Vegfa

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	RMTg	alternative TSS	NM_031836.3	0.17	0.11	6.7e-03	0.11	0.09	0.09	0.1	7.8e-04	2.4e-03	2.1e-03	1.2e-03
2	PL	intron excision ratio	chr9_14956379_14959271	0.03	0.02	8.8e-03	0.01	0.01	0.01	0.01	1.6e-02	4.0e-02	3.9e-02	6.5e-02
3	PL	isoform ratio	NM_001110336.1	0.02	0.01	7.8e-03	0.01	0.01	0	0	3.0e-02	4.9e-02	2.9e-01	1.6e-01
4	NAcc	mRNA stability	Vegfa	0.02	0.02	6.1e-03	0	0.01	-0	0	3.6e-01	2.4e-02	4.3e-01	1.6e-01
5	LHb	gene expression	Vegfa	0.19	0.1	8.0e-04	0.06	0.12	0.03	0.09	1.2e-02	8.9e-04	7.9e-02	4.0e-03
6	LHb	isoform ratio	NM_001110336.1	0.17	0.13	6.8e-03	0.06	0.07	0.03	0.05	1.6e-02	8.7e-03	8.0e-02	2.1e-02
7	Adipose	gene expression	Vegfa	0.19	0.09	0.0e+00	0.19	0.19	0.19	0.19	1.3e-20	7.4e-21	8.0e-21	1.2e-20
8	Brain	isoform ratio	NM_001287107.1	0.04	0.03	1.6e-04	0.04	0.04	0.04	0.04	2.5e-04	8.4e-05	1.1e-04	2.1e-04
9	Brain	isoform ratio	NM_031836.3	0.04	0.03	1.6e-04	0.04	0.04	0.04	0.04	2.5e-04	8.4e-05	1.1e-04	2.1e-04
10	Liver	mRNA stability	Vegfa	0.02	0.01	6.1e-03	0.02	0.02	0.02	0.02	3.9e-03	3.2e-03	2.5e-03	2.6e-03
11	NAcc	gene expression	Vegfa	0.16	0.08	1.2e-03	0	0.02	0.02	0	2.2e-01	9.3e-04	2.6e-03	2.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.1	0.2	0.4	0.3	-0.7	0.3	0.6	0.4	0.1	0.4	-0.6	-0.6	-0.0	-0.2
Area under the delay curve	3.0	3.2	8.0	-2.8	-1.8	2.0	-1.4	-1.4	-1.8	-1.3	1.6	1.6	1.9	-1.4
BMI with tail	0.7	2.1	16.8	0.6	4.1	-0.2	-0.8	0.0	0.8	0.3	-0.3	-0.3	-1.9	-1.0
BMI without tail	2.7	5.6	27.9	1.3	5.3	-1.3	-0.2	1.2	2.1	1.6	-1.6	-1.6	-3.5	-2.1
Body weight	1.1	4.8	15.1	2.2	3.9	-1.4	1.1	1.8	2.4	1.9	-2.0	-2.0	-2.9	-0.5
Weight adjusted by age	0.2	0.2	0.5	-0.7	-0.0	0.6	-0.5	-0.4	-0.5	-0.3	0.3	0.3	0.4	-0.5
Bone surface	0.5	0.8	4.7	-0.7	-2.2	1.1	0.2	-0.3	-0.9	-0.4	0.2	0.2	1.2	-0.3
Bone volume	0.3	0.5	2.4	-0.4	-1.5	0.9	0.1	-0.3	-0.7	-0.4	0.2	0.2	1.0	-0.0
Breakpoint value in progressive ratio session	0.6	0.6	1.4	-1.1	-0.6	0.8	-0.7	-0.6	-0.8	-0.6	0.7	0.7	0.6	-1.2
Number of licking bursts	1.2	1.4	2.3	1.5	0.9	-0.4	1.2	1.3	1.3	1.3	-1.5	-1.5	-1.2	-0.4
Context. condit. distance diff. score	0.5	0.6	3.7	0.7	1.9	-0.1	-0.4	-0.1	0.3	-0.0	-0.2	-0.2	-1.3	0.1
Locomotion velocity, session 1	1.4	1.5	2.6	-1.6	-0.8	1.5	-1.3	-1.3	-1.4	-1.2	1.3	1.3	1.0	-0.6
Locomotion distance, session 1	0.6	0.8	1.6	-0.5	0.1	1.3	-1.2	-1.1	-1.0	-1.1	0.8	0.8	0.3	0.1
Locomotion velocity, session 2	0.4	0.5	2.5	-0.3	1.6	0.5	-1.0	-0.4	-0.1	-0.2	0.1	0.1	-1.0	-0.8
Locomotion distance, session 2	0.6	0.8	1.9	-0.8	0.4	1.2	-1.4	-1.1	-1.0	-1.0	0.8	0.8	-0.0	-0.5
Locomotion velocity, session 3	0.8	1.0	1.7	-1.1	-0.0	0.8	-1.3	-1.2	-1.1	-1.1	1.2	1.2	0.6	-0.4
Locomotion distance, session 3	0.8	0.8	1.3	-0.8	-0.4	0.9	-0.9	-1.0	-1.0	-1.1	1.1	1.1	0.8	0.3
Stereotopy head waving bouts, day 3	0.2	0.3	0.7	0.8	0.1	-0.3	0.6	0.5	0.6	0.4	-0.5	-0.5	0.0	0.8
Stereotopy head waving duration, day 3	0.1	0.1	0.7	0.2	0.9	0.0	-0.4	-0.3	-0.0	-0.2	0.2	0.2	-0.1	0.4
Locomotion velocity, session 7	1.0	1.1	1.6	-0.6	-1.2	0.6	-0.7	-1.0	-1.1	-1.2	1.2	1.2	1.3	1.1
Locomotion distance, session 7	1.6	2.1	3.2	-1.2	-0.4	1.4	-1.6	-1.7	-1.6	-1.8	1.7	1.7	1.5	0.6
Stereotopy head waving bouts, day 7	0.4	0.5	1.6	0.7	1.3	0.1	-0.1	0.3	0.5	0.4	-0.6	-0.6	-1.3	0.3
Stereotopy head waving duration, day 7	0.5	0.6	1.3	1.0	0.6	-0.3	0.6	0.7	0.8	0.7	-0.9	-0.9	-1.1	0.4
Locomotion velocity, session 8	0.4	0.4	0.8	-0.3	-0.7	0.6	-0.7	-0.8	-0.9	-0.9	0.6	0.6	0.4	0.5
Locomotion distance, session 8	0.6	0.9	2.2	-0.4	1.0	1.1	-1.5	-1.2	-0.9	-1.1	0.8	0.8	-0.4	-0.1
Degree of sensitization distance	0.2	0.2	0.4	-0.5	0.2	0.5	-0.6	-0.6	-0.5	-0.5	0.5	0.5	0.5	-0.2
Degree of sensitization stereotypy	0.3	0.3	1.5	0.2	0.7	0.4	-0.2	0.2	0.2	0.4	-0.5	-0.5	-1.2	-0.3
Conditioned locomotion	2.0	2.4	4.0	-1.7	-1.4	1.6	-1.2	-1.5	-1.6	-1.5	1.7	1.7	2.0	0.4
Cocaine response after cond. corrected	0.1	0.1	0.2	0.5	0.1	0.4	0.4	0.4	0.4	0.3	-0.3	-0.3	-0.2	0.5
Cocaine response after cond. not corrected	0.1	0.1	0.4	0.2	-0.2	0.5	0.3	0.2	0.2	0.1	-0.0	-0.0	0.2	0.6
Cocaine response before conditioning	0.8	0.9	1.4	-1.2	-1.0	0.8	-0.8	-1.0	-1.1	-1.0	1.0	1.0	1.2	0.1
Saline control response	0.3	0.4	1.0	-1.0	-0.2	0.4	-0.6	-0.6	-0.8	-0.6	0.6	0.6	0.2	-0.9
Bone: connectivity density	0.3	0.5	1.1	0.1	-1.1	0.2	0.9	0.8	0.3	0.8	-1.0	-1.0	-0.1	-0.9
Bone: cortical apparent density	0.1	0.1	0.7	0.1	-0.5	-0.2	0.3	0.1	0.1	0.1	-0.0	-0.0	0.1	0.8
Bone: cortical area	0.9	1.4	3.4	0.0	-0.5	1.6	-0.8	-1.2	-1.0	-1.4	1.2	1.2	1.2	1.8
Bone: cortical porosity	0.4	0.5	1.0	0.5	1.0	-0.8	0.4	0.6	0.8	0.7	-0.6	-0.6	-0.7	-0.6
Bone: cortical porosity	0.1	0.1	0.4	0.1	0.7	-0.4	-0.2	-0.1	0.1	-0.1	0.2	0.2	-0.0	0.0
Bone: cortical thickness	0.5	0.8	2.0	0.0	0.4	1.4	-1.0	-1.0	-0.7	-1.0	0.8	0.8	0.3	1.2
Bone: cortical thickness	0.2	0.2	1.0	0.7	-0.7	0.3	0.6	0.3	0.2	0.1	-0.3	-0.3	0.1	1.0
Bone: cortical tissue density	0.1	0.1	0.6	0.1	-0.5	-0.3	0.3	0.2	0.1	0.2	-0.1	-0.1	-0.0	0.7
Condit. Reinf. active minus inactive responses	1.0	1.1	2.7	0.2	-0.9	1.1	-0.7	-1.1	-1.1	-1.3	1.0	1.0	1.1	1.6
Condit. Reinf. active-inactive response ratio	0.3	0.3	1.8	0.8	-0.4	0.4	0.1	-0.2	-0.1	-0.4	0.2	0.2	0.3	1.3
Condit. Reinf. active responses	0.4	0.5	0.9	0.3	-0.3	0.9	-0.6	-0.8	-0.8	-1.0	0.6	0.6	0.6	0.9
Condit. Reinf. inactive responses	0.2	0.3	1.1	0.1	1.0	-0.2	0.0	0.3	0.3	0.4	-0.5	-0.5	-0.6	-1.0
Incentive salience index mean	0.9	1.1	2.1	0.1	-0.5	1.2	-0.9	-1.2	-1.0	-1.4	1.1	1.1	1.0	1.4
Condit. Reinf. lever presses	0.1	0.1	0.5	0.2	0.7	0.5	-0.4	-0.3	-0.1	-0.3	0.1	0.1	-0.1	-0.2
Condit. Reinf. active minus inactive responses	0.7	0.9	2.2	-0.4	-0.8	1.5	-0.9	-1.1	-1.1	-1.2	0.8	0.8	0.6	0.6
Condit. Reinf. active-inactive response ratio	0.2	0.3	1.0	0.2	0.0	1.0	-0.5	-0.6	-0.6	-0.7	0.2	0.2	0.0	0.5
Condit. Reinf. active responses	1.1	1.6	2.5	-1.3	-1.4	1.6	-1.2	-1.3	-1.6	-1.4	1.1	1.1	1.1	-0.3
Condit. Reinf. inactive responses	0.8	0.9	2.1	-1.4	-1.4	0.6	-0.7	-0.8	-1.0	-0.7	0.9	0.9	1.1	-0.8
Condit. Reinf. lever presses	0.1	0.2	0.3	-0.3	-0.4	0.4	-0.6	-0.5	-0.6	-0.4	0.1	0.1	-0.1	-0.5
Condit. Reinf. lever reinforcers received	1.1	1.5	2.4	-1.1	-1.3	1.6	-1.2	-1.4	-1.5	-1.4	1.1	1.1	1.0	-0.2
Conditioned reinforcement - actives	1.9	1.9	3.5	-1.4	0.1	1.6	-1.9	-1.7	-1.6	-1.6	1.5	1.5	0.5	0.4
Conditioned reinforcement - inactives	0.4	0.4	1.0	-0.8	0.4	0.6	-1.0	-0.8	-0.6	-0.6	0.6	0.6	-0.2	0.5
Conditioned locomotion	0.0	0.0	0.1	0.1	0.3	-0.2	-0.2	-0.1	-0.0	-0.1	0.0	0.0	-0.2	0.2
Patch foraging indifference point 0 sec	0.2	0.3	1.1	-0.3	1.1	-0.4	-0.2	0.2	0.3	0.4	-0.4	-0.4	-0.9	-0.9
Patch foraging indifference point AUC	3.5	4.0	6.9	-1.9	-0.4	2.2	-2.6	-2.5	-2.2	-2.3	2.3	2.3	1.4	0.3
Delay disc. indifference point, 0s delay	5.3	5.8	8.2	-1.9	-1.3	2.6	-2.5	-2.8	-2.7	-2.9	2.7	2.7	2.2	1.7
Delay disc. indifference point, 16s delay	0.8	0.8	2.8	-1.7	-1.6	0.7	-0.1	-0.2	-0.5	-0.1	0.7	0.7	1.1	-0.9
Delay disc. indifference point, 2s delay	2.5	2.8	5.0	-2.2	-1.2	1.9	-1.6	-1.7	-1.8	-1.6	1.8	1.8	1.7	-0.4
Delay disc. indifference point, 24s delay	0.7	0.7	5.5	-1.2	-0.1	0.3	-0.1	0.2	-0.0	0.4	-0.3	-0.3	-0.2	-2.3
Delay disc. indifference point, 4s delay	4.2	4.4	7.5	-2.7	-1.3	2.3	-2.1	-2.2	-2.2	-2.0	2.3	2.3	2.2	-0.1
Delay disc. indifference point, 8s delay	2.9	3.0	7.1	-2.7	-1.9	2.0	-1.2	-1.4	-1.8	-1.3	1.5	1.5	1.9	-1.2
Indifference point function ln k	1.0	1.4	2.4	1.0	1.2	-1.5	1.3	1.4	1.6	1.3	-1.0	-1.0	-1.1	0.2
Indifference point function log k	1.0	1.4	2.4	1.0	1.2	-1.5	1.3	1.4	1.6	1.3	-1.0	-1.0	-1.1	0.2
Patch foraging total patch changes 0 sec	0.2	0.3	1.2	-0.4	1.1	-0.4	-0.3	0.1	0.2	0.2	-0.2	-0.2	-0.8	-0.9
Patch foraging total patch changes 12 sec	0.6	0.8	2.0	-1.0	0.8	0.8	-1.4	-1.1	-0.8	-0.9	0.9	0.9	0.1	-0.6
Patch foraging total patch changes 18 sec	0.7	0.8	1.4	-1.1	-0.2	1.2	-1.2	-1.1	-1.1	-1.0	1.0	1.0	0.5	0.1
Patch foraging total patch changes 24 sec	0.5	0.6	1.5	-1.0	0.7	0.5	-1.2	-0.9	-0.7	-0.7	0.7	0.7	-0.1	-0.9
Patch foraging total patch changes 6 sec	0.3	0.5	1.7	-0.6	1.3	0.1	-1.0	-0.5	-0.3	-0.3	0.2	0.2	-0.4	-1.2
Patch foraging time to switch 0 sec	1.5	2.4	5.9	0.9	-1.7	-1.1	2.4	2.0	1.3	1.8	-1.6	-1.6	0.0	-1.1
Patch foraging water rate 0 sec	2.6	4.2	8.4	-1.4	1.4	1.8	-2.9	-2.6	-1.9	-2.5	2.4	2.4	0.7	1.5
Patch foraging water rate 12 sec	1.6	2.5	9.7	-0.1	3.1	0.9	-2.2	-1.8	-1.0	-1.8	1.4	1.4	-0.1	1.0
Patch foraging water rate 18 sec	0.4	0.5	4.3	0.1	2.1	-0.5	-0.6	-0.3	0.1	-0.3	0.3	0.3	-0.4	0.1
Patch foraging water rate 24 sec	1.0	1.4	6.1	1.1	2.5	-0.4	-0.7	-0.6	0.2	-0.7	0.6	0.6	-0.4	2.3
Patch foraging water rate 6 sec	2.1	3.1	5.4	-0.7	0.3	0.8	-2.0	-2.2	-1.8	-2.3	2.1	2.1	1.6	1.9
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.3	-0.2	0.4	-0.1	-0.1	0.1	0.0	0.2	-0.2	-0.2	-0.6	-0.5
Distance traveled before self-admin	0.4	0.4	1.4	1.2	0.8	-0.5	0.4	0.4	0.6	0.2	-0.2	-0.2	-0.3	1.1
Distance traveled after self-admin	0.4	0.4	1.3	0.2	1.2	0.7	-0.7	-0.6	-0.3	-0.6	0.3	0.3	-0.2	1.0
Extensor digitorum longus weight	0.1	0.5	2.7	1.1	1.2	-0.4	-0.0	-0.1	0.3	-0.3	0.2	0.2	-0.1	1.6
Bone: elastic displacement	0.6	0.7	1.6	0.8	0.0	-1.3	1.1	1.0	1.0	0.9	-0.8	-0.8	-0.4	0.4
Bone: elastic work	2.2	2.8	5.2	2.3	0.4	-2.1	2.0	1.8	1.9	1.6	-1.6	-1.6	-1.1	1.3
Bone: endosteal estimation	0.3	0.6	2.9	0.4	-1.7	0.0	0.6	-0.0	-0.2	-0.3	0.3	0.3	1.1	1.3
Bone: endosteal perimeter	0.5	0.9	3.0	-0.1	-1.7	0.6	0.0	-0.6	-0.8	-0.9	0.7	0.7	1.7	1.2
Epididymis fat weight	2.7	6.3	9.6	2.4	3.0	-2.1	1.8	2.5	2.8	2.7	-2.7	-2.7	-3.1	-1.1
Delta time in closed arm before/after self-admin	0.8	0.8	3.2	0.2	0.6	-0.7	0.5	0.8	0.7	1.0	-0.9	-0.9	-0.7	-1.8
Delta time in open arm before/after self-admin	1.9	1.8	3.1	-1.7	-0.7	1.8	-1.5	-1.5	-1.5	-1.4	1.4	1.4	1.0	-0.4
Diff in mean of infusions in LGA sessions	0.1	0.1	0.8	0.5	-0.2	-0.4	0.2	0.1	0.2	0.2	-0.0	-0.0	0.0	0.9
Delay discount exponential model param	2.9	3.1	8.7	2.9	1.7	-2.0	1.3	1.3	1.7	1.1	-1.5	-1.5	-1.8	1.9
Extinction: sum of active levers before priming	0.7	0.7	2.2	-0.5	-1.4	0.7	-0.2	-0.6	-0.8	-0.7	0.7	0.7	1.5	0.3
Active lever presses in extinction session 6	0.1	0.1	0.3	-0.3	0.5	0.1	-0.5	-0.4	-0.2	-0.3	0.4	0.4	0.1	0.0
Bone: final force	0.3	0.5	2.9	0.9	-0.2	0.7	-0.2	-0.4	-0.2	-0.6	0.3	0.3	0.2	1.7
Bone: final moment	0.4	0.7	3.4	0.6	-0.2	0.8	-0.5	-0.7	-0.5	-1.0	0.7	0.7	0.4	1.8
Food consumed during 24 hour testing period	0.1	0.1	0.1	-0.3	0.3	0.2	-0.4	-0.3	-0.2	-0.2	0.3	0.3	-0.1	0.1
Glucose	0.7	1.0	5.5	0.7	2.3	-0.1	-0.2	0.3	0.7	0.6	-0.8	-0.8	-1.6	-0.7
Heart weight	0.2	0.2	1.7	-0.0	-1.3	0.0	0.6	0.3	0.1	0.2	0.1	0.1	0.2	0.4
Delay discount hyperbolic model param	3.5	3.7	9.5	3.1	1.8	-2.2	1.5	1.5	1.9	1.3	-1.7	-1.7	-2.0	1.7
Intermittent access intake day 1-15 change	0.1	0.1	0.9	0.3	0.3	-0.2	0.2	-0.0	0.1	-0.2	0.2	0.2	0.4	0.9
Intermittent access intake escalation	0.2	0.2	1.2	0.5	-0.2	-0.5	0.6	0.3	0.3	0.1	-0.1	-0.1	0.4	1.1
Intermittent access intake escalation 2	0.1	0.1	0.2	-0.5	-0.3	0.1	-0.1	-0.2	-0.3	-0.2	0.3	0.3	0.3	-0.0
Intermitt. access day 1 inactive lever presses	0.9	1.0	2.3	1.5	0.4	-1.0	1.1	0.9	1.1	0.7	-0.7	-0.7	-0.2	1.5
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.5	0.7	0.5	-0.5	0.4	0.4	0.6	0.4	-0.4	-0.4	-0.1	0.4
Intermitt. access escalation Index	0.2	0.1	0.7	0.4	0.8	-0.1	-0.3	-0.2	0.1	-0.3	0.2	0.2	-0.2	0.6
Intermittent access day 1 total infusions	1.4	1.7	4.1	0.2	1.1	-1.1	0.6	1.1	1.1	1.4	-1.4	-1.4	-2.0	-1.7
Intermittent access day 15 total infusions	1.0	1.1	1.6	0.8	0.7	-1.3	1.1	1.2	1.1	1.2	-1.1	-1.1	-1.2	-0.3
Intermittent access terminal intake (last 3 days)	1.0	1.1	2.1	0.3	0.7	-1.1	0.8	1.1	1.0	1.2	-1.2	-1.2	-1.5	-1.1
Intermittent access total infusions	1.0	1.2	3.8	-0.2	0.8	-0.8	0.4	0.9	0.8	1.1	-1.1	-1.1	-1.5	-2.0
Intermittent access day 1 locomotion	0.9	1.0	1.5	0.7	0.7	-1.0	0.8	1.0	1.1	1.1	-1.2	-1.2	-1.2	-0.7
Intermittent access day 15 total locomotion	0.2	0.2	0.4	-0.1	-0.5	-0.4	0.6	0.6	0.4	0.6	-0.5	-0.5	0.1	-0.6
Intermittent access total locomotion	0.4	0.5	2.8	-0.4	-0.5	-0.3	0.5	0.6	0.2	0.6	-0.7	-0.7	-0.2	-1.7
Intermittent access standard deviation	0.6	0.7	1.1	0.0	-0.6	-0.8	0.9	1.0	0.6	1.0	-0.9	-0.9	-0.6	-1.0
Left kidney weight	0.1	0.3	1.2	-0.6	1.1	0.0	-0.4	-0.0	0.1	0.2	0.1	0.1	-0.8	-0.8
Right kidney weight	0.3	0.8	1.7	-1.2	1.1	1.0	-1.3	-0.9	-0.7	-0.7	0.9	0.9	-0.2	-0.2
Cocaine induced anxiety	0.1	0.2	0.3	0.4	-0.2	-0.2	0.4	0.4	0.4	0.4	-0.5	-0.5	-0.3	0.5
Post-drug Anxiety	2.0	2.2	4.4	1.7	-0.8	-1.4	2.1	1.8	1.5	1.6	-1.6	-1.6	-0.9	0.9
Baseline Anxiety	0.9	1.0	2.6	0.9	-1.0	-1.2	1.6	1.3	0.9	1.0	-0.8	-0.8	-0.3	0.2
Tail length	1.2	3.7	7.8	1.6	2.6	-1.5	1.1	1.7	2.1	1.9	-1.9	-1.9	-2.8	-1.3
Length with tail	0.9	3.2	4.5	2.0	0.8	-1.6	2.1	2.1	2.1	2.0	-2.0	-2.0	-1.7	0.3
Length without tail	0.6	1.2	3.9	1.2	-1.5	-0.8	1.7	0.9	0.6	0.5	-0.5	-0.5	0.5	2.0
Times rat made contact with spout	1.0	1.2	3.8	0.2	1.1	-0.8	0.4	0.9	0.8	1.1	-1.2	-1.2	-1.4	-2.0
Lifetime Intake	0.5	0.5	2.3	-0.4	0.4	-0.6	0.2	0.5	0.4	0.7	-0.6	-0.6	-1.0	-1.5
Liver weight, left	0.3	0.4	0.7	-0.6	0.3	0.6	-0.8	-0.7	-0.6	-0.8	0.9	0.9	0.5	0.1
Liver weight, right	0.4	0.7	2.5	1.6	0.5	-0.3	0.7	0.6	0.8	0.4	-0.6	-0.6	-0.6	1.5
Locomotor activity	2.2	3.5	5.7	2.3	1.1	-2.4	1.9	1.9	2.1	1.9	-2.0	-2.0	-1.7	0.7
Locomotor testing distance	1.5	2.6	4.8	2.2	1.0	-2.1	1.6	1.5	1.7	1.4	-1.6	-1.6	-1.3	1.1
Locomotor testing rearing	0.7	1.1	6.4	1.6	1.5	-0.3	-0.3	-0.3	0.3	-0.5	0.3	0.3	-0.2	2.5
Locomotion in novel chamber	1.5	1.9	5.5	-2.0	-0.3	1.6	-1.6	-1.2	-1.4	-0.9	0.9	0.9	0.3	-2.3
Locomotion in novel chamber post-restriction	2.1	2.5	5.0	-2.2	-1.3	1.7	-1.5	-1.6	-1.9	-1.5	1.7	1.7	1.1	-0.4
Fecal boli incidents, locomotor time 1	1.4	1.5	2.2	-1.0	-0.4	1.2	-1.4	-1.4	-1.3	-1.5	1.5	1.5	0.9	0.8
Change in fecal boli incidents, locomotor task	0.2	0.2	1.2	-0.7	-0.2	0.1	-0.1	0.0	-0.2	0.2	0.1	0.1	0.4	-1.1
Time >=10cm from walls, locomotor time 1	0.4	0.4	0.7	-0.4	0.0	0.2	-0.7	-0.7	-0.6	-0.8	0.8	0.8	0.6	0.4
Bouts of movement, locomotor time 1	0.6	0.6	2.1	-1.1	0.7	0.9	-1.0	-0.7	-0.6	-0.6	0.4	0.4	0.0	-1.4
Total resting periods, locomotor time 1	0.3	0.4	0.7	-0.6	0.7	0.7	-0.8	-0.6	-0.5	-0.6	0.4	0.4	-0.1	-0.7
Rest time, locomotor task time 1	2.8	3.1	5.8	-2.0	-0.7	2.4	-2.2	-2.0	-2.0	-1.8	1.7	1.7	1.2	-0.2
Distance moved, locomotor task time 1	0.4	0.4	1.2	0.9	1.1	-1.0	0.5	0.5	0.7	0.3	-0.4	-0.4	-0.3	0.5
Vertical activity count, locomotor time 1	1.0	1.0	2.5	1.0	0.7	-1.6	1.3	1.2	1.2	1.1	-0.9	-0.9	-0.5	0.1
Time >=10cm from walls, locomotor time 2	0.1	0.1	1.2	0.4	0.1	-0.3	0.2	0.1	0.2	-0.0	0.2	0.2	-0.1	1.1
Bouts of movement, locomotor time 2	0.3	0.3	1.3	-0.5	0.9	0.3	-0.5	-0.2	-0.1	-0.0	-0.1	-0.1	-0.6	-1.1
Total resting periods, locomotor time 2	0.3	0.3	1.5	-0.5	0.8	0.1	-0.3	0.0	0.0	0.2	-0.3	-0.3	-0.7	-1.2
Rest time, locomotor task time 2	0.9	1.0	2.9	-1.6	-0.8	1.3	-1.0	-0.8	-1.0	-0.5	0.4	0.4	0.2	-1.7
Distance moved, locomotor task time 2	0.3	0.4	2.9	0.7	0.4	-0.1	0.0	-0.3	-0.1	-0.5	0.3	0.3	0.4	1.7
Vertical activity count, locomotor time 2	0.4	0.4	2.9	0.5	-0.8	-0.3	0.4	0.0	-0.1	-0.2	0.3	0.3	0.7	1.7
Light reinforcement 1	0.1	0.2	1.2	0.2	1.1	-0.6	-0.2	-0.1	0.1	-0.1	0.0	0.0	-0.3	-0.1
Light reinforcement 2	0.5	0.7	1.0	1.0	1.0	-1.0	0.7	0.7	0.7	0.6	-0.9	-0.9	-0.8	-0.2
Bone: marrow area	0.3	0.6	3.2	0.4	-1.8	-0.0	0.6	0.0	-0.3	-0.3	0.3	0.3	1.1	1.3
Bone: maximum diameter	1.6	2.9	4.9	-1.0	-1.3	2.0	-1.3	-1.8	-1.8	-2.0	1.8	1.8	2.2	1.2
Bone: maximum force	0.4	0.6	2.8	1.6	-0.2	-0.3	0.7	0.4	0.5	0.2	-0.4	-0.4	-0.2	1.7
Bone: maximum moment	0.3	0.5	3.2	1.3	-0.2	-0.2	0.5	0.1	0.3	-0.1	-0.1	-0.1	-0.0	1.8
Mean time between licks in bursts	0.3	0.4	1.9	0.1	-1.4	0.1	0.9	0.6	0.2	0.5	-0.4	-0.4	0.5	-0.2
Mean num. licks in bursts	0.6	0.8	2.4	-1.6	-0.2	-0.1	-1.1	-0.9	-0.9	-0.7	0.9	0.9	0.4	-0.9
Cd content in liver	1.3	1.4	3.3	-0.9	-1.6	1.2	-0.5	-0.9	-1.1	-1.1	1.2	1.2	1.8	1.2
Co content in liver	0.1	0.2	0.5	0.3	0.6	-0.6	0.2	0.3	0.5	0.4	-0.3	-0.3	-0.7	0.1
Cu content in liver	0.9	1.0	2.1	-1.0	-0.8	1.0	-0.7	-0.9	-1.0	-1.0	1.2	1.2	1.4	0.5
Fe content in liver	0.2	0.2	2.0	-0.6	0.1	0.2	-0.3	-0.0	-0.1	0.1	-0.1	-0.1	-0.2	-1.4
K content in liver	3.5	3.5	6.0	1.8	-0.2	-2.1	2.4	2.3	2.0	2.1	-2.1	-2.1	-1.3	-0.3
Mg content in liver	0.3	0.3	0.6	0.2	-0.2	-0.8	0.7	0.7	0.6	0.7	-0.6	-0.6	-0.4	-0.4
Mn content in liver	0.1	0.2	0.6	0.0	0.4	-0.5	0.1	0.3	0.3	0.4	-0.4	-0.4	-0.8	-0.4
Na content in liver	0.1	0.1	0.7	0.4	0.8	-0.6	0.1	0.2	0.3	0.1	-0.2	-0.2	-0.3	-0.0
Rb content in liver	0.5	0.7	4.6	-0.5	-2.1	-0.2	1.0	0.6	0.0	0.4	-0.1	-0.1	0.9	-0.2
Se content in liver	1.3	1.7	3.4	-1.8	-0.3	1.6	-1.5	-1.3	-1.4	-1.1	1.2	1.2	1.0	-1.2
Sr content in liver	0.6	0.6	3.7	0.5	0.0	0.1	-0.1	-0.4	-0.2	-0.6	0.6	0.6	0.8	1.9
Zn content in liver	3.8	4.2	5.7	-2.3	-1.5	2.1	-2.0	-2.2	-2.3	-2.2	2.4	2.4	2.1	0.5
Bone: minimum diameter	0.5	1.0	2.6	0.2	-1.6	1.0	-0.0	-0.6	-0.7	-0.9	0.7	0.7	1.4	1.6
Time in familiar zone, hab. session 1	0.6	0.6	3.5	-0.6	1.9	-0.1	-0.7	-0.2	0.1	0.1	0.1	0.1	-0.8	-1.2
Time in novel zone, hab. session 1	0.7	0.6	2.6	0.3	-1.6	0.1	0.2	-0.3	-0.4	-0.5	0.4	0.4	1.0	1.6
Total zone transitions, hab. session 1	0.3	0.4	1.3	0.0	1.1	0.6	-1.0	-0.7	-0.5	-0.7	0.4	0.4	-0.3	0.0
Total locomotion distance, hab. session 1	0.5	0.7	2.2	0.1	1.5	0.6	-1.3	-1.0	-0.6	-1.0	0.8	0.8	-0.0	0.5
Locomotion velocity, hab. session 1	0.5	0.7	1.7	0.2	1.3	0.8	-1.1	-1.0	-0.6	-1.1	0.8	0.8	0.1	0.7
Time in familiar zone, hab. session 2	2.2	2.3	3.6	0.9	0.3	-1.7	1.7	1.8	1.7	1.9	-1.7	-1.7	-1.3	-0.9
Time in novel zone, hab. session 2	2.5	2.5	4.0	-0.8	0.2	1.8	-1.9	-1.9	-1.6	-2.0	1.8	1.8	1.0	1.0
Total zone transitions, hab. session 2	0.4	0.5	1.1	1.1	0.6	0.1	0.5	0.5	0.5	0.5	-0.9	-0.9	-1.0	0.1
Total locomotion distance, hab. session 2	0.2	0.3	1.5	0.7	1.2	-0.2	0.0	0.2	0.4	0.3	-0.5	-0.5	-0.8	-0.1
Locomotion velocity, hab. session 2	0.2	0.3	0.8	0.6	0.9	-0.3	0.3	0.4	0.4	0.5	-0.7	-0.7	-0.7	-0.3
Novel to familiar place preference ratio	0.1	0.1	0.2	0.2	0.4	-0.3	0.2	0.3	0.3	0.3	-0.3	-0.3	-0.4	0.0
Novelty place preference	0.2	0.2	0.4	0.4	0.5	-0.5	0.4	0.4	0.5	0.4	-0.4	-0.4	-0.6	0.1
Time in novel zone, NPP test	0.1	0.1	0.4	0.2	0.6	-0.3	0.1	0.2	0.3	0.2	-0.2	-0.2	-0.5	-0.1
Total zone transitions, NPP test	0.2	0.3	1.1	0.2	1.0	0.4	-0.6	-0.3	-0.2	-0.2	-0.2	-0.2	-0.9	-0.5
Total locomotion distance, NPP test	0.2	0.3	1.4	0.4	1.2	0.5	-0.7	-0.4	-0.2	-0.4	-0.1	-0.1	-0.7	-0.0
Locomotion velocity, NPP test	0.3	0.4	1.5	1.2	1.1	-0.1	0.1	0.2	0.4	0.2	-0.7	-0.7	-1.0	0.4
Intraocular pressure	0.2	0.3	2.0	0.7	0.0	-0.3	0.2	0.1	0.2	-0.1	0.3	0.3	0.1	1.4
Delta distance traveled before/after self-admin	0.2	0.2	0.8	-0.3	0.9	0.5	-0.6	-0.4	-0.3	-0.3	-0.0	-0.0	-0.4	0.1
Delta ambulatory time before/after self-admin	0.1	0.1	0.5	-0.1	0.7	0.3	-0.2	-0.2	-0.1	-0.1	-0.2	-0.2	-0.4	0.4
Parametrial fat weight	1.2	2.4	11.3	1.6	3.4	-0.6	-0.0	0.7	1.4	0.8	-1.2	-1.2	-2.5	-0.1
Pavlov. Cond. lever latency	0.4	0.5	0.9	0.6	-0.6	-0.7	1.0	0.8	0.7	0.7	-0.6	-0.6	-0.3	0.5
Pavlov. Cond. magazine entry latency	1.4	1.7	2.7	-1.0	0.2	1.2	-1.6	-1.6	-1.4	-1.6	1.6	1.6	1.2	0.7
Pavlov. Cond. change in total contacts	0.8	0.8	1.5	-0.6	0.6	1.0	-1.2	-1.1	-0.9	-1.1	1.0	1.0	0.6	0.1
Pavlov. Cond. index score	0.9	1.1	2.1	-0.8	0.6	1.0	-1.5	-1.4	-1.1	-1.3	1.2	1.2	0.7	0.3
Pavlov. Cond. latency score	1.1	1.4	2.1	-0.9	0.2	1.2	-1.5	-1.5	-1.3	-1.4	1.4	1.4	1.0	0.3
Pavlov. Cond. lever contacts	0.2	0.2	0.8	-0.2	0.9	0.4	-0.7	-0.5	-0.3	-0.4	0.4	0.4	0.0	-0.4
Pavlov. Cond. magazine entry number	1.1	1.4	2.3	0.7	-0.5	-1.1	1.5	1.5	1.2	1.5	-1.4	-1.4	-0.9	-0.6
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.6	0.0	0.2	-0.6	0.3	0.5	0.4	0.5	-0.4	-0.4	-0.5	-0.8
Pavlov. Cond. lever-magazine prob. diff.	1.0	1.2	2.1	-0.7	0.6	1.1	-1.5	-1.4	-1.1	-1.4	1.3	1.3	0.8	0.4
Pavlov. Cond. response bias	0.4	0.4	1.2	-0.3	1.1	0.6	-1.0	-0.8	-0.5	-0.7	0.6	0.6	0.2	-0.1
Pavlov. Cond. lever latency	0.1	0.1	0.6	-0.7	-0.1	0.2	-0.0	0.0	0.0	0.1	0.3	0.3	0.4	-0.3
Pavlov. Cond. magazine entry latency	0.2	0.2	0.7	0.8	0.2	0.5	-0.3	-0.4	-0.2	-0.4	0.0	0.0	-0.1	0.8
Pavlov. Cond. change in total contacts	0.2	0.3	1.0	1.0	0.4	-0.3	0.3	0.4	0.5	0.4	-0.7	-0.7	-0.8	0.0
Pavlov. Cond. index score	0.1	0.1	0.7	0.9	0.6	-0.0	-0.2	-0.2	0.0	-0.2	-0.3	-0.3	-0.5	0.2
Pavlov. Cond. latency score	0.1	0.2	0.8	0.9	0.6	-0.0	-0.2	-0.1	0.1	-0.1	-0.3	-0.3	-0.5	0.2
Pavlov. Cond. lever contacts	0.2	0.3	0.9	1.0	0.3	-0.5	0.3	0.3	0.3	0.3	-0.6	-0.6	-0.7	0.0
Pavlov. Cond. magazine entry number	0.1	0.1	0.5	-0.7	0.0	-0.2	0.1	0.1	0.1	0.2	0.1	0.1	0.2	-0.7
Pavlov. Cond. intertrial magazine entries	0.3	0.4	0.9	-0.1	0.5	-0.9	0.6	0.7	0.7	0.8	-0.6	-0.6	-0.6	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.9	0.9	0.7	-0.3	-0.1	0.1	0.2	0.1	-0.5	-0.5	-0.8	-0.0
Pavlov. Cond. response bias	0.1	0.1	0.5	0.7	-0.4	-0.1	0.3	0.2	0.0	0.1	-0.4	-0.4	-0.2	0.1
Time in closed arm before self-admin	0.5	0.6	2.2	1.1	-0.3	-0.6	0.8	0.6	0.6	0.5	-0.6	-0.6	-0.6	1.5
Time in closed arm after self-admin	1.0	1.0	1.8	1.4	1.2	-0.9	0.5	0.7	1.0	0.8	-1.0	-1.0	-1.3	0.7
Time in open arm before self-admin	0.1	0.1	0.7	-0.0	0.8	-0.3	-0.3	-0.2	-0.0	-0.1	0.2	0.2	0.1	-0.5
Time in open arm after self-admin	1.0	1.1	1.8	-1.3	-0.4	1.1	-1.1	-1.1	-1.2	-1.1	1.2	1.2	1.0	-0.5
Bone: periosteal estimation	0.8	1.7	4.2	0.0	-1.5	1.3	-0.5	-1.1	-1.1	-1.4	1.2	1.2	1.7	2.1
Bone: periosteal perimeter	0.3	0.6	3.4	0.7	-0.7	0.5	0.1	-0.4	-0.3	-0.7	0.4	0.4	0.8	1.8
Bone: post-yield work	0.4	0.6	1.5	1.2	0.3	-1.0	0.9	0.7	0.8	0.6	-0.7	-0.7	-0.5	0.7
Progressive ratio test 1 active lever presses	2.0	2.1	3.3	1.5	1.2	-1.8	1.2	1.4	1.6	1.5	-1.5	-1.5	-1.8	0.2
Progressive ratio test 1 breakpoint	2.0	2.1	3.6	1.5	1.0	-1.9	1.3	1.5	1.6	1.4	-1.5	-1.5	-1.6	0.4
Progressive ratio test 1 inactive lever presses	0.8	0.8	1.4	1.1	0.9	-1.2	0.7	0.8	1.1	0.8	-0.7	-0.7	-1.0	1.0
Progressive ratio test 2 active lever presses	0.6	0.6	3.0	0.4	1.7	-0.7	0.0	0.3	0.6	0.5	-0.5	-0.5	-1.4	0.1
Progressive ratio test 2 breakpoint	0.7	0.8	4.2	0.4	2.1	-0.8	-0.0	0.4	0.7	0.5	-0.5	-0.5	-1.5	-0.0
Progressive ratio test 2 inactive lever presses	0.3	0.3	0.9	-0.9	0.9	0.1	-0.8	-0.4	-0.2	-0.1	0.1	0.1	-0.7	-0.8
Incentive Sensitization - Responses	0.6	0.6	4.4	-0.5	2.1	0.1	-0.9	-0.4	-0.0	-0.2	0.2	0.2	-0.9	-0.4
Incentive Sensitization - Breakpoint	0.6	0.6	3.8	-0.6	1.9	0.3	-1.0	-0.5	-0.1	-0.3	0.3	0.3	-0.8	-0.5
Sum of active levers in priming session hrs 5-6	4.1	4.0	7.7	-2.8	-2.3	2.1	-1.4	-1.6	-2.1	-1.6	1.9	1.9	2.5	-1.4
Progressive ratio	1.1	1.3	2.8	1.5	-1.2	-1.3	1.7	1.1	1.0	0.8	-0.7	-0.7	0.2	1.5
Food seeking constrained by brief footshock	0.9	1.1	4.5	1.5	-0.5	-0.9	1.3	0.8	0.8	0.5	-0.7	-0.7	0.2	2.1
Seeking ratio, punishment vs. effort	0.3	0.3	0.6	-0.5	0.6	0.7	-0.8	-0.7	-0.6	-0.7	0.5	0.5	0.2	0.3
Retroperitoneal fat weight	0.2	0.7	5.0	0.8	2.2	0.2	-0.6	-0.2	0.4	-0.2	0.1	0.1	-0.8	0.5
Reaction time number correct	3.9	5.6	8.1	-2.8	-0.2	2.6	-2.9	-2.8	-2.6	-2.7	2.6	2.6	1.9	-0.1
Reaction time mean minus median	0.8	1.1	2.8	1.4	-0.7	-1.7	1.2	1.0	0.9	0.8	-0.8	-0.8	-0.5	1.0
Reaction time mean minus median AUC	0.9	1.2	2.3	1.5	-1.1	-1.4	1.3	1.0	0.9	0.8	-0.8	-0.8	-0.4	1.4
Reaction time num false alarms	0.5	0.6	3.2	-1.4	-0.0	0.5	-0.8	-0.5	-0.6	-0.2	0.3	0.3	-0.1	-1.8
Reaction time num false alarms AUC	0.5	0.6	3.2	-1.5	-0.0	0.3	-0.8	-0.4	-0.6	-0.2	0.3	0.3	-0.1	-1.8
Reaction time trials correct on left	3.9	5.6	8.1	-2.8	-0.2	2.6	-2.9	-2.8	-2.6	-2.7	2.6	2.6	1.9	-0.1
Reaction time trials on left	3.7	5.3	7.9	-2.7	-0.2	2.5	-2.8	-2.7	-2.6	-2.6	2.5	2.5	1.8	-0.2
Reaction time mean	4.2	5.9	8.9	2.8	0.4	-3.0	2.7	2.7	2.6	2.6	-2.7	-2.7	-2.3	0.1
Reaction time mean AUC	3.9	5.2	8.5	2.7	0.3	-2.9	2.5	2.5	2.4	2.4	-2.5	-2.5	-2.2	0.4
Median of all reaction times	4.6	6.3	8.4	2.7	0.9	-2.9	2.7	2.8	2.8	2.8	-2.8	-2.8	-2.6	-0.3
Reaction time omissions	1.1	1.5	2.6	0.9	1.2	-1.5	0.8	1.1	1.2	1.3	-1.3	-1.3	-1.6	-0.9
Reaction time false alarm rate	0.5	0.7	2.0	0.0	-0.0	-0.8	0.7	0.9	0.7	1.0	-0.9	-0.9	-0.9	-1.4
Reaction time premature initiation rate	0.0	0.1	0.2	0.4	-0.2	0.2	0.3	0.1	0.2	0.1	-0.1	-0.1	0.4	0.2
Reaction time premature initiations	0.7	1.0	1.7	-0.8	-0.1	1.3	-1.0	-1.1	-1.0	-1.1	1.1	1.1	1.2	0.3
Std. dev. reaction times	2.8	4.0	6.2	2.5	-0.2	-2.5	2.2	2.2	2.1	2.1	-2.1	-2.1	-1.8	0.7
Reaction time trials completed	3.7	5.3	7.9	-2.7	-0.2	2.5	-2.8	-2.7	-2.6	-2.6	2.5	2.5	1.8	-0.2
Reaction time trials AUC	3.7	5.3	8.1	-2.6	0.0	2.5	-2.8	-2.7	-2.5	-2.6	2.5	2.5	1.7	-0.0
Run reversals in cocaine runway, females	0.8	0.7	6.4	0.8	-0.5	-0.3	0.3	-0.2	-0.1	-0.4	0.3	0.3	0.6	2.5
Run reversals in cocaine runway, males	0.3	0.3	0.7	0.0	0.5	0.0	-0.6	-0.5	-0.3	-0.6	0.6	0.6	0.1	0.9
Latency to leave start box in cocaine runway	2.3	2.5	10.9	2.6	1.1	-1.8	1.2	0.9	1.4	0.4	-0.4	-0.4	-0.7	3.3
Latency to leave start box in cocaine runway, F	1.2	1.4	8.0	2.0	0.1	-1.1	0.9	0.5	0.7	0.0	-0.1	-0.1	-0.1	2.8
Latency to leave start box in cocaine runway, M	1.1	1.0	3.7	1.4	1.9	-1.1	0.3	0.4	0.9	0.3	-0.2	-0.2	-0.9	1.6
Std. dev. time between licks in bursts	0.6	0.7	1.8	-0.6	-1.3	0.7	-0.2	-0.6	-0.8	-0.7	0.8	0.8	1.3	0.5
Total sessions with >9 infusions	0.0	0.0	0.2	-0.0	0.1	-0.4	-0.2	-0.1	0.0	-0.1	0.2	0.2	-0.1	0.0
Short access day 1 total inactive lever presses	0.6	0.6	1.1	-0.9	-0.1	0.8	-1.0	-1.0	-0.8	-0.9	0.9	0.9	0.4	0.3
Short access day 10 total inactive lever presses	0.4	0.4	0.8	-0.4	-0.2	0.8	-0.7	-0.7	-0.6	-0.7	0.7	0.7	0.9	0.5
Short access day 1 total infusions	0.3	0.3	0.8	-0.6	0.3	0.4	-0.9	-0.7	-0.6	-0.6	0.7	0.7	-0.0	0.0
Short access day 10 total infusions	1.1	1.2	2.3	0.2	0.4	-1.1	0.8	1.1	1.0	1.3	-1.3	-1.3	-1.4	-1.5
Short access total infusions	0.2	0.2	0.8	-0.2	0.0	-0.5	0.1	0.3	0.2	0.4	-0.3	-0.3	-0.6	-0.9
Short access day 1 locomotion	0.4	0.5	1.2	0.0	-1.1	0.0	-0.1	-0.4	-0.5	-0.7	0.6	0.6	1.1	1.0
Short access day 10 total locomotion	0.2	0.2	0.6	-0.2	-0.8	-0.0	0.5	0.4	0.1	0.4	-0.5	-0.5	0.1	-0.6
Short access total locomotion	0.4	0.4	1.2	-0.5	-1.1	0.4	-0.2	-0.4	-0.5	-0.5	0.5	0.5	1.1	0.3
One hour access (0.3 mA shock)	1.2	1.4	2.8	-1.7	0.2	0.9	-1.6	-1.3	-1.3	-1.2	1.3	1.3	0.5	-1.1
Compulsive drug intake	1.0	1.0	1.7	-0.5	-0.6	0.8	-0.7	-1.0	-1.0	-1.2	1.3	1.3	1.3	0.9
One hour access (shock baseline)	0.8	0.9	2.6	-0.1	1.6	-0.7	-0.0	0.5	0.6	0.8	-0.8	-0.8	-1.6	-1.3
Social response proportion	0.6	0.6	2.0	-0.3	-0.4	-0.8	0.6	0.8	0.5	0.8	-0.8	-0.8	-0.9	-1.4
Social responses	0.5	0.6	1.7	0.0	-0.6	-1.3	0.9	0.9	0.6	0.9	-0.7	-0.7	-0.5	-1.0
Social time	3.0	3.9	5.7	-2.3	-0.5	1.7	-2.4	-2.3	-2.2	-2.2	2.4	2.4	1.6	-0.6
Soleus weight	0.1	0.3	2.1	0.9	0.5	0.1	-0.0	-0.2	0.0	-0.4	0.1	0.1	0.2	1.5
Bone: stiffness	0.0	0.0	0.2	0.4	0.2	0.1	-0.1	-0.1	-0.0	-0.1	-0.0	-0.0	-0.2	0.3
Tibialis anterior weight	0.1	0.5	1.1	0.2	1.1	0.8	-1.0	-0.9	-0.5	-0.8	0.6	0.6	-0.2	0.6
Time to tail flick, vehicle, before self-admin	0.0	0.1	0.3	0.2	-0.4	-0.2	0.1	0.0	0.0	0.1	-0.1	-0.1	-0.1	0.5
Time to tail flick, vehicle, after self-admin	0.5	0.5	2.6	0.1	-1.6	-0.2	0.8	0.7	0.3	0.7	-0.8	-0.8	-0.5	0.1
Time to tail flick, test, before self-admin	6.8	6.6	9.1	-3.0	-1.9	2.7	-2.4	-2.7	-2.9	-2.7	2.8	2.8	2.8	-0.4
Time to tail flick, test, after self-admin	1.0	1.0	2.6	-0.1	-0.6	1.2	-1.0	-1.2	-1.0	-1.2	1.0	1.0	0.6	1.6
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	1.1	-0.6	-1.1	0.5	-0.1	-0.1	-0.4	-0.0	-0.0	-0.0	0.2	-0.5
Delta time to tail flick, test, before/after SA	3.6	3.2	6.3	2.2	1.6	-1.5	1.4	1.7	1.9	1.8	-2.0	-2.0	-2.5	0.3
Tibia length	1.1	3.1	6.2	-1.4	0.6	2.4	-2.5	-2.2	-2.0	-2.1	1.8	1.8	0.7	0.0
Ambulatory time before self-admin	0.2	0.2	0.9	0.6	1.0	-0.1	-0.2	-0.1	0.3	-0.1	0.2	0.2	-0.3	0.7
Ambulatory time after self-admin	0.6	0.6	2.6	0.7	1.5	0.5	-0.6	-0.6	-0.1	-0.6	0.3	0.3	-0.4	1.6
Bone: tissue strength	0.1	0.1	0.3	-0.1	0.3	-0.3	-0.1	0.1	0.1	0.2	-0.1	-0.1	-0.3	-0.6
Total heroin consumption	0.2	0.3	1.8	-0.2	0.2	-0.4	0.3	0.4	0.3	0.5	-0.4	-0.4	-0.3	-1.3
Bone: trabecular number	0.1	0.1	0.6	-0.3	-0.8	0.8	0.0	-0.1	-0.4	-0.1	-0.1	-0.1	0.2	-0.3
Bone: trabecular spacing	0.2	0.2	0.6	-0.7	0.6	0.3	-0.7	-0.3	-0.1	-0.1	0.3	0.3	-0.1	-0.8
Bone: trabecular thickness	0.5	0.6	3.1	-0.2	-1.8	0.8	0.1	-0.4	-0.8	-0.6	0.3	0.3	1.1	0.6
Bone: trabecular tissue density	5.8	8.1	12.6	-2.7	-0.3	3.1	-3.6	-3.4	-3.2	-3.3	3.3	3.3	2.2	0.6
Water consumed over 24 hours	0.5	0.6	2.6	-0.8	1.4	-0.0	-0.8	-0.2	-0.1	0.1	-0.0	-0.0	-1.0	-1.6
Number of responses in last shaping day	0.6	0.6	1.8	-0.3	1.3	0.3	-1.0	-0.9	-0.5	-0.8	0.7	0.7	-0.3	0.9