Hub : Genes

Ykt6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Ykt6 0.03 0.02 1.3e-04 0.01 0.03 0.02 0.02 1.3e-02 3.7e-04 1.1e-03 3.8e-03
2 IL mRNA stability Ykt6 0.15 0.11 4.1e-03 0.05 0.08 0.01 0.04 2.9e-02 6.2e-03 1.8e-01 3.8e-02
3 PL mRNA stability Ykt6 0.1 0.07 1.0e-08 0.08 0.08 0.07 0.08 9.5e-09 4.7e-09 1.9e-08 1.1e-08
4 Brain mRNA stability Ykt6 0.05 0.03 6.1e-06 0.05 0.05 0.06 0.05 9.6e-06 1.4e-05 6.8e-06 1.7e-05
5 NAcc mRNA stability Ykt6 0.15 0.11 1.6e-07 0.06 0.06 0.06 0.06 1.1e-07 1.0e-07 5.4e-08 5.7e-08
6 Liver intron excision ratio chr14_80800556_80835512 0.06 0.04 1.6e-05 0.04 0.05 0.04 0.04 1.1e-05 7.4e-06 3.8e-05 2.9e-05
7 OFC gene expression Ykt6 0.25 0.16 2.4e-03 0.26 0.06 0.22 0.24 8.4e-07 1.7e-02 5.9e-06 1.6e-06
8 NAcc isoform ratio XM_039092393.1 0.04 0.03 1.5e-04 0.02 0.03 0.03 0.02 2.6e-03 2.5e-04 1.7e-04 6.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.00.00.20.10.20.1-0.0-0.2-0.0-0.40.1
Area under the delay curve4.44.66.2-2.1-1.7-2.22.1-2.5-2.5-1.9-2.0
BMI with tail0.00.10.2-0.2-0.1-0.30.1-0.3-0.2-0.3-0.5
BMI without tail0.00.00.00.10.10.0-0.1-0.20.00.0-0.1
Body weight1.77.18.9-2.6-2.3-2.82.7-2.7-2.7-2.5-3.0
Weight adjusted by age0.50.51.5-0.7-0.6-0.60.7-0.6-0.7-1.2-0.5
Bone surface0.20.30.6-0.6-0.7-0.40.6-0.3-0.4-0.8-0.0
Bone volume0.20.40.9-0.7-0.7-0.50.6-0.5-0.5-0.9-0.3
Breakpoint value in progressive ratio session1.31.41.8-1.1-1.1-1.21.0-1.3-1.0-1.3-1.3
Number of licking bursts2.73.24.1-1.9-1.9-1.72.0-1.5-1.7-2.0-1.4
Context. condit. distance diff. score3.54.25.32.21.92.3-1.82.12.11.82.3
Locomotion velocity, session 10.30.30.90.20.00.4-0.50.70.60.90.4
Locomotion distance, session 10.20.30.90.51.00.10.0-0.8-0.4-0.5-0.2
Locomotion velocity, session 20.60.71.50.2-0.30.6-0.61.20.91.01.0
Locomotion distance, session 20.50.71.31.01.10.9-1.00.40.60.80.8
Locomotion velocity, session 31.21.42.21.41.51.4-0.71.01.10.71.4
Locomotion distance, session 30.40.51.1-0.7-0.7-0.61.1-0.5-0.6-0.8-0.0
Stereotopy head waving bouts, day 30.30.40.80.80.90.7-0.60.50.50.50.6
Stereotopy head waving duration, day 31.72.02.51.61.61.5-1.51.31.31.41.1
Locomotion velocity, session 70.20.20.4-0.5-0.6-0.40.5-0.1-0.3-0.6-0.1
Locomotion distance, session 70.20.30.60.40.30.5-0.60.50.50.30.8
Stereotopy head waving bouts, day 71.01.22.01.00.81.1-0.51.21.01.41.3
Stereotopy head waving duration, day 70.10.10.20.20.30.20.50.10.00.30.4
Locomotion velocity, session 82.12.55.21.30.91.6-1.11.91.61.62.3
Locomotion distance, session 86.49.410.93.33.13.3-2.92.72.93.03.2
Degree of sensitization distance3.43.45.01.81.61.9-2.21.91.81.91.6
Degree of sensitization stereotypy0.10.10.3-0.0-0.10.00.50.2-0.00.50.3
Conditioned locomotion0.20.31.20.71.10.3-0.1-0.6-0.3-0.3-0.0
Cocaine response after cond. corrected1.21.31.8-1.2-1.2-1.21.3-1.0-1.1-1.2-0.9
Cocaine response after cond. not corrected1.51.72.1-1.3-1.2-1.31.4-1.3-1.3-1.3-1.2
Cocaine response before conditioning0.10.20.50.60.70.4-0.40.00.30.40.1
Saline control response0.60.71.40.70.50.9-0.61.10.90.81.2
Bone: connectivity density0.10.20.30.50.50.5-0.50.30.4-0.00.4
Bone: cortical apparent density0.50.70.9-0.9-0.9-0.90.9-0.6-0.7-0.7-0.9
Bone: cortical area3.04.55.4-2.2-2.0-2.22.3-2.0-2.1-2.1-2.1
Bone: cortical porosity0.10.10.5-0.2-0.1-0.2-0.0-0.4-0.3-0.7-0.4
Bone: cortical porosity0.10.10.30.40.40.3-0.50.10.2-0.10.0
Bone: cortical thickness2.54.16.3-1.9-1.6-2.02.0-2.0-1.9-2.5-2.1
Bone: cortical thickness0.10.20.60.50.80.3-0.2-0.4-0.1-0.3-0.1
Bone: cortical tissue density0.50.61.0-0.9-1.0-0.90.9-0.5-0.7-0.6-0.8
Condit. Reinf. active minus inactive responses0.70.71.8-1.1-1.3-0.91.0-0.4-0.7-0.5-0.4
Condit. Reinf. active-inactive response ratio0.60.61.60.2-0.40.6-0.61.21.00.90.8
Condit. Reinf. active responses0.50.61.2-0.9-1.0-0.81.1-0.5-0.7-0.5-0.2
Condit. Reinf. inactive responses0.91.11.9-0.9-0.6-1.01.4-1.2-1.3-1.2-0.5
Incentive salience index mean1.61.92.9-1.5-1.6-1.41.7-1.2-1.4-1.1-0.9
Condit. Reinf. lever presses1.52.03.2-1.1-0.7-1.41.8-1.7-1.7-1.5-1.0
Condit. Reinf. active minus inactive responses0.30.40.60.60.60.6-0.60.50.50.80.6
Condit. Reinf. active-inactive response ratio0.10.10.1-0.1-0.0-0.30.4-0.3-0.4-0.0-0.1
Condit. Reinf. active responses0.40.60.90.80.90.7-0.80.60.70.90.6
Condit. Reinf. inactive responses1.21.52.01.21.01.2-1.41.21.31.21.0
Condit. Reinf. lever presses0.30.40.50.70.70.7-0.50.50.50.60.7
Condit. Reinf. lever reinforcers received0.30.40.60.70.70.6-0.70.50.60.70.6
Conditioned reinforcement - actives0.10.10.6-0.00.0-0.10.1-0.1-0.10.8-0.0
Conditioned reinforcement - inactives0.00.00.1-0.2-0.1-0.10.1-0.2-0.2-0.0-0.1
Conditioned locomotion0.20.30.8-0.3-0.2-0.50.6-0.4-0.40.9-0.4
Patch foraging indifference point 0 sec0.81.23.9-1.5-2.0-1.01.2-0.2-0.6-0.8-0.4
Patch foraging indifference point AUC0.10.10.2-0.3-0.5-0.10.10.40.10.30.2
Delay disc. indifference point, 0s delay1.01.12.1-0.9-0.8-0.91.0-1.0-1.0-1.5-1.0
Delay disc. indifference point, 16s delay2.32.43.0-1.7-1.6-1.71.5-1.6-1.7-1.0-1.4
Delay disc. indifference point, 2s delay2.83.15.2-1.4-0.9-1.51.6-2.2-2.0-2.3-1.7
Delay disc. indifference point, 24s delay1.61.51.9-1.4-1.2-1.31.1-1.3-1.4-1.0-1.2
Delay disc. indifference point, 4s delay4.85.16.8-2.1-1.6-2.22.3-2.6-2.6-2.3-2.1
Delay disc. indifference point, 8s delay1.71.82.9-1.3-0.9-1.41.4-1.6-1.7-0.9-1.2
Indifference point function ln k0.20.30.8-0.20.1-0.40.3-0.9-0.6-0.6-0.5
Indifference point function log k0.20.30.8-0.20.1-0.40.3-0.9-0.6-0.6-0.5
Patch foraging total patch changes 0 sec0.81.24.3-1.5-2.1-1.01.1-0.1-0.5-0.6-0.3
Patch foraging total patch changes 12 sec0.40.52.2-1.0-1.5-0.70.50.3-0.2-0.1-0.4
Patch foraging total patch changes 18 sec0.70.93.6-1.3-1.9-0.81.10.4-0.30.4-0.2
Patch foraging total patch changes 24 sec2.42.95.31.10.51.6-1.32.31.82.32.0
Patch foraging total patch changes 6 sec0.91.44.4-1.6-2.1-1.21.2-0.3-0.7-0.7-0.6
Patch foraging time to switch 0 sec0.30.41.00.81.00.6-0.60.30.50.50.2
Patch foraging water rate 0 sec1.11.74.1-1.7-2.0-1.41.5-0.6-0.9-0.8-0.8
Patch foraging water rate 12 sec0.10.20.4-0.4-0.5-0.40.7-0.2-0.3-0.5-0.1
Patch foraging water rate 18 sec0.50.72.2-0.10.5-0.60.6-1.5-1.0-0.8-1.0
Patch foraging water rate 24 sec0.10.10.3-0.2-0.2-0.30.4-0.2-0.20.6-0.3
Patch foraging water rate 6 sec0.71.01.5-0.9-0.6-1.01.2-1.2-1.2-0.8-0.9
Seeking ratio, delayed vs. immediate footshock0.30.30.80.40.8-0.10.1-0.9-0.40.7-0.5
Distance traveled before self-admin0.10.10.2-0.2-0.4-0.10.30.30.1-0.30.1
Distance traveled after self-admin0.40.40.7-0.6-0.4-0.60.8-0.8-0.8-0.5-0.5
Extensor digitorum longus weight2.610.413.1-3.6-3.6-3.53.1-2.8-3.0-3.0-3.1
Bone: elastic displacement0.60.71.01.01.00.9-1.00.70.90.30.4
Bone: elastic work0.20.31.0-0.20.0-0.40.2-0.7-0.5-1.0-0.8
Bone: endosteal estimation0.00.10.2-0.3-0.3-0.20.4-0.1-0.30.40.0
Bone: endosteal perimeter0.81.62.5-1.2-0.9-1.31.6-1.5-1.5-0.5-1.3
Epididymis fat weight0.20.51.00.90.90.8-1.00.60.80.10.2
Delta time in closed arm before/after self-admin4.64.48.02.62.82.2-2.21.41.81.71.8
Delta time in open arm before/after self-admin5.45.28.3-2.7-2.9-2.42.4-1.5-1.8-1.9-2.3
Diff in mean of infusions in LGA sessions0.10.10.40.50.60.2-0.2-0.30.00.10.1
Delay discount exponential model param4.04.35.92.01.62.1-2.02.42.41.81.9
Extinction: sum of active levers before priming0.50.50.6-0.7-0.7-0.80.8-0.7-0.60.2-0.7
Active lever presses in extinction session 60.40.41.0-0.2-0.0-0.40.3-0.9-0.5-1.0-0.9
Bone: final force0.20.40.8-0.8-0.9-0.60.6-0.4-0.5-0.4-0.6
Bone: final moment0.40.61.1-0.9-1.0-0.80.8-0.6-0.7-0.6-0.8
Food consumed during 24 hour testing period0.91.13.0-1.4-1.7-1.10.9-0.3-0.7-0.8-0.6
Glucose5.88.728.2-4.2-5.3-3.22.4-0.5-1.6-0.9-1.8
Heart weight0.81.22.30.70.31.0-0.81.51.21.31.3
Delay discount hyperbolic model param4.44.76.42.11.72.2-2.22.52.51.92.0
Intermittent access intake day 1-15 change0.20.20.7-0.4-0.8-0.10.30.40.20.80.2
Intermittent access intake escalation0.20.20.8-0.2-0.60.00.10.50.40.90.2
Intermittent access intake escalation 20.30.30.5-0.1-0.50.3-0.10.70.60.70.6
Intermitt. access day 1 inactive lever presses0.20.20.80.60.90.3-0.3-0.4-0.10.70.1
Intermitt. access day 15 inactive lever presses0.91.01.6-1.2-1.3-1.11.1-0.8-0.8-0.5-1.1
Intermitt. access escalation Index0.10.10.4-0.3-0.60.0-0.00.30.30.10.1
Intermittent access day 1 total infusions0.10.10.40.50.70.3-0.4-0.10.00.20.3
Intermittent access day 15 total infusions0.10.10.1-0.3-0.4-0.10.2-0.1-0.00.4-0.2
Intermittent access terminal intake (last 3 days)0.10.10.2-0.0-0.30.2-0.10.50.40.50.3
Intermittent access total infusions0.00.00.1-0.0-0.10.0-0.0-0.10.00.3-0.0
Intermittent access day 1 locomotion0.60.61.60.91.20.5-0.70.00.21.30.4
Intermittent access day 15 total locomotion0.30.40.7-0.5-0.3-0.70.5-0.7-0.70.4-0.8
Intermittent access total locomotion0.40.40.8-0.5-0.3-0.80.7-0.9-0.90.2-0.6
Intermittent access standard deviation2.62.73.91.41.01.7-1.52.01.91.71.7
Left kidney weight0.10.30.80.10.5-0.20.5-0.9-0.7-0.1-0.6
Right kidney weight0.30.93.21.41.81.0-0.7-0.10.40.50.1
Cocaine induced anxiety2.52.93.8-1.9-2.0-1.81.8-1.4-1.6-1.6-1.5
Post-drug Anxiety0.50.61.2-1.0-1.1-0.80.8-0.6-0.8-0.4-0.4
Baseline Anxiety0.30.30.90.50.60.5-0.50.30.31.00.5
Tail length1.44.25.1-2.0-1.8-2.12.2-2.2-2.2-2.0-1.9
Length with tail2.38.69.7-2.9-2.5-3.03.1-3.1-3.1-2.7-3.1
Length without tail1.33.03.7-1.7-1.5-1.81.8-1.6-1.7-1.5-1.9
Times rat made contact with spout1.82.15.30.5-0.31.1-1.52.31.81.11.6
Lifetime Intake0.00.00.0-0.1-0.1-0.10.0-0.1-0.10.1-0.2
Liver weight, left1.11.84.61.82.11.4-1.70.41.00.70.3
Liver weight, right1.42.48.82.23.01.4-1.4-0.00.70.80.2
Locomotor activity0.10.20.9-0.5-1.0-0.20.20.40.20.60.0
Locomotor testing distance0.20.30.5-0.5-0.4-0.50.7-0.5-0.6-0.6-0.5
Locomotor testing rearing1.01.53.4-1.6-1.8-1.31.5-0.6-0.9-0.8-0.8
Locomotion in novel chamber4.35.26.82.62.62.5-2.42.12.11.42.3
Locomotion in novel chamber post-restriction2.32.84.01.92.01.8-1.71.41.41.61.6
Fecal boli incidents, locomotor time 10.10.10.30.40.50.3-0.4-0.10.3-0.20.2
Change in fecal boli incidents, locomotor task0.50.51.7-0.0-0.40.2-0.21.10.51.30.5
Time >=10cm from walls, locomotor time 10.30.30.50.50.50.5-0.70.50.70.60.2
Bouts of movement, locomotor time 10.20.20.7-0.5-0.9-0.1-0.10.50.20.40.3
Total resting periods, locomotor time 10.20.20.4-0.2-0.50.1-0.30.60.40.60.3
Rest time, locomotor task time 10.10.10.30.0-0.10.2-0.50.40.30.40.4
Distance moved, locomotor task time 10.50.50.8-0.6-0.4-0.80.9-0.9-0.9-0.2-0.9
Vertical activity count, locomotor time 10.10.10.2-0.2-0.2-0.30.4-0.4-0.4-0.1-0.4
Time >=10cm from walls, locomotor time 20.20.31.00.71.00.5-0.5-0.00.20.40.1
Bouts of movement, locomotor time 21.31.43.3-0.8-0.2-1.11.4-1.7-1.8-0.6-0.9
Total resting periods, locomotor time 21.21.22.9-0.8-0.4-1.11.4-1.5-1.7-0.4-0.8
Rest time, locomotor task time 20.20.30.70.3-0.00.4-0.60.80.70.60.4
Distance moved, locomotor task time 20.10.10.20.30.40.3-0.20.00.20.40.3
Vertical activity count, locomotor time 20.20.20.40.50.60.5-0.60.00.4-0.20.3
Light reinforcement 10.20.40.8-0.6-0.4-0.60.9-0.6-0.8-0.3-0.3
Light reinforcement 20.81.12.9-0.40.2-0.81.0-1.7-1.3-1.1-1.1
Bone: marrow area0.00.10.2-0.2-0.2-0.10.3-0.0-0.20.50.1
Bone: maximum diameter3.56.48.9-2.9-3.0-2.72.8-2.0-2.4-2.0-2.1
Bone: maximum force0.30.50.7-0.7-0.7-0.70.8-0.6-0.7-0.5-0.6
Bone: maximum moment0.40.81.0-0.9-0.9-0.91.0-0.8-0.9-0.8-0.8
Mean time between licks in bursts0.10.20.7-0.5-0.8-0.20.60.20.00.20.1
Mean num. licks in bursts4.35.27.01.91.42.1-2.62.62.62.52.2
Cd content in liver0.10.10.30.40.50.3-0.20.10.20.2-0.1
Co content in liver0.00.10.2-0.2-0.4-0.20.30.1-0.10.10.2
Cu content in liver0.20.30.7-0.7-0.8-0.60.3-0.1-0.2-0.4-0.5
Fe content in liver0.40.40.60.50.50.6-0.80.70.60.80.8
K content in liver2.12.03.5-1.0-0.5-1.31.5-1.8-1.5-1.9-1.5
Mg content in liver0.60.61.1-0.7-0.6-0.80.9-0.7-0.7-1.1-0.6
Mn content in liver1.01.12.0-0.6-0.2-0.91.2-1.4-1.2-1.4-0.9
Na content in liver2.72.84.4-2.0-2.1-1.81.7-1.3-1.5-1.4-1.3
Rb content in liver2.63.23.8-1.9-1.8-2.01.7-1.6-1.5-1.9-1.9
Se content in liver2.22.73.8-1.6-1.4-1.71.5-1.6-1.6-1.9-1.6
Sr content in liver1.51.41.7-1.3-1.3-1.31.0-1.1-1.1-1.1-1.1
Zn content in liver1.01.11.7-0.8-0.5-1.11.2-1.3-1.1-1.3-1.0
Bone: minimum diameter0.00.10.1-0.00.2-0.20.4-0.4-0.2-0.3-0.3
Time in familiar zone, hab. session 10.10.10.20.20.20.20.40.10.10.10.5
Time in novel zone, hab. session 10.10.10.4-0.3-0.4-0.2-0.40.10.1-0.6-0.5
Total zone transitions, hab. session 10.00.00.0-0.2-0.1-0.10.1-0.2-0.2-0.10.2
Total locomotion distance, hab. session 10.50.71.2-0.6-0.2-0.71.1-1.1-1.0-0.9-0.4
Locomotion velocity, hab. session 10.10.20.4-0.20.0-0.30.7-0.7-0.6-0.2-0.2
Time in familiar zone, hab. session 21.51.52.21.41.41.3-1.11.01.21.50.9
Time in novel zone, hab. session 21.51.52.9-1.5-1.7-1.30.8-0.7-0.9-1.5-0.9
Total zone transitions, hab. session 21.31.72.4-1.3-1.0-1.41.2-1.5-1.5-1.3-1.1
Total locomotion distance, hab. session 21.52.02.8-1.5-1.2-1.61.5-1.6-1.7-1.1-1.0
Locomotion velocity, hab. session 22.12.94.0-1.7-1.2-1.91.9-2.0-2.0-1.4-1.4
Novel to familiar place preference ratio0.10.10.4-0.5-0.7-0.3-0.10.1-0.00.2-0.0
Novelty place preference0.10.10.4-0.5-0.7-0.2-0.20.20.10.2-0.0
Time in novel zone, NPP test0.10.10.5-0.5-0.7-0.2-0.30.30.20.1-0.0
Total zone transitions, NPP test0.20.20.60.30.7-0.10.1-0.8-0.5-0.5-0.2
Total locomotion distance, NPP test0.50.61.8-0.20.3-0.60.7-1.3-1.0-0.7-0.8
Locomotion velocity, NPP test0.60.92.4-0.40.1-0.80.9-1.6-1.2-0.8-1.0
Intraocular pressure0.30.31.1-0.7-0.8-0.61.0-0.2-0.50.1-0.1
Delta distance traveled before/after self-admin0.10.10.50.20.5-0.0-0.1-0.7-0.40.2-0.1
Delta ambulatory time before/after self-admin0.10.10.50.40.70.2-0.3-0.4-0.20.30.1
Parametrial fat weight1.32.53.5-1.9-1.9-1.81.5-1.5-1.5-0.3-1.8
Pavlov. Cond. lever latency0.10.10.6-0.5-0.7-0.30.10.30.10.2-0.3
Pavlov. Cond. magazine entry latency1.11.42.01.41.41.3-1.01.01.00.51.4
Pavlov. Cond. change in total contacts1.51.62.6-1.4-1.3-1.31.6-1.1-1.3-1.3-0.5
Pavlov. Cond. index score0.70.92.11.31.51.1-0.70.50.70.41.1
Pavlov. Cond. latency score0.60.71.81.11.40.9-0.60.30.50.30.9
Pavlov. Cond. lever contacts0.10.20.60.50.80.3-0.1-0.1-0.0-0.10.5
Pavlov. Cond. magazine entry number1.31.73.2-1.4-1.3-1.50.9-1.2-1.2-0.8-1.8
Pavlov. Cond. intertrial magazine entries1.41.73.7-0.9-0.3-1.21.2-1.9-1.7-1.0-1.3
Pavlov. Cond. lever-magazine prob. diff.0.91.12.51.41.61.2-0.80.60.80.41.2
Pavlov. Cond. response bias0.20.30.80.70.80.6-0.10.20.3-0.20.9
Pavlov. Cond. lever latency4.86.57.3-2.4-2.0-2.72.7-2.7-2.7-2.6-2.7
Pavlov. Cond. magazine entry latency0.00.00.20.10.00.2-0.10.10.1-0.10.4
Pavlov. Cond. change in total contacts0.30.50.60.70.60.7-0.70.60.70.80.7
Pavlov. Cond. index score1.51.92.31.41.21.5-1.51.31.41.31.5
Pavlov. Cond. latency score1.31.62.01.31.21.4-1.41.11.31.11.4
Pavlov. Cond. lever contacts4.25.76.72.21.92.5-2.32.52.42.62.5
Pavlov. Cond. magazine entry number0.40.40.8-0.30.1-0.60.7-0.9-0.8-0.7-0.8
Pavlov. Cond. intertrial magazine entries0.00.10.1-0.2-0.1-0.30.3-0.2-0.3-0.2-0.2
Pavlov. Cond. lever-magazine prob. diff.1.41.82.21.31.21.5-1.51.31.41.21.5
Pavlov. Cond. response bias2.33.24.01.51.11.9-1.71.91.92.02.0
Time in closed arm before self-admin0.30.30.7-0.6-0.7-0.40.3-0.5-0.3-0.8-0.5
Time in closed arm after self-admin1.51.62.21.41.51.3-1.40.81.01.11.2
Time in open arm before self-admin2.12.33.01.61.71.6-1.41.11.11.61.7
Time in open arm after self-admin0.10.10.2-0.3-0.4-0.30.40.0-0.20.2-0.2
Bone: periosteal estimation0.81.62.4-1.4-1.3-1.41.5-1.2-1.3-1.0-1.2
Bone: periosteal perimeter2.13.55.0-1.9-1.5-2.02.2-2.0-2.0-1.3-1.9
Bone: post-yield work0.10.20.4-0.5-0.5-0.50.6-0.4-0.4-0.2-0.2
Progressive ratio test 1 active lever presses0.00.00.10.00.10.0-0.1-0.3-0.20.20.0
Progressive ratio test 1 breakpoint0.10.10.20.40.50.4-0.4-0.00.10.40.4
Progressive ratio test 1 inactive lever presses4.04.46.4-1.9-1.4-2.22.0-2.5-2.3-1.9-2.4
Progressive ratio test 2 active lever presses0.00.00.00.10.00.2-0.1-0.00.10.20.2
Progressive ratio test 2 breakpoint0.00.00.10.0-0.10.2-0.00.00.10.30.2
Progressive ratio test 2 inactive lever presses0.70.81.2-0.9-0.7-1.00.9-1.1-1.00.0-1.0
Incentive Sensitization - Responses0.10.10.20.1-0.10.2-0.10.30.30.50.1
Incentive Sensitization - Breakpoint0.10.10.30.1-0.10.3-0.20.40.50.50.2
Sum of active levers in priming session hrs 5-61.71.62.2-1.2-1.0-1.31.2-1.3-1.2-1.5-1.5
Progressive ratio0.10.10.40.50.60.3-0.3-0.30.20.30.0
Food seeking constrained by brief footshock3.74.66.7-1.8-1.2-2.12.2-2.6-2.4-2.4-2.1
Seeking ratio, punishment vs. effort1.92.43.2-1.5-1.3-1.61.7-1.4-1.7-1.8-1.3
Retroperitoneal fat weight0.10.30.6-0.20.0-0.50.3-0.8-0.60.1-0.8
Reaction time number correct0.10.20.7-0.1-0.40.00.00.50.30.80.5
Reaction time mean minus median2.93.95.21.81.32.0-2.02.32.22.02.0
Reaction time mean minus median AUC2.33.04.21.61.21.8-1.82.11.91.61.8
Reaction time num false alarms1.01.32.4-1.0-0.8-1.11.2-1.3-1.2-1.5-0.8
Reaction time num false alarms AUC1.11.63.1-0.9-0.6-1.11.3-1.5-1.4-1.8-1.0
Reaction time trials correct on left0.10.20.7-0.1-0.40.00.00.50.30.80.5
Reaction time trials on left0.10.20.8-0.1-0.40.0-0.00.50.30.90.6
Reaction time mean0.71.01.31.11.11.1-1.10.81.01.00.7
Reaction time mean AUC1.11.42.01.41.41.3-1.30.91.21.20.8
Median of all reaction times0.20.30.80.70.90.5-0.70.20.40.60.1
Reaction time omissions0.91.31.81.21.21.2-1.30.91.11.20.9
Reaction time false alarm rate1.31.84.3-0.8-0.4-1.11.2-1.7-1.5-2.1-1.2
Reaction time premature initiation rate1.52.04.01.82.01.6-1.60.71.20.61.2
Reaction time premature initiations1.01.31.81.31.31.3-1.30.81.10.81.2
Std. dev. reaction times1.82.63.11.61.31.7-1.71.71.81.61.5
Reaction time trials completed0.10.20.8-0.1-0.40.0-0.00.50.30.90.6
Reaction time trials AUC0.10.10.5-0.2-0.5-0.10.10.30.20.70.4
Run reversals in cocaine runway, females0.20.20.50.50.70.5-0.20.2-0.00.60.6
Run reversals in cocaine runway, males0.10.10.3-0.5-0.6-0.40.30.0-0.2-0.2-0.3
Latency to leave start box in cocaine runway0.40.40.9-0.4-0.3-0.60.7-0.6-0.7-0.7-1.0
Latency to leave start box in cocaine runway, F1.01.11.7-0.9-0.7-1.01.0-0.9-1.1-1.3-1.3
Latency to leave start box in cocaine runway, M0.40.40.70.70.70.6-0.50.70.60.80.4
Std. dev. time between licks in bursts0.10.10.2-0.1-0.20.10.40.20.00.30.4
Total sessions with >9 infusions0.00.00.10.20.10.2-0.20.20.20.00.2
Short access day 1 total inactive lever presses3.74.14.8-2.0-1.8-2.22.2-2.0-2.2-2.1-1.9
Short access day 10 total inactive lever presses0.00.00.20.20.40.1-0.1-0.3-0.10.10.1
Short access day 1 total infusions0.10.20.50.50.70.3-0.40.20.20.30.2
Short access day 10 total infusions0.20.20.50.60.70.5-0.50.20.30.10.2
Short access total infusions0.30.30.60.70.80.6-0.60.50.50.20.5
Short access day 1 locomotion0.80.82.11.21.40.8-0.80.40.50.61.0
Short access day 10 total locomotion0.40.51.40.71.20.3-0.5-0.5-0.21.20.3
Short access total locomotion2.62.74.51.92.11.6-1.71.01.21.81.5
One hour access (0.3 mA shock)0.00.00.20.20.20.2-0.1-0.2-0.00.40.2
Compulsive drug intake1.91.92.41.51.51.5-1.31.31.21.21.5
One hour access (shock baseline)0.40.40.9-0.7-0.6-0.70.6-0.9-0.7-0.1-0.7
Social response proportion1.82.02.6-1.5-1.3-1.61.0-1.4-1.3-1.4-1.6
Social responses1.72.23.8-1.8-1.9-1.81.4-1.1-1.3-0.7-1.4
Social time0.20.30.6-0.7-0.7-0.80.4-0.3-0.4-0.2-0.7
Soleus weight1.23.65.2-1.5-1.1-1.92.0-2.2-2.0-1.9-2.3
Bone: stiffness0.10.10.50.10.10.20.10.30.10.70.2
Tibialis anterior weight0.82.64.3-1.9-2.1-1.71.6-1.2-1.4-1.2-1.6
Time to tail flick, vehicle, before self-admin0.30.31.0-0.10.3-0.40.3-1.0-0.8-0.4-0.4
Time to tail flick, vehicle, after self-admin0.40.41.2-0.3-0.1-0.50.4-1.1-0.8-0.9-0.4
Time to tail flick, test, before self-admin1.71.62.61.10.71.4-1.31.61.60.81.2
Time to tail flick, test, after self-admin4.74.96.7-2.1-1.7-2.22.2-2.6-2.4-2.5-1.9
Delta time to tail flick, vehicle, before/after SA0.00.00.20.00.10.0-0.1-0.2-0.1-0.5-0.1
Delta time to tail flick, test, before/after SA3.83.44.7-1.8-1.5-2.02.0-2.0-2.2-1.4-1.7
Tibia length0.10.41.00.20.6-0.10.6-1.0-0.6-0.4-1.0
Ambulatory time before self-admin0.40.40.8-0.6-0.7-0.50.8-0.3-0.5-0.9-0.4
Ambulatory time after self-admin0.50.61.2-0.6-0.4-0.70.8-1.1-0.9-0.8-0.7
Bone: tissue strength0.70.71.70.3-0.20.6-0.61.31.01.10.7
Total heroin consumption0.00.00.2-0.1-0.2-0.1-0.2-0.30.0-0.1-0.4
Bone: trabecular number0.00.00.10.20.20.2-0.1-0.00.1-0.30.1
Bone: trabecular spacing0.70.91.2-1.1-1.0-1.01.0-0.7-0.9-0.8-0.9
Bone: trabecular thickness0.30.31.20.81.10.6-0.5-0.20.10.40.2
Bone: trabecular tissue density0.81.22.90.70.50.9-1.21.21.01.71.0
Water consumed over 24 hours0.40.52.1-1.1-1.4-0.70.40.1-0.2-0.4-0.2
Number of responses in last shaping day0.10.10.2-0.10.1-0.30.4-0.3-0.4-0.1-0.1