Hub : Genes

Ttc14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA NM_001107666.2 0.06 0.04 1.7e-04 0.04 0.03 0.03 0.03 3.4e-05 1.6e-04 1.7e-04 1.4e-04
2 PL alternative polyA XM_063281771.1 0.06 0.04 1.4e-04 0.04 0.03 0.03 0.03 7.5e-05 1.3e-04 3.7e-04 2.0e-04
3 pVTA alternative TSS NM_001107666.2 0.03 0.03 6.7e-03 0.02 0.02 0.02 0.02 8.1e-03 5.8e-03 1.1e-02 1.4e-02
4 pVTA alternative TSS XM_063281771.1 0.03 0.03 7.4e-03 0.01 0.02 0 0.01 2.0e-02 9.6e-03 1.5e-01 2.8e-02
5 Brain intron excision ratio chr2_118584638_118585325 0.06 0.03 2.1e-04 0.05 0.03 0.02 0.04 2.6e-05 3.8e-04 6.5e-03 1.1e-04
6 Brain alternative TSS NM_001107666.2 0.12 0.08 9.0e-08 0.07 0.06 0.07 0.08 4.9e-07 1.3e-06 9.4e-07 1.1e-07
7 Brain alternative TSS XM_063281771.1 0.12 0.08 5.1e-08 0.07 0.07 0.07 0.08 2.8e-07 7.4e-07 5.1e-07 5.7e-08
8 NAcc alternative polyA XM_063281771.1 0.06 0.04 4.7e-07 0.04 0.04 0.04 0.04 2.0e-07 2.6e-06 7.4e-07 6.8e-07
9 PL isoform ratio NM_001107666.2 0.04 0.03 1.3e-03 0.02 0.03 0.02 0.03 2.8e-03 2.6e-04 9.8e-04 5.5e-04
10 RMTg isoform ratio XM_006232257.5 0.2 0.15 3.8e-03 0.09 0.12 0.08 0.13 2.1e-03 4.8e-04 3.3e-03 2.4e-04
11 Brain isoform ratio XM_006232257.5 0.05 0.03 3.9e-04 0.02 0.03 0.03 0.02 2.3e-03 6.0e-04 1.8e-03 2.5e-03
12 NAcc isoform ratio XM_006232257.5 0.08 0.04 7.1e-08 0.04 0.05 0.05 0.05 2.5e-07 5.9e-08 5.5e-08 7.1e-08
13 Brain intron excision ratio chr2_118585015_118585325 0.03 0.02 5.1e-03 0.01 0.02 0.01 0.01 1.7e-02 1.0e-02 2.0e-02 2.3e-02
14 PL isoform ratio XM_006232257.5 0.08 0.06 1.1e-04 0.02 0.03 0.04 0.03 1.1e-03 1.5e-04 9.4e-05 2.4e-04
15 PL intron excision ratio chr2_118584638_118584860 0.03 0.02 7.0e-03 0.01 0.01 0.02 0.01 7.9e-03 1.1e-02 5.6e-03 1.2e-02
16 RMTg alternative polyA NM_001107666.2 0.14 0.1 5.5e-03 0.08 0.07 0.09 0.08 3.7e-03 5.1e-03 1.9e-03 3.2e-03
17 pVTA intron excision ratio chr2_118584638_118585325 0.04 0.03 5.2e-03 0.02 0.02 0.01 0.01 5.5e-03 1.5e-02 2.4e-02 1.9e-02
18 PL intron excision ratio chr2_118584638_118585325 0.04 0.03 4.3e-03 0.01 0.02 0.01 0.01 2.3e-02 3.4e-03 1.4e-02 8.6e-03
19 RMTg alternative polyA XM_063281771.1 0.17 0.11 2.3e-03 0.08 0.08 0.07 0.08 3.4e-03 4.4e-03 5.0e-03 3.1e-03
20 Brain intron excision ratio chr2_118585396_118585795 0.04 0.03 4.8e-03 0.04 0.02 0.02 0.04 1.3e-04 2.5e-03 3.8e-03 1.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.32.37.90.5-0.5-2.72.7-0.4-2.82.8-0.5-0.5-0.00.7-0.5-1.7-1.0-0.1-1.31.80.51.31.8
Area under the delay curve0.50.61.21.1-1.1-1.11.1-1.0-0.70.7-1.00.6-0.8-0.5-1.0-0.0-1.10.80.4-0.0-0.5-0.4-0.0
BMI with tail1.03.66.1-1.61.6-0.90.91.9-1.21.21.6-2.21.82.31.3-2.52.0-2.0-2.42.31.82.32.3
BMI without tail0.41.22.7-0.20.2-1.41.40.6-1.51.50.5-1.00.91.20.2-1.60.0-0.8-1.41.60.71.31.6
Body weight0.31.33.1-0.70.7-0.60.61.4-0.70.70.8-1.41.41.60.3-1.71.3-1.1-1.51.60.61.31.5
Weight adjusted by age0.30.41.3-0.00.01.1-1.10.11.1-1.10.30.30.3-0.40.20.8-1.00.10.4-0.4-0.4-0.5-0.4
Bone surface0.10.20.5-0.10.1-0.50.5-0.0-0.70.70.0-0.20.10.20.1-0.40.0-0.2-0.60.60.40.60.6
Bone volume0.20.41.10.5-0.5-1.01.0-0.3-1.11.1-0.50.0-0.00.1-0.7-0.6-0.60.4-0.50.7-0.30.30.7
Breakpoint value in progressive ratio session2.12.54.9-1.01.0-1.61.60.9-2.22.21.1-1.61.31.71.0-2.20.3-1.5-1.71.81.61.91.8
Number of licking bursts1.22.04.2-0.90.9-1.31.31.0-1.41.40.5-1.51.01.60.3-2.01.9-1.1-1.82.01.11.62.0
Context. condit. distance diff. score2.02.47.31.9-1.9-2.72.7-1.0-2.22.2-1.60.7-0.6-0.2-2.0-1.0-1.81.0-0.31.0-1.2-0.11.0
Locomotion velocity, session 12.83.06.7-2.22.21.3-1.32.00.9-0.92.6-1.82.51.72.4-1.01.4-2.1-1.40.91.61.40.9
Locomotion distance, session 12.02.65.0-2.22.20.8-0.81.80.5-0.52.0-1.91.81.72.0-1.21.8-1.9-1.51.11.81.61.1
Locomotion velocity, session 24.65.311.5-2.92.91.7-1.73.21.5-1.53.0-2.73.42.72.3-1.81.9-2.5-2.11.71.61.81.8
Locomotion distance, session 22.13.05.8-2.32.31.2-1.22.40.9-0.92.0-2.12.02.01.6-1.42.4-1.8-1.51.11.51.41.0
Locomotion velocity, session 30.40.51.0-0.80.80.1-0.10.7-0.30.30.8-0.90.40.90.8-0.70.6-0.9-0.70.51.00.90.5
Locomotion distance, session 30.40.40.9-0.80.80.6-0.60.80.6-0.61.0-0.70.60.70.8-0.40.6-0.8-0.60.50.50.50.4
Stereotopy head waving bouts, day 30.20.20.4-0.50.50.4-0.40.60.3-0.30.6-0.50.60.40.5-0.20.4-0.4-0.30.10.40.30.1
Stereotopy head waving duration, day 30.20.21.0-0.10.1-0.70.7-0.2-1.01.00.1-0.3-0.10.20.3-0.4-0.3-0.2-0.30.10.70.50.2
Locomotion velocity, session 72.02.25.9-2.42.40.9-0.92.00.6-0.61.4-2.01.21.91.1-1.42.1-1.3-1.20.61.51.10.6
Locomotion distance, session 70.40.51.8-0.90.90.7-0.71.10.9-0.9-0.1-0.70.40.8-0.5-0.51.40.1-0.2-0.1-0.2-0.3-0.1
Stereotopy head waving bouts, day 71.11.32.6-0.80.8-0.60.61.2-0.70.71.2-1.31.31.50.8-1.60.2-1.2-1.51.60.81.31.5
Stereotopy head waving duration, day 71.61.93.7-1.01.0-1.11.01.0-1.31.31.3-1.61.21.61.1-1.90.0-1.5-1.71.81.41.81.8
Locomotion velocity, session 81.41.73.9-0.20.2-1.71.70.7-1.71.70.6-1.11.01.30.3-1.90.2-1.0-1.61.90.81.52.0
Locomotion distance, session 80.50.72.00.2-0.2-1.31.30.6-1.11.1-0.3-0.60.50.9-0.8-1.40.0-0.1-0.91.3-0.20.61.2
Degree of sensitization distance0.70.72.00.2-0.20.6-0.60.20.9-0.9-1.10.4-0.2-0.3-1.40.50.41.20.9-1.1-1.1-1.3-1.1
Degree of sensitization stereotypy1.31.42.8-0.50.5-1.31.30.6-1.51.50.8-1.10.71.20.6-1.7-0.1-1.1-1.41.60.91.51.6
Conditioned locomotion1.31.53.41.7-1.7-0.30.3-1.10.1-0.1-1.71.4-1.1-1.2-1.91.0-0.51.61.3-1.1-1.6-1.4-1.0
Cocaine response after cond. corrected3.13.86.32.4-2.4-0.10.1-2.40.1-0.1-2.22.5-1.9-2.4-2.12.1-1.22.22.1-1.9-2.3-2.1-2.0
Cocaine response after cond. not corrected3.03.66.71.9-1.90.5-0.5-2.40.6-0.6-1.82.4-1.9-2.6-1.32.6-1.41.92.3-2.3-1.7-2.0-2.4
Cocaine response before conditioning0.60.73.8-1.21.20.5-0.50.0-0.00.01.3-0.60.00.22.00.1-0.3-1.1-0.2-0.11.70.9-0.1
Saline control response0.20.31.4-0.40.40.6-0.6-0.10.5-0.40.90.00.3-0.21.20.5-0.2-0.7-0.30.30.50.50.2
Bone: connectivity density0.91.33.8-0.10.1-1.71.7-0.1-1.91.90.3-0.70.40.80.3-1.4-0.4-0.7-1.41.51.01.51.5
Bone: cortical apparent density0.30.41.20.2-0.2-0.60.60.8-0.20.20.1-0.41.10.8-0.5-1.0-0.60.0-0.61.0-0.50.21.0
Bone: cortical area0.10.10.30.3-0.3-0.30.3-0.2-0.60.6-0.50.1-0.1-0.0-0.5-0.1-0.00.3-0.20.2-0.20.10.2
Bone: cortical porosity0.70.74.4-0.10.10.2-0.2-1.3-0.50.5-0.40.6-2.1-1.10.71.20.20.10.7-1.11.20.1-1.1
Bone: cortical porosity0.70.74.2-0.10.10.1-0.1-1.2-0.60.6-0.30.5-2.1-1.10.81.20.30.00.7-1.11.30.1-1.1
Bone: cortical thickness0.50.92.30.8-0.8-0.50.5-1.5-0.90.9-1.21.0-1.5-1.2-0.70.9-0.60.90.9-1.0-0.2-0.5-1.0
Bone: cortical thickness1.21.42.5-1.51.50.4-0.41.60.1-0.11.1-1.51.11.51.0-1.21.5-1.3-1.41.11.21.21.2
Bone: cortical tissue density0.30.41.30.2-0.2-0.60.60.9-0.20.20.1-0.51.20.9-0.5-1.1-0.5-0.0-0.71.1-0.50.21.1
Condit. Reinf. active minus inactive responses0.70.72.6-0.70.71.6-1.60.71.5-1.51.0-0.20.70.11.00.60.3-0.50.1-0.30.1-0.0-0.3
Condit. Reinf. active-inactive response ratio0.80.82.00.2-0.21.4-1.4-0.21.4-1.40.10.8-0.3-0.90.21.4-0.30.41.1-1.3-0.7-0.9-1.2
Condit. Reinf. active responses1.82.35.3-1.91.91.4-1.41.61.1-1.12.2-1.51.81.32.3-0.61.2-1.9-1.20.91.51.40.9
Condit. Reinf. inactive responses3.44.17.0-2.32.30.1-0.11.8-0.30.32.5-2.42.02.22.6-1.91.8-2.6-2.42.12.62.62.1
Incentive salience index mean0.70.93.0-0.90.91.7-1.70.81.6-1.61.2-0.30.80.21.20.50.7-0.60.1-0.30.20.0-0.4
Condit. Reinf. lever presses0.91.33.4-1.41.41.2-1.21.00.8-0.81.7-1.01.00.81.8-0.21.4-1.4-0.70.41.30.90.3
Condit. Reinf. active minus inactive responses0.50.61.8-0.60.61.4-1.4-0.11.3-1.30.40.2-0.0-0.40.81.00.3-0.20.5-0.80.4-0.3-0.9
Condit. Reinf. active-inactive response ratio1.21.42.70.8-0.81.0-1.0-0.81.3-1.3-0.81.3-0.9-1.4-0.71.6-0.51.11.4-1.5-1.2-1.4-1.6
Condit. Reinf. active responses1.31.84.7-1.71.72.2-2.21.12.0-2.01.4-0.81.20.41.70.61.0-1.0-0.2-0.31.10.3-0.4
Condit. Reinf. inactive responses2.12.86.1-2.52.51.8-1.81.81.3-1.32.0-1.71.91.42.3-0.51.4-1.8-1.10.51.91.20.5
Condit. Reinf. lever presses0.10.10.3-0.40.40.5-0.50.20.5-0.5-0.1-0.10.1-0.00.10.30.10.20.2-0.40.3-0.2-0.4
Condit. Reinf. lever reinforcers received1.21.64.1-1.61.62.0-2.01.21.9-1.91.3-0.81.30.51.60.40.9-1.0-0.3-0.21.00.4-0.2
Conditioned reinforcement - actives1.22.03.6-1.81.81.1-1.11.91.0-1.01.8-1.51.51.41.7-0.81.9-1.6-1.21.01.31.11.0
Conditioned reinforcement - inactives0.20.30.7-0.70.70.3-0.30.80.2-0.20.7-0.70.60.70.7-0.50.3-0.7-0.50.50.60.50.5
Conditioned locomotion3.03.87.0-2.52.51.2-1.32.40.9-0.92.6-2.22.52.12.4-1.41.8-2.3-1.81.51.81.81.5
Patch foraging indifference point 0 sec0.71.23.00.3-0.3-1.71.70.5-1.51.5-0.4-0.70.51.0-0.8-1.7-0.3-0.2-1.21.70.10.91.7
Patch foraging indifference point AUC2.13.17.2-2.12.1-0.80.71.4-1.21.21.4-2.21.01.91.8-2.01.9-2.0-1.91.62.72.21.6
Delay disc. indifference point, 0s delay0.30.30.7-0.80.80.7-0.70.80.6-0.60.7-0.50.80.40.7-0.1-0.0-0.4-0.10.10.30.10.1
Delay disc. indifference point, 16s delay0.60.61.90.9-0.9-1.41.4-0.9-1.11.1-0.90.4-0.7-0.3-0.8-0.3-0.80.60.00.3-0.2-0.00.3
Delay disc. indifference point, 2s delay0.30.41.10.7-0.7-0.90.9-0.7-0.60.6-0.70.4-0.5-0.2-0.7-0.2-1.10.60.20.1-0.3-0.20.1
Delay disc. indifference point, 24s delay0.60.61.91.0-1.0-1.41.4-0.8-0.90.9-1.00.4-0.6-0.2-1.1-0.4-0.90.6-0.00.3-0.5-0.10.3
Delay disc. indifference point, 4s delay0.10.10.3-0.10.1-0.30.3-0.0-0.50.50.2-0.20.10.20.2-0.3-0.6-0.2-0.20.30.40.30.3
Delay disc. indifference point, 8s delay0.70.81.41.2-1.2-0.50.5-1.1-0.10.1-1.21.0-1.0-0.9-1.20.6-0.81.20.9-0.6-0.9-0.9-0.6
Indifference point function ln k1.93.47.72.1-2.10.7-0.7-1.41.1-1.1-1.62.2-1.1-1.9-2.02.0-2.02.22.0-1.7-2.8-2.3-1.7
Indifference point function log k1.93.47.72.1-2.10.7-0.7-1.41.1-1.1-1.62.2-1.1-1.9-2.02.0-2.02.22.0-1.7-2.8-2.3-1.7
Patch foraging total patch changes 0 sec0.51.02.50.2-0.2-1.61.60.4-1.41.4-0.2-0.60.50.9-0.6-1.5-0.5-0.2-1.11.60.20.91.5
Patch foraging total patch changes 12 sec0.50.72.0-0.00.0-1.41.4-0.0-1.41.4-0.3-0.5-0.10.5-0.1-1.00.3-0.3-0.81.00.90.81.0
Patch foraging total patch changes 18 sec0.60.81.9-0.80.8-0.90.90.6-1.01.00.2-1.10.61.10.2-1.40.7-0.7-1.11.11.01.11.1
Patch foraging total patch changes 24 sec2.44.18.4-1.01.0-2.42.41.3-2.72.70.8-2.01.02.10.7-2.90.9-1.6-2.42.71.92.52.7
Patch foraging total patch changes 6 sec1.72.67.4-0.20.2-2.52.5-0.1-2.72.70.2-1.00.01.00.5-1.90.2-1.0-1.72.11.71.92.0
Patch foraging time to switch 0 sec0.30.71.80.9-0.90.0-0.0-0.80.2-0.2-1.00.9-0.6-0.8-1.30.7-0.41.00.8-0.7-1.3-1.1-0.7
Patch foraging water rate 0 sec0.10.31.00.5-0.5-1.01.0-0.5-1.01.0-0.30.1-0.2-0.1-0.2-0.3-0.90.1-0.10.40.20.30.4
Patch foraging water rate 12 sec0.00.10.90.2-0.20.1-0.1-0.20.1-0.1-0.20.3-0.3-0.3-0.00.3-0.90.10.1-0.1-0.1-0.0-0.2
Patch foraging water rate 18 sec0.20.30.9-0.40.40.4-0.40.70.4-0.40.8-0.41.00.50.6-0.3-0.3-0.6-0.40.50.20.50.5
Patch foraging water rate 24 sec1.41.94.9-0.60.6-1.71.71.0-1.61.60.6-1.41.31.70.3-2.2-0.1-1.0-1.61.91.01.51.9
Patch foraging water rate 6 sec0.10.10.50.4-0.4-0.20.2-0.3-0.20.2-0.00.3-0.0-0.30.10.2-0.7-0.0-0.00.2-0.10.10.1
Seeking ratio, delayed vs. immediate footshock0.30.30.7-0.30.3-0.60.60.2-0.80.80.4-0.4-0.10.40.5-0.60.6-0.6-0.70.80.70.80.7
Distance traveled before self-admin0.81.02.7-0.10.1-1.61.6-0.0-1.61.60.1-0.7-0.10.80.0-1.4-0.2-0.5-1.01.30.71.11.3
Distance traveled after self-admin1.41.82.9-1.41.4-0.60.51.3-0.80.81.2-1.61.11.61.1-1.71.1-1.5-1.61.61.51.71.6
Extensor digitorum longus weight1.35.28.5-2.22.2-0.60.62.3-0.90.92.2-2.72.42.72.1-2.72.4-2.5-2.92.82.62.92.8
Bone: elastic displacement1.41.63.11.4-1.4-0.30.3-1.4-0.30.3-1.51.5-1.4-1.5-1.41.2-1.81.41.4-1.2-1.2-1.2-1.2
Bone: elastic work1.62.13.41.8-1.80.4-0.4-1.40.3-0.3-1.31.8-1.1-1.8-1.21.8-1.81.61.7-1.7-1.6-1.6-1.6
Bone: endosteal estimation0.92.05.4-1.31.30.7-0.72.20.8-0.81.4-1.62.31.80.8-1.41.3-1.2-1.61.60.51.11.6
Bone: endosteal perimeter0.30.71.9-1.01.01.0-1.01.31.0-1.00.5-0.81.10.90.3-0.41.4-0.4-0.50.30.30.20.3
Epididymis fat weight0.00.00.1-0.00.00.3-0.30.10.2-0.20.20.10.40.0-0.10.1-0.10.10.3-0.3-0.3-0.2-0.2
Delta time in closed arm before/after self-admin0.40.41.30.6-0.6-1.11.1-0.9-0.90.9-0.60.4-0.6-0.3-0.6-0.2-0.80.50.00.2-0.20.00.2
Delta time in open arm before/after self-admin0.60.61.00.7-0.70.7-0.7-0.30.8-0.8-0.70.7-0.7-0.8-0.61.00.20.70.9-0.9-0.7-1.0-0.9
Diff in mean of infusions in LGA sessions0.30.31.10.7-0.7-0.50.5-0.6-0.90.9-0.50.5-0.4-0.4-0.40.2-1.00.50.5-0.4-0.4-0.3-0.4
Delay discount exponential model param0.60.71.4-1.11.11.2-1.21.10.8-0.81.0-0.70.90.51.0-0.01.2-0.9-0.40.00.50.40.0
Extinction: sum of active levers before priming0.30.31.2-0.30.31.1-1.10.21.0-1.00.20.20.3-0.20.20.70.10.00.4-0.7-0.3-0.3-0.7
Active lever presses in extinction session 60.10.10.40.2-0.2-0.50.5-0.0-0.60.6-0.1-0.1-0.10.1-0.0-0.30.5-0.1-0.20.30.10.30.3
Bone: final force0.60.93.1-1.21.20.4-0.41.30.1-0.10.9-1.20.71.11.0-0.81.8-1.0-0.90.71.20.90.7
Bone: final moment0.30.41.4-0.70.70.1-0.10.9-0.10.10.5-0.80.50.80.6-0.61.2-0.6-0.70.60.80.70.7
Food consumed during 24 hour testing period0.10.20.8-0.10.1-0.10.10.7-0.00.0-0.5-0.40.20.5-0.9-0.60.80.4-0.30.4-0.4-0.10.4
Glucose0.40.61.4-0.20.21.2-1.2-0.21.2-1.2-0.20.5-0.6-0.6-0.11.10.50.50.8-1.0-0.3-0.8-1.0
Heart weight0.20.30.8-0.00.0-0.10.10.2-0.30.30.9-0.20.90.30.8-0.3-0.4-0.8-0.70.80.10.70.8
Delay discount hyperbolic model param0.60.71.5-1.11.11.1-1.11.10.8-0.81.0-0.60.80.50.9-0.01.2-0.8-0.40.10.50.40.1
Intermittent access intake day 1-15 change0.20.40.8-0.40.4-0.80.80.2-0.80.80.3-0.60.10.60.3-0.90.1-0.5-0.70.80.60.70.8
Intermittent access intake escalation0.30.71.3-0.60.6-0.80.80.5-0.90.90.5-0.90.30.90.5-1.20.2-0.7-1.01.10.91.01.0
Intermittent access intake escalation 20.00.00.1-0.30.3-0.10.10.0-0.10.10.2-0.20.10.20.1-0.20.1-0.1-0.20.20.20.20.1
Intermitt. access day 1 inactive lever presses0.10.31.80.7-0.7-0.10.1-0.6-0.10.1-0.40.6-0.1-0.5-0.40.4-1.30.60.5-0.5-0.5-0.4-0.5
Intermitt. access day 15 inactive lever presses0.10.30.8-0.10.10.9-0.90.10.8-0.80.10.10.4-0.20.10.5-0.80.10.4-0.5-0.2-0.4-0.5
Intermitt. access escalation Index0.10.10.50.2-0.2-0.10.1-0.2-0.10.1-0.40.2-0.7-0.2-0.40.20.70.30.3-0.1-0.2-0.3-0.1
Intermittent access day 1 total infusions1.62.68.8-1.51.53.0-3.01.72.7-2.71.6-0.71.40.51.50.81.4-0.90.0-0.50.3-0.2-0.6
Intermittent access day 15 total infusions1.62.44.2-2.02.00.8-0.82.00.6-0.62.0-1.81.71.71.8-1.21.6-1.8-1.51.31.61.41.2
Intermittent access terminal intake (last 3 days)1.31.73.4-1.71.71.7-1.71.71.4-1.41.6-1.21.31.11.5-0.31.8-1.3-0.70.40.90.60.4
Intermittent access total infusions2.83.35.9-2.42.41.8-1.82.41.5-1.52.4-1.92.21.72.2-0.82.1-2.0-1.41.01.51.30.9
Intermittent access day 1 locomotion2.33.05.2-2.12.12.1-2.12.21.9-1.92.3-1.62.21.42.1-0.41.8-1.7-1.00.61.20.90.6
Intermittent access day 15 total locomotion2.44.46.7-2.62.60.2-0.22.4-0.20.22.6-2.62.42.52.4-2.21.7-2.5-2.32.22.32.32.1
Intermittent access total locomotion4.04.88.4-2.82.80.9-0.92.60.5-0.52.9-2.62.82.52.6-1.91.8-2.6-2.22.02.22.21.9
Intermittent access standard deviation0.00.10.20.1-0.1-0.40.4-0.1-0.40.4-0.1-0.1-0.30.1-0.1-0.2-0.1-0.0-0.20.10.10.20.2
Left kidney weight0.41.65.02.0-2.0-1.21.2-0.8-0.80.8-1.41.1-0.2-0.6-2.2-0.0-1.91.30.50.0-2.2-1.00.1
Right kidney weight0.31.23.60.9-0.9-1.91.9-0.2-1.71.7-0.60.00.20.4-1.1-1.2-1.10.2-0.71.3-0.70.51.3
Cocaine induced anxiety0.30.41.2-0.70.70.8-0.80.70.8-0.80.7-0.50.80.40.7-0.01.1-0.6-0.40.10.30.30.1
Post-drug Anxiety0.70.71.3-1.01.00.8-0.81.10.7-0.71.2-0.91.10.81.1-0.41.0-1.0-0.70.40.70.70.5
Baseline Anxiety0.00.00.4-0.00.0-0.10.10.0-0.10.10.1-0.10.00.10.1-0.1-0.6-0.00.00.10.10.00.1
Tail length0.41.74.01.6-1.6-0.20.2-1.40.1-0.1-1.41.5-0.9-1.4-1.61.1-2.01.51.3-1.1-1.7-1.3-1.1
Length with tail0.10.51.50.6-0.60.7-0.7-0.30.8-0.8-0.50.7-0.1-0.5-0.80.7-0.50.70.6-0.6-1.2-0.8-0.7
Length without tail0.10.31.4-0.60.60.6-0.60.90.5-0.50.6-0.60.70.60.3-0.41.2-0.5-0.40.30.10.30.2
Times rat made contact with spout0.30.41.4-0.40.41.0-1.01.01.2-1.20.0-0.30.50.4-0.4-0.00.40.30.1-0.1-0.6-0.5-0.1
Lifetime Intake2.32.84.9-2.12.11.9-1.92.21.7-1.72.2-1.62.01.52.1-0.51.9-1.7-1.10.71.21.00.7
Liver weight, left1.01.63.5-1.61.61.9-1.91.61.9-1.91.2-1.01.61.00.8-0.21.4-0.9-0.60.20.20.30.2
Liver weight, right0.10.10.30.2-0.20.4-0.40.10.4-0.4-0.30.2-0.0-0.1-0.50.30.10.40.3-0.4-0.6-0.4-0.3
Locomotor activity1.01.64.7-0.10.12.1-2.1-0.61.9-1.90.60.9-0.4-1.41.32.20.3-0.01.1-1.50.1-0.7-1.4
Locomotor testing distance1.11.95.8-1.61.62.1-2.10.91.7-1.71.9-0.70.80.22.40.71.4-1.5-0.4-0.21.50.7-0.1
Locomotor testing rearing0.10.31.8-0.30.30.6-0.6-0.30.3-0.30.90.00.0-0.31.30.60.3-0.7-0.10.00.70.50.0
Locomotion in novel chamber0.70.92.2-1.21.20.6-0.61.10.6-0.61.4-1.01.51.01.2-0.60.7-1.0-0.90.90.80.80.9
Locomotion in novel chamber post-restriction0.00.10.20.2-0.2-0.40.4-0.3-0.40.4-0.10.1-0.4-0.20.00.1-0.00.10.10.10.2-0.10.2
Fecal boli incidents, locomotor time 11.11.62.71.0-1.01.1-1.1-0.61.4-1.4-0.81.3-0.5-1.3-0.91.6-1.41.31.5-1.5-1.6-1.7-1.5
Change in fecal boli incidents, locomotor task1.01.01.9-0.90.9-0.50.50.8-0.70.70.9-1.20.71.10.9-1.21.0-1.2-1.31.21.21.41.2
Time >=10cm from walls, locomotor time 10.10.20.60.2-0.20.2-0.2-0.10.4-0.4-0.50.2-0.5-0.3-0.40.30.80.50.4-0.5-0.2-0.5-0.5
Bouts of movement, locomotor time 10.60.63.20.8-0.80.2-0.2-0.80.1-0.1-0.50.9-0.6-0.9-0.40.9-1.80.70.9-0.9-0.7-0.8-0.9
Total resting periods, locomotor time 11.51.74.61.4-1.40.2-0.2-1.40.2-0.2-1.21.5-1.2-1.5-1.01.5-2.11.41.5-1.4-1.3-1.4-1.4
Rest time, locomotor task time 10.60.71.80.3-0.31.0-1.0-0.21.4-1.4-0.30.7-0.1-0.7-0.31.1-0.70.81.0-1.0-0.8-1.1-1.0
Distance moved, locomotor task time 11.21.83.9-1.11.1-1.01.00.9-1.41.40.8-1.50.71.50.7-1.72.0-1.4-1.71.61.41.71.6
Vertical activity count, locomotor time 10.41.02.2-0.20.2-1.31.30.3-1.51.50.1-0.80.10.9-0.0-1.41.3-0.6-1.21.30.71.11.3
Time >=10cm from walls, locomotor time 20.00.10.20.2-0.20.1-0.1-0.10.3-0.3-0.30.2-0.3-0.2-0.20.30.40.20.2-0.2-0.2-0.2-0.2
Bouts of movement, locomotor time 21.32.15.51.9-1.9-0.70.7-1.9-0.70.7-1.61.6-1.8-1.6-1.31.2-2.41.51.3-1.2-1.1-1.1-1.2
Total resting periods, locomotor time 21.22.25.71.8-1.8-0.40.4-1.9-0.40.4-1.61.7-1.8-1.7-1.31.4-2.41.61.5-1.4-1.2-1.3-1.4
Rest time, locomotor task time 20.20.20.60.4-0.4-0.10.1-0.60.2-0.2-0.60.5-0.6-0.5-0.50.4-0.80.70.5-0.4-0.4-0.5-0.4
Distance moved, locomotor task time 21.41.64.9-1.61.60.5-0.51.3-0.00.01.5-1.41.21.31.5-1.02.2-1.7-1.31.01.41.31.0
Vertical activity count, locomotor time 21.11.52.6-1.51.50.9-0.91.60.8-0.81.6-1.31.51.21.5-0.71.6-1.4-1.00.81.10.90.8
Light reinforcement 10.30.72.00.7-0.70.6-0.6-1.10.6-0.6-0.51.0-1.0-1.3-0.11.4-0.20.60.9-1.0-0.4-0.8-1.0
Light reinforcement 20.10.20.70.8-0.80.2-0.2-0.30.3-0.30.10.60.2-0.5-0.20.5-0.40.20.2-0.0-0.9-0.3-0.1
Bone: marrow area1.02.15.9-1.31.30.6-0.62.30.7-0.71.5-1.72.42.00.8-1.61.3-1.3-1.71.70.51.11.7
Bone: maximum diameter0.10.20.60.0-0.0-0.30.30.3-0.50.5-0.1-0.30.60.4-0.2-0.5-0.1-0.0-0.60.7-0.00.40.7
Bone: maximum force0.10.10.3-0.20.20.6-0.60.50.4-0.40.2-0.20.40.20.10.00.5-0.0-0.20.2-0.00.00.2
Bone: maximum moment0.00.10.10.3-0.30.3-0.30.10.2-0.2-0.10.20.2-0.1-0.20.2-0.00.3-0.00.1-0.4-0.20.2
Mean time between licks in bursts1.43.56.01.9-1.90.7-0.7-1.61.1-1.1-1.82.2-1.3-2.0-1.92.1-1.92.32.3-2.2-2.4-2.4-2.2
Mean num. licks in bursts1.21.83.50.6-0.61.7-1.7-0.41.8-1.8-0.41.2-0.8-1.3-0.31.9-1.51.01.7-1.8-1.1-1.6-1.8
Cd content in liver0.70.82.50.2-0.21.6-1.6-0.21.5-1.50.20.70.1-0.80.31.4-0.30.30.8-0.9-0.7-0.9-0.9
Co content in liver0.10.20.7-0.30.30.5-0.50.10.3-0.30.8-0.10.40.00.80.2-0.0-0.6-0.30.20.10.30.3
Cu content in liver0.30.41.30.7-0.70.4-0.4-0.10.4-0.4-0.50.6-0.1-0.4-0.80.5-0.90.70.5-0.4-1.1-0.8-0.4
Fe content in liver0.70.81.70.7-0.70.7-0.7-0.80.7-0.7-0.61.0-0.6-1.1-0.41.3-0.60.91.2-1.2-0.8-1.1-1.2
K content in liver0.90.81.61.2-1.2-1.11.1-0.9-1.01.0-0.90.8-1.1-0.6-1.10.1-1.30.80.30.1-1.0-0.50.1
Mg content in liver2.32.44.62.1-2.1-1.11.1-1.6-0.90.9-1.91.7-1.8-1.5-2.10.9-1.81.81.2-0.8-1.8-1.5-0.8
Mn content in liver1.61.73.31.6-1.6-0.70.7-1.8-0.60.6-1.51.6-1.7-1.6-1.31.2-1.51.41.2-1.0-1.3-1.3-1.0
Na content in liver0.80.81.8-0.50.5-0.70.71.0-0.60.60.7-1.01.21.10.4-1.3-0.4-0.7-1.11.40.61.01.4
Rb content in liver0.80.92.41.0-1.0-0.40.4-1.6-0.80.8-0.61.2-1.2-1.4-0.21.1-1.40.71.0-0.9-0.4-0.6-0.9
Se content in liver0.30.31.1-0.00.01.1-1.10.01.0-1.00.30.3-0.0-0.40.30.8-0.40.00.5-0.7-0.4-0.5-0.7
Sr content in liver0.90.81.7-1.01.00.2-0.20.90.0-0.01.2-1.00.80.91.3-0.70.8-1.2-0.90.71.21.10.7
Zn content in liver0.50.52.11.1-1.1-0.20.2-0.30.1-0.1-0.90.7-0.3-0.5-1.30.3-0.41.00.5-0.2-1.4-0.9-0.2
Bone: minimum diameter0.10.30.70.3-0.30.6-0.6-0.10.6-0.6-0.50.40.1-0.3-0.70.5-0.20.70.5-0.6-0.9-0.7-0.5
Time in familiar zone, hab. session 10.20.20.8-0.30.30.6-0.60.50.9-0.90.5-0.20.50.30.3-0.00.1-0.2-0.10.1-0.2-0.00.1
Time in novel zone, hab. session 10.90.93.90.4-0.4-1.71.7-0.9-2.02.0-0.50.0-0.8-0.1-0.0-0.5-0.3-0.1-0.40.60.80.70.6
Total zone transitions, hab. session 10.70.92.6-0.90.9-0.50.50.5-0.80.81.1-1.00.30.81.4-0.91.1-1.2-1.00.81.61.30.8
Total locomotion distance, hab. session 11.52.15.6-1.01.0-1.61.60.3-2.02.00.9-1.40.01.21.4-1.71.1-1.4-1.41.42.42.01.4
Locomotion velocity, hab. session 11.52.15.7-1.11.1-1.51.50.3-1.81.80.9-1.4-0.11.21.4-1.61.4-1.4-1.41.32.41.91.3
Time in familiar zone, hab. session 20.91.02.80.9-0.90.3-0.3-1.50.1-0.1-0.21.2-1.0-1.40.31.5-1.70.51.2-1.3-0.4-0.7-1.3
Time in novel zone, hab. session 21.21.22.9-0.50.5-1.21.21.0-1.01.0-0.1-1.10.51.3-0.3-1.71.5-0.5-1.41.70.71.01.7
Total zone transitions, hab. session 20.81.01.8-1.21.20.3-0.31.30.1-0.11.3-1.20.81.11.3-0.81.3-1.3-0.90.71.31.00.7
Total locomotion distance, hab. session 20.60.82.4-1.11.10.0-0.00.8-0.10.11.2-1.00.40.81.4-0.70.8-1.2-0.80.61.61.10.6
Locomotion velocity, hab. session 20.91.22.9-1.41.40.2-0.21.10.1-0.11.4-1.30.61.11.6-0.81.2-1.4-1.00.81.71.20.8
Novel to familiar place preference ratio2.42.69.01.7-1.7-3.03.0-1.5-2.92.9-1.40.6-1.5-0.5-1.1-0.8-0.90.6-0.20.80.10.40.9
Novelty place preference3.13.311.41.7-1.7-3.43.4-1.6-3.33.3-1.50.5-1.7-0.4-1.2-1.0-1.00.6-0.41.10.20.61.1
Time in novel zone, NPP test3.43.712.81.8-1.8-3.63.6-1.6-3.53.5-1.50.5-1.8-0.4-1.3-1.1-1.10.6-0.41.20.20.61.2
Total zone transitions, NPP test1.92.75.8-2.42.41.5-1.52.01.2-1.22.1-1.81.81.62.1-0.82.2-1.7-1.10.51.71.20.5
Total locomotion distance, NPP test1.11.43.5-1.81.81.0-1.01.30.8-0.81.3-1.31.01.11.5-0.51.9-1.2-0.80.41.50.90.4
Locomotion velocity, NPP test1.31.85.0-2.12.11.4-1.41.41.1-1.11.5-1.41.01.11.8-0.42.2-1.3-0.70.21.70.90.2
Intraocular pressure0.50.71.80.4-0.41.2-1.2-0.41.3-1.30.30.80.2-0.90.41.3-0.60.30.9-1.0-0.7-0.9-1.0
Delta distance traveled before/after self-admin0.60.71.6-1.01.01.3-1.31.11.1-1.10.9-0.60.90.50.90.00.9-0.7-0.30.00.40.20.0
Delta ambulatory time before/after self-admin0.60.71.4-1.11.11.0-1.01.20.8-0.81.0-0.81.10.71.0-0.21.0-0.8-0.50.30.60.50.3
Parametrial fat weight0.71.74.3-1.81.81.4-1.41.81.4-1.41.5-1.42.11.31.3-0.71.2-1.2-0.80.60.80.60.5
Pavlov. Cond. lever latency0.81.01.61.3-1.3-1.31.3-1.3-1.21.2-1.20.9-1.0-0.9-1.00.3-1.30.90.6-0.5-0.5-0.5-0.4
Pavlov. Cond. magazine entry latency0.40.51.7-0.60.6-0.10.11.10.0-0.00.1-0.90.71.1-0.2-1.11.3-0.4-0.60.70.30.40.6
Pavlov. Cond. change in total contacts0.10.10.4-0.30.30.6-0.70.30.5-0.50.5-0.10.50.10.40.2-0.1-0.2-0.20.2-0.10.10.2
Pavlov. Cond. index score1.21.63.5-1.51.50.7-0.71.90.7-0.71.2-1.61.61.70.8-1.31.7-1.2-1.31.10.81.01.1
Pavlov. Cond. latency score1.01.32.8-1.41.41.0-1.01.70.9-0.91.1-1.31.41.40.8-0.91.5-1.0-1.00.80.60.70.7
Pavlov. Cond. lever contacts0.91.01.9-1.21.21.3-1.31.41.3-1.31.2-0.91.20.90.9-0.31.2-0.9-0.60.50.30.40.4
Pavlov. Cond. magazine entry number1.11.33.70.9-0.90.5-0.5-1.70.3-0.3-0.51.5-1.5-1.80.11.9-1.20.81.4-1.5-0.4-0.9-1.5
Pavlov. Cond. intertrial magazine entries0.91.02.10.8-0.80.7-0.7-0.90.6-0.6-0.81.1-1.3-1.3-0.51.5-0.60.91.3-1.4-0.8-1.1-1.4
Pavlov. Cond. lever-magazine prob. diff.1.11.33.0-1.41.40.6-0.61.70.6-0.61.0-1.51.41.60.7-1.21.6-1.1-1.11.00.80.91.0
Pavlov. Cond. response bias1.21.43.4-1.01.0-0.10.11.90.0-0.01.0-1.61.71.80.4-1.71.3-1.1-1.41.50.61.01.5
Pavlov. Cond. lever latency0.30.41.50.7-0.70.4-0.4-0.30.7-0.7-0.20.70.0-0.6-0.60.6-0.80.60.6-0.5-1.2-0.8-0.5
Pavlov. Cond. magazine entry latency0.30.41.40.9-0.9-0.50.5-0.2-0.20.2-0.80.40.3-0.1-1.2-0.2-0.60.70.3-0.0-1.1-0.50.0
Pavlov. Cond. change in total contacts0.40.61.5-1.21.21.1-1.10.60.8-0.80.6-0.70.40.40.90.11.2-0.6-0.1-0.41.00.3-0.3
Pavlov. Cond. index score0.20.20.6-0.50.5-0.10.10.6-0.20.20.3-0.60.80.60.2-0.60.5-0.4-0.60.50.50.50.5
Pavlov. Cond. latency score0.10.20.6-0.40.4-0.00.00.6-0.10.10.2-0.60.80.60.1-0.60.7-0.3-0.50.40.30.40.4
Pavlov. Cond. lever contacts0.30.41.1-0.60.6-0.60.60.3-0.80.80.1-0.70.10.60.3-0.80.6-0.5-0.70.51.10.80.5
Pavlov. Cond. magazine entry number0.30.41.20.1-0.10.6-0.6-0.70.5-0.5-0.00.6-1.1-0.90.41.1-0.60.20.7-0.80.1-0.4-0.9
Pavlov. Cond. intertrial magazine entries0.91.33.4-1.61.60.5-0.50.90.0-0.01.5-1.20.60.91.8-0.61.1-1.6-1.20.91.71.30.9
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.60.6-0.10.10.7-0.10.10.4-0.70.90.80.3-0.70.6-0.5-0.60.50.50.50.5
Pavlov. Cond. response bias0.10.20.6-0.40.4-0.50.50.2-0.60.6-0.0-0.50.20.40.2-0.60.3-0.3-0.40.30.80.50.3
Time in closed arm before self-admin0.20.31.10.5-0.5-0.80.8-0.3-1.11.1-0.50.1-0.5-0.0-0.5-0.3-0.30.1-0.10.1-0.00.20.1
Time in closed arm after self-admin0.80.81.51.2-1.2-0.91.0-1.2-1.01.0-1.20.9-1.1-0.8-1.10.3-0.80.90.5-0.4-0.7-0.4-0.4
Time in open arm before self-admin0.30.40.8-0.60.6-0.50.40.4-0.20.20.6-0.60.60.70.6-0.80.2-0.7-0.80.90.60.80.9
Time in open arm after self-admin0.10.10.20.2-0.20.2-0.2-0.00.4-0.4-0.20.3-0.2-0.3-0.20.3-0.00.30.4-0.3-0.3-0.4-0.3
Bone: periosteal estimation0.40.82.5-0.80.80.3-0.31.50.2-0.20.6-1.11.61.30.2-1.11.0-0.6-1.21.20.30.71.2
Bone: periosteal perimeter0.10.10.40.2-0.20.4-0.4-0.30.1-0.1-0.60.4-0.3-0.5-0.30.60.30.50.4-0.6-0.1-0.3-0.5
Bone: post-yield work0.40.61.90.0-0.01.0-1.00.51.4-1.4-0.70.20.2-0.0-1.10.40.81.00.5-0.5-1.1-1.1-0.5
Progressive ratio test 1 active lever presses3.34.17.6-2.62.62.1-2.12.71.8-1.82.6-2.12.31.92.5-0.82.4-2.2-1.51.11.61.41.0
Progressive ratio test 1 breakpoint3.94.78.6-2.82.82.2-2.22.91.8-1.82.8-2.22.52.02.6-0.92.6-2.4-1.71.21.81.51.1
Progressive ratio test 1 inactive lever presses0.81.23.0-1.21.21.7-1.71.31.6-1.61.4-0.71.60.61.30.10.2-0.8-0.30.00.50.20.0
Progressive ratio test 2 active lever presses5.56.511.0-3.33.31.4-1.43.31.0-1.03.2-2.92.92.83.0-1.92.7-3.0-2.52.22.52.42.1
Progressive ratio test 2 breakpoint5.66.410.8-3.33.31.3-1.33.30.9-0.93.2-3.02.92.83.0-2.02.7-3.0-2.52.22.52.42.2
Progressive ratio test 2 inactive lever presses0.71.22.1-1.41.40.7-0.81.50.6-0.61.4-1.31.31.21.3-0.80.9-1.3-1.00.81.10.90.8
Incentive Sensitization - Responses2.43.45.9-2.42.40.8-0.92.40.6-0.62.2-2.21.92.12.0-1.52.2-2.2-1.81.61.91.81.6
Incentive Sensitization - Breakpoint2.63.45.8-2.42.40.8-0.82.40.5-0.52.2-2.21.92.12.0-1.52.2-2.2-1.81.61.91.81.6
Sum of active levers in priming session hrs 5-61.31.33.5-1.41.41.9-1.91.21.6-1.61.4-0.71.40.51.30.30.6-0.8-0.2-0.20.40.2-0.2
Progressive ratio0.10.20.5-0.50.5-0.20.20.3-0.40.40.4-0.5-0.00.40.6-0.40.7-0.6-0.60.60.70.70.5
Food seeking constrained by brief footshock0.30.40.90.7-0.7-0.60.6-0.8-0.70.7-1.00.6-0.9-0.6-0.80.30.20.70.5-0.4-0.4-0.5-0.5
Seeking ratio, punishment vs. effort0.30.40.70.7-0.7-0.80.8-0.6-0.80.8-0.80.4-0.5-0.3-0.9-0.1-0.50.70.4-0.2-0.5-0.4-0.1
Retroperitoneal fat weight0.52.04.7-2.02.01.0-1.01.81.0-1.01.6-1.62.21.61.3-1.01.4-1.4-1.10.91.11.00.9
Reaction time number correct1.42.65.8-2.22.22.4-2.41.72.0-2.01.9-1.31.91.02.10.21.2-1.4-0.5-0.21.20.6-0.1
Reaction time mean minus median0.30.81.11.1-1.10.1-0.1-0.90.1-0.1-0.91.1-0.9-1.0-0.90.9-0.21.01.1-1.0-1.0-1.1-1.0
Reaction time mean minus median AUC0.10.30.60.8-0.8-0.40.4-0.7-0.40.4-0.50.6-0.6-0.6-0.50.3-0.40.60.6-0.4-0.5-0.5-0.4
Reaction time num false alarms0.20.21.2-0.60.60.0-0.00.1-0.10.10.5-0.4-0.20.11.0-0.10.6-0.7-0.30.21.10.50.2
Reaction time num false alarms AUC0.30.41.4-0.90.90.2-0.20.60.1-0.10.6-0.70.10.51.0-0.30.8-0.8-0.40.31.20.60.3
Reaction time trials correct on left1.42.65.8-2.22.22.4-2.41.72.0-2.01.9-1.31.91.02.10.21.2-1.4-0.5-0.21.20.6-0.1
Reaction time trials on left1.32.56.1-2.12.12.5-2.51.62.1-2.11.9-1.11.80.82.00.31.2-1.3-0.4-0.31.10.5-0.2
Reaction time mean1.32.14.80.8-0.81.6-1.6-1.01.6-1.6-0.51.5-1.0-1.6-0.32.1-0.21.11.9-2.2-1.2-1.7-2.1
Reaction time mean AUC1.32.14.90.9-0.91.4-1.4-1.21.4-1.4-0.61.6-1.2-1.8-0.32.2-0.31.11.9-2.2-1.2-1.7-2.1
Median of all reaction times1.52.15.10.7-0.71.7-1.7-1.01.7-1.7-0.41.4-1.0-1.6-0.22.2-0.21.01.9-2.3-1.1-1.7-2.2
Reaction time omissions3.45.09.22.1-2.11.1-1.1-2.21.3-1.3-2.02.6-2.5-2.7-1.72.9-0.62.32.9-3.0-2.2-2.7-3.0
Reaction time false alarm rate0.30.41.20.2-0.2-1.11.1-0.4-1.11.1-0.4-0.1-0.9-0.00.0-0.40.2-0.1-0.20.40.70.40.4
Reaction time premature initiation rate1.41.94.71.9-1.9-1.41.4-1.9-1.11.1-1.51.5-1.6-1.4-1.30.8-2.21.30.8-0.4-1.0-0.7-0.3
Reaction time premature initiations0.10.31.50.5-0.50.1-0.1-0.70.1-0.1-0.30.7-0.4-0.8-0.10.7-1.20.40.4-0.4-0.2-0.3-0.4
Std. dev. reaction times0.40.71.20.9-0.90.3-0.3-0.80.4-0.4-0.71.0-0.8-1.0-0.81.0-0.00.91.0-1.1-1.0-1.0-1.0
Reaction time trials completed1.32.56.1-2.12.12.5-2.51.62.1-2.11.9-1.11.80.82.00.31.2-1.3-0.4-0.31.10.5-0.2
Reaction time trials AUC1.22.35.8-2.02.02.4-2.41.52.0-2.01.8-1.11.70.71.90.31.0-1.2-0.3-0.31.10.4-0.3
Run reversals in cocaine runway, females0.50.51.0-0.90.9-0.10.10.7-0.30.30.8-0.90.60.80.7-0.80.6-0.9-1.00.80.81.00.8
Run reversals in cocaine runway, males0.70.71.5-1.11.10.7-0.71.10.7-0.71.2-0.91.20.81.1-0.40.5-0.9-0.70.70.70.60.6
Latency to leave start box in cocaine runway0.50.60.90.9-0.90.2-0.2-0.70.5-0.5-0.90.9-0.6-0.9-0.90.9-0.30.80.8-0.8-0.9-0.8-0.9
Latency to leave start box in cocaine runway, F0.40.50.80.8-0.80.1-0.1-0.70.2-0.2-0.90.8-0.9-0.8-0.90.70.10.80.7-0.8-0.8-0.8-0.9
Latency to leave start box in cocaine runway, M0.40.40.80.7-0.70.2-0.2-0.70.5-0.5-0.70.7-0.1-0.7-0.70.7-0.90.70.6-0.6-0.7-0.6-0.7
Std. dev. time between licks in bursts0.50.71.10.9-0.90.2-0.2-1.00.3-0.3-0.81.0-0.9-1.1-0.71.0-0.30.91.0-1.0-0.9-0.9-1.0
Total sessions with >9 infusions1.61.95.8-1.31.32.4-2.41.42.3-2.31.5-0.61.40.51.40.61.3-0.8-0.0-0.30.3-0.1-0.3
Short access day 1 total inactive lever presses1.92.64.5-1.41.4-0.90.91.5-1.11.11.5-1.91.71.91.4-2.1-0.1-1.8-1.92.01.82.02.0
Short access day 10 total inactive lever presses0.71.86.11.0-1.0-2.52.5-1.1-2.42.4-1.00.2-0.3-0.0-1.0-1.0-2.20.4-0.30.60.00.50.7
Short access day 1 total infusions0.91.22.1-1.41.41.2-1.21.51.2-1.21.4-1.11.51.01.3-0.40.8-1.1-0.70.50.80.60.6
Short access day 10 total infusions1.72.25.8-1.71.72.4-2.41.72.2-2.21.7-1.01.80.81.60.31.4-1.1-0.4-0.00.60.3-0.0
Short access total infusions1.72.26.0-1.61.62.4-2.41.72.3-2.31.7-0.91.60.71.60.41.3-1.1-0.3-0.10.50.1-0.0
Short access day 1 locomotion1.11.32.4-1.31.30.3-0.31.40.1-0.11.6-1.31.51.31.4-1.10.8-1.3-1.21.21.21.21.2
Short access day 10 total locomotion0.20.31.1-0.50.50.1-0.10.50.0-0.00.9-0.51.00.50.8-0.5-0.1-0.6-0.60.60.50.60.6
Short access total locomotion1.61.94.0-1.61.61.7-1.71.71.5-1.52.0-1.21.91.01.8-0.31.2-1.3-0.80.50.80.70.6
One hour access (0.3 mA shock)2.52.86.8-2.12.10.8-0.82.10.4-0.42.0-2.01.51.81.9-1.32.6-2.0-1.61.41.71.51.4
Compulsive drug intake0.20.31.4-0.60.60.5-0.50.60.5-0.50.6-0.40.30.40.5-0.11.2-0.5-0.30.20.40.20.2
One hour access (shock baseline)1.11.72.9-1.71.70.9-0.91.70.7-0.71.7-1.51.51.41.6-0.91.6-1.5-1.20.91.21.10.8
Social response proportion1.71.93.40.8-0.81.4-1.4-0.71.5-1.5-0.71.4-0.7-1.4-0.81.8-1.21.21.7-1.8-1.6-1.8-1.8
Social responses0.00.10.20.1-0.1-0.30.3-0.1-0.30.30.2-0.00.20.10.2-0.2-0.4-0.1-0.20.30.10.30.3
Social time4.56.212.92.1-2.11.8-1.8-2.42.0-2.0-1.93.0-2.1-3.1-1.63.6-1.72.43.0-3.1-2.6-3.0-3.1
Soleus weight3.510.438.72.3-2.3-6.26.2-2.0-6.16.1-2.00.2-1.50.3-1.9-2.8-1.80.5-1.52.70.41.72.7
Bone: stiffness0.00.00.2-0.00.00.2-0.2-0.00.1-0.1-0.40.1-0.2-0.1-0.30.20.30.40.2-0.3-0.1-0.3-0.3
Tibialis anterior weight2.68.713.9-2.82.8-0.80.83.1-1.31.32.8-3.53.13.62.5-3.52.9-3.3-3.73.73.03.73.6
Time to tail flick, vehicle, before self-admin1.92.03.61.1-1.11.0-1.0-1.11.1-1.1-1.11.6-1.1-1.6-1.01.9-0.91.51.7-1.9-1.5-1.7-1.9
Time to tail flick, vehicle, after self-admin0.70.92.20.3-0.31.4-1.4-0.21.5-1.5-0.20.8-0.2-0.8-0.21.3-0.10.61.0-1.1-0.8-1.0-1.1
Time to tail flick, test, before self-admin1.81.93.81.9-1.9-1.61.6-1.5-1.51.5-2.01.2-1.8-1.1-1.80.3-0.81.30.9-0.6-0.9-0.8-0.6
Time to tail flick, test, after self-admin1.31.44.31.2-1.2-2.12.1-0.8-2.12.1-1.30.3-1.4-0.2-1.2-0.60.30.5-0.20.4-0.10.30.4
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.00.00.8-0.80.10.8-0.80.00.3-0.0-0.40.00.70.20.20.4-0.6-0.3-0.5-0.6
Delta time to tail flick, test, before/after SA0.50.51.1-0.20.2-1.01.00.2-1.11.10.1-0.50.00.60.1-0.90.5-0.5-0.80.90.60.90.9
Tibia length1.02.812.6-1.01.03.2-3.21.73.5-3.50.8-0.21.10.30.31.01.0-0.10.3-0.8-1.0-0.9-0.8
Ambulatory time before self-admin0.40.61.7-0.00.0-1.31.3-0.1-1.31.3-0.0-0.4-0.10.5-0.1-1.0-0.3-0.3-0.70.90.50.80.9
Ambulatory time after self-admin0.70.81.3-1.01.0-0.30.30.9-0.50.50.8-1.10.71.10.8-1.10.6-1.0-1.11.11.01.11.1
Bone: tissue strength5.15.29.02.4-2.40.3-0.2-2.70.3-0.3-2.12.9-2.5-3.0-1.72.8-2.42.62.8-2.7-2.0-2.6-2.7
Total heroin consumption2.93.37.1-0.80.8-2.42.40.8-2.72.70.8-1.70.91.80.7-2.60.3-1.4-2.12.21.72.32.2
Bone: trabecular number2.54.113.3-0.10.1-3.23.2-0.5-3.63.60.3-1.1-0.01.10.7-2.2-0.5-1.2-2.12.41.92.52.5
Bone: trabecular spacing1.52.05.6-0.10.12.1-2.10.62.4-2.4-0.80.5-0.0-0.5-1.01.31.11.11.4-1.8-1.3-1.8-1.8
Bone: trabecular thickness0.50.61.80.7-0.7-1.21.20.1-1.01.0-0.8-0.00.20.4-1.4-0.9-0.70.6-0.50.9-0.90.10.9
Bone: trabecular tissue density1.72.54.21.5-1.50.7-0.7-1.50.8-0.8-1.61.9-1.1-1.8-1.61.9-1.71.91.9-1.8-2.0-2.0-1.8
Water consumed over 24 hours1.21.63.9-1.41.40.1-0.12.00.2-0.11.0-1.71.41.80.5-1.61.5-1.0-1.51.50.81.11.5
Number of responses in last shaping day1.41.52.5-1.21.2-0.50.41.2-0.50.51.2-1.51.41.51.2-1.50.7-1.4-1.51.61.31.51.6