Hub : Genes

Zbtb7a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA NM_054002.2 0.04 0.04 7.0e-04 0.01 0.02 0.02 0.02 1.8e-02 3.2e-03 2.2e-03 5.6e-03
2 Adipose alternative TSS XM_006240836.4 0.05 0.04 4.3e-05 0.04 0.03 0.03 0.03 4.8e-05 2.4e-04 1.4e-04 1.2e-04
3 Adipose isoform ratio XM_006240836.4 0.05 0.04 2.7e-04 0.03 0.02 0.03 0.03 2.5e-04 1.1e-03 3.8e-04 3.1e-04
4 NAcc mRNA stability Zbtb7a 0.04 0.03 1.2e-04 0.03 0.03 0.03 0.03 9.2e-05 1.5e-04 1.1e-04 1.0e-04
5 NAcc isoform ratio XM_006240837.4 0.04 0.03 1.3e-03 0.01 0.02 0.02 0.02 2.7e-02 2.2e-03 1.3e-03 3.6e-03
6 Adipose isoform ratio XM_006240837.4 0.05 0.05 5.5e-05 0.02 0.03 0.01 0.03 2.0e-03 2.3e-04 8.6e-03 2.9e-04
7 BLA alternative polyA NM_054002.2 0.1 0.08 1.1e-03 0.04 0.03 0.04 0.03 2.9e-03 6.8e-03 3.0e-03 1.1e-02
8 BLA alternative polyA XM_006240838.4 0.06 0.05 1.7e-03 0.04 0.03 0.04 0.03 4.2e-03 8.2e-03 4.7e-03 9.6e-03
9 Brain alternative polyA NM_054002.2 0.04 0.03 4.0e-03 0.02 0.01 0 0.01 6.0e-03 4.0e-02 1.1e-01 4.3e-02
10 Brain alternative polyA XM_006240838.4 0.03 0.03 6.2e-03 0.02 0.01 0 0.01 8.0e-03 4.5e-02 1.1e-01 4.8e-02
11 Brain isoform ratio NM_054002.2 0.05 0.04 2.3e-03 0.02 0.01 0.01 0.01 3.2e-03 1.4e-02 1.8e-02 1.8e-02
12 Adipose isoform ratio NM_054002.2 0.06 0.06 5.6e-06 0.04 0.04 0.04 0.04 2.0e-05 3.1e-05 6.3e-05 3.1e-05
13 Adipose alternative polyA NM_054002.2 0.04 0.03 3.8e-05 0.03 0.03 0.03 0.03 9.6e-05 2.1e-04 7.3e-04 2.2e-04
14 Adipose alternative polyA XM_006240838.4 0.04 0.04 3.9e-05 0.03 0.03 0.02 0.03 1.1e-04 2.6e-04 1.0e-03 3.1e-04
15 Adipose gene expression Zbtb7a 0.03 0.02 4.8e-03 0.02 0.01 0.01 0.01 5.9e-03 1.0e-02 2.2e-02 1.0e-02
16 Adipose mRNA stability Zbtb7a 0.02 0.02 4.3e-03 0.01 0.01 0 0.01 7.3e-03 2.2e-02 7.4e-02 2.9e-02
17 NAcc alternative polyA XM_006240838.4 0.05 0.04 5.8e-04 0.01 0.02 0.03 0.02 4.1e-02 8.7e-04 5.3e-04 1.7e-03
18 NAcc alternative polyA NM_054002.2 0.04 0.04 1.1e-03 0 0.03 0.02 0.02 7.9e-02 4.1e-04 7.3e-04 1.0e-03
19 PL isoform ratio NM_054002.2 0.06 0.04 1.7e-04 0.01 0.04 0.03 0.03 2.8e-02 8.3e-05 1.7e-04 2.2e-04
20 PL alternative polyA XM_006240838.4 0.03 0.03 2.0e-03 0.01 0.01 0.01 0.01 4.4e-02 1.3e-02 1.0e-02 2.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.81.34.6-1.51.21.2-1.20.60.0-0.60.6-0.60.6-0.6-0.6-0.60.6-0.6-0.61.52.12.12.0
Area under the delay curve2.12.22.8-1.0-1.3-1.21.21.7-1.6-1.61.6-1.61.6-1.6-1.6-1.61.6-1.6-1.71.51.51.50.3
BMI with tail5.818.724.9-4.6-4.7-4.64.65.0-4.7-4.64.6-4.64.6-4.6-4.6-4.64.6-4.6-4.63.82.82.71.6
BMI without tail2.14.415.0-3.9-2.4-2.42.42.7-2.2-2.02.0-2.02.0-2.0-2.0-2.02.0-2.0-2.01.60.70.61.5
Body weight1.04.05.6-1.0-2.3-2.42.42.0-2.3-2.22.2-2.22.2-2.2-2.2-2.22.2-2.2-2.11.71.31.2-0.1
Weight adjusted by age0.40.55.0-2.2-0.8-0.80.80.9-0.5-0.30.3-0.30.3-0.3-0.4-0.40.4-0.4-0.30.2-0.4-0.50.9
Bone surface1.22.28.3-1.72.22.2-2.20.30.6-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.31.62.62.72.9
Bone volume1.32.28.2-1.72.22.2-2.20.30.6-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.31.62.62.72.9
Breakpoint value in progressive ratio session5.15.67.11.12.12.0-2.0-2.42.62.7-2.72.7-2.72.72.62.6-2.62.62.7-2.3-2.3-2.3-0.3
Number of licking bursts0.30.31.61.0-0.8-0.80.8-0.2-0.20.0-0.00.0-0.00.00.20.2-0.20.20.2-0.6-1.0-1.0-1.3
Context. condit. distance diff. score0.20.30.5-0.2-0.6-0.70.70.6-0.6-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.60.40.30.3-0.1
Locomotion velocity, session 10.50.51.8-0.51.31.3-1.3-0.40.80.6-0.60.6-0.60.60.50.5-0.50.50.40.10.50.51.1
Locomotion distance, session 10.40.52.7-1.10.91.0-1.00.20.3-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.20.81.21.21.6
Locomotion velocity, session 22.42.87.1-0.12.62.7-2.7-1.52.01.6-1.61.6-1.61.61.61.6-1.61.61.5-0.60.10.21.5
Locomotion distance, session 21.01.44.6-0.42.02.1-2.1-0.91.40.9-0.90.9-0.90.91.01.0-1.01.00.9-0.00.60.61.6
Locomotion velocity, session 35.46.37.61.92.62.5-2.5-2.72.82.8-2.82.8-2.82.82.72.7-2.72.72.7-2.3-1.9-1.9-0.5
Locomotion distance, session 30.00.00.0-0.00.00.0-0.0-0.00.00.2-0.20.2-0.20.20.10.1-0.10.10.0-0.2-0.2-0.2-0.2
Stereotopy head waving bouts, day 33.74.36.41.12.52.5-2.5-2.22.42.2-2.22.2-2.22.22.22.2-2.22.22.2-1.6-1.1-1.00.4
Stereotopy head waving duration, day 34.55.37.11.52.62.6-2.6-2.52.72.5-2.52.5-2.52.52.52.5-2.52.52.5-1.9-1.4-1.40.1
Locomotion velocity, session 70.60.61.20.31.01.1-1.1-0.81.00.8-0.80.8-0.80.80.80.8-0.80.80.8-0.5-0.3-0.20.3
Locomotion distance, session 70.10.10.60.3-0.5-0.50.50.1-0.3-0.00.0-0.00.0-0.0-0.1-0.10.1-0.1-0.1-0.3-0.5-0.5-0.7
Stereotopy head waving bouts, day 70.30.31.5-0.90.60.5-0.50.30.0-0.20.2-0.20.2-0.2-0.3-0.30.3-0.3-0.30.71.11.11.2
Stereotopy head waving duration, day 70.30.41.8-0.61.00.9-0.9-0.10.50.1-0.10.1-0.10.10.10.1-0.10.10.10.50.91.01.3
Locomotion velocity, session 80.50.62.9-0.81.41.4-1.4-0.30.70.3-0.30.3-0.30.30.30.3-0.30.30.30.51.01.11.7
Locomotion distance, session 80.10.10.3-0.20.50.6-0.6-0.20.30.1-0.10.1-0.10.10.20.2-0.20.20.20.10.30.30.5
Degree of sensitization distance0.30.30.5-0.4-0.6-0.60.60.6-0.6-0.70.7-0.70.7-0.7-0.6-0.60.6-0.6-0.60.60.50.40.1
Degree of sensitization stereotypy2.12.33.3-1.7-0.9-0.90.91.6-1.4-1.61.6-1.61.6-1.6-1.6-1.61.6-1.6-1.61.81.81.81.2
Conditioned locomotion1.21.44.0-0.3-2.0-2.02.01.0-1.4-1.11.1-1.11.1-1.1-1.1-1.11.1-1.1-1.00.4-0.2-0.3-0.8
Cocaine response after cond. corrected3.74.18.7-0.9-2.9-2.92.92.1-2.5-2.12.1-2.12.1-2.1-2.0-2.02.0-2.0-2.11.20.50.4-0.7
Cocaine response after cond. not corrected3.94.39.4-0.9-3.1-3.13.12.1-2.5-2.12.1-2.12.1-2.1-2.1-2.12.1-2.1-2.11.20.40.3-0.8
Cocaine response before conditioning0.40.41.00.11.01.0-1.0-0.70.80.7-0.70.7-0.70.70.60.6-0.60.60.7-0.3-0.2-0.10.4
Saline control response0.00.00.2-0.0-0.5-0.40.40.1-0.3-0.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.10.0-0.2-0.2-0.2
Bone: connectivity density0.81.23.8-1.50.50.5-0.51.0-0.5-0.90.9-0.90.9-0.9-1.0-1.01.0-1.0-1.01.51.92.01.6
Bone: cortical apparent density0.81.01.7-0.5-1.1-1.31.31.0-1.1-1.21.2-1.21.2-1.2-1.0-1.01.0-1.0-1.00.90.60.6-0.0
Bone: cortical area0.91.43.0-1.3-0.1-0.20.21.1-0.8-1.21.2-1.21.2-1.2-1.1-1.11.1-1.1-1.11.51.71.71.3
Bone: cortical porosity0.40.41.00.11.01.0-1.0-0.60.80.6-0.60.6-0.60.60.60.6-0.60.60.6-0.30.00.00.3
Bone: cortical porosity0.20.20.8-0.50.60.6-0.60.10.1-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.50.80.90.7
Bone: cortical thickness1.21.92.5-1.2-1.0-1.01.01.5-1.4-1.61.6-1.61.6-1.6-1.5-1.51.5-1.5-1.51.61.51.50.7
Bone: cortical thickness0.10.10.50.5-0.3-0.30.3-0.30.10.2-0.20.2-0.20.20.30.3-0.30.30.3-0.5-0.7-0.7-0.5
Bone: cortical tissue density0.50.71.3-0.4-0.9-1.11.10.8-0.9-0.90.9-0.90.9-0.9-0.8-0.80.8-0.8-0.80.80.50.5-0.1
Condit. Reinf. active minus inactive responses3.43.95.01.32.12.2-2.2-2.12.22.1-2.12.1-2.12.12.22.2-2.22.22.1-1.7-1.4-1.30.1
Condit. Reinf. active-inactive response ratio2.22.42.81.41.21.2-1.2-1.61.61.7-1.71.7-1.71.71.71.7-1.71.71.6-1.6-1.5-1.5-0.7
Condit. Reinf. active responses2.63.25.80.62.32.4-2.4-1.82.21.9-1.91.9-1.91.91.91.9-1.91.91.9-1.1-0.7-0.60.9
Condit. Reinf. inactive responses0.60.72.1-0.41.31.5-1.5-0.61.00.6-0.60.6-0.60.60.70.7-0.70.70.60.10.40.51.4
Incentive salience index mean1.61.93.70.31.91.9-1.9-1.41.71.4-1.41.4-1.41.41.51.5-1.51.51.4-0.8-0.4-0.40.8
Condit. Reinf. lever presses0.60.73.9-1.50.90.9-0.90.40.2-0.30.3-0.30.3-0.3-0.2-0.20.2-0.2-0.41.11.41.52.0
Condit. Reinf. active minus inactive responses2.73.34.12.01.21.2-1.2-1.91.71.9-1.91.9-1.91.91.91.9-1.91.91.9-2.0-1.9-1.9-1.3
Condit. Reinf. active-inactive response ratio0.70.82.51.4-0.4-0.40.4-0.60.30.7-0.70.7-0.70.70.70.7-0.70.70.6-1.2-1.5-1.5-1.6
Condit. Reinf. active responses2.12.93.51.51.71.7-1.7-1.81.91.8-1.81.8-1.81.81.91.9-1.91.91.8-1.7-1.4-1.3-0.5
Condit. Reinf. inactive responses0.91.12.50.41.51.6-1.6-1.11.31.0-1.01.0-1.01.01.11.1-1.11.11.1-0.6-0.3-0.30.5
Condit. Reinf. lever presses2.53.44.01.81.41.5-1.5-2.01.82.0-2.02.0-2.02.02.02.0-2.02.02.0-2.0-1.8-1.8-0.9
Condit. Reinf. lever reinforcers received1.72.42.91.41.31.4-1.4-1.71.61.7-1.71.7-1.71.71.71.7-1.71.71.7-1.6-1.5-1.4-0.6
Conditioned reinforcement - actives2.32.33.0-0.61.71.7-1.7-1.31.71.7-1.71.7-1.71.71.71.7-1.71.71.6-1.0-1.0-1.01.0
Conditioned reinforcement - inactives1.01.17.72.8-1.3-1.41.4-0.3-0.9-0.60.6-0.60.6-0.6-0.6-0.60.6-0.6-0.6-0.0-0.2-0.2-2.3
Conditioned locomotion7.18.610.62.13.03.0-3.0-3.03.23.2-3.23.2-3.23.23.23.2-3.23.22.9-2.7-2.2-2.2-0.6
Patch foraging indifference point 0 sec0.20.41.81.3-0.5-0.40.4-0.0-0.5-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.50.40.60.6-0.7
Patch foraging indifference point AUC1.01.21.4-1.21.01.0-1.0-0.51.21.2-1.21.2-1.21.21.21.2-1.21.21.1-0.9-1.0-1.00.9
Delay disc. indifference point, 0s delay8.18.812.1-3.2-2.0-2.02.03.0-2.8-3.13.1-3.13.1-3.1-3.1-3.13.1-3.1-3.13.53.43.32.4
Delay disc. indifference point, 16s delay0.10.10.30.1-0.3-0.30.30.5-0.4-0.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.50.30.40.4-0.2
Delay disc. indifference point, 2s delay6.06.68.1-2.9-2.1-2.02.02.7-2.6-2.72.7-2.72.7-2.7-2.7-2.72.7-2.7-2.72.82.52.51.8
Delay disc. indifference point, 24s delay0.50.51.9-1.1-0.7-0.60.61.4-0.8-0.70.7-0.70.7-0.7-0.8-0.80.8-0.8-0.80.40.40.40.2
Delay disc. indifference point, 4s delay1.51.52.6-1.4-0.6-0.50.51.5-1.1-1.31.3-1.31.3-1.3-1.3-1.31.3-1.3-1.31.41.61.61.1
Delay disc. indifference point, 8s delay0.90.91.50.5-1.2-1.21.20.7-1.1-1.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.00.50.40.4-1.1
Indifference point function ln k0.30.41.71.3-0.7-0.70.70.1-0.6-0.60.6-0.60.6-0.6-0.6-0.60.6-0.6-0.60.30.40.4-1.1
Indifference point function log k0.30.41.71.3-0.7-0.70.70.1-0.6-0.60.6-0.60.6-0.6-0.6-0.60.6-0.6-0.60.30.40.4-1.1
Patch foraging total patch changes 0 sec0.20.32.31.5-0.5-0.40.4-0.1-0.5-0.50.5-0.50.5-0.5-0.4-0.40.4-0.4-0.30.30.40.4-0.8
Patch foraging total patch changes 12 sec0.20.31.0-0.8-1.0-0.90.90.6-0.6-0.50.5-0.50.5-0.5-0.4-0.40.4-0.4-0.40.0-0.3-0.40.2
Patch foraging total patch changes 18 sec0.91.11.70.21.11.0-1.0-1.01.21.2-1.21.2-1.21.21.21.2-1.21.21.3-1.0-0.9-0.90.2
Patch foraging total patch changes 24 sec0.20.32.6-1.60.40.5-0.50.20.30.2-0.20.2-0.20.20.30.3-0.30.30.4-0.1-0.1-0.11.3
Patch foraging total patch changes 6 sec0.50.77.02.60.30.4-0.4-1.10.50.4-0.40.4-0.40.40.60.6-0.60.60.6-0.6-0.3-0.3-1.3
Patch foraging time to switch 0 sec1.82.74.2-0.7-1.1-1.01.01.4-1.6-1.91.9-1.91.9-1.9-1.8-1.81.8-1.8-1.72.02.02.00.6
Patch foraging water rate 0 sec0.30.51.90.7-0.4-0.40.4-0.30.20.5-0.50.5-0.50.50.60.6-0.60.60.4-1.1-1.3-1.4-1.1
Patch foraging water rate 12 sec0.61.03.3-0.8-1.7-1.81.81.0-1.2-0.80.8-0.80.8-0.8-0.8-0.80.8-0.8-0.80.2-0.5-0.6-0.4
Patch foraging water rate 18 sec1.11.55.61.4-0.8-0.70.7-0.70.30.8-0.80.8-0.80.81.01.0-1.01.00.8-1.8-2.3-2.4-1.8
Patch foraging water rate 24 sec1.62.212.43.3-1.8-1.81.8-0.5-0.60.1-0.10.1-0.10.10.10.1-0.10.10.0-1.4-1.9-1.9-3.5
Patch foraging water rate 6 sec1.01.53.71.8-0.1-0.10.1-1.10.71.1-1.11.1-1.11.11.11.1-1.11.11.0-1.7-1.9-1.9-1.9
Seeking ratio, delayed vs. immediate footshock3.94.56.81.72.52.6-2.6-2.32.52.3-2.32.3-2.32.32.22.2-2.22.22.1-1.7-1.1-1.0-0.1
Distance traveled before self-admin0.30.41.4-1.2-0.3-0.20.21.0-0.5-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.80.50.70.70.4
Distance traveled after self-admin0.70.81.30.81.11.1-1.1-0.81.00.9-0.90.9-0.90.91.01.0-1.01.00.8-1.0-0.4-0.4-0.4
Extensor digitorum longus weight3.513.722.7-1.8-4.7-4.84.84.0-4.4-3.93.9-3.93.9-3.9-3.9-3.93.9-3.9-4.02.61.81.6-1.3
Bone: elastic displacement0.20.30.40.20.60.6-0.6-0.50.60.6-0.60.6-0.60.60.50.5-0.50.50.5-0.4-0.2-0.2-0.1
Bone: elastic work0.20.30.7-0.6-0.1-0.10.10.6-0.4-0.60.6-0.60.6-0.6-0.6-0.60.6-0.6-0.60.70.80.80.3
Bone: endosteal estimation0.30.61.2-0.8-0.2-0.30.30.8-0.6-0.80.8-0.80.8-0.8-0.8-0.80.8-0.8-0.81.01.11.10.7
Bone: endosteal perimeter0.20.41.6-0.21.21.1-1.1-0.40.70.4-0.40.4-0.40.40.40.4-0.40.40.40.10.50.61.0
Epididymis fat weight0.20.51.10.40.30.3-0.3-0.70.60.8-0.80.8-0.80.80.80.8-0.80.80.7-1.0-1.0-1.0-0.4
Delta time in closed arm before/after self-admin0.70.62.30.2-1.5-1.41.40.5-0.8-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.3-0.6-1.1-1.2-1.2
Delta time in open arm before/after self-admin1.21.21.50.3-1.0-1.01.00.9-1.2-1.21.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.01.11.1-0.5
Diff in mean of infusions in LGA sessions1.41.62.20.41.21.2-1.2-1.21.41.4-1.41.4-1.41.41.41.4-1.41.41.5-1.2-1.0-1.0-0.0
Delay discount exponential model param1.92.02.71.01.21.2-1.2-1.61.51.5-1.51.5-1.51.51.51.5-1.51.51.6-1.3-1.4-1.4-0.3
Extinction: sum of active levers before priming1.71.73.11.00.60.5-0.5-1.31.21.4-1.41.4-1.41.41.41.4-1.41.41.3-1.5-1.8-1.8-0.8
Active lever presses in extinction session 62.62.63.50.11.91.8-1.8-1.41.91.8-1.81.8-1.81.81.81.8-1.81.81.7-1.4-1.1-1.10.5
Bone: final force1.52.43.7-1.6-0.7-0.70.71.6-1.3-1.71.7-1.71.7-1.7-1.6-1.61.6-1.6-1.61.91.91.91.3
Bone: final moment1.22.03.1-1.5-0.6-0.60.61.5-1.2-1.51.5-1.51.5-1.5-1.4-1.41.4-1.4-1.41.71.81.81.2
Food consumed during 24 hour testing period0.40.50.6-0.6-0.8-0.80.80.7-0.8-0.80.8-0.80.8-0.8-0.7-0.70.7-0.7-0.70.60.50.40.2
Glucose1.01.52.0-0.9-1.4-1.31.31.4-1.4-1.31.3-1.31.3-1.3-1.3-1.31.3-1.3-1.41.00.80.8-0.0
Heart weight0.40.61.20.10.50.4-0.4-0.60.70.9-0.90.9-0.90.90.80.8-0.80.80.8-1.0-1.1-1.1-0.2
Delay discount hyperbolic model param2.72.93.61.41.51.4-1.4-1.91.81.8-1.81.8-1.81.81.91.9-1.91.91.9-1.7-1.7-1.6-0.6
Intermittent access intake day 1-15 change7.27.212.13.52.32.2-2.2-3.12.72.8-2.82.8-2.82.82.82.8-2.82.82.7-2.6-2.3-2.2-1.7
Intermittent access intake escalation8.28.117.34.21.71.7-1.7-3.22.63.0-3.03.0-3.03.02.92.9-2.92.92.8-3.1-2.9-2.9-2.5
Intermittent access intake escalation 28.98.810.53.22.12.1-2.1-3.22.93.2-3.23.2-3.23.23.23.2-3.23.23.1-3.2-3.1-3.1-1.8
Intermitt. access day 1 inactive lever presses0.70.82.01.40.20.3-0.3-0.80.60.9-0.90.9-0.90.90.90.9-0.90.90.6-1.2-1.1-1.1-1.3
Intermitt. access day 15 inactive lever presses0.91.05.82.40.40.2-0.2-1.20.70.8-0.80.8-0.80.80.80.8-0.80.80.8-0.9-0.9-0.9-1.5
Intermitt. access escalation Index1.11.05.2-2.30.30.2-0.21.1-0.4-0.70.7-0.70.7-0.7-0.7-0.70.7-0.7-0.51.21.31.31.9
Intermittent access day 1 total infusions0.10.10.20.1-0.1-0.30.30.1-0.3-0.20.2-0.20.2-0.2-0.3-0.30.3-0.3-0.30.50.30.30.1
Intermittent access day 15 total infusions2.42.76.82.61.10.9-0.9-2.01.51.7-1.71.7-1.71.71.71.7-1.71.71.6-1.6-1.6-1.6-1.4
Intermittent access terminal intake (last 3 days)1.11.21.60.01.21.0-1.0-1.11.21.3-1.31.3-1.31.31.21.2-1.21.21.2-0.8-0.9-0.90.5
Intermittent access total infusions0.40.42.11.50.30.1-0.1-0.90.50.6-0.60.6-0.60.60.60.6-0.60.60.5-0.5-0.6-0.6-0.7
Intermittent access day 1 locomotion0.60.63.81.90.40.2-0.2-1.10.50.7-0.70.7-0.70.70.60.6-0.60.60.6-0.6-0.6-0.6-1.1
Intermittent access day 15 total locomotion4.24.511.83.41.71.5-1.5-2.52.02.2-2.22.2-2.22.22.22.2-2.22.21.9-2.1-1.8-1.7-1.8
Intermittent access total locomotion1.21.44.42.11.10.9-0.9-1.51.11.2-1.21.2-1.21.21.21.2-1.21.21.0-1.0-0.9-0.8-1.0
Intermittent access standard deviation3.33.54.51.41.61.5-1.5-1.91.92.1-2.12.1-2.12.12.12.1-2.12.11.8-1.9-1.8-1.8-0.6
Left kidney weight0.30.86.8-2.60.80.8-0.80.60.30.0-0.00.0-0.00.00.00.0-0.00.00.00.60.60.62.2
Right kidney weight1.23.35.10.02.32.3-2.3-1.62.11.9-1.91.9-1.91.92.02.0-2.02.01.9-1.4-1.1-1.00.7
Cocaine induced anxiety0.80.93.4-1.61.41.5-1.5-0.21.00.6-0.60.6-0.60.60.60.6-0.60.60.60.00.30.31.8
Post-drug Anxiety1.51.714.0-3.71.31.5-1.50.60.70.3-0.30.3-0.30.30.30.3-0.30.30.30.60.80.83.3
Baseline Anxiety0.10.10.4-0.0-0.2-0.20.2-0.10.10.2-0.20.2-0.20.20.30.3-0.30.30.3-0.4-0.6-0.6-0.2
Tail length3.19.411.93.22.72.7-2.7-3.43.23.3-3.33.3-3.33.33.33.3-3.33.33.3-3.0-2.7-2.6-1.6
Length with tail1.96.816.64.12.72.6-2.6-3.32.72.6-2.62.6-2.62.62.62.6-2.62.62.6-2.2-1.5-1.4-1.8
Length without tail0.20.44.62.10.70.6-0.6-0.80.30.0-0.00.0-0.00.0-0.0-0.00.0-0.00.10.20.80.9-0.7
Times rat made contact with spout0.20.20.60.3-0.8-0.70.70.3-0.5-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.3-0.1-0.3-0.4-0.7
Lifetime Intake0.10.10.1-0.10.30.1-0.1-0.40.30.4-0.40.4-0.40.40.30.3-0.30.30.3-0.0-0.3-0.30.4
Liver weight, left2.13.34.8-2.1-2.1-2.22.22.2-2.1-1.81.8-1.81.8-1.8-1.9-1.91.9-1.9-1.81.40.90.80.5
Liver weight, right1.52.63.3-1.3-1.6-1.61.61.7-1.8-1.71.7-1.71.7-1.7-1.8-1.81.8-1.8-1.81.51.31.30.6
Locomotor activity2.74.37.72.82.72.7-2.7-2.62.42.0-2.02.0-2.02.02.12.1-2.12.12.1-1.4-0.6-0.5-0.4
Locomotor testing distance1.72.84.41.92.12.1-2.1-2.01.91.7-1.71.7-1.71.71.71.7-1.71.71.7-1.2-0.7-0.6-0.2
Locomotor testing rearing0.10.10.2-0.10.10.0-0.0-0.20.20.3-0.30.3-0.30.30.30.3-0.30.30.4-0.3-0.5-0.50.2
Locomotion in novel chamber0.50.61.0-0.80.50.6-0.6-0.30.70.9-0.90.9-0.90.90.80.8-0.80.80.7-0.8-1.0-1.00.5
Locomotion in novel chamber post-restriction0.60.71.0-0.00.91.0-1.0-0.81.00.9-0.90.9-0.90.90.90.9-0.90.91.0-0.6-0.7-0.70.3
Fecal boli incidents, locomotor time 11.31.43.6-0.5-1.7-1.91.91.0-1.5-1.21.2-1.21.2-1.2-1.2-1.21.2-1.2-1.10.80.20.2-0.5
Change in fecal boli incidents, locomotor task0.50.52.8-1.11.11.1-1.1-0.30.60.3-0.30.3-0.30.30.30.3-0.30.30.40.40.60.71.7
Time >=10cm from walls, locomotor time 10.60.61.4-1.1-0.2-0.10.10.8-0.5-0.70.7-0.70.7-0.7-0.6-0.60.6-0.6-0.71.01.11.11.2
Bouts of movement, locomotor time 10.20.20.30.50.40.3-0.3-0.40.40.5-0.50.5-0.50.50.50.5-0.50.50.5-0.4-0.5-0.5-0.3
Total resting periods, locomotor time 10.20.20.30.40.60.4-0.4-0.50.50.5-0.50.5-0.50.50.60.6-0.60.60.5-0.4-0.4-0.3-0.1
Rest time, locomotor task time 10.20.20.5-0.40.60.5-0.5-0.30.50.4-0.40.4-0.40.40.50.5-0.50.50.4-0.0-0.1-0.10.7
Distance moved, locomotor task time 10.60.71.8-0.1-0.2-0.10.10.6-0.6-0.80.8-0.80.8-0.8-0.9-0.90.9-0.9-0.91.01.31.30.5
Vertical activity count, locomotor time 10.10.10.91.0-0.4-0.30.3-0.2-0.3-0.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.1-0.1-0.0-0.0-0.8
Time >=10cm from walls, locomotor time 20.70.81.7-0.0-1.3-1.31.30.9-1.1-0.90.9-0.90.9-0.9-0.8-0.80.8-0.8-1.00.50.30.2-0.6
Bouts of movement, locomotor time 20.30.31.1-0.21.01.0-1.0-0.40.70.4-0.40.4-0.40.40.40.4-0.40.40.30.00.40.50.8
Total resting periods, locomotor time 20.30.31.2-0.61.01.1-1.1-0.20.60.3-0.30.3-0.30.30.40.4-0.40.40.20.10.50.61.1
Rest time, locomotor task time 20.40.51.2-0.41.11.0-1.0-0.30.80.6-0.60.6-0.60.60.70.7-0.70.70.6-0.20.00.10.9
Distance moved, locomotor task time 20.60.71.61.0-1.3-1.21.20.5-1.0-0.80.8-0.80.8-0.8-0.8-0.80.8-0.8-0.80.20.00.0-1.3
Vertical activity count, locomotor time 20.60.72.00.8-1.4-1.41.40.3-0.9-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.50.0-0.4-0.4-1.3
Light reinforcement 14.98.911.73.43.13.2-3.2-3.43.33.1-3.13.1-3.13.13.13.1-3.13.13.2-2.6-2.0-1.9-1.2
Light reinforcement 21.82.48.22.91.51.5-1.5-2.01.61.5-1.51.5-1.51.51.51.5-1.51.51.6-1.3-0.9-0.8-1.4
Bone: marrow area0.30.61.1-0.8-0.2-0.30.30.8-0.6-0.80.8-0.80.8-0.8-0.8-0.80.8-0.8-0.81.01.11.10.7
Bone: maximum diameter0.50.92.8-0.01.71.6-1.6-0.81.20.7-0.70.7-0.70.70.80.8-0.80.80.80.00.50.51.2
Bone: maximum force1.42.43.2-1.4-0.9-1.01.01.6-1.4-1.71.7-1.71.7-1.7-1.6-1.61.6-1.6-1.61.81.81.81.0
Bone: maximum moment1.22.02.7-1.3-0.8-0.90.91.5-1.3-1.61.6-1.61.6-1.6-1.5-1.51.5-1.5-1.51.61.71.61.0
Mean time between licks in bursts4.05.66.62.42.12.0-2.0-2.62.52.5-2.52.5-2.52.52.62.6-2.62.62.6-2.4-2.2-2.2-1.3
Mean num. licks in bursts0.10.10.4-0.60.10.2-0.20.3-0.1-0.20.2-0.20.2-0.2-0.3-0.30.3-0.3-0.30.30.50.50.6
Cd content in liver0.20.20.2-0.4-0.3-0.30.30.5-0.5-0.50.5-0.50.5-0.5-0.5-0.50.5-0.5-0.50.50.50.50.1
Co content in liver0.80.92.41.60.50.5-0.5-1.00.80.9-0.90.9-0.90.90.90.9-0.90.90.7-1.1-0.9-0.9-1.2
Cu content in liver0.30.41.3-0.50.20.2-0.20.4-0.2-0.50.5-0.50.5-0.5-0.5-0.50.5-0.5-0.70.81.11.10.7
Fe content in liver0.10.10.40.2-0.2-0.20.2-0.20.10.2-0.20.2-0.20.20.20.2-0.20.20.3-0.4-0.6-0.6-0.5
K content in liver0.20.20.8-0.60.50.5-0.50.30.0-0.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.50.50.90.90.8
Mg content in liver0.40.41.8-1.20.70.6-0.60.50.0-0.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.60.71.11.11.3
Mn content in liver1.11.34.5-1.42.02.0-2.0-0.21.10.5-0.50.5-0.50.50.50.5-0.50.50.40.61.21.32.1
Na content in liver1.11.21.9-0.8-0.7-0.70.71.2-1.0-1.21.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.21.41.40.3
Rb content in liver0.91.13.0-1.70.10.0-0.01.1-0.6-0.90.9-0.90.9-0.9-0.9-0.90.9-0.9-1.01.31.51.51.4
Se content in liver0.10.10.30.00.50.5-0.5-0.40.50.4-0.40.4-0.40.40.40.4-0.40.40.3-0.2-0.1-0.10.4
Sr content in liver0.40.42.41.1-0.5-0.50.5-0.3-0.00.3-0.30.3-0.30.30.30.3-0.30.30.6-0.8-1.0-1.0-1.5
Zn content in liver3.03.36.12.20.70.6-0.6-1.81.51.9-1.91.9-1.91.91.91.9-1.91.91.6-2.3-2.5-2.5-1.8
Bone: minimum diameter0.10.20.8-0.50.40.3-0.30.3-0.0-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.30.70.90.90.9
Time in familiar zone, hab. session 12.12.02.41.41.21.2-1.2-1.61.41.5-1.51.5-1.51.51.51.5-1.51.51.6-1.5-1.3-1.3-0.7
Time in novel zone, hab. session 11.41.42.5-1.5-0.5-0.50.51.2-0.9-1.21.2-1.21.2-1.2-1.1-1.11.1-1.1-1.21.51.61.61.3
Total zone transitions, hab. session 10.60.82.7-0.31.61.6-1.6-0.71.10.7-0.70.7-0.70.70.80.8-0.80.80.7-0.10.40.51.2
Total locomotion distance, hab. session 10.91.34.4-0.82.02.1-2.1-0.61.20.6-0.60.6-0.60.60.60.6-0.60.60.60.41.01.12.0
Locomotion velocity, hab. session 11.01.54.6-0.42.12.1-2.1-0.91.41.0-1.01.0-1.01.01.01.0-1.01.01.0-0.10.50.61.6
Time in familiar zone, hab. session 26.46.68.02.42.12.1-2.1-2.82.62.8-2.82.8-2.82.82.72.7-2.72.72.8-2.7-2.6-2.5-1.3
Time in novel zone, hab. session 25.05.06.2-2.3-1.6-1.61.62.4-2.2-2.42.4-2.42.4-2.4-2.4-2.42.4-2.4-2.42.52.42.41.4
Total zone transitions, hab. session 20.91.13.3-1.60.20.4-0.40.8-0.4-0.90.9-0.90.9-0.9-0.8-0.80.8-0.8-0.81.41.71.71.8
Total locomotion distance, hab. session 20.50.72.5-0.21.41.6-1.6-0.71.00.7-0.70.7-0.70.70.70.7-0.70.70.7-0.10.30.41.1
Locomotion velocity, hab. session 20.60.82.8-0.51.51.7-1.7-0.61.00.6-0.60.6-0.60.60.60.6-0.60.60.60.10.60.71.5
Novel to familiar place preference ratio4.64.86.9-2.6-1.3-1.31.32.4-2.0-2.22.2-2.22.2-2.2-2.3-2.32.3-2.3-2.32.62.52.51.8
Novelty place preference3.03.05.0-2.2-0.9-0.90.91.9-1.5-1.71.7-1.71.7-1.7-1.8-1.81.8-1.8-1.92.12.12.11.6
Time in novel zone, NPP test3.23.35.1-2.2-1.0-1.01.02.0-1.7-1.81.8-1.81.8-1.8-1.9-1.91.9-1.9-2.02.12.12.11.6
Total zone transitions, NPP test0.20.20.8-0.70.20.3-0.30.3-0.1-0.40.4-0.40.4-0.4-0.3-0.30.3-0.3-0.30.60.80.80.9
Total locomotion distance, NPP test0.40.51.8-1.10.30.5-0.50.5-0.2-0.50.5-0.50.5-0.5-0.5-0.50.5-0.5-0.50.91.21.21.3
Locomotion velocity, NPP test0.20.31.5-0.90.60.7-0.70.20.1-0.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.20.60.91.01.2
Intraocular pressure0.30.42.1-0.6-0.5-0.40.4-0.00.10.5-0.50.5-0.50.50.40.4-0.40.40.6-0.8-1.4-1.4-0.1
Delta distance traveled before/after self-admin1.51.63.81.91.31.3-1.3-1.61.31.3-1.31.3-1.31.31.31.3-1.31.31.4-1.2-0.8-0.8-0.6
Delta ambulatory time before/after self-admin1.31.52.40.21.51.5-1.5-1.21.41.3-1.31.3-1.31.31.31.3-1.31.31.4-0.9-0.6-0.60.7
Parametrial fat weight0.71.35.32.30.80.7-0.7-1.51.01.1-1.11.1-1.11.11.01.0-1.01.01.0-1.1-1.0-0.9-1.2
Pavlov. Cond. lever latency0.30.41.71.0-0.5-0.50.5-0.40.10.3-0.30.3-0.30.30.40.4-0.40.40.4-0.8-1.1-1.1-1.3
Pavlov. Cond. magazine entry latency2.53.24.11.51.71.7-1.7-2.01.91.9-1.91.9-1.91.92.02.0-2.02.02.0-1.7-1.6-1.5-0.4
Pavlov. Cond. change in total contacts0.00.00.10.00.30.3-0.3-0.20.20.2-0.20.2-0.20.20.20.2-0.20.20.2-0.1-0.0-0.00.1
Pavlov. Cond. index score0.30.30.9-0.20.91.0-1.0-0.50.70.5-0.50.5-0.50.50.50.5-0.50.50.5-0.10.20.20.8
Pavlov. Cond. latency score0.30.41.3-0.41.11.1-1.1-0.40.70.4-0.40.4-0.40.40.40.4-0.40.40.40.20.50.51.1
Pavlov. Cond. lever contacts0.40.42.3-1.10.80.8-0.80.20.2-0.10.1-0.10.1-0.1-0.2-0.20.2-0.2-0.20.81.11.11.5
Pavlov. Cond. magazine entry number0.50.60.8-0.6-0.8-0.80.80.9-0.9-0.80.8-0.80.8-0.8-0.9-0.90.9-0.9-0.90.70.60.6-0.1
Pavlov. Cond. intertrial magazine entries0.30.41.00.9-0.2-0.10.1-0.60.30.4-0.40.4-0.40.40.60.6-0.60.60.6-0.8-1.0-1.0-0.8
Pavlov. Cond. lever-magazine prob. diff.0.50.61.40.11.21.2-1.2-0.81.00.8-0.80.8-0.80.80.80.8-0.80.80.8-0.3-0.1-0.00.7
Pavlov. Cond. response bias0.81.01.30.61.11.1-1.1-1.11.21.1-1.11.1-1.11.11.11.1-1.11.11.1-0.8-0.7-0.70.1
Pavlov. Cond. lever latency0.71.01.5-0.6-1.2-1.21.21.1-1.1-1.11.1-1.11.1-1.1-1.0-1.01.0-1.0-1.10.80.60.60.0
Pavlov. Cond. magazine entry latency0.40.51.10.31.01.0-1.0-0.70.80.8-0.80.8-0.80.80.70.7-0.70.70.7-0.5-0.2-0.20.3
Pavlov. Cond. change in total contacts0.81.21.50.81.11.1-1.1-1.11.11.2-1.21.2-1.21.21.11.1-1.11.11.1-1.1-0.8-0.8-0.4
Pavlov. Cond. index score0.91.11.50.81.21.2-1.2-1.11.21.2-1.21.2-1.21.21.11.1-1.11.11.1-1.0-0.7-0.7-0.2
Pavlov. Cond. latency score0.80.91.50.61.21.2-1.2-1.01.11.1-1.11.1-1.11.11.01.0-1.01.01.0-0.8-0.5-0.40.0
Pavlov. Cond. lever contacts0.81.11.40.81.01.0-1.0-1.11.11.2-1.21.2-1.21.21.11.1-1.11.11.1-1.1-0.9-0.9-0.4
Pavlov. Cond. magazine entry number0.70.91.7-0.5-1.3-1.31.30.9-1.1-1.01.0-1.01.0-1.0-1.0-1.01.0-1.0-0.90.70.30.3-0.2
Pavlov. Cond. intertrial magazine entries0.30.41.40.2-1.2-1.11.10.4-0.7-0.70.7-0.70.7-0.7-0.4-0.40.4-0.4-0.40.2-0.2-0.2-0.6
Pavlov. Cond. lever-magazine prob. diff.0.91.11.60.71.31.3-1.3-1.11.21.2-1.21.2-1.21.21.11.1-1.11.11.1-0.9-0.6-0.5-0.1
Pavlov. Cond. response bias1.92.53.21.31.51.5-1.5-1.71.71.8-1.81.8-1.81.81.71.7-1.71.71.7-1.6-1.4-1.3-0.6
Time in closed arm before self-admin1.11.22.6-0.0-0.5-0.50.50.6-1.0-1.21.2-1.21.2-1.2-1.3-1.31.3-1.3-1.11.51.61.60.5
Time in closed arm after self-admin0.00.00.4-0.6-0.00.1-0.10.00.10.0-0.00.0-0.00.00.10.1-0.10.10.2-0.1-0.2-0.20.5
Time in open arm before self-admin1.11.21.60.60.90.9-0.9-0.91.11.2-1.21.2-1.21.21.21.2-1.21.21.0-1.3-1.1-1.1-0.5
Time in open arm after self-admin0.70.72.21.2-1.0-1.11.10.5-0.9-0.80.8-0.80.8-0.8-0.8-0.80.8-0.8-0.90.40.40.4-1.5
Bone: periosteal estimation0.61.33.2-1.3-0.0-0.10.11.1-0.7-1.21.2-1.21.2-1.2-1.1-1.11.1-1.1-1.11.51.81.81.4
Bone: periosteal perimeter0.20.41.6-0.61.00.9-0.90.10.3-0.10.1-0.10.1-0.1-0.0-0.00.0-0.0-0.00.71.11.11.3
Bone: post-yield work0.50.71.0-0.4-0.9-1.01.00.9-0.9-1.01.0-1.01.0-1.0-0.8-0.80.8-0.8-0.80.80.60.50.1
Progressive ratio test 1 active lever presses0.10.10.40.2-0.4-0.70.70.0-0.3-0.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.20.2-0.2-0.2-0.3
Progressive ratio test 1 breakpoint0.10.10.4-0.4-0.4-0.70.70.3-0.4-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.30.3-0.0-0.00.1
Progressive ratio test 1 inactive lever presses0.00.00.40.60.10.0-0.0-0.30.10.1-0.10.1-0.10.10.10.1-0.10.10.10.0-0.0-0.0-0.2
Progressive ratio test 2 active lever presses0.30.30.7-0.00.30.2-0.2-0.50.50.7-0.70.7-0.70.70.70.7-0.70.70.5-0.6-0.8-0.8-0.0
Progressive ratio test 2 breakpoint0.30.40.5-0.70.60.6-0.6-0.30.60.7-0.70.7-0.70.70.70.7-0.70.70.5-0.4-0.5-0.50.7
Progressive ratio test 2 inactive lever presses0.00.10.10.00.30.2-0.2-0.40.30.3-0.30.3-0.30.30.20.2-0.20.20.1-0.0-0.1-0.10.3
Incentive Sensitization - Responses0.50.50.9-0.90.30.4-0.4-0.20.60.8-0.80.8-0.80.80.80.8-0.80.80.5-0.7-0.9-0.90.5
Incentive Sensitization - Breakpoint0.60.62.3-1.50.50.6-0.6-0.10.70.8-0.80.8-0.80.80.80.8-0.80.80.5-0.6-0.8-0.80.9
Sum of active levers in priming session hrs 5-60.00.00.10.2-0.1-0.20.2-0.00.00.1-0.10.1-0.10.10.10.1-0.10.10.0-0.1-0.2-0.2-0.3
Progressive ratio0.30.33.1-1.7-0.7-0.60.60.9-0.5-0.20.2-0.20.2-0.2-0.3-0.30.3-0.3-0.40.1-0.2-0.20.6
Food seeking constrained by brief footshock0.10.10.7-0.80.30.4-0.4-0.00.30.2-0.20.2-0.20.20.30.3-0.30.30.2-0.1-0.2-0.20.5
Seeking ratio, punishment vs. effort0.20.32.81.70.50.4-0.4-0.80.40.1-0.10.1-0.10.10.30.3-0.30.30.4-0.10.00.1-0.8
Retroperitoneal fat weight0.51.56.32.5-1.5-1.71.70.2-1.2-1.11.1-1.11.1-1.1-1.0-1.01.0-1.0-1.00.30.30.3-2.1
Reaction time number correct0.40.51.9-0.7-1.4-1.31.30.7-0.9-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.50.1-0.5-0.5-0.3
Reaction time mean minus median0.81.01.5-0.81.21.2-1.2-0.61.11.0-1.01.0-1.01.01.11.1-1.11.10.9-0.7-0.6-0.61.0
Reaction time mean minus median AUC0.70.95.6-2.40.90.9-0.90.70.2-0.10.1-0.10.1-0.1-0.2-0.20.2-0.2-0.30.81.11.12.3
Reaction time num false alarms0.10.10.7-0.8-0.3-0.40.40.4-0.2-0.10.1-0.10.1-0.1-0.0-0.00.0-0.0-0.1-0.0-0.3-0.30.2
Reaction time num false alarms AUC0.10.21.2-1.1-0.6-0.60.60.5-0.3-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.5-0.60.1
Reaction time trials correct on left0.40.51.9-0.7-1.4-1.31.30.7-0.9-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.50.1-0.5-0.5-0.3
Reaction time trials on left0.40.51.8-0.8-1.3-1.31.30.8-0.9-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.60.2-0.4-0.5-0.2
Reaction time mean0.30.53.0-1.60.60.5-0.50.60.1-0.30.3-0.30.3-0.3-0.2-0.20.2-0.2-0.20.60.90.91.7
Reaction time mean AUC0.30.41.9-1.10.40.4-0.40.5-0.1-0.40.4-0.40.4-0.4-0.3-0.30.3-0.3-0.30.70.90.91.4
Median of all reaction times0.60.82.2-1.4-0.0-0.00.01.0-0.5-0.80.8-0.80.8-0.8-0.7-0.70.7-0.7-0.71.11.21.21.5
Reaction time omissions0.20.30.6-0.00.80.7-0.7-0.40.60.5-0.50.5-0.50.50.60.6-0.60.60.5-0.3-0.2-0.10.3
Reaction time false alarm rate0.10.11.1-1.00.10.0-0.00.4-0.0-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.20.10.10.6
Reaction time premature initiation rate1.82.411.13.30.50.6-0.6-1.81.11.3-1.31.3-1.31.31.41.4-1.41.41.4-1.8-1.5-1.5-2.2
Reaction time premature initiations1.52.210.03.2-0.2-0.10.1-1.50.81.1-1.11.1-1.11.11.21.2-1.21.21.2-1.8-1.9-1.9-2.5
Std. dev. reaction times0.50.63.7-1.91.01.0-1.00.10.70.5-0.50.5-0.50.50.50.5-0.50.50.4-0.00.10.11.8
Reaction time trials completed0.40.51.8-0.8-1.3-1.31.30.8-0.9-0.60.6-0.60.6-0.6-0.5-0.50.5-0.5-0.60.2-0.4-0.5-0.2
Reaction time trials AUC0.40.52.0-0.6-1.4-1.41.40.7-0.8-0.50.5-0.50.5-0.5-0.4-0.40.4-0.4-0.5-0.0-0.6-0.7-0.4
Run reversals in cocaine runway, females0.70.73.2-1.81.11.1-1.1-0.10.80.5-0.50.5-0.50.50.60.6-0.60.60.5-0.10.10.11.7
Run reversals in cocaine runway, males1.01.02.1-1.11.51.5-1.5-0.61.20.9-0.90.9-0.90.91.01.0-1.01.01.0-0.3-0.2-0.21.3
Latency to leave start box in cocaine runway0.80.82.60.51.61.5-1.5-0.91.10.8-0.80.8-0.80.80.80.8-0.80.80.6-0.20.30.40.7
Latency to leave start box in cocaine runway, F0.80.94.9-1.71.00.8-0.80.40.2-0.40.4-0.40.4-0.4-0.3-0.30.3-0.3-0.51.21.51.52.2
Latency to leave start box in cocaine runway, M3.63.45.22.01.21.2-1.2-1.81.72.0-2.02.0-2.02.01.91.9-1.91.91.9-2.3-2.0-2.0-1.3
Std. dev. time between licks in bursts0.60.71.80.01.31.3-1.3-0.81.00.7-0.70.7-0.70.70.80.8-0.80.80.8-0.20.20.20.8
Total sessions with >9 infusions0.80.98.8-3.00.70.5-0.50.60.1-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.80.60.62.5
Short access day 1 total inactive lever presses0.00.10.2-0.40.20.1-0.1-0.20.20.2-0.20.2-0.20.20.20.2-0.20.20.3-0.0-0.2-0.20.4
Short access day 10 total inactive lever presses0.50.53.71.9-0.1-0.20.2-0.60.20.4-0.40.4-0.40.40.40.4-0.40.40.2-0.8-0.7-0.7-1.6
Short access day 1 total infusions0.50.64.2-2.00.90.7-0.70.10.40.2-0.20.2-0.20.20.10.1-0.10.10.20.60.50.52.0
Short access day 10 total infusions0.20.33.0-1.70.1-0.00.00.20.10.2-0.20.2-0.20.20.20.2-0.20.20.10.2-0.2-0.21.4
Short access total infusions0.80.910.2-3.20.50.3-0.30.70.10.0-0.00.0-0.00.0-0.0-0.00.0-0.0-0.10.70.30.32.6
Short access day 1 locomotion1.01.16.42.51.20.9-0.9-1.61.00.9-0.90.9-0.90.90.90.9-0.90.90.9-0.5-0.2-0.2-0.9
Short access day 10 total locomotion4.65.29.53.11.81.7-1.7-2.82.32.4-2.42.4-2.42.42.42.4-2.42.42.3-2.2-2.0-2.0-1.5
Short access total locomotion0.90.91.50.71.21.0-1.0-1.11.11.1-1.11.1-1.11.11.01.0-1.01.01.0-0.5-0.6-0.50.2
One hour access (0.3 mA shock)0.20.31.31.1-0.5-0.70.7-0.1-0.5-0.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.60.40.20.2-0.7
Compulsive drug intake1.11.11.50.3-0.9-0.70.70.8-1.1-1.21.2-1.21.2-1.2-1.2-1.21.2-1.2-1.20.91.11.1-0.4
One hour access (shock baseline)0.30.42.81.7-0.1-0.30.3-0.70.20.4-0.40.4-0.40.40.40.4-0.40.40.3-0.5-0.7-0.7-1.1
Social response proportion0.50.51.2-0.41.01.1-1.1-0.50.80.7-0.70.7-0.70.70.60.6-0.60.60.7-0.3-0.1-0.10.6
Social responses5.87.413.40.53.73.6-3.6-2.63.23.0-3.03.0-3.03.02.82.8-2.82.82.8-1.9-1.3-1.21.0
Social time0.50.71.30.2-1.1-1.11.10.6-1.0-0.90.9-0.90.9-0.9-0.9-0.90.9-0.9-0.80.60.40.4-0.5
Soleus weight7.722.628.5-3.4-4.9-5.05.05.2-5.3-5.25.2-5.25.2-5.2-5.2-5.25.2-5.2-5.24.23.53.40.2
Bone: stiffness3.04.86.1-1.8-1.8-1.81.82.4-2.2-2.52.5-2.52.5-2.5-2.3-2.32.3-2.3-2.32.32.12.10.8
Tibialis anterior weight0.93.04.4-1.3-1.7-1.71.72.1-2.0-1.81.8-1.81.8-1.8-1.9-1.91.9-1.9-2.11.51.41.3-0.1
Time to tail flick, vehicle, before self-admin0.90.94.7-2.01.41.4-1.4-0.00.80.5-0.50.5-0.50.50.40.4-0.40.40.30.30.50.62.2
Time to tail flick, vehicle, after self-admin0.30.31.6-1.2-0.1-0.10.10.00.20.4-0.40.4-0.40.40.40.4-0.40.40.6-0.6-1.0-1.10.3
Time to tail flick, test, before self-admin1.51.412.7-3.61.11.0-1.00.50.40.1-0.10.1-0.10.10.00.0-0.00.00.30.90.70.73.2
Time to tail flick, test, after self-admin0.60.64.8-2.20.90.8-0.80.20.50.3-0.30.3-0.30.30.30.3-0.30.30.30.30.30.31.9
Delta time to tail flick, vehicle, before/after SA0.50.51.8-0.1-1.3-1.31.30.4-0.7-0.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.2-0.2-0.8-0.9-1.0
Delta time to tail flick, test, before/after SA0.70.74.32.1-0.1-0.10.1-0.80.30.5-0.50.5-0.50.50.50.5-0.50.50.4-1.0-0.9-0.9-1.7
Tibia length0.92.63.41.81.41.3-1.3-1.81.61.8-1.81.8-1.81.81.71.7-1.71.71.6-1.6-1.4-1.3-0.9
Ambulatory time before self-admin0.20.20.5-0.6-0.3-0.30.30.7-0.5-0.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.70.30.50.5-0.0
Ambulatory time after self-admin0.40.50.70.50.80.8-0.8-0.50.80.7-0.70.7-0.70.70.80.8-0.80.80.5-0.7-0.3-0.3-0.3
Bone: tissue strength1.71.72.1-1.0-1.1-1.21.21.4-1.3-1.51.5-1.51.5-1.5-1.4-1.41.4-1.4-1.41.31.21.10.5
Total heroin consumption1.72.02.9-1.21.71.6-1.6-0.91.61.5-1.51.5-1.51.51.51.5-1.51.51.4-1.0-0.9-0.91.2
Bone: trabecular number0.60.93.2-0.41.81.8-1.8-0.61.00.7-0.70.7-0.70.70.60.6-0.60.60.60.10.70.81.3
Bone: trabecular spacing0.71.03.51.0-1.7-1.71.70.1-0.7-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.1-0.9-1.5-1.6-1.9
Bone: trabecular thickness1.72.07.4-1.91.61.5-1.50.70.1-0.70.7-0.70.7-0.7-0.7-0.70.7-0.7-0.71.82.62.72.6
Bone: trabecular tissue density1.52.25.3-0.3-2.2-2.32.31.4-1.7-1.61.6-1.61.6-1.6-1.4-1.41.4-1.4-1.40.90.20.2-0.9
Water consumed over 24 hours0.81.01.9-1.3-0.3-0.30.31.0-0.8-1.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.01.31.41.41.2
Number of responses in last shaping day0.20.20.40.20.50.4-0.4-0.60.50.4-0.40.4-0.40.40.40.4-0.40.40.3-0.2-0.2-0.20.3