Hub : Genes

Vps4b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Vps4b 0.22 0.12 6.5e-03 0.01 0.02 -0.01 0.03 1.6e-01 1.1e-01 9.1e-01 6.1e-02
2 Adipose mRNA stability Vps4b 0.23 0.1 1.1e-16 0.05 0.07 0.06 0.06 1.5e-06 3.7e-08 5.8e-07 2.1e-07
3 IC mRNA stability Vps4b 0.18 0.09 2.6e-04 0.04 0.03 0.03 0.02 1.3e-02 3.1e-02 2.7e-02 3.3e-02
4 IC gene expression Vps4b 0.59 0.12 0.0e+00 0.33 0.33 0.34 0.35 2.6e-14 1.8e-14 1.0e-14 1.6e-15
5 Adipose gene expression Vps4b 0.16 0.08 8.0e-10 0.05 0.04 0.03 0.04 4.1e-06 2.2e-05 1.2e-04 8.8e-06
6 BLA gene expression Vps4b 0.58 0.12 0.0e+00 0.27 0.25 0.28 0.28 7.7e-15 1.5e-13 1.8e-15 3.3e-15
7 Liver gene expression Vps4b 0.1 0.05 9.6e-08 0.04 0.04 0.04 0.04 1.5e-05 8.0e-06 1.1e-05 3.7e-05
8 Liver mRNA stability Vps4b 0.09 0.05 4.0e-07 0.02 0.03 0.03 0.03 1.1e-03 1.5e-04 2.2e-04 5.0e-04
9 LHb mRNA stability Vps4b 0.35 0.15 1.3e-04 0.11 0.11 0.08 0.09 1.7e-03 1.3e-03 4.9e-03 4.0e-03
10 pVTA gene expression Vps4b 0.74 0 0.0e+00 0.28 0.33 0.33 0.33 2.4e-22 4.5e-27 5.9e-27 3.0e-27
11 PL gene expression Vps4b 0.53 0.13 0.0e+00 0.29 0.33 0.34 0.33 9.3e-32 1.8e-37 1.2e-37 4.6e-37
12 NAcc gene expression Vps4b 0.39 0.09 0.0e+00 0.23 0.27 0.28 0.28 7.9e-35 2.4e-41 7.4e-43 6.9e-43
13 Brain mRNA stability Vps4b 0.24 0.08 1.1e-16 0.11 0.12 0.11 0.11 1.1e-10 3.5e-11 2.5e-10 2.1e-10
14 Brain gene expression Vps4b 0.66 0.1 0.0e+00 0.37 0.44 0.43 0.44 9.3e-36 1.4e-44 2.0e-43 3.4e-44
15 LHb gene expression Vps4b 0.6 0.14 2.2e-10 0.25 0.35 0.28 0.34 1.2e-06 3.0e-09 1.8e-07 5.1e-09
16 pVTA mRNA stability Vps4b 0.08 0.05 8.1e-03 0 0 -0 0 1.7e-01 1.6e-01 5.3e-01 1.7e-01
17 NAcc mRNA stability Vps4b 0.04 0.03 6.3e-03 -0 -0 -0 0 7.8e-01 9.4e-01 7.1e-01 6.5e-02
18 PL mRNA stability Vps4b 0.15 0.07 5.5e-08 0.03 0.04 0.03 0.03 3.6e-04 9.2e-05 1.7e-04 5.6e-04
19 OFC gene expression Vps4b 0.66 0.12 3.9e-13 0.31 0.31 0.26 0.27 3.6e-08 5.1e-08 5.7e-07 5.0e-07
20 IL gene expression Vps4b 0.72 0.16 7.2e-10 0.2 0.2 0.24 0.19 1.2e-05 1.1e-05 1.8e-06 2.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.20.41.6-0.80.00.21.21.00.70.9-0.30.10.80.60.70.40.90.70.4-0.50.1-0.30.2
Area under the delay curve0.91.05.22.31.10.7-1.6-1.9-0.3-1.51.20.6-0.8-0.5-1.00.0-0.6-0.70.20.20.60.1-0.1
BMI with tail1.13.87.60.9-0.6-1.6-2.3-2.3-2.3-2.8-1.1-1.6-2.3-2.4-2.4-1.9-2.1-2.0-1.9-2.1-1.6-1.8-1.4
BMI without tail0.41.23.20.4-0.1-0.8-1.2-1.1-0.7-1.6-0.5-0.9-1.3-1.2-1.1-1.0-0.9-1.4-0.8-1.8-0.8-1.8-1.2
Body weight0.94.011.52.10.6-0.9-3.1-3.4-1.7-3.2-0.1-0.7-2.3-2.2-2.9-1.3-1.8-1.8-1.4-2.0-0.8-2.0-1.2
Weight adjusted by age1.82.74.4-1.1-1.6-1.7-1.0-0.8-1.7-1.4-1.4-1.5-1.9-1.8-2.1-1.7-1.9-1.2-2.1-1.9-1.7-2.0-1.8
Bone surface0.40.82.1-1.4-1.1-0.90.90.9-0.50.2-1.4-1.0-0.2-0.3-0.1-0.7-0.2-0.2-0.9-1.4-1.2-1.3-0.7
Bone volume0.10.21.0-0.6-0.20.01.00.90.40.6-0.4-0.10.50.40.50.10.50.30.1-0.7-0.1-0.40.1
Breakpoint value in progressive ratio session0.20.20.80.80.3-0.1-0.9-0.7-0.1-0.70.1-0.1-0.4-0.4-0.4-0.2-0.3-0.60.0-0.4-0.0-0.5-0.5
Number of licking bursts0.40.72.11.41.30.9-0.3-0.40.5-0.21.21.10.30.50.20.90.50.70.60.41.00.91.4
Context. condit. distance diff. score0.00.00.20.2-0.10.20.0-0.2-0.2-0.10.00.1-0.1-0.1-0.40.0-0.10.2-0.3-0.00.1-0.3-0.4
Locomotion velocity, session 11.01.01.6-0.2-1.0-1.0-1.0-0.8-1.2-1.0-0.8-1.0-1.2-1.1-1.3-1.1-1.2-1.0-1.2-0.7-0.9-1.1-1.1
Locomotion distance, session 10.40.51.41.21.00.6-0.9-1.00.3-0.41.10.9-0.10.1-0.40.60.10.30.40.70.90.60.8
Locomotion velocity, session 20.60.73.21.70.80.3-1.8-1.6-0.0-1.11.00.4-0.7-0.5-0.9-0.0-0.5-0.70.30.20.50.2-0.1
Locomotion distance, session 20.81.12.91.41.71.0-0.6-0.70.8-0.21.61.40.30.50.11.00.40.61.01.41.11.41.6
Locomotion velocity, session 30.30.30.70.50.50.70.30.30.70.50.40.40.70.80.80.60.90.30.80.10.70.10.2
Locomotion distance, session 30.10.10.70.3-0.3-0.3-0.00.2-0.1-0.0-0.6-0.5-0.0-0.00.1-0.30.2-0.3-0.1-0.8-0.3-0.8-0.5
Stereotopy head waving bouts, day 30.40.51.60.31.00.70.20.20.50.21.00.90.40.60.40.80.50.70.71.20.71.11.0
Stereotopy head waving duration, day 30.50.62.2-0.20.60.80.60.70.60.70.80.80.60.80.70.80.60.80.61.50.61.10.9
Locomotion velocity, session 70.60.63.3-1.8-1.3-0.61.11.4-0.11.0-1.0-0.60.30.30.6-0.20.20.3-0.4-0.4-0.5-0.5-0.5
Locomotion distance, session 70.00.00.1-0.2-0.10.10.20.40.10.3-0.00.10.20.30.30.20.20.30.00.10.10.20.2
Stereotopy head waving bouts, day 70.80.92.61.61.31.0-0.2-0.40.80.11.31.10.60.60.50.90.60.51.11.21.21.10.9
Stereotopy head waving duration, day 70.10.10.80.90.30.1-0.5-0.7-0.0-0.30.40.1-0.2-0.1-0.10.0-0.1-0.40.30.20.30.2-0.1
Locomotion velocity, session 81.92.33.80.21.01.61.21.21.51.71.31.71.71.81.51.71.61.91.31.71.71.61.6
Locomotion distance, session 80.60.91.60.91.11.20.30.10.90.51.21.30.81.00.51.10.91.10.91.11.21.01.1
Degree of sensitization distance0.20.21.1-0.10.30.60.20.20.20.30.60.50.30.40.40.50.20.40.40.90.41.00.6
Degree of sensitization stereotypy0.90.94.12.01.31.0-0.4-0.70.9-0.01.31.10.50.50.40.90.60.31.20.91.31.00.8
Conditioned locomotion0.10.10.60.00.10.0-0.7-0.7-0.2-0.50.20.2-0.5-0.3-0.8-0.1-0.40.0-0.40.10.1-0.20.1
Cocaine response after cond. corrected0.30.31.4-0.8-1.2-0.60.30.4-0.60.2-0.6-0.4-0.5-0.2-0.7-0.5-0.6-0.0-0.9-0.0-0.5-0.5-0.9
Cocaine response after cond. not corrected0.20.21.0-0.6-1.0-0.30.50.6-0.30.5-0.4-0.3-0.10.1-0.2-0.3-0.30.0-0.50.1-0.3-0.2-0.6
Cocaine response before conditioning0.70.81.80.70.80.90.60.61.00.80.70.71.01.01.30.91.00.51.20.50.91.01.2
Saline control response2.43.26.21.72.02.10.30.31.70.92.32.21.31.71.21.91.31.51.82.52.12.42.4
Bone: connectivity density0.60.93.3-1.8-0.40.01.81.60.61.3-0.8-0.11.00.70.80.41.01.2-0.0-0.7-0.2-0.60.0
Bone: cortical apparent density2.63.55.4-0.21.52.11.81.82.32.11.61.92.22.12.02.12.11.92.01.81.71.91.3
Bone: cortical area0.40.61.5-0.10.50.81.21.21.01.00.40.51.00.91.00.71.00.60.8-0.10.50.30.7
Bone: cortical porosity0.20.21.10.60.7-0.0-0.5-1.1-0.3-0.70.10.2-0.3-0.5-0.80.1-0.10.3-0.2-0.50.1-0.30.4
Bone: cortical porosity0.30.41.70.90.80.0-0.7-1.3-0.3-0.90.30.2-0.5-0.7-0.9-0.0-0.20.0-0.2-0.70.1-0.50.2
Bone: cortical thickness0.71.22.8-0.50.41.01.71.71.31.50.30.61.41.31.50.91.30.81.20.20.70.50.9
Bone: cortical thickness1.41.72.80.11.11.51.41.31.61.40.91.21.61.61.71.41.71.21.50.41.20.81.1
Bone: cortical tissue density2.43.25.0-0.11.52.11.61.62.21.91.61.92.12.01.92.01.91.82.01.81.71.81.3
Condit. Reinf. active minus inactive responses0.40.51.30.50.1-0.5-1.0-1.1-0.8-1.1-0.2-0.5-0.8-0.9-0.8-0.7-0.8-0.8-0.5-0.6-0.7-0.4-0.1
Condit. Reinf. active-inactive response ratio0.10.10.3-0.20.20.20.20.10.10.20.10.10.20.20.30.10.10.10.20.6-0.00.60.6
Condit. Reinf. active responses1.01.23.00.8-0.2-1.1-1.6-1.7-1.2-1.6-0.5-0.9-1.4-1.3-1.2-1.1-1.2-1.4-0.8-0.8-0.8-0.7-0.6
Condit. Reinf. inactive responses0.50.61.20.6-0.3-0.9-1.0-1.1-0.7-1.0-0.4-0.7-0.9-0.9-0.8-0.7-0.7-1.0-0.5-0.7-0.4-0.7-0.9
Incentive salience index mean0.50.71.80.40.1-0.8-1.2-1.2-0.9-1.3-0.4-0.7-1.0-0.9-0.8-0.8-0.8-1.0-0.6-0.6-0.8-0.5-0.1
Condit. Reinf. lever presses0.40.51.50.4-0.0-0.8-1.2-1.2-0.7-1.1-0.4-0.7-0.9-0.8-0.6-0.7-0.7-1.0-0.4-0.3-0.5-0.3-0.2
Condit. Reinf. active minus inactive responses5.47.111.0-0.5-2.5-3.0-2.0-2.1-3.3-2.6-2.5-2.8-3.0-3.0-2.9-3.0-3.0-2.8-3.0-2.2-2.8-2.4-2.3
Condit. Reinf. active-inactive response ratio5.46.39.7-0.3-2.2-2.8-2.4-2.4-3.1-2.6-1.9-2.3-3.1-3.0-3.1-2.7-3.1-2.4-2.9-1.7-2.3-2.1-1.9
Condit. Reinf. active responses5.88.112.70.0-2.0-3.0-2.5-2.6-3.6-3.3-2.4-2.9-3.3-3.3-3.0-3.1-3.1-3.0-3.1-2.6-2.9-2.8-2.4
Condit. Reinf. inactive responses0.91.12.8-0.1-0.5-1.0-0.5-0.6-1.3-1.2-1.2-1.3-0.8-1.1-0.6-1.2-0.7-1.2-1.0-1.7-1.3-1.5-1.1
Condit. Reinf. lever presses1.11.65.21.80.3-0.7-2.1-2.3-1.2-2.00.1-0.4-1.6-1.4-1.7-0.8-1.4-1.0-0.8-0.7-0.3-0.6-0.4
Condit. Reinf. lever reinforcers received4.96.911.00.5-1.7-2.7-2.6-2.8-3.3-3.2-2.0-2.5-3.2-3.1-3.0-2.8-3.0-2.8-2.8-2.2-2.4-2.4-2.1
Conditioned reinforcement - actives0.40.81.70.0-0.0-0.6-0.8-0.8-0.6-1.3-0.5-0.8-1.0-1.0-0.9-0.9-0.7-1.1-0.7-1.1-0.9-1.3-1.0
Conditioned reinforcement - inactives0.10.21.3-0.5-0.10.11.01.10.20.3-0.3-0.30.30.20.6-0.10.3-0.20.1-0.3-0.6-0.40.0
Conditioned locomotion0.20.20.8-0.90.20.00.80.80.60.3-0.3-0.20.20.20.40.10.50.10.1-0.6-0.5-0.6-0.2
Patch foraging indifference point 0 sec1.83.37.11.02.22.41.10.91.81.42.02.42.01.91.12.32.02.71.61.52.01.41.7
Patch foraging indifference point AUC0.30.42.41.60.60.5-1.1-0.80.4-0.60.80.3-0.30.1-0.10.1-0.0-0.60.50.60.70.40.1
Delay disc. indifference point, 0s delay1.21.33.51.71.91.8-0.2-0.61.1-0.11.91.70.50.80.11.20.70.91.00.71.40.50.8
Delay disc. indifference point, 16s delay2.93.27.62.2-0.2-0.9-2.8-2.7-1.9-2.80.2-0.9-2.2-2.0-2.2-1.5-2.2-2.5-1.0-0.8-0.8-0.7-1.2
Delay disc. indifference point, 2s delay2.12.35.21.52.02.30.3-0.11.70.81.92.11.41.50.91.81.51.71.61.12.11.01.1
Delay disc. indifference point, 24s delay0.60.63.11.81.30.7-1.3-1.30.0-1.11.10.5-0.3-0.2-0.30.2-0.1-0.60.60.30.60.20.2
Delay disc. indifference point, 4s delay1.41.55.52.31.81.0-1.6-1.90.1-1.21.91.3-0.4-0.1-0.80.7-0.20.20.61.11.21.01.2
Delay disc. indifference point, 8s delay0.20.21.31.10.70.6-0.5-0.60.1-0.50.80.5-0.10.1-0.10.3-0.0-0.20.40.40.50.4-0.0
Indifference point function ln k0.10.20.6-0.8-0.4-0.60.3-0.0-0.5-0.1-0.5-0.2-0.3-0.6-0.7-0.3-0.40.4-0.8-0.4-0.6-0.2-0.1
Indifference point function log k0.10.20.6-0.8-0.4-0.60.3-0.0-0.5-0.1-0.5-0.2-0.3-0.6-0.7-0.3-0.40.4-0.8-0.4-0.6-0.2-0.1
Patch foraging total patch changes 0 sec1.63.15.51.22.32.30.80.71.71.22.02.31.81.71.02.21.92.41.61.61.91.41.6
Patch foraging total patch changes 12 sec2.53.25.61.72.12.40.40.62.21.12.12.21.71.81.42.11.91.81.91.82.11.51.5
Patch foraging total patch changes 18 sec1.72.64.51.21.72.11.01.11.81.31.71.91.71.81.31.91.81.81.61.61.61.31.5
Patch foraging total patch changes 24 sec1.32.23.80.11.21.81.31.31.61.51.31.71.61.81.21.71.61.91.11.41.41.51.7
Patch foraging total patch changes 6 sec1.82.75.21.61.82.30.60.51.91.11.92.11.61.71.21.91.71.71.71.62.01.51.3
Patch foraging time to switch 0 sec0.00.10.2-0.2-0.4-0.10.40.5-0.20.2-0.2-0.20.0-0.00.1-0.2-0.3-0.1-0.10.4-0.40.3-0.1
Patch foraging water rate 0 sec0.20.51.2-0.00.70.80.50.40.80.70.50.80.90.90.60.91.11.10.60.20.90.40.7
Patch foraging water rate 12 sec0.10.21.0-1.0-0.2-0.30.90.70.00.6-0.5-0.00.40.10.20.20.40.8-0.20.1-0.2-0.20.1
Patch foraging water rate 18 sec0.10.20.6-0.5-0.10.00.80.50.70.7-0.20.10.50.40.50.40.60.60.30.20.30.20.4
Patch foraging water rate 24 sec0.30.42.21.10.90.2-1.1-1.50.1-0.80.70.6-0.3-0.3-0.70.3-0.10.20.20.30.70.10.4
Patch foraging water rate 6 sec0.60.91.9-0.80.40.61.20.90.71.20.10.61.21.01.30.91.21.40.60.90.70.91.1
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.00.20.20.00.10.50.30.10.30.30.40.40.30.40.30.3-0.30.4-0.3-0.2
Distance traveled before self-admin0.60.81.81.11.01.1-0.2-0.30.90.31.31.20.70.70.41.00.60.61.00.91.30.80.5
Distance traveled after self-admin1.92.44.00.01.01.71.51.41.61.81.11.61.91.81.61.71.72.01.31.61.41.31.1
Extensor digitorum longus weight0.41.75.11.82.21.7-0.2-0.41.4-0.02.11.70.70.90.61.40.90.51.70.81.51.31.3
Bone: elastic displacement0.30.31.1-0.9-1.1-0.70.30.4-0.20.4-0.9-0.7-0.1-0.00.2-0.5-0.2-0.3-0.4-0.6-0.5-0.6-0.6
Bone: elastic work1.11.43.1-0.40.21.01.61.61.41.80.60.81.51.61.71.11.40.91.30.71.00.90.8
Bone: endosteal estimation0.10.21.01.00.2-0.1-0.8-0.8-0.2-0.70.50.3-0.6-0.4-0.7-0.1-0.6-0.2-0.20.30.10.20.1
Bone: endosteal perimeter0.10.20.70.60.2-0.1-0.5-0.6-0.4-0.50.20.1-0.5-0.4-0.8-0.1-0.50.1-0.5-0.3-0.2-0.20.1
Epididymis fat weight2.27.610.5-0.9-2.7-3.1-2.1-1.8-3.0-2.6-2.9-3.2-2.9-3.0-2.6-3.2-2.9-3.1-3.0-3.1-3.1-2.5-2.5
Delta time in closed arm before/after self-admin0.00.00.1-0.40.20.1-0.1-0.1-0.1-0.10.30.2-0.1-0.0-0.20.1-0.00.10.00.30.10.2-0.2
Delta time in open arm before/after self-admin0.90.94.22.01.20.9-0.9-1.10.4-0.51.41.0-0.10.2-0.20.60.10.10.80.91.11.10.9
Diff in mean of infusions in LGA sessions0.50.62.0-1.3-0.30.21.41.20.81.2-0.20.30.80.60.70.50.71.10.10.40.00.40.2
Delay discount exponential model param0.91.05.1-2.3-1.2-0.71.61.90.31.4-1.3-0.70.70.41.0-0.10.50.6-0.2-0.3-0.7-0.3-0.1
Extinction: sum of active levers before priming0.20.21.90.3-0.7-0.10.10.0-0.40.0-0.5-0.6-0.10.00.2-0.5-0.2-0.7-0.1-0.6-0.1-0.6-1.4
Active lever presses in extinction session 60.40.40.70.60.60.80.60.60.80.50.40.40.80.70.80.60.90.30.80.40.50.30.2
Bone: final force0.10.20.50.60.70.70.1-0.10.70.20.60.50.50.20.20.50.40.30.6-0.70.6-0.10.2
Bone: final moment0.10.20.60.80.70.6-0.1-0.40.6-0.00.60.50.20.0-0.10.40.20.20.5-0.70.6-0.20.1
Food consumed during 24 hour testing period0.30.41.61.31.00.4-1.0-1.1-0.2-1.10.70.3-0.5-0.4-0.50.1-0.2-0.40.1-0.50.3-0.10.2
Glucose4.06.312.80.9-1.2-2.2-3.6-3.5-2.8-3.3-1.0-1.7-3.3-3.0-3.6-2.4-3.2-2.6-2.4-1.4-1.7-1.4-1.7
Heart weight0.20.30.8-0.3-0.1-0.7-0.5-0.5-0.9-0.8-0.6-0.5-0.5-0.7-0.6-0.6-0.5-0.3-0.7-0.1-0.7-0.3-0.0
Delay discount hyperbolic model param0.80.84.5-2.1-1.2-0.91.31.60.11.1-1.3-0.80.50.20.7-0.30.30.3-0.3-0.4-0.8-0.4-0.3
Intermittent access intake day 1-15 change1.02.04.6-2.1-2.0-1.90.2-0.1-1.5-0.2-1.9-1.5-1.0-1.1-1.0-1.3-1.0-0.4-1.7-1.8-1.4-1.8-1.8
Intermittent access intake escalation0.71.45.5-2.3-1.8-1.60.70.3-1.00.3-1.7-1.1-0.5-0.6-0.5-0.9-0.60.1-1.4-1.5-1.1-1.5-1.5
Intermittent access intake escalation 20.80.94.0-2.0-1.4-1.20.50.3-0.80.3-1.3-0.7-0.4-0.5-0.6-0.6-0.50.3-1.2-1.2-0.9-1.0-1.1
Intermitt. access day 1 inactive lever presses0.10.20.70.60.80.7-0.10.00.5-0.10.60.50.30.20.10.40.30.20.40.40.20.50.7
Intermitt. access day 15 inactive lever presses0.00.10.70.10.30.30.10.30.40.10.10.10.30.20.40.20.30.10.30.20.00.00.8
Intermitt. access escalation Index0.50.83.31.81.20.8-1.1-1.00.5-0.31.41.10.00.3-0.00.70.20.30.80.81.20.60.7
Intermittent access day 1 total infusions0.20.40.9-0.50.50.60.90.90.90.50.10.20.70.71.00.40.90.20.7-0.10.2-0.2-0.0
Intermittent access day 15 total infusions0.30.42.7-1.6-0.5-0.50.90.70.10.5-0.8-0.30.20.20.3-0.10.40.5-0.3-0.9-0.4-1.0-0.9
Intermittent access terminal intake (last 3 days)0.20.21.9-1.4-0.1-0.30.60.40.10.2-0.5-0.10.10.20.10.00.30.4-0.3-0.7-0.2-0.7-0.5
Intermittent access total infusions0.20.21.6-1.3-0.0-0.20.80.70.20.2-0.5-0.20.10.20.4-0.00.40.2-0.1-0.6-0.4-0.7-0.6
Intermittent access day 1 locomotion1.21.53.20.51.51.51.00.91.80.91.11.11.31.51.61.31.70.71.70.61.20.70.5
Intermittent access day 15 total locomotion0.20.30.9-0.60.70.40.90.51.00.30.20.40.50.60.50.60.90.50.5-0.40.3-0.3-0.0
Intermittent access total locomotion0.20.31.1-1.00.30.11.00.70.70.4-0.20.10.40.50.50.30.80.40.3-0.6-0.0-0.6-0.4
Intermittent access standard deviation0.61.32.8-1.7-1.5-1.5-0.1-0.3-1.3-0.5-1.2-1.0-1.0-1.0-1.1-1.1-1.2-0.4-1.5-1.3-1.2-1.1-1.4
Left kidney weight0.83.818.44.33.01.7-2.9-2.50.9-1.92.91.7-0.40.0-0.50.90.0-1.01.81.21.81.51.5
Right kidney weight0.94.220.64.53.32.2-2.4-2.31.3-1.43.32.10.00.5-0.21.40.5-0.42.11.12.31.41.6
Cocaine induced anxiety1.42.02.9-0.8-1.7-1.6-0.8-0.7-1.6-1.0-1.6-1.7-1.2-1.5-1.3-1.6-1.5-1.4-1.6-1.5-1.5-1.3-1.7
Post-drug Anxiety1.51.63.0-1.0-1.6-1.4-0.5-0.5-1.4-0.7-1.6-1.5-0.9-1.2-1.0-1.4-1.1-0.9-1.4-1.7-1.3-1.4-1.5
Baseline Anxiety0.20.20.50.00.70.60.30.30.60.30.50.50.40.50.50.50.60.30.7-0.00.5-0.10.6
Tail length0.10.20.80.40.80.1-0.8-0.90.3-0.60.50.3-0.3-0.2-0.50.20.1-0.00.1-0.60.3-0.8-0.2
Length with tail0.41.88.82.31.60.3-2.5-3.0-0.3-2.01.20.7-1.1-1.0-1.90.1-0.7-0.4-0.1-0.30.7-0.50.1
Length without tail0.41.25.92.11.10.3-1.8-2.4-0.4-1.51.00.7-0.8-0.8-1.60.1-0.7-0.0-0.20.30.60.40.5
Times rat made contact with spout0.40.41.4-0.50.50.60.60.50.60.60.40.80.60.80.60.80.81.20.30.30.70.30.7
Lifetime Intake0.20.20.8-0.90.40.20.80.80.60.3-0.10.10.40.50.60.30.70.20.3-0.4-0.1-0.5-0.2
Liver weight, left0.10.20.90.80.90.4-0.5-0.3-0.1-0.50.40.3-0.00.1-0.00.20.20.10.2-0.00.1-0.10.5
Liver weight, right0.30.52.61.01.61.10.0-0.10.5-0.31.00.90.40.50.30.80.70.50.7-0.00.6-0.20.7
Locomotor activity0.30.52.81.70.90.5-1.1-1.1-0.1-1.10.90.3-0.6-0.3-0.5-0.0-0.4-0.70.3-0.00.3-0.3-0.2
Locomotor testing distance0.20.42.01.40.80.6-0.8-0.70.1-0.70.90.4-0.4-0.2-0.40.1-0.3-0.60.40.40.30.10.0
Locomotor testing rearing0.20.51.41.21.01.0-0.1-0.10.90.11.20.80.40.60.40.70.4-0.11.10.70.90.30.2
Locomotion in novel chamber1.62.03.50.01.31.51.20.91.91.41.11.61.61.61.31.71.71.91.31.21.41.31.5
Locomotion in novel chamber post-restriction0.40.71.4-0.40.80.80.80.80.80.70.60.80.90.90.90.91.01.10.60.70.60.61.2
Fecal boli incidents, locomotor time 10.81.12.2-0.3-1.0-1.3-0.8-0.7-1.5-1.1-0.9-1.2-1.3-1.2-0.9-1.3-1.4-1.5-1.0-0.3-1.2-0.5-0.7
Change in fecal boli incidents, locomotor task1.41.44.0-1.30.10.92.01.81.31.7-0.10.71.51.41.11.11.61.70.4-0.40.4-0.3-0.1
Time >=10cm from walls, locomotor time 10.20.32.0-0.60.10.20.40.20.10.50.00.50.50.2-0.10.50.21.4-0.30.90.10.40.6
Bouts of movement, locomotor time 10.20.20.50.60.60.3-0.5-0.6-0.1-0.70.60.2-0.4-0.1-0.30.1-0.2-0.60.30.20.30.20.3
Total resting periods, locomotor time 10.10.10.50.40.50.1-0.5-0.5-0.3-0.70.50.1-0.5-0.2-0.2-0.0-0.2-0.60.20.30.10.30.4
Rest time, locomotor task time 11.11.42.3-0.5-1.3-1.4-0.6-0.4-1.4-1.0-1.1-1.4-1.3-1.2-0.9-1.4-1.2-1.5-1.1-1.2-1.3-1.1-1.3
Distance moved, locomotor task time 12.03.05.51.32.22.30.40.42.00.92.02.11.71.61.12.01.71.91.71.91.91.72.0
Vertical activity count, locomotor time 11.84.36.8-0.11.72.52.12.02.52.31.62.12.62.42.12.32.42.62.01.81.91.51.7
Time >=10cm from walls, locomotor time 20.71.14.8-2.2-1.00.01.91.6-0.01.6-0.80.21.00.60.40.40.51.9-0.70.1-0.2-0.00.0
Bouts of movement, locomotor time 20.30.51.81.20.60.1-1.2-1.0-0.5-1.30.6-0.1-1.0-0.6-0.7-0.4-0.7-1.20.10.2-0.20.30.1
Total resting periods, locomotor time 20.50.82.61.40.5-0.1-1.5-1.3-0.7-1.60.5-0.2-1.2-0.8-1.0-0.6-1.0-1.4-0.20.0-0.30.1-0.1
Rest time, locomotor task time 20.91.22.20.2-0.8-1.1-1.2-1.1-1.4-1.3-0.6-1.0-1.3-1.3-1.2-1.2-1.3-1.5-1.0-0.9-1.0-0.6-1.0
Distance moved, locomotor task time 22.22.74.71.22.12.20.60.51.81.01.92.11.61.61.11.91.61.91.71.51.91.41.8
Vertical activity count, locomotor time 20.71.02.00.20.81.40.80.81.21.11.01.21.21.20.81.10.91.30.90.71.10.80.9
Light reinforcement 10.71.74.40.9-0.1-0.9-2.1-2.1-1.4-2.1-0.3-0.8-1.6-1.5-1.8-1.1-1.5-1.4-1.1-0.7-0.8-0.6-0.7
Light reinforcement 21.93.05.7-1.9-2.2-2.2-0.20.1-1.9-0.7-2.4-2.0-1.3-1.5-1.3-1.8-1.5-0.9-2.2-1.9-2.3-2.0-1.7
Bone: marrow area0.10.21.01.00.30.0-0.7-0.7-0.1-0.50.60.4-0.5-0.3-0.60.0-0.5-0.1-0.10.40.20.30.1
Bone: maximum diameter0.00.10.3-0.1-0.2-0.10.10.2-0.1-0.1-0.2-0.2-0.2-0.2-0.3-0.2-0.2-0.0-0.3-0.5-0.3-0.4-0.0
Bone: maximum force0.50.81.60.71.01.20.50.31.30.81.11.11.00.80.71.10.90.81.20.21.20.60.8
Bone: maximum moment0.30.61.30.91.01.10.3-0.01.10.51.11.00.70.60.40.90.70.61.00.11.10.40.6
Mean time between licks in bursts0.40.94.0-2.0-1.1-0.41.71.9-0.01.4-1.1-0.50.80.71.1-0.00.50.7-0.2-0.2-0.5-0.0-0.4
Mean num. licks in bursts0.30.52.6-1.6-1.1-0.60.50.6-0.20.4-1.1-0.8-0.1-0.20.0-0.5-0.1-0.3-0.5-0.5-0.7-1.0-1.2
Cd content in liver0.00.10.30.00.10.10.40.20.10.3-0.00.20.20.1-0.10.20.10.5-0.1-0.5-0.0-0.20.3
Co content in liver1.71.97.8-2.8-2.0-1.21.81.8-0.11.7-2.1-1.20.80.31.1-0.50.50.5-0.6-1.7-0.8-1.4-0.8
Cu content in liver7.89.215.3-0.02.32.93.03.13.53.42.22.83.53.63.93.23.63.03.42.42.92.93.0
Fe content in liver0.50.62.7-1.0-0.50.11.71.60.61.2-0.2-0.10.70.81.30.20.60.10.50.4-0.00.60.4
K content in liver0.10.10.40.0-0.0-0.2-0.40.10.0-0.2-0.1-0.3-0.20.00.3-0.2-0.0-0.60.2-0.1-0.10.0-0.3
Mg content in liver0.20.20.7-0.5-0.10.10.50.80.40.7-0.2-0.00.60.50.80.20.60.30.4-0.10.10.1-0.0
Mn content in liver0.70.81.61.31.21.0-0.2-0.20.90.21.11.00.60.70.70.90.90.51.11.01.21.00.8
Na content in liver5.25.58.9-1.5-2.6-2.7-1.3-1.0-2.4-1.7-2.6-2.9-2.2-2.3-1.8-2.8-2.3-2.7-2.4-2.5-2.7-2.5-3.0
Rb content in liver1.31.67.1-2.7-1.8-0.92.02.3-0.31.7-1.6-0.80.70.61.1-0.30.40.8-0.70.6-0.80.20.2
Se content in liver0.20.30.9-0.7-0.5-0.30.70.90.20.6-0.5-0.60.40.41.0-0.20.3-0.40.40.4-0.30.2-0.1
Sr content in liver1.61.42.5-0.2-0.6-1.1-1.4-1.6-1.3-1.4-0.9-1.0-1.3-1.4-1.5-1.2-1.2-1.0-1.3-1.2-1.1-1.3-0.9
Zn content in liver1.01.12.80.71.51.20.40.40.80.41.31.30.90.90.81.21.01.21.00.51.01.21.7
Bone: minimum diameter0.00.10.40.10.10.20.50.60.40.20.30.20.10.20.20.20.00.10.20.0-0.00.30.2
Time in familiar zone, hab. session 10.30.31.6-0.9-1.3-0.70.40.5-0.60.4-0.7-0.5-0.2-0.1-0.2-0.5-0.6-0.0-0.70.5-0.50.1-0.1
Time in novel zone, hab. session 10.20.20.7-0.80.10.20.80.60.30.3-0.2-0.10.40.10.50.10.40.10.2-0.8-0.3-0.3-0.4
Total zone transitions, hab. session 10.20.31.40.70.5-0.0-1.2-1.0-0.4-0.90.40.2-0.5-0.3-0.6-0.1-0.4-0.3-0.10.50.10.30.4
Total locomotion distance, hab. session 10.40.51.91.41.00.7-0.9-0.80.1-0.61.10.7-0.10.30.00.50.1-0.00.61.00.80.90.7
Locomotion velocity, hab. session 10.60.92.91.71.40.9-1.2-1.10.3-0.61.41.0-0.00.30.00.70.20.10.81.21.11.10.9
Time in familiar zone, hab. session 20.30.31.5-1.1-1.2-0.51.01.0-0.30.6-0.5-0.4-0.10.0-0.1-0.3-0.40.1-0.60.1-0.6-0.0-0.1
Time in novel zone, hab. session 20.10.10.60.60.80.2-0.5-0.70.2-0.60.20.0-0.0-0.2-0.10.10.2-0.30.3-0.50.2-0.4-0.3
Total zone transitions, hab. session 20.10.20.7-0.20.90.30.0-0.00.2-0.10.40.60.20.2-0.20.50.40.80.10.30.20.30.8
Total locomotion distance, hab. session 20.91.23.61.21.91.2-0.3-0.30.7-0.21.61.50.50.60.21.20.71.00.91.51.11.31.5
Locomotion velocity, hab. session 20.91.33.31.01.81.2-0.2-0.20.70.01.51.50.70.70.41.20.81.21.01.61.11.51.6
Novel to familiar place preference ratio0.50.51.71.21.30.5-1.2-0.9-0.2-1.10.90.5-0.4-0.2-0.50.2-0.2-0.10.20.50.10.70.9
Novelty place preference0.40.41.71.11.30.5-1.0-0.7-0.1-0.90.90.6-0.3-0.1-0.30.3-0.0-0.00.30.50.20.71.1
Time in novel zone, NPP test0.30.41.30.80.90.2-1.1-0.8-0.5-1.10.50.2-0.6-0.4-0.7-0.1-0.4-0.3-0.10.1-0.20.30.7
Total zone transitions, NPP test1.01.42.7-0.9-1.3-1.5-0.6-0.6-1.3-0.9-1.5-1.4-1.1-1.2-1.1-1.3-1.0-0.8-1.5-1.3-1.3-1.6-1.1
Total locomotion distance, NPP test0.50.71.91.21.40.9-0.5-0.40.6-0.11.21.20.30.50.10.90.60.80.70.81.10.71.0
Locomotion velocity, NPP test0.50.71.81.21.30.9-0.4-0.30.70.11.11.10.50.60.41.00.80.80.90.91.10.81.0
Intraocular pressure0.20.31.21.01.10.7-0.3-0.00.1-0.10.90.80.30.40.20.60.40.40.50.80.6-0.00.4
Delta distance traveled before/after self-admin0.50.52.6-1.3-0.60.11.61.40.21.1-0.6-0.10.80.50.60.20.50.9-0.20.5-0.40.30.3
Delta ambulatory time before/after self-admin0.20.31.7-0.8-0.40.11.31.00.10.8-0.4-0.00.60.40.40.20.30.7-0.20.4-0.30.10.1
Parametrial fat weight3.17.29.5-1.0-2.3-3.1-2.0-1.9-3.0-2.7-2.6-2.9-2.9-3.1-2.8-3.0-2.8-2.7-2.9-2.7-2.9-2.9-2.8
Pavlov. Cond. lever latency0.20.20.7-0.4-0.7-0.00.90.80.30.8-0.4-0.20.50.20.4-0.00.20.10.0-0.5-0.0-0.4-0.5
Pavlov. Cond. magazine entry latency0.10.20.9-0.9-0.7-0.40.20.2-0.40.2-0.5-0.4-0.1-0.1-0.2-0.3-0.30.0-0.50.6-0.50.2-0.0
Pavlov. Cond. change in total contacts0.40.40.9-0.6-0.3-0.7-0.6-0.6-0.7-0.8-0.6-0.7-0.7-0.8-0.8-0.7-0.7-0.6-0.8-0.3-0.9-0.6-0.4
Pavlov. Cond. index score0.10.10.3-0.6-0.1-0.3-0.3-0.3-0.4-0.3-0.2-0.2-0.3-0.2-0.4-0.2-0.40.1-0.40.6-0.40.20.2
Pavlov. Cond. latency score0.10.10.3-0.4-0.0-0.4-0.5-0.5-0.6-0.5-0.2-0.2-0.4-0.3-0.5-0.3-0.4-0.1-0.50.5-0.40.20.1
Pavlov. Cond. lever contacts0.10.10.40.10.60.1-0.4-0.40.0-0.30.40.4-0.10.1-0.10.30.10.30.20.70.20.60.6
Pavlov. Cond. magazine entry number0.20.21.51.20.70.6-0.4-0.30.4-0.20.70.50.10.20.20.40.3-0.10.6-0.20.70.10.1
Pavlov. Cond. intertrial magazine entries0.30.41.20.1-0.4-0.7-0.3-0.6-0.4-0.6-0.6-0.7-0.6-0.6-0.4-0.6-0.4-0.7-0.4-1.1-0.5-0.9-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.3-0.1-0.3-0.5-0.5-0.4-0.4-0.1-0.2-0.4-0.3-0.4-0.2-0.4-0.1-0.40.6-0.30.20.1
Pavlov. Cond. response bias0.10.10.2-0.5-0.1-0.4-0.2-0.3-0.4-0.3-0.2-0.2-0.3-0.3-0.4-0.3-0.40.0-0.40.3-0.40.10.3
Pavlov. Cond. lever latency1.52.08.1-2.8-1.30.02.82.80.82.1-1.0-0.51.41.31.70.21.10.60.20.6-0.50.1-0.4
Pavlov. Cond. magazine entry latency0.20.21.00.41.00.4-0.1-0.30.2-0.20.60.80.1-0.0-0.50.60.31.0-0.1-0.30.20.00.8
Pavlov. Cond. change in total contacts0.91.45.32.11.1-0.2-2.1-2.3-0.9-1.90.70.3-1.3-1.2-1.6-0.3-0.9-0.4-0.5-0.70.1-0.30.1
Pavlov. Cond. index score0.91.24.42.11.60.4-1.8-2.0-0.2-1.41.21.0-0.7-0.7-1.30.4-0.40.40.0-0.20.70.30.9
Pavlov. Cond. latency score0.70.93.61.91.60.6-1.4-1.60.0-1.01.21.1-0.4-0.4-1.00.6-0.10.70.1-0.10.80.41.0
Pavlov. Cond. lever contacts1.72.39.02.91.3-0.1-3.0-3.0-0.9-2.31.10.4-1.5-1.4-1.9-0.3-1.2-0.7-0.3-0.80.4-0.30.2
Pavlov. Cond. magazine entry number0.50.62.5-1.6-1.3-0.41.21.4-0.01.0-1.0-0.80.40.40.9-0.40.2-0.2-0.10.2-0.5-0.1-0.5
Pavlov. Cond. intertrial magazine entries1.92.96.6-1.2-2.6-2.2-0.6-0.4-2.0-0.8-2.2-2.3-1.5-1.4-0.7-2.1-1.7-2.0-1.7-1.0-1.8-1.4-2.1
Pavlov. Cond. lever-magazine prob. diff.0.91.14.42.11.60.5-1.8-1.9-0.2-1.31.31.0-0.7-0.6-1.20.4-0.40.30.1-0.10.70.40.9
Pavlov. Cond. response bias1.21.66.22.51.40.1-2.4-2.4-0.6-1.91.00.5-1.2-1.1-1.6-0.1-0.9-0.4-0.2-0.70.3-0.10.4
Time in closed arm before self-admin0.40.61.7-0.7-0.40.21.11.10.91.3-0.30.11.00.91.20.50.90.80.50.30.40.30.2
Time in closed arm after self-admin0.70.71.5-0.70.20.81.00.80.91.20.40.71.11.00.90.91.01.10.70.70.80.80.6
Time in open arm before self-admin0.40.51.2-0.0-0.1-0.5-0.9-1.1-0.9-1.0-0.3-0.4-0.7-0.9-0.9-0.6-0.7-0.5-0.7-0.6-0.4-0.7-0.5
Time in open arm after self-admin0.10.10.20.10.0-0.2-0.1-0.3-0.3-0.5-0.2-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.3-0.2-0.4-0.10.0
Bone: periosteal estimation0.10.20.80.90.50.5-0.1-0.10.4-0.00.80.60.00.20.00.30.00.10.40.30.40.50.4
Bone: periosteal perimeter0.00.00.20.40.10.30.20.20.10.10.30.30.00.2-0.10.2-0.00.10.1-0.00.10.10.2
Bone: post-yield work0.91.32.5-0.3-0.9-1.1-0.6-0.8-1.1-1.0-0.9-1.0-1.3-1.4-1.6-1.2-1.3-0.9-1.3-1.4-1.1-1.3-1.2
Progressive ratio test 1 active lever presses0.20.30.90.20.90.50.40.40.90.10.20.20.50.60.90.41.0-0.10.9-0.30.4-0.40.2
Progressive ratio test 1 breakpoint0.30.30.90.20.90.50.40.40.90.10.30.20.50.60.90.41.0-0.10.9-0.30.4-0.40.2
Progressive ratio test 1 inactive lever presses1.11.54.41.72.11.80.10.11.40.01.71.20.91.01.11.11.20.11.81.01.20.81.2
Progressive ratio test 2 active lever presses0.30.30.9-0.10.90.60.70.40.90.20.20.30.50.60.70.50.90.30.7-0.40.2-0.40.4
Progressive ratio test 2 breakpoint0.30.41.1-0.01.10.60.80.40.90.20.30.40.50.60.70.61.00.40.7-0.30.3-0.30.5
Progressive ratio test 2 inactive lever presses1.21.94.0-0.21.21.51.61.62.01.40.81.11.71.71.91.41.91.21.60.81.00.61.2
Incentive Sensitization - Responses0.20.31.7-0.6-0.1-0.50.50.2-0.3-0.4-0.7-0.5-0.3-0.4-0.3-0.4-0.1-0.2-0.5-1.1-0.9-1.3-0.5
Incentive Sensitization - Breakpoint0.10.21.0-0.50.1-0.20.60.3-0.1-0.2-0.4-0.3-0.2-0.2-0.1-0.20.10.0-0.3-0.9-0.7-1.0-0.2
Sum of active levers in priming session hrs 5-60.20.20.7-0.4-0.40.10.80.80.10.5-0.4-0.30.40.30.6-0.10.3-0.00.0-0.3-0.2-0.4-0.4
Progressive ratio1.32.03.40.61.81.61.21.11.71.01.31.51.51.51.51.61.71.51.51.01.20.81.6
Food seeking constrained by brief footshock0.40.51.21.01.10.8-0.2-0.30.7-0.00.90.80.40.40.20.70.50.40.70.70.70.81.1
Seeking ratio, punishment vs. effort1.01.52.70.0-1.1-1.2-1.5-1.4-1.6-1.3-0.8-1.1-1.5-1.4-1.6-1.3-1.6-1.3-1.3-0.6-0.9-0.4-1.1
Retroperitoneal fat weight6.427.437.2-2.1-5.2-6.1-3.6-3.5-5.7-4.5-5.7-6.0-5.1-5.6-4.9-5.9-5.1-5.2-5.6-6.1-5.4-5.8-5.7
Reaction time number correct0.10.20.5-0.50.1-0.30.3-0.2-0.3-0.5-0.3-0.3-0.3-0.5-0.5-0.3-0.3-0.1-0.5-0.3-0.7-0.5-0.2
Reaction time mean minus median2.05.010.0-0.6-2.0-2.2-1.0-1.0-2.2-1.9-2.1-2.5-2.2-2.2-1.9-2.5-2.1-2.6-2.2-3.2-2.5-3.0-2.9
Reaction time mean minus median AUC1.64.08.7-1.2-2.0-2.1-0.3-0.4-2.0-1.4-2.2-2.4-1.7-1.8-1.5-2.2-1.7-2.0-2.1-3.0-2.4-2.8-2.7
Reaction time num false alarms0.30.41.0-1.0-0.4-0.00.81.00.31.0-0.7-0.10.80.50.70.20.70.9-0.0-0.1-0.0-0.0-0.1
Reaction time num false alarms AUC0.10.10.3-0.3-0.10.00.30.40.30.6-0.3-0.00.60.30.50.20.50.50.10.00.10.0-0.0
Reaction time trials correct on left0.10.20.5-0.50.1-0.30.3-0.2-0.3-0.5-0.3-0.3-0.3-0.5-0.5-0.3-0.3-0.1-0.5-0.3-0.7-0.5-0.2
Reaction time trials on left0.10.20.6-0.60.1-0.30.4-0.1-0.4-0.5-0.4-0.3-0.3-0.5-0.5-0.3-0.2-0.1-0.5-0.3-0.8-0.5-0.2
Reaction time mean0.20.30.9-0.2-0.5-0.20.50.7-0.00.1-0.6-0.7-0.00.10.6-0.50.1-0.80.0-0.9-0.5-0.9-1.0
Reaction time mean AUC0.30.51.6-0.4-0.7-0.50.40.6-0.3-0.1-0.9-1.0-0.3-0.20.3-0.8-0.1-1.1-0.2-1.3-0.8-1.2-1.2
Median of all reaction times0.30.41.6-0.10.00.50.91.10.70.9-0.00.00.70.91.30.30.90.00.80.00.30.0-0.1
Reaction time omissions0.20.30.8-0.8-0.5-0.00.90.90.00.7-0.5-0.30.50.50.8-0.00.50.00.1-0.6-0.2-0.3-0.8
Reaction time false alarm rate0.10.20.7-0.4-0.40.00.30.70.30.8-0.4-0.00.70.50.70.20.50.60.20.10.20.20.0
Reaction time premature initiation rate1.82.47.10.2-0.8-1.3-1.5-1.5-1.5-1.7-1.1-1.2-1.7-1.6-1.7-1.4-1.3-1.1-1.7-2.5-1.1-2.7-1.9
Reaction time premature initiations1.32.27.00.1-0.6-1.2-1.2-1.5-1.4-1.7-1.1-1.1-1.6-1.6-1.8-1.3-1.2-0.9-1.7-2.4-1.2-2.7-1.7
Std. dev. reaction times1.22.26.2-0.6-1.4-1.4-0.2-0.2-1.2-0.9-1.7-1.9-1.1-1.1-0.7-1.6-0.9-1.9-1.2-2.5-1.7-2.3-2.2
Reaction time trials completed0.10.20.6-0.60.1-0.30.4-0.1-0.4-0.5-0.4-0.3-0.3-0.5-0.5-0.3-0.2-0.1-0.5-0.3-0.8-0.5-0.2
Reaction time trials AUC0.10.10.4-0.60.2-0.20.5-0.1-0.2-0.4-0.2-0.2-0.2-0.4-0.4-0.2-0.10.0-0.3-0.2-0.6-0.4-0.1
Run reversals in cocaine runway, females2.02.04.31.0-1.1-1.2-1.8-1.6-1.5-1.6-0.5-1.2-1.8-1.5-1.5-1.5-1.8-2.1-1.1-1.0-0.9-0.9-1.4
Run reversals in cocaine runway, males0.10.10.60.5-0.10.3-0.2-0.8-0.5-0.2-0.00.00.1-0.3-0.2-0.0-0.20.0-0.10.40.40.50.1
Latency to leave start box in cocaine runway0.70.81.9-0.9-1.1-1.4-0.5-0.3-1.0-0.5-1.3-1.2-0.8-0.8-0.4-1.0-0.6-0.7-0.9-0.9-0.9-0.7-0.8
Latency to leave start box in cocaine runway, F0.50.61.4-0.5-0.9-1.0-0.8-0.7-1.2-0.7-0.8-0.8-0.9-0.8-0.6-0.9-0.9-0.7-0.9-0.5-0.6-0.3-0.5
Latency to leave start box in cocaine runway, M0.20.20.7-0.5-0.4-0.80.00.20.10.1-0.8-0.6-0.1-0.30.2-0.40.1-0.2-0.2-0.7-0.5-0.7-0.5
Std. dev. time between licks in bursts0.10.10.30.2-0.3-0.2-0.20.1-0.1-0.0-0.3-0.4-0.1-0.00.2-0.3-0.0-0.40.0-0.6-0.1-0.6-0.5
Total sessions with >9 infusions0.40.51.2-0.30.40.61.01.11.10.70.20.20.70.91.10.51.00.10.8-0.20.3-0.40.0
Short access day 1 total inactive lever presses0.10.10.6-0.40.30.20.80.80.30.20.10.10.30.30.30.20.30.20.20.4-0.20.30.7
Short access day 10 total inactive lever presses1.63.97.10.1-1.4-2.0-2.0-1.7-2.7-2.4-1.3-1.9-2.3-2.4-2.3-2.2-2.5-2.4-2.0-1.4-1.9-1.2-1.6
Short access day 1 total infusions0.10.10.5-0.7-0.3-0.30.30.50.10.0-0.3-0.3-0.2-0.0-0.1-0.2-0.1-0.1-0.4-0.3-0.5-0.3-0.2
Short access day 10 total infusions1.01.32.8-0.40.81.21.41.71.61.30.70.81.31.51.61.01.40.81.20.80.70.80.7
Short access total infusions0.30.31.0-0.50.50.50.80.91.00.50.20.20.50.70.90.50.90.20.60.10.2-0.10.3
Short access day 1 locomotion0.10.10.4-0.3-0.4-0.10.30.30.0-0.2-0.2-0.3-0.3-0.2-0.3-0.4-0.3-0.6-0.3-0.6-0.5-0.5-0.4
Short access day 10 total locomotion0.50.93.7-0.9-0.40.51.71.91.01.5-0.00.11.01.11.50.40.90.30.80.60.10.70.0
Short access total locomotion0.20.31.0-0.8-0.6-0.20.91.00.30.4-0.6-0.60.10.20.5-0.30.2-0.5-0.0-0.6-0.5-0.5-0.5
One hour access (0.3 mA shock)0.10.10.60.10.80.40.10.10.4-0.20.30.20.00.20.10.20.40.10.3-0.30.0-0.5-0.1
Compulsive drug intake1.82.29.53.12.11.5-1.8-1.40.6-0.92.21.50.10.2-0.20.90.10.01.22.01.41.91.3
One hour access (shock baseline)0.71.15.5-2.3-0.9-0.51.91.70.41.1-1.2-0.60.50.50.7-0.10.70.6-0.4-1.2-0.7-1.3-0.9
Social response proportion0.70.84.4-2.1-1.4-0.81.31.1-0.41.0-1.3-0.60.30.20.4-0.30.10.7-0.8-0.4-0.7-0.2-0.5
Social responses0.10.20.5-0.6-0.6-0.20.70.60.10.6-0.5-0.30.20.20.4-0.10.10.1-0.1-0.7-0.2-0.6-0.6
Social time0.30.41.9-1.4-1.0-0.40.70.8-0.30.8-0.9-0.40.30.10.3-0.20.10.5-0.5-0.8-0.4-0.4-0.4
Soleus weight1.13.19.32.63.02.2-0.4-0.61.70.02.62.21.11.20.91.91.51.12.10.92.21.51.8
Bone: stiffness0.20.31.20.61.10.7-0.1-0.20.70.00.80.70.40.30.20.60.50.40.7-0.20.70.20.5
Tibialis anterior weight0.20.82.61.00.7-0.1-1.5-1.6-0.6-1.60.3-0.1-1.0-1.0-1.3-0.4-0.8-0.8-0.3-1.2-0.3-0.7-0.5
Time to tail flick, vehicle, before self-admin0.60.61.50.91.20.9-0.10.10.90.21.00.90.50.70.70.80.70.41.00.80.80.81.0
Time to tail flick, vehicle, after self-admin0.71.02.10.51.41.10.20.11.10.41.31.30.70.70.51.20.91.01.01.31.01.01.1
Time to tail flick, test, before self-admin2.72.86.6-1.20.71.61.91.91.42.20.51.42.22.01.81.72.02.61.11.61.21.61.4
Time to tail flick, test, after self-admin0.80.84.4-2.1-1.0-0.51.31.2-0.01.0-1.3-0.70.70.30.8-0.20.60.5-0.3-0.6-0.5-0.7-0.6
Delta time to tail flick, vehicle, before/after SA0.10.10.30.30.40.40.0-0.10.30.10.50.60.20.1-0.10.40.20.50.20.40.40.10.3
Delta time to tail flick, test, before/after SA4.74.87.5-1.1-2.1-2.7-1.0-1.0-2.2-1.7-2.3-2.5-2.3-2.3-1.9-2.5-2.1-2.5-2.1-2.7-2.4-2.6-2.4
Tibia length0.41.22.50.6-0.3-0.7-1.5-1.2-1.1-1.4-0.4-0.7-1.2-1.3-1.6-0.9-1.2-0.9-1.1-1.4-0.8-1.1-1.0
Ambulatory time before self-admin0.30.41.11.00.80.7-0.4-0.50.60.10.90.80.50.40.30.70.50.30.80.61.00.50.4
Ambulatory time after self-admin1.61.83.7-0.80.41.11.91.61.41.90.41.01.91.61.51.41.61.90.91.20.90.90.9
Bone: tissue strength1.31.42.5-1.3-1.5-1.4-0.00.1-0.8-0.3-1.5-1.5-0.8-1.0-0.8-1.2-0.9-0.9-1.2-1.6-1.5-1.5-1.4
Total heroin consumption1.41.74.01.91.81.6-0.3-0.31.40.12.01.60.70.90.61.30.80.51.51.61.51.71.0
Bone: trabecular number0.81.32.40.01.01.21.21.01.51.30.81.01.51.31.41.31.51.21.40.51.20.61.0
Bone: trabecular spacing1.21.62.70.3-0.8-1.2-1.5-1.3-1.6-1.6-0.7-1.0-1.6-1.6-1.6-1.3-1.6-1.3-1.5-0.7-1.2-0.8-0.8
Bone: trabecular thickness3.13.97.2-1.20.91.62.72.52.22.70.61.52.62.42.52.02.62.61.70.61.50.91.4
Bone: trabecular tissue density2.74.06.01.02.12.30.70.82.11.62.32.42.12.11.92.32.01.92.32.22.42.42.0
Water consumed over 24 hours0.30.40.80.00.90.80.30.50.90.40.60.70.60.80.70.70.90.50.7-0.30.60.10.5
Number of responses in last shaping day1.01.12.8-0.11.21.20.91.01.20.80.91.31.01.10.81.31.21.50.70.70.80.61.7