Hub : Genes

Tymp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr7_122320252_122320332 0.02 0.02 2.6e-03 0.02 0.02 0.01 0.01 3.2e-03 1.6e-03 1.2e-02 7.9e-03
2 Liver intron excision ratio chr7_122321069_122321421 0.03 0.02 8.2e-04 0.03 0.03 0.03 0.03 1.1e-04 8.5e-04 3.3e-04 2.6e-04
3 Liver intron excision ratio chr7_122321539_122321644 0.04 0.03 7.1e-05 0.04 0.03 0.04 0.04 1.9e-05 1.3e-04 5.0e-05 4.8e-05
4 Brain mRNA stability Tymp 0.02 0.01 8.8e-03 0.02 0.01 0 0.02 2.6e-03 1.7e-02 1.4e-01 8.5e-03
5 Liver gene expression Tymp 0.32 0.1 0.0e+00 0.23 0.22 0.23 0.23 3.2e-25 2.0e-24 5.1e-25 2.2e-25
6 Liver mRNA stability Tymp 0.12 0.1 7.6e-03 0.01 0 0 0.01 2.5e-02 8.8e-02 1.3e-01 3.0e-02
7 Liver alternative TSS XM_039079311.2 0.07 0.05 1.1e-04 0.03 0.04 0.04 0.04 1.9e-04 4.0e-05 1.6e-05 7.8e-05
8 Liver alternative TSS NM_001012122.2 0.07 0.04 1.0e-04 0.02 0.04 0.04 0.04 5.6e-03 4.3e-05 2.5e-05 3.6e-05
9 Liver isoform ratio XM_039079311.2 0.11 0.07 2.5e-04 0.03 0.02 0.02 0.03 3.7e-04 1.5e-03 4.1e-03 7.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.22.03.41.71.5-1.5-1.51.1-0.51.6-1.80.7
Area under the delay curve1.11.23.60.71.0-1.0-0.71.1-1.90.6-0.11.7
BMI with tail2.79.216.4-4.1-3.93.93.6-3.91.90.81.3-1.2
BMI without tail1.85.58.2-2.9-2.72.72.4-2.82.40.11.8-1.8
Body weight1.35.610.2-3.2-2.92.93.2-2.81.60.51.3-1.1
Weight adjusted by age1.32.04.1-2.0-1.81.81.9-1.70.10.6-0.10.2
Bone surface1.52.85.51.61.6-1.6-1.41.2-1.32.0-2.41.7
Bone volume1.73.05.71.91.7-1.7-1.71.4-1.02.1-2.41.5
Breakpoint value in progressive ratio session0.10.20.6-0.4-0.30.30.8-0.2-0.20.3-0.30.4
Number of licking bursts0.00.00.20.10.1-0.1-0.1-0.0-0.00.10.1-0.5
Context. condit. distance diff. score2.02.44.4-1.8-1.61.61.6-1.62.1-0.01.3-1.3
Locomotion velocity, session 10.30.31.7-0.5-0.40.40.5-0.5-0.11.3-0.3-0.3
Locomotion distance, session 11.62.03.41.51.8-1.8-1.51.7-1.60.4-0.11.1
Locomotion velocity, session 20.50.61.2-0.8-0.90.90.6-1.10.01.0-0.2-0.4
Locomotion distance, session 20.81.12.61.01.4-1.4-0.91.1-1.60.50.00.6
Locomotion velocity, session 31.01.13.5-0.6-0.40.40.4-0.81.3-1.11.6-1.9
Locomotion distance, session 30.10.10.50.40.1-0.1-0.70.20.40.30.4-0.4
Stereotopy head waving bouts, day 32.53.04.31.91.6-1.6-1.81.6-1.51.9-2.11.4
Stereotopy head waving duration, day 30.80.91.71.21.0-1.0-1.01.0-0.61.0-1.30.4
Locomotion velocity, session 71.21.34.4-0.5-1.41.40.2-0.82.1-0.40.1-1.6
Locomotion distance, session 70.50.61.5-0.6-0.80.80.4-0.40.9-0.81.2-0.8
Stereotopy head waving bouts, day 70.91.01.81.11.4-1.4-1.00.8-0.40.4-1.30.5
Stereotopy head waving duration, day 70.80.91.71.31.2-1.2-1.30.80.10.1-1.1-0.2
Locomotion velocity, session 81.01.22.0-0.8-1.31.30.7-1.41.40.9-0.6-1.3
Locomotion distance, session 80.50.71.4-1.2-0.80.81.2-1.00.41.00.6-0.2
Degree of sensitization distance0.90.92.1-1.3-1.21.21.4-1.10.20.2-0.00.0
Degree of sensitization stereotypy0.20.20.60.20.5-0.5-0.1-0.00.6-0.8-0.2-0.6
Conditioned locomotion0.40.50.9-0.7-0.80.80.6-0.90.80.20.0-0.5
Cocaine response after cond. corrected0.91.11.8-1.2-1.21.21.1-1.31.2-0.50.5-0.8
Cocaine response after cond. not corrected2.32.74.3-1.9-1.81.81.7-2.11.8-0.71.1-1.4
Cocaine response before conditioning0.81.01.5-1.2-1.11.10.9-1.21.0-0.10.9-0.8
Saline control response0.40.60.8-0.9-0.70.70.9-0.9-0.80.7-0.10.8
Bone: connectivity density0.81.22.11.41.2-1.2-1.30.7-0.31.3-1.30.5
Bone: cortical apparent density1.52.03.41.81.8-1.8-1.81.8-1.00.5-0.70.4
Bone: cortical area0.60.92.9-0.4-0.80.80.5-0.4-0.41.7-1.40.9
Bone: cortical porosity0.60.62.5-0.5-0.40.40.7-0.4-0.81.6-0.61.0
Bone: cortical porosity0.80.91.8-1.0-0.60.61.3-0.8-0.71.3-0.51.0
Bone: cortical thickness0.20.31.10.1-0.20.2-0.00.3-0.31.1-1.00.4
Bone: cortical thickness0.70.82.4-0.5-1.21.20.3-0.31.5-0.40.6-0.8
Bone: cortical tissue density1.31.72.91.71.7-1.7-1.61.7-0.90.4-0.60.3
Condit. Reinf. active minus inactive responses1.01.12.5-0.7-1.31.30.6-1.20.51.6-1.20.1
Condit. Reinf. active-inactive response ratio0.30.31.20.0-0.40.4-0.1-0.50.41.1-0.8-0.1
Condit. Reinf. active responses1.31.63.0-1.2-1.71.71.1-1.60.81.2-0.9-0.2
Condit. Reinf. inactive responses0.91.12.0-1.3-1.41.41.3-1.40.50.10.1-0.3
Incentive salience index mean1.51.83.7-1.1-1.71.71.0-1.50.41.9-1.50.3
Condit. Reinf. lever presses1.11.62.9-1.2-1.51.51.2-1.4-0.01.7-1.10.4
Condit. Reinf. active minus inactive responses1.01.23.20.80.2-0.2-0.61.0-1.11.2-1.81.8
Condit. Reinf. active-inactive response ratio0.30.30.80.6-0.00.0-0.50.6-0.50.6-0.90.8
Condit. Reinf. active responses0.50.73.10.1-0.50.5-0.10.2-0.71.1-1.11.8
Condit. Reinf. inactive responses0.30.40.7-0.8-0.80.80.6-0.60.10.20.60.7
Condit. Reinf. lever presses0.50.71.6-0.9-1.21.20.7-0.80.00.9-0.50.6
Condit. Reinf. lever reinforcers received0.60.93.60.2-0.30.3-0.20.4-0.91.2-1.41.9
Conditioned reinforcement - actives0.20.40.7-0.7-0.80.80.8-0.70.00.6-0.50.6
Conditioned reinforcement - inactives0.20.30.5-0.5-0.60.60.7-0.60.60.4-0.2-0.3
Conditioned locomotion1.72.24.0-2.0-1.91.91.7-1.81.1-0.20.9-0.7
Patch foraging indifference point 0 sec0.20.30.7-0.7-0.80.80.6-0.60.1-0.50.0-0.2
Patch foraging indifference point AUC2.13.18.60.81.0-1.0-0.80.9-2.22.9-1.92.6
Delay disc. indifference point, 0s delay1.01.12.4-0.4-0.60.60.1-0.4-1.51.6-1.51.2
Delay disc. indifference point, 16s delay0.40.51.40.30.5-0.5-0.10.4-0.91.0-0.51.2
Delay disc. indifference point, 2s delay4.65.113.21.81.9-1.9-1.62.0-3.61.6-1.43.3
Delay disc. indifference point, 24s delay0.40.41.2-0.7-0.60.61.1-0.7-0.20.60.8-0.2
Delay disc. indifference point, 4s delay1.21.34.00.61.1-1.1-0.91.1-2.00.2-0.41.7
Delay disc. indifference point, 8s delay0.80.91.50.81.2-1.2-0.61.2-1.1-0.41.00.9
Indifference point function ln k2.03.54.2-2.0-2.02.01.5-1.82.0-2.01.5-1.9
Indifference point function log k2.03.54.2-2.0-2.02.01.5-1.82.0-2.01.5-1.9
Patch foraging total patch changes 0 sec0.10.20.3-0.4-0.50.50.5-0.40.2-0.6-0.1-0.2
Patch foraging total patch changes 12 sec1.11.44.10.30.1-0.1-0.30.1-1.42.0-1.81.7
Patch foraging total patch changes 18 sec1.72.64.61.61.3-1.3-1.51.6-1.41.9-1.62.2
Patch foraging total patch changes 24 sec0.71.23.61.10.5-0.5-1.00.8-0.61.5-1.91.2
Patch foraging total patch changes 6 sec0.50.72.10.00.6-0.60.10.2-1.31.2-0.81.4
Patch foraging time to switch 0 sec0.10.20.70.80.6-0.6-0.50.5-0.0-0.1-0.40.1
Patch foraging water rate 0 sec0.61.32.1-1.4-1.21.20.9-1.01.2-1.21.2-0.9
Patch foraging water rate 12 sec1.12.33.9-2.0-1.81.81.5-1.61.2-1.41.0-1.1
Patch foraging water rate 18 sec3.55.47.2-2.5-2.32.32.3-2.22.5-2.71.7-2.4
Patch foraging water rate 24 sec1.92.65.6-1.7-1.11.11.2-1.41.8-2.41.9-1.7
Patch foraging water rate 6 sec0.81.22.1-1.3-1.01.00.9-0.90.9-1.31.5-0.9
Seeking ratio, delayed vs. immediate footshock0.30.40.91.00.8-0.8-0.70.80.1-0.3-0.4-0.1
Distance traveled before self-admin0.81.01.81.21.3-1.3-1.31.2-0.70.4-0.50.5
Distance traveled after self-admin0.10.10.30.20.1-0.1-0.20.00.5-0.20.3-0.6
Extensor digitorum longus weight0.41.52.2-1.4-1.41.41.3-1.31.5-0.40.7-0.9
Bone: elastic displacement0.40.40.90.41.0-1.0-0.20.4-0.5-0.60.90.4
Bone: elastic work0.20.20.8-0.7-0.30.30.9-0.6-0.10.30.10.2
Bone: endosteal estimation0.10.30.4-0.6-0.50.50.5-0.6-0.20.5-0.40.6
Bone: endosteal perimeter1.02.25.9-0.3-0.70.70.3-0.5-1.32.4-2.42.2
Epididymis fat weight1.24.07.0-1.7-2.62.62.2-2.10.32.6-1.80.2
Delta time in closed arm before/after self-admin0.20.21.0-0.10.1-0.10.50.2-0.3-0.41.00.7
Delta time in open arm before/after self-admin0.10.10.70.10.0-0.0-0.4-0.0-0.10.1-0.8-0.4
Diff in mean of infusions in LGA sessions0.81.02.3-0.9-1.01.01.2-1.00.11.5-1.00.8
Delay discount exponential model param0.90.92.7-0.6-1.01.00.6-1.01.6-0.3-0.3-1.5
Extinction: sum of active levers before priming0.30.31.20.40.6-0.6-0.10.6-0.50.5-0.21.1
Active lever presses in extinction session 61.71.73.0-1.7-1.51.51.5-1.61.2-0.20.9-0.7
Bone: final force0.30.51.60.30.0-0.0-0.30.4-0.71.1-1.20.7
Bone: final moment0.20.41.10.40.3-0.3-0.40.5-0.70.9-1.00.7
Food consumed during 24 hour testing period1.62.23.5-1.8-1.91.91.8-1.81.2-0.20.8-1.0
Glucose0.20.40.90.30.6-0.6-0.40.4-0.70.9-0.50.8
Heart weight0.40.71.5-0.7-0.90.90.4-0.80.8-0.50.8-1.2
Delay discount hyperbolic model param1.31.43.7-0.8-1.21.20.9-1.21.9-0.5-0.1-1.7
Intermittent access intake day 1-15 change0.30.61.3-1.0-0.90.91.1-0.90.5-0.20.30.0
Intermittent access intake escalation0.30.61.4-1.1-1.01.01.2-1.00.5-0.10.2-0.0
Intermittent access intake escalation 21.11.22.0-1.1-1.31.31.4-1.2-0.00.9-1.30.7
Intermitt. access day 1 inactive lever presses0.10.50.9-1.0-0.80.80.9-0.80.10.7-0.40.2
Intermitt. access day 15 inactive lever presses1.83.65.1-2.1-2.02.01.9-2.12.3-1.41.1-1.7
Intermitt. access escalation Index0.30.41.00.70.5-0.5-0.70.50.4-1.00.7-0.3
Intermittent access day 1 total infusions0.20.31.6-0.2-0.20.20.2-0.20.6-0.61.3-0.5
Intermittent access day 15 total infusions0.20.40.9-0.6-0.50.50.7-0.50.7-0.50.9-0.2
Intermittent access terminal intake (last 3 days)0.81.02.4-1.3-1.21.21.6-1.10.6-0.10.60.0
Intermittent access total infusions0.20.30.9-0.5-0.50.50.6-0.40.5-0.21.0-0.1
Intermittent access day 1 locomotion0.00.00.30.00.0-0.0-0.20.00.2-0.10.60.2
Intermittent access day 15 total locomotion0.40.71.5-1.2-1.01.01.0-1.00.30.20.9-0.0
Intermittent access total locomotion0.70.91.8-1.1-0.90.90.8-1.00.9-0.61.3-0.4
Intermittent access standard deviation0.40.81.8-0.8-0.70.70.8-0.81.3-1.00.4-1.0
Left kidney weight3.114.226.2-5.0-4.74.75.1-4.92.40.21.0-1.6
Right kidney weight5.123.143.0-6.3-5.85.86.6-6.13.3-0.02.1-2.5
Cocaine induced anxiety1.01.42.5-1.2-1.21.21.6-1.10.8-1.41.0-0.9
Post-drug Anxiety1.71.82.9-1.4-1.31.31.7-1.31.3-1.51.0-1.1
Baseline Anxiety0.20.30.50.70.7-0.7-0.70.60.20.1-0.40.2
Tail length0.20.91.71.31.3-1.3-0.91.1-0.20.6-0.70.3
Length with tail0.00.20.50.00.2-0.20.60.2-0.50.4-0.70.4
Length without tail0.30.82.4-0.8-0.60.61.5-0.6-0.90.8-1.10.8
Times rat made contact with spout3.13.67.1-1.5-1.11.11.5-1.12.3-2.72.6-2.2
Lifetime Intake0.40.51.7-0.7-0.60.60.7-0.60.6-0.31.3-0.3
Liver weight, left0.30.52.1-0.7-0.30.30.3-0.2-1.21.4-0.10.8
Liver weight, right0.20.30.60.10.5-0.5-0.20.5-0.70.7-0.10.8
Locomotor activity0.40.61.3-0.4-0.20.20.1-0.4-1.01.1-1.11.1
Locomotor testing distance0.50.92.41.01.2-1.2-1.61.0-0.8-0.4-0.20.7
Locomotor testing rearing1.22.47.10.71.0-1.0-0.70.9-2.31.6-1.92.7
Locomotion in novel chamber2.32.97.8-1.6-1.41.41.4-1.52.8-1.11.1-2.3
Locomotion in novel chamber post-restriction0.20.41.50.60.2-0.2-0.60.40.10.7-0.81.2
Fecal boli incidents, locomotor time 10.30.40.70.60.8-0.8-0.70.7-0.10.40.60.1
Change in fecal boli incidents, locomotor task0.40.41.3-0.7-0.50.51.2-0.5-0.0-0.9-0.1-0.3
Time >=10cm from walls, locomotor time 10.40.41.6-0.4-0.50.50.6-0.5-0.30.8-1.30.2
Bouts of movement, locomotor time 10.50.51.7-0.3-0.80.80.9-0.61.30.3-0.3-0.7
Total resting periods, locomotor time 10.20.31.4-0.0-0.30.30.7-0.21.20.2-0.3-0.5
Rest time, locomotor task time 10.60.82.60.00.0-0.00.1-0.01.2-1.51.6-0.9
Distance moved, locomotor task time 10.20.30.8-0.2-0.40.4-0.1-0.4-0.80.7-0.90.4
Vertical activity count, locomotor time 10.30.81.7-0.8-1.01.00.1-0.8-0.81.2-1.30.4
Time >=10cm from walls, locomotor time 20.81.22.4-1.4-1.41.41.5-1.40.10.5-0.4-0.3
Bouts of movement, locomotor time 20.20.30.40.60.6-0.6-0.60.70.60.6-0.10.0
Total resting periods, locomotor time 20.20.40.60.70.6-0.6-0.70.70.50.8-0.20.2
Rest time, locomotor task time 20.60.81.10.90.8-0.8-0.50.80.8-1.01.1-0.9
Distance moved, locomotor task time 20.80.91.8-1.3-1.31.30.7-1.3-0.30.8-0.40.3
Vertical activity count, locomotor time 20.81.12.1-1.4-1.41.40.4-1.4-0.51.0-0.60.7
Light reinforcement 10.20.51.0-0.7-0.60.60.5-0.9-0.41.0-0.90.5
Light reinforcement 21.21.93.1-1.8-1.71.71.8-1.6-0.41.0-0.80.6
Bone: marrow area0.10.20.5-0.4-0.30.30.4-0.4-0.30.5-0.50.7
Bone: maximum diameter0.61.22.5-1.1-1.61.60.9-1.30.31.1-0.70.5
Bone: maximum force0.10.20.9-0.1-0.10.10.20.1-0.50.9-0.80.5
Bone: maximum moment0.10.10.50.00.2-0.20.10.2-0.40.7-0.60.4
Mean time between licks in bursts0.71.83.51.81.8-1.8-1.91.6-0.4-0.50.5-0.2
Mean num. licks in bursts0.50.82.7-0.7-0.40.40.8-0.31.0-1.61.2-0.6
Cd content in liver0.50.51.00.70.8-0.8-0.70.9-0.60.4-0.51.0
Co content in liver0.30.31.2-0.4-0.20.20.5-0.6-1.10.6-0.60.4
Cu content in liver1.11.44.30.50.2-0.2-0.80.61.3-2.11.5-1.6
Fe content in liver0.30.41.10.40.4-0.4-0.30.5-0.90.6-0.61.1
K content in liver0.30.31.00.70.3-0.3-0.70.1-0.30.8-1.00.0
Mg content in liver1.21.21.71.11.2-1.2-1.00.7-1.30.9-1.31.0
Mn content in liver0.30.41.50.40.1-0.1-0.3-0.3-0.61.0-1.20.2
Na content in liver4.65.07.82.71.9-1.9-2.82.4-1.71.8-2.42.1
Rb content in liver0.30.41.00.20.3-0.3-0.10.0-0.90.7-0.91.0
Se content in liver0.30.41.1-0.5-0.50.50.6-0.81.0-0.50.2-0.6
Sr content in liver0.80.71.41.11.0-1.0-1.21.00.0-0.60.3-0.3
Zn content in liver0.50.51.60.40.7-0.7-0.40.40.1-1.11.2-0.7
Bone: minimum diameter0.40.82.9-0.3-0.80.80.2-0.4-0.31.7-1.50.7
Time in familiar zone, hab. session 11.41.43.9-0.8-0.40.40.8-0.80.9-1.92.0-1.3
Time in novel zone, hab. session 11.71.74.41.10.8-0.8-1.10.9-0.82.1-2.01.4
Total zone transitions, hab. session 11.82.54.41.62.1-2.1-1.32.1-1.80.1-0.41.3
Total locomotion distance, hab. session 10.40.51.9-0.00.8-0.80.40.5-1.4-0.30.11.0
Locomotion velocity, hab. session 10.50.83.30.20.9-0.90.20.6-1.8-0.3-0.11.2
Time in familiar zone, hab. session 22.22.33.3-1.3-1.51.51.0-1.51.5-1.81.8-1.6
Time in novel zone, hab. session 22.32.33.41.51.7-1.7-1.21.4-1.31.8-1.81.2
Total zone transitions, hab. session 20.40.52.2-0.7-0.30.30.6-0.30.2-1.01.5-0.5
Total locomotion distance, hab. session 20.81.02.8-1.5-0.80.81.7-1.2-0.0-0.41.2-0.2
Locomotion velocity, hab. session 20.70.92.7-1.5-0.70.71.6-1.1-0.2-0.41.1-0.1
Novel to familiar place preference ratio0.20.30.80.60.3-0.3-0.80.10.50.2-0.1-0.9
Novelty place preference0.20.21.10.30.1-0.1-0.6-0.20.50.00.0-1.0
Time in novel zone, NPP test0.30.31.40.40.2-0.2-0.6-0.10.7-0.10.2-1.2
Total zone transitions, NPP test0.40.51.30.61.2-1.2-0.41.0-0.4-0.20.30.3
Total locomotion distance, NPP test0.10.20.5-0.30.4-0.40.50.0-0.60.40.20.7
Locomotion velocity, NPP test0.10.20.4-0.40.2-0.20.6-0.1-0.60.40.20.6
Intraocular pressure0.50.72.60.3-0.00.0-0.80.2-1.01.6-0.51.3
Delta distance traveled before/after self-admin3.33.54.9-1.9-2.22.21.7-2.12.2-0.91.4-1.8
Delta ambulatory time before/after self-admin1.72.13.1-1.5-1.71.71.4-1.71.8-0.61.0-1.4
Parametrial fat weight0.20.41.0-0.9-1.01.00.4-0.5-0.20.30.30.1
Pavlov. Cond. lever latency1.01.22.51.11.4-1.4-1.01.20.4-1.60.6-0.3
Pavlov. Cond. magazine entry latency0.30.41.10.80.1-0.1-0.90.5-0.61.1-0.70.4
Pavlov. Cond. change in total contacts1.01.04.30.5-0.30.3-0.70.2-1.22.1-1.40.8
Pavlov. Cond. index score0.30.41.80.2-0.40.4-0.3-0.0-0.51.3-0.80.4
Pavlov. Cond. latency score0.40.51.9-0.0-0.70.7-0.1-0.3-0.51.4-0.90.4
Pavlov. Cond. lever contacts0.91.13.3-0.9-1.31.30.7-1.1-0.31.8-0.70.3
Pavlov. Cond. magazine entry number0.40.50.9-0.9-0.20.20.9-0.70.9-0.80.6-0.7
Pavlov. Cond. intertrial magazine entries0.70.81.3-1.1-1.11.11.1-1.10.80.9-0.40.1
Pavlov. Cond. lever-magazine prob. diff.0.30.41.80.3-0.30.3-0.50.2-0.71.3-0.80.6
Pavlov. Cond. response bias0.20.31.1-0.1-0.60.60.1-0.4-0.41.1-0.40.3
Pavlov. Cond. lever latency1.01.42.71.31.6-1.6-1.21.3-1.10.3-0.50.8
Pavlov. Cond. magazine entry latency0.50.61.4-0.7-1.21.20.8-0.70.6-0.1-0.1-0.7
Pavlov. Cond. change in total contacts0.20.41.20.0-0.40.40.20.2-0.40.9-1.10.8
Pavlov. Cond. index score0.50.71.6-1.0-1.31.31.1-0.90.5-0.10.1-0.5
Pavlov. Cond. latency score1.01.32.7-1.3-1.61.61.4-1.20.8-0.20.2-0.8
Pavlov. Cond. lever contacts1.11.52.7-1.4-1.61.61.3-1.41.2-0.30.6-0.8
Pavlov. Cond. magazine entry number0.70.81.91.01.4-1.4-1.10.9-0.50.10.00.6
Pavlov. Cond. intertrial magazine entries0.50.73.0-0.40.3-0.30.3-0.20.6-1.71.6-0.3
Pavlov. Cond. lever-magazine prob. diff.0.60.91.7-1.1-1.31.31.2-1.00.6-0.20.2-0.6
Pavlov. Cond. response bias0.30.41.0-0.6-1.01.00.6-0.70.4-0.10.1-0.4
Time in closed arm before self-admin2.63.46.21.71.0-1.0-2.11.1-1.92.5-2.41.9
Time in closed arm after self-admin1.41.54.20.70.4-0.4-0.50.6-1.81.8-1.22.0
Time in open arm before self-admin0.40.41.5-0.30.1-0.10.70.01.2-0.91.0-0.4
Time in open arm after self-admin0.10.20.6-0.2-0.10.10.1-0.10.8-0.5-0.0-0.6
Bone: periosteal estimation0.30.71.5-0.6-0.80.80.5-0.5-0.41.2-1.11.0
Bone: periosteal perimeter0.91.64.3-0.6-1.11.10.7-0.7-0.71.9-2.11.4
Bone: post-yield work0.40.61.10.70.9-0.9-0.71.1-0.2-1.00.7-0.1
Progressive ratio test 1 active lever presses0.40.51.4-0.3-0.20.20.4-0.31.2-0.61.2-1.1
Progressive ratio test 1 breakpoint0.30.41.2-0.1-0.10.10.3-0.21.1-0.51.0-1.0
Progressive ratio test 1 inactive lever presses0.10.20.6-0.3-0.40.40.8-0.30.30.2-0.40.0
Progressive ratio test 2 active lever presses0.70.81.5-1.2-1.01.01.2-1.11.00.40.6-0.4
Progressive ratio test 2 breakpoint0.60.61.1-1.0-0.80.81.1-0.90.90.40.6-0.3
Progressive ratio test 2 inactive lever presses0.50.82.0-1.2-0.90.91.4-1.10.60.50.2-0.0
Incentive Sensitization - Responses0.60.91.7-1.2-1.11.11.1-1.10.21.3-0.40.5
Incentive Sensitization - Breakpoint0.60.81.7-1.1-1.01.01.0-1.00.21.3-0.30.5
Sum of active levers in priming session hrs 5-60.10.10.6-0.0-0.20.20.3-0.20.00.8-0.10.4
Progressive ratio0.20.30.6-0.6-0.60.60.8-0.70.30.20.0-0.4
Food seeking constrained by brief footshock2.22.75.5-2.3-1.81.82.2-2.00.3-0.41.7-0.4
Seeking ratio, punishment vs. effort0.10.10.5-0.20.0-0.0-0.00.0-0.70.40.10.6
Retroperitoneal fat weight1.45.810.8-3.2-3.33.32.8-3.00.81.60.5-0.2
Reaction time number correct0.30.60.90.70.9-0.9-0.80.8-0.0-0.80.70.6
Reaction time mean minus median0.10.31.4-0.2-0.20.20.4-0.4-0.51.2-0.50.0
Reaction time mean minus median AUC0.10.20.7-0.4-0.30.30.6-0.6-0.00.9-0.2-0.4
Reaction time num false alarms0.10.20.40.60.2-0.2-0.40.30.20.6-0.70.3
Reaction time num false alarms AUC0.10.10.70.2-0.10.1-0.1-0.00.80.10.2-0.2
Reaction time trials correct on left0.30.60.90.70.9-0.9-0.80.8-0.0-0.80.70.6
Reaction time trials on left0.30.60.90.70.9-0.9-0.80.80.0-0.80.70.5
Reaction time mean0.20.31.60.30.1-0.1-0.30.20.6-0.60.4-1.3
Reaction time mean AUC0.20.31.20.40.2-0.2-0.40.30.5-0.40.3-1.1
Median of all reaction times0.50.82.90.30.1-0.1-0.50.21.1-1.30.8-1.7
Reaction time omissions0.20.20.60.60.5-0.5-0.40.40.70.10.5-0.5
Reaction time false alarm rate0.10.20.60.1-0.40.40.1-0.20.50.8-0.5-0.2
Reaction time premature initiation rate1.62.35.1-1.4-1.71.71.2-1.6-0.72.2-1.51.0
Reaction time premature initiations0.40.81.9-0.9-0.90.90.5-0.9-0.41.4-0.81.1
Std. dev. reaction times0.10.20.6-0.4-0.40.40.5-0.40.20.40.3-0.8
Reaction time trials completed0.30.60.90.70.9-0.9-0.80.80.0-0.80.70.5
Reaction time trials AUC0.20.40.70.50.7-0.7-0.60.70.1-0.90.80.4
Run reversals in cocaine runway, females0.30.30.8-0.3-0.20.20.5-0.40.7-0.70.6-0.9
Run reversals in cocaine runway, males0.90.91.70.81.0-1.0-0.91.0-1.30.40.71.2
Latency to leave start box in cocaine runway1.92.23.8-2.0-1.61.61.7-1.71.60.11.0-1.3
Latency to leave start box in cocaine runway, F4.04.57.3-2.3-2.22.22.0-2.32.7-1.21.2-2.5
Latency to leave start box in cocaine runway, M0.60.52.4-0.20.2-0.20.00.2-1.11.50.11.0
Std. dev. time between licks in bursts0.60.82.2-1.3-0.70.71.5-0.9-0.60.70.40.5
Total sessions with >9 infusions0.81.03.5-0.9-0.70.70.8-0.71.1-0.61.9-1.0
Short access day 1 total inactive lever presses3.64.76.8-2.6-2.42.42.6-2.62.1-0.81.6-1.7
Short access day 10 total inactive lever presses1.94.68.4-2.8-2.92.92.7-2.80.80.7-1.0-0.4
Short access day 1 total infusions1.52.03.6-1.5-1.31.31.5-1.31.6-0.91.9-1.4
Short access day 10 total infusions1.11.43.1-1.3-1.21.21.3-1.21.1-0.71.8-0.9
Short access total infusions1.11.43.9-1.3-1.01.01.2-1.11.1-0.62.0-0.9
Short access day 1 locomotion1.41.83.5-1.4-1.21.21.1-1.31.9-0.91.4-1.4
Short access day 10 total locomotion0.71.31.8-1.3-1.21.21.0-1.21.3-0.61.3-0.9
Short access total locomotion0.81.02.0-1.0-0.90.90.8-1.01.3-0.51.4-0.8
One hour access (0.3 mA shock)0.40.51.3-1.0-0.90.91.1-0.8-0.20.2-0.10.4
Compulsive drug intake0.10.10.30.20.1-0.1-0.30.1-0.5-0.30.40.0
One hour access (shock baseline)0.20.41.1-0.8-0.70.71.0-0.60.30.3-0.20.4
Social response proportion0.60.71.40.70.4-0.4-0.90.7-1.21.0-1.00.8
Social responses0.50.61.50.60.3-0.3-0.80.4-1.11.0-1.20.7
Social time0.71.01.5-1.0-0.80.80.7-0.81.0-1.21.2-1.1
Soleus weight1.03.04.2-2.1-1.91.91.9-2.01.9-0.91.2-1.5
Bone: stiffness0.20.20.90.30.2-0.2-0.20.5-0.50.7-0.90.1
Tibialis anterior weight0.10.31.7-0.3-0.50.50.2-0.51.3-0.20.2-0.4
Time to tail flick, vehicle, before self-admin1.51.63.3-1.3-1.21.21.2-1.30.01.8-1.7-0.0
Time to tail flick, vehicle, after self-admin0.40.50.9-0.7-1.01.00.8-0.80.60.5-0.8-0.0
Time to tail flick, test, before self-admin0.60.72.2-0.3-0.90.90.1-0.60.61.2-1.5-0.1
Time to tail flick, test, after self-admin2.82.94.5-2.0-2.12.11.5-2.11.80.10.5-1.7
Delta time to tail flick, vehicle, before/after SA0.50.50.80.90.7-0.7-0.90.80.3-0.70.60.1
Delta time to tail flick, test, before/after SA0.70.72.2-0.9-0.40.40.7-0.70.5-0.91.5-0.9
Tibia length0.82.25.71.71.8-1.8-1.42.4-0.9-0.6-0.21.1
Ambulatory time before self-admin0.20.20.40.50.6-0.6-0.70.50.1-0.40.4-0.3
Ambulatory time after self-admin0.30.41.1-0.3-0.50.50.1-0.51.1-0.50.6-0.8
Bone: tissue strength0.80.82.00.41.4-1.4-0.10.8-0.3-1.21.20.1
Total heroin consumption0.10.10.4-0.3-0.30.30.5-0.30.30.60.20.4
Bone: trabecular number0.81.42.41.41.3-1.3-1.20.8-0.11.4-1.60.5
Bone: trabecular spacing1.82.44.2-2.0-1.71.71.9-1.50.8-1.21.7-0.8
Bone: trabecular thickness0.60.83.00.50.3-0.3-0.60.3-0.71.7-1.31.0
Bone: trabecular tissue density1.11.53.51.41.4-1.4-1.21.9-1.20.9-0.70.8
Water consumed over 24 hours0.30.41.1-0.8-0.30.31.0-0.40.6-0.40.7-0.5
Number of responses in last shaping day0.10.10.60.00.3-0.3-0.10.10.8-0.00.6-0.4