40.5-0.40.50.50.5-0.5-0.1-0.7-0.6
Progressive ratio1.31.626.05.1-1.00.5-0.0-0.2-0.3-0.6-0.0-0.1-0.2-0.00.1-0.20.11.11.1-0.1-0.5-0.6-0.2
Food seeking constrained by brief footshock1.41.72.11.21.01.51.31.31.3-1.0-1.3-1.3-1.41.31.4-1.41.41.41.4-1.31.2-1.4-1.0
Seeking ratio, punishment vs. effort1.11.312.0-3.51.60.50.91.11.2-0.3-0.9-0.9-0.80.90.8-0.80.80.10.1-0.81.3-0.3-0.5
Retroperitoneal fat weight4.514.717.83.0-4.0-4.2-3.8-4.0-3.93.63.93.93.9-3.9-3.93.9-3.9-3.5-3.53.9-3.93.93.8
Reaction time number correct1.82.69.2-3.01.91.51.61.81.5-1.7-1.4-1.4-1.51.51.4-1.51.41.41.4-1.41.2-1.2-1.7
Reaction time mean minus median1.21.54.62.10.31.41.10.70.7-1.4-1.1-1.1-1.11.01.1-1.11.11.51.5-1.20.9-1.7-1.4
Reaction time mean minus median AUC1.31.78.83.00.11.31.10.60.7-1.5-1.0-1.0-1.10.91.1-1.01.11.71.7-1.10.7-1.8-1.4
Reaction time num false alarms0.20.21.2-1.10.50.40.40.50.4-0.3-0.5-0.5-0.40.50.4-0.40.50.10.1-0.50.4-0.3-0.4
Reaction time num false alarms AUC0.10.12.6-1.60.3-0.1-0.20.2-0.0-0.1-0.0-0.00.00.1-0.00.0-0.0-0.2-0.20.0-0.10.3-0.1
Reaction time trials correct on left1.82.69.2-3.01.91.51.61.81.5-1.7-1.4-1.4-1.51.51.4-1.51.41.41.4-1.41.2-1.2-1.7
Reaction time trials on left1.92.79.8-3.11.91.51.61.81.6-1.7-1.5-1.5-1.51.51.4-1.51.41.51.5-1.41.2-1.2-1.7
Reaction time mean1.31.933.85.8-1.30.50.1-0.5-0.3-0.1-0.2-0.2-0.20.10.3-0.20.30.50.5-0.4-0.1-0.8-0.2
Reaction time mean AUC1.21.626.45.1-0.90.80.4-0.20.1-0.3-0.5-0.5-0.50.40.6-0.50.60.70.7-0.70.3-1.1-0.4
Median of all reaction times1.52.036.36.0-1.50.1-0.3-0.8-0.50.30.10.10.1-0.2-0.00.10.00.10.1-0.1-0.3-0.40.3
Reaction time omissions0.30.42.5-1.60.4-0.6-1.5-0.1-0.1-0.50.50.50.3-0.4-0.50.3-0.50.60.60.6-0.20.90.2
Reaction time false alarm rate0.40.50.90.0-0.6-0.8-1.0-0.7-0.70.80.70.70.7-0.6-0.70.7-0.7-0.9-0.90.7-0.60.80.8
Reaction time premature initiation rate1.21.62.81.20.81.41.31.11.3-1.0-1.3-1.3-1.31.21.3-1.31.31.41.4-1.30.9-1.7-1.0
Reaction time premature initiations2.84.04.9-0.71.92.22.12.12.2-1.9-2.0-2.0-2.12.02.1-2.12.12.12.1-2.01.6-2.2-1.9
Std. dev. reaction times0.71.012.13.5-0.50.90.60.00.2-0.5-0.5-0.5-0.50.40.6-0.50.60.80.8-0.70.3-1.2-0.6
Reaction time trials completed1.92.79.8-3.11.91.51.61.81.6-1.7-1.5-1.5-1.51.51.4-1.51.41.51.5-1.41.2-1.2-1.7
Reaction time trials AUC1.82.69.3-3.01.91.51.61.81.6-1.7-1.5-1.5-1.51.51.4-1.51.41.41.4-1.41.2-1.1-1.7
Run reversals in cocaine runway, females2.82.73.90.5-1.3-1.9-1.9-1.7-1.41.91.71.71.6-1.6-1.71.6-1.6-1.7-1.71.7-1.41.92.0
Run reversals in cocaine runway, males0.90.93.8-1.90.1-0.8-1.5-0.5-0.50.80.80.80.7-0.8-0.80.7-0.8-0.8-0.80.9-0.41.41.0
Latency to leave start box in cocaine runway0.30.31.10.90.10.61.00.40.40.0-0.6-0.6-0.50.50.6-0.50.60.20.2-0.70.5-0.9-0.3
Latency to leave start box in cocaine runway, F1.82.010.7-3.31.51.31.81.31.4-0.6-1.4-1.3-1.11.31.3-1.21.30.40.4-1.41.4-1.2-1.2
Latency to leave start box in cocaine runway, M2.82.740.46.4-2.1-0.5-0.2-1.2-1.21.00.70.70.7-0.8-0.60.7-0.6-0.3-0.30.5-1.0-0.40.8
Std. dev. time between licks in bursts2.63.24.02.0-1.8-2.0-2.0-1.7-1.81.61.91.91.8-1.8-1.81.8-1.8-1.4-1.41.9-1.71.61.8
Total sessions with >9 infusions3.03.353.2-7.32.20.3-0.51.11.0-1.0-0.5-0.5-0.60.60.4-0.50.40.60.6-0.30.70.8-0.8
Short access day 1 total inactive lever presses0.10.11.1-1.00.20.20.40.00.30.5-0.2-0.2-0.10.10.2-0.10.2-0.4-0.4-0.20.2-0.3-0.0
Short access day 10 total inactive lever presses0.60.69.13.0-0.40.40.60.10.1-0.2-0.3-0.3-0.30.30.4-0.40.40.30.3-0.40.3-1.1-0.2
Short access day 1 total infusions1.11.120.4-4.51.1-0.1-0.40.40.5-0.2-0.1-0.1-0.10.10.0-0.0-0.0-0.1-0.10.10.10.7-0.3
Short access day 10 total infusions0.50.68.2-2.90.4-0.5-1.0-0.20.10.20.30.30.4-0.2-0.40.4-0.4-0.4-0.40.4-0.11.00.1
Short access total infusions0.70.89.1-3.01.20.4-0.00.70.9-0.6-0.6-0.5-0.50.60.5-0.50.50.50.5-0.50.60.1-0.7
Short access day 1 locomotion0.30.32.1-1.50.80.40.10.60.6-0.1-0.4-0.4-0.50.40.4-0.50.40.50.5-0.30.20.1-0.0
Short access day 10 total locomotion1.51.72.71.2-1.6-1.3-0.6-1.4-1.31.41.21.21.4-1.2-1.21.3-1.2-1.6-1.61.1-1.51.31.0
Short access total locomotion0.60.62.91.7-1.2-0.7-0.3-0.8-0.60.90.60.60.7-0.6-0.60.7-0.6-0.9-0.90.5-1.00.60.5
One hour access (0.3 mA shock)1.21.44.2-2.11.61.00.41.11.4-1.4-1.1-1.1-1.11.11.1-1.11.01.21.2-1.01.4-0.4-1.2
Compulsive drug intake0.80.83.11.80.41.00.80.50.7-0.6-0.7-0.8-0.90.70.8-0.80.81.11.1-0.80.9-1.0-0.4
One hour access (shock baseline)1.31.517.0-4.11.60.60.11.11.1-1.0-0.8-0.8-0.70.90.7-0.70.70.50.5-0.71.00.1-1.0
Social response proportion1.31.511.9-3.41.60.60.71.01.1-1.3-0.9-0.8-0.81.00.8-0.80.80.90.9-0.81.2-0.4-1.2
Social responses0.20.23.5-1.90.3-0.30.10.00.1-0.30.10.20.1-0.1-0.20.2-0.20.10.10.20.00.0-0.3
Social time0.20.22.5-1.60.5-0.4-0.10.10.5-0.6-0.0-0.0-0.10.20.0-0.0-0.00.40.40.00.30.2-0.5
Soleus weight0.20.62.91.7-0.9-0.7-0.6-0.8-0.70.60.70.70.6-0.7-0.70.7-0.7-0.5-0.50.7-0.70.30.6
Bone: stiffness2.94.65.9-0.32.12.12.02.22.3-2.3-2.1-2.1-2.22.22.1-2.22.22.42.4-2.12.2-2.2-2.1
Tibialis anterior weight0.20.72.01.40.50.60.50.70.6-1.2-0.6-0.6-0.80.60.6-0.80.61.31.3-0.60.6-0.8-0.8
Time to tail flick, vehicle, before self-admin1.81.919.3-4.41.80.80.41.31.1-0.8-0.9-0.9-0.91.00.9-0.90.80.80.8-0.81.0-0.4-1.1
Time to tail flick, vehicle, after self-admin1.01.14.9-2.2-0.5-1.0-1.2-0.7-1.00.60.91.01.0-0.9-1.01.0-1.0-1.0-1.01.0-1.01.40.5
Time to tail flick, test, before self-admin1.51.43.5-0.6-0.6-1.4-1.9-1.3-1.00.71.31.31.2-1.3-1.31.3-1.4-0.9-0.91.4-0.61.51.0
Time to tail flick, test, after self-admin0.50.55.5-2.30.1-0.9-0.3-0.4-0.1-0.10.50.60.6-0.4-0.60.6-0.6-0.3-0.30.6-0.30.90.1
Delta time to tail flick, vehicle, before/after SA1.61.62.00.3-1.3-1.4-1.2-1.4-1.40.71.41.41.4-1.4-1.41.4-1.4-1.2-1.21.4-1.31.41.0
Delta time to tail flick, test, before/after SA0.40.31.6-1.30.70.30.80.60.6-0.5-0.5-0.5-0.50.50.5-0.50.50.50.5-0.40.4-0.3-0.5
Tibia length0.00.11.21.1-0.10.2-0.2-0.20.2-0.1-0.1-0.1-0.10.00.1-0.10.10.30.3-0.10.2-0.20.1
Ambulatory time before self-admin3.73.835.76.0-2.4-1.3-1.4-1.7-1.42.11.31.31.3-1.4-1.31.2-1.2-1.2-1.21.2-1.50.91.8
Ambulatory time after self-admin0.80.81.80.8-0.8-0.9-1.1-0.7-0.71.20.80.80.8-0.8-0.80.8-0.7-1.1-1.10.8-0.81.11.4
Bone: tissue strength0.50.52.8-1.70.40.41.10.50.70.4-0.6-0.6-0.30.60.5-0.40.6-0.6-0.6-0.70.6-0.4-0.1
Total heroin consumption1.21.44.7-2.21.21.21.61.21.1-0.6-1.2-1.1-1.11.11.1-1.11.10.80.8-1.11.1-1.1-0.9
Bone: trabecular number0.50.75.42.3-1.1-0.5-0.4-0.9-0.60.90.70.60.7-0.7-0.60.7-0.6-0.6-0.60.6-0.80.30.9
Bone: trabecular spacing0.10.11.0-1.00.1-0.5-0.10.0-0.20.10.20.20.2-0.1-0.20.2-0.2-0.3-0.30.2-0.10.2-0.0
Bone: trabecular thickness0.30.41.00.60.41.00.50.40.6-0.7-0.6-0.6-0.60.50.6-0.60.60.80.8-0.60.6-0.6-0.5
Bone: trabecular tissue density0.71.01.8-1.31.01.11.21.00.9-0.9-1.1-1.0-1.01.01.0-1.01.00.70.7-1.10.9-1.1-1.1
Water consumed over 24 hours0.60.71.21.0-0.7-1.1-1.1-0.8-0.70.60.90.90.8-0.8-0.90.8-0.9-0.5-0.50.9-0.60.90.8
Number of responses in last shaping day1.31.314.03.7-0.11.00.90.60.8-0.4-0.9-0.9-0.90.80.9-0.91.00.90.9-1.00.5-0.9-0.3