Hub : Genes

Ubr2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr9_21532586_21533230 0.03 0.03 9.0e-03 0.01 0.02 0.02 0.01 6.9e-02 6.0e-03 9.0e-03 1.9e-02
2 NAcc isoform ratio XR_010054612.1 0.04 0.03 3.6e-07 0.05 0.05 0.03 0.05 2.7e-08 1.2e-07 3.6e-05 6.0e-08
3 Brain isoform ratio XR_010054612.1 0.06 0.04 1.3e-05 0.06 0.06 0.06 0.06 1.8e-06 6.4e-06 6.2e-06 1.9e-06
4 IL isoform ratio XM_063267356.1 0.74 0.19 3.1e-05 0.22 0.17 0.21 0.2 6.8e-06 7.1e-05 7.6e-06 1.8e-05
5 Adipose isoform ratio XR_010054612.1 0.06 0.04 5.6e-08 0.06 0.06 0.06 0.06 3.3e-07 3.0e-07 8.5e-07 6.2e-07
6 PL isoform ratio XR_010054612.1 0.3 0.19 6.0e-10 0.11 0.1 0.11 0.11 5.4e-12 6.3e-11 8.0e-12 8.2e-12
7 pVTA isoform ratio XR_010054612.1 0.06 0.04 1.6e-04 0.01 0.04 0.03 0.02 5.0e-02 7.8e-04 3.8e-03 5.3e-03
8 IL alternative TSS XM_063267356.1 0.77 0.16 6.3e-03 0.08 0.06 0.15 0.09 4.9e-03 1.3e-02 2.3e-04 3.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.81.33.2-1.61.10.91.80.71.20.60.7
Area under the delay curve6.07.010.3-2.33.13.01.33.22.73.21.5
BMI with tail3.813.216.44.1-4.0-3.7-3.8-3.5-3.9-3.3-2.7
BMI without tail5.015.320.34.0-4.5-4.1-3.6-4.0-4.1-3.9-2.9
Body weight4.319.022.84.4-4.8-4.5-3.7-4.6-4.6-4.5-3.6
Weight adjusted by age0.40.71.50.7-1.2-1.0-0.7-0.8-0.5-0.8-0.3
Bone surface1.52.84.8-2.21.81.62.11.41.81.30.7
Bone volume0.81.52.7-1.71.31.11.60.91.30.80.6
Breakpoint value in progressive ratio session0.10.10.50.3-0.10.3-0.70.30.40.30.1
Number of licking bursts2.33.76.71.4-2.2-2.2-0.4-2.5-2.2-2.6-0.3
Context. condit. distance diff. score0.20.30.50.4-0.5-0.5-0.1-0.5-0.7-0.5-0.6
Locomotion velocity, session 10.80.92.61.3-0.8-0.7-1.6-0.5-0.8-0.3-0.9
Locomotion distance, session 12.43.03.51.9-1.8-1.7-1.9-1.6-1.8-1.5-1.8
Locomotion velocity, session 26.77.811.13.2-2.8-2.7-3.3-2.3-2.8-2.2-3.0
Locomotion distance, session 21.31.72.61.6-1.3-1.3-1.6-1.2-1.1-1.1-1.3
Locomotion velocity, session 30.80.92.51.3-0.7-0.8-1.6-0.4-0.6-0.3-1.2
Locomotion distance, session 30.70.71.5-0.40.91.0-0.31.20.91.2-0.2
Stereotopy head waving bouts, day 31.01.11.81.1-1.1-1.2-0.6-1.3-1.2-1.3-0.3
Stereotopy head waving duration, day 31.51.82.41.6-1.3-1.5-1.2-1.5-1.5-1.4-0.6
Locomotion velocity, session 70.30.41.40.9-0.1-0.3-1.2-0.0-0.10.1-0.8
Locomotion distance, session 70.20.21.00.7-0.0-0.2-1.00.10.10.2-0.5
Stereotopy head waving bouts, day 70.10.10.2-0.0-0.1-0.30.4-0.40.0-0.4-0.0
Stereotopy head waving duration, day 70.20.20.9-0.60.40.21.0-0.00.4-0.00.5
Locomotion velocity, session 80.70.81.41.0-0.8-0.9-1.1-0.6-0.8-0.6-1.2
Locomotion distance, session 80.91.31.61.2-1.2-1.2-1.1-1.1-1.1-1.1-1.3
Degree of sensitization distance1.21.21.91.4-1.0-1.3-1.1-1.2-1.0-1.1-0.6
Degree of sensitization stereotypy0.60.71.2-0.90.90.71.10.61.00.60.4
Conditioned locomotion1.61.93.6-0.81.51.60.11.81.41.90.7
Cocaine response after cond. corrected0.20.20.4-0.50.40.50.40.40.30.40.7
Cocaine response after cond. not corrected0.30.40.5-0.60.60.60.40.70.60.70.7
Cocaine response before conditioning0.10.10.50.4-0.1-0.1-0.70.10.10.2-0.5
Saline control response0.10.10.50.30.2-0.1-0.40.1-0.10.2-0.7
Bone: connectivity density1.42.15.6-2.11.31.22.40.81.20.61.3
Bone: cortical apparent density0.30.40.8-0.50.80.80.40.90.40.90.2
Bone: cortical area1.11.65.91.5-0.7-0.8-1.8-0.5-0.5-0.4-2.4
Bone: cortical porosity0.00.00.10.0-0.1-0.2-0.0-0.30.0-0.3-0.1
Bone: cortical porosity0.10.10.10.3-0.2-0.2-0.4-0.3-0.0-0.2-0.2
Bone: cortical thickness1.11.85.31.6-1.0-0.9-1.9-0.6-0.8-0.5-2.3
Bone: cortical thickness0.10.10.4-0.30.10.20.70.1-0.10.00.2
Bone: cortical tissue density0.30.50.8-0.50.80.80.50.90.40.90.3
Condit. Reinf. active minus inactive responses1.51.72.41.3-1.4-1.4-0.9-1.4-1.6-1.4-0.6
Condit. Reinf. active-inactive response ratio0.30.30.60.2-0.7-0.60.1-0.7-0.6-0.70.4
Condit. Reinf. active responses2.63.24.11.9-1.8-1.9-1.4-1.9-2.0-1.9-1.4
Condit. Reinf. inactive responses1.92.32.61.6-1.4-1.6-1.2-1.6-1.6-1.6-1.4
Incentive salience index mean2.42.93.92.0-1.6-1.7-1.9-1.5-1.8-1.4-1.8
Condit. Reinf. lever presses4.25.87.92.7-2.2-2.3-2.7-2.1-2.3-2.0-2.8
Condit. Reinf. active minus inactive responses0.20.20.6-0.4-0.2-0.40.7-0.40.0-0.50.7
Condit. Reinf. active-inactive response ratio0.81.01.90.2-1.1-1.30.6-1.3-0.8-1.40.7
Condit. Reinf. active responses0.00.00.1-0.20.0-0.20.3-0.20.1-0.20.2
Condit. Reinf. inactive responses0.20.30.90.20.40.3-0.70.40.30.5-0.9
Condit. Reinf. lever presses0.30.51.00.4-0.6-1.0-0.1-1.0-0.5-1.0-0.4
Condit. Reinf. lever reinforcers received0.00.00.1-0.30.1-0.10.4-0.10.2-0.10.2
Conditioned reinforcement - actives0.40.71.50.40.50.8-1.20.90.41.0-0.9
Conditioned reinforcement - inactives0.20.30.80.8-0.4-0.4-0.9-0.4-0.2-0.3-0.8
Conditioned locomotion0.30.41.00.6-0.6-0.4-0.5-0.5-1.0-0.6-0.4
Patch foraging indifference point 0 sec0.61.12.01.1-1.1-1.2-0.5-1.2-1.4-1.2-0.1
Patch foraging indifference point AUC0.81.13.41.6-0.7-0.8-1.8-0.5-0.8-0.4-0.8
Delay disc. indifference point, 0s delay1.92.15.7-1.31.31.21.01.31.21.42.4
Delay disc. indifference point, 16s delay8.59.413.6-2.83.53.61.63.73.23.71.4
Delay disc. indifference point, 2s delay2.32.63.6-1.41.71.71.01.91.31.91.6
Delay disc. indifference point, 24s delay0.60.71.0-1.00.80.80.71.00.70.90.3
Delay disc. indifference point, 4s delay2.52.65.5-0.71.91.9-0.52.21.72.30.2
Delay disc. indifference point, 8s delay3.44.06.4-1.72.42.30.72.52.12.50.8
Indifference point function ln k0.30.50.8-0.80.50.80.60.70.40.70.9
Indifference point function log k0.30.50.8-0.80.50.80.60.70.40.70.9
Patch foraging total patch changes 0 sec0.71.42.31.2-1.3-1.3-0.7-1.4-1.5-1.3-0.2
Patch foraging total patch changes 12 sec1.41.84.11.8-0.9-0.9-2.0-0.8-1.1-0.7-1.7
Patch foraging total patch changes 18 sec0.91.42.91.7-1.1-1.2-1.6-1.0-1.1-0.9-0.7
Patch foraging total patch changes 24 sec0.30.61.21.1-0.5-0.8-0.9-0.7-0.6-0.6-0.7
Patch foraging total patch changes 6 sec2.43.65.42.2-1.8-1.9-1.8-1.8-2.3-1.7-1.7
Patch foraging time to switch 0 sec2.85.89.2-3.02.52.62.82.32.32.11.2
Patch foraging water rate 0 sec2.14.411.82.9-1.8-1.8-3.4-1.3-1.4-1.0-1.8
Patch foraging water rate 12 sec3.26.79.53.1-2.5-2.7-2.9-2.5-2.3-2.3-2.2
Patch foraging water rate 18 sec1.01.52.41.5-1.1-1.2-1.5-1.1-1.2-1.0-1.0
Patch foraging water rate 24 sec1.62.33.71.8-1.6-1.5-1.9-1.4-1.3-1.3-1.0
Patch foraging water rate 6 sec0.30.41.81.0-0.3-0.5-1.3-0.10.00.0-0.6
Seeking ratio, delayed vs. immediate footshock1.51.82.6-1.61.51.51.41.41.11.30.9
Distance traveled before self-admin0.20.21.00.5-0.2-0.1-1.0-0.1-0.1-0.0-0.7
Distance traveled after self-admin1.72.12.81.7-1.7-1.6-1.4-1.5-1.4-1.4-0.6
Extensor digitorum longus weight0.10.50.80.8-0.7-0.6-0.9-0.5-0.6-0.4-0.9
Bone: elastic displacement0.30.40.6-0.70.60.60.40.70.70.70.2
Bone: elastic work0.10.10.8-0.1-0.1-0.20.1-0.10.1-0.2-0.9
Bone: endosteal estimation0.41.01.5-1.21.11.01.00.91.20.80.7
Bone: endosteal perimeter0.00.10.40.10.0-0.1-0.2-0.10.1-0.1-0.6
Epididymis fat weight2.68.811.22.7-3.3-3.0-1.9-3.3-3.3-3.3-2.5
Delta time in closed arm before/after self-admin0.40.31.9-0.70.10.01.4-0.3-0.3-0.40.2
Delta time in open arm before/after self-admin0.20.20.6-0.00.40.5-0.20.40.50.50.8
Diff in mean of infusions in LGA sessions0.60.81.61.2-0.9-0.8-1.3-0.7-0.9-0.6-0.4
Delay discount exponential model param5.96.610.02.2-3.1-2.9-1.2-3.2-2.7-3.2-1.3
Extinction: sum of active levers before priming0.10.10.70.4-0.2-0.1-0.2-0.0-0.20.10.8
Active lever presses in extinction session 60.30.30.90.9-0.6-0.3-1.0-0.2-0.7-0.1-0.0
Bone: final force0.60.93.60.9-0.6-0.7-0.8-0.7-0.6-0.7-1.9
Bone: final moment0.61.04.11.1-0.6-0.7-1.1-0.5-0.5-0.5-2.0
Food consumed during 24 hour testing period0.40.61.31.1-0.6-0.8-1.1-0.6-0.9-0.50.1
Glucose6.19.512.23.1-3.5-3.5-2.6-3.4-3.1-3.3-1.9
Heart weight0.30.41.40.8-0.5-0.3-0.8-0.3-0.5-0.2-1.2
Delay discount hyperbolic model param5.25.89.02.1-2.9-2.7-1.1-3.0-2.5-3.0-1.1
Intermittent access intake day 1-15 change0.10.10.30.4-0.3-0.2-0.5-0.1-0.4-0.1-0.6
Intermittent access intake escalation0.00.10.20.3-0.2-0.1-0.3-0.0-0.4-0.0-0.4
Intermittent access intake escalation 20.20.20.50.30.20.3-0.60.3-0.30.4-0.7
Intermitt. access day 1 inactive lever presses0.31.02.00.5-0.9-1.10.5-1.3-1.2-1.40.1
Intermitt. access day 15 inactive lever presses0.30.71.00.8-0.9-0.7-0.5-0.9-1.0-0.9-0.7
Intermitt. access escalation Index0.10.10.6-0.2-0.1-0.00.50.0-0.1-0.00.8
Intermittent access day 1 total infusions0.40.61.20.8-0.9-0.7-0.2-0.9-1.1-0.9-0.0
Intermittent access day 15 total infusions0.30.51.20.7-0.8-0.6-0.1-0.7-1.1-0.7-0.1
Intermittent access terminal intake (last 3 days)0.00.00.10.1-0.10.10.2-0.0-0.4-0.00.1
Intermittent access total infusions0.20.20.60.5-0.5-0.2-0.1-0.4-0.8-0.40.0
Intermittent access day 1 locomotion0.70.91.80.8-1.1-1.0-0.0-1.1-1.3-1.20.1
Intermittent access day 15 total locomotion0.91.63.31.3-1.4-1.1-1.1-1.2-1.8-1.3-0.9
Intermittent access total locomotion0.70.82.00.7-1.0-0.9-0.1-1.1-1.4-1.1-0.1
Intermittent access standard deviation1.12.33.4-1.81.41.61.71.51.71.40.6
Left kidney weight1.67.59.43.0-2.8-2.6-3.1-2.5-2.5-2.4-2.9
Right kidney weight1.77.813.03.4-2.7-2.6-3.6-2.3-2.5-2.1-2.8
Cocaine induced anxiety0.20.30.9-0.0-0.5-0.40.6-0.6-0.9-0.70.3
Post-drug Anxiety0.20.20.90.1-0.4-0.30.3-0.4-0.9-0.6-0.2
Baseline Anxiety0.40.50.9-0.30.80.7-0.30.90.90.9-0.4
Tail length1.35.06.51.9-2.6-2.4-1.4-2.5-2.3-2.5-2.1
Length with tail0.83.76.31.3-2.1-2.1-0.4-2.4-2.0-2.5-1.6
Length without tail0.51.72.71.1-1.1-1.4-0.5-1.5-1.3-1.5-1.6
Times rat made contact with spout4.14.77.21.9-2.4-2.6-1.0-2.7-2.5-2.7-0.3
Lifetime Intake0.10.10.2-0.10.00.30.40.1-0.20.20.4
Liver weight, left0.81.44.31.4-0.6-0.5-2.1-0.1-0.5-0.0-2.0
Liver weight, right3.25.59.62.5-2.2-2.2-2.5-2.0-2.3-1.9-3.1
Locomotor activity2.43.85.11.7-2.2-2.3-1.2-2.1-2.0-2.1-1.7
Locomotor testing distance2.03.64.81.6-2.1-2.2-0.8-2.1-2.2-2.2-1.4
Locomotor testing rearing2.14.35.92.4-2.1-2.2-2.1-2.0-2.1-1.9-1.5
Locomotion in novel chamber0.81.01.7-0.81.31.00.31.11.31.20.1
Locomotion in novel chamber post-restriction0.61.01.9-0.11.21.1-0.81.31.01.4-0.4
Fecal boli incidents, locomotor time 10.40.61.20.10.80.8-0.80.90.81.1-0.3
Change in fecal boli incidents, locomotor task0.10.10.3-0.00.10.3-0.10.40.20.40.5
Time >=10cm from walls, locomotor time 10.20.20.50.7-0.2-0.4-0.5-0.4-0.4-0.30.2
Bouts of movement, locomotor time 10.60.72.1-0.90.30.41.4-0.10.3-0.11.4
Total resting periods, locomotor time 10.40.51.5-0.4-0.2-0.21.1-0.6-0.3-0.61.2
Rest time, locomotor task time 11.01.33.0-1.01.11.11.30.90.90.91.7
Distance moved, locomotor task time 10.10.10.50.1-0.4-0.5-0.2-0.30.2-0.3-0.7
Vertical activity count, locomotor time 10.10.30.6-0.40.50.60.10.80.60.7-0.6
Time >=10cm from walls, locomotor time 20.40.62.01.1-0.8-0.5-1.4-0.6-0.5-0.5-0.6
Bouts of movement, locomotor time 20.10.20.30.3-0.4-0.5-0.2-0.5-0.2-0.5-0.5
Total resting periods, locomotor time 20.00.00.1-0.2-0.0-0.20.3-0.20.0-0.30.0
Rest time, locomotor task time 21.01.33.5-1.30.91.01.60.60.50.61.9
Distance moved, locomotor task time 20.81.01.41.0-1.2-1.2-1.0-1.1-0.4-1.1-0.9
Vertical activity count, locomotor time 20.10.20.40.10.10.2-0.50.40.60.5-0.6
Light reinforcement 11.33.14.42.1-1.9-1.8-1.9-1.7-1.8-1.6-1.4
Light reinforcement 21.42.23.81.2-1.8-1.8-0.4-1.9-1.2-1.9-0.8
Bone: marrow area0.41.01.5-1.11.11.00.90.91.20.90.5
Bone: maximum diameter0.50.92.61.2-0.5-0.5-1.6-0.3-0.4-0.2-1.6
Bone: maximum force0.10.21.2-0.10.1-0.10.2-0.10.2-0.2-1.1
Bone: maximum moment0.10.21.30.10.1-0.1-0.1-0.00.2-0.0-1.2
Mean time between licks in bursts1.43.45.4-2.31.81.82.31.51.91.41.5
Mean num. licks in bursts0.40.61.1-0.40.80.8-0.01.00.81.00.4
Cd content in liver2.02.35.6-1.41.41.41.31.31.31.32.4
Co content in liver0.30.31.2-0.50.30.30.80.10.10.11.1
Cu content in liver0.20.20.4-0.00.40.4-0.30.60.30.60.6
Fe content in liver0.10.10.40.30.1-0.1-0.40.00.10.1-0.6
K content in liver0.40.42.1-0.90.10.11.4-0.2-0.0-0.3-0.1
Mg content in liver0.30.31.1-0.40.50.50.30.40.20.4-1.1
Mn content in liver0.40.50.90.1-0.7-0.70.6-0.9-0.9-1.00.4
Na content in liver1.21.24.81.1-0.8-0.9-1.1-0.7-0.7-0.6-2.2
Rb content in liver3.44.06.0-1.72.32.50.92.42.12.4-0.1
Se content in liver0.70.81.31.1-1.0-0.9-0.9-0.9-1.1-0.8-0.2
Sr content in liver0.80.71.11.1-0.9-0.9-1.0-0.8-0.8-0.7-0.4
Zn content in liver1.31.42.5-0.81.41.60.21.51.21.60.2
Bone: minimum diameter0.30.52.10.8-0.4-0.5-0.9-0.5-0.2-0.4-1.5
Time in familiar zone, hab. session 10.90.92.71.3-0.5-0.5-1.6-0.4-0.6-0.2-1.3
Time in novel zone, hab. session 11.51.54.9-1.40.70.61.70.60.80.52.2
Total zone transitions, hab. session 13.95.46.52.5-2.6-2.3-2.3-2.4-2.4-2.3-1.8
Total locomotion distance, hab. session 14.66.58.52.9-2.5-2.5-2.9-2.3-2.5-2.2-2.3
Locomotion velocity, hab. session 14.36.18.52.8-2.4-2.3-2.9-2.2-2.4-2.1-2.5
Time in familiar zone, hab. session 22.72.84.0-1.82.01.61.91.51.91.40.9
Time in novel zone, hab. session 20.60.61.00.8-1.0-0.7-0.9-0.6-0.9-0.60.1
Total zone transitions, hab. session 22.53.15.31.3-2.1-1.9-0.6-2.2-2.1-2.3-0.7
Total locomotion distance, hab. session 22.63.44.81.7-2.0-2.1-1.2-2.2-2.0-2.2-0.9
Locomotion velocity, hab. session 22.02.74.01.5-1.8-1.9-1.0-2.0-1.8-2.0-0.9
Novel to familiar place preference ratio0.10.10.20.4-0.4-0.3-0.2-0.3-0.4-0.3-0.2
Novelty place preference0.00.00.10.2-0.1-0.1-0.2-0.0-0.1-0.0-0.3
Time in novel zone, NPP test0.00.00.00.1-0.1-0.0-0.0-0.0-0.10.00.0
Total zone transitions, NPP test6.18.89.93.0-3.1-3.1-2.5-3.1-3.1-3.1-2.7
Total locomotion distance, NPP test5.57.58.62.7-2.8-2.9-2.2-2.9-2.8-2.9-2.4
Locomotion velocity, NPP test6.18.69.52.9-3.0-3.1-2.4-3.1-3.0-3.1-3.0
Intraocular pressure1.01.45.1-1.01.00.91.20.80.90.82.2
Delta distance traveled before/after self-admin2.32.43.71.3-1.8-1.9-0.3-1.9-1.9-1.90.2
Delta ambulatory time before/after self-admin2.32.94.41.5-2.0-2.1-0.6-2.0-1.9-2.00.1
Parametrial fat weight3.88.812.02.8-3.3-3.2-1.9-3.3-3.5-3.3-1.9
Pavlov. Cond. lever latency3.64.59.1-2.51.81.82.81.41.71.23.0
Pavlov. Cond. magazine entry latency1.11.44.51.5-0.7-0.6-2.1-0.3-0.6-0.1-1.7
Pavlov. Cond. change in total contacts2.32.54.72.0-1.6-1.4-2.2-1.2-1.5-1.0-1.4
Pavlov. Cond. index score3.44.39.02.6-1.7-1.7-3.0-1.3-1.6-1.1-2.8
Pavlov. Cond. latency score2.83.68.22.3-1.4-1.4-2.9-0.9-1.3-0.7-2.8
Pavlov. Cond. lever contacts3.84.68.42.5-1.9-1.8-2.8-1.5-1.7-1.3-2.9
Pavlov. Cond. magazine entry number2.73.57.4-2.41.61.52.71.21.51.02.2
Pavlov. Cond. intertrial magazine entries0.81.01.3-1.10.91.01.11.00.80.91.0
Pavlov. Cond. lever-magazine prob. diff.3.13.88.42.5-1.6-1.6-2.9-1.2-1.4-1.0-2.6
Pavlov. Cond. response bias4.25.29.22.8-2.2-2.0-3.0-1.7-2.0-1.6-2.6
Pavlov. Cond. lever latency2.23.04.2-1.51.72.01.02.01.72.01.5
Pavlov. Cond. magazine entry latency2.12.53.11.5-1.6-1.7-1.0-1.8-1.5-1.7-1.7
Pavlov. Cond. change in total contacts1.72.84.21.4-1.6-2.0-0.7-2.0-1.6-2.1-1.4
Pavlov. Cond. index score3.64.86.22.1-2.2-2.5-1.4-2.5-2.1-2.5-2.0
Pavlov. Cond. latency score3.95.26.72.2-2.3-2.6-1.5-2.6-2.3-2.6-2.0
Pavlov. Cond. lever contacts2.43.44.61.6-1.8-2.0-1.1-2.1-1.8-2.1-1.8
Pavlov. Cond. magazine entry number0.70.92.6-0.90.80.90.60.90.60.91.6
Pavlov. Cond. intertrial magazine entries0.00.00.10.1-0.2-0.0-0.30.0-0.30.00.3
Pavlov. Cond. lever-magazine prob. diff.3.74.96.52.1-2.3-2.5-1.4-2.5-2.2-2.5-2.0
Pavlov. Cond. response bias1.01.32.40.9-1.0-1.3-0.5-1.3-1.0-1.4-1.6
Time in closed arm before self-admin0.20.20.9-0.60.30.20.90.00.1-0.10.6
Time in closed arm after self-admin0.70.73.3-0.8-0.2-0.21.8-0.6-0.5-0.80.6
Time in open arm before self-admin2.32.54.21.9-1.6-1.5-2.0-1.3-1.2-1.1-1.6
Time in open arm after self-admin0.60.62.71.2-0.5-0.5-1.6-0.3-0.1-0.1-0.5
Bone: periosteal estimation0.10.21.10.5-0.0-0.1-0.7-0.00.20.0-1.1
Bone: periosteal perimeter1.01.85.21.4-1.0-1.1-1.5-1.0-0.8-0.9-2.3
Bone: post-yield work0.10.10.4-0.30.0-0.10.6-0.3-0.1-0.4-0.0
Progressive ratio test 1 active lever presses0.70.81.40.6-1.1-1.10.2-1.2-1.1-1.20.3
Progressive ratio test 1 breakpoint0.60.71.20.6-1.0-1.00.2-1.1-1.0-1.10.3
Progressive ratio test 1 inactive lever presses0.40.51.01.0-0.6-0.9-0.5-0.9-0.7-0.8-0.3
Progressive ratio test 2 active lever presses2.02.33.11.8-1.6-1.5-1.3-1.6-1.8-1.5-0.9
Progressive ratio test 2 breakpoint2.32.63.61.9-1.7-1.6-1.5-1.7-1.9-1.6-0.9
Progressive ratio test 2 inactive lever presses0.50.91.41.1-0.9-0.7-0.8-0.9-1.2-0.9-0.7
Incentive Sensitization - Responses1.11.62.41.5-1.1-1.1-1.6-1.2-1.4-1.1-1.1
Incentive Sensitization - Breakpoint1.21.62.31.5-1.1-1.1-1.5-1.2-1.4-1.1-1.1
Sum of active levers in priming session hrs 5-60.50.52.30.9-0.10.1-1.50.50.20.7-0.0
Progressive ratio0.30.50.8-0.60.80.90.60.90.80.9-0.1
Food seeking constrained by brief footshock0.10.20.50.0-0.1-0.30.7-0.4-0.5-0.50.2
Seeking ratio, punishment vs. effort0.20.40.60.5-0.6-0.7-0.2-0.7-0.8-0.70.3
Retroperitoneal fat weight2.711.715.63.9-3.5-3.4-3.8-3.2-3.5-3.0-3.0
Reaction time number correct0.20.41.10.20.30.5-1.00.70.70.80.1
Reaction time mean minus median0.00.10.2-0.30.30.30.20.30.10.3-0.4
Reaction time mean minus median AUC0.20.51.3-1.00.70.61.10.60.60.50.6
Reaction time num false alarms0.60.81.2-0.91.01.11.00.90.70.90.7
Reaction time num false alarms AUC0.40.60.9-0.70.90.90.70.80.70.80.5
Reaction time trials correct on left0.20.41.10.20.30.5-1.00.70.70.80.1
Reaction time trials on left0.20.31.10.30.20.4-1.00.60.70.70.1
Reaction time mean0.50.84.2-1.20.40.22.1-0.00.2-0.20.8
Reaction time mean AUC0.60.94.8-1.20.30.12.2-0.10.1-0.31.0
Median of all reaction times0.71.05.0-1.20.30.02.2-0.20.2-0.31.0
Reaction time omissions0.30.50.80.5-0.7-0.7-0.4-0.7-0.9-0.7-0.8
Reaction time false alarm rate0.60.82.0-1.10.90.91.40.70.60.60.6
Reaction time premature initiation rate0.91.21.81.2-1.1-1.3-0.7-1.2-1.3-1.1-0.5
Reaction time premature initiations0.61.22.11.5-1.0-1.1-1.4-0.9-1.0-0.8-0.6
Std. dev. reaction times0.20.31.6-0.80.30.31.30.10.10.00.1
Reaction time trials completed0.20.31.10.30.20.4-1.00.60.70.70.1
Reaction time trials AUC0.20.31.20.40.10.3-1.10.40.50.60.0
Run reversals in cocaine runway, females1.21.22.51.3-0.9-1.1-1.5-0.7-0.6-0.6-1.6
Run reversals in cocaine runway, males0.00.00.10.30.1-0.1-0.1-0.1-0.0-0.10.4
Latency to leave start box in cocaine runway1.11.31.71.3-1.2-1.1-1.1-1.2-1.2-1.1-0.8
Latency to leave start box in cocaine runway, F0.10.10.20.2-0.3-0.3-0.1-0.5-0.1-0.5-0.3
Latency to leave start box in cocaine runway, M4.13.85.32.3-2.1-2.0-1.9-1.9-2.2-1.8-1.1
Std. dev. time between licks in bursts1.31.72.6-1.31.41.60.91.41.41.41.0
Total sessions with >9 infusions0.10.10.3-0.10.10.30.10.30.20.40.6
Short access day 1 total inactive lever presses0.10.10.20.5-0.4-0.4-0.4-0.40.0-0.4-0.4
Short access day 10 total inactive lever presses0.00.10.20.3-0.4-0.4-0.1-0.4-0.2-0.4-0.0
Short access day 1 total infusions0.20.30.6-0.40.40.80.20.60.70.60.5
Short access day 10 total infusions0.10.10.3-0.30.00.30.60.10.10.10.4
Short access total infusions0.81.01.5-1.00.81.21.01.00.81.01.1
Short access day 1 locomotion0.10.10.2-0.30.20.40.40.30.10.20.5
Short access day 10 total locomotion0.61.12.3-1.40.80.91.50.70.90.61.1
Short access total locomotion0.50.60.7-0.70.70.80.60.80.80.80.8
One hour access (0.3 mA shock)0.10.10.30.40.20.4-0.40.5-0.20.5-0.2
Compulsive drug intake0.10.20.3-0.10.40.3-0.00.50.50.50.3
One hour access (shock baseline)0.30.51.10.8-0.8-0.5-0.4-0.7-1.0-0.7-0.5
Social response proportion0.91.01.5-1.11.21.20.61.11.21.1-0.4
Social responses1.92.43.6-1.51.91.80.81.81.71.7-0.6
Social time1.31.73.3-0.11.41.3-1.01.61.51.8-0.9
Soleus weight0.61.83.51.5-1.3-1.1-1.5-1.0-1.1-1.0-1.9
Bone: stiffness0.10.10.3-0.20.60.20.30.10.30.1-0.4
Tibialis anterior weight0.20.60.90.8-1.0-0.9-0.6-0.9-0.7-0.9-0.6
Time to tail flick, vehicle, before self-admin0.50.61.2-0.50.90.70.10.81.10.8-0.6
Time to tail flick, vehicle, after self-admin1.92.54.5-2.11.81.52.11.51.31.30.4
Time to tail flick, test, before self-admin2.42.54.8-1.01.92.0-0.22.11.52.20.2
Time to tail flick, test, after self-admin1.01.01.4-1.11.21.00.71.21.01.20.5
Delta time to tail flick, vehicle, before/after SA0.50.51.0-1.00.70.60.90.70.60.60.3
Delta time to tail flick, test, before/after SA0.70.71.4-0.3-0.7-0.91.1-1.0-0.8-1.20.1
Tibia length2.98.110.83.3-3.0-3.0-3.2-2.6-2.5-2.5-2.5
Ambulatory time before self-admin0.20.30.80.30.30.4-0.90.50.10.5-0.6
Ambulatory time after self-admin1.92.23.11.8-1.7-1.6-1.5-1.5-1.6-1.4-0.7
Bone: tissue strength0.10.10.2-0.10.20.1-0.20.30.40.3-0.3
Total heroin consumption0.20.20.60.6-0.8-0.2-0.6-0.4-0.3-0.4-0.2
Bone: trabecular number0.71.12.0-1.41.11.01.30.91.20.80.0
Bone: trabecular spacing0.60.82.11.3-0.9-0.8-1.4-0.5-0.9-0.4-0.5
Bone: trabecular thickness1.31.73.0-1.71.31.21.71.01.30.90.9
Bone: trabecular tissue density0.30.40.80.50.40.3-0.90.70.30.80.8
Water consumed over 24 hours2.73.65.12.3-1.9-2.0-2.2-1.8-2.0-1.7-1.4
Number of responses in last shaping day0.10.10.20.3-0.2-0.1-0.4-0.1-0.2-0.0-0.3