Hub : Genes

Tomm22

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Tomm22 0.08 0.03 7.6e-11 0.09 0.09 0.08 0.09 6.1e-10 8.8e-10 5.2e-09 1.0e-09
2 pVTA gene expression Tomm22 0.12 0.06 2.5e-05 0.03 0.05 0.04 0.03 2.0e-03 4.1e-05 6.1e-04 1.2e-03
3 NAcc mRNA stability Tomm22 0.08 0.03 3.4e-13 0.09 0.09 0.09 0.09 6.0e-13 1.5e-13 5.8e-14 7.0e-14
4 Liver mRNA stability Tomm22 0.29 0.09 0.0e+00 0.34 0.34 0.34 0.34 6.4e-39 6.1e-39 2.5e-39 1.4e-39
5 Adipose gene expression Tomm22 0.04 0.03 2.1e-03 0.03 0.01 0.02 0.03 1.1e-04 9.2e-03 2.8e-03 7.5e-04
6 BLA mRNA stability Tomm22 0.16 0.07 5.0e-08 0.14 0.13 0.12 0.13 6.6e-08 3.4e-07 7.6e-07 1.4e-07
7 Brain mRNA stability Tomm22 0.08 0.04 5.1e-08 0.1 0.09 0.1 0.1 3.6e-09 6.0e-09 1.3e-09 3.8e-09
8 IC mRNA stability Tomm22 0.15 0.09 3.1e-03 0.05 0.05 0.04 0.03 5.2e-03 2.6e-03 1.3e-02 2.4e-02
9 pVTA mRNA stability Tomm22 0.11 0.06 3.7e-06 0.07 0.08 0.07 0.07 1.4e-06 4.7e-07 1.5e-06 2.0e-06
10 Adipose mRNA stability Tomm22 0.07 0.03 6.9e-07 0.01 0.04 0.04 0.03 7.8e-03 9.2e-06 2.5e-05 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.00.10.20.1-0.4-0.10.1-0.50.1-0.1-0.2-0.0-0.4
Area under the delay curve4.65.36.82.6-2.02.42.4-2.22.42.22.42.02.2
BMI with tail0.82.74.4-1.61.0-1.8-1.61.5-1.6-1.6-2.1-1.7-1.7
BMI without tail0.92.74.9-1.61.1-1.8-1.41.7-1.4-1.7-1.9-1.4-2.2
Body weight2.19.212.6-3.42.6-3.0-3.33.5-3.1-3.0-3.0-2.3-2.7
Weight adjusted by age0.61.03.9-1.12.0-1.0-0.71.2-0.7-0.7-0.1-0.6-0.1
Bone surface0.10.20.60.3-0.30.40.3-0.20.30.50.60.30.8
Bone volume0.00.00.10.1-0.30.10.1-0.20.10.10.0-0.0-0.0
Breakpoint value in progressive ratio session0.10.21.00.3-1.00.40.0-0.2-0.00.5-0.10.10.1
Number of licking bursts0.50.81.31.0-0.70.91.1-0.61.20.71.10.70.6
Context. condit. distance diff. score8.09.611.6-3.23.0-3.2-3.23.2-3.4-3.4-3.0-2.8-2.5
Locomotion velocity, session 11.11.23.50.30.70.90.80.10.81.31.61.21.9
Locomotion distance, session 15.16.410.02.7-1.42.72.6-1.72.52.83.22.23.1
Locomotion velocity, session 20.30.42.10.40.20.40.3-0.30.20.90.60.11.5
Locomotion distance, session 27.09.711.23.2-2.83.23.2-2.93.33.43.32.83.1
Locomotion velocity, session 32.83.26.3-1.92.5-1.9-1.62.2-1.5-1.6-1.2-1.8-1.0
Locomotion distance, session 30.20.20.90.00.6-0.20.00.9-0.1-0.20.3-0.6-0.1
Stereotopy head waving bouts, day 30.10.10.2-0.50.2-0.1-0.40.2-0.2-0.1-0.10.30.2
Stereotopy head waving duration, day 30.91.12.3-1.51.5-1.0-1.40.9-1.1-0.8-0.8-0.4-0.1
Locomotion velocity, session 70.40.41.5-0.61.2-0.4-0.70.9-0.7-0.6-0.3-0.2-0.3
Locomotion distance, session 70.30.41.70.50.30.70.30.10.20.01.01.30.4
Stereotopy head waving bouts, day 74.55.110.8-2.53.3-2.3-2.32.4-2.4-1.4-1.8-2.3-0.9
Stereotopy head waving duration, day 74.14.98.7-2.33.0-2.4-2.31.9-2.2-1.6-2.1-2.6-1.2
Locomotion velocity, session 81.01.22.7-1.21.6-0.8-1.31.6-1.6-0.4-0.3-0.50.4
Locomotion distance, session 80.60.91.7-0.91.3-1.1-0.90.8-1.1-1.0-0.8-1.0-0.5
Degree of sensitization distance0.20.30.8-0.50.4-0.2-0.6-0.2-0.5-0.6-0.30.9-0.5
Degree of sensitization stereotypy3.63.99.6-2.13.1-2.0-2.02.1-2.1-0.9-1.5-2.2-0.5
Conditioned locomotion0.40.51.6-0.61.3-0.7-0.80.7-0.8-0.6-0.3-0.1-0.2
Cocaine response after cond. corrected0.30.31.20.30.10.40.4-0.30.40.90.70.61.1
Cocaine response after cond. not corrected0.10.10.50.2-0.20.20.2-0.40.20.60.20.20.7
Cocaine response before conditioning0.20.30.7-0.0-0.5-0.4-0.1-0.2-0.1-0.7-0.8-0.8-0.9
Saline control response1.11.42.2-1.30.9-1.5-0.90.8-0.6-1.4-1.4-1.4-1.3
Bone: connectivity density0.00.10.2-0.30.2-0.2-0.30.2-0.4-0.3-0.2-0.0-0.3
Bone: cortical apparent density0.71.02.1-0.81.0-1.1-0.41.0-0.3-1.4-0.8-1.1-1.3
Bone: cortical area0.10.20.40.0-0.40.30.4-0.40.50.70.10.40.6
Bone: cortical porosity0.20.20.7-0.3-0.5-0.2-0.4-0.4-0.50.4-0.8-0.3-0.1
Bone: cortical porosity0.20.20.5-0.5-0.2-0.2-0.6-0.1-0.60.6-0.7-0.20.3
Bone: cortical thickness0.81.33.81.0-2.01.01.4-1.21.51.00.40.60.5
Bone: cortical thickness2.73.14.71.7-2.21.81.9-1.52.11.71.51.51.5
Bone: cortical tissue density0.70.91.9-0.81.0-1.1-0.41.0-0.3-1.4-0.7-1.0-1.2
Condit. Reinf. active minus inactive responses0.10.10.2-0.0-0.40.10.2-0.00.4-0.00.10.2-0.4
Condit. Reinf. active-inactive response ratio0.40.40.7-0.70.5-0.6-0.50.7-0.2-0.7-0.6-0.5-0.8
Condit. Reinf. active responses0.30.31.8-0.0-0.7-0.20.2-0.40.2-0.6-0.4-0.0-1.3
Condit. Reinf. inactive responses0.40.52.80.1-0.8-0.30.1-0.5-0.1-1.0-0.6-0.2-1.7
Incentive salience index mean0.10.10.40.2-0.50.20.3-0.30.4-0.00.10.5-0.7
Condit. Reinf. lever presses0.10.21.10.2-0.60.10.1-0.40.0-0.3-0.10.4-1.0
Condit. Reinf. active minus inactive responses1.52.03.21.3-1.11.71.2-0.61.21.31.71.61.8
Condit. Reinf. active-inactive response ratio0.60.71.50.6-0.61.00.6-0.30.60.81.01.21.2
Condit. Reinf. active responses1.01.43.71.0-0.71.50.9-0.20.91.21.51.31.9
Condit. Reinf. inactive responses0.60.72.00.7-0.41.10.6-0.00.61.11.00.71.4
Condit. Reinf. lever presses0.40.51.01.0-1.00.80.5-0.80.40.00.70.90.3
Condit. Reinf. lever reinforcers received0.91.33.01.0-0.71.40.8-0.40.81.11.41.41.7
Conditioned reinforcement - actives2.34.05.52.1-2.12.22.0-1.11.62.12.21.92.4
Conditioned reinforcement - inactives3.95.711.42.6-3.42.72.3-1.81.92.12.22.51.8
Conditioned locomotion2.12.75.91.4-2.41.71.7-1.41.41.81.21.41.7
Patch foraging indifference point 0 sec0.20.41.3-0.4-0.4-0.5-0.1-0.70.2-0.9-0.60.1-1.2
Patch foraging indifference point AUC2.73.86.81.9-1.02.22.0-1.41.91.92.62.22.0
Delay disc. indifference point, 0s delay0.30.31.60.2-1.30.10.1-0.80.40.1-0.50.0-0.2
Delay disc. indifference point, 16s delay5.25.77.22.7-1.72.52.6-2.12.52.52.62.12.5
Delay disc. indifference point, 2s delay6.67.39.13.0-2.92.72.8-2.92.92.92.21.62.8
Delay disc. indifference point, 24s delay1.61.84.81.10.31.41.0-0.30.91.42.21.71.9
Delay disc. indifference point, 4s delay2.72.93.51.7-1.41.71.8-1.81.91.71.71.41.8
Delay disc. indifference point, 8s delay2.83.34.72.2-1.72.02.0-1.72.01.42.01.91.3
Indifference point function ln k2.74.86.4-2.31.8-2.4-2.31.6-2.3-2.1-2.5-2.4-1.9
Indifference point function log k2.74.86.4-2.31.8-2.4-2.31.6-2.3-2.1-2.5-2.4-1.9
Patch foraging total patch changes 0 sec0.30.51.4-0.1-0.8-0.30.3-1.20.7-0.8-0.50.2-1.1
Patch foraging total patch changes 12 sec0.60.81.10.7-1.00.80.8-1.11.10.80.71.10.7
Patch foraging total patch changes 18 sec1.32.03.51.2-1.81.61.3-1.51.31.41.31.90.8
Patch foraging total patch changes 24 sec0.61.02.11.1-1.51.01.1-1.21.20.20.71.2-0.1
Patch foraging total patch changes 6 sec1.52.34.21.2-1.51.31.6-2.01.91.11.41.80.8
Patch foraging time to switch 0 sec0.10.20.60.5-0.40.30.2-0.2-0.00.8-0.10.10.6
Patch foraging water rate 0 sec0.20.51.9-0.80.4-0.7-0.40.2-0.1-1.3-0.40.2-1.4
Patch foraging water rate 12 sec0.40.82.1-0.80.2-1.1-0.4-0.3-0.1-1.4-1.1-0.9-1.5
Patch foraging water rate 18 sec0.20.30.8-0.70.8-0.6-0.20.10.0-0.7-0.20.0-0.9
Patch foraging water rate 24 sec2.43.44.8-2.21.8-2.0-2.01.2-1.6-2.1-1.8-1.5-1.9
Patch foraging water rate 6 sec0.91.43.8-1.00.5-1.2-1.00.8-1.0-1.5-1.2-0.9-2.0
Seeking ratio, delayed vs. immediate footshock0.10.10.60.50.40.10.2-0.70.20.10.3-0.00.1
Distance traveled before self-admin2.33.14.62.1-1.61.71.9-2.12.01.31.51.61.5
Distance traveled after self-admin0.60.72.40.6-0.80.90.5-0.60.60.70.91.50.5
Extensor digitorum longus weight0.31.33.71.2-1.60.51.4-1.91.50.70.2-0.10.1
Bone: elastic displacement0.40.41.9-0.81.4-0.6-0.50.6-0.5-0.5-0.1-0.2-0.0
Bone: elastic work0.10.20.9-0.70.9-0.2-0.30.0-0.10.4-0.10.30.6
Bone: endosteal estimation0.20.41.2-0.61.1-0.2-0.90.5-0.90.20.10.30.8
Bone: endosteal perimeter0.40.82.1-1.11.5-0.6-1.20.9-1.30.2-0.5-0.40.4
Epididymis fat weight2.48.311.6-3.22.0-2.8-3.43.3-3.2-2.7-3.2-2.5-2.3
Delta time in closed arm before/after self-admin1.11.02.00.9-1.41.01.1-1.11.30.80.70.70.9
Delta time in open arm before/after self-admin0.10.10.10.20.40.10.20.2-0.10.10.30.20.3
Diff in mean of infusions in LGA sessions0.10.10.3-0.20.30.3-0.40.4-0.40.20.50.50.4
Delay discount exponential model param4.75.26.7-2.61.9-2.4-2.42.2-2.4-2.2-2.4-2.0-2.2
Extinction: sum of active levers before priming1.51.63.61.2-1.11.40.7-0.81.11.91.20.91.9
Active lever presses in extinction session 60.10.10.20.1-0.20.1-0.2-0.1-0.10.50.1-0.00.4
Bone: final force0.30.51.50.3-0.30.70.5-0.60.51.00.60.91.2
Bone: final moment0.30.51.50.3-0.20.70.5-0.50.50.90.71.01.2
Food consumed during 24 hour testing period0.20.20.9-0.1-1.00.40.1-0.10.10.8-0.00.20.6
Glucose0.40.61.9-0.3-1.0-0.3-0.60.6-0.8-0.3-1.1-0.1-1.4
Heart weight1.21.93.6-1.81.9-1.2-1.71.5-1.8-0.9-1.0-0.6-0.6
Delay discount hyperbolic model param4.95.47.1-2.72.1-2.4-2.52.3-2.5-2.2-2.4-1.9-2.3
Intermittent access intake day 1-15 change0.10.20.4-0.3-0.4-0.4-0.10.4-0.4-0.5-0.6-0.6-0.6
Intermittent access intake escalation0.10.20.3-0.2-0.2-0.3-0.10.5-0.3-0.4-0.4-0.6-0.6
Intermittent access intake escalation 20.20.30.8-0.4-0.2-0.5-0.10.4-0.3-0.7-0.6-0.5-0.9
Intermitt. access day 1 inactive lever presses0.10.31.60.3-0.50.6-0.10.1-0.40.30.21.2-0.2
Intermitt. access day 15 inactive lever presses0.40.92.41.0-0.91.20.6-0.40.60.81.21.50.6
Intermitt. access escalation Index0.10.10.60.2-0.8-0.1-0.1-0.40.1-0.1-0.3-0.6-0.3
Intermittent access day 1 total infusions3.75.98.62.5-2.42.82.1-1.71.92.92.52.42.9
Intermittent access day 15 total infusions2.13.14.01.9-1.82.01.8-1.21.51.91.81.52.0
Intermittent access terminal intake (last 3 days)2.63.44.82.0-1.52.11.8-1.31.52.02.01.72.2
Intermittent access total infusions6.77.910.52.9-2.73.22.6-2.12.33.22.92.73.2
Intermittent access day 1 locomotion2.73.45.42.0-2.32.11.6-1.81.71.81.61.91.6
Intermittent access day 15 total locomotion0.71.32.91.2-1.71.50.8-0.50.61.20.91.31.0
Intermittent access total locomotion1.31.64.21.2-2.01.60.9-0.60.71.21.01.61.0
Intermittent access standard deviation0.81.74.01.1-2.01.51.1-1.20.71.40.71.70.8
Left kidney weight2.411.424.4-4.14.3-2.8-4.14.9-4.0-1.8-2.6-2.0-0.4
Right kidney weight3.616.429.2-5.14.3-3.6-5.05.4-5.0-2.6-3.6-2.4-1.5
Cocaine induced anxiety0.40.51.2-0.80.4-0.6-0.90.8-1.1-0.5-0.7-0.6-0.2
Post-drug Anxiety1.71.82.4-1.51.6-1.4-1.41.4-1.3-1.5-1.0-1.1-1.1
Baseline Anxiety0.20.20.80.30.20.20.6-0.40.9-0.00.60.30.1
Tail length0.83.15.5-1.81.3-1.7-1.62.2-1.5-2.1-1.5-1.1-2.3
Length with tail1.87.612.1-3.22.8-2.7-3.03.5-2.8-2.8-2.3-1.9-2.3
Length without tail1.24.06.9-2.62.2-1.9-2.62.0-2.4-1.7-1.7-1.2-0.9
Times rat made contact with spout0.20.21.10.2-1.00.40.40.20.6-0.10.20.5-0.4
Lifetime Intake7.59.212.33.1-3.03.52.8-2.32.53.53.03.03.4
Liver weight, left0.91.63.4-1.31.2-1.2-1.21.8-1.1-1.1-1.1-1.4-0.7
Liver weight, right7.412.816.7-3.73.1-3.6-3.84.1-3.8-3.3-3.6-3.6-3.1
Locomotor activity1.11.73.1-1.80.9-1.5-1.41.2-1.3-1.0-1.5-1.4-0.8
Locomotor testing distance0.10.20.5-0.3-0.5-0.5-0.10.1-0.2-0.5-0.7-0.6-0.7
Locomotor testing rearing0.20.51.1-1.00.0-0.7-0.70.5-0.7-0.1-1.0-0.9-0.3
Locomotion in novel chamber0.40.51.4-0.20.1-0.8-0.20.3-0.0-0.9-0.7-1.1-1.2
Locomotion in novel chamber post-restriction0.40.61.61.0-1.30.70.7-1.20.60.80.3-0.10.3
Fecal boli incidents, locomotor time 11.11.73.71.0-0.81.31.2-1.11.31.31.61.91.1
Change in fecal boli incidents, locomotor task1.91.94.7-1.61.8-1.3-1.42.2-1.2-1.1-0.6-1.3-0.3
Time >=10cm from walls, locomotor time 10.10.10.5-0.70.2-0.2-0.50.4-0.50.2-0.20.10.2
Bouts of movement, locomotor time 10.30.30.9-0.60.4-0.3-0.91.0-0.8-0.2-0.3-0.3-0.1
Total resting periods, locomotor time 10.10.10.1-0.20.20.1-0.40.4-0.30.20.10.20.3
Rest time, locomotor task time 10.10.10.6-0.0-0.10.4-0.20.2-0.20.40.30.80.1
Distance moved, locomotor task time 10.91.32.2-1.21.1-1.3-1.00.7-0.9-1.3-1.2-1.5-0.9
Vertical activity count, locomotor time 10.81.84.0-1.40.4-1.4-1.31.0-1.2-1.7-1.6-1.0-2.0
Time >=10cm from walls, locomotor time 20.20.31.2-0.51.1-0.4-0.70.7-0.6-0.1-0.00.3-0.4
Bouts of movement, locomotor time 20.20.41.90.7-1.40.50.2-0.40.00.5-0.3-0.50.3
Total resting periods, locomotor time 20.50.82.91.1-1.71.00.6-0.80.51.00.2-0.10.8
Rest time, locomotor task time 20.60.81.30.9-0.61.10.7-0.30.51.11.11.11.0
Distance moved, locomotor task time 21.31.52.0-1.41.4-1.4-1.30.7-1.1-1.2-1.3-1.1-1.3
Vertical activity count, locomotor time 21.01.32.3-1.20.6-1.1-1.41.2-1.3-1.1-1.2-0.6-1.5
Light reinforcement 10.10.20.90.2-0.30.30.3-1.00.60.30.20.20.3
Light reinforcement 20.60.91.9-0.80.6-1.0-1.00.7-0.9-0.5-1.3-1.4-0.6
Bone: marrow area0.20.41.3-0.71.1-0.2-0.90.5-0.90.20.10.30.8
Bone: maximum diameter0.20.41.1-1.10.9-0.3-0.80.6-0.60.4-0.4-0.00.6
Bone: maximum force0.61.02.50.5-0.71.00.7-0.60.71.40.91.31.6
Bone: maximum moment0.50.92.50.4-0.50.90.6-0.50.61.30.91.31.6
Mean time between licks in bursts0.30.81.90.90.20.41.2-1.41.40.60.70.11.0
Mean num. licks in bursts0.50.81.3-1.00.2-0.7-1.01.1-1.0-0.9-1.0-0.6-0.9
Cd content in liver0.40.40.9-0.90.4-0.6-0.70.9-0.6-0.3-0.3-0.90.3
Co content in liver1.01.22.21.0-1.51.01.2-1.11.40.80.90.90.7
Cu content in liver2.02.44.42.1-1.71.41.9-1.91.80.91.41.20.3
Fe content in liver1.82.23.8-1.91.7-1.6-1.91.4-1.8-0.8-1.4-0.9-0.8
K content in liver0.10.10.20.5-0.10.30.40.10.20.00.40.4-0.0
Mg content in liver0.20.20.40.6-0.30.40.40.30.10.30.40.60.1
Mn content in liver0.00.00.20.2-0.10.1-0.00.5-0.10.1-0.0-0.30.1
Na content in liver0.10.10.40.0-0.0-0.10.00.4-0.2-0.3-0.10.2-0.6
Rb content in liver1.11.21.91.2-0.61.21.2-1.01.10.91.31.41.2
Se content in liver0.60.72.4-0.70.6-1.1-0.50.8-0.6-0.6-0.9-1.6-0.8
Sr content in liver0.90.82.21.2-1.50.61.1-1.01.0-0.10.30.2-0.5
Zn content in liver0.00.00.2-0.1-0.1-0.1-0.00.5-0.2-0.4-0.0-0.2-0.2
Bone: minimum diameter0.10.10.50.0-0.40.40.1-0.2-0.10.70.10.40.6
Time in familiar zone, hab. session 10.70.71.90.60.40.80.5-0.00.60.71.41.01.3
Time in novel zone, hab. session 11.61.63.4-1.40.3-1.4-1.20.7-1.2-1.1-1.9-1.5-1.4
Total zone transitions, hab. session 10.30.41.00.7-0.10.41.0-0.11.00.30.9-0.10.5
Total locomotion distance, hab. session 10.10.20.6-0.20.4-0.3-0.10.8-0.1-0.50.0-0.7-0.2
Locomotion velocity, hab. session 10.00.10.20.3-0.00.20.30.30.2-0.10.4-0.20.0
Time in familiar zone, hab. session 20.40.40.8-0.30.9-0.7-0.40.6-0.5-0.9-0.4-0.8-0.6
Time in novel zone, hab. session 20.40.42.10.3-1.40.70.4-0.50.30.90.20.60.3
Total zone transitions, hab. session 21.92.44.01.4-1.01.71.6-1.11.61.52.01.81.5
Total locomotion distance, hab. session 21.72.22.81.4-1.11.51.5-1.51.51.51.71.61.4
Locomotion velocity, hab. session 22.12.83.71.6-1.21.71.7-1.71.71.61.91.91.5
Novel to familiar place preference ratio3.33.65.0-2.21.5-2.0-2.22.1-2.0-1.5-1.8-2.0-1.2
Novelty place preference4.54.96.7-2.61.8-2.3-2.52.5-2.3-1.8-2.1-2.4-1.4
Time in novel zone, NPP test5.35.77.7-2.81.9-2.5-2.72.8-2.5-2.0-2.3-2.6-1.6
Total zone transitions, NPP test1.21.73.61.5-0.51.31.7-0.71.61.01.91.11.3
Total locomotion distance, NPP test0.91.32.91.1-0.11.11.2-0.71.30.81.71.21.3
Locomotion velocity, NPP test1.31.93.31.5-0.41.31.6-1.21.71.01.81.31.4
Intraocular pressure0.20.30.7-0.50.8-0.3-0.80.7-0.7-0.2-0.2-0.30.4
Delta distance traveled before/after self-admin1.81.93.8-1.91.3-1.1-1.81.9-1.8-0.8-0.8-0.4-1.0
Delta ambulatory time before/after self-admin0.91.22.9-1.71.2-0.8-1.31.7-1.3-0.4-0.4-0.1-0.4
Parametrial fat weight1.74.06.8-2.01.6-2.1-2.01.8-1.7-2.2-2.1-1.8-2.6
Pavlov. Cond. lever latency0.00.10.1-0.30.3-0.3-0.10.40.0-0.3-0.1-0.20.2
Pavlov. Cond. magazine entry latency1.82.33.21.7-1.31.71.4-1.41.31.81.51.31.5
Pavlov. Cond. change in total contacts3.63.84.42.1-2.02.12.0-2.02.02.11.81.81.6
Pavlov. Cond. index score0.91.11.61.2-1.01.20.9-1.00.71.31.11.20.9
Pavlov. Cond. latency score0.40.50.80.8-0.70.80.6-0.80.40.90.60.80.5
Pavlov. Cond. lever contacts0.50.61.11.0-0.90.80.7-1.10.50.80.60.80.1
Pavlov. Cond. magazine entry number2.02.53.3-1.81.3-1.8-1.61.4-1.5-1.6-1.7-1.5-1.4
Pavlov. Cond. intertrial magazine entries0.10.20.5-0.0-0.40.00.5-0.20.7-0.30.20.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.91.11.51.2-0.91.20.9-1.00.71.21.11.10.9
Pavlov. Cond. response bias1.62.02.81.7-1.21.61.3-1.41.21.51.41.51.1
Pavlov. Cond. lever latency0.10.20.6-0.20.2-0.00.00.70.00.50.1-0.50.6
Pavlov. Cond. magazine entry latency2.02.43.81.6-2.01.41.7-1.91.90.91.21.70.5
Pavlov. Cond. change in total contacts0.20.42.50.20.00.50.2-0.80.30.20.61.60.3
Pavlov. Cond. index score0.50.71.80.8-0.80.70.8-1.20.90.10.71.4-0.0
Pavlov. Cond. latency score0.81.02.41.0-0.90.91.0-1.41.10.30.91.60.0
Pavlov. Cond. lever contacts0.10.20.60.1-0.2-0.1-0.1-0.7-0.1-0.7-0.20.4-0.8
Pavlov. Cond. magazine entry number0.40.51.3-0.70.6-0.6-0.80.9-1.0-0.1-0.7-1.1-0.0
Pavlov. Cond. intertrial magazine entries0.10.20.40.2-0.30.6-0.20.3-0.40.70.40.70.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.60.8-0.80.60.8-1.30.90.00.61.2-0.1
Pavlov. Cond. response bias0.30.51.30.7-0.70.60.5-1.20.50.10.51.1-0.0
Time in closed arm before self-admin0.50.72.60.6-1.20.30.8-1.60.70.1-0.10.4-0.8
Time in closed arm after self-admin0.20.20.9-0.1-0.90.00.1-0.60.2-0.3-0.40.3-0.7
Time in open arm before self-admin0.30.31.2-0.41.1-0.4-0.40.7-0.4-0.6-0.0-0.3-0.3
Time in open arm after self-admin0.20.30.8-0.10.9-0.5-0.10.8-0.3-0.7-0.2-0.5-0.3
Bone: periosteal estimation0.10.20.8-0.40.50.1-0.40.1-0.40.50.10.40.9
Bone: periosteal perimeter0.50.81.8-1.31.3-0.7-1.21.0-1.10.1-0.7-0.40.3
Bone: post-yield work1.42.04.21.2-1.01.61.0-0.61.01.71.81.62.0
Progressive ratio test 1 active lever presses4.96.08.22.5-2.22.82.1-1.92.22.82.52.42.9
Progressive ratio test 1 breakpoint4.65.77.92.4-2.12.72.1-1.82.12.72.52.32.8
Progressive ratio test 1 inactive lever presses5.07.39.32.9-2.93.12.6-2.72.32.82.42.92.4
Progressive ratio test 2 active lever presses4.95.78.52.5-2.62.92.1-1.31.82.72.52.42.6
Progressive ratio test 2 breakpoint5.46.29.12.7-2.63.02.2-1.41.92.92.62.42.8
Progressive ratio test 2 inactive lever presses2.84.67.12.7-2.62.62.1-1.31.52.12.22.11.7
Incentive Sensitization - Responses0.50.71.41.0-1.11.20.8-0.10.51.00.90.80.8
Incentive Sensitization - Breakpoint0.60.81.41.0-1.11.20.7-0.00.41.10.90.80.8
Sum of active levers in priming session hrs 5-60.20.10.6-0.20.0-0.3-0.80.3-0.6-0.2-0.3-0.2-0.3
Progressive ratio0.10.10.20.4-0.40.30.3-0.40.30.20.30.50.2
Food seeking constrained by brief footshock0.30.41.10.5-0.70.60.6-0.60.60.80.40.21.1
Seeking ratio, punishment vs. effort0.10.10.30.2-0.30.40.3-0.40.30.60.30.20.6
Retroperitoneal fat weight2.510.715.3-3.92.9-3.3-3.93.5-3.6-2.6-3.6-3.0-2.2
Reaction time number correct0.10.20.60.10.7-0.3-0.30.7-0.60.0-0.1-0.8-0.1
Reaction time mean minus median0.00.00.2-0.10.0-0.1-0.30.2-0.50.2-0.20.0-0.2
Reaction time mean minus median AUC0.20.61.1-0.80.3-0.7-0.90.8-1.1-0.5-0.9-0.6-0.8
Reaction time num false alarms0.40.61.2-0.8-0.1-0.9-0.50.6-0.2-0.8-1.1-1.0-1.0
Reaction time num false alarms AUC0.30.51.0-0.80.1-0.9-0.40.6-0.1-0.9-0.9-1.0-0.8
Reaction time trials correct on left0.10.20.60.10.7-0.3-0.30.7-0.60.0-0.1-0.8-0.1
Reaction time trials on left0.10.20.60.20.6-0.2-0.30.7-0.50.1-0.0-0.8-0.1
Reaction time mean0.10.20.6-0.40.5-0.4-0.50.5-0.8-0.3-0.3-0.0-0.5
Reaction time mean AUC0.10.20.5-0.30.4-0.3-0.50.5-0.7-0.2-0.2-0.0-0.3
Median of all reaction times0.10.10.3-0.20.5-0.3-0.40.4-0.6-0.2-0.20.1-0.3
Reaction time omissions0.91.43.31.3-1.21.11.2-0.51.01.81.00.31.5
Reaction time false alarm rate0.30.41.0-0.8-0.3-0.7-0.30.30.1-0.9-1.0-0.7-0.8
Reaction time premature initiation rate0.40.61.70.5-1.30.70.4-0.70.31.10.41.00.5
Reaction time premature initiations0.10.30.90.4-0.80.50.1-0.1-0.11.00.20.60.3
Std. dev. reaction times0.30.61.5-0.90.4-0.7-1.01.0-1.2-0.3-0.8-0.5-0.7
Reaction time trials completed0.10.20.60.20.6-0.2-0.30.7-0.50.1-0.0-0.8-0.1
Reaction time trials AUC0.10.20.7-0.00.7-0.3-0.40.8-0.6-0.0-0.2-0.8-0.1
Run reversals in cocaine runway, females0.80.81.6-0.81.2-1.0-0.81.3-0.6-1.0-0.6-0.7-0.9
Run reversals in cocaine runway, males0.40.41.2-0.21.00.20.30.40.50.40.90.41.1
Latency to leave start box in cocaine runway0.30.41.5-0.41.2-0.5-0.60.2-0.70.1-0.4-0.80.3
Latency to leave start box in cocaine runway, F0.40.51.30.50.90.30.6-0.90.50.70.70.21.1
Latency to leave start box in cocaine runway, M2.42.24.5-1.40.9-1.2-1.91.7-2.1-0.9-1.6-1.6-1.0
Std. dev. time between licks in bursts0.40.61.50.60.20.41.0-1.01.20.00.90.90.4
Total sessions with >9 infusions2.83.45.91.6-1.62.21.5-1.21.32.41.72.02.4
Short access day 1 total inactive lever presses2.12.87.21.2-1.01.81.4-1.71.31.61.92.71.6
Short access day 10 total inactive lever presses0.41.02.1-1.00.9-0.6-1.21.3-1.4-1.1-0.50.3-1.2
Short access day 1 total infusions1.31.83.51.2-1.11.61.2-1.00.91.51.31.91.3
Short access day 10 total infusions2.22.84.61.6-1.62.01.3-1.31.22.11.51.72.1
Short access total infusions4.55.78.62.3-2.32.82.0-1.81.82.92.22.52.8
Short access day 1 locomotion0.50.61.50.6-0.80.90.8-0.70.50.70.51.20.4
Short access day 10 total locomotion0.81.45.21.2-2.31.20.8-1.20.50.50.31.7-0.6
Short access total locomotion1.11.43.91.1-2.01.31.0-1.30.91.00.51.50.4
One hour access (0.3 mA shock)7.28.311.13.3-3.33.13.0-2.82.83.02.62.22.6
Compulsive drug intake0.30.31.20.6-0.10.70.50.20.40.61.10.70.4
One hour access (shock baseline)1.92.94.41.9-2.11.81.7-2.11.61.61.11.11.5
Social response proportion0.20.31.00.0-0.1-0.20.3-1.00.30.9-0.3-0.40.6
Social responses1.11.43.10.9-0.80.81.3-1.81.41.31.00.71.4
Social time2.94.06.52.2-2.31.82.3-2.52.21.91.51.61.2
Soleus weight0.41.12.90.9-1.61.11.1-0.41.10.51.11.70.0
Bone: stiffness0.10.20.60.0-0.50.30.1-0.60.20.60.10.70.5
Tibialis anterior weight1.86.112.82.7-3.62.13.0-3.13.11.71.61.41.0
Time to tail flick, vehicle, before self-admin0.10.10.2-0.1-0.50.1-0.30.2-0.40.40.0-0.00.2
Time to tail flick, vehicle, after self-admin0.60.81.8-1.20.8-0.9-0.80.4-0.6-1.2-0.7-0.3-1.4
Time to tail flick, test, before self-admin0.30.30.80.4-0.90.40.7-0.40.80.40.0-0.20.3
Time to tail flick, test, after self-admin0.10.10.20.10.4-0.2-0.0-0.2-0.1-0.50.0-0.0-0.4
Delta time to tail flick, vehicle, before/after SA0.10.10.40.00.20.10.4-0.70.6-0.10.20.6-0.1
Delta time to tail flick, test, before/after SA0.30.31.1-0.10.3-0.5-0.4-0.0-0.5-1.0-0.3-0.3-1.1
Tibia length0.20.41.3-0.30.60.3-0.41.0-0.60.60.50.41.1
Ambulatory time before self-admin1.31.93.31.8-1.31.31.5-1.61.70.81.11.20.9
Ambulatory time after self-admin0.30.31.10.4-0.40.50.5-0.30.50.40.81.00.3
Bone: tissue strength0.30.30.8-0.70.7-0.5-0.60.9-0.6-0.4-0.4-0.4-0.2
Total heroin consumption1.31.62.51.1-1.41.31.1-0.91.41.61.10.81.6
Bone: trabecular number0.20.40.6-0.60.8-0.7-0.60.7-0.6-0.5-0.5-0.7-0.5
Bone: trabecular spacing0.60.82.00.6-0.51.00.3-0.10.31.11.11.41.3
Bone: trabecular thickness0.40.62.0-0.30.2-0.7-0.5-0.0-0.6-0.8-1.0-0.8-1.4
Bone: trabecular tissue density0.40.62.6-0.4-0.1-0.80.0-0.70.2-1.1-0.9-0.5-1.6
Water consumed over 24 hours0.10.20.9-0.1-1.00.30.40.00.60.00.20.5-0.2
Number of responses in last shaping day6.97.611.03.0-3.33.02.8-3.12.53.02.02.52.2