Ypel5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Ypel5 0.16 0.1 0.0e+00 0.16 0.16 0.15 0.16 3.3e-17 1.4e-17 8.4e-17 6.7e-18
2 NAcc alternative TSS XM_039111907.1 0.02 0.01 7.8e-03 0.01 0.01 0 0.01 9.0e-03 3.5e-02 1.8e-01 3.4e-02
3 NAcc mRNA stability Ypel5 0.04 0.03 5.6e-06 0.04 0.05 0.05 0.04 1.9e-05 2.1e-06 3.3e-06 7.3e-06
4 Liver isoform ratio XM_039111905.1 0.14 0.09 0.0e+00 0.14 0.16 0.17 0.16 1.4e-15 2.4e-17 3.0e-18 1.5e-17
5 Liver intron excision ratio chr6_22660590_22671605 0.07 0.04 5.5e-11 0.1 0.1 0.1 0.1 2.6e-11 3.1e-11 4.0e-11 1.1e-11
6 Liver isoform ratio XM_008764508.2 0.03 0.02 2.9e-04 0.03 0.03 0.03 0.03 7.0e-04 2.6e-04 5.7e-04 4.7e-04
7 IL mRNA stability Ypel5 0.14 0.12 7.5e-03 0.04 0.03 0.04 0.04 4.7e-02 6.0e-02 3.9e-02 3.0e-02
8 Liver mRNA stability Ypel5 0.42 0.15 0.0e+00 0.46 0.47 0.46 0.46 2.8e-57 6.6e-58 2.7e-57 2.2e-56
9 Adipose mRNA stability Ypel5 0.28 0.18 0.0e+00 0.26 0.25 0.25 0.27 4.5e-29 5.1e-28 1.7e-27 6.9e-30
10 Liver gene expression Ypel5 0.25 0.12 0.0e+00 0.3 0.31 0.31 0.31 5.6e-34 1.6e-34 1.5e-34 7.8e-35
11 pVTA mRNA stability Ypel5 0.06 0.04 2.7e-03 0.03 0.04 0.01 0.02 2.1e-02 1.1e-02 6.9e-02 6.4e-02
12 Liver alternative TSS XM_039111906.1 0.06 0.03 1.5e-08 0.06 0.08 0.07 0.06 9.2e-08 5.2e-09 1.8e-08 9.0e-08
13 Liver intron excision ratio chr6_22660590_22667194 0.04 0.03 3.8e-06 0.05 0.05 0.05 0.05 5.2e-06 2.5e-06 6.0e-06 3.3e-06
14 Liver isoform ratio NM_001035221.1 0.09 0.05 9.4e-16 0.14 0.14 0.14 0.15 1.4e-15 8.5e-16 1.5e-15 6.8e-16
15 Brain mRNA stability Ypel5 0.07 0.05 8.6e-06 0.05 0.04 0.05 0.05 2.0e-05 8.0e-05 2.2e-05 2.6e-05
16 Liver intron excision ratio chr6_22667280_22668285 0.04 0.03 2.9e-05 0.04 0.04 0.03 0.04 7.1e-05 2.4e-05 1.1e-04 8.7e-05
17 PL mRNA stability Ypel5 0.03 0.02 1.7e-04 0.04 0.04 0.03 0.03 6.1e-05 7.3e-05 1.3e-04 1.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.30.57.22.7-0.6-0.8-0.3-0.30.4-0.4-0.20.20.0-0.2-0.10.1-0.30.20.2-0.2
Area under the delay curve0.30.31.01.0-0.3-0.5-0.4-0.50.7-0.3-0.6-0.20.5-0.6-0.60.6-0.70.6-0.50.6
BMI with tail0.00.22.0-1.40.20.30.10.1-0.10.1-0.0-0.50.1-0.1-0.10.2-0.10.1-0.30.2
BMI without tail0.20.31.2-0.3-0.5-0.4-0.6-0.50.5-0.7-0.5-1.10.5-0.5-0.60.6-0.60.5-0.60.6
Body weight0.31.03.1-1.8-0.5-0.3-0.9-0.50.8-0.6-1.0-1.20.8-1.0-1.11.1-1.11.0-1.41.3
Weight adjusted by age0.10.10.4-0.30.60.00.10.2-0.1-0.30.2-0.5-0.2-0.10.0-0.0-0.1-0.1-0.00.3
Bone surface0.20.33.21.8-0.7-0.7-0.3-0.20.4-0.4-0.20.30.1-0.3-0.10.1-0.30.20.0-0.1
Bone volume0.20.33.81.9-0.6-0.6-0.2-0.20.2-0.3-0.10.3-0.0-0.10.0-0.0-0.10.10.2-0.4
Breakpoint value in progressive ratio session0.91.01.70.7-0.5-1.1-0.8-1.30.9-0.9-0.9-1.01.3-1.1-0.80.9-1.11.0-0.91.2
Number of licking bursts1.41.62.20.7-1.5-1.1-1.4-1.21.4-0.8-1.5-1.11.3-1.3-1.51.4-1.21.4-1.41.2
Context. condit. distance diff. score0.10.10.2-0.5-0.20.0-0.3-0.20.1-0.0-0.20.10.3-0.3-0.20.3-0.30.3-0.30.5
Locomotion velocity, session 10.30.30.5-0.00.60.20.60.7-0.60.10.60.2-0.70.50.7-0.70.5-0.50.7-0.7
Locomotion distance, session 10.10.22.11.50.1-0.10.20.30.10.00.20.0-0.50.20.1-0.20.2-0.30.4-0.4
Locomotion velocity, session 20.10.10.30.40.10.20.30.5-0.20.30.30.3-0.50.30.3-0.30.3-0.30.4-0.4
Locomotion distance, session 20.10.10.50.70.20.20.30.3-0.20.30.30.2-0.40.40.3-0.40.3-0.40.4-0.5
Locomotion velocity, session 30.40.51.91.4-0.5-0.8-0.6-0.70.6-0.7-0.5-0.70.6-0.6-0.50.5-0.70.6-0.40.6
Locomotion distance, session 32.83.03.91.7-1.8-1.7-1.8-2.01.8-1.4-1.8-1.41.9-1.7-1.81.8-1.71.8-1.71.5
Stereotopy head waving bouts, day 30.81.01.51.2-0.8-1.2-0.9-1.11.0-1.0-1.0-0.81.0-1.0-0.91.0-1.11.0-0.91.0
Stereotopy head waving duration, day 30.00.00.10.30.2-0.10.20.2-0.1-0.20.2-0.1-0.20.10.2-0.20.0-0.10.2-0.1
Locomotion velocity, session 72.02.23.81.7-1.4-1.4-1.5-1.41.6-1.4-1.5-1.91.3-1.4-1.61.5-1.51.4-1.41.3
Locomotion distance, session 70.10.10.40.2-0.70.0-0.5-0.20.40.1-0.4-0.20.2-0.2-0.60.4-0.20.2-0.40.2
Stereotopy head waving bouts, day 70.00.00.20.20.00.00.20.1-0.10.20.10.4-0.10.10.2-0.10.2-0.10.2-0.3
Stereotopy head waving duration, day 70.10.11.31.1-0.3-0.3-0.1-0.00.1-0.2-0.00.2-0.1-0.00.1-0.10.1-0.10.2-0.2
Locomotion velocity, session 80.10.20.70.9-0.4-0.6-0.4-0.20.3-0.7-0.2-0.50.2-0.3-0.20.2-0.40.3-0.10.3
Locomotion distance, session 80.20.30.50.7-0.5-0.3-0.6-0.60.6-0.1-0.5-0.20.6-0.5-0.60.6-0.60.5-0.50.6
Degree of sensitization distance1.31.32.0-1.41.01.41.01.4-1.01.31.01.0-1.31.10.9-1.01.1-1.20.9-1.0
Degree of sensitization stereotypy0.00.00.20.1-0.10.10.00.00.10.4-0.10.4-0.10.1-0.10.00.2-0.10.0-0.3
Conditioned locomotion0.10.12.01.40.2-0.10.0-0.10.30.1-0.10.0-0.0-0.0-0.20.0-0.2-0.00.10.1
Cocaine response after cond. corrected0.20.22.11.40.2-0.10.40.1-0.10.20.20.3-0.30.30.2-0.40.3-0.30.5-0.7
Cocaine response after cond. not corrected0.10.22.31.50.1-0.40.1-0.20.2-0.2-0.0-0.30.00.0-0.0-0.1-0.10.00.2-0.2
Cocaine response before conditioning1.21.52.40.6-0.8-1.2-1.2-1.31.1-1.4-1.0-1.51.3-1.3-1.11.2-1.41.2-1.21.5
Saline control response2.73.55.01.9-2.2-2.1-2.1-1.91.8-2.2-1.7-1.91.8-1.9-1.71.7-1.81.7-1.71.7
Bone: connectivity density0.30.56.12.5-0.6-0.7-0.4-0.20.5-0.4-0.20.2-0.0-0.3-0.20.1-0.30.10.1-0.0
Bone: cortical apparent density0.00.00.30.10.2-0.30.2-0.1-0.1-0.50.0-0.50.1-0.10.2-0.1-0.10.10.1-0.1
Bone: cortical area0.20.30.50.5-0.5-0.6-0.4-0.70.7-0.4-0.7-0.30.7-0.6-0.60.6-0.50.5-0.60.2
Bone: cortical porosity2.42.64.40.91.31.51.61.5-1.21.91.52.1-1.71.81.4-1.61.7-1.71.8-2.0
Bone: cortical porosity2.32.54.70.81.21.41.51.4-1.21.91.42.2-1.71.71.4-1.61.7-1.71.8-1.9
Bone: cortical thickness0.10.20.5-0.50.40.40.60.2-0.30.60.20.5-0.10.40.3-0.30.5-0.40.3-0.7
Bone: cortical thickness0.20.20.60.50.50.50.60.3-0.20.80.40.5-0.30.60.3-0.40.5-0.50.5-0.6
Bone: cortical tissue density0.00.10.2-0.00.3-0.20.3-0.0-0.2-0.40.2-0.40.00.00.3-0.20.00.00.2-0.2
Condit. Reinf. active minus inactive responses0.10.10.4-0.4-0.2-0.1-0.2-0.00.2-0.2-0.2-0.70.1-0.1-0.30.2-0.20.2-0.30.2
Condit. Reinf. active-inactive response ratio0.20.20.70.3-0.6-0.5-0.6-0.40.3-0.8-0.3-0.80.4-0.4-0.30.3-0.50.4-0.30.5
Condit. Reinf. active responses0.20.30.60.5-0.5-0.4-0.6-0.50.7-0.3-0.6-0.80.4-0.4-0.80.6-0.40.4-0.60.4
Condit. Reinf. inactive responses0.10.10.50.40.40.40.40.20.00.70.10.2-0.30.4-0.0-0.20.4-0.40.2-0.5
Incentive salience index mean0.40.40.90.9-0.8-0.6-0.7-0.50.8-0.6-0.7-1.00.5-0.5-0.80.6-0.60.5-0.60.5
Condit. Reinf. lever presses0.50.63.82.0-0.8-0.7-0.7-0.71.0-0.4-0.7-0.70.5-0.5-0.90.6-0.50.4-0.50.4
Condit. Reinf. active minus inactive responses0.50.61.11.1-0.7-0.6-0.7-0.81.0-0.2-0.9-0.50.7-0.6-1.00.8-0.60.6-0.80.6
Condit. Reinf. active-inactive response ratio0.20.20.40.7-0.2-0.3-0.2-0.40.60.0-0.5-0.40.4-0.2-0.60.5-0.20.3-0.40.2
Condit. Reinf. active responses0.20.30.60.7-0.8-0.4-0.7-0.60.7-0.3-0.6-0.40.6-0.5-0.70.6-0.50.4-0.60.5
Condit. Reinf. inactive responses0.10.20.60.4-0.8-0.2-0.6-0.40.3-0.3-0.3-0.30.3-0.3-0.40.3-0.30.2-0.30.4
Condit. Reinf. lever presses0.30.40.60.7-0.8-0.5-0.7-0.60.7-0.4-0.6-0.70.6-0.5-0.70.6-0.50.4-0.60.5
Condit. Reinf. lever reinforcers received0.20.20.40.5-0.6-0.3-0.6-0.50.6-0.2-0.5-0.30.5-0.4-0.60.5-0.40.3-0.50.4
Conditioned reinforcement - actives1.01.02.10.7-1.1-1.2-1.0-1.10.8-1.3-0.9-1.41.1-1.0-0.80.9-0.90.9-0.90.6
Conditioned reinforcement - inactives2.12.45.61.3-1.6-1.9-1.5-1.61.3-2.1-1.4-2.41.5-1.5-1.21.3-1.41.4-1.31.0
Conditioned locomotion0.91.12.70.1-0.5-1.3-0.8-1.10.7-1.5-0.8-1.71.1-1.1-0.60.8-1.21.1-0.91.1
Patch foraging indifference point 0 sec0.10.20.70.8-0.8-0.5-0.4-0.70.4-0.3-0.40.10.6-0.4-0.30.3-0.40.4-0.3-0.1
Patch foraging indifference point AUC1.82.13.11.4-1.7-1.6-1.6-1.31.4-1.7-1.3-1.61.2-1.4-1.41.3-1.41.3-1.31.4
Delay disc. indifference point, 0s delay1.71.92.6-1.01.21.61.21.6-1.31.51.41.5-1.61.51.2-1.31.3-1.51.3-1.0
Delay disc. indifference point, 16s delay0.30.32.51.6-0.5-0.6-0.5-0.40.6-0.3-0.4-0.10.3-0.4-0.50.4-0.50.3-0.30.4
Delay disc. indifference point, 2s delay0.70.71.3-0.31.10.90.91.0-0.80.80.90.8-1.10.90.8-0.90.7-0.90.9-0.4
Delay disc. indifference point, 24s delay3.63.56.92.6-1.7-1.9-1.8-1.92.1-1.4-1.9-1.31.8-1.9-1.91.9-2.01.9-1.71.7
Delay disc. indifference point, 4s delay0.60.71.10.30.80.70.90.7-0.80.50.90.6-0.90.90.9-1.00.7-0.91.0-0.9
Delay disc. indifference point, 8s delay1.21.21.81.3-0.8-1.0-1.0-1.21.3-0.6-1.2-0.71.1-1.2-1.31.2-1.31.3-1.21.0
Indifference point function ln k0.91.32.0-0.41.31.01.40.9-1.01.31.01.3-0.91.11.1-1.11.1-1.01.2-1.4
Indifference point function log k0.91.32.0-0.41.31.01.40.9-1.01.31.01.3-0.91.11.1-1.11.1-1.01.2-1.4
Patch foraging total patch changes 0 sec0.20.31.00.8-1.0-0.5-0.6-0.80.5-0.3-0.5-0.10.7-0.5-0.50.5-0.50.4-0.40.1
Patch foraging total patch changes 12 sec0.00.00.2-0.1-0.30.3-0.10.4-0.20.00.20.1-0.40.10.1-0.20.1-0.20.2-0.2
Patch foraging total patch changes 18 sec1.62.13.91.2-2.0-1.5-1.7-1.31.3-1.7-1.4-1.01.3-1.5-1.31.4-1.51.4-1.41.4
Patch foraging total patch changes 24 sec0.00.00.2-0.5-0.00.0-0.2-0.0-0.0-0.1-0.00.20.1-0.2-0.00.1-0.30.1-0.20.3
Patch foraging total patch changes 6 sec0.30.50.70.8-0.8-0.6-0.7-0.80.8-0.5-0.7-0.50.7-0.7-0.80.7-0.70.7-0.70.5
Patch foraging time to switch 0 sec0.40.60.90.6-0.7-0.7-0.8-0.70.8-0.5-0.8-0.40.7-0.8-0.90.9-0.80.8-0.90.9
Patch foraging water rate 0 sec0.71.11.5-0.61.21.01.20.9-1.11.01.10.8-0.91.11.1-1.11.0-1.11.1-1.1
Patch foraging water rate 12 sec3.96.08.9-2.33.02.62.82.4-2.52.32.51.7-2.42.52.4-2.52.5-2.42.4-2.4
Patch foraging water rate 18 sec0.60.82.3-1.41.51.11.10.8-0.81.00.80.2-0.70.90.7-0.80.7-0.80.7-0.7
Patch foraging water rate 24 sec1.01.44.2-2.11.61.51.21.3-1.11.31.10.7-1.11.10.9-0.91.0-1.00.8-0.8
Patch foraging water rate 6 sec1.72.63.3-1.61.61.81.61.8-1.61.71.61.3-1.81.61.5-1.61.6-1.71.5-1.5
Seeking ratio, delayed vs. immediate footshock0.40.41.3-0.3-1.0-0.8-0.6-0.50.3-1.1-0.4-1.00.6-0.6-0.30.5-0.60.6-0.50.5
Distance traveled before self-admin2.32.43.5-0.1-1.7-1.3-1.6-1.51.6-0.7-1.8-1.41.6-1.6-1.81.8-1.51.6-1.91.7
Distance traveled after self-admin0.20.20.7-0.8-0.9-0.0-0.80.00.40.0-0.4-0.30.1-0.3-0.60.5-0.20.2-0.50.5
Extensor digitorum longus weight4.317.019.94.3-3.8-4.4-4.0-4.34.5-3.6-4.3-3.64.1-4.2-4.34.2-4.24.2-4.13.8
Bone: elastic displacement0.10.20.6-0.10.70.40.60.2-0.30.40.40.0-0.30.40.3-0.40.4-0.40.4-0.4
Bone: elastic work0.00.00.30.50.40.10.3-0.20.20.3-0.10.00.10.1-0.10.00.00.00.0-0.3
Bone: endosteal estimation0.41.01.71.0-1.3-1.0-1.2-0.81.0-1.0-0.9-0.70.8-1.0-0.91.0-0.91.0-0.91.0
Bone: endosteal perimeter0.91.82.20.7-1.4-1.4-1.5-1.31.3-1.3-1.4-1.01.3-1.4-1.31.4-1.41.4-1.41.5
Epididymis fat weight3.78.726.7-5.23.43.23.03.2-3.22.52.92.4-2.72.62.9-2.62.5-2.32.3-2.0
Delta time in closed arm before/after self-admin0.40.41.6-0.20.50.60.70.2-0.31.30.31.1-0.20.40.3-0.30.5-0.30.3-0.9
Delta time in open arm before/after self-admin2.32.26.31.2-1.7-1.8-1.8-0.91.2-2.5-1.2-1.40.9-1.5-1.11.2-1.61.5-1.21.5
Diff in mean of infusions in LGA sessions0.10.10.40.7-0.1-0.6-0.0-0.30.0-0.4-0.0-0.40.2-0.20.2-0.0-0.30.20.10.2
Delay discount exponential model param0.50.51.8-1.30.50.70.60.7-0.90.40.70.3-0.60.70.8-0.70.9-0.80.6-0.6
Extinction: sum of active levers before priming1.51.52.41.0-1.5-1.0-1.5-1.41.5-0.5-1.4-0.81.4-1.2-1.51.4-1.11.0-1.31.1
Active lever presses in extinction session 60.10.10.6-0.4-0.1-0.6-0.1-0.4-0.0-0.8-0.2-0.60.5-0.30.10.1-0.10.5-0.10.2
Bone: final force0.40.61.10.60.40.50.70.7-0.70.60.80.9-0.80.80.9-0.90.8-0.81.0-1.0
Bone: final moment0.30.51.00.60.40.40.70.6-0.60.50.70.8-0.70.70.8-0.80.7-0.70.9-1.0
Food consumed during 24 hour testing period0.10.10.5-0.0-0.7-0.1-0.5-0.20.30.0-0.40.20.2-0.2-0.40.4-0.20.3-0.30.1
Glucose0.10.10.9-0.9-0.2-0.2-0.2-0.2-0.0-0.4-0.2-0.30.3-0.3-0.10.2-0.20.3-0.30.2
Heart weight3.24.59.5-3.11.72.22.02.4-2.31.82.02.0-2.22.02.1-2.02.0-1.81.8-2.1
Delay discount hyperbolic model param0.30.31.2-1.10.20.40.30.5-0.60.30.50.2-0.40.50.5-0.50.7-0.60.4-0.5
Intermittent access intake day 1-15 change2.72.63.5-1.01.91.61.81.8-1.61.61.61.3-1.81.71.5-1.71.6-1.51.6-1.7
Intermittent access intake escalation3.43.34.8-1.12.21.82.02.0-1.81.81.81.5-2.11.91.7-1.91.8-1.71.8-1.8
Intermittent access intake escalation 23.43.44.1-1.42.01.82.02.0-1.81.71.81.3-2.02.01.8-1.91.9-1.81.8-2.0
Intermitt. access day 1 inactive lever presses0.90.92.00.2-0.7-0.9-1.0-0.80.9-0.9-0.9-0.60.8-1.1-0.91.0-1.31.3-1.11.4
Intermitt. access day 15 inactive lever presses4.24.67.22.0-2.6-2.7-2.1-2.42.0-2.4-2.2-1.92.4-2.2-1.82.0-2.02.4-1.91.4
Intermitt. access escalation Index0.10.10.2-0.2-0.10.30.00.4-0.10.00.2-0.1-0.40.30.1-0.20.4-0.30.2-0.0
Intermittent access day 1 total infusions4.55.28.02.4-2.3-2.5-2.3-2.52.2-2.6-2.2-2.82.4-2.1-2.12.1-2.01.9-2.01.9
Intermittent access day 15 total infusions0.20.31.31.1-0.4-0.6-0.4-0.40.5-0.7-0.4-1.00.3-0.2-0.40.3-0.20.2-0.20.1
Intermittent access terminal intake (last 3 days)0.30.31.41.0-0.5-0.7-0.5-0.50.4-0.8-0.3-1.20.4-0.3-0.30.3-0.30.2-0.20.1
Intermittent access total infusions1.01.13.61.2-0.8-1.2-1.0-1.20.9-1.4-0.9-1.91.1-0.9-0.90.8-0.80.8-0.80.7
Intermittent access day 1 locomotion3.23.35.81.3-1.6-2.0-1.9-1.91.6-2.4-1.6-2.41.8-1.8-1.61.7-1.91.4-1.72.0
Intermittent access day 15 total locomotion0.70.72.30.5-0.5-0.9-0.8-0.80.6-1.4-0.6-1.50.8-0.9-0.60.7-0.90.5-0.71.0
Intermittent access total locomotion0.40.42.00.3-0.1-0.7-0.5-0.60.4-1.2-0.4-1.40.6-0.6-0.40.4-0.70.3-0.50.8
Intermittent access standard deviation0.00.00.2-0.50.40.10.30.1-0.2-0.00.1-0.3-0.10.20.2-0.20.10.20.1-0.3
Left kidney weight0.00.10.5-0.1-0.4-0.4-0.20.3-0.0-0.7-0.1-0.5-0.2-0.20.00.1-0.30.6-0.1-0.2
Right kidney weight0.00.11.0-1.00.20.10.20.3-0.1-0.1-0.1-0.1-0.2-0.10.00.1-0.00.5-0.2-0.3
Cocaine induced anxiety0.40.50.70.6-0.6-0.8-0.7-0.70.7-0.6-0.8-0.40.7-0.7-0.60.7-0.70.8-0.70.5
Post-drug Anxiety0.10.10.30.2-0.10.10.10.5-0.40.00.40.5-0.60.30.5-0.40.3-0.30.5-0.4
Baseline Anxiety0.40.40.7-0.5-0.00.70.40.7-0.70.40.70.5-0.80.70.6-0.70.7-0.80.7-0.7
Tail length0.30.81.50.3-1.2-0.8-1.1-0.80.8-1.0-0.8-0.80.8-0.9-0.90.9-0.90.9-0.90.9
Length with tail0.10.41.0-1.0-0.7-0.2-0.8-0.20.5-0.3-0.7-0.20.4-0.6-0.70.7-0.70.7-0.90.8
Length without tail0.00.10.4-0.6-0.1-0.0-0.2-0.00.30.1-0.40.10.2-0.3-0.30.4-0.30.4-0.50.3
Times rat made contact with spout3.44.07.22.7-2.6-2.1-2.2-2.12.1-1.6-2.1-1.31.9-1.9-2.01.9-1.82.0-1.71.4
Lifetime Intake1.31.54.41.2-1.1-1.4-1.1-1.41.0-1.6-1.1-2.11.4-1.0-1.01.0-0.91.0-0.90.8
Liver weight, left0.40.62.1-1.50.90.80.80.9-0.90.40.80.0-0.80.80.7-0.80.8-0.60.6-0.7
Liver weight, right3.45.612.5-3.52.42.62.52.5-2.42.22.21.7-2.32.32.2-2.22.4-2.02.0-2.3
Locomotor activity0.20.40.70.70.20.50.40.7-0.50.40.70.6-0.80.60.6-0.70.5-0.80.8-0.7
Locomotor testing distance0.10.21.81.3-0.5-0.3-0.50.00.3-0.3-0.10.1-0.2-0.2-0.20.1-0.4-0.00.00.3
Locomotor testing rearing0.60.91.11.1-0.9-1.0-1.0-0.91.0-1.0-0.9-1.10.9-1.0-0.90.9-1.00.8-0.91.0
Locomotion in novel chamber0.40.41.1-1.10.80.50.60.7-0.80.50.70.6-0.60.50.8-0.60.6-0.60.5-0.5
Locomotion in novel chamber post-restriction2.12.53.5-1.91.81.71.61.7-1.61.51.51.2-1.61.61.5-1.51.7-1.41.4-1.7
Fecal boli incidents, locomotor time 10.50.51.80.40.60.70.70.5-0.31.30.31.3-0.60.60.3-0.40.8-0.50.5-1.1
Change in fecal boli incidents, locomotor task0.80.84.9-2.20.81.01.10.8-0.80.70.60.1-0.60.70.5-0.50.8-0.70.4-0.8
Time >=10cm from walls, locomotor time 15.55.68.5-1.42.82.62.62.4-2.02.92.22.1-2.42.52.0-2.22.4-2.42.2-2.7
Bouts of movement, locomotor time 12.42.64.12.0-1.8-1.5-1.7-1.71.8-1.0-1.7-1.31.6-1.5-1.71.6-1.51.6-1.51.4
Total resting periods, locomotor time 11.31.43.71.9-1.3-1.0-1.2-1.31.4-0.5-1.3-0.91.2-1.0-1.31.2-1.01.1-1.01.0
Rest time, locomotor task time 10.10.10.60.30.50.40.30.1-0.10.80.20.5-0.20.40.2-0.30.3-0.30.3-0.3
Distance moved, locomotor task time 10.20.30.5-0.70.30.30.40.6-0.7-0.00.70.1-0.60.40.7-0.60.6-0.60.6-0.2
Vertical activity count, locomotor time 10.40.41.1-1.00.60.60.50.8-0.70.30.70.5-0.80.50.6-0.60.4-0.70.50.0
Time >=10cm from walls, locomotor time 22.42.53.6-1.61.91.51.81.4-1.61.61.61.7-1.41.41.6-1.51.4-1.51.5-1.7
Bouts of movement, locomotor time 20.40.41.7-0.60.31.00.60.6-0.41.30.40.7-0.60.80.2-0.50.7-0.70.4-0.5
Total resting periods, locomotor time 20.10.10.8-0.3-0.20.60.20.2-0.00.90.00.3-0.20.4-0.1-0.10.4-0.30.1-0.2
Rest time, locomotor task time 20.70.91.10.9-1.1-0.9-0.9-1.00.9-0.8-0.9-0.71.1-1.0-0.90.9-0.91.0-0.90.8
Distance moved, locomotor task time 20.10.10.4-0.60.40.10.20.3-0.5-0.20.50.1-0.30.20.6-0.40.3-0.40.4-0.3
Vertical activity count, locomotor time 21.21.32.1-1.31.31.11.01.1-1.30.91.21.5-1.11.01.3-1.10.9-1.01.1-0.7
Light reinforcement 14.98.912.33.1-3.5-3.2-3.3-2.93.0-3.3-2.9-3.12.7-2.9-2.92.8-2.82.7-2.72.7
Light reinforcement 21.41.85.02.2-1.8-1.5-1.6-1.11.3-1.6-1.2-1.50.9-1.1-1.21.1-1.11.0-0.91.2
Bone: marrow area0.61.22.01.1-1.4-1.1-1.3-0.91.1-1.1-1.1-0.80.9-1.1-1.11.1-1.11.2-1.11.1
Bone: maximum diameter0.91.72.31.4-1.4-1.5-1.3-1.31.3-1.3-1.3-0.91.3-1.4-1.21.3-1.31.3-1.21.2
Bone: maximum force0.00.00.20.1-0.2-0.00.1-0.0-0.00.1-0.10.40.00.00.1-0.00.10.10.1-0.3
Bone: maximum moment0.00.00.10.2-0.2-0.10.0-0.10.10.0-0.20.30.1-0.1-0.10.10.00.2-0.1-0.3
Mean time between licks in bursts1.01.44.5-2.11.51.41.31.0-1.21.31.01.0-0.81.01.0-1.01.1-0.90.8-0.9
Mean num. licks in bursts0.10.10.60.8-0.0-0.20.1-0.0-0.2-0.30.30.2-0.10.10.4-0.30.1-0.10.4-0.2
Cd content in liver0.20.20.6-0.40.40.50.40.3-0.20.70.20.8-0.30.30.2-0.20.4-0.40.2-0.4
Co content in liver2.22.55.92.4-1.5-1.4-1.6-1.62.0-0.8-1.8-1.21.4-1.4-2.01.7-1.41.2-1.61.3
Cu content in liver0.30.41.51.0-1.2-0.5-0.8-0.40.7-0.2-0.6-0.10.3-0.4-0.70.6-0.40.3-0.50.2
Fe content in liver0.60.71.3-0.20.40.50.70.9-0.90.40.91.2-1.00.81.0-0.90.9-1.01.0-0.9
K content in liver0.90.91.30.5-0.7-1.0-0.8-1.01.0-0.9-1.0-0.71.0-1.1-0.91.1-1.11.1-1.10.9
Mg content in liver1.71.72.81.4-1.5-1.6-1.4-1.21.2-1.7-1.2-1.11.2-1.4-1.01.2-1.31.2-1.11.3
Mn content in liver1.82.03.00.7-0.7-1.4-1.2-1.71.4-1.1-1.5-0.81.7-1.7-1.31.5-1.71.6-1.61.7
Na content in liver1.31.42.41.0-1.3-1.5-1.3-1.01.1-1.5-1.1-0.91.0-1.3-0.91.1-1.21.2-1.11.2
Rb content in liver0.30.41.61.3-0.5-0.8-0.5-0.50.6-0.8-0.5-0.80.4-0.6-0.50.4-0.60.4-0.40.5
Se content in liver0.70.81.30.1-0.9-1.0-0.8-1.10.8-1.0-0.9-0.81.1-1.0-0.70.9-0.91.0-1.00.8
Sr content in liver0.10.10.5-0.7-0.6-0.1-0.4-0.10.2-0.3-0.3-0.60.2-0.1-0.40.30.00.1-0.30.1
Zn content in liver0.91.01.60.3-1.3-1.0-1.1-1.10.9-1.2-1.0-1.21.1-1.0-0.91.0-0.80.9-1.00.9
Bone: minimum diameter0.30.61.50.6-1.2-0.8-1.0-0.80.8-0.8-0.8-0.30.8-0.8-0.80.8-0.80.7-0.80.7
Time in familiar zone, hab. session 10.00.00.40.1-0.6-0.2-0.3-0.00.0-0.2-0.10.20.0-0.1-0.00.10.10.0-0.0-0.1
Time in novel zone, hab. session 10.70.61.8-1.31.20.90.90.8-0.80.80.80.7-0.70.70.7-0.70.5-0.60.6-0.4
Total zone transitions, hab. session 10.10.20.5-0.00.60.40.60.1-0.30.70.30.7-0.20.40.3-0.30.4-0.30.3-0.5
Total locomotion distance, hab. session 10.00.00.1-0.10.2-0.00.2-0.0-0.10.1-0.10.20.00.00.1-0.00.10.1-0.0-0.2
Locomotion velocity, hab. session 10.30.40.50.4-0.4-0.7-0.4-0.70.6-0.5-0.7-0.60.7-0.6-0.60.6-0.60.7-0.60.4
Time in familiar zone, hab. session 20.20.20.80.9-0.7-0.7-0.5-0.40.2-0.9-0.2-0.40.3-0.4-0.10.2-0.30.2-0.10.3
Time in novel zone, hab. session 20.30.31.4-1.20.80.80.60.5-0.40.90.40.5-0.40.40.3-0.30.4-0.30.2-0.3
Total zone transitions, hab. session 20.10.10.70.90.4-0.10.4-0.30.10.3-0.10.20.20.10.0-0.10.10.10.1-0.3
Total locomotion distance, hab. session 20.50.71.30.7-0.3-1.0-0.4-1.10.9-0.6-1.0-0.81.2-0.8-0.80.9-0.81.1-0.90.5
Locomotion velocity, hab. session 20.60.81.51.0-0.3-1.0-0.5-1.21.0-0.6-1.0-0.91.2-0.9-0.90.9-0.81.1-0.90.5
Novel to familiar place preference ratio1.41.53.2-1.81.51.41.40.9-1.21.61.01.5-0.81.01.1-1.01.1-0.80.9-1.0
Novelty place preference1.91.93.8-1.91.71.61.51.1-1.41.71.21.6-1.01.21.3-1.21.2-1.01.0-1.1
Time in novel zone, NPP test1.92.03.5-1.91.71.71.61.2-1.41.81.31.7-1.11.31.3-1.21.3-1.11.1-1.2
Total zone transitions, NPP test0.81.12.81.7-0.8-1.1-0.9-1.11.3-0.7-1.1-0.81.0-1.0-1.21.1-1.00.9-1.00.9
Total locomotion distance, NPP test1.01.31.81.1-0.9-1.2-1.0-1.31.4-0.7-1.3-0.91.3-1.2-1.31.3-1.11.2-1.21.0
Locomotion velocity, NPP test1.92.73.41.8-1.4-1.8-1.5-1.81.8-1.4-1.8-1.51.8-1.6-1.71.7-1.61.7-1.61.4
Intraocular pressure3.95.46.8-1.71.92.62.22.5-2.22.52.32.1-2.52.62.1-2.32.6-2.62.3-2.4
Delta distance traveled before/after self-admin1.11.21.7-1.20.81.00.81.3-1.30.61.20.9-1.21.11.3-1.21.2-1.11.2-1.0
Delta ambulatory time before/after self-admin0.70.81.2-0.70.80.80.81.1-1.10.21.10.6-1.10.91.1-1.01.0-0.91.0-0.8
Parametrial fat weight1.93.66.0-2.52.32.12.02.2-2.01.62.01.0-2.11.91.8-1.91.7-1.71.7-1.4
Pavlov. Cond. lever latency0.70.94.6-2.11.21.01.00.8-1.00.90.80.8-0.60.70.8-0.70.6-0.50.5-0.5
Pavlov. Cond. magazine entry latency0.60.81.40.7-1.2-0.9-1.1-0.70.9-0.9-0.9-0.90.7-0.8-1.00.9-0.70.7-0.90.8
Pavlov. Cond. change in total contacts0.30.31.40.7-1.2-0.6-0.8-0.40.6-0.6-0.5-0.60.3-0.4-0.60.5-0.30.2-0.40.2
Pavlov. Cond. index score0.60.71.91.4-1.2-0.9-1.0-0.70.9-0.9-0.8-0.90.6-0.7-0.90.7-0.60.6-0.60.5
Pavlov. Cond. latency score0.50.61.71.3-1.1-0.8-0.9-0.70.8-0.8-0.7-0.70.6-0.6-0.80.7-0.50.5-0.60.5
Pavlov. Cond. lever contacts0.70.92.61.6-1.1-1.0-1.0-0.91.0-0.9-0.9-0.90.7-0.8-0.90.8-0.80.7-0.70.7
Pavlov. Cond. magazine entry number0.50.61.6-0.71.30.81.00.6-0.70.80.70.7-0.60.60.8-0.70.5-0.50.6-0.6
Pavlov. Cond. intertrial magazine entries0.60.71.10.70.60.70.80.7-0.70.90.91.0-0.90.90.8-0.90.8-1.01.0-1.0
Pavlov. Cond. lever-magazine prob. diff.1.11.33.01.7-1.5-1.2-1.3-1.01.2-1.1-1.1-1.10.9-1.0-1.21.1-0.90.9-0.90.8
Pavlov. Cond. response bias0.70.82.41.5-1.3-1.0-1.1-0.80.9-1.0-0.8-0.80.7-0.7-0.80.7-0.60.6-0.60.6
Pavlov. Cond. lever latency0.40.51.3-1.10.80.70.80.8-0.90.40.80.6-0.70.60.9-0.70.7-0.60.6-0.6
Pavlov. Cond. magazine entry latency0.20.20.50.20.2-0.4-0.2-0.40.3-0.5-0.3-0.70.4-0.4-0.30.3-0.60.5-0.40.7
Pavlov. Cond. change in total contacts0.10.10.30.40.20.10.0-0.20.40.5-0.3-0.10.2-0.1-0.50.3-0.10.2-0.30.1
Pavlov. Cond. index score0.20.20.30.4-0.2-0.4-0.3-0.50.5-0.3-0.5-0.50.5-0.5-0.50.5-0.50.5-0.50.5
Pavlov. Cond. latency score0.20.20.30.4-0.3-0.4-0.4-0.50.5-0.3-0.5-0.50.5-0.5-0.50.5-0.60.5-0.50.6
Pavlov. Cond. lever contacts0.20.30.60.6-0.5-0.3-0.5-0.50.7-0.1-0.6-0.50.5-0.4-0.80.6-0.50.4-0.60.5
Pavlov. Cond. magazine entry number0.20.30.7-0.1-0.10.40.30.5-0.50.30.50.6-0.60.60.5-0.50.7-0.70.6-0.8
Pavlov. Cond. intertrial magazine entries1.41.84.2-2.00.71.31.01.5-1.61.01.31.5-1.41.31.4-1.31.4-1.31.2-1.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.10.1-0.1-0.0-0.20.20.1-0.2-0.20.2-0.1-0.20.2-0.20.2-0.20.2
Pavlov. Cond. response bias0.50.61.00.9-0.4-0.6-0.7-0.81.0-0.4-0.8-0.90.7-0.7-1.00.8-0.90.8-0.80.9
Time in closed arm before self-admin0.30.31.6-1.30.50.40.40.4-0.6-0.10.5-0.4-0.30.50.5-0.50.5-0.60.4-0.3
Time in closed arm after self-admin0.20.22.1-1.50.20.40.4-0.1-0.30.70.00.00.20.30.1-0.10.5-0.20.0-0.5
Time in open arm before self-admin0.20.21.30.40.70.50.60.3-0.11.10.30.6-0.30.40.1-0.30.5-0.50.3-0.2
Time in open arm after self-admin2.02.24.92.2-1.8-1.7-1.7-1.01.5-1.8-1.3-1.20.9-1.5-1.41.3-1.51.3-1.21.3
Bone: periosteal estimation0.61.21.81.1-1.3-1.2-1.2-1.01.2-1.0-1.1-0.71.0-1.1-1.11.1-1.11.1-1.10.9
Bone: periosteal perimeter0.60.91.30.6-0.9-0.9-0.9-1.01.1-0.7-1.1-0.61.0-1.0-1.11.1-1.01.0-1.10.8
Bone: post-yield work1.41.82.20.8-1.3-1.4-1.3-1.41.4-1.3-1.4-1.11.5-1.5-1.41.4-1.41.5-1.41.4
Progressive ratio test 1 active lever presses0.70.73.1-0.1-0.7-0.9-0.7-0.90.6-1.3-0.7-1.80.9-0.8-0.60.7-0.60.6-0.80.7
Progressive ratio test 1 breakpoint0.70.83.2-0.2-0.7-0.9-0.7-0.90.6-1.3-0.7-1.81.0-0.8-0.60.7-0.70.6-0.80.8
Progressive ratio test 1 inactive lever presses2.02.23.70.7-1.5-1.6-1.4-1.71.4-1.6-1.6-1.91.7-1.5-1.41.5-1.31.7-1.51.1
Progressive ratio test 2 active lever presses0.10.21.40.2-0.4-0.4-0.3-0.30.1-0.8-0.1-1.20.2-0.2-0.10.1-0.1-0.0-0.10.0
Progressive ratio test 2 breakpoint0.10.11.10.2-0.1-0.3-0.0-0.0-0.1-0.70.1-1.0-0.00.00.1-0.10.1-0.10.1-0.2
Progressive ratio test 2 inactive lever presses0.30.41.20.8-0.8-0.8-0.7-0.50.4-1.0-0.4-1.10.4-0.4-0.30.3-0.40.4-0.30.1
Incentive Sensitization - Responses0.20.20.5-0.20.10.30.20.5-0.5-0.20.5-0.5-0.60.50.4-0.50.5-0.70.5-0.5
Incentive Sensitization - Breakpoint0.20.20.4-0.30.10.30.10.5-0.5-0.20.5-0.5-0.60.40.4-0.40.5-0.70.4-0.4
Sum of active levers in priming session hrs 5-61.21.22.41.4-1.6-1.3-1.4-1.21.0-0.7-1.1-0.31.1-1.1-0.91.0-0.91.0-0.91.0
Progressive ratio0.10.11.1-1.00.2-0.2-0.1-0.1-0.3-0.60.1-0.50.2-0.30.20.0-0.20.2-0.10.5
Food seeking constrained by brief footshock0.30.42.31.5-0.7-0.7-0.6-0.60.4-0.7-0.3-0.70.5-0.3-0.20.2-0.40.3-0.10.5
Seeking ratio, punishment vs. effort0.30.41.51.20.20.50.50.4-0.20.90.30.6-0.70.70.2-0.50.6-0.70.7-0.9
Retroperitoneal fat weight3.210.452.2-7.23.33.63.03.4-3.42.82.82.7-2.72.52.8-2.52.6-2.01.9-2.1
Reaction time number correct0.10.10.30.50.30.20.40.2-0.20.20.30.1-0.30.40.3-0.40.3-0.40.5-0.6
Reaction time mean minus median0.10.20.40.40.4-0.00.20.3-0.5-0.30.60.4-0.40.20.7-0.50.1-0.20.50.2
Reaction time mean minus median AUC0.71.01.50.00.80.70.91.0-1.10.61.21.1-1.11.01.2-1.21.0-1.01.2-0.7
Reaction time num false alarms0.20.31.51.2-0.6-0.0-0.4-0.60.90.7-0.70.00.4-0.2-0.90.6-0.20.1-0.5-0.2
Reaction time num false alarms AUC0.50.71.81.4-0.9-0.4-0.7-0.91.20.3-1.0-0.40.8-0.6-1.31.0-0.60.4-0.80.2
Reaction time trials correct on left0.10.10.30.50.30.20.40.2-0.20.20.30.1-0.30.40.3-0.40.3-0.40.5-0.6
Reaction time trials on left0.10.10.30.60.30.20.40.2-0.20.30.30.1-0.30.40.3-0.40.4-0.40.5-0.6
Reaction time mean0.60.81.3-0.20.50.70.70.9-1.10.61.11.0-0.91.01.1-1.11.0-1.01.1-0.9
Reaction time mean AUC0.40.60.9-0.10.30.60.50.7-0.90.40.90.8-0.80.80.9-0.90.9-0.91.0-0.7
Median of all reaction times0.81.01.5-0.30.40.90.81.0-1.10.81.11.2-1.01.11.1-1.11.2-1.11.2-1.2
Reaction time omissions0.30.50.80.40.50.50.60.7-0.60.50.70.9-0.80.60.7-0.70.6-0.90.8-0.7
Reaction time false alarm rate0.71.02.00.9-1.1-0.6-1.0-1.11.3-0.0-1.2-0.51.0-0.9-1.41.2-0.90.8-1.20.6
Reaction time premature initiation rate0.30.51.0-0.3-0.1-0.4-0.5-0.40.7-0.5-0.7-1.00.4-0.7-0.80.8-0.80.8-0.91.0
Reaction time premature initiations0.10.10.4-0.10.2-0.1-0.2-0.10.4-0.1-0.4-0.60.1-0.3-0.50.4-0.40.4-0.40.4
Std. dev. reaction times0.50.71.4-0.20.80.60.80.8-1.10.41.11.0-0.90.81.2-1.10.8-0.81.1-0.5
Reaction time trials completed0.10.10.30.60.30.20.40.2-0.20.30.30.1-0.30.40.3-0.40.4-0.40.5-0.6
Reaction time trials AUC0.10.10.40.60.30.10.40.2-0.20.10.3-0.0-0.30.40.3-0.40.4-0.40.5-0.6
Run reversals in cocaine runway, females0.10.10.2-0.20.1-0.2-0.2-0.40.3-0.2-0.4-0.30.5-0.3-0.30.4-0.30.4-0.40.3
Run reversals in cocaine runway, males0.30.30.60.2-0.3-0.4-0.5-0.50.6-0.4-0.5-0.80.5-0.6-0.70.6-0.40.4-0.60.4
Latency to leave start box in cocaine runway0.40.40.90.9-0.8-0.7-0.9-0.60.6-0.7-0.6-0.30.6-0.7-0.60.6-0.70.6-0.60.4
Latency to leave start box in cocaine runway, F1.21.41.91.3-1.1-1.2-1.4-1.11.2-1.1-1.1-1.01.1-1.2-1.21.2-1.31.0-1.11.1
Latency to leave start box in cocaine runway, M0.10.10.3-0.10.20.30.20.3-0.40.30.40.6-0.30.30.4-0.40.3-0.20.4-0.6
Std. dev. time between licks in bursts0.10.10.3-0.50.40.40.20.2-0.00.50.00.4-0.10.1-0.10.00.1-0.0-0.1-0.0
Total sessions with >9 infusions0.10.10.3-0.30.1-0.10.3-0.4-0.00.1-0.1-0.60.40.00.00.00.3-0.1-0.0-0.4
Short access day 1 total inactive lever presses2.93.25.21.3-2.0-1.9-2.0-1.81.6-2.2-1.7-2.31.8-1.7-1.61.7-1.51.5-1.61.8
Short access day 10 total inactive lever presses0.80.92.20.9-1.1-1.3-0.9-0.90.7-1.0-0.9-0.30.9-1.1-0.60.8-1.11.5-0.80.9
Short access day 1 total infusions0.80.92.20.9-1.0-1.0-0.8-1.30.8-1.0-1.0-1.51.2-0.8-0.80.8-0.50.8-0.70.4
Short access day 10 total infusions1.92.14.01.4-1.7-1.6-1.4-1.91.3-1.6-1.4-2.01.8-1.3-1.31.3-1.11.2-1.21.0
Short access total infusions0.70.82.70.9-0.9-1.1-0.7-1.20.7-1.2-0.8-1.71.2-0.7-0.60.6-0.50.7-0.60.4
Short access day 1 locomotion3.23.55.71.4-1.9-2.1-1.7-2.41.8-1.8-2.0-2.12.4-1.8-1.71.8-1.41.7-1.81.2
Short access day 10 total locomotion0.40.51.20.0-0.2-0.7-0.7-0.50.4-1.0-0.4-0.90.5-0.8-0.40.6-0.90.5-0.61.1
Short access total locomotion0.10.10.8-0.40.1-0.4-0.1-0.3-0.1-0.7-0.0-0.90.3-0.20.10.0-0.20.1-0.10.3
One hour access (0.3 mA shock)0.20.21.61.3-0.4-0.5-0.1-0.30.1-0.5-0.0-0.90.10.10.0-0.10.3-0.40.3-0.6
Compulsive drug intake0.90.91.80.00.10.80.41.2-0.90.81.01.1-1.31.00.9-1.01.0-1.21.1-0.9
One hour access (shock baseline)0.80.93.20.8-0.6-1.1-0.7-1.30.9-1.1-1.0-1.81.3-0.8-0.90.8-0.50.7-0.80.3
Social response proportion0.10.10.3-0.30.5-0.00.1-0.1-0.1-0.30.1-0.30.1-0.20.10.0-0.30.1-0.10.5
Social responses3.34.36.60.2-2.2-2.0-2.1-2.11.9-2.0-2.2-1.42.3-2.3-1.92.2-2.22.6-2.32.0
Social time0.10.10.4-0.30.5-0.10.40.2-0.5-0.40.40.0-0.10.10.6-0.40.10.00.3-0.1
Soleus weight4.412.916.33.8-3.6-3.6-3.7-3.64.0-2.9-3.9-3.23.4-3.5-4.03.8-3.53.4-3.63.3
Bone: stiffness0.00.00.30.0-0.50.0-0.3-0.00.10.1-0.20.30.00.0-0.10.10.10.1-0.1-0.1
Tibialis anterior weight3.110.514.23.8-2.9-3.4-3.1-3.33.5-2.9-3.3-3.03.1-3.3-3.33.2-3.33.3-3.13.0
Time to tail flick, vehicle, before self-admin1.91.93.7-1.91.71.61.71.2-1.31.51.21.0-1.11.41.2-1.21.4-1.11.1-1.6
Time to tail flick, vehicle, after self-admin0.10.10.7-0.80.3-0.00.3-0.3-0.1-0.1-0.1-0.20.4-0.10.10.00.00.5-0.1-0.1
Time to tail flick, test, before self-admin0.40.41.00.6-1.0-0.7-0.5-0.80.6-0.6-0.8-0.70.8-0.4-0.60.6-0.10.7-0.5-0.5
Time to tail flick, test, after self-admin1.41.52.1-0.2-1.1-1.1-1.2-1.31.2-1.3-1.4-1.21.4-1.2-1.31.3-1.01.5-1.40.9
Delta time to tail flick, vehicle, before/after SA0.60.61.01.0-0.6-0.9-0.7-0.90.7-0.9-0.8-0.50.8-0.8-0.60.7-0.90.9-0.70.9
Delta time to tail flick, test, before/after SA1.61.43.00.4-0.9-1.1-1.3-1.01.1-1.3-1.1-1.01.0-1.3-1.21.2-1.51.2-1.31.7
Tibia length0.10.44.7-2.2-0.10.0-0.10.2-0.2-0.6-0.1-0.70.1-0.2-0.00.2-0.00.2-0.40.3
Ambulatory time before self-admin4.54.76.20.4-2.4-2.0-2.3-2.12.2-1.4-2.4-2.12.2-2.2-2.42.4-2.12.2-2.52.3
Ambulatory time after self-admin0.70.81.7-0.6-1.3-0.6-1.2-0.50.8-0.6-1.0-0.80.7-0.9-1.01.0-0.70.9-1.11.1
Bone: tissue strength0.30.20.5-0.30.40.50.50.4-0.40.70.40.6-0.40.50.4-0.50.6-0.40.5-0.7
Total heroin consumption1.11.32.11.4-1.2-1.4-1.3-1.11.0-1.1-0.9-0.81.1-1.2-0.80.9-1.21.1-0.91.3
Bone: trabecular number0.20.45.42.3-0.1-0.60.1-0.10.1-0.30.10.2-0.2-0.00.2-0.2-0.1-0.10.4-0.3
Bone: trabecular spacing0.10.20.8-0.9-0.40.0-0.4-0.40.3-0.0-0.4-0.40.5-0.2-0.50.4-0.20.3-0.50.4
Bone: trabecular thickness0.10.10.70.8-0.3-0.20.00.10.00.0-0.00.3-0.20.10.1-0.10.10.00.2-0.4
Bone: trabecular tissue density0.10.10.30.0-0.3-0.4-0.2-0.40.2-0.4-0.3-0.20.4-0.4-0.20.3-0.30.6-0.30.2
Water consumed over 24 hours1.21.52.41.5-1.5-1.2-1.4-1.11.2-1.1-1.2-0.71.0-1.2-1.21.2-1.21.2-1.11.2
Number of responses in last shaping day0.10.10.8-0.4-0.00.20.4-0.20.10.4-0.3-0.20.30.2-0.20.10.50.2-0.1-0.9