Hub : Genes

Wdr45b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio NM_001039587.1 0.12 0.06 3.4e-09 0.07 0.06 0.07 0.07 2.2e-08 3.2e-07 6.0e-08 5.6e-08
2 Adipose isoform ratio XM_039086445.1 0.04 0.02 8.0e-04 0.01 0.01 0 0.01 2.4e-02 6.9e-02 8.5e-02 6.1e-02
3 NAcc gene expression Wdr45b 0.06 0.03 1.6e-05 0.04 0.02 0.02 0.03 6.0e-06 8.2e-04 7.0e-04 2.7e-04
4 Brain alternative polyA XM_039086444.1 0.02 0.02 8.2e-03 0.03 0.02 0.02 0.01 1.6e-03 8.7e-03 1.1e-02 1.3e-02
5 Liver alternative polyA NM_001039587.1 0.2 0.09 6.5e-10 0.07 0.07 0.07 0.07 2.7e-08 3.3e-08 7.7e-08 5.6e-08
6 Liver alternative polyA XM_039086444.1 0.19 0.09 4.2e-08 0.09 0.06 0.08 0.08 2.7e-10 8.3e-07 7.5e-09 1.6e-09
7 Adipose isoform ratio XM_039086444.1 0.08 0.04 3.6e-06 0.04 0.05 0.03 0.03 2.0e-05 6.4e-06 2.1e-04 9.6e-05
8 Adipose gene expression Wdr45b 0.06 0.04 9.7e-04 0.02 0.03 0.02 0.02 5.9e-03 8.2e-04 5.1e-03 2.9e-03
9 PL alternative polyA XM_039086444.1 0.02 0.01 8.1e-03 0 0.02 0 0 1.7e-01 5.8e-03 7.8e-02 1.0e-01
10 Liver isoform ratio XM_039086444.1 0.18 0.08 2.9e-07 0.06 0.06 0.08 0.07 3.1e-07 1.8e-07 1.4e-09 5.3e-08
11 Liver mRNA stability Wdr45b 0.06 0.05 9.6e-03 0.02 0.01 0.01 0.01 2.3e-03 9.5e-03 4.5e-02 7.4e-03
12 Adipose alternative polyA NM_001039587.1 0.17 0.07 4.3e-10 0.09 0.06 0.07 0.07 5.0e-10 5.2e-07 4.0e-08 3.6e-08
13 Adipose alternative polyA XM_039086445.1 0.1 0.05 1.3e-04 0.05 0.02 0.03 0.03 5.8e-06 5.2e-03 5.5e-04 2.0e-04
14 RMTg alternative polyA NM_001039587.1 0.23 0.12 1.7e-03 0.02 0.1 0.07 0.05 9.7e-02 1.5e-03 4.7e-03 2.0e-02
15 NAcc alternative polyA NM_001039587.1 0.03 0.02 4.5e-03 0.02 0.01 0.01 0.01 5.1e-03 2.5e-02 1.8e-02 4.6e-02
16 Liver isoform ratio NM_001039587.1 0.15 0.06 1.6e-08 0.07 0.06 0.06 0.07 2.0e-08 2.3e-07 1.6e-07 4.8e-08
17 PL gene expression Wdr45b 0.03 0.02 9.4e-03 0.02 0.02 0.01 0.01 1.7e-03 4.4e-03 1.2e-02 1.6e-02
18 Liver gene expression Wdr45b 0.1 0.06 5.5e-04 0.02 0.03 0.02 0.02 2.2e-03 7.3e-04 1.1e-03 1.4e-03
19 OFC gene expression Wdr45b 0.24 0.12 2.5e-03 -0.01 0.07 0.03 0.01 5.8e-01 8.8e-03 7.5e-02 2.2e-01
20 Adipose alternative polyA XM_039086444.1 0.04 0.02 4.7e-04 0.01 0.03 0.03 0.02 7.5e-03 2.2e-04 8.4e-04 2.2e-03
21 Brain mRNA stability Wdr45b 0.04 0.03 1.4e-04 0.03 0.04 0.04 0.03 8.6e-04 5.7e-05 3.3e-04 4.1e-04
22 Adipose alternative polyA NM_001039587.1 0.1 0.07 6.5e-05 0.02 0.04 0.02 0.03 6.0e-03 2.1e-05 1.3e-03 5.1e-04
23 Adipose alternative polyA XM_039086444.1 0.11 0.07 2.1e-05 0.02 0.04 0.03 0.03 4.2e-03 8.3e-06 2.8e-04 1.9e-04
24 PL mRNA stability Wdr45b 0.1 0.06 1.1e-04 0.01 0.03 0.02 0.03 8.5e-03 4.1e-04 1.8e-03 7.9e-04
25 Liver intron excision ratio chr10_106599555_106600512 0.1 0.07 4.4e-03 0 0.03 0.01 0 1.4e-01 4.0e-04 7.2e-03 8.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.20.31.7-0.00.0-1.2-0.4-0.50.5-0.40.40.20.9-0.2-0.30.30.3-0.8-0.6-0.80.90.2-0.30.10.3-0.30.21.3
Area under the delay curve0.50.62.80.3-0.30.81.10.5-0.50.0-0.3-1.5-0.51.30.4-0.4-0.70.40.50.4-0.60.5-0.2-1.3-0.00.0-1.7-0.7
BMI with tail0.31.15.02.2-2.2-1.3-0.81.1-1.11.0-0.60.9-0.92.00.8-0.80.0-0.00.80.1-0.6-0.1-0.00.00.1-0.0-1.4-1.1
BMI without tail3.77.618.7-1.91.9-4.3-3.6-3.03.0-2.23.02.02.5-2.7-2.92.93.3-3.7-3.0-3.73.11.6-2.41.42.2-2.21.32.0
Body weight0.52.112.32.2-2.2-2.7-3.50.7-0.71.4-0.93.0-0.80.61.0-1.00.1-0.90.7-0.8-0.3-0.90.21.90.1-0.1-0.40.3
Weight adjusted by age0.70.83.20.9-0.9-0.6-1.50.7-0.71.0-0.81.8-0.6-0.80.8-0.8-0.30.40.90.4-0.2-1.20.81.5-0.40.41.20.7
Bone surface0.40.61.8-0.90.9-0.6-1.4-0.80.8-0.50.40.60.8-1.1-0.70.70.6-0.7-0.8-0.80.8-0.0-0.30.60.7-0.71.11.3
Bone volume0.30.51.3-0.60.6-0.9-0.9-0.80.7-0.50.60.50.9-1.0-0.70.70.6-0.9-0.8-0.90.90.1-0.30.50.5-0.50.91.2
Breakpoint value in progressive ratio session1.01.12.91.0-1.00.80.11.1-1.21.2-1.00.1-1.60.51.0-1.0-1.61.21.01.1-1.7-0.80.80.1-0.70.6-1.2-1.7
Number of licking bursts0.50.51.0-0.90.9-0.9-0.4-0.70.7-0.80.90.00.9-0.5-0.60.61.0-0.9-0.9-0.91.00.6-0.7-0.00.6-0.60.40.7
Context. condit. distance diff. score2.02.54.0-1.31.3-1.9-1.7-1.81.8-1.71.9-0.01.8-0.9-1.71.71.8-2.0-1.7-2.01.91.4-1.7-0.31.5-1.50.21.1
Locomotion velocity, session 12.22.34.11.3-1.32.01.01.9-1.81.4-1.5-0.4-1.51.01.8-1.8-1.62.01.82.0-1.7-1.21.6-0.2-1.61.6-0.2-1.7
Locomotion distance, session 10.81.14.60.4-0.4-0.11.30.2-0.3-0.80.4-1.9-0.12.10.3-0.30.5-0.10.3-0.10.01.4-1.2-2.11.3-1.2-1.8-0.6
Locomotion velocity, session 21.41.75.10.8-0.81.82.31.1-1.00.2-0.7-2.1-1.42.10.7-0.7-0.91.30.91.3-1.40.50.0-2.0-0.00.0-2.0-1.6
Locomotion distance, session 20.50.72.80.4-0.4-0.90.3-0.30.3-0.70.5-1.00.21.7-0.20.20.7-0.7-0.2-0.60.41.3-1.2-1.31.1-1.1-1.40.1
Locomotion velocity, session 31.82.13.81.5-1.51.71.31.5-1.51.0-1.4-1.4-1.51.91.9-1.9-1.81.61.71.6-1.5-0.40.8-1.2-0.90.9-1.7-0.9
Locomotion distance, session 31.71.97.71.1-1.11.51.91.2-1.10.4-0.8-2.2-1.12.81.1-1.1-1.41.21.21.2-1.20.50.0-2.0-0.30.3-2.5-1.1
Stereotopy head waving bouts, day 30.91.02.51.5-1.51.00.81.2-1.20.8-1.0-0.2-1.11.01.6-1.6-0.71.11.31.1-1.1-0.50.7-0.2-0.40.4-0.3-0.8
Stereotopy head waving duration, day 30.50.61.91.1-1.10.50.60.9-0.90.4-0.6-0.2-1.00.81.4-1.4-0.10.61.00.7-0.8-0.10.2-0.30.2-0.2-0.2-0.6
Locomotion velocity, session 70.30.31.4-0.00.00.50.8-0.10.1-0.50.2-1.20.10.8-0.60.6-0.10.0-0.4-0.0-0.00.6-0.5-1.10.5-0.5-0.9-0.2
Locomotion distance, session 71.31.66.1-0.60.60.11.2-0.80.8-1.41.2-2.50.71.5-1.41.40.5-0.6-1.0-0.60.61.9-1.5-2.31.1-1.0-2.0-0.3
Stereotopy head waving bouts, day 70.20.20.50.5-0.5-0.4-0.20.6-0.50.2-0.20.5-0.70.40.6-0.60.5-0.00.40.0-0.30.0-0.20.20.7-0.70.0-0.4
Stereotopy head waving duration, day 70.10.20.50.5-0.5-0.4-0.30.4-0.40.3-0.40.7-0.30.40.7-0.70.20.00.50.0-0.2-0.30.10.50.3-0.30.30.1
Locomotion velocity, session 80.60.72.80.3-0.3-0.90.3-0.20.1-0.60.4-1.10.51.70.2-0.20.1-0.70.1-0.70.81.1-1.0-1.30.8-0.8-1.61.0
Locomotion distance, session 82.53.77.5-0.90.9-2.7-1.3-1.91.9-2.32.2-0.91.70.5-1.51.52.4-2.5-1.6-2.42.02.6-2.7-1.42.7-2.6-1.11.2
Degree of sensitization distance2.12.24.9-1.61.6-1.4-1.2-1.81.8-1.31.50.51.7-1.7-2.22.21.4-1.6-2.0-1.61.70.7-0.90.50.7-0.71.21.2
Degree of sensitization stereotypy0.10.10.60.3-0.3-0.8-0.50.2-0.20.1-0.10.6-0.30.30.4-0.40.4-0.20.3-0.2-0.10.0-0.20.30.5-0.5-0.0-0.2
Conditioned locomotion2.12.57.4-1.31.3-2.7-2.3-1.71.7-0.91.21.71.9-1.6-1.01.01.6-2.0-1.4-2.01.90.3-0.91.40.9-0.91.42.1
Cocaine response after cond. corrected0.40.41.30.3-0.30.70.30.9-0.80.7-0.7-0.1-0.60.40.6-0.6-1.20.60.60.6-0.6-0.70.80.0-1.01.0-0.5-0.3
Cocaine response after cond. not corrected0.40.41.00.4-0.40.80.90.8-0.80.4-0.5-0.7-0.70.50.7-0.7-1.00.60.60.6-0.6-0.20.4-0.5-0.60.6-1.0-0.6
Cocaine response before conditioning0.50.62.0-0.10.1-0.01.4-0.40.3-0.90.6-1.3-0.10.70.0-0.00.7-0.2-0.0-0.20.01.3-1.1-1.41.2-1.2-1.1-0.5
Saline control response1.01.36.0-1.11.1-1.5-1.6-1.01.0-0.10.31.51.3-1.3-0.50.50.1-1.2-0.6-1.21.4-0.50.11.6-0.50.51.32.4
Bone: connectivity density0.61.03.0-1.11.1-1.0-0.5-1.01.0-1.11.0-0.41.4-0.5-0.80.80.8-1.3-1.0-1.31.50.9-1.0-0.40.9-0.90.21.7
Bone: cortical apparent density0.81.02.70.6-0.61.61.61.1-1.00.4-0.7-1.6-0.81.10.8-0.8-1.21.31.11.3-0.9-0.00.5-1.2-0.90.9-1.1-1.0
Bone: cortical area3.34.917.44.2-4.2-1.9-2.12.3-2.32.8-2.62.7-2.02.12.9-2.9-1.40.52.40.7-1.5-1.81.41.6-0.80.9-0.90.2
Bone: cortical porosity2.73.06.11.7-1.71.60.01.9-1.92.2-2.01.5-2.5-0.21.3-1.3-1.52.11.52.1-2.3-2.12.11.5-1.61.50.7-1.9
Bone: cortical porosity1.82.04.01.4-1.41.1-0.31.5-1.51.8-1.61.6-2.0-0.41.0-1.0-1.11.61.21.6-1.8-1.81.71.5-1.31.20.9-1.4
Bone: cortical thickness6.811.135.05.9-5.9-1.1-1.83.9-3.84.3-4.03.0-3.13.24.4-4.4-2.71.73.91.9-2.6-2.92.71.9-2.62.7-1.3-0.5
Bone: cortical thickness3.84.413.53.7-3.7-0.7-0.52.8-2.72.6-2.31.6-2.12.42.6-2.6-1.41.12.61.2-1.7-1.61.60.9-1.71.8-0.9-1.1
Bone: cortical tissue density0.81.03.00.4-0.41.71.71.0-0.90.3-0.6-1.7-0.70.90.6-0.6-1.11.31.01.3-0.9-0.00.5-1.3-0.90.9-0.9-1.1
Condit. Reinf. active minus inactive responses0.70.84.7-0.40.4-1.3-2.2-0.50.5-0.00.31.40.7-1.0-0.50.50.4-1.0-0.3-1.00.9-0.40.01.3-0.00.01.01.4
Condit. Reinf. active-inactive response ratio0.30.32.30.4-0.4-0.8-1.30.1-0.10.3-0.40.70.3-0.1-0.30.3-0.4-0.50.0-0.50.4-0.40.20.6-0.10.10.21.5
Condit. Reinf. active responses1.61.99.0-1.11.1-2.1-3.0-1.11.1-0.40.92.01.2-1.8-1.01.01.1-1.7-0.8-1.61.4-0.2-0.31.80.1-0.21.71.5
Condit. Reinf. inactive responses0.91.12.6-1.51.5-1.1-1.6-1.11.1-0.61.11.11.0-1.5-0.70.71.2-1.1-0.8-1.01.00.1-0.31.10.1-0.11.40.3
Incentive salience index mean0.81.04.5-0.80.8-1.4-2.1-0.90.9-0.50.71.11.0-1.2-0.80.80.8-1.3-0.6-1.31.10.0-0.41.00.4-0.41.01.2
Condit. Reinf. lever presses0.71.01.9-1.41.4-0.8-0.5-1.11.1-1.21.3-0.40.9-0.7-1.11.11.2-1.0-1.0-1.10.91.1-1.1-0.51.0-1.00.00.0
Condit. Reinf. active minus inactive responses0.30.31.70.7-0.7-1.0-1.10.3-0.30.5-0.41.10.0-0.00.4-0.4-0.2-0.30.3-0.30.3-0.40.10.70.3-0.20.01.3
Condit. Reinf. active-inactive response ratio0.80.94.00.8-0.8-0.9-1.80.8-0.81.0-0.82.0-0.3-0.90.7-0.7-0.3-0.00.60.0-0.0-1.20.81.7-0.40.51.00.9
Condit. Reinf. active responses0.10.21.20.3-0.3-0.9-0.7-0.10.10.1-0.10.40.30.30.1-0.1-0.1-0.4-0.0-0.40.40.0-0.30.20.5-0.5-0.41.1
Condit. Reinf. inactive responses0.20.31.80.0-0.00.10.5-0.20.1-0.2-0.0-1.10.11.30.2-0.2-0.5-0.00.1-0.0-0.00.6-0.5-1.10.4-0.4-1.40.3
Condit. Reinf. lever presses0.30.41.3-0.20.2-1.1-0.5-0.70.7-0.60.70.10.6-0.2-0.70.70.7-0.9-0.7-0.90.80.6-0.7-0.00.6-0.6-0.10.8
Condit. Reinf. lever reinforcers received0.20.31.10.0-0.0-1.1-0.8-0.30.3-0.30.20.30.30.2-0.20.20.3-0.6-0.3-0.60.50.3-0.60.00.9-0.8-0.41.0
Conditioned reinforcement - actives0.40.41.0-0.80.8-0.8-0.0-0.60.5-0.80.9-0.30.6-0.2-0.70.71.0-0.9-0.7-0.80.80.8-0.8-0.30.5-0.50.10.3
Conditioned reinforcement - inactives0.20.21.2-0.10.1-0.5-1.10.1-0.10.4-0.00.7-0.4-0.6-0.10.1-0.5-0.4-0.1-0.3-0.0-0.40.30.8-0.90.8-0.00.0
Conditioned locomotion0.20.20.4-0.60.6-0.3-0.0-0.40.4-0.60.5-0.2-0.4-0.5-0.40.40.6-0.4-0.5-0.30.20.6-0.6-0.20.5-0.60.10.1
Patch foraging indifference point 0 sec0.10.10.7-0.30.3-0.2-0.3-0.40.4-0.10.1-0.00.5-0.5-0.20.2-0.4-0.3-0.2-0.30.4-0.10.10.2-0.30.30.10.8
Patch foraging indifference point AUC0.20.21.0-0.30.3-0.5-0.4-0.50.4-0.40.60.30.4-1.0-0.40.40.7-0.6-0.2-0.60.50.1-0.20.3-0.00.00.8-0.2
Delay disc. indifference point, 0s delay0.40.51.40.8-0.80.00.21.1-1.10.6-0.7-0.2-0.91.21.0-1.0-0.60.40.80.5-0.4-0.20.3-0.3-0.30.3-0.80.1
Delay disc. indifference point, 16s delay1.21.24.0-0.60.6-0.21.0-0.50.5-1.31.0-2.00.41.1-0.70.70.6-0.7-0.7-0.70.41.8-1.5-2.01.3-1.3-1.8-0.3
Delay disc. indifference point, 2s delay0.30.30.80.5-0.50.70.60.6-0.60.3-0.5-0.5-0.80.80.7-0.7-0.50.60.70.6-0.8-0.00.1-0.6-0.10.1-0.8-0.9
Delay disc. indifference point, 24s delay1.91.85.61.0-1.02.22.41.0-1.20.5-1.0-2.0-1.41.70.9-0.9-1.41.50.81.4-1.70.10.4-1.7-0.20.2-1.8-1.6
Delay disc. indifference point, 4s delay0.40.51.50.4-0.40.30.70.9-0.80.5-0.7-0.7-0.31.20.4-0.4-1.20.50.60.5-0.1-0.20.4-0.6-0.80.9-1.00.7
Delay disc. indifference point, 8s delay0.90.92.30.8-0.81.20.71.0-1.00.9-1.0-0.8-0.61.30.9-0.9-1.50.91.10.9-1.0-0.50.7-0.6-0.90.9-1.4-0.7
Indifference point function ln k0.70.96.20.9-0.90.61.50.7-0.70.3-0.7-1.3-0.52.50.7-0.7-0.70.70.60.7-0.60.4-0.2-1.40.3-0.2-2.0-0.1
Indifference point function log k0.70.96.20.9-0.90.61.50.7-0.70.3-0.7-1.3-0.52.50.7-0.7-0.70.70.60.7-0.60.4-0.2-1.40.3-0.2-2.0-0.1
Patch foraging total patch changes 0 sec0.10.10.9-0.30.3-0.3-0.3-0.40.4-0.10.1-0.10.5-0.4-0.10.1-0.4-0.5-0.1-0.40.5-0.0-0.00.1-0.20.3-0.10.9
Patch foraging total patch changes 12 sec0.10.21.0-0.20.20.0-0.4-0.30.30.00.20.30.2-1.0-0.10.1-0.0-0.2-0.2-0.10.1-0.40.40.5-0.70.70.8-0.4
Patch foraging total patch changes 18 sec0.40.50.9-0.40.4-1.0-0.0-0.90.9-0.80.8-0.60.9-0.9-0.40.40.3-0.9-0.3-0.90.90.7-0.7-0.40.4-0.4-0.10.9
Patch foraging total patch changes 24 sec0.20.21.1-0.10.1-0.7-0.5-0.50.4-0.10.20.40.6-1.00.3-0.3-0.2-0.60.1-0.60.7-0.20.10.5-0.40.40.51.0
Patch foraging total patch changes 6 sec0.20.31.9-0.00.0-0.2-0.7-0.20.10.10.10.80.2-1.4-0.20.20.1-0.3-0.0-0.20.3-0.50.40.9-0.60.61.10.3
Patch foraging time to switch 0 sec0.10.20.5-0.50.50.70.50.00.0-0.40.3-0.6-0.2-0.1-0.20.20.30.3-0.20.3-0.20.4-0.3-0.60.6-0.6-0.1-0.6
Patch foraging water rate 0 sec0.40.73.20.1-0.1-1.8-1.6-0.80.8-0.00.40.81.0-0.6-0.20.2-0.3-1.3-0.4-1.31.1-0.1-0.10.8-0.70.7-0.11.5
Patch foraging water rate 12 sec0.30.51.81.4-1.4-1.2-0.60.5-0.50.3-0.1-0.1-0.11.21.0-1.0-0.3-0.50.9-0.40.20.2-0.2-0.4-0.30.4-1.30.1
Patch foraging water rate 18 sec0.40.52.60.5-0.5-1.6-0.6-0.50.4-0.50.5-0.10.60.50.1-0.10.5-1.1-0.1-1.00.90.8-1.0-0.40.9-0.8-0.91.2
Patch foraging water rate 24 sec0.70.95.30.5-0.5-2.3-1.7-0.60.6-0.50.60.30.80.10.5-0.50.2-1.5-0.0-1.41.20.7-1.0-0.10.7-0.7-0.91.7
Patch foraging water rate 6 sec0.81.25.01.9-1.9-0.6-0.21.0-1.00.7-0.6-0.5-0.72.21.6-1.6-1.0-0.11.40.1-0.50.2-0.1-0.9-0.50.6-2.2-0.4
Seeking ratio, delayed vs. immediate footshock0.50.62.2-0.40.4-1.4-1.3-0.20.3-0.00.21.10.8-0.8-0.50.50.2-0.8-0.7-0.81.0-0.40.11.0-0.40.40.81.5
Distance traveled before self-admin1.01.02.50.7-0.70.6-0.60.5-0.91.3-1.41.1-1.0-0.90.5-0.5-1.60.90.60.9-0.8-1.51.41.3-1.41.40.80.9
Distance traveled after self-admin2.02.36.8-2.12.1-1.0-0.8-2.62.1-1.51.70.21.6-2.4-1.71.71.4-1.3-1.5-1.41.50.8-1.00.50.6-0.71.31.0
Extensor digitorum longus weight0.62.65.2-1.11.1-1.9-0.7-1.61.6-1.71.8-0.21.70.4-1.91.92.3-1.8-2.0-1.81.61.7-1.9-0.62.3-2.2-0.20.5
Bone: elastic displacement0.50.61.80.4-0.4-0.4-0.80.8-0.81.0-1.01.3-0.5-0.40.5-0.5-0.60.40.40.5-0.3-1.10.91.2-1.01.00.80.8
Bone: elastic work4.15.213.02.7-2.7-0.3-1.92.4-2.33.2-2.93.6-1.6-0.21.9-1.9-2.01.41.81.5-1.4-3.32.93.2-2.72.71.50.5
Bone: endosteal estimation1.12.46.7-1.71.7-1.3-0.6-1.81.7-1.81.7-0.51.0-0.9-1.81.81.8-1.5-1.6-1.61.11.6-1.9-0.72.5-2.6-0.10.4
Bone: endosteal perimeter0.40.82.3-1.01.0-0.8-1.0-1.00.9-0.50.40.90.6-1.5-1.01.00.5-0.7-0.9-0.80.7-0.1-0.40.81.0-1.11.01.5
Epididymis fat weight0.20.61.9-0.50.5-1.4-1.2-0.70.7-0.50.90.80.6-0.5-0.50.51.2-1.0-0.6-1.00.60.6-0.80.40.8-0.80.0-0.0
Delta time in closed arm before/after self-admin0.30.31.6-0.40.4-0.6-0.1-0.30.3-0.50.7-0.31.20.3-0.60.60.3-0.5-0.6-0.51.00.3-0.3-0.30.10.0-0.20.5
Delta time in open arm before/after self-admin0.00.00.3-0.20.20.1-0.1-0.2-0.1-0.20.2-0.3-0.3-0.5-0.30.3-0.10.0-0.10.0-0.00.2-0.1-0.2-0.10.1-0.0-0.2
Diff in mean of infusions in LGA sessions0.30.31.3-0.40.40.81.2-0.10.1-0.10.0-0.8-0.30.1-0.50.5-0.40.9-0.40.8-0.50.10.0-0.50.1-0.2-0.6-0.8
Delay discount exponential model param0.80.83.2-0.50.5-1.1-1.4-0.70.7-0.30.51.60.7-1.5-0.50.51.1-0.7-0.7-0.70.9-0.3-0.11.40.3-0.31.80.9
Extinction: sum of active levers before priming2.72.75.11.8-1.82.01.92.1-2.31.4-1.5-0.7-2.01.21.9-1.9-1.52.11.82.1-1.8-0.91.3-0.7-1.11.2-0.7-1.9
Active lever presses in extinction session 64.34.27.82.3-2.31.91.12.2-2.31.9-2.1-0.9-2.82.02.5-2.5-2.72.12.22.1-2.7-1.01.3-0.8-1.41.3-2.3-2.3
Bone: final force2.43.914.73.8-3.8-1.8-2.22.2-2.12.5-2.22.6-2.02.02.1-2.1-1.20.21.80.4-1.3-1.51.11.5-0.70.8-1.00.1
Bone: final moment2.64.215.23.9-3.9-1.8-2.42.2-2.22.7-2.42.9-2.01.72.2-2.2-1.30.41.80.5-1.4-1.91.41.9-0.91.0-0.60.2
Food consumed during 24 hour testing period0.50.72.0-0.70.7-0.1-0.9-1.21.1-0.50.70.61.4-0.8-0.90.90.6-0.8-1.0-0.81.0-0.0-0.10.70.1-0.11.11.0
Glucose6.710.117.43.0-3.04.22.33.8-3.83.1-3.3-0.4-4.21.93.5-3.5-3.34.03.94.0-4.1-2.42.9-0.1-2.52.4-1.0-3.6
Heart weight0.91.33.92.0-2.0-0.4-0.81.4-1.41.1-1.01.4-1.80.21.6-1.60.20.61.40.7-1.1-0.70.50.70.0-0.00.3-1.1
Delay discount hyperbolic model param0.80.83.1-0.50.5-1.1-1.4-0.70.7-0.30.61.60.8-1.5-0.60.61.1-0.7-0.7-0.70.8-0.3-0.11.40.3-0.31.70.8
Intermittent access intake day 1-15 change1.01.03.1-1.31.3-0.6-1.0-1.71.7-0.40.60.41.3-1.8-1.21.2-0.2-0.8-0.9-0.90.8-0.20.00.9-0.50.40.71.1
Intermittent access intake escalation1.41.44.5-1.61.6-0.8-1.0-2.12.1-0.81.00.21.5-1.8-1.51.50.3-1.1-1.3-1.21.00.3-0.50.60.0-0.10.60.9
Intermittent access intake escalation 20.60.62.6-0.30.3-0.2-1.1-0.60.60.6-0.41.0-0.2-1.6-0.20.2-0.90.2-0.00.1-0.4-1.00.91.4-1.21.10.90.1
Intermitt. access day 1 inactive lever presses0.20.21.0-0.10.10.1-1.00.2-0.30.5-0.30.7-0.2-0.60.0-0.0-0.7-0.1-0.1-0.1-0.1-0.70.60.8-0.80.80.00.2
Intermitt. access day 15 inactive lever presses0.60.73.2-0.50.5-1.1-1.0-0.70.7-0.60.50.20.6-0.8-1.01.00.2-1.1-1.1-1.11.00.4-0.60.30.4-0.40.11.8
Intermitt. access escalation Index2.72.46.3-1.81.8-1.4-1.2-1.71.7-1.41.60.42.5-1.4-1.81.81.4-1.8-1.6-1.92.10.7-1.00.40.9-0.91.01.9
Intermittent access day 1 total infusions0.20.20.8-0.10.1-0.6-0.90.1-0.1-0.20.30.7-0.1-0.1-0.60.60.9-0.7-0.7-0.60.20.2-0.30.40.5-0.50.3-0.0
Intermittent access day 15 total infusions0.91.02.0-1.11.1-1.0-1.2-1.31.3-0.81.00.51.1-1.3-1.41.40.8-1.3-1.4-1.31.00.4-0.60.60.3-0.40.70.8
Intermittent access terminal intake (last 3 days)1.01.12.6-1.21.2-1.0-1.3-1.21.3-0.50.80.81.1-1.6-1.51.50.5-1.1-1.5-1.10.9-0.1-0.21.0-0.10.11.10.9
Intermittent access total infusions0.60.71.4-0.80.8-0.9-1.1-0.80.9-0.60.70.50.9-0.7-1.11.10.7-1.2-1.2-1.10.80.3-0.50.50.3-0.30.40.8
Intermittent access day 1 locomotion0.20.20.8-0.00.0-0.7-0.80.2-0.1-0.30.4-0.2-0.10.5-0.20.20.2-0.7-0.6-0.50.30.5-0.6-0.30.3-0.3-0.90.3
Intermittent access day 15 total locomotion0.10.20.7-0.30.3-0.4-0.8-0.30.4-0.00.00.40.0-0.7-0.40.4-0.2-0.5-0.5-0.40.2-0.1-0.00.5-0.10.10.20.9
Intermittent access total locomotion0.10.10.8-0.00.0-0.5-0.9-0.10.2-0.10.10.0-0.10.1-0.20.2-0.2-0.6-0.4-0.50.20.2-0.30.0-0.00.0-0.60.5
Intermittent access standard deviation2.02.15.31.2-1.21.61.11.1-1.11.5-1.6-0.6-1.91.31.3-1.3-2.31.71.31.7-2.0-1.01.4-0.2-1.71.7-1.4-1.5
Left kidney weight1.02.87.92.8-2.80.30.12.1-2.11.7-1.80.6-2.02.12.5-2.5-0.91.22.31.3-1.8-0.90.8-0.1-0.00.0-1.2-1.4
Right kidney weight0.92.67.52.6-2.60.10.12.0-2.01.5-1.60.1-1.72.72.4-2.4-0.80.92.41.0-1.6-0.40.5-0.60.00.0-1.8-1.2
Cocaine induced anxiety3.64.19.41.7-1.70.8-1.22.1-2.02.8-2.42.2-1.8-0.21.7-1.7-2.91.51.51.4-1.6-3.02.82.4-3.13.00.7-0.3
Post-drug Anxiety1.82.06.21.3-1.30.9-0.21.7-1.71.9-1.70.6-1.40.51.3-1.3-2.51.11.21.1-1.2-1.81.80.9-2.12.1-0.5-0.2
Baseline Anxiety1.71.88.3-0.00.00.82.2-0.10.1-1.20.6-2.90.01.80.0-0.00.50.00.20.10.02.0-1.5-2.91.7-1.7-2.3-0.3
Tail length3.410.322.9-3.33.3-4.3-4.8-3.53.6-2.33.02.73.0-4.4-3.23.23.0-4.0-3.2-4.03.41.0-2.02.51.8-1.92.63.2
Length with tail0.31.08.10.4-0.4-1.5-2.80.1-0.10.8-0.52.3-0.3-0.60.5-0.50.0-0.70.2-0.6-0.1-0.90.41.9-0.0-0.00.50.8
Length without tail5.010.918.04.2-4.22.41.24.2-4.23.6-3.80.1-3.84.04.2-4.2-3.33.54.03.5-3.9-2.32.6-0.2-2.02.0-2.4-2.9
Times rat made contact with spout1.61.911.8-1.41.40.7-1.5-0.80.70.10.21.90.7-3.3-0.80.80.4-0.0-0.7-0.00.5-1.41.12.4-1.00.93.40.6
Lifetime Intake0.30.41.1-0.70.7-0.5-0.6-0.70.7-0.50.60.20.8-0.4-1.01.00.5-0.9-1.0-0.80.60.2-0.30.30.1-0.10.30.4
Liver weight, left1.32.15.51.1-1.11.40.61.7-1.71.4-1.50.3-2.30.82.1-2.1-1.01.81.91.8-2.2-1.01.10.2-0.70.7-0.4-2.2
Liver weight, right0.20.32.10.1-0.1-0.8-1.50.3-0.20.4-0.21.3-0.6-0.1-0.00.00.3-0.2-0.1-0.2-0.3-0.3-0.00.90.3-0.30.2-0.3
Locomotor activity0.40.63.60.5-0.50.71.90.3-0.3-0.1-0.1-1.0-0.80.90.4-0.4-0.10.80.10.8-0.90.5-0.2-1.00.4-0.4-0.9-1.4
Locomotor testing distance0.40.74.7-0.20.20.42.2-0.20.1-0.70.4-1.4-0.20.90.1-0.10.50.4-0.20.3-0.31.1-0.9-1.51.3-1.3-1.1-0.8
Locomotor testing rearing0.50.71.8-1.11.1-0.11.0-1.31.3-1.11.1-1.10.9-0.4-1.01.00.6-0.3-1.1-0.40.60.9-0.8-0.80.6-0.6-0.2-0.0
Locomotion in novel chamber0.10.10.50.1-0.10.20.4-0.30.3-0.20.1-0.50.70.6-0.00.0-0.0-0.1-0.1-0.10.20.3-0.3-0.60.6-0.6-0.70.3
Locomotion in novel chamber post-restriction1.21.54.0-0.80.8-1.3-2.0-1.41.5-0.30.71.71.6-1.6-1.31.30.9-1.3-1.4-1.31.1-0.3-0.11.60.2-0.21.51.1
Fecal boli incidents, locomotor time 10.40.41.4-0.10.10.20.5-0.20.4-0.80.6-0.6-0.00.1-0.70.71.2-0.1-0.7-0.2-0.11.0-0.9-0.81.1-1.10.0-0.9
Change in fecal boli incidents, locomotor task1.31.22.90.4-0.41.71.60.4-0.71.0-0.9-0.7-0.80.80.6-0.6-1.61.60.81.6-1.4-0.91.3-0.2-1.51.4-0.5-1.7
Time >=10cm from walls, locomotor time 12.52.57.0-1.81.8-1.7-1.4-2.12.1-1.41.5-0.12.4-1.2-1.51.50.8-2.0-1.6-2.02.20.9-1.20.00.9-0.80.32.7
Bouts of movement, locomotor time 10.60.74.00.6-0.61.42.00.9-0.90.2-0.4-0.7-0.91.00.6-0.60.01.10.11.1-0.90.10.2-0.70.0-0.0-0.2-1.3
Total resting periods, locomotor time 10.80.84.50.7-0.71.62.11.0-1.00.4-0.6-0.7-1.01.10.7-0.7-0.21.20.21.2-1.0-0.10.4-0.7-0.20.2-0.2-1.4
Rest time, locomotor task time 10.30.31.60.3-0.31.00.90.3-0.40.3-0.40.1-1.30.00.2-0.20.10.80.00.8-0.9-0.30.30.1-0.10.00.5-1.1
Distance moved, locomotor task time 10.40.41.4-0.50.5-1.0-0.9-0.60.5-0.30.5-0.51.10.1-0.60.6-0.7-0.8-0.3-0.80.80.3-0.3-0.3-0.20.3-1.20.9
Vertical activity count, locomotor time 10.50.61.8-0.60.6-1.4-0.9-0.70.6-0.70.8-0.10.9-0.3-0.50.50.2-1.1-0.6-1.11.10.6-0.8-0.10.5-0.4-0.61.1
Time >=10cm from walls, locomotor time 20.20.20.70.7-0.7-0.7-0.50.3-0.50.3-0.40.5-0.10.60.6-0.60.2-0.30.4-0.20.3-0.20.10.20.00.00.20.8
Bouts of movement, locomotor time 20.40.42.2-0.00.00.71.10.2-0.3-0.30.3-1.20.11.40.0-0.0-0.00.3-0.00.3-0.10.7-0.5-1.20.5-0.5-1.5-0.8
Total resting periods, locomotor time 20.50.51.6-0.40.40.30.8-0.30.2-0.80.7-1.10.51.1-0.40.40.6-0.2-0.4-0.20.31.0-0.9-1.21.0-1.0-1.3-0.4
Rest time, locomotor task time 20.70.71.6-1.21.20.40.6-1.31.2-0.90.9-0.00.8-0.7-1.31.31.1-0.3-1.2-0.40.40.5-0.60.10.9-1.00.7-0.3
Distance moved, locomotor task time 20.60.71.81.1-1.1-0.5-0.21.2-1.30.7-0.6-0.2-0.81.41.1-1.1-0.90.31.10.4-0.3-0.20.4-0.3-0.80.9-1.2-0.1
Vertical activity count, locomotor time 20.50.62.01.0-1.0-1.2-0.40.8-0.9-0.10.1-0.4-1.01.20.9-0.90.3-0.30.8-0.2-0.10.8-0.8-0.80.7-0.6-1.4-0.4
Light reinforcement 11.12.04.9-1.61.6-1.8-1.3-1.51.5-1.21.60.92.2-1.4-1.21.21.6-1.6-1.4-1.72.20.5-0.80.80.6-0.61.41.5
Light reinforcement 20.50.72.9-0.60.6-1.7-1.2-0.60.6-0.40.81.21.0-0.8-0.70.71.0-1.1-0.7-1.11.10.0-0.40.90.3-0.30.90.7
Bone: marrow area1.02.26.5-1.61.6-1.3-0.6-1.81.6-1.81.7-0.60.9-0.9-1.71.71.7-1.4-1.5-1.51.01.6-1.8-0.72.5-2.5-0.20.3
Bone: maximum diameter0.40.72.91.7-1.7-1.4-0.90.5-0.50.9-1.01.2-0.70.71.2-1.2-0.4-0.10.8-0.1-0.5-0.50.20.60.4-0.4-0.50.6
Bone: maximum force2.03.412.83.6-3.6-2.2-2.41.9-1.92.2-1.92.8-1.81.91.9-1.9-0.7-0.01.50.1-1.1-1.30.81.6-0.30.3-0.90.1
Bone: maximum moment2.13.612.93.6-3.6-2.1-2.61.9-1.92.4-2.13.1-1.81.51.9-1.9-0.80.11.50.2-1.2-1.71.12.0-0.50.5-0.50.2
Mean time between licks in bursts0.40.52.90.1-0.10.31.50.2-0.1-0.40.2-1.7-0.01.00.3-0.3-0.30.20.30.2-0.20.8-0.4-1.60.2-0.2-1.4-0.7
Mean num. licks in bursts0.50.62.6-0.20.21.1-0.50.0-0.10.6-0.51.1-0.3-1.4-0.00.0-0.40.60.30.6-0.4-1.21.01.3-0.80.81.60.0
Cd content in liver0.80.93.41.1-1.10.71.20.7-0.60.1-0.2-1.4-0.61.80.9-0.9-0.30.50.90.5-0.70.6-0.3-1.50.1-0.1-1.7-1.4
Co content in liver0.20.20.5-0.10.10.50.5-0.60.5-0.60.5-0.70.4-0.1-0.40.40.2-0.3-0.2-0.30.20.5-0.5-0.60.6-0.7-0.3-0.0
Cu content in liver0.81.02.20.7-0.71.4-0.10.8-0.81.3-1.30.7-0.70.20.7-0.7-1.31.00.91.0-0.9-1.31.40.9-1.51.50.5-0.2
Fe content in liver0.50.62.3-0.60.60.31.2-0.70.7-0.90.6-1.50.00.2-0.30.30.20.1-0.50.0-0.11.0-0.9-1.31.1-1.1-1.0-0.3
K content in liver2.72.65.3-1.61.6-1.8-1.6-1.91.9-1.41.70.52.0-1.8-2.32.31.4-2.1-1.9-2.12.10.8-1.10.60.6-0.61.11.8
Mg content in liver3.33.45.7-1.91.9-2.0-0.8-2.22.2-2.22.3-0.62.2-1.6-2.22.21.9-2.4-2.1-2.42.31.8-1.9-0.61.2-1.20.21.3
Mn content in liver0.20.20.70.8-0.8-0.2-0.50.5-0.50.5-0.40.5-0.5-0.10.2-0.2-0.30.00.40.1-0.2-0.30.40.4-0.70.70.0-0.1
Na content in liver0.10.10.3-0.40.40.30.1-0.20.1-0.10.1-0.30.2-0.1-0.20.2-0.3-0.1-0.3-0.10.2-0.00.1-0.0-0.20.2-0.00.6
Rb content in liver0.60.73.0-0.30.3-1.7-1.4-0.60.6-0.50.60.60.7-0.2-1.01.00.8-1.4-0.5-1.31.10.5-0.70.40.4-0.40.41.3
Se content in liver0.91.25.2-1.51.5-0.8-1.0-1.11.1-0.81.00.41.4-2.3-0.70.70.5-1.1-1.1-1.01.40.1-0.20.7-0.30.31.41.4
Sr content in liver1.81.63.41.1-1.11.60.51.1-1.11.5-1.70.7-0.9-0.31.0-1.0-1.61.61.21.6-1.3-1.71.91.0-1.71.70.9-0.3
Zn content in liver0.10.10.3-0.30.30.20.1-0.40.4-0.30.2-0.40.20.2-0.40.40.1-0.2-0.2-0.20.00.3-0.4-0.30.5-0.5-0.4-0.1
Bone: minimum diameter0.61.04.41.5-1.5-1.4-1.80.3-0.31.1-1.02.1-0.0-0.30.7-0.7-0.5-0.30.5-0.3-0.0-1.20.71.7-0.30.30.71.4
Time in familiar zone, hab. session 10.60.61.10.9-0.90.3-0.21.0-1.00.9-0.70.4-0.90.41.0-1.0-0.60.71.00.7-0.8-0.70.80.3-0.90.9-0.0-0.9
Time in novel zone, hab. session 10.20.20.7-0.70.7-0.00.1-0.60.6-0.40.4-0.20.8-0.1-0.60.60.3-0.4-0.6-0.50.60.3-0.3-0.10.1-0.10.20.6
Total zone transitions, hab. session 10.20.31.20.5-0.5-0.20.50.4-0.4-0.1-0.0-0.6-0.61.10.9-0.90.20.20.60.3-0.30.5-0.4-0.80.2-0.2-0.7-0.7
Total locomotion distance, hab. session 10.20.31.4-0.10.1-1.0-0.4-0.10.1-0.50.50.1-0.10.40.3-0.31.2-0.6-0.1-0.50.30.8-0.8-0.30.9-0.9-0.0-0.2
Locomotion velocity, hab. session 10.30.41.9-0.10.1-1.0-0.3-0.30.3-0.70.60.1-0.10.20.2-0.21.4-0.6-0.2-0.60.30.9-1.0-0.31.2-1.20.0-0.2
Time in familiar zone, hab. session 20.20.20.5-0.30.30.20.3-0.60.6-0.60.7-0.60.70.2-0.20.20.5-0.3-0.3-0.40.30.5-0.5-0.50.4-0.4-0.2-0.5
Time in novel zone, hab. session 20.20.20.50.5-0.5-0.20.30.7-0.70.5-0.6-0.1-0.70.60.4-0.4-0.60.30.60.4-0.3-0.20.2-0.2-0.30.3-0.50.2
Total zone transitions, hab. session 20.81.12.9-0.20.2-1.50.0-0.70.7-1.31.3-0.60.80.4-0.10.11.7-1.4-0.4-1.31.21.6-1.6-1.01.5-1.5-0.50.3
Total locomotion distance, hab. session 21.72.26.0-1.11.1-2.4-0.8-1.31.3-1.71.90.11.4-0.4-0.90.92.5-2.0-1.4-1.91.81.7-1.9-0.41.9-1.80.30.8
Locomotion velocity, hab. session 21.52.16.1-1.01.0-2.5-1.0-1.21.3-1.61.70.31.4-0.5-0.80.82.4-2.0-1.3-1.91.81.5-1.8-0.21.8-1.70.30.9
Novel to familiar place preference ratio1.51.54.20.9-0.9-0.0-1.51.1-1.11.7-1.52.0-0.8-0.40.9-0.9-1.20.80.90.8-0.7-1.91.72.0-1.61.61.10.4
Novelty place preference1.61.64.21.0-1.00.1-1.41.2-1.11.8-1.52.0-0.8-0.30.9-0.9-1.20.80.90.9-0.7-2.01.72.0-1.61.61.00.4
Time in novel zone, NPP test1.21.33.40.9-0.9-0.1-1.31.0-1.01.6-1.31.8-0.7-0.30.9-0.9-1.10.70.90.8-0.6-1.71.51.7-1.51.50.90.3
Total zone transitions, NPP test2.02.85.7-1.41.4-1.80.3-1.51.5-2.22.0-1.41.40.5-1.31.32.0-1.8-1.5-1.81.72.4-2.4-1.72.3-2.3-1.00.9
Total locomotion distance, NPP test2.63.57.4-1.81.8-2.4-0.5-1.71.8-2.42.4-0.81.50.1-1.51.52.7-2.3-1.8-2.22.02.4-2.6-1.22.5-2.5-0.40.7
Locomotion velocity, NPP test1.92.75.7-1.61.6-2.2-0.6-1.51.6-2.02.0-0.41.40.2-1.41.42.4-2.0-1.7-1.91.72.0-2.2-0.82.2-2.1-0.20.8
Intraocular pressure0.81.13.4-0.90.9-1.8-1.1-1.51.4-0.90.90.61.1-1.0-0.80.81.0-1.2-0.8-1.30.90.6-1.00.41.2-1.20.41.1
Delta distance traveled before/after self-admin2.22.34.8-2.12.1-1.00.2-2.22.2-1.92.1-1.02.0-0.9-1.51.51.7-1.4-1.5-1.41.61.6-1.6-0.91.2-1.20.10.1
Delta ambulatory time before/after self-admin2.62.86.0-2.22.2-0.70.7-2.42.5-2.22.4-1.42.2-0.7-1.71.71.9-1.3-1.6-1.41.61.8-1.7-1.21.4-1.40.0-0.2
Parametrial fat weight0.51.14.9-0.60.6-1.2-2.2-0.70.6-0.10.81.80.7-1.4-0.80.81.4-1.0-0.7-1.00.6-0.30.01.6-0.20.21.7-0.6
Pavlov. Cond. lever latency1.11.43.4-0.40.4-0.60.8-0.70.8-1.41.2-1.60.51.2-0.70.70.9-1.0-0.8-1.00.71.9-1.8-1.81.8-1.7-1.70.3
Pavlov. Cond. magazine entry latency1.41.85.00.8-0.80.2-1.60.5-0.51.6-1.32.0-0.2-1.71.1-1.1-1.30.71.00.7-0.5-2.11.92.2-2.02.01.60.4
Pavlov. Cond. change in total contacts1.41.52.61.0-1.01.1-0.41.2-1.21.5-1.40.9-1.3-0.51.2-1.2-1.21.31.51.3-1.4-1.51.61.0-1.61.60.6-1.1
Pavlov. Cond. index score1.11.45.30.3-0.3-0.3-1.90.1-0.21.2-0.82.20.1-1.90.6-0.6-0.60.30.50.3-0.1-1.81.52.3-1.51.52.00.5
Pavlov. Cond. latency score1.11.45.10.3-0.30.1-1.60.3-0.31.2-0.92.1-0.1-1.90.6-0.6-0.60.50.50.5-0.4-1.91.62.2-1.61.62.00.2
Pavlov. Cond. lever contacts0.30.41.4-0.10.1-0.0-0.80.0-0.10.6-0.41.1-0.0-1.10.2-0.2-0.20.30.20.3-0.2-0.90.81.2-0.80.81.2-0.1
Pavlov. Cond. magazine entry number2.32.86.2-1.31.3-0.81.4-1.01.0-2.11.8-2.20.91.7-1.61.61.6-1.3-1.6-1.31.32.5-2.3-2.42.3-2.3-1.70.4
Pavlov. Cond. intertrial magazine entries0.91.12.2-0.80.8-1.5-1.0-1.01.0-1.11.30.21.0-0.9-1.21.21.4-1.4-1.2-1.41.20.9-1.10.01.0-1.00.40.5
Pavlov. Cond. lever-magazine prob. diff.1.21.55.10.5-0.5-0.3-1.90.3-0.41.3-1.02.2-0.1-1.60.8-0.8-0.80.40.70.4-0.2-1.91.62.3-1.71.61.70.6
Pavlov. Cond. response bias1.61.94.40.9-0.90.4-1.30.8-0.81.7-1.41.9-0.7-1.31.3-1.3-1.31.01.21.0-0.9-2.11.92.0-2.02.01.4-0.2
Pavlov. Cond. lever latency0.91.22.41.0-1.01.60.61.1-1.11.2-1.3-0.4-0.90.81.2-1.2-1.51.31.41.3-1.3-0.91.2-0.2-1.31.4-0.6-0.9
Pavlov. Cond. magazine entry latency1.41.73.9-1.21.2-0.21.9-0.90.9-1.71.6-1.80.20.5-1.11.11.4-0.6-1.2-0.60.62.0-1.8-1.81.6-1.7-1.1-0.8
Pavlov. Cond. change in total contacts0.60.82.2-0.90.9-0.60.4-0.70.7-1.11.0-0.80.40.2-0.90.90.9-0.7-0.9-0.70.71.2-1.3-0.91.5-1.5-0.60.4
Pavlov. Cond. index score0.81.02.3-1.11.1-0.70.6-0.90.8-1.41.4-0.70.3-0.3-1.01.01.4-0.8-1.2-0.90.71.4-1.4-0.81.5-1.5-0.2-0.1
Pavlov. Cond. latency score1.01.22.7-1.21.2-0.90.6-1.00.9-1.51.5-0.70.5-0.4-1.11.11.5-1.0-1.2-1.00.91.5-1.5-0.81.6-1.6-0.20.1
Pavlov. Cond. lever contacts1.41.93.3-1.21.2-1.8-0.8-1.51.5-1.51.60.51.3-1.2-1.51.51.7-1.7-1.7-1.71.71.0-1.40.31.5-1.50.91.4
Pavlov. Cond. magazine entry number1.51.84.11.4-1.40.4-1.60.9-0.91.8-1.71.8-0.3-0.61.2-1.2-1.40.81.40.8-0.7-2.01.81.8-1.61.71.10.6
Pavlov. Cond. intertrial magazine entries0.60.74.70.4-0.4-1.4-2.2-0.40.40.3-0.21.40.7-0.7-0.00.0-0.0-0.9-0.0-0.80.7-0.60.21.3-0.30.30.81.7
Pavlov. Cond. lever-magazine prob. diff.0.91.22.4-1.21.2-0.70.7-0.90.9-1.51.4-0.90.3-0.2-1.21.21.4-0.8-1.3-0.90.71.5-1.5-0.91.5-1.6-0.3-0.2
Pavlov. Cond. response bias0.81.22.3-1.11.1-1.20.2-1.11.1-1.31.4-0.30.7-0.3-1.31.31.4-1.1-1.5-1.11.01.2-1.3-0.41.3-1.3-0.10.4
Time in closed arm before self-admin0.91.03.11.2-1.21.00.51.0-1.11.1-1.40.1-1.80.71.1-1.1-1.21.10.91.2-1.5-0.70.80.1-0.70.7-0.5-0.9
Time in closed arm after self-admin1.51.53.41.2-1.21.50.91.3-1.31.4-1.4-0.3-1.31.20.9-0.9-1.81.40.61.5-1.5-1.11.40.0-1.51.5-0.8-1.0
Time in open arm before self-admin0.40.42.2-0.50.5-0.50.2-0.50.5-0.70.7-0.01.50.1-0.50.51.1-0.6-0.7-0.61.00.4-0.5-0.20.8-0.80.50.6
Time in open arm after self-admin0.10.10.5-0.00.0-0.30.1-0.2-0.1-0.50.5-0.40.4-0.1-0.30.30.6-0.3-0.0-0.30.50.5-0.5-0.60.7-0.7-0.10.0
Bone: periosteal estimation0.40.84.01.5-1.5-2.0-1.60.2-0.30.7-0.61.5-0.60.60.6-0.60.2-0.60.4-0.5-0.3-0.3-0.20.71.0-1.0-0.50.5
Bone: periosteal perimeter1.42.35.62.2-2.2-0.6-1.41.5-1.52.1-2.02.4-1.40.21.9-1.9-1.30.81.50.8-1.2-2.01.51.9-0.80.80.40.4
Bone: post-yield work0.30.41.1-0.10.1-1.0-0.3-0.20.2-0.50.4-0.50.31.0-0.30.30.3-0.7-0.2-0.70.40.7-0.8-0.71.0-1.0-1.00.5
Progressive ratio test 1 active lever presses1.01.02.2-1.11.1-0.9-1.1-1.31.4-0.70.80.51.2-1.1-1.41.40.6-1.2-1.5-1.21.10.2-0.50.60.5-0.50.61.3
Progressive ratio test 1 breakpoint1.21.22.6-1.21.2-1.0-1.3-1.31.3-0.70.80.91.2-1.4-1.41.40.8-1.2-1.6-1.21.20.1-0.50.90.5-0.51.01.4
Progressive ratio test 1 inactive lever presses0.60.62.8-0.40.4-1.2-1.7-0.60.6-0.10.40.90.9-0.6-0.70.70.0-1.2-1.0-1.11.0-0.1-0.10.9-0.30.30.31.3
Progressive ratio test 2 active lever presses0.40.51.1-0.70.7-0.6-0.8-0.80.9-0.50.60.50.5-1.0-0.90.90.6-0.8-1.0-0.80.60.1-0.30.60.3-0.30.60.4
Progressive ratio test 2 breakpoint0.80.81.6-1.01.0-1.0-1.0-1.11.1-0.80.90.50.9-1.1-1.21.20.9-1.2-1.3-1.11.00.4-0.70.50.6-0.60.60.7
Progressive ratio test 2 inactive lever presses0.10.10.40.2-0.2-0.3-0.60.1-0.10.3-0.20.4-0.0-0.3-0.10.1-0.6-0.2-0.2-0.20.1-0.50.30.5-0.50.5-0.10.5
Incentive Sensitization - Responses0.60.61.9-0.90.9-0.7-0.7-0.80.9-0.50.70.80.7-1.4-0.90.90.9-0.8-0.9-0.70.70.1-0.30.80.3-0.31.30.4
Incentive Sensitization - Breakpoint0.50.51.9-0.90.9-0.5-0.6-0.70.8-0.40.60.80.5-1.4-0.80.80.8-0.6-0.8-0.60.6-0.0-0.20.80.2-0.21.30.4
Sum of active levers in priming session hrs 5-60.70.72.40.5-0.50.3-0.71.0-1.11.0-0.60.8-1.3-0.50.5-0.5-0.90.60.60.6-1.1-1.00.90.8-1.01.00.1-1.5
Progressive ratio0.40.41.40.4-0.40.60.60.6-0.4-0.2-0.0-0.8-1.10.60.1-0.10.10.5-0.10.4-0.80.6-0.5-1.01.0-1.1-1.0-1.2
Food seeking constrained by brief footshock0.20.21.5-0.10.11.20.40.3-0.20.4-0.6-0.0-0.4-0.2-0.10.1-0.60.7-0.20.7-0.5-0.60.70.3-0.60.60.4-0.1
Seeking ratio, punishment vs. effort0.30.41.9-0.80.8-0.3-0.5-0.70.5-0.10.20.51.1-0.7-0.50.50.0-0.6-0.3-0.50.9-0.30.30.7-0.60.61.01.4
Retroperitoneal fat weight1.34.214.1-1.51.5-2.3-3.8-2.12.1-0.81.33.11.3-3.2-2.02.02.3-2.1-2.1-2.11.4-0.0-0.82.71.2-1.32.61.4
Reaction time number correct2.94.28.5-1.21.2-2.9-0.6-2.32.2-2.42.4-1.22.50.3-1.51.52.1-2.7-1.7-2.62.62.5-2.7-1.52.3-2.3-1.01.9
Reaction time mean minus median0.30.41.80.1-0.11.10.9-0.10.10.4-0.4-0.0-0.40.1-0.30.3-0.41.0-0.11.0-1.0-0.50.70.2-0.60.50.4-1.3
Reaction time mean minus median AUC0.10.10.30.0-0.00.30.5-0.20.20.2-0.20.10.00.1-0.60.6-0.10.4-0.40.4-0.4-0.20.30.2-0.20.20.2-0.5
Reaction time num false alarms0.10.10.4-0.10.10.50.4-0.1-0.0-0.20.1-0.2-0.10.20.5-0.50.30.30.40.3-0.10.1-0.2-0.30.6-0.60.2-0.3
Reaction time num false alarms AUC0.20.20.7-0.30.30.40.8-0.20.1-0.50.4-0.7-0.10.30.4-0.40.50.20.30.20.00.5-0.5-0.70.8-0.8-0.1-0.4
Reaction time trials correct on left2.94.28.5-1.21.2-2.9-0.6-2.32.2-2.42.4-1.22.50.3-1.51.52.1-2.7-1.7-2.62.62.5-2.7-1.52.3-2.3-1.01.9
Reaction time trials on left3.14.48.7-1.31.3-3.0-0.6-2.42.3-2.52.5-1.22.60.3-1.61.62.2-2.7-1.8-2.72.62.6-2.7-1.62.4-2.3-1.11.9
Reaction time mean0.20.30.9-0.20.2-0.5-0.6-0.70.7-0.20.40.60.5-0.5-0.90.90.6-0.2-0.8-0.20.2-0.0-0.10.50.1-0.20.7-0.2
Reaction time mean AUC0.40.51.6-0.50.5-0.8-0.5-1.11.1-0.60.70.30.7-0.4-1.31.31.1-0.6-1.2-0.60.50.5-0.60.20.7-0.70.60.0
Median of all reaction times0.20.30.7-0.10.1-0.8-0.8-0.60.6-0.20.40.50.6-0.3-0.80.80.6-0.4-0.7-0.40.40.1-0.20.30.2-0.20.50.1
Reaction time omissions0.70.92.7-0.90.9-0.60.3-1.61.6-1.01.1-0.31.3-0.7-1.41.40.8-0.7-1.6-0.80.90.7-0.7-0.20.5-0.50.30.4
Reaction time false alarm rate0.70.93.40.3-0.31.80.90.9-1.00.8-0.90.0-1.3-0.01.0-1.0-0.61.51.11.5-1.2-0.81.00.2-0.40.40.5-1.2
Reaction time premature initiation rate0.10.11.10.1-0.10.41.1-0.10.0-0.20.2-0.80.10.3-0.00.00.00.30.20.3-0.10.3-0.0-0.7-0.00.0-0.3-0.7
Reaction time premature initiations1.01.42.8-0.70.7-1.30.6-1.31.3-1.61.5-1.41.40.4-0.90.91.2-1.2-0.8-1.21.31.7-1.6-1.41.3-1.3-0.80.3
Std. dev. reaction times0.20.20.7-0.20.20.50.8-0.70.7-0.30.3-0.50.10.1-0.80.80.40.3-0.70.3-0.30.3-0.2-0.40.3-0.30.2-0.8
Reaction time trials completed3.14.48.7-1.31.3-3.0-0.6-2.42.3-2.52.5-1.22.60.3-1.61.62.2-2.7-1.8-2.72.62.6-2.7-1.62.4-2.3-1.11.9
Reaction time trials AUC3.04.38.8-1.21.2-3.0-0.7-2.32.2-2.42.4-1.12.60.2-1.51.52.1-2.7-1.7-2.72.62.5-2.7-1.52.3-2.2-1.02.0
Run reversals in cocaine runway, females0.60.61.4-0.70.7-0.30.5-0.90.7-1.01.0-0.60.5-0.3-0.90.91.0-0.6-1.0-0.70.61.0-1.0-0.71.2-1.20.10.1
Run reversals in cocaine runway, males0.80.82.80.1-0.10.4-0.70.3-0.30.9-0.71.5-0.6-1.40.5-0.5-0.40.60.80.6-0.6-1.31.21.7-1.11.01.6-0.3
Latency to leave start box in cocaine runway0.60.72.4-0.90.9-0.30.3-0.60.7-1.11.1-0.50.1-0.3-0.70.71.5-0.4-0.8-0.40.21.2-1.2-0.71.4-1.40.1-0.8
Latency to leave start box in cocaine runway, F1.41.55.2-1.01.0-0.90.4-1.11.1-1.71.5-0.70.3-0.1-1.01.02.3-0.9-1.0-0.80.81.8-1.8-1.02.2-2.20.1-0.2
Latency to leave start box in cocaine runway, M0.10.10.6-0.60.60.0-0.5-0.20.2-0.10.40.30.3-0.6-0.30.30.2-0.1-0.4-0.2-0.0-0.10.10.4-0.10.10.2-0.8
Std. dev. time between licks in bursts2.53.06.5-1.21.2-2.5-0.9-1.91.9-1.91.9-0.72.0-0.0-1.61.61.6-2.5-1.6-2.42.12.0-2.2-0.91.8-1.7-0.91.8
Total sessions with >9 infusions0.20.20.80.1-0.10.00.4-0.00.0-0.30.3-0.70.00.80.0-0.00.3-0.3-0.3-0.2-0.10.6-0.5-0.80.6-0.6-0.9-0.5
Short access day 1 total inactive lever presses0.70.82.1-0.60.6-0.90.0-0.60.6-1.11.3-0.50.60.2-0.60.61.5-0.8-0.9-0.80.81.3-1.3-0.81.4-1.3-0.6-0.5
Short access day 10 total inactive lever presses0.60.73.80.2-0.2-1.0-2.00.4-0.30.8-0.31.6-0.1-0.50.0-0.0-0.7-0.4-0.1-0.30.3-1.00.71.5-1.21.20.30.6
Short access day 1 total infusions0.60.62.60.6-0.61.11.60.6-0.60.2-0.3-1.3-0.21.30.5-0.5-0.70.70.40.7-0.60.10.2-1.1-0.30.3-1.1-1.0
Short access day 10 total infusions0.40.41.7-0.70.7-0.1-0.8-0.50.6-0.10.30.60.6-0.9-1.21.20.0-0.7-1.3-0.60.3-0.30.10.8-0.20.20.70.4
Short access total infusions0.10.10.4-0.30.30.1-0.0-0.30.3-0.10.20.00.7-0.1-0.60.60.0-0.3-0.7-0.30.3-0.10.10.1-0.40.40.20.0
Short access day 1 locomotion0.90.91.61.1-1.10.90.81.2-1.11.0-1.1-0.3-0.91.01.2-1.2-1.31.11.01.2-1.0-0.70.9-0.3-0.91.0-0.6-0.7
Short access day 10 total locomotion1.11.23.01.0-1.01.00.41.3-1.31.3-1.2-0.1-1.10.91.0-1.0-1.61.00.81.2-1.0-1.01.30.2-1.71.7-0.5-0.6
Short access total locomotion0.80.81.40.9-0.90.90.61.1-1.20.9-1.0-0.3-0.91.11.0-1.0-1.20.90.71.0-0.9-0.60.9-0.2-1.01.1-0.7-0.5
One hour access (0.3 mA shock)1.21.43.1-1.41.4-1.3-1.7-0.91.0-0.81.11.10.8-1.8-1.41.41.2-1.4-1.3-1.31.30.3-0.61.00.4-0.41.31.0
Compulsive drug intake0.10.10.30.2-0.2-0.5-0.60.6-0.50.1-0.00.6-0.3-0.30.4-0.40.4-0.20.3-0.10.20.0-0.10.40.1-0.10.40.4
One hour access (shock baseline)1.21.42.6-1.51.5-0.8-0.8-1.41.4-1.11.30.31.2-1.0-1.61.61.5-1.3-1.5-1.31.20.7-0.90.30.9-1.00.80.6
Social response proportion0.60.65.30.8-0.8-0.10.60.2-0.2-0.0-0.1-1.40.11.80.2-0.2-0.80.10.20.1-0.30.6-0.5-1.40.3-0.3-2.3-0.4
Social responses0.40.54.80.6-0.60.11.00.1-0.10.1-0.2-1.00.52.20.3-0.3-0.60.00.30.00.00.4-0.2-1.10.00.0-1.80.1
Social time0.30.42.30.9-0.9-0.30.60.6-0.60.1-0.2-0.6-0.41.50.6-0.6-0.10.20.50.2-0.20.4-0.3-0.90.5-0.4-1.4-0.3
Soleus weight0.61.73.6-0.70.7-1.3-1.7-1.41.4-0.30.61.91.8-1.5-1.51.51.0-1.4-1.4-1.41.5-0.4-0.11.70.0-0.01.91.9
Bone: stiffness1.52.49.33.0-3.0-1.1-0.31.9-1.81.4-1.30.7-2.22.71.8-1.8-0.40.31.60.5-1.5-0.10.0-0.20.3-0.3-2.1-1.4
Tibialis anterior weight0.51.93.9-2.02.0-1.0-0.4-1.51.5-1.41.50.21.5-0.9-1.81.81.8-1.2-1.9-1.21.40.9-1.10.11.4-1.40.90.7
Time to tail flick, vehicle, before self-admin0.20.21.0-0.30.3-0.3-0.5-0.60.7-0.30.10.20.3-0.7-0.30.30.3-0.5-0.3-0.50.50.2-0.20.30.1-0.10.71.0
Time to tail flick, vehicle, after self-admin0.80.93.60.8-0.80.71.91.1-0.9-0.1-0.2-1.2-0.91.40.7-0.70.20.80.80.9-0.70.7-0.4-1.40.6-0.6-1.1-1.2
Time to tail flick, test, before self-admin0.10.10.8-0.40.4-0.2-0.4-0.80.9-0.20.3-0.10.1-0.4-0.30.3-0.0-0.4-0.3-0.3-0.10.2-0.20.1-0.40.4-0.3-0.3
Time to tail flick, test, after self-admin0.40.41.50.5-0.50.60.80.2-0.30.3-0.3-1.0-0.40.90.5-0.5-0.90.30.60.3-0.50.10.2-0.8-0.70.7-1.2-0.5
Delta time to tail flick, vehicle, before/after SA0.50.51.7-0.50.5-0.40.8-0.20.2-0.91.1-0.60.50.3-0.50.51.3-0.3-0.6-0.30.50.9-0.9-0.80.9-0.9-0.3-0.9
Delta time to tail flick, test, before/after SA2.11.93.61.7-1.71.01.11.8-1.91.3-1.3-0.4-1.51.51.7-1.7-1.41.41.91.4-1.4-0.81.0-0.5-0.80.9-1.0-1.4
Tibia length3.08.429.63.9-3.9-1.5-3.72.9-2.94.1-3.65.4-2.50.02.5-2.5-1.91.12.31.2-1.7-3.82.94.4-2.12.11.41.2
Ambulatory time before self-admin1.31.33.10.9-0.90.3-1.10.7-1.11.5-1.61.4-0.9-0.70.6-0.6-1.80.60.60.7-0.6-1.71.51.6-1.71.60.81.3
Ambulatory time after self-admin0.60.72.7-1.21.2-0.5-0.5-1.61.2-0.70.80.11.0-1.6-0.60.60.4-0.7-0.4-0.80.80.3-0.40.30.1-0.10.80.7
Bone: tissue strength0.40.42.30.7-0.7-1.5-0.6-0.40.4-0.10.10.40.10.80.0-0.00.5-0.8-0.4-0.80.30.5-0.8-0.11.0-1.0-0.80.7
Total heroin consumption4.04.711.52.7-2.71.50.92.6-2.92.2-2.30.0-3.41.72.9-2.9-2.12.32.92.3-2.8-1.21.3-0.2-0.80.7-1.7-2.2
Bone: trabecular number0.10.20.8-0.10.1-0.5-0.3-0.50.5-0.30.30.20.9-0.8-0.30.30.2-0.5-0.3-0.50.7-0.10.00.3-0.10.10.70.8
Bone: trabecular spacing2.02.65.5-1.41.4-2.0-0.3-1.51.5-1.91.9-0.91.10.1-1.51.51.8-1.9-1.6-1.91.52.2-2.3-1.22.3-2.3-1.10.9
Bone: trabecular thickness1.72.04.71.4-1.41.0-0.21.4-1.41.8-1.61.5-0.9-0.41.2-1.2-1.61.31.21.3-1.1-2.22.11.6-1.91.91.2-0.5
Bone: trabecular tissue density0.30.51.5-0.00.00.70.70.6-0.5-0.2-0.1-1.2-1.21.1-0.30.3-0.20.6-0.10.6-0.80.7-0.4-1.20.6-0.7-1.2-0.9
Water consumed over 24 hours0.30.41.50.1-0.11.20.20.2-0.30.5-0.50.40.2-0.40.2-0.2-0.50.70.30.6-0.2-1.01.00.7-0.90.91.10.1
Number of responses in last shaping day0.30.30.91.0-1.0-0.6-1.00.6-0.50.5-0.40.3-0.20.80.7-0.7-0.5-0.20.5-0.20.0-0.30.20.1-0.50.5-0.70.2