Hub : Genes

Vwa7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Vwa7 0.21 0.09 1.1e-10 0.09 0.11 0.09 0.1 1.4e-10 6.1e-12 3.3e-10 1.7e-11
2 pVTA gene expression Vwa7 0.31 0.1 0.0e+00 0.26 0.3 0.29 0.29 5.0e-21 3.7e-24 1.2e-23 3.5e-23
3 Adipose alternative TSS XM_063279117.1 0.03 0.02 5.4e-03 -0 0 -0 -0 6.9e-01 7.7e-02 9.6e-01 7.9e-01
4 PL gene expression Vwa7 0.05 0.03 4.3e-04 0.01 0.03 0.02 0.02 1.7e-02 3.1e-04 1.5e-03 1.5e-03
5 Brain alternative polyA XM_063279118.1 0.06 0.04 5.0e-05 0.04 0.03 0.03 0.03 7.8e-05 6.2e-04 1.8e-03 8.4e-04
6 pVTA alternative polyA NM_212499.2 0.06 0.03 3.0e-04 0.02 0.03 0.03 0.03 8.1e-03 1.5e-03 2.7e-03 1.3e-03
7 Eye gene expression Vwa7 0.62 0.15 2.9e-04 0.2 0.11 0.22 0.21 5.1e-04 8.2e-03 3.1e-04 3.4e-04
8 Brain intron excision ratio chr20_3802232_3802461 0.05 0.04 3.8e-03 0.01 0 -0 0 1.5e-02 2.7e-01 5.2e-01 1.8e-01
9 Brain gene expression Vwa7 0.34 0.13 0.0e+00 0.27 0.28 0.28 0.28 7.0e-25 8.4e-26 1.6e-26 1.1e-25
10 Brain alternative polyA XM_039098675.2 0.04 0.02 3.5e-03 0.01 0.01 -0 0 8.3e-02 3.0e-02 3.9e-01 1.1e-01
11 Adipose alternative TSS NM_212499.2 0.03 0.02 8.3e-03 0 0.01 0.03 0.01 9.5e-02 1.9e-02 2.8e-04 6.2e-02
12 NAcc gene expression Vwa7 0.03 0.02 9.7e-05 0.03 0.03 0.03 0.03 3.3e-05 6.2e-05 3.2e-05 8.9e-05
13 pVTA isoform ratio XR_010060676.1 0.07 0.04 4.6e-04 0.05 0.04 0.04 0.04 1.0e-04 2.4e-04 3.2e-04 3.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.91.53.31.81.40.21.4-0.5-1.61.7-1.7-0.21.10.01.40.3
Area under the delay curve0.20.30.9-0.5-0.6-0.2-0.60.20.9-0.50.8-0.4-0.10.0-0.2-0.6
BMI with tail1.44.811.22.02.12.32.62.6-1.91.4-1.32.8-2.4-1.21.03.3
BMI without tail1.64.812.01.11.52.81.63.5-1.20.9-0.73.2-3.3-2.11.22.5
Body weight1.04.516.5-0.00.62.11.23.40.0-0.20.93.3-4.1-1.0-0.73.3
Weight adjusted by age0.81.25.1-1.2-0.30.7-0.31.00.4-1.20.81.3-2.3-0.3-0.91.4
Bone surface0.10.10.4-0.3-0.4-0.3-0.20.00.4-0.60.4-0.10.00.2-0.50.0
Bone volume0.10.30.50.70.60.40.70.4-0.60.3-0.50.3-0.1-0.30.40.6
Breakpoint value in progressive ratio session0.20.20.4-0.3-0.6-0.6-0.6-0.70.3-0.30.0-0.60.60.20.0-0.5
Number of licking bursts1.83.04.9-1.7-2.0-1.8-1.8-1.31.9-2.21.8-1.61.11.2-1.8-1.7
Context. condit. distance diff. score4.65.59.6-1.9-2.1-3.1-2.1-3.12.0-1.61.8-2.82.62.8-2.1-1.9
Locomotion velocity, session 10.91.02.1-1.2-1.1-1.1-1.5-1.10.9-0.50.7-1.31.00.4-0.5-1.1
Locomotion distance, session 10.50.61.40.80.6-0.30.5-1.1-0.81.0-1.0-0.71.20.30.7-0.2
Locomotion velocity, session 20.70.81.6-0.7-1.0-1.1-1.0-1.10.7-0.80.7-1.31.10.7-0.6-1.0
Locomotion distance, session 20.60.93.00.3-0.1-1.1-0.0-1.7-0.10.4-0.3-1.31.51.5-0.1-0.5
Locomotion velocity, session 30.50.51.60.50.70.80.40.5-0.80.8-0.90.3-0.3-1.31.00.3
Locomotion distance, session 30.70.72.60.40.2-0.6-0.1-1.4-0.40.7-0.8-1.31.60.50.6-1.0
Stereotopy head waving bouts, day 31.11.22.7-1.5-1.4-0.6-1.20.21.6-1.41.6-0.1-0.60.2-1.4-0.7
Stereotopy head waving duration, day 30.70.81.6-1.2-1.00.1-1.00.81.2-0.91.30.5-1.1-0.6-0.8-0.4
Locomotion velocity, session 71.82.06.90.70.2-1.50.2-2.6-0.50.6-0.7-2.02.52.00.2-1.0
Locomotion distance, session 71.92.48.60.70.2-1.5-0.1-2.6-0.51.0-1.0-2.22.91.60.6-1.6
Stereotopy head waving bouts, day 70.40.42.0-0.7-0.70.2-0.90.40.5-0.30.4-0.2-0.1-1.40.2-0.8
Stereotopy head waving duration, day 70.30.31.9-0.5-0.40.4-0.50.70.4-0.20.20.2-0.5-1.40.2-0.3
Locomotion velocity, session 86.37.59.8-3.1-3.1-2.9-3.1-2.33.1-2.92.8-2.61.62.4-2.8-2.5
Locomotion distance, session 83.95.613.9-1.3-1.7-3.2-1.6-3.71.5-1.11.2-3.13.03.6-1.9-1.6
Degree of sensitization distance1.01.11.6-1.0-1.2-1.2-1.0-0.81.2-1.21.3-0.80.61.1-1.3-0.6
Degree of sensitization stereotypy0.20.31.5-0.3-0.40.0-0.7-0.00.1-0.0-0.0-0.50.4-1.20.5-0.8
Conditioned locomotion0.30.41.0-0.5-0.4-0.1-0.00.40.6-0.80.70.5-0.70.6-1.00.7
Cocaine response after cond. corrected0.40.53.00.2-0.1-0.90.4-1.10.2-0.40.2-0.60.81.7-0.8-0.0
Cocaine response after cond. not corrected0.81.02.0-1.0-1.1-1.0-0.7-0.41.2-1.41.3-0.50.11.1-1.4-0.3
Cocaine response before conditioning1.61.93.3-1.8-1.30.5-1.51.81.4-1.51.70.8-1.8-1.6-0.8-0.1
Saline control response4.45.912.71.72.13.11.93.6-1.91.8-1.53.0-2.7-3.22.11.9
Bone: connectivity density0.40.71.61.30.9-0.11.0-0.6-1.01.0-1.1-0.20.90.70.60.4
Bone: cortical apparent density1.92.64.21.81.81.82.11.4-1.71.6-1.51.6-1.3-1.31.41.5
Bone: cortical area0.10.10.3-0.4-0.6-0.2-0.3-0.00.5-0.40.6-0.2-0.20.0-0.4-0.1
Bone: cortical porosity0.70.73.4-1.0-0.80.1-1.4-0.10.6-0.50.4-0.60.1-1.80.3-1.1
Bone: cortical porosity1.11.23.4-1.5-1.3-0.4-1.8-0.41.2-1.11.0-0.90.2-1.3-0.3-1.3
Bone: cortical thickness1.22.03.21.81.51.51.70.8-1.61.7-1.51.0-0.7-1.51.61.0
Bone: cortical thickness2.83.34.82.21.92.02.11.4-2.02.1-1.81.5-1.1-1.81.91.6
Bone: cortical tissue density1.72.43.71.71.71.81.91.4-1.61.4-1.41.6-1.3-1.31.31.5
Condit. Reinf. active minus inactive responses0.30.31.0-0.2-0.3-0.4-0.7-0.8-0.00.3-0.3-1.01.0-0.50.6-0.7
Condit. Reinf. active-inactive response ratio0.40.42.10.50.40.80.30.4-0.60.4-0.60.3-0.3-1.51.00.3
Condit. Reinf. active responses0.40.41.20.40.3-0.3-0.1-0.9-0.61.0-0.8-0.91.10.10.8-0.4
Condit. Reinf. inactive responses1.11.43.51.41.1-0.10.9-1.0-1.31.9-1.6-0.71.40.81.3-0.3
Incentive salience index mean1.72.14.8-1.0-1.3-1.9-1.4-2.10.9-0.50.6-2.22.01.5-0.7-1.4
Condit. Reinf. lever presses3.54.912.3-1.4-1.8-2.9-1.6-3.01.6-1.11.2-2.72.53.5-1.9-1.7
Condit. Reinf. active minus inactive responses0.30.41.1-0.8-0.40.4-0.60.80.5-0.80.70.5-1.0-0.9-0.30.1
Condit. Reinf. active-inactive response ratio1.01.23.3-1.5-1.1-0.1-1.20.61.2-1.81.60.2-1.0-0.7-1.1-0.2
Condit. Reinf. active responses0.10.10.5-0.30.00.5-0.20.50.00.1-0.00.4-0.6-0.70.20.1
Condit. Reinf. inactive responses0.60.82.51.00.90.80.90.4-0.91.6-1.20.6-0.2-0.51.10.6
Condit. Reinf. lever presses0.10.10.4-0.20.10.1-0.4-0.3-0.20.4-0.4-0.20.3-0.60.5-0.1
Condit. Reinf. lever reinforcers received0.10.10.4-0.5-0.20.2-0.50.30.2-0.10.10.1-0.4-0.70.1-0.2
Conditioned reinforcement - actives0.30.41.90.60.70.60.50.5-0.60.5-1.40.9-0.30.20.70.2
Conditioned reinforcement - inactives0.20.30.70.40.60.70.30.4-0.40.5-0.80.7-0.6-0.40.60.4
Conditioned locomotion0.10.10.2-0.30.10.1-0.1-0.20.1-0.4-0.40.3-0.20.4-0.40.3
Patch foraging indifference point 0 sec1.93.56.11.51.72.41.62.5-1.41.8-1.32.4-2.1-1.81.71.6
Patch foraging indifference point AUC0.20.20.5-0.6-0.7-0.1-0.70.30.6-0.60.5-0.2-0.0-0.5-0.1-0.7
Delay disc. indifference point, 0s delay0.80.92.1-0.9-1.0-1.0-0.8-0.61.3-0.81.1-0.80.51.5-1.0-0.6
Delay disc. indifference point, 16s delay0.20.30.60.60.60.70.50.6-0.30.3-0.30.3-0.3-0.70.80.3
Delay disc. indifference point, 2s delay1.21.43.1-1.6-1.4-0.7-1.50.21.7-1.21.6-0.4-0.30.5-0.9-1.2
Delay disc. indifference point, 24s delay0.20.31.4-0.4-0.10.5-0.40.50.4-0.40.50.1-0.6-1.20.10.2
Delay disc. indifference point, 4s delay0.50.51.1-0.8-0.70.1-0.61.10.9-0.90.90.4-0.8-0.5-0.3-0.1
Delay disc. indifference point, 8s delay0.20.20.8-0.3-0.4-0.3-0.4-0.30.7-0.30.4-0.70.40.2-0.2-0.9
Indifference point function ln k0.61.11.6-1.1-1.3-1.2-1.3-1.21.2-0.70.9-1.20.90.7-0.9-1.2
Indifference point function log k0.61.11.6-1.1-1.3-1.2-1.3-1.21.2-0.70.9-1.20.90.7-0.9-1.2
Patch foraging total patch changes 0 sec2.03.76.41.61.82.51.72.5-1.51.9-1.42.4-2.1-1.91.81.6
Patch foraging total patch changes 12 sec1.72.14.41.21.31.91.32.1-1.11.3-1.11.8-1.5-1.61.31.1
Patch foraging total patch changes 18 sec3.45.28.12.82.62.52.82.1-2.42.5-2.32.1-1.4-1.52.41.7
Patch foraging total patch changes 24 sec2.03.46.52.32.21.72.11.0-2.22.6-2.21.2-0.3-1.32.21.2
Patch foraging total patch changes 6 sec2.43.66.11.61.82.31.72.5-1.72.1-1.62.2-1.7-1.81.81.7
Patch foraging time to switch 0 sec0.91.94.21.71.71.02.00.6-1.51.4-1.31.3-0.80.20.72.0
Patch foraging water rate 0 sec0.00.10.3-0.2-0.20.2-0.10.50.3-0.20.50.2-0.5-0.4-0.20.2
Patch foraging water rate 12 sec0.30.61.41.20.90.60.9-0.1-1.00.6-0.90.20.2-0.71.00.1
Patch foraging water rate 18 sec0.20.31.00.40.50.70.50.5-0.40.3-0.20.6-0.6-1.00.30.6
Patch foraging water rate 24 sec0.20.30.90.60.60.70.70.6-0.50.4-0.50.6-0.4-0.90.50.3
Patch foraging water rate 6 sec0.10.20.50.70.50.50.60.2-0.50.5-0.40.1-0.1-0.40.5-0.1
Seeking ratio, delayed vs. immediate footshock0.40.52.00.0-0.10.80.01.10.6-0.30.10.5-0.8-1.40.5-0.6
Distance traveled before self-admin0.20.20.7-0.2-0.2-0.30.2-0.00.0-0.60.7-0.0-0.30.8-0.80.5
Distance traveled after self-admin0.40.51.7-0.5-0.40.5-0.11.30.3-0.70.70.9-1.3-1.0-0.30.5
Extensor digitorum longus weight0.20.82.2-1.1-1.0-0.8-0.9-0.41.1-0.91.2-0.2-0.11.5-1.2-0.0
Bone: elastic displacement0.50.61.50.80.80.80.50.0-0.91.1-0.90.2-0.1-1.11.2-0.0
Bone: elastic work0.10.10.30.20.30.50.20.2-0.30.4-0.10.3-0.5-0.40.40.2
Bone: endosteal estimation2.75.912.7-3.4-2.7-1.1-2.50.93.1-3.63.50.3-1.71.1-3.2-0.2
Bone: endosteal perimeter2.85.910.3-3.1-3.0-2.1-2.6-0.73.1-3.23.2-1.1-0.02.2-3.1-1.1
Epididymis fat weight8.328.542.66.46.35.66.54.2-5.95.7-5.25.2-3.5-3.45.05.4
Delta time in closed arm before/after self-admin0.20.20.9-0.20.00.10.20.50.2-0.40.10.8-0.80.2-0.41.0
Delta time in open arm before/after self-admin0.50.50.80.70.80.70.50.7-0.90.9-0.60.6-0.4-0.70.70.2
Diff in mean of infusions in LGA sessions1.01.34.20.3-0.4-1.4-0.1-1.70.4-0.1-0.4-1.52.01.90.0-1.1
Delay discount exponential model param0.30.30.90.60.70.10.7-0.3-0.90.6-0.80.30.20.20.20.6
Extinction: sum of active levers before priming1.01.12.2-1.1-1.2-1.2-1.1-0.71.3-1.40.4-0.90.81.5-0.9-0.9
Active lever presses in extinction session 60.60.61.80.70.80.60.50.1-1.01.3-1.00.3-0.1-0.60.90.9
Bone: final force1.11.73.71.01.01.51.41.8-0.80.7-0.31.8-1.8-1.00.51.9
Bone: final moment1.01.53.20.91.01.41.31.7-0.80.7-0.31.7-1.8-1.00.51.8
Food consumed during 24 hour testing period0.40.51.9-0.6-0.6-0.5-0.20.10.8-0.71.00.1-0.51.4-1.20.3
Glucose6.39.915.0-3.9-3.6-3.3-3.7-2.53.6-3.23.5-2.71.42.7-3.5-2.3
Heart weight0.81.23.3-1.3-0.70.6-0.91.81.1-0.81.10.9-1.8-1.2-0.7-0.0
Delay discount hyperbolic model param0.30.41.10.70.80.10.8-0.4-1.00.6-0.90.30.20.20.20.7
Intermittent access intake day 1-15 change0.10.21.00.4-0.00.20.10.6-0.51.0-0.60.30.10.00.5-0.2
Intermittent access intake escalation0.51.03.11.10.71.00.61.1-1.21.8-1.20.8-0.2-0.71.40.0
Intermittent access intake escalation 20.10.10.4-0.1-0.4-0.2-0.50.0-0.20.6-0.1-0.10.40.30.2-0.5
Intermitt. access day 1 inactive lever presses0.62.34.7-1.8-1.7-1.6-1.4-0.92.1-2.21.7-0.70.31.8-1.8-0.6
Intermitt. access day 15 inactive lever presses0.10.20.8-0.4-0.10.2-0.10.80.0-0.20.30.5-0.8-0.2-0.20.9
Intermitt. access escalation Index1.11.53.4-0.2-0.9-1.7-0.6-1.70.50.00.2-1.81.91.8-0.7-1.5
Intermittent access day 1 total infusions0.30.41.40.40.5-0.2-0.0-0.8-1.00.6-1.2-0.40.90.40.7-0.1
Intermittent access day 15 total infusions0.71.02.81.10.90.70.60.6-1.51.5-1.70.50.3-0.41.5-0.0
Intermittent access terminal intake (last 3 days)0.50.61.50.50.70.80.20.7-1.21.0-1.20.7-0.2-0.71.10.2
Intermittent access total infusions0.40.51.70.60.90.60.30.3-1.00.8-1.30.40.1-0.41.00.0
Intermittent access day 1 locomotion0.40.61.50.81.00.50.80.2-1.20.7-1.20.5-0.00.20.51.0
Intermittent access day 15 total locomotion0.30.51.40.40.50.80.61.2-0.80.3-0.51.2-0.90.10.30.8
Intermittent access total locomotion0.70.81.60.81.01.00.80.9-1.10.4-1.21.3-0.6-0.30.71.0
Intermittent access standard deviation1.22.55.51.01.31.91.32.2-1.31.0-0.92.3-2.0-1.30.91.9
Left kidney weight1.36.016.70.81.42.91.83.8-0.90.6-0.33.7-4.1-2.40.43.6
Right kidney weight1.15.215.50.81.32.61.93.5-0.80.5-0.23.5-3.9-1.50.13.4
Cocaine induced anxiety0.30.40.7-0.6-0.8-0.8-0.4-0.50.7-0.40.9-0.60.40.8-0.80.0
Post-drug Anxiety0.20.20.7-0.4-0.4-0.2-0.20.50.6-0.60.80.3-0.30.5-0.6-0.1
Baseline Anxiety0.10.10.3-0.10.10.40.10.5-0.0-0.40.10.6-0.50.20.0-0.4
Tail length1.14.29.0-3.0-2.30.0-2.31.72.7-2.32.90.8-2.4-0.4-2.0-0.3
Length with tail1.14.810.2-2.9-2.20.0-1.81.92.7-2.53.21.4-3.00.3-2.60.6
Length without tail0.92.88.2-1.3-0.80.30.01.71.3-1.62.11.7-2.90.8-2.42.4
Times rat made contact with spout1.72.05.41.71.31.01.00.1-1.62.2-2.0-0.10.7-1.42.3-0.3
Lifetime Intake0.30.41.40.50.80.60.30.4-0.90.7-1.20.5-0.1-0.30.80.0
Liver weight, left1.52.55.5-2.2-1.9-1.1-1.5-0.11.9-2.02.3-0.2-0.81.0-2.40.8
Liver weight, right2.13.77.8-2.6-2.4-1.6-2.2-0.22.4-2.22.8-0.6-0.51.7-2.60.0
Locomotor activity0.61.02.7-1.3-1.10.0-1.10.71.3-1.71.30.3-0.9-0.5-0.8-0.5
Locomotor testing distance0.40.61.7-1.1-0.8-0.2-0.80.51.0-1.31.10.2-0.70.4-0.9-0.2
Locomotor testing rearing0.30.61.3-0.6-0.40.1-0.20.90.6-0.91.00.9-1.10.6-0.90.6
Locomotion in novel chamber0.10.10.30.30.20.20.30.5-0.00.30.30.5-0.2-0.00.1-0.0
Locomotion in novel chamber post-restriction0.50.82.50.50.81.21.01.4-0.60.30.21.2-1.6-0.60.40.6
Fecal boli incidents, locomotor time 10.10.20.70.50.80.30.60.2-0.20.5-0.30.5-0.30.50.30.2
Change in fecal boli incidents, locomotor task1.81.73.3-1.7-1.7-1.1-1.3-0.41.5-1.51.8-0.6-0.01.2-1.8-0.9
Time >=10cm from walls, locomotor time 10.91.02.6-0.9-0.8-0.3-0.10.31.0-1.31.60.6-1.31.2-1.20.8
Bouts of movement, locomotor time 10.40.41.60.1-0.4-0.7-0.2-1.3-0.0-0.3-0.0-1.21.10.2-0.0-0.7
Total resting periods, locomotor time 10.40.41.5-0.2-0.5-0.7-0.4-1.20.1-0.40.1-1.20.90.3-0.2-0.6
Rest time, locomotor task time 10.20.30.7-0.7-0.6-0.4-0.8-0.40.9-0.20.5-0.2-0.10.4-0.4-0.8
Distance moved, locomotor task time 10.10.20.40.20.20.50.40.6-0.4-0.0-0.20.4-0.5-0.50.20.6
Vertical activity count, locomotor time 10.30.81.51.00.80.91.21.2-0.80.4-0.71.0-0.8-0.80.60.9
Time >=10cm from walls, locomotor time 20.71.12.9-1.4-0.9-0.3-0.60.51.4-1.61.70.3-1.20.7-1.20.0
Bouts of movement, locomotor time 20.10.21.0-0.3-0.6-0.1-0.60.00.4-0.00.8-0.20.1-1.0-0.0-0.1
Total resting periods, locomotor time 20.40.61.8-0.8-1.1-0.6-1.2-0.40.9-0.31.3-0.60.3-0.7-0.4-0.7
Rest time, locomotor task time 21.62.04.1-1.2-1.5-1.7-1.2-1.61.1-1.31.6-1.10.72.0-1.8-0.9
Distance moved, locomotor task time 21.21.52.40.81.31.41.31.5-1.00.9-1.01.2-1.1-1.31.01.5
Vertical activity count, locomotor time 20.60.81.90.50.91.01.01.4-0.40.2-0.71.1-1.1-0.90.61.0
Light reinforcement 10.20.41.30.80.50.41.10.9-0.20.8-0.40.7-0.50.3-0.00.8
Light reinforcement 20.10.20.9-0.1-0.1-0.20.30.30.2-0.10.40.3-0.30.9-0.70.9
Bone: marrow area2.65.611.9-3.3-2.6-0.9-2.31.13.1-3.43.40.5-1.91.0-3.1-0.0
Bone: maximum diameter2.34.36.6-2.4-2.5-2.1-2.3-1.22.4-2.62.4-1.70.81.7-2.3-1.4
Bone: maximum force0.50.92.60.50.61.00.91.3-0.50.4-0.11.4-1.5-0.50.11.6
Bone: maximum moment0.40.72.10.30.50.90.71.2-0.30.30.01.2-1.4-0.50.11.4
Mean time between licks in bursts1.74.15.6-2.2-2.3-2.2-2.4-1.62.3-2.02.3-1.81.21.7-2.1-1.9
Mean num. licks in bursts3.14.99.42.42.52.32.11.4-2.63.1-2.71.5-0.8-1.92.81.4
Cd content in liver0.91.12.21.31.40.71.50.1-1.31.3-1.10.6-0.30.40.71.3
Co content in liver1.41.63.11.11.31.51.51.3-1.20.8-0.81.6-1.5-0.90.71.8
Cu content in liver1.51.84.21.61.30.81.1-0.6-1.71.9-2.0-0.30.9-1.02.1-0.2
Fe content in liver1.41.82.41.41.51.51.51.4-1.41.1-1.01.5-1.2-1.01.11.6
K content in liver0.40.41.50.1-0.2-0.7-0.2-1.20.00.2-0.1-0.81.10.7-0.1-0.3
Mg content in liver3.33.45.3-1.7-1.9-2.3-1.8-2.21.8-1.51.5-2.01.82.0-1.8-1.3
Mn content in liver4.65.17.9-2.3-2.4-2.6-2.2-2.22.5-2.32.3-2.01.22.8-2.6-1.4
Na content in liver0.20.30.70.60.20.20.2-0.0-0.40.6-0.7-0.30.6-0.60.8-0.6
Rb content in liver0.20.21.40.20.2-0.50.2-0.3-0.00.40.0-0.10.41.2-0.40.3
Se content in liver4.75.69.3-2.7-2.9-2.6-3.0-1.92.6-2.22.2-2.61.81.4-1.8-2.4
Sr content in liver0.30.20.5-0.4-0.20.0-0.20.40.4-0.70.70.5-0.70.1-0.70.6
Zn content in liver0.30.30.6-0.7-0.5-0.6-0.5-0.70.6-0.30.6-0.40.20.8-0.7-0.1
Bone: minimum diameter2.03.66.6-2.4-2.3-1.6-1.9-0.82.5-2.22.6-0.9-0.21.9-2.5-0.8
Time in familiar zone, hab. session 12.92.87.22.11.91.21.5-0.1-2.12.7-2.40.20.7-1.02.5-0.1
Time in novel zone, hab. session 11.81.84.4-1.8-1.5-0.6-1.20.71.7-2.11.90.2-1.00.4-1.90.3
Total zone transitions, hab. session 10.20.30.9-0.1-0.3-0.7-0.3-0.90.20.4-0.0-0.80.90.9-0.1-0.6
Total locomotion distance, hab. session 10.20.31.30.1-0.1-0.7-0.1-0.90.00.7-0.1-0.70.91.1-0.1-0.5
Locomotion velocity, hab. session 10.10.20.6-0.0-0.2-0.6-0.2-0.70.10.60.0-0.50.70.8-0.1-0.4
Time in familiar zone, hab. session 20.91.01.91.41.01.01.20.5-1.11.2-1.10.7-0.2-0.91.30.6
Time in novel zone, hab. session 20.20.20.5-0.7-0.3-0.0-0.50.50.4-0.50.40.1-0.4-0.3-0.40.0
Total zone transitions, hab. session 20.10.20.90.50.1-0.30.5-0.5-0.10.3-0.3-0.20.41.0-0.1-0.1
Total locomotion distance, hab. session 20.50.62.80.70.2-0.80.5-1.1-0.20.7-0.4-0.61.21.7-0.1-0.3
Locomotion velocity, hab. session 20.71.04.10.4-0.1-1.20.2-1.50.10.5-0.2-1.11.62.0-0.3-0.7
Novel to familiar place preference ratio0.10.10.2-0.1-0.2-0.2-0.3-0.30.10.00.1-0.30.4-0.00.1-0.4
Novelty place preference0.10.10.3-0.3-0.4-0.2-0.5-0.10.2-0.20.3-0.30.3-0.2-0.0-0.5
Time in novel zone, NPP test0.10.10.3-0.4-0.4-0.1-0.60.10.3-0.30.4-0.20.1-0.4-0.0-0.5
Total zone transitions, NPP test0.50.72.20.1-0.0-1.0-0.1-1.5-0.00.5-0.4-1.11.51.5-0.1-0.6
Total locomotion distance, NPP test0.50.72.90.70.5-0.80.6-1.2-0.50.9-0.6-0.61.21.7-0.00.1
Locomotion velocity, NPP test0.81.14.50.70.5-1.00.6-1.6-0.51.0-0.7-0.91.62.1-0.0-0.2
Intraocular pressure0.81.11.91.41.40.91.40.4-1.31.3-1.40.50.0-0.41.20.7
Delta distance traveled before/after self-admin0.70.83.3-0.5-0.20.9-0.51.50.5-0.20.11.0-1.3-1.80.4-0.0
Delta ambulatory time before/after self-admin0.50.62.5-0.7-0.50.5-0.71.10.8-0.40.50.7-1.0-1.60.1-0.2
Parametrial fat weight1.74.07.92.22.22.02.72.1-2.01.2-1.42.2-1.9-1.01.02.8
Pavlov. Cond. lever latency5.67.110.42.62.63.13.03.1-2.32.2-1.93.2-2.7-2.51.92.9
Pavlov. Cond. magazine entry latency3.14.06.7-2.0-2.2-2.1-2.5-2.21.9-1.51.5-2.52.00.9-1.1-2.6
Pavlov. Cond. change in total contacts2.22.33.8-1.7-1.7-1.5-2.0-1.41.5-1.61.3-1.81.20.7-0.9-1.9
Pavlov. Cond. index score5.56.910.6-2.5-2.8-3.0-3.0-3.12.4-2.12.0-3.32.62.1-1.8-3.0
Pavlov. Cond. latency score5.97.511.0-2.6-2.9-3.1-3.1-3.12.5-2.32.1-3.32.72.3-1.9-3.1
Pavlov. Cond. lever contacts5.56.69.4-2.5-2.5-3.1-2.7-3.02.3-2.22.0-3.02.42.8-2.2-2.4
Pavlov. Cond. magazine entry number2.02.64.21.61.81.72.01.9-1.51.2-1.22.1-1.6-0.80.92.0
Pavlov. Cond. intertrial magazine entries2.53.05.12.02.21.62.21.2-2.12.0-2.11.3-0.7-0.81.71.5
Pavlov. Cond. lever-magazine prob. diff.5.36.510.4-2.4-2.6-2.9-2.9-3.12.3-1.91.9-3.22.62.0-1.7-2.9
Pavlov. Cond. response bias3.84.77.5-2.1-2.3-2.5-2.5-2.62.0-1.61.6-2.72.21.7-1.5-2.4
Pavlov. Cond. lever latency0.60.82.0-0.7-0.9-0.9-0.5-0.21.1-0.91.1-0.40.01.4-1.3-0.6
Pavlov. Cond. magazine entry latency0.20.20.4-0.5-0.5-0.5-0.7-0.50.4-0.60.6-0.50.40.3-0.4-0.4
Pavlov. Cond. change in total contacts0.20.32.10.10.40.7-0.00.4-0.4-0.0-0.40.4-0.3-1.50.70.2
Pavlov. Cond. index score0.00.10.4-0.10.00.2-0.3-0.1-0.20.0-0.1-0.10.1-0.60.4-0.1
Pavlov. Cond. latency score0.10.10.60.00.20.4-0.10.1-0.30.1-0.20.2-0.1-0.80.50.1
Pavlov. Cond. lever contacts0.50.61.80.70.80.80.50.2-1.00.7-1.00.4-0.1-1.31.10.7
Pavlov. Cond. magazine entry number0.00.00.1-0.1-0.10.10.00.10.10.3-0.20.0-0.1-0.20.0-0.0
Pavlov. Cond. intertrial magazine entries0.91.32.0-1.2-1.4-1.4-1.4-1.11.2-0.80.8-1.41.10.8-0.8-1.3
Pavlov. Cond. lever-magazine prob. diff.0.00.10.3-0.00.10.2-0.2-0.1-0.20.1-0.2-0.00.1-0.60.4-0.0
Pavlov. Cond. response bias0.10.10.30.10.20.1-0.2-0.4-0.40.1-0.3-0.30.5-0.60.5-0.0
Time in closed arm before self-admin0.20.20.9-0.8-0.6-0.3-0.60.20.5-0.40.9-0.1-0.10.1-0.4-0.2
Time in closed arm after self-admin0.00.10.2-0.1-0.00.0-0.00.30.10.20.20.5-0.30.30.20.1
Time in open arm before self-admin0.50.61.5-0.7-0.7-0.6-1.0-1.00.7-0.50.2-1.10.90.1-0.1-1.2
Time in open arm after self-admin0.10.10.7-0.20.00.2-0.4-0.0-0.1-0.1-0.3-0.1-0.1-0.80.0-0.2
Bone: periosteal estimation1.32.75.9-2.2-1.9-0.5-1.60.92.2-2.42.40.4-1.50.5-2.1-0.0
Bone: periosteal perimeter1.42.44.3-2.0-2.0-1.2-1.8-0.52.1-2.12.1-0.8-0.11.0-1.8-0.9
Bone: post-yield work1.11.73.7-1.6-1.4-1.2-1.2-0.31.6-1.61.6-0.3-0.21.7-1.9-0.0
Progressive ratio test 1 active lever presses0.10.10.4-0.00.20.1-0.1-0.2-0.40.2-0.60.2-0.00.30.20.6
Progressive ratio test 1 breakpoint0.10.10.3-0.10.20.1-0.1-0.2-0.40.1-0.50.2-0.10.30.20.6
Progressive ratio test 1 inactive lever presses0.60.91.81.21.20.71.20.4-1.10.4-1.31.0-0.30.31.01.2
Progressive ratio test 2 active lever presses0.40.41.90.80.50.10.3-0.2-0.90.8-1.40.20.70.50.8-0.0
Progressive ratio test 2 breakpoint0.50.52.00.90.60.20.4-0.1-1.10.9-1.40.20.70.41.0-0.0
Progressive ratio test 2 inactive lever presses0.20.41.6-0.7-0.5-0.7-0.8-0.30.5-0.2-0.3-0.30.41.3-0.5-0.6
Incentive Sensitization - Responses0.20.31.00.4-0.1-0.4-0.2-0.4-0.50.5-0.7-0.31.00.80.6-1.0
Incentive Sensitization - Breakpoint0.30.41.00.70.1-0.30.0-0.3-0.70.7-0.9-0.21.00.70.7-0.8
Sum of active levers in priming session hrs 5-60.20.20.6-0.7-0.5-0.4-0.8-0.40.5-0.2-0.0-0.30.10.2-0.4-0.6
Progressive ratio2.33.67.71.21.32.41.72.7-1.21.1-0.42.6-2.8-2.30.62.0
Food seeking constrained by brief footshock0.30.30.70.50.60.60.30.9-0.50.3-0.20.7-0.3-0.90.60.6
Seeking ratio, punishment vs. effort1.72.54.8-1.2-1.3-1.9-1.7-2.11.3-1.30.6-2.02.21.6-0.4-1.7
Retroperitoneal fat weight0.20.81.71.21.10.71.30.6-1.01.0-0.70.9-0.40.30.61.2
Reaction time number correct1.53.04.51.51.82.11.81.9-1.61.1-1.31.9-1.7-2.11.31.9
Reaction time mean minus median1.02.44.2-1.2-1.5-1.9-1.6-2.01.1-0.80.9-1.91.82.0-1.1-1.5
Reaction time mean minus median AUC0.92.25.2-1.1-1.2-1.9-1.5-2.30.8-0.90.7-2.01.91.8-1.0-1.2
Reaction time num false alarms0.71.01.7-0.9-1.3-1.0-1.1-0.61.2-1.01.2-1.00.70.5-0.9-1.3
Reaction time num false alarms AUC0.91.42.6-1.2-1.6-1.0-1.4-0.51.5-1.41.4-1.00.60.2-1.0-1.5
Reaction time trials correct on left1.53.04.51.51.82.11.81.9-1.61.1-1.31.9-1.7-2.11.31.9
Reaction time trials on left1.52.84.41.41.72.11.71.9-1.51.1-1.21.9-1.7-2.11.31.9
Reaction time mean2.33.76.7-1.6-1.8-2.5-1.6-2.41.5-1.91.5-2.11.82.6-2.0-1.1
Reaction time mean AUC2.13.36.2-1.5-1.6-2.4-1.6-2.31.4-1.81.4-2.01.72.5-1.8-1.1
Median of all reaction times1.82.64.9-1.4-1.4-2.1-1.3-1.91.3-1.91.4-1.61.32.2-1.8-0.7
Reaction time omissions1.62.34.6-1.3-1.4-1.9-1.3-1.61.3-1.61.3-1.51.32.1-1.6-1.2
Reaction time false alarm rate3.04.26.5-2.1-2.5-2.2-2.4-1.52.3-2.02.0-2.11.51.3-1.7-2.5
Reaction time premature initiation rate0.20.30.9-0.30.30.40.20.8-0.1-0.10.10.8-1.0-0.0-0.40.9
Reaction time premature initiations1.01.84.00.51.21.61.21.9-0.90.5-0.61.9-2.0-1.20.42.0
Std. dev. reaction times2.34.25.9-2.1-2.2-2.4-2.3-2.31.9-1.81.7-2.31.82.1-1.8-1.9
Reaction time trials completed1.52.84.41.41.72.11.71.9-1.51.1-1.21.9-1.7-2.11.31.9
Reaction time trials AUC1.42.74.11.41.72.01.81.8-1.51.0-1.21.8-1.7-2.01.21.9
Run reversals in cocaine runway, females0.80.81.51.01.21.01.00.4-1.21.2-0.81.0-0.6-0.30.60.8
Run reversals in cocaine runway, males0.70.71.5-0.9-0.8-1.0-0.9-0.70.8-0.70.7-0.70.61.2-0.9-1.0
Latency to leave start box in cocaine runway1.31.52.5-1.0-1.2-1.6-1.0-1.11.4-1.01.3-1.51.11.6-1.0-1.1
Latency to leave start box in cocaine runway, F0.81.02.6-0.7-0.8-1.3-0.7-1.00.9-0.91.0-1.11.01.6-0.7-0.7
Latency to leave start box in cocaine runway, M0.40.40.8-0.6-0.7-0.7-0.5-0.30.9-0.40.7-0.80.20.3-0.6-0.7
Std. dev. time between licks in bursts4.35.89.5-2.9-2.8-2.3-2.8-1.22.9-3.13.0-1.60.71.7-2.9-1.6
Total sessions with >9 infusions0.20.20.80.20.40.5-0.00.1-0.60.5-0.90.3-0.2-0.40.6-0.1
Short access day 1 total inactive lever presses0.71.01.9-1.3-0.8-0.8-1.2-0.91.4-1.21.0-0.60.10.9-1.0-1.0
Short access day 10 total inactive lever presses0.20.41.50.2-0.5-1.0-0.1-0.80.4-0.20.3-0.50.91.2-0.1-0.5
Short access day 1 total infusions0.10.10.3-0.5-0.1-0.2-0.6-0.2-0.20.4-0.3-0.20.20.30.2-0.1
Short access day 10 total infusions0.30.31.00.80.90.40.50.0-0.90.6-1.00.20.2-0.30.70.3
Short access total infusions0.10.10.60.20.50.30.00.0-0.50.6-0.80.10.1-0.00.60.0
Short access day 1 locomotion0.50.61.7-0.1-0.4-1.0-0.4-1.2-0.0-0.3-0.4-0.81.31.3-0.3-0.6
Short access day 10 total locomotion0.71.23.3-1.5-1.3-0.2-1.00.80.9-1.81.50.6-1.20.4-1.40.4
Short access total locomotion0.30.41.4-0.8-0.6-0.4-0.5-0.20.5-1.20.60.1-0.30.9-1.00.2
One hour access (0.3 mA shock)0.80.93.50.5-0.2-1.0-0.1-0.9-0.30.5-0.9-0.91.91.50.3-1.5
Compulsive drug intake3.54.211.2-1.3-2.1-2.6-1.3-1.91.6-1.21.8-2.12.03.3-2.0-2.2
One hour access (shock baseline)1.21.94.51.61.61.31.10.8-1.81.4-2.10.9-0.1-1.21.90.5
Social response proportion0.70.81.8-1.3-0.9-0.3-0.90.11.1-1.31.20.2-0.90.6-1.10.2
Social responses0.50.61.3-1.1-0.9-0.1-0.90.41.1-1.10.90.1-0.80.1-0.8-0.3
Social time3.34.57.0-1.8-2.3-2.4-1.9-1.72.2-2.62.1-1.81.42.6-2.3-1.9
Soleus weight3.711.019.1-4.1-3.9-3.1-3.4-1.64.1-4.34.2-1.70.33.1-4.4-1.4
Bone: stiffness0.60.91.61.10.91.01.31.1-0.91.0-0.61.1-0.9-0.40.61.3
Tibialis anterior weight0.41.42.51.41.31.21.40.7-1.31.6-1.40.9-0.6-0.71.40.9
Time to tail flick, vehicle, before self-admin0.50.51.40.8-0.1-0.60.6-0.9-0.10.0-0.5-0.71.21.10.2-1.0
Time to tail flick, vehicle, after self-admin0.60.81.5-0.9-1.0-1.0-0.9-0.90.8-0.50.4-1.11.01.1-0.7-1.2
Time to tail flick, test, before self-admin0.20.30.90.60.20.40.30.3-0.70.8-0.4-0.00.4-0.40.9-0.3
Time to tail flick, test, after self-admin0.60.72.20.50.1-0.4-0.2-0.8-0.60.9-0.8-0.91.50.31.0-1.1
Delta time to tail flick, vehicle, before/after SA0.10.10.7-0.10.3-0.0-0.3-0.3-0.30.8-0.4-0.30.4-0.20.5-0.1
Delta time to tail flick, test, before/after SA0.30.30.90.80.6-0.10.5-0.7-0.70.6-0.9-0.20.50.30.40.2
Tibia length1.23.37.6-2.3-1.8-0.5-1.51.62.3-2.22.80.8-2.00.9-2.50.6
Ambulatory time before self-admin0.00.10.4-0.0-0.1-0.20.1-0.1-0.30.00.3-0.20.10.6-0.10.2
Ambulatory time after self-admin0.30.41.3-0.6-0.40.4-0.41.20.3-0.20.60.7-1.1-0.8-0.00.2
Bone: tissue strength0.20.21.10.20.50.40.50.5-0.50.3-0.30.6-0.60.10.11.0
Total heroin consumption0.10.10.3-0.5-0.5-0.4-0.5-0.30.1-0.10.4-0.30.20.1-0.20.1
Bone: trabecular number1.32.14.62.21.70.31.6-0.6-1.92.1-2.0-0.31.4-0.01.70.2
Bone: trabecular spacing1.41.84.2-1.9-1.4-0.0-1.20.81.6-2.11.90.5-1.6-0.2-1.60.1
Bone: trabecular thickness1.21.43.31.81.50.41.5-0.1-1.71.6-1.60.10.8-0.11.30.8
Bone: trabecular tissue density0.20.31.0-0.5-0.50.3-0.70.80.4-0.30.50.2-0.3-1.00.1-0.5
Water consumed over 24 hours0.40.50.9-0.8-0.9-0.8-0.8-0.50.8-0.70.8-0.70.30.7-0.8-0.4
Number of responses in last shaping day2.32.56.2-2.5-2.0-1.1-2.2-0.11.9-2.01.6-0.8-0.20.6-1.7-1.2